EuRBPDB

Description

Ensembl ID: ENSG00000181789 (Gene tree)
Gene ID: 22820
Gene Symbol: COPG1
Alias: COPG
Full Name: coatomer protein complex subunit gamma 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 28,199 bases
Position: chr3:129,249,575-129,277,773
Accession: 2236
RBP type: non-canonical RBP
Summary: (Coatomer Protein Complex Subunit Gamma 1) is a Protein Coding gene. Among its related pathways are Transport to the Golgi and subsequent modification and Delta508-CFTR traffic / ER-to-Golgi in CF. Gene Ontology (GO) annotations related to this gene include binding and structural molecule activity. An important paralog of this gene is COPG2.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000515725	COPG1-210	3231	-	-	- (aa)	-	-
ENST00000504350	COPG1-202	672	-	ENSP00000426457	49 (aa)	-	D6RG17
ENST00000509208	COPG1-204	472	-	-	- (aa)	-	-
ENST00000513965	COPG1-208	730	-	-	- (aa)	-	-
ENST00000512034	COPG1-206	398	-	-	- (aa)	-	-
ENST00000314797	COPG1-201	3078	-	ENSP00000325002	874 (aa)	-	Q9Y678
ENST00000514478	COPG1-209	734	-	ENSP00000420916	76 (aa)	-	H0Y8G2
ENST00000509889	COPG1-205	599	-	ENSP00000422478	188 (aa)	-	H0Y8X7
ENST00000504547	COPG1-203	586	-	-	- (aa)	-	-
ENST00000513410	COPG1-207	545	-	-	- (aa)	-	-

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000181789	Child Development Disorders, Pervasive	5.8000000E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000181789	rs6762578	3	129273204	?	Fat-free mass	30593698	[0.092-0.207] unit increase	0.14962	EFO_0004995
ENSG00000181789	rs6762578	3	129273204	?	Fat-free mass	30593698	[0.15-0.31] unit increase	0.22767	EFO_0004995
ENSG00000181789	rs6762578	3	129273204	?	Fat-free mass	30593698	[0.14-0.25] unit increase	0.19658	EFO_0004995

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000181789	COPG1	99	55.986	WBGene00011775	T14G10.5	99	55.986	Caenorhabditis_elegans
ENSG00000181789	COPG1	95	34.884	YNL287W		95	34.662	Saccharomyces_cerevisiae

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000139	Golgi membrane	21873635.	IBA	Component
GO:0000139	Golgi membrane	-	ISS	Component
GO:0000139	Golgi membrane	-	TAS	Component
GO:0005198	structural molecule activity	-	IEA	Function
GO:0005515	protein binding	14527956.19039328.25036637.	IPI	Function
GO:0005783	endoplasmic reticulum	21873635.	IBA	Component
GO:0005789	endoplasmic reticulum membrane	-	TAS	Component
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	21873635.	IBA	Component
GO:0005794	Golgi apparatus	21873635.	IBA	Component
GO:0005794	Golgi apparatus	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006886	intracellular protein transport	-	IEA	Process
GO:0006888	ER to Golgi vesicle-mediated transport	21873635.	IBA	Process
GO:0006888	ER to Golgi vesicle-mediated transport	-	TAS	Process
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	-	TAS	Process
GO:0006891	intra-Golgi vesicle-mediated transport	21873635.	IBA	Process
GO:0009306	protein secretion	21873635.	IBA	Process
GO:0016020	membrane	21873635.	IBA	Component
GO:0030126	COPI vesicle coat	21873635.	IBA	Component
GO:0030126	COPI vesicle coat	-	ISS	Component
GO:0030133	transport vesicle	-	TAS	Component
GO:0051683	establishment of Golgi localization	-	ISS	Process
GO:0072384	organelle transport along microtubule	21873635.	IBA	Process
GO:0072384	organelle transport along microtubule	-	ISS	Process