EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000180096 (Gene tree)
Gene ID: 1731
Gene Symbol: SEPT1
Alias: PNUTL3|DIFF6
Full Name: septin 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 17,859 bases
Position: chr16:30,378,133-30,395,991
Accession: 2879
RBP type: canonical RBP
Summary: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000324511	MMR_HSR1	PF01926.23	1.5e-07	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
21688267	Post-transcriptional regulation of the Ras-ERK/MAPK signaling pathway.	J Cell Physiol	2012 Mar	Whelan JT	doi: 10.1002/jcp.22899.
15947549	Proteomic analysis of differentially expressed proteins between metastatic and non-metastatic human colorectal carcinoma cell lines.	Eur J Gastroenterol Hepatol	2005 Jul	Ying-Tao Z	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000570039	SEPT1-208	587	-	-	- (aa)	-	-
ENST00000566517	SEPT1-205	1080	-	-	- (aa)	-	-
ENST00000572252	SEPT1-209	1279	-	ENSP00000459780	70 (aa)	-	I3L2M1
ENST00000567783	SEPT1-206	551	-	-	- (aa)	-	-
ENST00000562152	SEPT1-202	467	-	-	- (aa)	-	-
ENST00000321367	SEPT1-201	1592	XM_017022991	ENSP00000324511	414 (aa)	XP_016878480	J3KNL2
ENST00000573615	SEPT1-210	1616	-	-	- (aa)	-	-
ENST00000563743	SEPT1-203	620	-	-	- (aa)	-	-
ENST00000568577	SEPT1-207	782	-	ENSP00000456541	46 (aa)	-	H3BS52
ENST00000563957	SEPT1-204	2738	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000180096's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa05100	Bacterial invasion of epithelial cells	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000180096's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000180096	SEPT1	86	96.667	ENSAMEG00000007865	SEPT1	99	94.550	Ailuropoda_melanoleuca
ENSG00000180096	SEPT1	100	96.135	ENSANAG00000029084	SEPT1	100	98.638	Aotus_nancymaae
ENSG00000180096	SEPT1	89	97.003	ENSBTAG00000021219	SEPT1	100	97.003	Bos_taurus
ENSG00000180096	SEPT1	100	95.411	ENSCJAG00000002577	SEPT1	100	95.411	Callithrix_jacchus
ENSG00000180096	SEPT1	86	98.333	ENSCAFG00000016576	SEPT1	99	95.902	Canis_familiaris
ENSG00000180096	SEPT1	86	98.333	ENSCAFG00020017813	SEPT1	99	95.902	Canis_lupus_dingo
ENSG00000180096	SEPT1	87	98.361	ENSCHIG00000017447	SEPT1	100	94.133	Capra_hircus
ENSG00000180096	SEPT1	99	90.315	ENSTSYG00000035596	SEPT1	100	96.185	Carlito_syrichta
ENSG00000180096	SEPT1	87	95.082	ENSCAPG00000001347	SEPT1	100	73.913	Cavia_aperea
ENSG00000180096	SEPT1	89	91.935	ENSCPOG00000003088	SEPT1	100	91.599	Cavia_porcellus
ENSG00000180096	SEPT1	93	98.462	ENSCCAG00000030164	SEPT1	100	83.333	Cebus_capucinus
ENSG00000180096	SEPT1	94	100.000	ENSCATG00000037250	SEPT1	100	99.462	Cercocebus_atys
ENSG00000180096	SEPT1	89	93.767	ENSCLAG00000010486	SEPT1	100	94.412	Chinchilla_lanigera
ENSG00000180096	SEPT1	94	100.000	ENSCSAG00000006056	SEPT1	100	99.731	Chlorocebus_sabaeus
ENSG00000180096	SEPT1	100	99.034	ENSCANG00000035786	SEPT1	100	99.034	Colobus_angolensis_palliatus
ENSG00000180096	SEPT1	87	98.361	ENSCGRG00001003374	Sept1	100	94.823	Cricetulus_griseus_chok1gshd
ENSG00000180096	SEPT1	87	98.361	ENSCGRG00000004919	Sept1	100	94.005	Cricetulus_griseus_crigri
ENSG00000180096	SEPT1	94	94.118	ENSDNOG00000014680	SEPT1	91	94.118	Dasypus_novemcinctus
ENSG00000180096	SEPT1	89	95.640	ENSDORG00000011443	Sept1	100	95.640	Dipodomys_ordii
ENSG00000180096	SEPT1	82	96.460	ENSEASG00005013153	SEPT1	100	96.460	Equus_asinus_asinus
ENSG00000180096	SEPT1	93	95.039	ENSECAG00000009390	SEPT1	100	95.039	Equus_caballus
ENSG00000180096	SEPT1	87	98.361	ENSEEUG00000007661	SEPT1	100	94.550	Erinaceus_europaeus
ENSG00000180096	SEPT1	93	93.782	ENSFCAG00000013541	SEPT1	98	93.782	Felis_catus
ENSG00000180096	SEPT1	94	98.485	ENSGGOG00000017024	SEPT1	100	79.810	Gorilla_gorilla
ENSG00000180096	SEPT1	87	100.000	ENSSTOG00000002782	SEPT1	100	97.548	Ictidomys_tridecemlineatus
ENSG00000180096	SEPT1	87	98.361	ENSJJAG00000023131	Sept1	100	94.278	Jaculus_jaculus
ENSG00000180096	SEPT1	86	96.667	ENSLAFG00000027789	SEPT1	99	94.536	Loxodonta_africana
ENSG00000180096	SEPT1	100	98.551	ENSMFAG00000031504	SEPT1	100	98.551	Macaca_fascicularis
ENSG00000180096	SEPT1	94	100.000	ENSMMUG00000021842	SEPT1	99	99.709	Macaca_mulatta
ENSG00000180096	SEPT1	94	100.000	ENSMNEG00000041695	SEPT1	100	87.711	Macaca_nemestrina
ENSG00000180096	SEPT1	94	100.000	ENSMLEG00000039481	SEPT1	100	90.580	Mandrillus_leucophaeus
ENSG00000180096	SEPT1	87	98.361	ENSMAUG00000009531	Sept1	100	95.913	Mesocricetus_auratus
ENSG00000180096	SEPT1	94	93.606	ENSMICG00000011817	SEPT1	98	93.606	Microcebus_murinus
ENSG00000180096	SEPT1	87	98.361	ENSMOCG00000017518	Sept1	100	95.095	Microtus_ochrogaster
ENSG00000180096	SEPT1	87	98.361	MGP_CAROLIEiJ_G0030492	Sept1	100	95.862	Mus_caroli
ENSG00000180096	SEPT1	87	98.361	ENSMUSG00000000486	Sept1	100	95.862	Mus_musculus
ENSG00000180096	SEPT1	87	98.361	MGP_PahariEiJ_G0013702	Sept1	100	95.368	Mus_pahari
ENSG00000180096	SEPT1	87	98.361	MGP_SPRETEiJ_G0031606	Sept1	100	95.862	Mus_spretus
ENSG00000180096	SEPT1	88	95.082	ENSMLUG00000006749	SEPT1	99	95.082	Myotis_lucifugus
ENSG00000180096	SEPT1	89	95.368	ENSNGAG00000021368	Sept1	100	95.368	Nannospalax_galili
ENSG00000180096	SEPT1	88	88.798	ENSMEUG00000000492	SEPT1	100	87.432	Notamacropus_eugenii
ENSG00000180096	SEPT1	89	93.733	ENSOPRG00000007981	SEPT1	100	93.733	Ochotona_princeps
ENSG00000180096	SEPT1	87	96.721	ENSODEG00000014531	SEPT1	100	92.663	Octodon_degus
ENSG00000180096	SEPT1	87	90.164	ENSOANG00000005331	SEPT1	100	86.921	Ornithorhynchus_anatinus
ENSG00000180096	SEPT1	86	100.000	ENSOGAG00000013350	SEPT1	99	97.541	Otolemur_garnettii
ENSG00000180096	SEPT1	86	98.333	ENSOARG00000006135	SEPT1	99	96.196	Ovis_aries
ENSG00000180096	SEPT1	94	100.000	ENSPPAG00000032680	SEPT1	100	83.092	Pan_paniscus
ENSG00000180096	SEPT1	88	95.902	ENSPPRG00000008648	-	100	95.902	Panthera_pardus
ENSG00000180096	SEPT1	93	92.308	ENSPTIG00000006718	SEPT1	96	88.701	Panthera_tigris_altaica
ENSG00000180096	SEPT1	100	100.000	ENSPTRG00000007998	SEPT1	100	100.000	Pan_troglodytes
ENSG00000180096	SEPT1	94	100.000	ENSPANG00000032364	SEPT1	100	90.323	Papio_anubis
ENSG00000180096	SEPT1	87	98.361	ENSPEMG00000023616	Sept1	100	95.368	Peromyscus_maniculatus_bairdii
ENSG00000180096	SEPT1	89	89.373	ENSPCIG00000001537	SEPT1	100	88.011	Phascolarctos_cinereus
ENSG00000180096	SEPT1	87	100.000	ENSPPYG00000007270	-	100	99.351	Pongo_abelii
ENSG00000180096	SEPT1	89	92.916	ENSPCAG00000009042	SEPT1	100	92.916	Procavia_capensis
ENSG00000180096	SEPT1	93	96.923	ENSPCOG00000028121	SEPT1	100	90.821	Propithecus_coquereli
ENSG00000180096	SEPT1	89	97.275	ENSPVAG00000008655	SEPT1	100	97.275	Pteropus_vampyrus
ENSG00000180096	SEPT1	87	98.361	ENSRNOG00000017804	Sept1	100	94.823	Rattus_norvegicus
ENSG00000180096	SEPT1	100	98.792	ENSRBIG00000036580	SEPT1	100	98.792	Rhinopithecus_bieti
ENSG00000180096	SEPT1	100	98.792	ENSRROG00000038708	SEPT1	100	99.194	Rhinopithecus_roxellana
ENSG00000180096	SEPT1	100	95.894	ENSSBOG00000021733	SEPT1	100	95.894	Saimiri_boliviensis_boliviensis
ENSG00000180096	SEPT1	88	88.251	ENSSHAG00000006478	SEPT1	99	86.413	Sarcophilus_harrisii
ENSG00000180096	SEPT1	89	96.730	ENSSSCG00000007800	SEPT1	100	96.730	Sus_scrofa
ENSG00000180096	SEPT1	89	96.730	ENSTTRG00000017272	SEPT1	100	96.730	Tursiops_truncatus
ENSG00000180096	SEPT1	93	95.312	ENSUAMG00000027438	SEPT1	100	95.312	Ursus_americanus
ENSG00000180096	SEPT1	89	96.730	ENSUMAG00000011345	SEPT1	100	96.730	Ursus_maritimus
ENSG00000180096	SEPT1	81	95.238	ENSVVUG00000026116	SEPT1	90	95.238	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003924	GTPase activity	21873635.	IBA	Function
GO:0005515	protein binding	16179162.16189514.17685441.21988832.25416956.26871637.	IPI	Function
GO:0005525	GTP binding	-	IEA	Function
GO:0005815	microtubule organizing center	-	IEA	Component
GO:0005940	septin ring	21873635.	IBA	Component
GO:0008021	synaptic vesicle	21873635.	IBA	Component
GO:0015630	microtubule cytoskeleton	21873635.	IBA	Component
GO:0017157	regulation of exocytosis	21873635.	IBA	Process
GO:0030496	midbody	19799413.	IDA	Component
GO:0031105	septin complex	21873635.	IBA	Component
GO:0042802	identical protein binding	16189514.25416956.	IPI	Function
GO:0060090	molecular adaptor activity	21873635.	IBA	Function
GO:0061640	cytoskeleton-dependent cytokinesis	21873635.	IBA	Process