EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000182180 (Gene tree)
Gene ID: 51021
Gene Symbol: MRPS16
Alias: CGI-132
Full Name: mitochondrial ribosomal protein S16
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 3,851 bases
Position: chr10:73,248,843-73,252,693
Accession: 14048
RBP type: canonical RBP
Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S16P family. The encoded protein is one of the most highly conserved ribosomal proteins between mammalian and yeast mitochondria. Three pseudogenes (located at 8q21.3, 20q13.32, 22q12-q13.1) for this gene have been described. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000362031	Ribosomal_S16	PF00886.19	8.3e-23	1	1
ENSP00000362036	Ribosomal_S16	PF00886.19	9.1e-23	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000471251	MRPS16-203	658	-	-	- (aa)	-	-
ENST00000473427	MRPS16-204	612	-	-	- (aa)	-	-
ENST00000372945	MRPS16-202	2634	-	ENSP00000362036	137 (aa)	-	Q9Y3D3
ENST00000372940	MRPS16-201	866	-	ENSP00000362031	99 (aa)	-	A6ND22
ENST00000479005	MRPS16-205	2580	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000182180's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03010	Ribosome	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000182180's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000182180	MRPS16	94	67.368	ENSAPOG00000012117	mrps16	93	61.314	Acanthochromis_polyacanthus
ENSG00000182180	MRPS16	95	89.231	ENSAMEG00000016931	MRPS16	99	89.231	Ailuropoda_melanoleuca
ENSG00000182180	MRPS16	94	68.421	ENSACIG00000008004	mrps16	82	70.796	Amphilophus_citrinellus
ENSG00000182180	MRPS16	94	67.368	ENSAOCG00000006801	mrps16	93	62.774	Amphiprion_ocellaris
ENSG00000182180	MRPS16	94	66.316	ENSAPEG00000004562	mrps16	93	62.044	Amphiprion_percula
ENSG00000182180	MRPS16	94	65.263	ENSATEG00000024962	mrps16	86	66.387	Anabas_testudineus
ENSG00000182180	MRPS16	100	97.980	ENSANAG00000036208	MRPS16	100	97.980	Aotus_nancymaae
ENSG00000182180	MRPS16	94	67.368	ENSACLG00000016154	mrps16	81	69.369	Astatotilapia_calliptera
ENSG00000182180	MRPS16	94	69.892	ENSAMXG00000040279	mrps16	99	61.765	Astyanax_mexicanus
ENSG00000182180	MRPS16	95	69.149	ENSBTAG00000053412	-	100	68.182	Bos_taurus
ENSG00000182180	MRPS16	94	95.699	ENSBTAG00000000950	MRPS16	99	91.729	Bos_taurus
ENSG00000182180	MRPS16	80	49.398	WBGene00018961	mrps-16	87	42.969	Caenorhabditis_elegans
ENSG00000182180	MRPS16	100	97.080	ENSCJAG00000007538	MRPS16	100	97.080	Callithrix_jacchus
ENSG00000182180	MRPS16	99	61.481	ENSCAFG00000008928	-	99	61.481	Canis_familiaris
ENSG00000182180	MRPS16	99	88.148	ENSCAFG00000031286	-	68	88.148	Canis_familiaris
ENSG00000182180	MRPS16	97	85.714	ENSCAFG00020023773	-	99	85.714	Canis_lupus_dingo
ENSG00000182180	MRPS16	80	87.273	ENSCAFG00020025503	-	97	85.366	Canis_lupus_dingo
ENSG00000182180	MRPS16	94	70.213	ENSCHIG00000016255	-	88	60.145	Capra_hircus
ENSG00000182180	MRPS16	98	94.845	ENSTSYG00000034400	-	100	93.333	Carlito_syrichta
ENSG00000182180	MRPS16	98	70.149	ENSTSYG00000014457	-	100	70.149	Carlito_syrichta
ENSG00000182180	MRPS16	91	81.111	ENSTSYG00000036920	-	98	68.939	Carlito_syrichta
ENSG00000182180	MRPS16	91	84.444	ENSTSYG00000026797	-	95	70.992	Carlito_syrichta
ENSG00000182180	MRPS16	95	80.769	ENSCAPG00000015053	MRPS16	100	80.769	Cavia_aperea
ENSG00000182180	MRPS16	99	91.111	ENSCPOG00000025500	MRPS16	100	91.111	Cavia_porcellus
ENSG00000182180	MRPS16	100	95.960	ENSCCAG00000037051	MRPS16	100	95.960	Cebus_capucinus
ENSG00000182180	MRPS16	100	93.431	ENSCATG00000040457	MRPS16	100	93.431	Cercocebus_atys
ENSG00000182180	MRPS16	99	89.630	ENSCLAG00000010443	MRPS16	100	89.630	Chinchilla_lanigera
ENSG00000182180	MRPS16	100	93.431	ENSCSAG00000000413	-	100	93.431	Chlorocebus_sabaeus
ENSG00000182180	MRPS16	100	92.701	ENSCSAG00000018977	-	100	92.701	Chlorocebus_sabaeus
ENSG00000182180	MRPS16	100	92.701	ENSCSAG00000018976	-	100	92.701	Chlorocebus_sabaeus
ENSG00000182180	MRPS16	97	87.218	ENSCHOG00000012520	MRPS16	100	87.218	Choloepus_hoffmanni
ENSG00000182180	MRPS16	94	68.817	ENSCPBG00000022282	MRPS16	96	67.742	Chrysemys_picta_bellii
ENSG00000182180	MRPS16	77	57.895	ENSCING00000024826	-	66	52.632	Ciona_intestinalis
ENSG00000182180	MRPS16	86	52.941	ENSCSAVG00000006333	-	72	47.200	Ciona_savignyi
ENSG00000182180	MRPS16	100	94.891	ENSCANG00000010568	MRPS16	100	94.891	Colobus_angolensis_palliatus
ENSG00000182180	MRPS16	99	89.630	ENSCGRG00001023386	Mrps16	100	89.630	Cricetulus_griseus_chok1gshd
ENSG00000182180	MRPS16	99	89.630	ENSCGRG00000002182	Mrps16	100	89.630	Cricetulus_griseus_crigri
ENSG00000182180	MRPS16	94	66.316	ENSCSEG00000021662	mrps16	100	59.854	Cynoglossus_semilaevis
ENSG00000182180	MRPS16	94	64.211	ENSCVAG00000012001	mrps16	96	60.769	Cyprinodon_variegatus
ENSG00000182180	MRPS16	94	70.968	ENSDARG00000098972	mrps16	99	64.844	Danio_rerio
ENSG00000182180	MRPS16	94	93.548	ENSDNOG00000047675	MRPS16	100	89.781	Dasypus_novemcinctus
ENSG00000182180	MRPS16	87	77.907	ENSDORG00000023262	-	97	78.022	Dipodomys_ordii
ENSG00000182180	MRPS16	99	93.333	ENSDORG00000008275	-	100	93.333	Dipodomys_ordii
ENSG00000182180	MRPS16	87	47.059	FBgn0033907	mRpS16	84	47.059	Drosophila_melanogaster
ENSG00000182180	MRPS16	79	55.128	ENSEBUG00000001088	mrps16	85	58.000	Eptatretus_burgeri
ENSG00000182180	MRPS16	91	89.600	ENSEASG00005017192	MRPS16	95	89.600	Equus_asinus_asinus
ENSG00000182180	MRPS16	91	89.600	ENSECAG00000009146	MRPS16	95	89.600	Equus_caballus
ENSG00000182180	MRPS16	94	65.263	ENSELUG00000011609	mrps16	85	67.257	Esox_lucius
ENSG00000182180	MRPS16	99	91.111	ENSFCAG00000037310	MRPS16	100	91.111	Felis_catus
ENSG00000182180	MRPS16	99	56.618	ENSFALG00000009917	MRPS16	98	56.618	Ficedula_albicollis
ENSG00000182180	MRPS16	94	94.624	ENSFDAG00000014014	MRPS16	98	92.537	Fukomys_damarensis
ENSG00000182180	MRPS16	94	62.105	ENSFHEG00000022624	mrps16	99	55.882	Fundulus_heteroclitus
ENSG00000182180	MRPS16	94	66.316	ENSGMOG00000001558	mrps16	88	68.142	Gadus_morhua
ENSG00000182180	MRPS16	94	70.968	ENSGALG00000050621	MRPS16	96	65.441	Gallus_gallus
ENSG00000182180	MRPS16	94	65.263	ENSGAFG00000012456	mrps16	99	59.559	Gambusia_affinis
ENSG00000182180	MRPS16	100	60.432	ENSGACG00000001715	mrps16	100	60.432	Gasterosteus_aculeatus
ENSG00000182180	MRPS16	95	45.385	ENSGAGG00000005030	-	97	45.385	Gopherus_agassizii
ENSG00000182180	MRPS16	94	74.194	ENSGAGG00000000097	-	87	71.774	Gopherus_agassizii
ENSG00000182180	MRPS16	100	100.000	ENSGGOG00000015055	MRPS16	100	100.000	Gorilla_gorilla
ENSG00000182180	MRPS16	94	67.368	ENSHBUG00000015492	mrps16	82	70.270	Haplochromis_burtoni
ENSG00000182180	MRPS16	99	90.370	ENSHGLG00000012797	MRPS16	100	90.370	Heterocephalus_glaber_female
ENSG00000182180	MRPS16	99	90.370	ENSHGLG00100007890	MRPS16	100	90.370	Heterocephalus_glaber_male
ENSG00000182180	MRPS16	94	63.158	ENSHCOG00000020173	mrps16	91	64.407	Hippocampus_comes
ENSG00000182180	MRPS16	94	70.968	ENSIPUG00000003397	mrps16	99	63.910	Ictalurus_punctatus
ENSG00000182180	MRPS16	99	91.111	ENSSTOG00000027184	MRPS16	100	91.111	Ictidomys_tridecemlineatus
ENSG00000182180	MRPS16	99	91.111	ENSJJAG00000023255	Mrps16	100	91.791	Jaculus_jaculus
ENSG00000182180	MRPS16	94	64.211	ENSKMAG00000009755	mrps16	97	57.971	Kryptolebias_marmoratus
ENSG00000182180	MRPS16	94	62.105	ENSLBEG00000024661	mrps16	99	56.618	Labrus_bergylta
ENSG00000182180	MRPS16	94	73.118	ENSLACG00000019160	MRPS16	96	67.910	Latimeria_chalumnae
ENSG00000182180	MRPS16	94	68.817	ENSLOCG00000003927	mrps16	84	70.435	Lepisosteus_oculatus
ENSG00000182180	MRPS16	95	84.615	ENSLAFG00000023124	MRPS16	99	84.615	Loxodonta_africana
ENSG00000182180	MRPS16	100	93.431	ENSMFAG00000032103	MRPS16	100	93.431	Macaca_fascicularis
ENSG00000182180	MRPS16	100	90.909	ENSMMUG00000011284	MRPS16	100	90.909	Macaca_mulatta
ENSG00000182180	MRPS16	100	93.431	ENSMNEG00000041963	MRPS16	100	93.431	Macaca_nemestrina
ENSG00000182180	MRPS16	100	93.431	ENSMLEG00000044343	MRPS16	100	93.431	Mandrillus_leucophaeus
ENSG00000182180	MRPS16	94	67.368	ENSMAMG00000015181	mrps16	100	59.712	Mastacembelus_armatus
ENSG00000182180	MRPS16	93	70.652	ENSMGAG00000000893	MRPS16	85	70.940	Meleagris_gallopavo
ENSG00000182180	MRPS16	94	96.774	ENSMAUG00000010491	Mrps16	100	91.111	Mesocricetus_auratus
ENSG00000182180	MRPS16	99	89.630	ENSMICG00000042573	MRPS16	100	89.630	Microcebus_murinus
ENSG00000182180	MRPS16	94	94.624	ENSMOCG00000006927	Mrps16	100	88.148	Microtus_ochrogaster
ENSG00000182180	MRPS16	94	60.000	ENSMMOG00000010770	mrps16	99	56.618	Mola_mola
ENSG00000182180	MRPS16	94	75.269	ENSMODG00000000168	MRPS16	96	73.077	Monodelphis_domestica
ENSG00000182180	MRPS16	94	62.105	ENSMALG00000007222	mrps16	81	65.487	Monopterus_albus
ENSG00000182180	MRPS16	99	91.852	MGP_CAROLIEiJ_G0018987	Mrps16	100	91.852	Mus_caroli
ENSG00000182180	MRPS16	99	91.111	ENSMUSG00000049960	Mrps16	100	91.111	Mus_musculus
ENSG00000182180	MRPS16	94	96.774	MGP_PahariEiJ_G0030001	Mrps16	100	89.630	Mus_pahari
ENSG00000182180	MRPS16	94	96.774	MGP_SPRETEiJ_G0019865	Mrps16	100	91.111	Mus_spretus
ENSG00000182180	MRPS16	97	91.729	ENSMPUG00000003777	MRPS16	86	91.729	Mustela_putorius_furo
ENSG00000182180	MRPS16	94	87.097	ENSMLUG00000022951	MRPS16	100	86.667	Myotis_lucifugus
ENSG00000182180	MRPS16	98	90.370	ENSNGAG00000019881	Mrps16	99	90.370	Nannospalax_galili
ENSG00000182180	MRPS16	94	67.368	ENSNBRG00000020914	mrps16	81	70.270	Neolamprologus_brichardi
ENSG00000182180	MRPS16	100	98.540	ENSNLEG00000018904	-	100	98.540	Nomascus_leucogenys
ENSG00000182180	MRPS16	100	77.372	ENSNLEG00000029922	-	98	77.372	Nomascus_leucogenys
ENSG00000182180	MRPS16	100	100.000	ENSNLEG00000016597	-	100	100.000	Nomascus_leucogenys
ENSG00000182180	MRPS16	89	81.818	ENSMEUG00000008644	MRPS16	99	77.686	Notamacropus_eugenii
ENSG00000182180	MRPS16	94	94.624	ENSOPRG00000018616	MRPS16	100	90.076	Ochotona_princeps
ENSG00000182180	MRPS16	99	90.370	ENSODEG00000019541	-	100	90.370	Octodon_degus
ENSG00000182180	MRPS16	75	91.892	ENSODEG00000013980	-	93	91.892	Octodon_degus
ENSG00000182180	MRPS16	91	67.391	ENSONIG00000014282	mrps16	95	61.719	Oreochromis_niloticus
ENSG00000182180	MRPS16	100	72.993	ENSOANG00000012378	MRPS16	100	72.993	Ornithorhynchus_anatinus
ENSG00000182180	MRPS16	94	92.473	ENSOCUG00000024223	-	100	88.148	Oryctolagus_cuniculus
ENSG00000182180	MRPS16	94	97.849	ENSOCUG00000023231	-	100	91.852	Oryctolagus_cuniculus
ENSG00000182180	MRPS16	94	65.263	ENSORLG00000022084	mrps16	100	59.712	Oryzias_latipes
ENSG00000182180	MRPS16	94	65.263	ENSORLG00020019793	mrps16	100	58.993	Oryzias_latipes_hni
ENSG00000182180	MRPS16	94	65.263	ENSORLG00015015664	mrps16	94	61.654	Oryzias_latipes_hsok
ENSG00000182180	MRPS16	94	65.263	ENSOMEG00000021490	mrps16	100	58.273	Oryzias_melastigma
ENSG00000182180	MRPS16	99	91.912	ENSOGAG00000033867	MRPS16	99	91.912	Otolemur_garnettii
ENSG00000182180	MRPS16	94	95.699	ENSOARG00000007548	MRPS16	86	92.481	Ovis_aries
ENSG00000182180	MRPS16	100	100.000	ENSPPAG00000009406	MRPS16	100	100.000	Pan_paniscus
ENSG00000182180	MRPS16	99	91.111	ENSPPRG00000024759	MRPS16	100	91.111	Panthera_pardus
ENSG00000182180	MRPS16	99	91.111	ENSPTIG00000021428	MRPS16	100	91.111	Panthera_tigris_altaica
ENSG00000182180	MRPS16	100	100.000	ENSPTRG00000002627	MRPS16	100	100.000	Pan_troglodytes
ENSG00000182180	MRPS16	94	82.796	ENSPTRG00000044912	-	100	83.636	Pan_troglodytes
ENSG00000182180	MRPS16	100	92.701	ENSPANG00000022374	MRPS16	100	92.701	Papio_anubis
ENSG00000182180	MRPS16	94	67.742	ENSPKIG00000013816	mrps16	91	62.406	Paramormyrops_kingsleyae
ENSG00000182180	MRPS16	94	67.742	ENSPSIG00000005589	MRPS16	87	66.935	Pelodiscus_sinensis
ENSG00000182180	MRPS16	94	65.263	ENSPMGG00000013450	mrps16	100	60.769	Periophthalmus_magnuspinnatus
ENSG00000182180	MRPS16	94	96.774	ENSPEMG00000021378	Mrps16	100	89.630	Peromyscus_maniculatus_bairdii
ENSG00000182180	MRPS16	94	79.570	ENSPCIG00000015166	MRPS16	100	74.242	Phascolarctos_cinereus
ENSG00000182180	MRPS16	94	66.316	ENSPFOG00000014130	mrps16	100	57.554	Poecilia_formosa
ENSG00000182180	MRPS16	94	66.316	ENSPLAG00000018686	mrps16	100	57.554	Poecilia_latipinna
ENSG00000182180	MRPS16	94	66.316	ENSPMEG00000009648	mrps16	100	57.554	Poecilia_mexicana
ENSG00000182180	MRPS16	94	65.263	ENSPREG00000005800	mrps16	99	58.824	Poecilia_reticulata
ENSG00000182180	MRPS16	99	89.630	ENSPCOG00000009898	MRPS16	100	89.630	Propithecus_coquereli
ENSG00000182180	MRPS16	97	89.474	ENSPVAG00000012996	MRPS16	100	89.474	Pteropus_vampyrus
ENSG00000182180	MRPS16	94	67.368	ENSPNYG00000018439	mrps16	82	70.270	Pundamilia_nyererei
ENSG00000182180	MRPS16	94	72.043	ENSPNAG00000027291	mrps16	99	66.165	Pygocentrus_nattereri
ENSG00000182180	MRPS16	99	91.111	ENSRNOG00000006898	Mrps16	100	91.111	Rattus_norvegicus
ENSG00000182180	MRPS16	100	95.620	ENSRBIG00000037015	MRPS16	100	95.620	Rhinopithecus_bieti
ENSG00000182180	MRPS16	100	95.620	ENSRROG00000040939	MRPS16	100	95.620	Rhinopithecus_roxellana
ENSG00000182180	MRPS16	100	97.980	ENSSBOG00000016492	MRPS16	100	97.980	Saimiri_boliviensis_boliviensis
ENSG00000182180	MRPS16	94	72.043	ENSSHAG00000003006	MRPS16	98	69.697	Sarcophilus_harrisii
ENSG00000182180	MRPS16	94	68.817	ENSSFOG00015007264	mrps16	94	62.406	Scleropages_formosus
ENSG00000182180	MRPS16	100	60.432	ENSSMAG00000014748	mrps16	94	60.432	Scophthalmus_maximus
ENSG00000182180	MRPS16	94	66.316	ENSSDUG00000015177	mrps16	97	62.687	Seriola_dumerili
ENSG00000182180	MRPS16	94	66.316	ENSSLDG00000004507	mrps16	97	62.687	Seriola_lalandi_dorsalis
ENSG00000182180	MRPS16	97	61.765	ENSSPUG00000012312	MRPS16	99	61.765	Sphenodon_punctatus
ENSG00000182180	MRPS16	94	67.368	ENSSPAG00000007520	mrps16	95	63.077	Stegastes_partitus
ENSG00000182180	MRPS16	94	65.263	ENSTRUG00000021325	mrps16	97	65.873	Takifugu_rubripes
ENSG00000182180	MRPS16	94	65.263	ENSTNIG00000014796	MRPS16	99	59.420	Tetraodon_nigroviridis
ENSG00000182180	MRPS16	94	65.263	ENSTNIG00000006736	mrps16	99	59.420	Tetraodon_nigroviridis
ENSG00000182180	MRPS16	93	92.188	ENSTTRG00000000825	MRPS16	100	92.188	Tursiops_truncatus
ENSG00000182180	MRPS16	99	88.889	ENSUAMG00000005153	MRPS16	100	88.889	Ursus_americanus
ENSG00000182180	MRPS16	99	88.889	ENSUMAG00000009089	MRPS16	100	88.889	Ursus_maritimus
ENSG00000182180	MRPS16	93	92.913	ENSVPAG00000007263	MRPS16	99	92.913	Vicugna_pacos
ENSG00000182180	MRPS16	97	85.714	ENSVVUG00000022733	-	99	85.714	Vulpes_vulpes
ENSG00000182180	MRPS16	91	78.889	ENSVVUG00000005415	-	88	80.000	Vulpes_vulpes
ENSG00000182180	MRPS16	94	68.817	ENSXETG00000001399	mrps16	83	69.231	Xenopus_tropicalis
ENSG00000182180	MRPS16	83	66.667	ENSXCOG00000008280	mrps16	96	59.350	Xiphophorus_couchianus
ENSG00000182180	MRPS16	94	66.316	ENSXMAG00000000052	mrps16	100	59.701	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003735	structural constituent of ribosome	21873635.	IBA	Function
GO:0003735	structural constituent of ribosome	11402041.	ISS	Function
GO:0003735	structural constituent of ribosome	11279123.	NAS	Function
GO:0005515	protein binding	19945174.	IPI	Function
GO:0005739	mitochondrion	-	IDA	Component
GO:0005743	mitochondrial inner membrane	-	TAS	Component
GO:0005763	mitochondrial small ribosomal subunit	21873635.	IBA	Component
GO:0005763	mitochondrial small ribosomal subunit	11279123.25838379.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006412	translation	11279123.	NAS	Process
GO:0032543	mitochondrial translation	11402041.	ISS	Process
GO:0070125	mitochondrial translational elongation	-	TAS	Process
GO:0070126	mitochondrial translational termination	-	TAS	Process