EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000183751 (Gene tree)
Gene ID: 10607
Gene Symbol: TBL3
Alias: SAZD|UTP13
Full Name: transducin beta like 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 10,897 bases
Position: chr16:1,972,037-1,982,933
Accession: 11587
RBP type: canonical RBP
Summary: The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene has multiple polyadenylation sites. It might have multiple alternatively spliced transcript variants but the variants have not been fully described yet. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000331815	Utp13	PF08625.11	5.4e-39	1	1
ENSP00000454836	Utp13	PF08625.11	6.8e-39	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000561907	TBL3-202	518	-	ENSP00000454735	77 (aa)	-	H3BN88
ENST00000332704	TBL3-201	2091	-	ENSP00000331815	697 (aa)	-	J3KNP2
ENST00000568546	TBL3-205	6803	-	ENSP00000454836	808 (aa)	-	Q12788
ENST00000564171	TBL3-203	917	-	-	- (aa)	-	-
ENST00000569628	TBL3-206	2594	-	-	- (aa)	-	-
ENST00000567615	TBL3-204	1047	-	-	- (aa)	-	-
ENST00000615855	TBL3-208	2472	-	ENSP00000481995	518 (aa)	-	A0A087WYP7
ENST00000569792	TBL3-207	856	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000183751's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03008	Ribosome biogenesis in eukaryotes	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000183751's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000183751	TBL3	72	30.000	ENSG00000164338	UTP15	58	30.000
ENSG00000183751	TBL3	73	31.613	ENSG00000196363	WDR5	94	31.613

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000183751	TBL3	97	62.453	ENSAPOG00000021308	tbl3	85	63.100	Acanthochromis_polyacanthus
ENSG00000183751	TBL3	96	88.932	ENSAMEG00000017654	TBL3	98	88.466	Ailuropoda_melanoleuca
ENSG00000183751	TBL3	98	61.988	ENSACIG00000007459	tbl3	99	61.988	Amphilophus_citrinellus
ENSG00000183751	TBL3	97	62.703	ENSAOCG00000000453	tbl3	85	62.829	Amphiprion_ocellaris
ENSG00000183751	TBL3	97	62.281	ENSAPEG00000010228	tbl3	98	62.406	Amphiprion_percula
ENSG00000183751	TBL3	97	63.000	ENSATEG00000024571	tbl3	94	62.803	Anabas_testudineus
ENSG00000183751	TBL3	97	59.169	ENSAPLG00000008515	TBL3	98	61.781	Anas_platyrhynchos
ENSG00000183751	TBL3	62	66.063	ENSACAG00000012119	-	82	66.063	Anolis_carolinensis
ENSG00000183751	TBL3	98	95.455	ENSANAG00000030472	TBL3	99	95.455	Aotus_nancymaae
ENSG00000183751	TBL3	97	62.108	ENSACLG00000027954	tbl3	99	58.313	Astatotilapia_calliptera
ENSG00000183751	TBL3	97	62.169	ENSAMXG00000042589	tbl3	86	62.169	Astyanax_mexicanus
ENSG00000183751	TBL3	99	89.711	ENSBTAG00000020366	TBL3	98	89.711	Bos_taurus
ENSG00000183751	TBL3	96	31.927	WBGene00013143	Y53C12B.1	99	31.219	Caenorhabditis_elegans
ENSG00000183751	TBL3	99	94.796	ENSCJAG00000015245	TBL3	99	94.796	Callithrix_jacchus
ENSG00000183751	TBL3	98	88.945	ENSCAFG00000019430	TBL3	98	90.406	Canis_familiaris
ENSG00000183751	TBL3	98	89.169	ENSCAFG00020026321	TBL3	99	89.169	Canis_lupus_dingo
ENSG00000183751	TBL3	99	89.837	ENSCHIG00000007747	TBL3	98	89.837	Capra_hircus
ENSG00000183751	TBL3	99	89.950	ENSTSYG00000036142	TBL3	99	89.950	Carlito_syrichta
ENSG00000183751	TBL3	97	84.076	ENSCAPG00000016762	TBL3	96	84.076	Cavia_aperea
ENSG00000183751	TBL3	99	90.226	ENSCPOG00000005998	TBL3	99	90.226	Cavia_porcellus
ENSG00000183751	TBL3	99	95.415	ENSCCAG00000034486	TBL3	99	95.415	Cebus_capucinus
ENSG00000183751	TBL3	100	96.411	ENSCATG00000031298	TBL3	100	96.411	Cercocebus_atys
ENSG00000183751	TBL3	99	91.604	ENSCLAG00000013342	TBL3	99	91.604	Chinchilla_lanigera
ENSG00000183751	TBL3	100	96.658	ENSCSAG00000011191	TBL3	100	96.658	Chlorocebus_sabaeus
ENSG00000183751	TBL3	99	65.644	ENSCPBG00000000253	TBL3	99	65.644	Chrysemys_picta_bellii
ENSG00000183751	TBL3	97	45.259	ENSCING00000009521	-	98	45.259	Ciona_intestinalis
ENSG00000183751	TBL3	100	96.411	ENSCANG00000031169	TBL3	100	96.411	Colobus_angolensis_palliatus
ENSG00000183751	TBL3	99	89.975	ENSCGRG00001021817	Tbl3	99	89.975	Cricetulus_griseus_chok1gshd
ENSG00000183751	TBL3	99	89.975	ENSCGRG00000013364	Tbl3	99	89.975	Cricetulus_griseus_crigri
ENSG00000183751	TBL3	98	61.414	ENSCSEG00000015634	tbl3	99	58.716	Cynoglossus_semilaevis
ENSG00000183751	TBL3	97	62.861	ENSCVAG00000002720	tbl3	99	61.722	Cyprinodon_variegatus
ENSG00000183751	TBL3	97	52.228	ENSDARG00000052344	tbl3	88	53.258	Danio_rerio
ENSG00000183751	TBL3	86	78.678	ENSDNOG00000019996	TBL3	89	78.678	Dasypus_novemcinctus
ENSG00000183751	TBL3	96	90.103	ENSDORG00000007377	Tbl3	98	89.581	Dipodomys_ordii
ENSG00000183751	TBL3	96	32.099	FBgn0033454	CG1671	99	32.099	Drosophila_melanogaster
ENSG00000183751	TBL3	96	87.805	ENSETEG00000019403	TBL3	87	90.210	Echinops_telfairi
ENSG00000183751	TBL3	97	56.433	ENSEBUG00000003526	tbl3	90	56.433	Eptatretus_burgeri
ENSG00000183751	TBL3	99	90.909	ENSEASG00005004649	TBL3	99	90.909	Equus_asinus_asinus
ENSG00000183751	TBL3	99	90.909	ENSECAG00000019299	TBL3	99	90.909	Equus_caballus
ENSG00000183751	TBL3	93	85.626	ENSEEUG00000000761	-	63	88.706	Erinaceus_europaeus
ENSG00000183751	TBL3	97	48.046	ENSELUG00000007394	tbl3	97	48.046	Esox_lucius
ENSG00000183751	TBL3	99	88.722	ENSFCAG00000011740	TBL3	99	88.722	Felis_catus
ENSG00000183751	TBL3	97	65.399	ENSFALG00000003409	TBL3	99	65.044	Ficedula_albicollis
ENSG00000183751	TBL3	99	90.100	ENSFDAG00000007751	TBL3	99	90.100	Fukomys_damarensis
ENSG00000183751	TBL3	97	61.905	ENSFHEG00000002234	tbl3	85	61.905	Fundulus_heteroclitus
ENSG00000183751	TBL3	97	50.297	ENSGMOG00000011562	tbl3	99	57.928	Gadus_morhua
ENSG00000183751	TBL3	98	65.293	ENSGALG00000005558	TBL3	99	65.418	Gallus_gallus
ENSG00000183751	TBL3	97	61.905	ENSGAFG00000020165	tbl3	87	61.905	Gambusia_affinis
ENSG00000183751	TBL3	98	60.644	ENSGACG00000011960	tbl3	99	60.644	Gasterosteus_aculeatus
ENSG00000183751	TBL3	97	65.700	ENSGAGG00000024028	TBL3	97	65.700	Gopherus_agassizii
ENSG00000183751	TBL3	100	99.257	ENSGGOG00000009378	TBL3	100	99.257	Gorilla_gorilla
ENSG00000183751	TBL3	98	61.615	ENSHBUG00000011872	tbl3	98	60.686	Haplochromis_burtoni
ENSG00000183751	TBL3	98	90.692	ENSHGLG00000002431	TBL3	99	90.692	Heterocephalus_glaber_female
ENSG00000183751	TBL3	98	89.182	ENSHGLG00100012878	TBL3	99	89.182	Heterocephalus_glaber_male
ENSG00000183751	TBL3	98	61.911	ENSHCOG00000016689	tbl3	87	62.035	Hippocampus_comes
ENSG00000183751	TBL3	97	60.500	ENSIPUG00000003568	TBL3	87	60.500	Ictalurus_punctatus
ENSG00000183751	TBL3	99	90.977	ENSSTOG00000012964	TBL3	99	90.977	Ictidomys_tridecemlineatus
ENSG00000183751	TBL3	99	88.986	ENSJJAG00000004124	Tbl3	99	88.986	Jaculus_jaculus
ENSG00000183751	TBL3	97	61.857	ENSKMAG00000020117	tbl3	99	60.574	Kryptolebias_marmoratus
ENSG00000183751	TBL3	98	60.714	ENSLBEG00000026742	tbl3	87	60.714	Labrus_bergylta
ENSG00000183751	TBL3	98	62.297	ENSLACG00000000615	TBL3	99	62.297	Latimeria_chalumnae
ENSG00000183751	TBL3	97	65.113	ENSLOCG00000008853	tbl3	87	64.039	Lepisosteus_oculatus
ENSG00000183751	TBL3	99	88.346	ENSLAFG00000004699	TBL3	99	88.346	Loxodonta_africana
ENSG00000183751	TBL3	100	96.906	ENSMFAG00000030302	TBL3	100	96.906	Macaca_fascicularis
ENSG00000183751	TBL3	100	96.782	ENSMMUG00000007943	TBL3	100	96.782	Macaca_mulatta
ENSG00000183751	TBL3	100	96.287	ENSMNEG00000032603	TBL3	100	96.287	Macaca_nemestrina
ENSG00000183751	TBL3	98	96.977	ENSMLEG00000043359	TBL3	100	96.977	Mandrillus_leucophaeus
ENSG00000183751	TBL3	98	62.005	ENSMAMG00000023507	tbl3	86	62.005	Mastacembelus_armatus
ENSG00000183751	TBL3	98	61.615	ENSMZEG00005000630	tbl3	98	57.908	Maylandia_zebra
ENSG00000183751	TBL3	99	63.492	ENSMGAG00000005694	TBL3	99	64.375	Meleagris_gallopavo
ENSG00000183751	TBL3	99	89.724	ENSMAUG00000008718	Tbl3	99	89.724	Mesocricetus_auratus
ENSG00000183751	TBL3	99	92.813	ENSMICG00000012787	TBL3	88	92.813	Microcebus_murinus
ENSG00000183751	TBL3	99	89.850	ENSMOCG00000019634	Tbl3	99	89.850	Microtus_ochrogaster
ENSG00000183751	TBL3	98	60.546	ENSMMOG00000007551	tbl3	99	60.315	Mola_mola
ENSG00000183751	TBL3	99	74.226	ENSMODG00000016091	TBL3	99	74.226	Monodelphis_domestica
ENSG00000183751	TBL3	98	62.283	ENSMALG00000007013	tbl3	86	62.283	Monopterus_albus
ENSG00000183751	TBL3	98	90.000	MGP_CAROLIEiJ_G0021199	Tbl3	99	89.850	Mus_caroli
ENSG00000183751	TBL3	98	89.747	ENSMUSG00000040688	Tbl3	99	89.933	Mus_musculus
ENSG00000183751	TBL3	98	90.127	MGP_PahariEiJ_G0023516	Tbl3	99	89.975	Mus_pahari
ENSG00000183751	TBL3	98	90.127	MGP_SPRETEiJ_G0022110	Tbl3	100	89.933	Mus_spretus
ENSG00000183751	TBL3	99	89.348	ENSMPUG00000015545	TBL3	99	89.348	Mustela_putorius_furo
ENSG00000183751	TBL3	98	89.686	ENSMLUG00000011684	TBL3	99	89.686	Myotis_lucifugus
ENSG00000183751	TBL3	99	89.724	ENSNGAG00000002428	Tbl3	99	89.724	Nannospalax_galili
ENSG00000183751	TBL3	99	59.436	ENSNBRG00000003173	tbl3	99	59.436	Neolamprologus_brichardi
ENSG00000183751	TBL3	100	97.401	ENSNLEG00000008889	TBL3	99	97.401	Nomascus_leucogenys
ENSG00000183751	TBL3	98	67.989	ENSMEUG00000004011	TBL3	99	70.516	Notamacropus_eugenii
ENSG00000183751	TBL3	98	87.683	ENSOPRG00000002527	-	99	83.123	Ochotona_princeps
ENSG00000183751	TBL3	99	89.850	ENSODEG00000013930	TBL3	99	90.306	Octodon_degus
ENSG00000183751	TBL3	99	61.302	ENSONIG00000002319	tbl3	99	61.302	Oreochromis_niloticus
ENSG00000183751	TBL3	96	66.541	ENSOANG00000009819	TBL3	99	66.541	Ornithorhynchus_anatinus
ENSG00000183751	TBL3	98	62.701	ENSORLG00000009312	tbl3	95	62.593	Oryzias_latipes
ENSG00000183751	TBL3	98	62.469	ENSORLG00020017711	tbl3	95	62.469	Oryzias_latipes_hni
ENSG00000183751	TBL3	98	62.454	ENSORLG00015007004	tbl3	86	62.454	Oryzias_latipes_hsok
ENSG00000183751	TBL3	99	62.868	ENSOMEG00000012684	tbl3	97	61.172	Oryzias_melastigma
ENSG00000183751	TBL3	99	88.529	ENSOGAG00000010104	TBL3	100	88.529	Otolemur_garnettii
ENSG00000183751	TBL3	89	78.053	ENSOARG00000017059	TBL3	99	80.835	Ovis_aries
ENSG00000183751	TBL3	100	99.381	ENSPPAG00000041939	TBL3	100	99.381	Pan_paniscus
ENSG00000183751	TBL3	99	87.970	ENSPPRG00000000893	TBL3	99	87.970	Panthera_pardus
ENSG00000183751	TBL3	98	86.809	ENSPTIG00000010377	TBL3	99	86.809	Panthera_tigris_altaica
ENSG00000183751	TBL3	100	99.134	ENSPTRG00000007621	TBL3	100	99.134	Pan_troglodytes
ENSG00000183751	TBL3	100	96.411	ENSPANG00000007024	TBL3	100	96.411	Papio_anubis
ENSG00000183751	TBL3	99	61.406	ENSPKIG00000000136	tbl3	89	61.406	Paramormyrops_kingsleyae
ENSG00000183751	TBL3	97	64.698	ENSPSIG00000013024	TBL3	97	64.698	Pelodiscus_sinensis
ENSG00000183751	TBL3	97	60.309	ENSPMGG00000020660	tbl3	95	61.421	Periophthalmus_magnuspinnatus
ENSG00000183751	TBL3	98	90.038	ENSPEMG00000009768	Tbl3	99	90.397	Peromyscus_maniculatus_bairdii
ENSG00000183751	TBL3	96	51.631	ENSPMAG00000004860	tbl3	93	53.551	Petromyzon_marinus
ENSG00000183751	TBL3	99	74.318	ENSPCIG00000021811	TBL3	99	74.318	Phascolarctos_cinereus
ENSG00000183751	TBL3	97	62.030	ENSPFOG00000009834	tbl3	86	62.030	Poecilia_formosa
ENSG00000183751	TBL3	97	62.030	ENSPLAG00000016437	tbl3	86	62.030	Poecilia_latipinna
ENSG00000183751	TBL3	97	62.030	ENSPMEG00000019513	tbl3	86	62.030	Poecilia_mexicana
ENSG00000183751	TBL3	100	97.525	ENSPPYG00000006977	TBL3	100	97.525	Pongo_abelii
ENSG00000183751	TBL3	99	92.193	ENSPCOG00000019749	TBL3	99	92.193	Propithecus_coquereli
ENSG00000183751	TBL3	98	89.886	ENSPVAG00000016710	TBL3	99	89.886	Pteropus_vampyrus
ENSG00000183751	TBL3	99	56.581	ENSPNYG00000017137	tbl3	99	56.581	Pundamilia_nyererei
ENSG00000183751	TBL3	97	60.902	ENSPNAG00000017527	tbl3	97	59.067	Pygocentrus_nattereri
ENSG00000183751	TBL3	99	89.348	ENSRNOG00000013429	Tbl3	99	89.348	Rattus_norvegicus
ENSG00000183751	TBL3	100	90.853	ENSRBIG00000032982	TBL3	100	90.853	Rhinopithecus_bieti
ENSG00000183751	TBL3	100	96.287	ENSRROG00000026697	TBL3	100	96.287	Rhinopithecus_roxellana
ENSG00000183751	TBL3	96	30.182	YLR222C	-	99	30.182	Saccharomyces_cerevisiae
ENSG00000183751	TBL3	99	95.663	ENSSBOG00000013923	TBL3	99	95.663	Saimiri_boliviensis_boliviensis
ENSG00000183751	TBL3	99	74.069	ENSSHAG00000015266	TBL3	99	74.069	Sarcophilus_harrisii
ENSG00000183751	TBL3	97	61.798	ENSSFOG00015023537	tbl3	85	61.798	Scleropages_formosus
ENSG00000183751	TBL3	97	62.516	ENSSMAG00000014338	tbl3	98	62.516	Scophthalmus_maximus
ENSG00000183751	TBL3	98	62.116	ENSSDUG00000008158	tbl3	86	62.239	Seriola_dumerili
ENSG00000183751	TBL3	98	61.776	ENSSLDG00000023733	tbl3	99	60.099	Seriola_lalandi_dorsalis
ENSG00000183751	TBL3	53	86.667	ENSSARG00000010958	-	57	86.667	Sorex_araneus
ENSG00000183751	TBL3	95	52.931	ENSSPUG00000012939	TBL3	98	52.931	Sphenodon_punctatus
ENSG00000183751	TBL3	97	62.005	ENSSPAG00000010659	tbl3	87	62.005	Stegastes_partitus
ENSG00000183751	TBL3	99	90.464	ENSSSCG00000037686	TBL3	99	90.464	Sus_scrofa
ENSG00000183751	TBL3	97	63.811	ENSTGUG00000006592	-	99	63.811	Taeniopygia_guttata
ENSG00000183751	TBL3	97	60.349	ENSTRUG00000007010	tbl3	86	60.549	Takifugu_rubripes
ENSG00000183751	TBL3	98	60.902	ENSTNIG00000018011	tbl3	99	61.384	Tetraodon_nigroviridis
ENSG00000183751	TBL3	52	94.304	ENSTBEG00000000017	-	53	94.304	Tupaia_belangeri
ENSG00000183751	TBL3	99	87.562	ENSTTRG00000011395	TBL3	99	87.562	Tursiops_truncatus
ENSG00000183751	TBL3	98	89.607	ENSUAMG00000019276	TBL3	99	89.335	Ursus_americanus
ENSG00000183751	TBL3	98	83.641	ENSUMAG00000022149	TBL3	99	84.131	Ursus_maritimus
ENSG00000183751	TBL3	99	89.210	ENSVVUG00000009589	TBL3	99	89.210	Vulpes_vulpes
ENSG00000183751	TBL3	97	55.583	ENSXETG00000007217	tbl3	96	55.583	Xenopus_tropicalis
ENSG00000183751	TBL3	97	61.905	ENSXCOG00000010277	tbl3	99	61.905	Xiphophorus_couchianus
ENSG00000183751	TBL3	97	62.155	ENSXMAG00000014866	tbl3	97	60.633	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	21873635.	IBA	Process
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0005515	protein binding	16189514.25416956.	IPI	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0006364	rRNA processing	-	TAS	Process
GO:0032040	small-subunit processome	21873635.	IBA	Component
GO:0034388	Pwp2p-containing subcomplex of 90S preribosome	21873635.	IBA	Component