EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000180917 (Gene tree)
Gene ID: 55783
Gene Symbol: CMTR2
Alias: FLJ11171|AFT|MTr2|FTSJD1
Full Name: cap methyltransferase 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 8,327 bases
Position: chr16:71,281,389-71,289,715
Accession: 25635
RBP type: canonical RBP
Summary: (Cap Methyltransferase 2) is a Protein Coding gene. Among its related pathways are Pathways Affected in Adenoid Cystic Carcinoma. Gene Ontology (GO) annotations related to this gene include methyltransferase activity and mRNA (nucleoside-2'-O-)-methyltransferase activity. An important paralog of this gene is CMTR1.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000337512	FtsJ	PF01728.19	1.8e-30	1	1
ENSP00000411148	FtsJ	PF01728.19	1.8e-30	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000568910	CMTR2-208	632	-	ENSP00000457679	90 (aa)	-	H3BUK2
ENST00000434935	CMTR2-202	4104	XM_011523228	ENSP00000411148	770 (aa)	XP_011521530	Q8IYT2
ENST00000564183	CMTR2-204	565	-	ENSP00000456036	158 (aa)	-	H3BR19
ENST00000565850	CMTR2-206	695	-	ENSP00000456476	132 (aa)	-	H3BS00
ENST00000564690	CMTR2-205	2772	-	-	- (aa)	-	-
ENST00000567610	CMTR2-207	476	-	ENSP00000455080	105 (aa)	-	H3BNZ8
ENST00000338099	CMTR2-201	4869	-	ENSP00000337512	770 (aa)	-	Q8IYT2
ENST00000563876	CMTR2-203	587	-	ENSP00000457399	159 (aa)	-	H3BTZ7

Gene Model

Click here to download ENSG00000180917's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000180917	Blood Pressure	4.7414877E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000180917's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000180917	CMTR2	88	57.857	ENSAPOG00000012087	cmtr2	99	46.727	Acanthochromis_polyacanthus
ENSG00000180917	CMTR2	100	91.195	ENSAMEG00000019632	CMTR2	100	89.714	Ailuropoda_melanoleuca
ENSG00000180917	CMTR2	88	56.944	ENSACIG00000003129	cmtr2	96	46.729	Amphilophus_citrinellus
ENSG00000180917	CMTR2	97	53.797	ENSAOCG00000017042	cmtr2	99	46.065	Amphiprion_ocellaris
ENSG00000180917	CMTR2	88	57.143	ENSAPEG00000013930	cmtr2	96	46.438	Amphiprion_percula
ENSG00000180917	CMTR2	95	54.305	ENSATEG00000002030	cmtr2	98	46.632	Anabas_testudineus
ENSG00000180917	CMTR2	100	68.750	ENSACAG00000014593	CMTR2	98	67.277	Anolis_carolinensis
ENSG00000180917	CMTR2	100	95.325	ENSANAG00000019323	CMTR2	100	95.325	Aotus_nancymaae
ENSG00000180917	CMTR2	88	56.250	ENSACLG00000004652	cmtr2	97	46.958	Astatotilapia_calliptera
ENSG00000180917	CMTR2	90	55.862	ENSAMXG00000003128	cmtr2	97	46.783	Astyanax_mexicanus
ENSG00000180917	CMTR2	100	92.453	ENSBTAG00000047367	CMTR2	100	86.684	Bos_taurus
ENSG00000180917	CMTR2	100	94.545	ENSCJAG00000022068	CMTR2	100	94.545	Callithrix_jacchus
ENSG00000180917	CMTR2	100	91.195	ENSCAFG00000020174	CMTR2	100	89.610	Canis_familiaris
ENSG00000180917	CMTR2	100	91.195	ENSCAFG00020020874	CMTR2	100	89.844	Canis_lupus_dingo
ENSG00000180917	CMTR2	100	90.566	ENSCHIG00000008526	CMTR2	100	86.849	Capra_hircus
ENSG00000180917	CMTR2	100	91.195	ENSCAPG00000009774	CMTR2	100	86.335	Cavia_aperea
ENSG00000180917	CMTR2	100	91.824	ENSCPOG00000015680	CMTR2	99	80.208	Cavia_porcellus
ENSG00000180917	CMTR2	100	93.082	ENSCLAG00000008920	CMTR2	99	87.206	Chinchilla_lanigera
ENSG00000180917	CMTR2	100	97.727	ENSCSAG00000018469	CMTR2	100	97.662	Chlorocebus_sabaeus
ENSG00000180917	CMTR2	100	92.453	ENSCHOG00000000531	CMTR2	85	91.162	Choloepus_hoffmanni
ENSG00000180917	CMTR2	99	72.063	ENSCPBG00000009396	CMTR2	99	72.063	Chrysemys_picta_bellii
ENSG00000180917	CMTR2	89	43.662	ENSCING00000013125	-	99	45.385	Ciona_intestinalis
ENSG00000180917	CMTR2	100	84.906	ENSCGRG00001008188	Cmtr2	100	85.547	Cricetulus_griseus_chok1gshd
ENSG00000180917	CMTR2	100	84.906	ENSCGRG00000012261	Cmtr2	100	85.547	Cricetulus_griseus_crigri
ENSG00000180917	CMTR2	97	51.613	ENSCSEG00000006021	cmtr2	99	45.904	Cynoglossus_semilaevis
ENSG00000180917	CMTR2	97	54.194	ENSCVAG00000005748	cmtr2	99	46.253	Cyprinodon_variegatus
ENSG00000180917	CMTR2	87	55.396	ENSDARG00000036345	cmtr2	97	44.011	Danio_rerio
ENSG00000180917	CMTR2	100	90.566	ENSDNOG00000041497	CMTR2	99	87.630	Dasypus_novemcinctus
ENSG00000180917	CMTR2	100	92.453	ENSDORG00000025105	Cmtr2	100	86.979	Dipodomys_ordii
ENSG00000180917	CMTR2	85	41.912	FBgn0026309	aft	61	38.409	Drosophila_melanogaster
ENSG00000180917	CMTR2	61	58.333	ENSEBUG00000008199	cmtr2	52	47.568	Eptatretus_burgeri
ENSG00000180917	CMTR2	100	88.050	ENSEASG00005013317	CMTR2	100	87.922	Equus_asinus_asinus
ENSG00000180917	CMTR2	100	88.679	ENSECAG00000006573	CMTR2	100	88.052	Equus_caballus
ENSG00000180917	CMTR2	97	54.194	ENSELUG00000011595	cmtr2	99	45.925	Esox_lucius
ENSG00000180917	CMTR2	100	91.195	ENSFCAG00000030250	CMTR2	100	88.672	Felis_catus
ENSG00000180917	CMTR2	100	92.453	ENSFDAG00000018647	CMTR2	99	87.206	Fukomys_damarensis
ENSG00000180917	CMTR2	94	52.000	ENSFHEG00000011809	cmtr2	97	47.285	Fundulus_heteroclitus
ENSG00000180917	CMTR2	91	53.061	ENSGMOG00000003051	cmtr2	98	46.888	Gadus_morhua
ENSG00000180917	CMTR2	100	74.843	ENSGALG00000002356	CMTR2	98	66.710	Gallus_gallus
ENSG00000180917	CMTR2	97	52.564	ENSGAFG00000000227	cmtr2	98	42.487	Gambusia_affinis
ENSG00000180917	CMTR2	94	51.316	ENSGACG00000015882	cmtr2	98	44.664	Gasterosteus_aculeatus
ENSG00000180917	CMTR2	100	71.069	ENSGAGG00000004185	CMTR2	98	72.578	Gopherus_agassizii
ENSG00000180917	CMTR2	88	56.250	ENSHBUG00000015196	cmtr2	97	47.090	Haplochromis_burtoni
ENSG00000180917	CMTR2	100	93.082	ENSHGLG00000013565	CMTR2	99	87.565	Heterocephalus_glaber_female
ENSG00000180917	CMTR2	100	93.082	ENSHGLG00100016028	CMTR2	99	87.565	Heterocephalus_glaber_male
ENSG00000180917	CMTR2	98	50.318	ENSHCOG00000004551	cmtr2	98	46.419	Hippocampus_comes
ENSG00000180917	CMTR2	97	51.948	ENSIPUG00000017648	cmtr2	97	45.191	Ictalurus_punctatus
ENSG00000180917	CMTR2	100	94.969	ENSSTOG00000029180	CMTR2	100	88.542	Ictidomys_tridecemlineatus
ENSG00000180917	CMTR2	97	51.282	ENSKMAG00000008968	cmtr2	99	44.201	Kryptolebias_marmoratus
ENSG00000180917	CMTR2	91	54.167	ENSLBEG00000024048	cmtr2	99	46.164	Labrus_bergylta
ENSG00000180917	CMTR2	99	65.409	ENSLACG00000006760	CMTR2	99	59.067	Latimeria_chalumnae
ENSG00000180917	CMTR2	89	65.493	ENSLOCG00000017595	cmtr2	97	54.679	Lepisosteus_oculatus
ENSG00000180917	CMTR2	100	89.937	ENSLAFG00000008334	CMTR2	100	86.849	Loxodonta_africana
ENSG00000180917	CMTR2	100	98.113	ENSMMUG00000005808	CMTR2	100	97.532	Macaca_mulatta
ENSG00000180917	CMTR2	94	53.595	ENSMAMG00000020867	cmtr2	97	47.763	Mastacembelus_armatus
ENSG00000180917	CMTR2	88	56.250	ENSMZEG00005012998	cmtr2	96	46.082	Maylandia_zebra
ENSG00000180917	CMTR2	100	75.472	ENSMGAG00000015573	CMTR2	100	67.098	Meleagris_gallopavo
ENSG00000180917	CMTR2	100	85.535	ENSMAUG00000008760	Cmtr2	100	84.635	Mesocricetus_auratus
ENSG00000180917	CMTR2	100	85.535	ENSMOCG00000000828	Cmtr2	100	84.156	Microtus_ochrogaster
ENSG00000180917	CMTR2	99	52.500	ENSMMOG00000016204	cmtr2	99	45.096	Mola_mola
ENSG00000180917	CMTR2	100	76.582	ENSMODG00000014267	CMTR2	99	76.610	Monodelphis_domestica
ENSG00000180917	CMTR2	99	51.899	ENSMALG00000000882	cmtr2	99	45.513	Monopterus_albus
ENSG00000180917	CMTR2	100	83.019	MGP_CAROLIEiJ_G0031558	Cmtr2	100	81.250	Mus_caroli
ENSG00000180917	CMTR2	100	80.503	ENSMUSG00000046441	Cmtr2	100	79.297	Mus_musculus
ENSG00000180917	CMTR2	99	81.641	MGP_PahariEiJ_G0023157	Cmtr2	100	81.641	Mus_pahari
ENSG00000180917	CMTR2	100	81.132	MGP_SPRETEiJ_G0032676	Cmtr2	100	79.818	Mus_spretus
ENSG00000180917	CMTR2	100	89.937	ENSMPUG00000019532	CMTR2	100	88.802	Mustela_putorius_furo
ENSG00000180917	CMTR2	100	88.050	ENSMLUG00000000607	CMTR2	100	87.990	Myotis_lucifugus
ENSG00000180917	CMTR2	99	87.632	ENSNGAG00000015133	Cmtr2	99	87.632	Nannospalax_galili
ENSG00000180917	CMTR2	88	56.250	ENSNBRG00000009088	cmtr2	96	47.090	Neolamprologus_brichardi
ENSG00000180917	CMTR2	100	85.535	ENSOPRG00000015162	CMTR2	99	83.947	Ochotona_princeps
ENSG00000180917	CMTR2	88	56.250	ENSONIG00000005719	cmtr2	98	46.867	Oreochromis_niloticus
ENSG00000180917	CMTR2	99	85.137	ENSOCUG00000010218	CMTR2	99	85.137	Oryctolagus_cuniculus
ENSG00000180917	CMTR2	96	46.296	ENSORLG00000008928	cmtr2	92	46.296	Oryzias_latipes
ENSG00000180917	CMTR2	96	46.429	ENSORLG00020007254	cmtr2	92	46.429	Oryzias_latipes_hni
ENSG00000180917	CMTR2	96	46.684	ENSORLG00015005015	cmtr2	92	46.684	Oryzias_latipes_hsok
ENSG00000180917	CMTR2	96	44.895	ENSOMEG00000002443	cmtr2	93	44.895	Oryzias_melastigma
ENSG00000180917	CMTR2	100	92.453	ENSOGAG00000030619	CMTR2	100	88.802	Otolemur_garnettii
ENSG00000180917	CMTR2	100	90.566	ENSOARG00000011167	CMTR2	100	86.554	Ovis_aries
ENSG00000180917	CMTR2	100	91.195	ENSPPRG00000020552	CMTR2	100	88.542	Panthera_pardus
ENSG00000180917	CMTR2	100	86.667	ENSPTIG00000019568	CMTR2	100	85.677	Panthera_tigris_altaica
ENSG00000180917	CMTR2	90	62.238	ENSPKIG00000023749	cmtr2	97	50.723	Paramormyrops_kingsleyae
ENSG00000180917	CMTR2	100	71.698	ENSPSIG00000001359	CMTR2	100	71.018	Pelodiscus_sinensis
ENSG00000180917	CMTR2	97	50.323	ENSPMGG00000002579	cmtr2	99	44.133	Periophthalmus_magnuspinnatus
ENSG00000180917	CMTR2	100	86.792	ENSPEMG00000015578	Cmtr2	100	84.375	Peromyscus_maniculatus_bairdii
ENSG00000180917	CMTR2	87	49.315	ENSPMAG00000007734	cmtr2	97	38.270	Petromyzon_marinus
ENSG00000180917	CMTR2	100	76.582	ENSPCIG00000015810	CMTR2	99	75.690	Phascolarctos_cinereus
ENSG00000180917	CMTR2	97	53.846	ENSPFOG00000018254	cmtr2	98	45.785	Poecilia_formosa
ENSG00000180917	CMTR2	97	53.846	ENSPLAG00000016653	cmtr2	98	45.785	Poecilia_latipinna
ENSG00000180917	CMTR2	97	53.846	ENSPMEG00000006906	cmtr2	98	45.785	Poecilia_mexicana
ENSG00000180917	CMTR2	97	53.205	ENSPREG00000001684	cmtr2	98	45.266	Poecilia_reticulata
ENSG00000180917	CMTR2	100	98.571	ENSPPYG00000007532	CMTR2	100	98.571	Pongo_abelii
ENSG00000180917	CMTR2	100	89.308	ENSPCAG00000009178	CMTR2	99	85.156	Procavia_capensis
ENSG00000180917	CMTR2	88	55.556	ENSPNYG00000015043	cmtr2	97	46.561	Pundamilia_nyererei
ENSG00000180917	CMTR2	97	48.734	ENSPNAG00000014909	cmtr2	98	44.678	Pygocentrus_nattereri
ENSG00000180917	CMTR2	99	80.339	ENSRNOG00000017102	Cmtr2	100	80.339	Rattus_norvegicus
ENSG00000180917	CMTR2	100	76.582	ENSSHAG00000011153	CMTR2	100	73.719	Sarcophilus_harrisii
ENSG00000180917	CMTR2	89	62.759	ENSSFOG00015017483	cmtr2	95	52.083	Scleropages_formosus
ENSG00000180917	CMTR2	97	52.903	ENSSMAG00000000712	cmtr2	99	46.174	Scophthalmus_maximus
ENSG00000180917	CMTR2	96	46.588	ENSSDUG00000019312	cmtr2	97	46.588	Seriola_dumerili
ENSG00000180917	CMTR2	95	51.656	ENSSLDG00000018543	cmtr2	98	46.581	Seriola_lalandi_dorsalis
ENSG00000180917	CMTR2	96	47.334	ENSSPAG00000009337	cmtr2	96	47.334	Stegastes_partitus
ENSG00000180917	CMTR2	100	90.566	ENSSSCG00000033156	CMTR2	100	88.151	Sus_scrofa
ENSG00000180917	CMTR2	100	69.182	ENSTGUG00000006002	CMTR2	100	66.927	Taeniopygia_guttata
ENSG00000180917	CMTR2	85	55.797	ENSTRUG00000018008	cmtr2	95	45.372	Takifugu_rubripes
ENSG00000180917	CMTR2	95	45.600	ENSTNIG00000009304	cmtr2	97	45.600	Tetraodon_nigroviridis
ENSG00000180917	CMTR2	100	90.566	ENSTTRG00000005867	CMTR2	99	84.505	Tursiops_truncatus
ENSG00000180917	CMTR2	100	89.506	ENSUAMG00000014934	CMTR2	100	89.754	Ursus_americanus
ENSG00000180917	CMTR2	100	89.506	ENSUMAG00000017846	CMTR2	100	89.624	Ursus_maritimus
ENSG00000180917	CMTR2	100	91.824	ENSVPAG00000002903	CMTR2	100	89.351	Vicugna_pacos
ENSG00000180917	CMTR2	100	91.195	ENSVVUG00000017698	CMTR2	100	90.104	Vulpes_vulpes
ENSG00000180917	CMTR2	89	61.972	ENSXETG00000015884	cmtr2	99	53.189	Xenopus_tropicalis
ENSG00000180917	CMTR2	94	52.980	ENSXCOG00000011503	cmtr2	98	45.626	Xiphophorus_couchianus
ENSG00000180917	CMTR2	97	52.564	ENSXMAG00000014066	cmtr2	98	45.337	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity	21873635.	IBA	Function
GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity	21310715.	IDA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	21310715.	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	21310715.	IDA	Component
GO:0006370	7-methylguanosine mRNA capping	21873635.	IBA	Process
GO:0006370	7-methylguanosine mRNA capping	21310715.	IDA	Process
GO:0097309	cap1 mRNA methylation	21873635.	IBA	Process
GO:0097310	cap2 mRNA methylation	21873635.	IBA	Process
GO:0097310	cap2 mRNA methylation	21310715.	IDA	Process