EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000184209 (Gene tree)
Gene ID: 11066
Gene Symbol: SNRNP35
Alias: U1SNRNPBP
Full Name: small nuclear ribonucleoprotein U11/U12 subunit 35
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 15,514 bases
Position: chr12:123,457,641-123,473,154
Accession: 30852
RBP type: canonical RBP
Summary: The protein encoded by this gene is a homolog of the U1-snRNP binding protein. The N-terminal half contains a RNA recognition motif and the C-terminal half is rich in Arg/Asp and Arg/Glu dipeptides, which is a characteristic of a variety of splicing factors. This protein is a component of the U11/U12 small nuclear ribonucleoproteins (snRNP) that form part of the U12-type spliceosome. Alternative splicing results in multiple transcript variants encoding two distinct isoforms and representing a non-protein coding variant. [provided by RefSeq, Aug 2013]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000340774	RRM_1	PF00076.22	1e-16	1	1
ENSP00000432595	RRM_1	PF00076.22	1e-16	1	1
ENSP00000403310	RRM_1	PF00076.22	1.1e-16	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000529201	SNRNP35-205	561	-	-	- (aa)	-	-
ENST00000412157	SNRNP35-202	1140	XM_017018724	ENSP00000403310	251 (aa)	XP_016874213	Q16560
ENST00000527158	SNRNP35-204	2161	NR_104103	-	- (aa)	-	-
ENST00000529904	SNRNP35-206	382	-	-	- (aa)	-	-
ENST00000350887	SNRNP35-201	942	XM_006719204	ENSP00000340774	246 (aa)	XP_006719267	Q16560
ENST00000526639	SNRNP35-203	1975	-	ENSP00000432595	246 (aa)	-	Q16560

Gene Model

Click here to download ENSG00000184209's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000184209's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000184209	SNRNP35	100	93.089	ENSAMEG00000019650	SNRNP35	100	93.117	Ailuropoda_melanoleuca
ENSG00000184209	SNRNP35	77	75.377	ENSACIG00000003238	snrnp35	80	84.118	Amphilophus_citrinellus
ENSG00000184209	SNRNP35	69	81.765	ENSAOCG00000007701	snrnp35	79	81.765	Amphiprion_ocellaris
ENSG00000184209	SNRNP35	77	76.316	ENSAPEG00000023725	snrnp35	80	81.765	Amphiprion_percula
ENSG00000184209	SNRNP35	69	81.176	ENSATEG00000021269	snrnp35	99	70.476	Anabas_testudineus
ENSG00000184209	SNRNP35	92	82.301	ENSAPLG00000015654	SNRNP35	90	82.301	Anas_platyrhynchos
ENSG00000184209	SNRNP35	89	81.364	ENSACAG00000015421	SNRNP35	92	77.459	Anolis_carolinensis
ENSG00000184209	SNRNP35	100	97.166	ENSANAG00000025109	SNRNP35	98	96.787	Aotus_nancymaae
ENSG00000184209	SNRNP35	69	83.529	ENSACLG00000020994	SNRNP35	81	83.529	Astatotilapia_calliptera
ENSG00000184209	SNRNP35	69	83.529	ENSACLG00000020890	snrnp35	81	83.529	Astatotilapia_calliptera
ENSG00000184209	SNRNP35	68	78.571	ENSAMXG00000026163	snrnp35	80	78.571	Astyanax_mexicanus
ENSG00000184209	SNRNP35	100	91.870	ENSBTAG00000008060	SNRNP35	100	91.870	Bos_taurus
ENSG00000184209	SNRNP35	100	96.813	ENSCJAG00000007131	SNRNP35	100	96.813	Callithrix_jacchus
ENSG00000184209	SNRNP35	100	92.276	ENSCAFG00000007484	SNRNP35	100	92.276	Canis_familiaris
ENSG00000184209	SNRNP35	100	92.276	ENSCAFG00020015272	-	100	92.276	Canis_lupus_dingo
ENSG00000184209	SNRNP35	100	91.463	ENSCHIG00000006364	SNRNP35	100	91.463	Capra_hircus
ENSG00000184209	SNRNP35	100	95.528	ENSTSYG00000034104	SNRNP35	100	95.547	Carlito_syrichta
ENSG00000184209	SNRNP35	100	89.837	ENSCPOG00000002548	SNRNP35	100	89.837	Cavia_porcellus
ENSG00000184209	SNRNP35	100	96.761	ENSCCAG00000001685	SNRNP35	100	96.429	Cebus_capucinus
ENSG00000184209	SNRNP35	100	98.374	ENSCATG00000021946	SNRNP35	100	98.381	Cercocebus_atys
ENSG00000184209	SNRNP35	100	90.244	ENSCLAG00000010232	SNRNP35	100	90.244	Chinchilla_lanigera
ENSG00000184209	SNRNP35	100	98.780	ENSCSAG00000018950	SNRNP35	100	98.780	Chlorocebus_sabaeus
ENSG00000184209	SNRNP35	100	93.496	ENSCHOG00000006263	SNRNP35	100	93.117	Choloepus_hoffmanni
ENSG00000184209	SNRNP35	97	77.311	ENSCPBG00000025965	SNRNP35	91	77.049	Chrysemys_picta_bellii
ENSG00000184209	SNRNP35	70	57.558	ENSCSAVG00000000748	-	96	57.558	Ciona_savignyi
ENSG00000184209	SNRNP35	100	98.374	ENSCANG00000025364	SNRNP35	100	98.008	Colobus_angolensis_palliatus
ENSG00000184209	SNRNP35	100	89.431	ENSCGRG00001012630	Snrnp35	100	89.431	Cricetulus_griseus_chok1gshd
ENSG00000184209	SNRNP35	100	89.431	ENSCGRG00000002063	Snrnp35	100	89.431	Cricetulus_griseus_crigri
ENSG00000184209	SNRNP35	67	76.506	ENSDARG00000099913	snrnp35	81	75.595	Danio_rerio
ENSG00000184209	SNRNP35	100	93.902	ENSDNOG00000038603	SNRNP35	100	93.902	Dasypus_novemcinctus
ENSG00000184209	SNRNP35	100	92.276	ENSDORG00000001859	Snrnp35	100	92.276	Dipodomys_ordii
ENSG00000184209	SNRNP35	68	60.119	ENSEBUG00000003535	snrnp35	64	59.412	Eptatretus_burgeri
ENSG00000184209	SNRNP35	99	95.082	ENSEASG00005012617	SNRNP35	99	95.082	Equus_asinus_asinus
ENSG00000184209	SNRNP35	99	95.082	ENSECAG00000006080	SNRNP35	99	95.082	Equus_caballus
ENSG00000184209	SNRNP35	80	94.924	ENSEEUG00000011544	SNRNP35	82	93.103	Erinaceus_europaeus
ENSG00000184209	SNRNP35	90	67.249	ENSELUG00000000071	snrnp35	71	82.456	Esox_lucius
ENSG00000184209	SNRNP35	100	93.902	ENSFCAG00000001159	SNRNP35	100	93.625	Felis_catus
ENSG00000184209	SNRNP35	99	78.279	ENSFALG00000014650	SNRNP35	99	78.279	Ficedula_albicollis
ENSG00000184209	SNRNP35	100	82.520	ENSFDAG00000018743	SNRNP35	100	81.707	Fukomys_damarensis
ENSG00000184209	SNRNP35	85	66.516	ENSGMOG00000002299	snrnp35	95	61.570	Gadus_morhua
ENSG00000184209	SNRNP35	97	78.151	ENSGALG00000003318	SNRNP35	90	77.869	Gallus_gallus
ENSG00000184209	SNRNP35	69	79.412	ENSGACG00000020631	snrnp35	97	65.041	Gasterosteus_aculeatus
ENSG00000184209	SNRNP35	100	99.602	ENSGGOG00000015936	SNRNP35	100	99.602	Gorilla_gorilla
ENSG00000184209	SNRNP35	85	72.986	ENSHBUG00000015853	snrnp35	80	83.529	Haplochromis_burtoni
ENSG00000184209	SNRNP35	100	91.057	ENSHGLG00000017961	SNRNP35	100	91.057	Heterocephalus_glaber_female
ENSG00000184209	SNRNP35	100	91.057	ENSHGLG00100019252	SNRNP35	100	91.057	Heterocephalus_glaber_male
ENSG00000184209	SNRNP35	70	74.269	ENSIPUG00000016053	snrnp35	65	74.269	Ictalurus_punctatus
ENSG00000184209	SNRNP35	100	88.211	ENSSTOG00000025145	SNRNP35	100	88.211	Ictidomys_tridecemlineatus
ENSG00000184209	SNRNP35	100	91.463	ENSJJAG00000013421	Snrnp35	97	91.463	Jaculus_jaculus
ENSG00000184209	SNRNP35	82	82.178	ENSLACG00000017176	SNRNP35	86	73.770	Latimeria_chalumnae
ENSG00000184209	SNRNP35	71	79.885	ENSLOCG00000018154	snrnp35	93	65.098	Lepisosteus_oculatus
ENSG00000184209	SNRNP35	100	93.089	ENSLAFG00000022302	SNRNP35	100	93.089	Loxodonta_africana
ENSG00000184209	SNRNP35	100	98.780	ENSMFAG00000008986	SNRNP35	100	98.785	Macaca_fascicularis
ENSG00000184209	SNRNP35	100	98.374	ENSMMUG00000008411	SNRNP35	100	98.381	Macaca_mulatta
ENSG00000184209	SNRNP35	100	98.780	ENSMNEG00000018139	SNRNP35	100	98.785	Macaca_nemestrina
ENSG00000184209	SNRNP35	100	98.374	ENSMLEG00000040998	SNRNP35	100	97.610	Mandrillus_leucophaeus
ENSG00000184209	SNRNP35	68	83.333	ENSMAMG00000018927	snrnp35	94	73.182	Mastacembelus_armatus
ENSG00000184209	SNRNP35	69	83.529	ENSMZEG00005018928	snrnp35	81	83.529	Maylandia_zebra
ENSG00000184209	SNRNP35	67	76.970	ENSMZEG00005018947	-	78	76.970	Maylandia_zebra
ENSG00000184209	SNRNP35	99	78.689	ENSMGAG00000003241	SNRNP35	99	78.689	Meleagris_gallopavo
ENSG00000184209	SNRNP35	100	90.244	ENSMAUG00000001690	Snrnp35	100	90.244	Mesocricetus_auratus
ENSG00000184209	SNRNP35	100	96.341	ENSMICG00000026512	SNRNP35	100	96.016	Microcebus_murinus
ENSG00000184209	SNRNP35	100	90.244	ENSMOCG00000000548	Snrnp35	100	90.244	Microtus_ochrogaster
ENSG00000184209	SNRNP35	69	81.765	ENSMMOG00000018779	snrnp35	94	71.622	Mola_mola
ENSG00000184209	SNRNP35	73	87.709	ENSMODG00000012481	SNRNP35	100	87.709	Monodelphis_domestica
ENSG00000184209	SNRNP35	100	89.024	MGP_CAROLIEiJ_G0027752	Snrnp35	100	96.694	Mus_caroli
ENSG00000184209	SNRNP35	100	89.024	ENSMUSG00000029402	Snrnp35	100	95.868	Mus_musculus
ENSG00000184209	SNRNP35	91	92.000	MGP_PahariEiJ_G0024332	Snrnp35	100	95.868	Mus_pahari
ENSG00000184209	SNRNP35	100	89.024	MGP_SPRETEiJ_G0028751	Snrnp35	100	95.868	Mus_spretus
ENSG00000184209	SNRNP35	100	92.276	ENSMPUG00000019392	SNRNP35	100	92.276	Mustela_putorius_furo
ENSG00000184209	SNRNP35	100	90.244	ENSMLUG00000025311	SNRNP35	100	90.244	Myotis_lucifugus
ENSG00000184209	SNRNP35	100	88.306	ENSNGAG00000010711	Snrnp35	100	88.306	Nannospalax_galili
ENSG00000184209	SNRNP35	100	100.000	ENSNLEG00000029859	SNRNP35	100	100.000	Nomascus_leucogenys
ENSG00000184209	SNRNP35	100	90.650	ENSOPRG00000011119	SNRNP35	100	90.283	Ochotona_princeps
ENSG00000184209	SNRNP35	100	90.650	ENSODEG00000019870	SNRNP35	100	90.650	Octodon_degus
ENSG00000184209	SNRNP35	79	72.464	ENSONIG00000021361	snrnp35	95	70.485	Oreochromis_niloticus
ENSG00000184209	SNRNP35	96	81.328	ENSOANG00000002697	SNRNP35	100	81.481	Ornithorhynchus_anatinus
ENSG00000184209	SNRNP35	100	90.650	ENSOCUG00000021248	SNRNP35	100	90.650	Oryctolagus_cuniculus
ENSG00000184209	SNRNP35	76	75.916	ENSORLG00000005673	snrnp35	79	82.143	Oryzias_latipes
ENSG00000184209	SNRNP35	76	76.440	ENSORLG00015014439	snrnp35	82	82.738	Oryzias_latipes_hsok
ENSG00000184209	SNRNP35	100	95.122	ENSOGAG00000011301	SNRNP35	100	95.122	Otolemur_garnettii
ENSG00000184209	SNRNP35	100	91.463	ENSOARG00000004583	SNRNP35	100	91.463	Ovis_aries
ENSG00000184209	SNRNP35	100	99.602	ENSPPAG00000000480	SNRNP35	100	99.602	Pan_paniscus
ENSG00000184209	SNRNP35	100	93.496	ENSPPRG00000013139	SNRNP35	100	93.227	Panthera_pardus
ENSG00000184209	SNRNP35	100	93.496	ENSPTIG00000015832	SNRNP35	100	92.829	Panthera_tigris_altaica
ENSG00000184209	SNRNP35	100	99.602	ENSPTRG00000023573	SNRNP35	100	99.602	Pan_troglodytes
ENSG00000184209	SNRNP35	100	98.374	ENSPANG00000019739	SNRNP35	100	97.610	Papio_anubis
ENSG00000184209	SNRNP35	74	75.824	ENSPKIG00000005221	snrnp35	81	79.882	Paramormyrops_kingsleyae
ENSG00000184209	SNRNP35	99	78.279	ENSPSIG00000000450	SNRNP35	91	78.279	Pelodiscus_sinensis
ENSG00000184209	SNRNP35	89	83.636	ENSPCIG00000010978	SNRNP35	92	80.328	Phascolarctos_cinereus
ENSG00000184209	SNRNP35	68	84.524	ENSPFOG00000019881	snrnp35	76	84.524	Poecilia_formosa
ENSG00000184209	SNRNP35	100	100.000	ENSPPYG00000005088	SNRNP35	100	100.000	Pongo_abelii
ENSG00000184209	SNRNP35	100	90.650	ENSPCAG00000011478	SNRNP35	99	90.650	Procavia_capensis
ENSG00000184209	SNRNP35	100	95.935	ENSPCOG00000009946	SNRNP35	100	95.951	Propithecus_coquereli
ENSG00000184209	SNRNP35	100	92.276	ENSPVAG00000015317	SNRNP35	100	92.308	Pteropus_vampyrus
ENSG00000184209	SNRNP35	99	63.347	ENSPNAG00000020589	snrnp35	96	62.500	Pygocentrus_nattereri
ENSG00000184209	SNRNP35	100	89.024	ENSRNOG00000001060	Snrnp35	100	89.024	Rattus_norvegicus
ENSG00000184209	SNRNP35	100	98.780	ENSRBIG00000043111	SNRNP35	100	98.008	Rhinopithecus_bieti
ENSG00000184209	SNRNP35	100	98.780	ENSRROG00000032878	SNRNP35	100	98.008	Rhinopithecus_roxellana
ENSG00000184209	SNRNP35	100	97.222	ENSSBOG00000012231	SNRNP35	100	97.222	Saimiri_boliviensis_boliviensis
ENSG00000184209	SNRNP35	94	80.519	ENSSHAG00000001216	-	99	77.869	Sarcophilus_harrisii
ENSG00000184209	SNRNP35	89	83.636	ENSSHAG00000015558	-	99	79.918	Sarcophilus_harrisii
ENSG00000184209	SNRNP35	72	77.966	ENSSFOG00015003785	snrnp35	95	77.966	Scleropages_formosus
ENSG00000184209	SNRNP35	79	73.846	ENSSLDG00000017209	snrnp35	80	81.765	Seriola_lalandi_dorsalis
ENSG00000184209	SNRNP35	100	85.772	ENSSARG00000012656	SNRNP35	100	85.830	Sorex_araneus
ENSG00000184209	SNRNP35	96	75.319	ENSSPUG00000012768	SNRNP35	92	74.590	Sphenodon_punctatus
ENSG00000184209	SNRNP35	87	70.233	ENSSPAG00000008207	snrnp35	79	81.176	Stegastes_partitus
ENSG00000184209	SNRNP35	100	91.463	ENSSSCG00000022212	SNRNP35	99	92.925	Sus_scrofa
ENSG00000184209	SNRNP35	97	77.731	ENSTGUG00000015471	-	91	77.459	Taeniopygia_guttata
ENSG00000184209	SNRNP35	99	77.869	ENSTGUG00000005364	-	99	77.869	Taeniopygia_guttata
ENSG00000184209	SNRNP35	68	82.143	ENSTNIG00000009984	snrnp35	80	82.143	Tetraodon_nigroviridis
ENSG00000184209	SNRNP35	100	92.276	ENSTBEG00000002309	SNRNP35	99	92.276	Tupaia_belangeri
ENSG00000184209	SNRNP35	100	93.902	ENSUAMG00000012611	SNRNP35	100	93.902	Ursus_americanus
ENSG00000184209	SNRNP35	100	93.902	ENSUMAG00000003914	SNRNP35	98	93.200	Ursus_maritimus
ENSG00000184209	SNRNP35	100	92.276	ENSVVUG00000027761	-	100	92.276	Vulpes_vulpes
ENSG00000184209	SNRNP35	68	84.524	ENSXMAG00000019885	snrnp35	67	84.524	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000398	mRNA splicing, via spliceosome	21873635.	IBA	Process
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0003729	mRNA binding	21873635.	IBA	Function
GO:0005634	nucleus	18559850.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005689	U12-type spliceosomal complex	21873635.	IBA	Component
GO:0005689	U12-type spliceosomal complex	15146077.	IDA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0008380	RNA splicing	15146077.	IC	Process