EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000181433 (Gene tree)
Gene ID: 55511
Gene Symbol: SAGE1
Alias: SAGE|CT14
Full Name: sarcoma antigen 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 23,857 bases
Position: chrX:135,889,205-135,913,061
Accession: 30369
RBP type: canonical RBP
Summary: This gene belongs to a class of genes that are activated in tumors. These genes are expressed in tumors of different histologic types but not in normal tissues, except for spermatogenic cells and, for some, placenta. The proteins encoded by these genes appear to be strictly tumor specific, and hence may be excellent sources of antigens for cancer immunotherapy. This gene is expressed in sarcomas. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000438276	INT_SG_DDX_CT_C	PF15300.6	1.1e-28	1	1
ENSP00000323191	INT_SG_DDX_CT_C	PF15300.6	2e-28	1	1
ENSP00000359743	INT_SG_DDX_CT_C	PF15300.6	2e-28	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000370709	SAGE1-202	2879	XM_017029621	ENSP00000359743	904 (aa)	XP_016885110	Q9NXZ1
ENST00000324447	SAGE1-201	2952	-	ENSP00000323191	904 (aa)	-	Q9NXZ1
ENST00000537770	SAGE1-203	1824	-	ENSP00000438276	528 (aa)	-	F5H2Z8

Gene Model

Click here to download ENSG00000181433's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000181433's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000181433	SAGE1	100	69.976	ENSCATG00000008610	SAGE1	100	70.455	Cercocebus_atys
ENSG00000181433	SAGE1	100	60.819	ENSCSAG00000007665	SAGE1	100	64.865	Chlorocebus_sabaeus
ENSG00000181433	SAGE1	100	64.252	ENSCANG00000042029	SAGE1	100	64.828	Colobus_angolensis_palliatus
ENSG00000181433	SAGE1	100	97.235	ENSGGOG00000027338	SAGE1	100	97.235	Gorilla_gorilla
ENSG00000181433	SAGE1	100	75.758	ENSMFAG00000043241	-	100	75.758	Macaca_fascicularis
ENSG00000181433	SAGE1	100	76.155	ENSMMUG00000017883	SAGE1	100	76.155	Macaca_mulatta
ENSG00000181433	SAGE1	100	69.976	ENSMNEG00000041463	-	100	70.644	Macaca_nemestrina
ENSG00000181433	SAGE1	100	76.900	ENSMLEG00000033142	-	100	76.900	Mandrillus_leucophaeus
ENSG00000181433	SAGE1	62	57.219	MGP_CAROLIEiJ_G0033085	Ints6l	96	70.270	Mus_caroli
ENSG00000181433	SAGE1	62	58.824	ENSMUSG00000035967	Ints6l	95	70.270	Mus_musculus
ENSG00000181433	SAGE1	62	58.824	MGP_PahariEiJ_G0031627	Ints6l	96	70.270	Mus_pahari
ENSG00000181433	SAGE1	62	59.358	MGP_SPRETEiJ_G0034240	Ints6l	96	70.270	Mus_spretus
ENSG00000181433	SAGE1	100	93.182	ENSNLEG00000002235	SAGE1	100	93.182	Nomascus_leucogenys
ENSG00000181433	SAGE1	93	98.005	ENSPPAG00000031652	-	100	98.005	Pan_paniscus
ENSG00000181433	SAGE1	100	98.341	ENSPTRG00000022306	SAGE1	100	98.341	Pan_troglodytes
ENSG00000181433	SAGE1	100	69.740	ENSPANG00000017255	SAGE1	100	70.265	Papio_anubis
ENSG00000181433	SAGE1	100	93.031	ENSPPYG00000020756	SAGE1	100	93.031	Pongo_abelii
ENSG00000181433	SAGE1	92	47.153	ENSRROG00000032434	-	94	58.111	Rhinopithecus_roxellana

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0032039	integrator complex	21873635.	IBA	Component
GO:0034472	snRNA 3'-end processing	21873635.	IBA	Process

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
26252478	Lack of ADAM2, CALR3 and SAGE1 Cancer/Testis Antigen Expression in Lung and Breast Cancer.	PLoS One	2015 Aug 7	Maheswaran E	doi: 10.1371/journal.pone.0134967

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chrX	135911949	Silent	novel	G839G	0.09
ACC	chrX	135910083	Missense_Mutation	novel	A593S	0.34
ACC	chrX	135911697	Missense_Mutation	novel	M755I	0.92
BLCA	chrX	135906535	Missense_Mutation	novel	M240I	0.88
BLCA	chrX	135908514	Missense_Mutation	novel	M446I	0.19
BLCA	chrX	135905347	Missense_Mutation	novel	H137N	0.92
BLCA	chrX	135905278	Missense_Mutation	novel	E114K	0.85
BLCA	chrX	135912330	Missense_Mutation	rs146979495	R844T	0.26	INT_SG_DDX_CT_C
BLCA	chrX	135910133	Silent	novel	A609A	0.22
BLCA	chrX	135906532	Silent	novel	P239P	0.06
BLCA	chrX	135905376	Missense_Mutation	novel	M146I	0.92
BLCA	chrX	135911242	Missense_Mutation	NA	Q686K	0.08
BLCA	chrX	135901660	Missense_Mutation	novel	K63N	0.06
BLCA	chrX	135905286	Missense_Mutation	NA	R116S	0.17
BRCA	chrX	135906456	Missense_Mutation	NA	V214A	0.3
BRCA	chrX	135909767	Missense_Mutation	NA	T571A	0.13
BRCA	chrX	135912867	Silent	NA	L895L	0.26
BRCA	chrX	135904545	Silent	NA	L97L	0.29
BRCA	chrX	135911251	Missense_Mutation	NA	D689H	0.32
BRCA	chrX	135911315	Missense_Mutation	NA	R710T	0.33
BRCA	chrX	135910429	Missense_Mutation	NA	H627Y	0.12
BRCA	chrX	135906060	Missense_Mutation	novel	M164T	0.08
BRCA	chrX	135908913	Silent	NA	K497K	0.46
BRCA	chrX	135912389	Missense_Mutation	NA	E864K	0.13	INT_SG_DDX_CT_C
BRCA	chrX	135908571	Missense_Mutation	novel	I465M	0.23
BRCA	chrX	135910044	Missense_Mutation	novel	H580D	0.03
BRCA	chrX	135911589	Silent	NA	V719V	0.27
BRCA	chrX	135911938	Nonsense_Mutation	rs782625354	R836*	0.29	INT_SG_DDX_CT_C
BRCA	chrX	135906143	Missense_Mutation	NA	A192S	0.2
BRCA	chrX	135908923	Missense_Mutation	novel	D501H	0.35
BRCA	chrX	135912817	Missense_Mutation	NA	I879F	0.36	INT_SG_DDX_CT_C
BRCA	chrX	135905324	Missense_Mutation	NA	S129L	0.14
CESC	chrX	135906998	Missense_Mutation	NA	S270L	0.13
CESC	chrX	135909753	Missense_Mutation	NA	I566T	0.3
CESC	chrX	135912378	Missense_Mutation	NA	R860I	0.11	INT_SG_DDX_CT_C
CESC	chrX	135907401	Silent	NA	V322V	0.29
CESC	chrX	135908109	Missense_Mutation	novel	L394V	0.09
CESC	chrX	135911712	Missense_Mutation	novel	L760F	0.37
CESC	chrX	135911871	Silent	novel	P813P	0.13
CESC	chrX	135901583	Silent	novel	L38L	0.22
CESC	chrX	135912337	Missense_Mutation	NA	F846L	0.12	INT_SG_DDX_CT_C
CHOL	chrX	135904557	Missense_Mutation	novel	P101S	0.21
COAD	chrX	135906500	Missense_Mutation	rs181135819	R229C	0.16
COAD	chrX	135911297	Missense_Mutation	NA	G704E	0.04
COAD	chrX	135904510	Missense_Mutation	novel	R85M	0.04
COAD	chrX	135909765	Missense_Mutation	NA	S570I	0.53
COAD	chrX	135910552	Missense_Mutation	novel	L668M	0.61
COAD	chrX	135911607	Missense_Mutation	novel	E725D	0.68
COAD	chrX	135907402	Missense_Mutation	novel	I323V	0.1
COAD	chrX	135912992	3'UTR	novel		0.47
COAD	chrX	135910461	Silent	NA	S637S	0.6
COAD	chrX	135908579	Missense_Mutation	NA	A468E	0.48
COAD	chrX	135906500	Missense_Mutation	rs181135819	R229C	0.32
COAD	chrX	135907377	Silent	rs782749871	N314N	0.09
COAD	chrX	135911895	Frame_Shift_Del	NA	*I823Lfs5**	0.48	INT_SG_DDX_CT_C
COAD	chrX	135911244	Silent	NA	Q686Q	0.93
COAD	chrX	135910472	Missense_Mutation	novel	P641H	0.09
COAD	chrX	135912836	Missense_Mutation	rs782694777	A885V	0.17
COAD	chrX	135906469	Silent	NA	P218P	0.28
COAD	chrX	135905342	Missense_Mutation	NA	L135R	0.78
COAD	chrX	135906971	Missense_Mutation	rs150239273	G261D	0.63
COAD	chrX	135906048	Missense_Mutation	rs201111165	R160H	0.06
COAD	chrX	135908143	Missense_Mutation	novel	T405I	0.35
COAD	chrX	135907019	Missense_Mutation	rs781819525	I277T	0.56
COAD	chrX	135906500	Missense_Mutation	rs181135819	R229C	0.18
COAD	chrX	135910517	Missense_Mutation	novel	A656V	0.16
COAD	chrX	135909647	Missense_Mutation	rs782691323	V531I	0.58
COAD	chrX	135911938	Nonsense_Mutation	rs782625354	R836*	0.57	INT_SG_DDX_CT_C
COAD	chrX	135906101	Missense_Mutation	novel	G178C	0.22
COAD	chrX	135912809	Missense_Mutation	NA	V876G	0.26	INT_SG_DDX_CT_C
ESCA	chrX	135912829	Missense_Mutation	novel	E883Q	0.05	INT_SG_DDX_CT_C
ESCA	chrX	135911633	Missense_Mutation	novel	P734H	0.73
ESCA	chrX	135905264	Missense_Mutation	novel	A109G	0.62
ESCA	chrX	135910162	Missense_Mutation	novel	R619K	0.37
GBM	chrX	135907796	Missense_Mutation	novel	Y372N	0.09
GBM	chrX	135911878	In_Frame_Ins	novel	S816delinsYP	0.06
GBM	chrX	135908959	Missense_Mutation	novel	H513D	0.07
GBM	chrX	135911797	Missense_Mutation	novel	K789Q	0.2
GBM	chrX	135911311	Missense_Mutation	NA	C709S	0.31
GBM	chrX	135904520	Silent	NA	N88N	0.26
GBM	chrX	135905275	Missense_Mutation	NA	R113C	0.98
GBM	chrX	135907379	Missense_Mutation	NA	V315G	0.21
GBM	chrX	135905286	Silent	novel	R116R	0.07
GBM	chrX	135911776	Missense_Mutation	novel	N782Y	0.05
GBM	chrX	135908590	Missense_Mutation	novel	I472V	0.05
GBM	chrX	135907733	Nonsense_Mutation	novel	R351*	0.07
HNSC	chrX	135912350	Missense_Mutation	novel	E851Q	0.56	INT_SG_DDX_CT_C
HNSC	chrX	135907323	Silent	novel	V296V	0.06
HNSC	chrX	135908898	Silent	novel	K492K	0.36
HNSC	chrX	135911931	Silent	novel	K833K	0.21
HNSC	chrX	135911651	Nonsense_Mutation	novel	S740*	0.21
KIRC	chrX	135896317	Silent	NA	T25T	0.21
LAML	chrX	135911588	Missense_Mutation	novel	V719A	0.13
LGG	chrX	135906491	Nonsense_Mutation	NA	R226*	0.04
LGG	chrX	135912836	Missense_Mutation	rs782694777	A885V	0.16
LGG	chrX	135907335	Silent	novel	V300V	0.05
LGG	chrX	135908888	Missense_Mutation	rs782681413	R489H	0.94
LGG	chrX	135906475	Silent	rs781786662	N220N	0.23
LGG	chrX	135910438	Missense_Mutation	NA	R630C	0.31
LIHC	chrX	135904504	Missense_Mutation	NA	E83V	0.37
LIHC	chrX	135908119	Missense_Mutation	novel	E397V	0.89
LIHC	chrX	135911801	Missense_Mutation	NA	N790T	0.9
LIHC	chrX	135908094	Frame_Shift_Del	novel	*T389Pfs40**	0.2
LIHC	chrX	135906486	Missense_Mutation	NA	T224S	0.92
LIHC	chrX	135907717	Missense_Mutation	NA	H345Q	0.42
LIHC	chrX	135913031	3'UTR	novel		0.37
LIHC	chrX	135911918	Missense_Mutation	novel	Y829F	0.83	INT_SG_DDX_CT_C
LIHC	chrX	135906041	Missense_Mutation	novel	N158Y	0.18
LIHC	chrX	135905297	Missense_Mutation	novel	G120D	0.12
LIHC	chrX	135901641	Missense_Mutation	NA	S57C	0.1
LUAD	chrX	135911744	Missense_Mutation	NA	S771I	0.29
LUAD	chrX	135911786	Missense_Mutation	novel	A785G	0.28
LUAD	chrX	135896255	Missense_Mutation	novel	P5T	0.88
LUAD	chrX	135910421	Missense_Mutation	NA	A624E	0.48
LUAD	chrX	135908206	Missense_Mutation	NA	P426R	0.37
LUAD	chrX	135901622	Nonsense_Mutation	NA	R51*	0.84
LUAD	chrX	135908520	Silent	NA	N448N	0.84
LUAD	chrX	135907349	Missense_Mutation	novel	M305T	0.17
LUAD	chrX	135911611	Nonsense_Mutation	NA	E727*	0.31
LUAD	chrX	135896329	Frame_Shift_Del	novel		0.32
LUAD	chrX	135911594	Missense_Mutation	novel	H721R	0.49
LUAD	chrX	135909739	Missense_Mutation	NA	L561F	0.07
LUAD	chrX	135906931	Missense_Mutation	novel	T248P	0.34
LUAD	chrX	135901557	Splice_Site	NA	X30_splice	0.1
LUAD	chrX	135910126	Missense_Mutation	novel	N607I	0.04
LUAD	chrX	135911947	Frame_Shift_Del	novel	*Q840Kfs17**	0.29	INT_SG_DDX_CT_C
LUAD	chrX	135912386	Missense_Mutation	rs782593179	V863F	0.4	INT_SG_DDX_CT_C
LUAD	chrX	135901675	Nonsense_Mutation	NA	W68*	0.17
LUAD	chrX	135912828	Silent	novel	L882L	0.21
LUAD	chrX	135909653	Missense_Mutation	novel	Q533E	0.14
LUAD	chrX	135908874	Missense_Mutation	novel	I484M	0.71
LUAD	chrX	135901675	Missense_Mutation	novel	W68C	0.49
LUAD	chrX	135911633	Missense_Mutation	NA	P734L	0.24
LUAD	chrX	135905249	Splice_Region	novel		0.48
LUAD	chrX	135905260	Missense_Mutation	novel	I108F	0.38
LUAD	chrX	135905373	Silent	novel	S145S	0.21
LUAD	chrX	135907342	Missense_Mutation	rs781934045	E303K	0.08
LUAD	chrX	135911821	Missense_Mutation	NA	D797Y	0.25
LUAD	chrX	135905339	Missense_Mutation	NA	Q134P	0.18
LUAD	chrX	135907323	Silent	novel	V296V	0.69
LUAD	chrX	135910097	Silent	NA	V597V	0.48
LUAD	chrX	135907725	Missense_Mutation	novel	C348Y	0.44
LUAD	chrX	135910088	Silent	novel	S594S	0.27
LUAD	chrX	135909676	Missense_Mutation	NA	M540I	0.16
LUAD	chrX	135908145	Missense_Mutation	NA	P406S	0.24
LUAD	chrX	135908568	Silent	novel	L464L	0.15
LUAD	chrX	135906106	Silent	NA	P179P	0.26
LUAD	chrX	135908205	Missense_Mutation	novel	P426T	0.33
LUAD	chrX	135908572	Missense_Mutation	NA	N466Y	0.57
LUAD	chrX	135911905	Missense_Mutation	NA	D825Y	0.78	INT_SG_DDX_CT_C
LUAD	chrX	135907403	Missense_Mutation	rs782261322	I323T	0.12
LUSC	chrX	135905369	Missense_Mutation	novel	P144L	0.74
LUSC	chrX	135905392	Missense_Mutation	NA	H152D	0.25
LUSC	chrX	135911596	Missense_Mutation	novel	D722Y	0.42
LUSC	chrX	135909749	Missense_Mutation	novel	G565R	0.8
LUSC	chrX	135906951	Silent	novel	P254P	0.64
LUSC	chrX	135905324	Nonsense_Mutation	NA	S129*	0.68
LUSC	chrX	135907764	Missense_Mutation	novel	N361T	0.68
LUSC	chrX	135910059	Nonsense_Mutation	novel	E585*	0.24
LUSC	chrX	135912802	Nonsense_Mutation	rs782732879	K874*	0.09	INT_SG_DDX_CT_C
LUSC	chrX	135911947	Frame_Shift_Del	novel	*Q840Kfs17**	0.9	INT_SG_DDX_CT_C
LUSC	chrX	135908127	Missense_Mutation	novel	D400N	0.63
LUSC	chrX	135911576	Splice_Region	novel		0.69
LUSC	chrX	135910102	Missense_Mutation	rs781798413	S599L	0.15
LUSC	chrX	135911905	Missense_Mutation	NA	D825N	0.54	INT_SG_DDX_CT_C
LUSC	chrX	135909757	Silent	rs782344378	P567P	0.11
LUSC	chrX	135908474	Splice_Region	novel		0.1
LUSC	chrX	135910544	Missense_Mutation	novel	T665N	0.07
LUSC	chrX	135907778	Missense_Mutation	novel	V366F	0.36
LUSC	chrX	135905311	Missense_Mutation	novel	D125H	0.43
LUSC	chrX	135907042	Missense_Mutation	NA	P285S	0.31
LUSC	chrX	135908616	Splice_Region	novel	L480L	0.84
LUSC	chrX	135907351	Missense_Mutation	novel	E306K	0.4
LUSC	chrX	135907057	Missense_Mutation	novel	N290D	0.11
LUSC	chrX	135912802	Frame_Shift_Del	NA	*V876Lfs3**	0.74	INT_SG_DDX_CT_C
LUSC	chrX	135908092	Missense_Mutation	novel	A388D	0.53
LUSC	chrX	135905351	Missense_Mutation	novel	M138T	0.58
LUSC	chrX	135912997	3'UTR	novel		0.29
LUSC	chrX	135907787	Missense_Mutation	novel	G369R	0.28
LUSC	chrX	135907357	Missense_Mutation	NA	D308Y	0.66
LUSC	chrX	135907784	Frame_Shift_Del	novel	*P368Qfs14**	0.73
LUSC	chrX	135909651	Missense_Mutation	novel	T532N	0.16
LUSC	chrX	135911258	Missense_Mutation	rs782511869	S691C	0.27
LUSC	chrX	135905251	Splice_Site	NA	X105_splice	0.3
LUSC	chrX	135911582	Missense_Mutation	NA	A717D	0.75
OV	chrX	135910420	Missense_Mutation	novel	A624T	0.04
OV	chrX	135910422	Silent	novel	A624A	0.03
OV	chrX	135911922	Missense_Mutation	novel	Q830H	0.08	INT_SG_DDX_CT_C
OV	chrX	135910508	Missense_Mutation	rs139744161	R653H	0.86
OV	chrX	135908528	Missense_Mutation	rs782116354	R451Q	0.22
OV	chrX	135911203	Missense_Mutation	NA	T673S	0.22
PRAD	chrX	135908509	Silent	NA	R445R	0.65
PRAD	chrX	135906422	Missense_Mutation	NA	T203P	0.31
READ	chrX	135912891	Missense_Mutation	NA	K903N	0.51
READ	chrX	135907821	Missense_Mutation	novel	A380V	0.84
READ	chrX	135908863	Splice_Site	novel	X481_splice	0.85
READ	chrX	135910439	Missense_Mutation	rs782604698	R630H	0.86
READ	chrX	135906480	Missense_Mutation	NA	L222S	0.12
READ	chrX	135911263	Missense_Mutation	NA	S693P	0.14
READ	chrX	135911879	Missense_Mutation	NA	S816F	0.15
SKCM	chrX	135906963	Missense_Mutation	NA	M258I	0.25
SKCM	chrX	135912389	Missense_Mutation	NA	E864K	0.74	INT_SG_DDX_CT_C
SKCM	chrX	135910053	Missense_Mutation	rs143132398	H583Y	0.18
SKCM	chrX	135911309	Missense_Mutation	NA	S708L	0.87
SKCM	chrX	135908923	Missense_Mutation	NA	D501N	0.43
SKCM	chrX	135910056	Missense_Mutation	NA	E584K	0.23
SKCM	chrX	135908164	Missense_Mutation	rs782046608	A412V	0.34
SKCM	chrX	135905306	Missense_Mutation	NA	R123Q	0.13
SKCM	chrX	135908194	Missense_Mutation	novel	G422E	0.92
SKCM	chrX	135910532	Missense_Mutation	NA	S661L	0.62
SKCM	chrX	135905306	Missense_Mutation	NA	R123Q	0.14
SKCM	chrX	135908528	Missense_Mutation	rs782116354	R451Q	0.52
SKCM	chrX	135908985	Silent	NA	S521S	0.65
SKCM	chrX	135910429	Missense_Mutation	NA	H627Y	0.35
SKCM	chrX	135908222	Silent	NA	R431R	0.84
SKCM	chrX	135912814	Missense_Mutation	NA	L878I	0.47	INT_SG_DDX_CT_C
SKCM	chrX	135909677	Missense_Mutation	NA	E541K	0.33
SKCM	chrX	135908493	Silent	NA	H439H	0.68
SKCM	chrX	135911326	Missense_Mutation	NA	D714N	0.78
SKCM	chrX	135910163	Silent	novel	R619R	0.58
SKCM	chrX	135910164	Missense_Mutation	NA	D620N	0.7
SKCM	chrX	135904566	Missense_Mutation	NA	P104S	0.17
SKCM	chrX	135906112	Silent	NA	G181G	0.18
SKCM	chrX	135911611	Missense_Mutation	NA	E727K	0.12
SKCM	chrX	135908528	Missense_Mutation	rs782116354	R451Q	0.66
SKCM	chrX	135911214	Silent	novel	V676V	0.42
SKCM	chrX	135907811	Missense_Mutation	novel	D377N	0.96
SKCM	chrX	135906977	Missense_Mutation	NA	P263L	0.59
SKCM	chrX	135906498	Missense_Mutation	rs782626692	R228Q	0.72
SKCM	chrX	135910113	Missense_Mutation	NA	P603S	0.83
SKCM	chrX	135907835	Missense_Mutation	novel	D385N	0.86
SKCM	chrX	135906491	Nonsense_Mutation	NA	R226*	0.45
SKCM	chrX	135912337	Silent	NA	F846F	0.2
SKCM	chrX	135908866	Missense_Mutation	novel	A482T	0.39
SKCM	chrX	135908867	Missense_Mutation	novel	A482D	0.38
SKCM	chrX	135911611	Missense_Mutation	NA	E727K	0.42
SKCM	chrX	135907030	Missense_Mutation	novel	G281R	0.47
SKCM	chrX	135901676	Silent	novel	L69L	0.75
SKCM	chrX	135901644	Missense_Mutation	NA	S58L	0.46
SKCM	chrX	135908148	Missense_Mutation	NA	D407N	0.77
SKCM	chrX	135911297	Missense_Mutation	NA	G704E	0.1
SKCM	chrX	135908611	Missense_Mutation	novel	D479N	0.74
SKCM	chrX	135908582	Missense_Mutation	novel	G469E	0.28
SKCM	chrX	135906955	Missense_Mutation	NA	E256K	0.9
SKCM	chrX	135912320	Splice_Site	NA	X841_splice	0.97
SKCM	chrX	135906964	Missense_Mutation	novel	E259K	0.46
SKCM	chrX	135910535	Missense_Mutation	novel	S662F	0.2
SKCM	chrX	135910536	Silent	novel	S662S	0.19
SKCM	chrX	135905369	Missense_Mutation	novel	P144L	0.3
SKCM	chrX	135908535	Silent	NA	Q453Q	0.69
STAD	chrX	135911891	Frame_Shift_Ins	novel	*K822Efs3**	0.26	INT_SG_DDX_CT_C
STAD	chrX	135901596	Missense_Mutation	NA	G42E	0.09
STAD	chrX	135910044	Missense_Mutation	NA	H580N	0.36
STAD	chrX	135906989	Missense_Mutation	NA	N267T	0.3
STAD	chrX	135908931	Silent	NA	V503V	0.77
STAD	chrX	135911683	Missense_Mutation	NA	T751A	0.76
STAD	chrX	135911938	Nonsense_Mutation	rs782625354	R836*	0.72	INT_SG_DDX_CT_C
STAD	chrX	135911234	Missense_Mutation	novel	N683T	0.82
STAD	chrX	135912955	3'UTR	novel		0.22
STAD	chrX	135912802	Frame_Shift_Del	NA	*V876Lfs3**	0.18	INT_SG_DDX_CT_C
STAD	chrX	135911749	Missense_Mutation	novel	D773H	0.37
STAD	chrX	135904514	Silent	NA	I86I	0.63
STAD	chrX	135912897	Silent	NA	*905*	0.26
STAD	chrX	135907430	Missense_Mutation	rs367622228	P332L	0.15
STAD	chrX	135907431	Silent	NA	P332P	0.47
STAD	chrX	135907364	Missense_Mutation	rs782012489	P310L	0.07
STAD	chrX	135904487	Silent	novel	V77V	0.36
STAD	chrX	135908485	Missense_Mutation	rs782285077	V437I	0.33
STAD	chrX	135911670	Missense_Mutation	novel	E746D	0.67
STAD	chrX	135901622	Missense_Mutation	NA	R51G	0.1
STAD	chrX	135905329	Missense_Mutation	NA	A131T	0.21
STAD	chrX	135908947	Missense_Mutation	NA	P509T	0.11
STAD	chrX	135911895	Frame_Shift_Del	NA	*I823Lfs5**	0.4	INT_SG_DDX_CT_C
STAD	chrX	135906450	Frame_Shift_Del	novel	*N213Mfs11**	0.22
TGCT	chrX	135911670	Missense_Mutation	novel	E746D	0.19
UCEC	chrX	135909638	Splice_Site	NA	X528_splice	0.22
UCEC	chrX	135906492	Missense_Mutation	NA	R226L	0.18
UCEC	chrX	135906429	Missense_Mutation	NA	N205S	0.33
UCEC	chrX	135908887	Missense_Mutation	NA	R489C	0.25
UCEC	chrX	135913039	3'UTR	novel		0.27
UCEC	chrX	135908102	Silent	novel	I391I	0.42
UCEC	chrX	135906135	Missense_Mutation	NA	P189H	0.34
UCEC	chrX	135907012	Missense_Mutation	NA	G275W	0.32
UCEC	chrX	135896246	Nonsense_Mutation	novel	Q2*	0.2
UCEC	chrX	135904495	Missense_Mutation	novel	S80N	0.49
UCEC	chrX	135907360	Nonsense_Mutation	novel	Q309*	0.08
UCEC	chrX	135907748	Nonsense_Mutation	novel	Q356*	0.36
UCEC	chrX	135907759	Silent	novel	P359P	0.45
UCEC	chrX	135907723	Silent	novel	V347V	0.37
UCEC	chrX	135913012	3'UTR	novel		0.27
UCEC	chrX	135908614	Missense_Mutation	novel	L480M	0.41
UCEC	chrX	135906089	Missense_Mutation	rs782279412	V174I	0.48
UCEC	chrX	135912334	Missense_Mutation	novel	I845M	0.18	INT_SG_DDX_CT_C
UCEC	chrX	135909647	Missense_Mutation	rs782691323	V531I	0.17
UCEC	chrX	135910131	Missense_Mutation	NA	A609S	0.29
UCEC	chrX	135912961	3'UTR	novel		0.3
UCEC	chrX	135904529	Silent	rs782516735	P91P	0.42
UCEC	chrX	135905275	Missense_Mutation	NA	R113C	0.26
UCEC	chrX	135912384	Missense_Mutation	NA	F862C	0.15	INT_SG_DDX_CT_C
UCEC	chrX	135906053	Nonsense_Mutation	novel	E162*	0.13
UCEC	chrX	135901633	Missense_Mutation	NA	K54N	0.44
UCEC	chrX	135911200	Missense_Mutation	NA	A672T	0.52
UCEC	chrX	135912330	Missense_Mutation	NA	R844I	0.22	INT_SG_DDX_CT_C
UCEC	chrX	135911938	Nonsense_Mutation	rs782625354	R836*	0.42	INT_SG_DDX_CT_C
UCEC	chrX	135908928	Missense_Mutation	novel	K502N	0.35
UCEC	chrX	135912991	3'UTR	novel		0.5
UCEC	chrX	135905263	Missense_Mutation	NA	A109T	0.15
UCEC	chrX	135906149	Missense_Mutation	novel	S194R	0.34
UCEC	chrX	135908156	Silent	novel	V409V	0.23
UCEC	chrX	135911199	Silent	novel	T671T	0.48
UCEC	chrX	135910088	Silent	rs781977573	S594S	0.33
UCEC	chrX	135910544	Missense_Mutation	novel	T665I	0.26
UCEC	chrX	135907758	Missense_Mutation	novel	P359R	0.52
UCEC	chrX	135911601	Silent	novel	I723I	0.37
UCEC	chrX	135912844	Nonsense_Mutation	novel	E888*	0.34
UCEC	chrX	135909725	Nonsense_Mutation	novel	G557*	0.56
UCEC	chrX	135908527	Nonsense_Mutation	rs781867792	R451*	0.42
UCEC	chrX	135908971	Missense_Mutation	novel	G517C	0.51
UCEC	chrX	135910457	Missense_Mutation	novel	N636S	0.4
UCEC	chrX	135913042	3'UTR	novel		0.71
UCEC	chrX	135906163	Splice_Region	rs782788019	L198L	0.63
UCEC	chrX	135912971	3'UTR	novel		0.31
UCEC	chrX	135908557	Missense_Mutation	novel	L461I	0.46
UCEC	chrX	135910519	Missense_Mutation	novel	A657S	0.39
UCEC	chrX	135908124	Missense_Mutation	novel	K399E	0.46
UCEC	chrX	135906090	Missense_Mutation	NA	V174G	0.22
UCEC	chrX	135906161	Missense_Mutation	novel	L198I	0.15
UCEC	chrX	135906429	Missense_Mutation	novel	N205T	0.21
UCEC	chrX	135908946	Silent	novel	A508A	0.15
UCEC	chrX	135910089	Missense_Mutation	rs371669134	D595N	0.26
UCEC	chrX	135911717	Missense_Mutation	novel	S762Y	0.23
UCEC	chrX	135910499	Missense_Mutation	novel	P650Q	0.29
UCEC	chrX	135905278	Missense_Mutation	novel	E114K	0.24
UCEC	chrX	135908927	Missense_Mutation	novel	K502T	0.36
UCEC	chrX	135911595	Silent	rs782514048	H721H	0.37
UCEC	chrX	135908191	Missense_Mutation	novel	A421V	0.14
UCEC	chrX	135911317	Missense_Mutation	novel	S711G	0.09
UCEC	chrX	135911938	Nonsense_Mutation	rs782625354	R836*	0.34	INT_SG_DDX_CT_C
UCEC	chrX	135912996	3'UTR	novel		0.5
UCEC	chrX	135909768	Missense_Mutation	NA	T571I	0.41
UCEC	chrX	135908156	Silent	novel	V409V	0.13
UCEC	chrX	135911762	Missense_Mutation	novel	Y777C	0.18
UCEC	chrX	135896243	Translation_Start_Site	novel	M1?	0.2
UCEC	chrX	135907766	Missense_Mutation	rs782737930	A362T	0.13
UCEC	chrX	135908523	Silent	novel	G449G	0.05
UCEC	chrX	135910054	Missense_Mutation	rs782574608	H583R	0.44
UCEC	chrX	135910138	Missense_Mutation	novel	T611I	0.33
UCEC	chrX	135911796	Frame_Shift_Ins	novel	*N790Kfs8**	0.31
UCEC	chrX	135908131	Missense_Mutation	NA	N401S	0.41
UCEC	chrX	135901615	Missense_Mutation	novel	K48N	0.47
UCEC	chrX	135908887	Missense_Mutation	NA	R489C	0.36
UCEC	chrX	135910089	Missense_Mutation	rs371669134	D595N	0.49
UCEC	chrX	135912869	Missense_Mutation	NA	R896I	0.48
UCEC	chrX	135912991	3'UTR	novel		0.11
UCEC	chrX	135910097	Frame_Shift_Ins	novel	*S599Lfs9**	0.35
UCEC	chrX	135911894	Missense_Mutation	NA	K821T	0.29
UCEC	chrX	135901569	Missense_Mutation	novel	S33I	0.45
UCEC	chrX	135909003	Splice_Region	NA	L527L	0.04
UCEC	chrX	135904544	Silent	NA	V96V	0.42
UCEC	chrX	135912887	Missense_Mutation	novel	R902I	0.32
UCEC	chrX	135912836	Missense_Mutation	rs782694777	A885V	0.44
UCEC	chrX	135907019	Missense_Mutation	rs781819525	I277T	0.38
UCEC	chrX	135911199	Silent	novel	T671T	0.39
UCEC	chrX	135909759	Missense_Mutation	novel	A568V	0.35
UCEC	chrX	135911938	Nonsense_Mutation	rs782625354	R836*	0.41	INT_SG_DDX_CT_C
UCEC	chrX	135912967	3'UTR	novel		0.5
UCEC	chrX	135906501	Missense_Mutation	rs781926163	R229H	0.32
UCEC	chrX	135910088	Silent	rs781977573	S594S	0.73
UCS	chrX	135909762	Missense_Mutation	novel	M569T	0.13

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
DLBC	AMP	0.0833	0.24013
KIRC	AMP	0.0303	0.12739
READ	AMP	0.1394	0.14805
TGCT	DEL	0.0667	0.08422
THCA	DEL	0	0.21991
UCS	DEL	0.3036	0.063955

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0016	Kaplan-Meier Survival Analysis
STAD	0.0086	Kaplan-Meier Survival Analysis
MESO	0.037	Kaplan-Meier Survival Analysis
LAML	0.00021	Kaplan-Meier Survival Analysis
LGG	0.00038	Kaplan-Meier Survival Analysis
OV	0.022	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742