EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000184110 (Gene tree)
Gene ID: 8663
Gene Symbol: EIF3C
Alias: eIF3-p110|eIF3c|EIF3S8
Full Name: eukaryotic translation initiation factor 3 subunit C
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 47,173 bases
Position: chr16:28,688,558-28,735,730
Accession: 3279
RBP type: canonical RBP
Summary: (Eukaryotic Translation Initiation Factor 3 Subunit C) is a Protein Coding gene. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S. Gene Ontology (GO) annotations related to this gene include translation initiation factor activity. An important paralog of this gene is EIF3CL.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000332604	eIF-3c_N	PF05470.12	8.4e-273	1	1
ENSP00000378953	eIF-3c_N	PF05470.12	8.4e-273	1	1
ENSP00000457418	eIF-3c_N	PF05470.12	8.4e-273	1	1
ENSP00000457963	eIF-3c_N	PF05470.12	8.4e-273	1	1
ENSP00000456416	eIF-3c_N	PF05470.12	7e-264	1	1
ENSP00000455278	eIF-3c_N	PF05470.12	7e-52	1	1
ENSP00000455277	eIF-3c_N	PF05470.12	1.4e-49	1	1
ENSP00000457389	eIF-3c_N	PF05470.12	1.7e-32	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
23766293	Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation.	Nucleic Acids Res	2013 Aug	Sun C	doi: 10.1093/nar/gkt510
22016036	The interaction between human initiation factor eIF3 subunit c and heat-shock protein 90: a necessary factor for translation mediated by the hepatitis C virus internal ribosome entry site.	Virus Res	2012 Jan	Ujino S	doi: 10.1016/j.virusres.2011.10.003
28231410	Transcriptomic analyses of RNA-binding proteins reveal eIF3c promotes cell proliferation in hepatocellular carcinoma.	Cancer Sci	2017 May	Li T	doi: 10.1111/cas.13209
27947744	-	-	-	-	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000569690	EIF3C-214	581	-	ENSP00000455278	148 (aa)	-	H3BPE4
ENST00000566866	EIF3C-211	2986	-	ENSP00000457418	913 (aa)	-	Q99613
ENST00000395587	EIF3C-202	3137	XM_017023814	ENSP00000378953	913 (aa)	XP_016879303	Q99613
ENST00000566519	EIF3C-210	620	-	-	- (aa)	-	-
ENST00000568426	EIF3C-212	572	-	ENSP00000455277	132 (aa)	-	H3BPE3
ENST00000566086	EIF3C-208	424	-	-	- (aa)	-	-
ENST00000565099	EIF3C-206	588	-	-	- (aa)	-	-
ENST00000566501	EIF3C-209	3128	-	ENSP00000457963	913 (aa)	-	Q99613
ENST00000569005	EIF3C-213	610	-	-	- (aa)	-	-
ENST00000563139	EIF3C-203	516	-	ENSP00000457389	79 (aa)	-	H3BTY8
ENST00000565932	EIF3C-207	3957	-	-	- (aa)	-	-
ENST00000331666	EIF3C-201	3145	-	ENSP00000332604	913 (aa)	-	Q99613
ENST00000564243	EIF3C-204	2870	-	ENSP00000456416	903 (aa)	-	Q99613
ENST00000564839	EIF3C-205	586	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000184110's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03013	RNA transport	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000184110's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000184110	EIF3C	100	100.000	ENSG00000205609	EIF3CL	100	99.891

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000184110	EIF3C	100	84.810	ENSAPOG00000024092	eif3c	92	84.339	Acanthochromis_polyacanthus
ENSG00000184110	EIF3C	100	100.000	ENSAMEG00000015454	-	100	98.686	Ailuropoda_melanoleuca
ENSG00000184110	EIF3C	100	83.544	ENSACIG00000015082	eif3c	99	70.460	Amphilophus_citrinellus
ENSG00000184110	EIF3C	100	84.810	ENSAOCG00000021466	eif3c	98	76.823	Amphiprion_ocellaris
ENSG00000184110	EIF3C	100	79.747	ENSAOCG00000024752	-	55	68.387	Amphiprion_ocellaris
ENSG00000184110	EIF3C	100	84.810	ENSAPEG00000010521	eif3c	98	76.823	Amphiprion_percula
ENSG00000184110	EIF3C	100	81.013	ENSAPEG00000023503	-	62	69.032	Amphiprion_percula
ENSG00000184110	EIF3C	100	84.810	ENSATEG00000019001	eif3c	98	76.630	Anabas_testudineus
ENSG00000184110	EIF3C	100	98.734	ENSACAG00000005937	-	100	86.354	Anolis_carolinensis
ENSG00000184110	EIF3C	100	100.000	ENSANAG00000020640	-	100	99.890	Aotus_nancymaae
ENSG00000184110	EIF3C	100	83.544	ENSACLG00000009322	eif3c	92	80.619	Astatotilapia_calliptera
ENSG00000184110	EIF3C	100	84.810	ENSACLG00000009347	eif3c	98	83.471	Astatotilapia_calliptera
ENSG00000184110	EIF3C	100	84.810	ENSAMXG00000020949	eif3c	98	76.638	Astyanax_mexicanus
ENSG00000184110	EIF3C	100	100.000	ENSBTAG00000006543	EIF3CL	100	98.028	Bos_taurus
ENSG00000184110	EIF3C	95	50.649	WBGene00001226	eif-3.C	93	43.243	Caenorhabditis_elegans
ENSG00000184110	EIF3C	100	100.000	ENSCJAG00000006341	-	100	99.671	Callithrix_jacchus
ENSG00000184110	EIF3C	100	100.000	ENSCAFG00000017143	-	100	98.576	Canis_familiaris
ENSG00000184110	EIF3C	100	100.000	ENSCAFG00020017587	-	100	98.686	Canis_lupus_dingo
ENSG00000184110	EIF3C	100	100.000	ENSCHIG00000024795	-	100	97.919	Capra_hircus
ENSG00000184110	EIF3C	100	100.000	ENSTSYG00000003486	-	100	98.357	Carlito_syrichta
ENSG00000184110	EIF3C	100	100.000	ENSCAPG00000015887	-	100	88.675	Cavia_aperea
ENSG00000184110	EIF3C	100	100.000	ENSCPOG00000007533	-	100	98.138	Cavia_porcellus
ENSG00000184110	EIF3C	100	88.608	ENSCCAG00000029099	-	99	83.187	Cebus_capucinus
ENSG00000184110	EIF3C	100	100.000	ENSCCAG00000034928	-	100	98.686	Cebus_capucinus
ENSG00000184110	EIF3C	100	95.946	ENSCCAG00000027724	-	100	94.524	Cebus_capucinus
ENSG00000184110	EIF3C	100	100.000	ENSCATG00000032673	-	100	99.890	Cercocebus_atys
ENSG00000184110	EIF3C	100	100.000	ENSCLAG00000011094	-	100	97.590	Chinchilla_lanigera
ENSG00000184110	EIF3C	100	100.000	ENSCSAG00000006297	-	100	99.890	Chlorocebus_sabaeus
ENSG00000184110	EIF3C	55	82.239	ENSCHOG00000003120	-	88	82.239	Choloepus_hoffmanni
ENSG00000184110	EIF3C	100	97.468	ENSCPBG00000012407	-	92	83.537	Chrysemys_picta_bellii
ENSG00000184110	EIF3C	97	57.143	ENSCSAVG00000006744	-	96	57.018	Ciona_savignyi
ENSG00000184110	EIF3C	100	100.000	ENSCANG00000033626	-	100	99.890	Colobus_angolensis_palliatus
ENSG00000184110	EIF3C	100	100.000	ENSCGRG00001015265	EIF3C	100	96.933	Cricetulus_griseus_chok1gshd
ENSG00000184110	EIF3C	100	100.000	ENSCGRG00000006124	-	99	94.400	Cricetulus_griseus_crigri
ENSG00000184110	EIF3C	100	84.810	ENSCSEG00000017770	eif3c	100	74.672	Cynoglossus_semilaevis
ENSG00000184110	EIF3C	100	84.810	ENSCVAG00000005402	eif3c	98	81.656	Cyprinodon_variegatus
ENSG00000184110	EIF3C	100	83.544	ENSDARG00000016443	eif3c	98	76.387	Danio_rerio
ENSG00000184110	EIF3C	100	100.000	ENSDNOG00000031497	-	100	98.467	Dasypus_novemcinctus
ENSG00000184110	EIF3C	100	100.000	ENSDORG00000016471	Eif3c	100	98.357	Dipodomys_ordii
ENSG00000184110	EIF3C	97	57.500	FBgn0034258	eIF3c	95	50.885	Drosophila_melanogaster
ENSG00000184110	EIF3C	100	98.734	ENSETEG00000013527	-	92	98.624	Echinops_telfairi
ENSG00000184110	EIF3C	100	68.354	ENSEBUG00000001629	eif3c	99	63.402	Eptatretus_burgeri
ENSG00000184110	EIF3C	100	100.000	ENSECAG00000008746	-	100	98.576	Equus_caballus
ENSG00000184110	EIF3C	65	64.286	ENSEEUG00000000726	-	64	64.286	Erinaceus_europaeus
ENSG00000184110	EIF3C	100	100.000	ENSEEUG00000006148	-	100	97.494	Erinaceus_europaeus
ENSG00000184110	EIF3C	100	86.076	ENSELUG00000022257	eif3c	92	83.748	Esox_lucius
ENSG00000184110	EIF3C	100	100.000	ENSFCAG00000015782	-	100	98.467	Felis_catus
ENSG00000184110	EIF3C	100	100.000	ENSFDAG00000003588	-	100	97.919	Fukomys_damarensis
ENSG00000184110	EIF3C	100	84.810	ENSFHEG00000014154	EIF3C	93	83.660	Fundulus_heteroclitus
ENSG00000184110	EIF3C	100	81.013	ENSGMOG00000016885	eif3c	99	75.897	Gadus_morhua
ENSG00000184110	EIF3C	73	81.481	ENSGALG00000047139	-	65	85.714	Gallus_gallus
ENSG00000184110	EIF3C	100	82.278	ENSGACG00000007652	eif3c	100	75.900	Gasterosteus_aculeatus
ENSG00000184110	EIF3C	100	97.468	ENSGAGG00000006666	-	100	83.825	Gopherus_agassizii
ENSG00000184110	EIF3C	100	100.000	ENSGGOG00000022677	-	100	99.614	Gorilla_gorilla
ENSG00000184110	EIF3C	100	100.000	ENSGGOG00000026919	EIF3C	100	99.772	Gorilla_gorilla
ENSG00000184110	EIF3C	100	100.000	ENSHGLG00000011445	EIF3C	100	97.700	Heterocephalus_glaber_female
ENSG00000184110	EIF3C	100	100.000	ENSHGLG00100000217	EIF3C	100	97.700	Heterocephalus_glaber_male
ENSG00000184110	EIF3C	100	84.810	ENSHCOG00000019694	eif3c	98	75.682	Hippocampus_comes
ENSG00000184110	EIF3C	100	83.544	ENSIPUG00000016878	eif3c	98	76.304	Ictalurus_punctatus
ENSG00000184110	EIF3C	100	100.000	ENSSTOG00000021278	-	100	98.686	Ictidomys_tridecemlineatus
ENSG00000184110	EIF3C	100	100.000	ENSJJAG00000012722	Eif3c	100	97.043	Jaculus_jaculus
ENSG00000184110	EIF3C	100	84.810	ENSKMAG00000021662	eif3c	97	76.580	Kryptolebias_marmoratus
ENSG00000184110	EIF3C	100	84.810	ENSLBEG00000023370	eif3c	99	74.651	Labrus_bergylta
ENSG00000184110	EIF3C	100	92.405	ENSLACG00000000770	eif3c	100	80.305	Latimeria_chalumnae
ENSG00000184110	EIF3C	100	100.000	ENSLAFG00000027426	-	100	97.919	Loxodonta_africana
ENSG00000184110	EIF3C	100	100.000	ENSMFAG00000041930	-	100	99.890	Macaca_fascicularis
ENSG00000184110	EIF3C	100	100.000	ENSMMUG00000011798	-	100	99.890	Macaca_mulatta
ENSG00000184110	EIF3C	100	100.000	ENSMNEG00000023915	-	100	99.890	Macaca_nemestrina
ENSG00000184110	EIF3C	100	100.000	ENSMLEG00000027529	-	100	99.890	Mandrillus_leucophaeus
ENSG00000184110	EIF3C	100	84.810	ENSMAMG00000012512	eif3c	95	84.667	Mastacembelus_armatus
ENSG00000184110	EIF3C	100	83.544	ENSMZEG00005013685	eif3c	92	80.782	Maylandia_zebra
ENSG00000184110	EIF3C	100	84.810	ENSMZEG00005013699	eif3c	98	83.471	Maylandia_zebra
ENSG00000184110	EIF3C	100	100.000	ENSMAUG00000010621	Eif3c	100	96.824	Mesocricetus_auratus
ENSG00000184110	EIF3C	100	100.000	ENSMICG00000036748	-	100	98.467	Microcebus_murinus
ENSG00000184110	EIF3C	100	100.000	ENSMOCG00000004204	Eif3c	100	94.414	Microtus_ochrogaster
ENSG00000184110	EIF3C	100	84.810	ENSMMOG00000001572	eif3c	72	82.673	Mola_mola
ENSG00000184110	EIF3C	100	95.946	ENSMODG00000015579	-	100	95.077	Monodelphis_domestica
ENSG00000184110	EIF3C	100	83.544	ENSMALG00000008907	eif3c	92	84.437	Monopterus_albus
ENSG00000184110	EIF3C	100	100.000	MGP_CAROLIEiJ_G0030451	Eif3c	100	96.714	Mus_caroli
ENSG00000184110	EIF3C	100	100.000	ENSMUSG00000030738	Eif3c	100	96.714	Mus_musculus
ENSG00000184110	EIF3C	100	100.000	MGP_PahariEiJ_G0013661	Eif3c	100	96.276	Mus_pahari
ENSG00000184110	EIF3C	100	100.000	MGP_SPRETEiJ_G0031565	Eif3c	100	96.714	Mus_spretus
ENSG00000184110	EIF3C	100	100.000	ENSMPUG00000012732	-	100	97.955	Mustela_putorius_furo
ENSG00000184110	EIF3C	100	100.000	ENSMLUG00000015558	-	100	97.043	Myotis_lucifugus
ENSG00000184110	EIF3C	93	87.273	ENSNGAG00000010901	-	98	87.273	Nannospalax_galili
ENSG00000184110	EIF3C	100	100.000	ENSNGAG00000007177	-	100	97.700	Nannospalax_galili
ENSG00000184110	EIF3C	100	100.000	ENSNLEG00000001425	-	91	93.333	Nomascus_leucogenys
ENSG00000184110	EIF3C	95	78.667	ENSMEUG00000005317	-	100	61.392	Notamacropus_eugenii
ENSG00000184110	EIF3C	100	77.923	ENSMEUG00000009939	-	99	77.948	Notamacropus_eugenii
ENSG00000184110	EIF3C	100	99.324	ENSOPRG00000000931	-	100	98.028	Ochotona_princeps
ENSG00000184110	EIF3C	100	100.000	ENSODEG00000013508	-	100	97.809	Octodon_degus
ENSG00000184110	EIF3C	66	63.201	ENSONIG00000011434	eif3c	99	63.201	Oreochromis_niloticus
ENSG00000184110	EIF3C	100	98.734	ENSOANG00000011410	-	100	91.272	Ornithorhynchus_anatinus
ENSG00000184110	EIF3C	100	100.000	ENSOCUG00000022489	-	100	98.576	Oryctolagus_cuniculus
ENSG00000184110	EIF3C	100	83.544	ENSORLG00000006318	eif3c	98	72.148	Oryzias_latipes
ENSG00000184110	EIF3C	100	83.544	ENSORLG00020015713	eif3c	96	82.881	Oryzias_latipes_hni
ENSG00000184110	EIF3C	100	83.544	ENSORLG00015013772	eif3c	97	74.614	Oryzias_latipes_hsok
ENSG00000184110	EIF3C	100	84.810	ENSOMEG00000020450	eif3c	100	74.329	Oryzias_melastigma
ENSG00000184110	EIF3C	100	100.000	ENSOGAG00000012737	-	100	98.357	Otolemur_garnettii
ENSG00000184110	EIF3C	100	100.000	ENSOARG00000002892	-	100	97.919	Ovis_aries
ENSG00000184110	EIF3C	100	100.000	ENSPPRG00000012336	-	100	98.467	Panthera_pardus
ENSG00000184110	EIF3C	100	100.000	ENSPTIG00000011712	-	100	98.467	Panthera_tigris_altaica
ENSG00000184110	EIF3C	100	100.000	ENSPANG00000021151	-	100	99.890	Papio_anubis
ENSG00000184110	EIF3C	100	84.810	ENSPKIG00000002049	eif3c	98	77.233	Paramormyrops_kingsleyae
ENSG00000184110	EIF3C	100	84.810	ENSPMGG00000005409	eif3c	94	84.743	Periophthalmus_magnuspinnatus
ENSG00000184110	EIF3C	100	100.000	ENSPEMG00000010899	Eif3c	100	95.509	Peromyscus_maniculatus_bairdii
ENSG00000184110	EIF3C	100	98.734	ENSPCIG00000025206	-	100	95.077	Phascolarctos_cinereus
ENSG00000184110	EIF3C	100	84.810	ENSPFOG00000004476	eif3c	98	75.461	Poecilia_formosa
ENSG00000184110	EIF3C	100	84.810	ENSPLAG00000017480	eif3c	98	75.529	Poecilia_latipinna
ENSG00000184110	EIF3C	100	84.810	ENSPMEG00000019512	eif3c	98	75.543	Poecilia_mexicana
ENSG00000184110	EIF3C	100	100.000	ENSPPYG00000007227	-	100	96.605	Pongo_abelii
ENSG00000184110	EIF3C	67	98.502	ENSPCAG00000012710	-	100	98.502	Procavia_capensis
ENSG00000184110	EIF3C	100	100.000	ENSPCOG00000019289	-	100	98.905	Propithecus_coquereli
ENSG00000184110	EIF3C	100	100.000	ENSPVAG00000005804	-	100	98.138	Pteropus_vampyrus
ENSG00000184110	EIF3C	100	83.544	ENSPNYG00000016530	eif3c	81	81.818	Pundamilia_nyererei
ENSG00000184110	EIF3C	100	83.544	ENSPNAG00000024040	eif3c	99	77.049	Pygocentrus_nattereri
ENSG00000184110	EIF3C	100	98.734	ENSRNOG00000018761	Eif3c	100	96.166	Rattus_norvegicus
ENSG00000184110	EIF3C	100	100.000	ENSRBIG00000044009	-	98	97.433	Rhinopithecus_bieti
ENSG00000184110	EIF3C	100	100.000	ENSRROG00000043626	-	100	99.890	Rhinopithecus_roxellana
ENSG00000184110	EIF3C	77	31.365	YMR309C	-	81	30.699	Saccharomyces_cerevisiae
ENSG00000184110	EIF3C	100	100.000	ENSSBOG00000032155	-	100	99.562	Saimiri_boliviensis_boliviensis
ENSG00000184110	EIF3C	100	98.734	ENSSHAG00000011808	-	100	94.677	Sarcophilus_harrisii
ENSG00000184110	EIF3C	100	84.810	ENSSFOG00015021823	eif3c	98	76.393	Scleropages_formosus
ENSG00000184110	EIF3C	100	84.810	ENSSMAG00000016638	eif3c	97	77.069	Scophthalmus_maximus
ENSG00000184110	EIF3C	100	84.810	ENSSDUG00000023117	eif3c	98	76.471	Seriola_dumerili
ENSG00000184110	EIF3C	100	84.810	ENSSLDG00000009706	eif3c	93	83.660	Seriola_lalandi_dorsalis
ENSG00000184110	EIF3C	100	97.468	ENSSPUG00000016470	-	100	84.590	Sphenodon_punctatus
ENSG00000184110	EIF3C	100	84.810	ENSSPAG00000000426	eif3c	100	76.413	Stegastes_partitus
ENSG00000184110	EIF3C	100	100.000	ENSSSCG00000034927	-	100	98.686	Sus_scrofa
ENSG00000184110	EIF3C	100	83.544	ENSTRUG00000008951	eif3c	99	74.920	Takifugu_rubripes
ENSG00000184110	EIF3C	100	83.544	ENSTNIG00000015210	eif3c	100	74.891	Tetraodon_nigroviridis
ENSG00000184110	EIF3C	100	100.000	ENSTTRG00000005880	-	100	98.248	Tursiops_truncatus
ENSG00000184110	EIF3C	73	98.779	ENSUAMG00000001127	-	91	100.000	Ursus_americanus
ENSG00000184110	EIF3C	100	100.000	ENSUMAG00000010927	-	100	98.576	Ursus_maritimus
ENSG00000184110	EIF3C	100	100.000	ENSVVUG00000025970	-	100	97.152	Vulpes_vulpes
ENSG00000184110	EIF3C	100	89.873	ENSXETG00000002941	eif3c	100	79.072	Xenopus_tropicalis
ENSG00000184110	EIF3C	100	84.810	ENSXMAG00000013796	eif3c	100	75.054	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001732	formation of cytoplasmic translation initiation complex	-	IEA	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003743	translation initiation factor activity	21873635.	IBA	Function
GO:0003743	translation initiation factor activity	17322308.18599441.	IC	Function
GO:0003743	translation initiation factor activity	17581632.25849773.	IDA	Function
GO:0005515	protein binding	10504338.18599441.18628297.22190034.22323517.23623729.24092755.29426014.	IPI	Function
GO:0005829	cytosol	-	TAS	Component
GO:0005852	eukaryotic translation initiation factor 3 complex	21873635.	IBA	Component
GO:0005852	eukaryotic translation initiation factor 3 complex	17322308.17581632.18599441.25849773.	IDA	Component
GO:0006413	translational initiation	21873635.	IBA	Process
GO:0006413	translational initiation	17322308.18599441.	IC	Process
GO:0006413	translational initiation	17581632.	IDA	Process
GO:0006413	translational initiation	-	TAS	Process
GO:0016282	eukaryotic 43S preinitiation complex	-	IEA	Component
GO:0031369	translation initiation factor binding	21873635.	IBA	Function
GO:0033290	eukaryotic 48S preinitiation complex	-	IEA	Component
GO:0045727	positive regulation of translation	24092755.	IPI	Process
GO:1902416	positive regulation of mRNA binding	24092755.	IPI	Process