EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000184677 (Gene tree)
Gene ID: 9923
Gene Symbol: ZBTB40
Alias: KIAA0478|ZNF923
Full Name: zinc finger and BTB domain containing 40
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 102,320 bases
Position: chr1:22,428,838-22,531,157
Accession: 29045
RBP type: canonical RBP
Summary: ZBTB40 (Zinc Finger And BTB Domain Containing 40) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000364798	zf-C2H2	PF00096.26	1.4e-33	1	4
ENSP00000364798	zf-C2H2	PF00096.26	1.4e-33	2	4
ENSP00000364798	zf-C2H2	PF00096.26	1.4e-33	3	4
ENSP00000364798	zf-C2H2	PF00096.26	1.4e-33	4	4
ENSP00000384527	zf-C2H2	PF00096.26	1.4e-33	1	4
ENSP00000384527	zf-C2H2	PF00096.26	1.4e-33	2	4
ENSP00000384527	zf-C2H2	PF00096.26	1.4e-33	3	4
ENSP00000384527	zf-C2H2	PF00096.26	1.4e-33	4	4
ENSP00000363782	zf-C2H2	PF00096.26	2e-32	1	4
ENSP00000363782	zf-C2H2	PF00096.26	2e-32	2	4
ENSP00000363782	zf-C2H2	PF00096.26	2e-32	3	4
ENSP00000363782	zf-C2H2	PF00096.26	2e-32	4	4
ENSP00000363782	zf-met	PF12874.7	1.4e-05	1	1
ENSP00000364798	zf-met	PF12874.7	3.9e-05	1	1
ENSP00000384527	zf-met	PF12874.7	3.9e-05	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000374651	ZBTB40-201	8368	XM_011542500	ENSP00000363782	1127 (aa)	XP_011540802	F8WAI8
ENST00000375647	ZBTB40-202	8685	XM_011542499	ENSP00000364798	1239 (aa)	XP_011540801	Q9NUA8
ENST00000404138	ZBTB40-204	8992	-	ENSP00000384527	1239 (aa)	-	Q9NUA8
ENST00000650433	ZBTB40-205	2000	-	ENSP00000496988	584 (aa)	-	-
ENST00000400239	ZBTB40-203	1855	-	ENSP00000383098	453 (aa)	-	B1AKC8

Gene Model

Click here to download ENSG00000184677's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000184677	Heart Failure	1.5623436E-004	-
ENSG00000184677	Platelet Function Tests	3.3800000E-007	-
ENSG00000184677	Platelet Function Tests	5.1600000E-007	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000184677	rs61769193	1	22453334	?	Eosinophil counts	30595370			EFO_0004842

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000184677's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000184677	ZBTB40	100	84.464	ENSAMEG00000014635	ZBTB40	100	84.464	Ailuropoda_melanoleuca
ENSG00000184677	ZBTB40	100	94.425	ENSANAG00000010550	ZBTB40	100	94.425	Aotus_nancymaae
ENSG00000184677	ZBTB40	100	83.616	ENSBTAG00000016448	ZBTB40	100	83.616	Bos_taurus
ENSG00000184677	ZBTB40	100	94.071	ENSCJAG00000005869	ZBTB40	100	94.071	Callithrix_jacchus
ENSG00000184677	ZBTB40	100	86.082	ENSCAFG00000014644	ZBTB40	100	86.082	Canis_familiaris
ENSG00000184677	ZBTB40	100	86.118	ENSCAFG00020019562	ZBTB40	100	86.118	Canis_lupus_dingo
ENSG00000184677	ZBTB40	100	83.119	ENSCHIG00000007943	ZBTB40	100	83.119	Capra_hircus
ENSG00000184677	ZBTB40	100	87.379	ENSTSYG00000000979	ZBTB40	100	87.379	Carlito_syrichta
ENSG00000184677	ZBTB40	100	83.378	ENSCAPG00000009177	ZBTB40	100	83.378	Cavia_aperea
ENSG00000184677	ZBTB40	100	87.748	ENSCPOG00000012844	ZBTB40	100	87.748	Cavia_porcellus
ENSG00000184677	ZBTB40	100	93.805	ENSCCAG00000021093	ZBTB40	100	93.805	Cebus_capucinus
ENSG00000184677	ZBTB40	100	96.539	ENSCATG00000031739	ZBTB40	100	96.539	Cercocebus_atys
ENSG00000184677	ZBTB40	100	86.335	ENSCLAG00000015032	ZBTB40	100	86.335	Chinchilla_lanigera
ENSG00000184677	ZBTB40	100	96.368	ENSCSAG00000000911	ZBTB40	100	96.368	Chlorocebus_sabaeus
ENSG00000184677	ZBTB40	100	94.253	ENSCHOG00000011197	ZBTB40	93	94.253	Choloepus_hoffmanni
ENSG00000184677	ZBTB40	100	96.894	ENSCANG00000038636	ZBTB40	100	96.894	Colobus_angolensis_palliatus
ENSG00000184677	ZBTB40	100	80.385	ENSCGRG00001016016	Zbtb40	100	80.385	Cricetulus_griseus_chok1gshd
ENSG00000184677	ZBTB40	99	82.670	ENSCGRG00000008459	Zbtb40	99	82.670	Cricetulus_griseus_crigri
ENSG00000184677	ZBTB40	100	38.481	ENSDARG00000091762	zbtb40	100	38.913	Danio_rerio
ENSG00000184677	ZBTB40	100	86.795	ENSDNOG00000006200	ZBTB40	100	86.795	Dasypus_novemcinctus
ENSG00000184677	ZBTB40	100	84.867	ENSDORG00000016495	Zbtb40	100	84.867	Dipodomys_ordii
ENSG00000184677	ZBTB40	100	86.160	ENSEASG00005007270	ZBTB40	100	86.240	Equus_asinus_asinus
ENSG00000184677	ZBTB40	99	85.588	ENSECAG00000016319	ZBTB40	99	85.182	Equus_caballus
ENSG00000184677	ZBTB40	83	81.420	ENSEEUG00000001708	ZBTB40	100	81.977	Erinaceus_europaeus
ENSG00000184677	ZBTB40	100	87.522	ENSFCAG00000028182	ZBTB40	100	87.522	Felis_catus
ENSG00000184677	ZBTB40	100	83.865	ENSFDAG00000003410	ZBTB40	100	83.865	Fukomys_damarensis
ENSG00000184677	ZBTB40	100	98.846	ENSGGOG00000010010	ZBTB40	100	98.846	Gorilla_gorilla
ENSG00000184677	ZBTB40	100	81.278	ENSHGLG00000016950	ZBTB40	95	75.840	Heterocephalus_glaber_female
ENSG00000184677	ZBTB40	100	81.278	ENSHGLG00100008314	ZBTB40	95	75.840	Heterocephalus_glaber_male
ENSG00000184677	ZBTB40	100	87.165	ENSSTOG00000009598	ZBTB40	100	87.165	Ictidomys_tridecemlineatus
ENSG00000184677	ZBTB40	100	80.732	ENSJJAG00000018013	Zbtb40	100	81.858	Jaculus_jaculus
ENSG00000184677	ZBTB40	100	86.819	ENSLAFG00000006483	ZBTB40	100	86.819	Loxodonta_africana
ENSG00000184677	ZBTB40	100	96.451	ENSMFAG00000043032	ZBTB40	100	96.451	Macaca_fascicularis
ENSG00000184677	ZBTB40	100	96.362	ENSMMUG00000018618	ZBTB40	100	96.362	Macaca_mulatta
ENSG00000184677	ZBTB40	100	96.451	ENSMNEG00000032628	ZBTB40	100	96.451	Macaca_nemestrina
ENSG00000184677	ZBTB40	100	96.628	ENSMLEG00000027910	ZBTB40	100	96.628	Mandrillus_leucophaeus
ENSG00000184677	ZBTB40	100	79.728	ENSMAUG00000010466	Zbtb40	100	79.728	Mesocricetus_auratus
ENSG00000184677	ZBTB40	100	92.865	ENSMICG00000007464	ZBTB40	100	90.009	Microcebus_murinus
ENSG00000184677	ZBTB40	100	82.452	ENSMOCG00000013259	Zbtb40	100	81.993	Microtus_ochrogaster
ENSG00000184677	ZBTB40	100	77.948	MGP_CAROLIEiJ_G0026672	Zbtb40	100	77.948	Mus_caroli
ENSG00000184677	ZBTB40	100	77.972	ENSMUSG00000060862	Zbtb40	99	96.269	Mus_musculus
ENSG00000184677	ZBTB40	100	78.603	MGP_PahariEiJ_G0029005	Zbtb40	100	78.603	Mus_pahari
ENSG00000184677	ZBTB40	100	78.057	MGP_SPRETEiJ_G0027652	Zbtb40	100	78.057	Mus_spretus
ENSG00000184677	ZBTB40	100	83.736	ENSMPUG00000015961	ZBTB40	100	83.736	Mustela_putorius_furo
ENSG00000184677	ZBTB40	100	80.110	ENSNGAG00000019354	Zbtb40	100	80.110	Nannospalax_galili
ENSG00000184677	ZBTB40	100	97.516	ENSNLEG00000008268	ZBTB40	100	97.516	Nomascus_leucogenys
ENSG00000184677	ZBTB40	100	81.910	ENSOPRG00000003103	ZBTB40	95	84.205	Ochotona_princeps
ENSG00000184677	ZBTB40	100	86.620	ENSOGAG00000004797	ZBTB40	100	86.620	Otolemur_garnettii
ENSG00000184677	ZBTB40	100	82.878	ENSOARG00000008054	ZBTB40	100	83.427	Ovis_aries
ENSG00000184677	ZBTB40	100	98.580	ENSPPAG00000034112	ZBTB40	100	98.580	Pan_paniscus
ENSG00000184677	ZBTB40	100	86.903	ENSPPRG00000021468	ZBTB40	100	86.903	Panthera_pardus
ENSG00000184677	ZBTB40	100	86.726	ENSPTIG00000010874	ZBTB40	100	86.726	Panthera_tigris_altaica
ENSG00000184677	ZBTB40	100	98.580	ENSPTRG00000000315	ZBTB40	100	98.580	Pan_troglodytes
ENSG00000184677	ZBTB40	100	96.539	ENSPANG00000018749	ZBTB40	100	96.539	Papio_anubis
ENSG00000184677	ZBTB40	100	81.448	ENSPEMG00000009389	Zbtb40	100	81.448	Peromyscus_maniculatus_bairdii
ENSG00000184677	ZBTB40	100	76.313	ENSPCIG00000026425	ZBTB40	100	76.313	Phascolarctos_cinereus
ENSG00000184677	ZBTB40	100	97.902	ENSPPYG00000001752	ZBTB40	100	97.902	Pongo_abelii
ENSG00000184677	ZBTB40	100	97.714	ENSPCOG00000006905	ZBTB40	100	97.714	Propithecus_coquereli
ENSG00000184677	ZBTB40	100	77.948	ENSRNOG00000022039	Zbtb40	100	77.948	Rattus_norvegicus
ENSG00000184677	ZBTB40	100	96.451	ENSRBIG00000034608	ZBTB40	100	96.451	Rhinopithecus_bieti
ENSG00000184677	ZBTB40	100	96.539	ENSRROG00000034514	ZBTB40	100	96.539	Rhinopithecus_roxellana
ENSG00000184677	ZBTB40	100	93.894	ENSSBOG00000027235	ZBTB40	100	93.894	Saimiri_boliviensis_boliviensis
ENSG00000184677	ZBTB40	100	86.637	ENSUAMG00000020372	ZBTB40	100	86.637	Ursus_americanus
ENSG00000184677	ZBTB40	100	86.903	ENSUMAG00000013539	ZBTB40	100	86.903	Ursus_maritimus
ENSG00000184677	ZBTB40	100	86.030	ENSVVUG00000025752	ZBTB40	100	86.030	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0003674	molecular_function	-	ND	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	15302935.	IDA	Component
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0006974	cellular response to DNA damage stimulus	21873635.	IBA	Process
GO:0006974	cellular response to DNA damage stimulus	17525332.	IDA	Process
GO:0030282	bone mineralization	20554715.	NAS	Process
GO:0046872	metal ion binding	-	IEA	Function