EuRBPDB

Description

Ensembl ID: ENSG00000184083 (Gene tree)
Gene ID: 54954
Gene Symbol: FAM120C
Alias: ORF34|FLJ20506|CXorf17
Full Name: family with sequence similarity 120C
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 114,958 bases
Position: chrX:54,068,324-54,183,281
Accession: 16949
RBP type: non-canonical RBP
Summary: This gene encodes a potential transmembrane protein and lies in a region where mutations and deletions have been associated with intellectual disability and autism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
30742606	mRNA dynamics and alternative conformations adopted under low and high arginine concentrations control polyamine biosynthesis in Salmonella.	PLoS Genet	2019 Feb 11	Ben-Zvi T	doi: 10.1371/journal.pgen.1007646

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000477084	FAM120C-203	1140	-	ENSP00000420718	238 (aa)	-	Q9NX05
ENST00000497680	FAM120C-204	637	-	-	- (aa)	-	-
ENST00000328235	FAM120C-201	3716	-	ENSP00000329896	895 (aa)	-	F8W881
ENST00000375180	FAM120C-202	8057	XM_006724589	ENSP00000364324	1096 (aa)	XP_006724652	Q9NX05

Gene Model

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000184083	FAM120C	90	87.879	ENSDARG00000019205	fam120c	95	90.000	Danio_rerio
ENSG00000184083	FAM120C	90	54.686	ENSG00000048828	FAM120A	100	59.681	Homo_sapiens
ENSG00000184083	FAM120C	98	94.017	ENSMUSG00000025262	Fam120c	100	91.712	Mus_musculus
ENSG00000184083	FAM120C	90	54.803	ENSMUSG00000038014	Fam120a	96	54.972	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005634	nucleus	21873635.	IBA	Component