EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000183617 (Gene tree)
Gene ID: 116541
Gene Symbol: MRPL54
Alias: N
Full Name: mitochondrial ribosomal protein L54
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 5,912 bases
Position: chr19:3,762,664-3,768,575
Accession: 16685
RBP type: canonical RBP
Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000331849	Ribosomal_L37	PF08561.10	2.4e-07	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000330133	MRPL54-201	626	-	ENSP00000331849	138 (aa)	-	Q6P161
ENST00000589174	MRPL54-202	491	-	ENSP00000467023	76 (aa)	-	K7ENN2

Gene Model

Click here to download ENSG00000183617's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000183617's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000183617	MRPL54	97	50.746	ENSAPOG00000022643	mrpl54	95	50.746	Acanthochromis_polyacanthus
ENSG00000183617	MRPL54	100	75.362	ENSAMEG00000005908	MRPL54	100	75.362	Ailuropoda_melanoleuca
ENSG00000183617	MRPL54	64	64.773	ENSACIG00000006438	mrpl54	73	63.462	Amphilophus_citrinellus
ENSG00000183617	MRPL54	62	62.353	ENSAOCG00000006430	mrpl54	95	50.000	Amphiprion_ocellaris
ENSG00000183617	MRPL54	62	62.353	ENSAPEG00000023406	mrpl54	95	50.000	Amphiprion_percula
ENSG00000183617	MRPL54	62	58.824	ENSATEG00000004969	mrpl54	73	58.654	Anabas_testudineus
ENSG00000183617	MRPL54	78	62.617	ENSACAG00000017747	-	97	62.617	Anolis_carolinensis
ENSG00000183617	MRPL54	100	84.058	ENSANAG00000028692	MRPL54	100	84.058	Aotus_nancymaae
ENSG00000183617	MRPL54	64	61.364	ENSACLG00000001877	mrpl54	73	60.577	Astatotilapia_calliptera
ENSG00000183617	MRPL54	59	63.415	ENSAMXG00000018143	mrpl54	77	55.856	Astyanax_mexicanus
ENSG00000183617	MRPL54	100	75.362	ENSBTAG00000008396	MRPL54	100	75.362	Bos_taurus
ENSG00000183617	MRPL54	55	43.210	WBGene00009128	mrpl-54	71	38.000	Caenorhabditis_elegans
ENSG00000183617	MRPL54	100	84.058	ENSCJAG00000014998	MRPL54	100	84.058	Callithrix_jacchus
ENSG00000183617	MRPL54	100	78.261	ENSCAFG00000019192	MRPL54	100	78.261	Canis_familiaris
ENSG00000183617	MRPL54	100	78.261	ENSCAFG00020018333	MRPL54	100	78.261	Canis_lupus_dingo
ENSG00000183617	MRPL54	100	76.087	ENSCHIG00000026538	MRPL54	100	76.087	Capra_hircus
ENSG00000183617	MRPL54	69	82.105	ENSCAPG00000012166	MRPL54	100	82.105	Cavia_aperea
ENSG00000183617	MRPL54	100	77.536	ENSCPOG00000031082	MRPL54	100	77.536	Cavia_porcellus
ENSG00000183617	MRPL54	100	81.159	ENSCCAG00000000138	MRPL54	100	81.159	Cebus_capucinus
ENSG00000183617	MRPL54	100	86.957	ENSCATG00000014066	MRPL54	100	86.957	Cercocebus_atys
ENSG00000183617	MRPL54	100	69.565	ENSCLAG00000007908	MRPL54	100	69.565	Chinchilla_lanigera
ENSG00000183617	MRPL54	100	88.406	ENSCSAG00000010950	MRPL54	100	88.406	Chlorocebus_sabaeus
ENSG00000183617	MRPL54	88	57.724	ENSCPBG00000017103	MRPL54	69	57.724	Chrysemys_picta_bellii
ENSG00000183617	MRPL54	78	39.252	ENSCING00000019896	-	75	39.252	Ciona_intestinalis
ENSG00000183617	MRPL54	77	38.318	ENSCSAVG00000009604	-	73	38.318	Ciona_savignyi
ENSG00000183617	MRPL54	100	87.681	ENSCANG00000027841	MRPL54	100	87.681	Colobus_angolensis_palliatus
ENSG00000183617	MRPL54	100	73.913	ENSCGRG00001019482	Mrpl54	100	73.913	Cricetulus_griseus_chok1gshd
ENSG00000183617	MRPL54	100	73.913	ENSCGRG00000010923	Mrpl54	100	73.913	Cricetulus_griseus_crigri
ENSG00000183617	MRPL54	62	67.059	ENSCSEG00000019883	mrpl54	71	62.727	Cynoglossus_semilaevis
ENSG00000183617	MRPL54	75	61.538	ENSCVAG00000002210	mrpl54	72	61.538	Cyprinodon_variegatus
ENSG00000183617	MRPL54	78	60.748	ENSDARG00000071468	mrpl54	77	60.748	Danio_rerio
ENSG00000183617	MRPL54	99	75.000	ENSDNOG00000007387	MRPL54	99	77.206	Dasypus_novemcinctus
ENSG00000183617	MRPL54	100	73.913	ENSDORG00000005326	Mrpl54	100	74.638	Dipodomys_ordii
ENSG00000183617	MRPL54	57	48.718	FBgn0034579	mRpL54	83	45.455	Drosophila_melanogaster
ENSG00000183617	MRPL54	97	75.373	ENSETEG00000017500	MRPL54	100	75.373	Echinops_telfairi
ENSG00000183617	MRPL54	63	52.874	ENSEBUG00000003179	mrpl54	75	52.874	Eptatretus_burgeri
ENSG00000183617	MRPL54	100	75.362	ENSEASG00005022283	MRPL54	100	75.362	Equus_asinus_asinus
ENSG00000183617	MRPL54	100	77.536	ENSECAG00000001515	MRPL54	100	77.536	Equus_caballus
ENSG00000183617	MRPL54	94	48.462	ENSELUG00000022358	mrpl54	88	51.538	Esox_lucius
ENSG00000183617	MRPL54	100	77.536	ENSFCAG00000007144	MRPL54	100	77.536	Felis_catus
ENSG00000183617	MRPL54	70	65.979	ENSFALG00000011660	MRPL54	89	65.979	Ficedula_albicollis
ENSG00000183617	MRPL54	100	70.213	ENSFDAG00000020803	MRPL54	100	70.213	Fukomys_damarensis
ENSG00000183617	MRPL54	62	63.529	ENSGALG00000027611	MRPL54	86	58.879	Gallus_gallus
ENSG00000183617	MRPL54	64	55.682	ENSGAFG00000016193	mrpl54	80	54.386	Gambusia_affinis
ENSG00000183617	MRPL54	99	50.000	ENSGAGG00000020238	MRPL54	98	50.000	Gopherus_agassizii
ENSG00000183617	MRPL54	100	97.826	ENSGGOG00000014722	MRPL54	100	97.826	Gorilla_gorilla
ENSG00000183617	MRPL54	62	63.529	ENSHBUG00000009028	mrpl54	60	60.577	Haplochromis_burtoni
ENSG00000183617	MRPL54	100	71.739	ENSHGLG00000006157	MRPL54	100	71.739	Heterocephalus_glaber_female
ENSG00000183617	MRPL54	100	71.739	ENSHGLG00100000788	MRPL54	100	71.739	Heterocephalus_glaber_male
ENSG00000183617	MRPL54	64	59.091	ENSHCOG00000000536	mrpl54	76	54.955	Hippocampus_comes
ENSG00000183617	MRPL54	64	61.364	ENSIPUG00000024854	mrpl54	95	52.593	Ictalurus_punctatus
ENSG00000183617	MRPL54	70	81.443	ENSSTOG00000022378	MRPL54	99	81.443	Ictidomys_tridecemlineatus
ENSG00000183617	MRPL54	100	70.290	ENSJJAG00000020405	Mrpl54	100	70.290	Jaculus_jaculus
ENSG00000183617	MRPL54	68	60.638	ENSKMAG00000022310	mrpl54	68	60.638	Kryptolebias_marmoratus
ENSG00000183617	MRPL54	75	62.500	ENSLBEG00000005935	mrpl54	74	62.500	Labrus_bergylta
ENSG00000183617	MRPL54	100	51.408	ENSLACG00000013912	MRPL54	100	51.408	Latimeria_chalumnae
ENSG00000183617	MRPL54	64	63.636	ENSLOCG00000003860	mrpl54	91	57.463	Lepisosteus_oculatus
ENSG00000183617	MRPL54	100	72.662	ENSLAFG00000029657	MRPL54	100	74.101	Loxodonta_africana
ENSG00000183617	MRPL54	100	87.681	ENSMFAG00000003311	MRPL54	100	87.681	Macaca_fascicularis
ENSG00000183617	MRPL54	100	87.681	ENSMMUG00000044080	MRPL54	100	87.681	Macaca_mulatta
ENSG00000183617	MRPL54	100	87.681	ENSMNEG00000039499	MRPL54	100	87.681	Macaca_nemestrina
ENSG00000183617	MRPL54	82	56.637	ENSMAMG00000003291	mrpl54	84	56.637	Mastacembelus_armatus
ENSG00000183617	MRPL54	62	63.529	ENSMZEG00005009023	mrpl54	60	60.577	Maylandia_zebra
ENSG00000183617	MRPL54	70	58.333	ENSMGAG00000000951	MRPL54	99	58.333	Meleagris_gallopavo
ENSG00000183617	MRPL54	100	71.014	ENSMAUG00000009543	Mrpl54	100	71.014	Mesocricetus_auratus
ENSG00000183617	MRPL54	100	84.783	ENSMICG00000034581	MRPL54	87	84.783	Microcebus_murinus
ENSG00000183617	MRPL54	100	74.638	ENSMOCG00000017895	Mrpl54	100	74.638	Microtus_ochrogaster
ENSG00000183617	MRPL54	67	60.215	ENSMMOG00000020370	mrpl54	74	60.215	Mola_mola
ENSG00000183617	MRPL54	100	71.942	ENSMODG00000000602	MRPL54	100	71.942	Monodelphis_domestica
ENSG00000183617	MRPL54	64	62.500	ENSMALG00000020280	mrpl54	73	61.538	Monopterus_albus
ENSG00000183617	MRPL54	100	66.667	MGP_CAROLIEiJ_G0015629	Mrpl54	100	68.841	Mus_caroli
ENSG00000183617	MRPL54	100	66.667	ENSMUSG00000034932	Mrpl54	100	68.841	Mus_musculus
ENSG00000183617	MRPL54	99	70.073	MGP_PahariEiJ_G0031042	Mrpl54	99	70.073	Mus_pahari
ENSG00000183617	MRPL54	100	65.942	MGP_SPRETEiJ_G0016447	Mrpl54	100	68.116	Mus_spretus
ENSG00000183617	MRPL54	77	80.189	ENSMLUG00000010801	MRPL54	100	80.189	Myotis_lucifugus
ENSG00000183617	MRPL54	100	71.223	ENSNGAG00000021044	Mrpl54	100	72.662	Nannospalax_galili
ENSG00000183617	MRPL54	64	60.227	ENSNBRG00000000568	mrpl54	73	59.615	Neolamprologus_brichardi
ENSG00000183617	MRPL54	99	70.803	ENSMEUG00000013033	MRPL54	99	70.803	Notamacropus_eugenii
ENSG00000183617	MRPL54	100	68.116	ENSOPRG00000010035	-	100	68.116	Ochotona_princeps
ENSG00000183617	MRPL54	100	76.812	ENSODEG00000013969	MRPL54	100	76.812	Octodon_degus
ENSG00000183617	MRPL54	64	61.364	ENSONIG00000002312	mrpl54	65	60.577	Oreochromis_niloticus
ENSG00000183617	MRPL54	69	57.292	ENSORLG00000016960	mrpl54	77	57.292	Oryzias_latipes
ENSG00000183617	MRPL54	67	58.065	ENSORLG00020014934	mrpl54	89	58.065	Oryzias_latipes_hni
ENSG00000183617	MRPL54	69	56.250	ENSORLG00015010788	mrpl54	75	56.250	Oryzias_latipes_hsok
ENSG00000183617	MRPL54	64	55.682	ENSOMEG00000009005	mrpl54	73	57.692	Oryzias_melastigma
ENSG00000183617	MRPL54	100	81.884	ENSOGAG00000033519	-	100	81.884	Otolemur_garnettii
ENSG00000183617	MRPL54	99	81.752	ENSOGAG00000026254	-	100	81.752	Otolemur_garnettii
ENSG00000183617	MRPL54	100	98.551	ENSPPAG00000042418	MRPL54	100	98.551	Pan_paniscus
ENSG00000183617	MRPL54	100	71.739	ENSPPRG00000012325	MRPL54	100	71.739	Panthera_pardus
ENSG00000183617	MRPL54	100	76.596	ENSPTIG00000017727	MRPL54	100	76.596	Panthera_tigris_altaica
ENSG00000183617	MRPL54	100	98.551	ENSPTRG00000010276	MRPL54	100	98.551	Pan_troglodytes
ENSG00000183617	MRPL54	100	88.406	ENSPANG00000033944	MRPL54	100	88.406	Papio_anubis
ENSG00000183617	MRPL54	86	51.667	ENSPKIG00000009984	mrpl54	68	51.667	Paramormyrops_kingsleyae
ENSG00000183617	MRPL54	67	65.217	ENSPSIG00000013587	MRPL54	96	65.217	Pelodiscus_sinensis
ENSG00000183617	MRPL54	64	56.818	ENSPMGG00000015972	mrpl54	76	53.390	Periophthalmus_magnuspinnatus
ENSG00000183617	MRPL54	100	73.913	ENSPEMG00000022929	Mrpl54	100	73.913	Peromyscus_maniculatus_bairdii
ENSG00000183617	MRPL54	100	68.345	ENSPCIG00000025383	MRPL54	100	68.345	Phascolarctos_cinereus
ENSG00000183617	MRPL54	75	56.731	ENSPFOG00000007409	mrpl54	73	56.731	Poecilia_formosa
ENSG00000183617	MRPL54	83	52.632	ENSPLAG00000001640	mrpl54	80	52.632	Poecilia_latipinna
ENSG00000183617	MRPL54	75	56.731	ENSPLAG00000001633	mrpl54	73	56.731	Poecilia_latipinna
ENSG00000183617	MRPL54	75	56.731	ENSPMEG00000021068	mrpl54	73	56.731	Poecilia_mexicana
ENSG00000183617	MRPL54	75	56.731	ENSPMEG00000021078	mrpl54	73	56.731	Poecilia_mexicana
ENSG00000183617	MRPL54	83	53.509	ENSPREG00000012425	mrpl54	80	53.509	Poecilia_reticulata
ENSG00000183617	MRPL54	100	94.928	ENSPPYG00000009386	MRPL54	100	94.928	Pongo_abelii
ENSG00000183617	MRPL54	100	78.261	ENSPCAG00000000690	MRPL54	100	78.261	Procavia_capensis
ENSG00000183617	MRPL54	100	81.884	ENSPCOG00000027550	MRPL54	100	81.884	Propithecus_coquereli
ENSG00000183617	MRPL54	62	62.353	ENSPNYG00000022006	mrpl54	60	59.615	Pundamilia_nyererei
ENSG00000183617	MRPL54	62	63.529	ENSPNAG00000000077	mrpl54	87	54.688	Pygocentrus_nattereri
ENSG00000183617	MRPL54	100	69.565	ENSRNOG00000020464	Mrpl54	100	69.565	Rattus_norvegicus
ENSG00000183617	MRPL54	100	86.957	ENSRBIG00000027038	MRPL54	100	86.957	Rhinopithecus_bieti
ENSG00000183617	MRPL54	100	86.957	ENSRROG00000018776	MRPL54	100	86.957	Rhinopithecus_roxellana
ENSG00000183617	MRPL54	100	80.435	ENSSBOG00000028081	MRPL54	100	80.435	Saimiri_boliviensis_boliviensis
ENSG00000183617	MRPL54	100	60.145	ENSSHAG00000002557	MRPL54	100	65.217	Sarcophilus_harrisii
ENSG00000183617	MRPL54	95	47.328	ENSSFOG00015008073	mrpl54	93	50.382	Scleropages_formosus
ENSG00000183617	MRPL54	64	61.364	ENSSMAG00000009226	mrpl54	83	55.932	Scophthalmus_maximus
ENSG00000183617	MRPL54	97	52.239	ENSSDUG00000009545	mrpl54	95	52.239	Seriola_dumerili
ENSG00000183617	MRPL54	97	50.746	ENSSLDG00000001781	mrpl54	95	50.746	Seriola_lalandi_dorsalis
ENSG00000183617	MRPL54	72	56.000	ENSSPUG00000015361	MRPL54	76	56.000	Sphenodon_punctatus
ENSG00000183617	MRPL54	97	49.254	ENSSPAG00000015601	mrpl54	95	49.254	Stegastes_partitus
ENSG00000183617	MRPL54	97	49.254	ENSSPAG00000003775	-	95	49.254	Stegastes_partitus
ENSG00000183617	MRPL54	100	76.087	ENSSSCG00000024242	MRPL54	100	76.087	Sus_scrofa
ENSG00000183617	MRPL54	64	59.091	ENSTRUG00000004609	mrpl54	83	54.237	Takifugu_rubripes
ENSG00000183617	MRPL54	64	54.545	ENSTNIG00000015468	mrpl54	83	50.847	Tetraodon_nigroviridis
ENSG00000183617	MRPL54	100	73.188	ENSTTRG00000004410	MRPL54	100	73.188	Tursiops_truncatus
ENSG00000183617	MRPL54	100	74.638	ENSUAMG00000021572	MRPL54	100	74.638	Ursus_americanus
ENSG00000183617	MRPL54	100	75.362	ENSUMAG00000007416	MRPL54	100	75.362	Ursus_maritimus
ENSG00000183617	MRPL54	100	76.087	ENSVVUG00000004420	MRPL54	100	76.087	Vulpes_vulpes
ENSG00000183617	MRPL54	88	59.504	ENSXETG00000033250	MRPL54	85	59.504	Xenopus_tropicalis
ENSG00000183617	MRPL54	64	56.818	ENSXMAG00000003500	mrpl54	80	54.386	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0003735	structural constituent of ribosome	21873635.	IBA	Function
GO:0005739	mitochondrion	28892042.	IDA	Component
GO:0005743	mitochondrial inner membrane	-	TAS	Component
GO:0005762	mitochondrial large ribosomal subunit	21873635.	IBA	Component
GO:0005762	mitochondrial large ribosomal subunit	25838379.28892042.	IDA	Component
GO:0070125	mitochondrial translational elongation	-	TAS	Process
GO:0070126	mitochondrial translational termination	-	TAS	Process