EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000184967 (Gene tree)
Gene ID: 79050
Gene Symbol: NOC4L
Alias: MGC3162|NET49|UTP19|Noc4
Full Name: nucleolar complex associated 4 homolog
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 8,052 bases
Position: chr12:132,144,422-132,152,473
Accession: 28461
RBP type: canonical RBP
Summary: (Nucleolar Complex Associated 4 Homolog) is a Protein Coding gene. Among its related pathways are rRNA processing in the nucleus and cytosol and Gene Expression. Gene Ontology (GO) annotations related to this gene include binding.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000328854	CBF	PF03914.17	6.9e-38	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000535343	NOC4L-202	669	-	-	- (aa)	-	-
ENST00000330579	NOC4L-201	1632	XM_017019960	ENSP00000328854	516 (aa)	XP_016875449	Q9BVI4
ENST00000541954	NOC4L-204	1009	-	ENSP00000438255	270 (aa)	-	F5H303
ENST00000538784	NOC4L-203	862	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000184967's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000184967's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000184967	NOC4L	99	56.395	ENSAPOG00000007239	noc4l	97	56.395	Acanthochromis_polyacanthus
ENSG00000184967	NOC4L	99	80.739	ENSAMEG00000013649	NOC4L	99	80.739	Ailuropoda_melanoleuca
ENSG00000184967	NOC4L	99	55.837	ENSACIG00000009221	noc4l	89	55.837	Amphilophus_citrinellus
ENSG00000184967	NOC4L	99	56.008	ENSAOCG00000022225	noc4l	97	56.008	Amphiprion_ocellaris
ENSG00000184967	NOC4L	99	56.117	ENSAPEG00000005789	noc4l	96	57.469	Amphiprion_percula
ENSG00000184967	NOC4L	99	55.922	ENSATEG00000020704	noc4l	97	56.031	Anabas_testudineus
ENSG00000184967	NOC4L	85	60.045	ENSAPLG00000001340	NOC4L	99	60.045	Anas_platyrhynchos
ENSG00000184967	NOC4L	99	58.949	ENSACAG00000007479	NOC4L	93	58.949	Anolis_carolinensis
ENSG00000184967	NOC4L	100	92.054	ENSANAG00000035196	NOC4L	100	92.054	Aotus_nancymaae
ENSG00000184967	NOC4L	99	55.922	ENSACLG00000020832	noc4l	97	55.922	Astatotilapia_calliptera
ENSG00000184967	NOC4L	99	55.233	ENSAMXG00000008720	noc4l	98	55.233	Astyanax_mexicanus
ENSG00000184967	NOC4L	100	84.496	ENSBTAG00000011889	NOC4L	100	84.496	Bos_taurus
ENSG00000184967	NOC4L	50	35.249	WBGene00020601	T20B12.3	52	35.249	Caenorhabditis_elegans
ENSG00000184967	NOC4L	94	92.547	ENSCJAG00000005405	NOC4L	89	92.547	Callithrix_jacchus
ENSG00000184967	NOC4L	100	81.008	ENSCAFG00000006300	NOC4L	100	81.008	Canis_familiaris
ENSG00000184967	NOC4L	100	81.008	ENSCAFG00020010316	NOC4L	100	81.008	Canis_lupus_dingo
ENSG00000184967	NOC4L	100	82.567	ENSCHIG00000007775	NOC4L	100	82.567	Capra_hircus
ENSG00000184967	NOC4L	89	83.843	ENSTSYG00000025452	NOC4L	96	83.843	Carlito_syrichta
ENSG00000184967	NOC4L	84	81.881	ENSCAPG00000011665	NOC4L	100	81.881	Cavia_aperea
ENSG00000184967	NOC4L	100	81.977	ENSCPOG00000021166	NOC4L	100	81.977	Cavia_porcellus
ENSG00000184967	NOC4L	100	90.504	ENSCCAG00000029963	NOC4L	100	90.504	Cebus_capucinus
ENSG00000184967	NOC4L	100	96.705	ENSCATG00000035699	NOC4L	100	96.705	Cercocebus_atys
ENSG00000184967	NOC4L	100	82.171	ENSCLAG00000007550	NOC4L	100	82.171	Chinchilla_lanigera
ENSG00000184967	NOC4L	100	96.512	ENSCSAG00000001865	NOC4L	100	96.512	Chlorocebus_sabaeus
ENSG00000184967	NOC4L	96	64.529	ENSCPBG00000024642	NOC4L	99	63.619	Chrysemys_picta_bellii
ENSG00000184967	NOC4L	97	35.659	ENSCING00000011753	-	98	35.659	Ciona_intestinalis
ENSG00000184967	NOC4L	100	90.698	ENSCANG00000037218	NOC4L	100	90.698	Colobus_angolensis_palliatus
ENSG00000184967	NOC4L	100	80.039	ENSCGRG00001004291	Noc4l	100	80.039	Cricetulus_griseus_chok1gshd
ENSG00000184967	NOC4L	95	81.224	ENSCGRG00000005706	Noc4l	100	81.059	Cricetulus_griseus_crigri
ENSG00000184967	NOC4L	99	54.492	ENSCSEG00000003635	noc4l	97	54.492	Cynoglossus_semilaevis
ENSG00000184967	NOC4L	99	54.864	ENSCVAG00000000047	noc4l	98	54.864	Cyprinodon_variegatus
ENSG00000184967	NOC4L	99	54.688	ENSDARG00000045565	noc4l	97	54.688	Danio_rerio
ENSG00000184967	NOC4L	98	85.455	ENSDNOG00000041813	NOC4L	84	86.473	Dasypus_novemcinctus
ENSG00000184967	NOC4L	99	81.553	ENSDORG00000015155	Noc4l	99	81.553	Dipodomys_ordii
ENSG00000184967	NOC4L	72	30.851	FBgn0029672	CG2875	73	30.585	Drosophila_melanogaster
ENSG00000184967	NOC4L	78	78.304	ENSETEG00000006237	NOC4L	100	78.304	Echinops_telfairi
ENSG00000184967	NOC4L	83	47.674	ENSEBUG00000001980	noc4l	94	47.674	Eptatretus_burgeri
ENSG00000184967	NOC4L	100	83.748	ENSEASG00005016651	NOC4L	100	83.748	Equus_asinus_asinus
ENSG00000184967	NOC4L	100	83.915	ENSECAG00000024217	NOC4L	100	83.915	Equus_caballus
ENSG00000184967	NOC4L	99	56.589	ENSELUG00000010483	noc4l	97	56.589	Esox_lucius
ENSG00000184967	NOC4L	100	85.300	ENSFCAG00000010783	NOC4L	100	85.300	Felis_catus
ENSG00000184967	NOC4L	82	61.124	ENSFALG00000008259	NOC4L	100	61.124	Ficedula_albicollis
ENSG00000184967	NOC4L	99	78.125	ENSFDAG00000001178	NOC4L	99	79.757	Fukomys_damarensis
ENSG00000184967	NOC4L	99	56.226	ENSFHEG00000010492	noc4l	98	56.226	Fundulus_heteroclitus
ENSG00000184967	NOC4L	97	56.886	ENSGMOG00000003087	noc4l	95	56.886	Gadus_morhua
ENSG00000184967	NOC4L	98	58.465	ENSGALG00000002272	NOC4L	99	58.465	Gallus_gallus
ENSG00000184967	NOC4L	99	54.386	ENSGAFG00000006565	noc4l	94	54.386	Gambusia_affinis
ENSG00000184967	NOC4L	99	55.426	ENSGACG00000017577	noc4l	98	56.557	Gasterosteus_aculeatus
ENSG00000184967	NOC4L	96	60.362	ENSGAGG00000016459	NOC4L	99	63.248	Gopherus_agassizii
ENSG00000184967	NOC4L	100	98.643	ENSGGOG00000010266	NOC4L	100	98.643	Gorilla_gorilla
ENSG00000184967	NOC4L	99	56.699	ENSHBUG00000001312	noc4l	97	56.699	Haplochromis_burtoni
ENSG00000184967	NOC4L	100	83.527	ENSHGLG00000011672	NOC4L	100	83.527	Heterocephalus_glaber_female
ENSG00000184967	NOC4L	100	83.527	ENSHGLG00100017890	NOC4L	100	83.527	Heterocephalus_glaber_male
ENSG00000184967	NOC4L	99	53.696	ENSHCOG00000014284	noc4l	97	53.696	Hippocampus_comes
ENSG00000184967	NOC4L	99	57.004	ENSIPUG00000010363	noc4l	97	57.004	Ictalurus_punctatus
ENSG00000184967	NOC4L	97	83.234	ENSSTOG00000022612	NOC4L	97	83.234	Ictidomys_tridecemlineatus
ENSG00000184967	NOC4L	100	79.070	ENSJJAG00000020377	Noc4l	100	79.070	Jaculus_jaculus
ENSG00000184967	NOC4L	97	56.487	ENSKMAG00000012718	noc4l	95	56.487	Kryptolebias_marmoratus
ENSG00000184967	NOC4L	97	55.621	ENSLBEG00000002825	noc4l	95	55.621	Labrus_bergylta
ENSG00000184967	NOC4L	99	55.985	ENSLACG00000018559	NOC4L	99	55.985	Latimeria_chalumnae
ENSG00000184967	NOC4L	98	58.580	ENSLOCG00000006060	noc4l	95	58.580	Lepisosteus_oculatus
ENSG00000184967	NOC4L	97	80.915	ENSLAFG00000027295	NOC4L	100	79.651	Loxodonta_africana
ENSG00000184967	NOC4L	100	96.512	ENSMFAG00000046313	NOC4L	100	96.512	Macaca_fascicularis
ENSG00000184967	NOC4L	100	96.124	ENSMMUG00000006735	NOC4L	100	96.124	Macaca_mulatta
ENSG00000184967	NOC4L	100	96.899	ENSMNEG00000043745	NOC4L	100	96.899	Macaca_nemestrina
ENSG00000184967	NOC4L	92	96.855	ENSMLEG00000032574	NOC4L	100	96.855	Mandrillus_leucophaeus
ENSG00000184967	NOC4L	99	55.728	ENSMAMG00000007207	noc4l	97	55.728	Mastacembelus_armatus
ENSG00000184967	NOC4L	99	55.922	ENSMZEG00005017749	noc4l	97	55.922	Maylandia_zebra
ENSG00000184967	NOC4L	71	59.128	ENSMGAG00000001901	NOC4L	100	59.128	Meleagris_gallopavo
ENSG00000184967	NOC4L	100	78.876	ENSMAUG00000018153	Noc4l	100	78.876	Mesocricetus_auratus
ENSG00000184967	NOC4L	100	85.271	ENSMICG00000011789	NOC4L	96	85.271	Microcebus_murinus
ENSG00000184967	NOC4L	100	72.093	ENSMOCG00000022696	-	100	72.093	Microtus_ochrogaster
ENSG00000184967	NOC4L	100	77.132	ENSMOCG00000015072	-	100	77.132	Microtus_ochrogaster
ENSG00000184967	NOC4L	93	72.765	ENSMODG00000015342	NOC4L	100	72.765	Monodelphis_domestica
ENSG00000184967	NOC4L	97	57.030	ENSMALG00000013174	noc4l	95	57.030	Monopterus_albus
ENSG00000184967	NOC4L	100	77.907	MGP_CAROLIEiJ_G0027548	Noc4l	100	77.907	Mus_caroli
ENSG00000184967	NOC4L	100	79.070	ENSMUSG00000033294	Noc4l	100	79.070	Mus_musculus
ENSG00000184967	NOC4L	99	78.447	MGP_PahariEiJ_G0024130	Noc4l	100	78.295	Mus_pahari
ENSG00000184967	NOC4L	100	79.070	MGP_SPRETEiJ_G0028546	Noc4l	100	79.070	Mus_spretus
ENSG00000184967	NOC4L	85	80.909	ENSMPUG00000002415	NOC4L	99	80.822	Mustela_putorius_furo
ENSG00000184967	NOC4L	100	81.609	ENSMLUG00000028195	NOC4L	100	81.609	Myotis_lucifugus
ENSG00000184967	NOC4L	100	79.264	ENSNGAG00000002758	Noc4l	100	79.264	Nannospalax_galili
ENSG00000184967	NOC4L	99	55.728	ENSNBRG00000020542	noc4l	97	55.728	Neolamprologus_brichardi
ENSG00000184967	NOC4L	100	88.411	ENSNLEG00000008553	NOC4L	100	88.411	Nomascus_leucogenys
ENSG00000184967	NOC4L	84	75.000	ENSMEUG00000004020	NOC4L	86	71.978	Notamacropus_eugenii
ENSG00000184967	NOC4L	59	80.921	ENSOPRG00000012976	-	99	80.921	Ochotona_princeps
ENSG00000184967	NOC4L	98	81.423	ENSODEG00000007796	NOC4L	99	81.423	Octodon_degus
ENSG00000184967	NOC4L	99	56.699	ENSONIG00000003800	noc4l	97	56.699	Oreochromis_niloticus
ENSG00000184967	NOC4L	83	67.898	ENSOANG00000007306	NOC4L	99	67.898	Ornithorhynchus_anatinus
ENSG00000184967	NOC4L	97	54.491	ENSORLG00000010804	noc4l	94	54.491	Oryzias_latipes
ENSG00000184967	NOC4L	97	54.691	ENSORLG00020000286	noc4l	94	54.691	Oryzias_latipes_hni
ENSG00000184967	NOC4L	97	50.696	ENSORLG00015023020	noc4l	93	50.696	Oryzias_latipes_hsok
ENSG00000184967	NOC4L	99	54.951	ENSOMEG00000022646	noc4l	96	54.951	Oryzias_melastigma
ENSG00000184967	NOC4L	100	85.853	ENSOGAG00000001727	NOC4L	99	85.853	Otolemur_garnettii
ENSG00000184967	NOC4L	100	84.884	ENSOARG00000011688	NOC4L	95	84.884	Ovis_aries
ENSG00000184967	NOC4L	99	98.450	ENSPPAG00000042504	NOC4L	100	99.402	Pan_paniscus
ENSG00000184967	NOC4L	100	84.913	ENSPPRG00000014742	NOC4L	100	84.913	Panthera_pardus
ENSG00000184967	NOC4L	100	98.837	ENSPTRG00000050596	NOC4L	100	98.837	Pan_troglodytes
ENSG00000184967	NOC4L	100	96.705	ENSPANG00000011004	NOC4L	100	96.705	Papio_anubis
ENSG00000184967	NOC4L	98	54.028	ENSPKIG00000017628	noc4l	96	54.028	Paramormyrops_kingsleyae
ENSG00000184967	NOC4L	82	64.789	ENSPSIG00000007614	NOC4L	99	64.789	Pelodiscus_sinensis
ENSG00000184967	NOC4L	97	54.800	ENSPMGG00000004587	noc4l	94	53.800	Periophthalmus_magnuspinnatus
ENSG00000184967	NOC4L	100	78.723	ENSPEMG00000011021	Noc4l	100	78.723	Peromyscus_maniculatus_bairdii
ENSG00000184967	NOC4L	99	70.077	ENSPCIG00000004756	NOC4L	99	70.077	Phascolarctos_cinereus
ENSG00000184967	NOC4L	99	53.801	ENSPFOG00000019666	noc4l	98	53.801	Poecilia_formosa
ENSG00000184967	NOC4L	85	54.425	ENSPLAG00000002727	-	92	54.425	Poecilia_latipinna
ENSG00000184967	NOC4L	99	53.996	ENSPLAG00000007196	noc4l	98	53.996	Poecilia_latipinna
ENSG00000184967	NOC4L	99	38.662	ENSPMEG00000011164	-	99	52.805	Poecilia_mexicana
ENSG00000184967	NOC4L	99	53.801	ENSPMEG00000006050	noc4l	98	53.801	Poecilia_mexicana
ENSG00000184967	NOC4L	97	54.890	ENSPREG00000007187	noc4l	95	54.890	Poecilia_reticulata
ENSG00000184967	NOC4L	88	80.088	ENSPPYG00000005136	-	92	79.646	Pongo_abelii
ENSG00000184967	NOC4L	100	73.256	ENSPCAG00000009845	NOC4L	100	73.256	Procavia_capensis
ENSG00000184967	NOC4L	100	86.240	ENSPCOG00000020675	NOC4L	100	86.240	Propithecus_coquereli
ENSG00000184967	NOC4L	78	78.022	ENSPVAG00000000458	NOC4L	71	78.022	Pteropus_vampyrus
ENSG00000184967	NOC4L	99	55.922	ENSPNYG00000013588	noc4l	97	55.922	Pundamilia_nyererei
ENSG00000184967	NOC4L	98	55.819	ENSPNAG00000025632	noc4l	96	55.819	Pygocentrus_nattereri
ENSG00000184967	NOC4L	100	78.682	ENSRNOG00000037478	Noc4l	100	78.682	Rattus_norvegicus
ENSG00000184967	NOC4L	100	95.736	ENSRBIG00000037584	NOC4L	100	95.736	Rhinopithecus_bieti
ENSG00000184967	NOC4L	100	95.736	ENSRROG00000033324	NOC4L	100	95.736	Rhinopithecus_roxellana
ENSG00000184967	NOC4L	87	31.653	YPR144C	NOC4	87	31.250	Saccharomyces_cerevisiae
ENSG00000184967	NOC4L	90	93.133	ENSSBOG00000031768	NOC4L	100	93.133	Saimiri_boliviensis_boliviensis
ENSG00000184967	NOC4L	93	72.141	ENSSHAG00000011598	NOC4L	100	72.141	Sarcophilus_harrisii
ENSG00000184967	NOC4L	92	58.159	ENSSFOG00015000842	noc4l	88	58.159	Scleropages_formosus
ENSG00000184967	NOC4L	97	56.040	ENSSMAG00000019065	noc4l	95	56.040	Scophthalmus_maximus
ENSG00000184967	NOC4L	99	55.922	ENSSDUG00000007110	noc4l	97	55.922	Seriola_dumerili
ENSG00000184967	NOC4L	99	55.728	ENSSLDG00000022859	noc4l	97	55.728	Seriola_lalandi_dorsalis
ENSG00000184967	NOC4L	97	63.800	ENSSPUG00000009730	NOC4L	99	62.913	Sphenodon_punctatus
ENSG00000184967	NOC4L	99	55.319	ENSSPAG00000006316	noc4l	97	55.319	Stegastes_partitus
ENSG00000184967	NOC4L	100	82.320	ENSSSCG00000009739	NOC4L	100	86.848	Sus_scrofa
ENSG00000184967	NOC4L	97	59.163	ENSTGUG00000008115	-	98	59.163	Taeniopygia_guttata
ENSG00000184967	NOC4L	97	55.010	ENSTNIG00000003941	noc4l	99	54.813	Tetraodon_nigroviridis
ENSG00000184967	NOC4L	82	88.608	ENSTTRG00000000638	NOC4L	82	88.608	Tursiops_truncatus
ENSG00000184967	NOC4L	99	84.241	ENSUAMG00000001296	NOC4L	99	84.241	Ursus_americanus
ENSG00000184967	NOC4L	85	84.247	ENSUMAG00000002643	NOC4L	87	84.247	Ursus_maritimus
ENSG00000184967	NOC4L	85	81.507	ENSVVUG00000004449	NOC4L	100	81.176	Vulpes_vulpes
ENSG00000184967	NOC4L	97	58.333	ENSXETG00000002043	noc4l	96	58.333	Xenopus_tropicalis
ENSG00000184967	NOC4L	97	55.888	ENSXCOG00000004716	noc4l	95	55.888	Xiphophorus_couchianus
ENSG00000184967	NOC4L	97	55.888	ENSXMAG00000000964	noc4l	95	55.888	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	19274049.	ISM	Function
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0005515	protein binding	16189514.25416956.	IPI	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0005730	nucleolus	-	ISS	Component
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0006364	rRNA processing	-	ISS	Process
GO:0006364	rRNA processing	-	TAS	Process
GO:0016021	integral component of membrane	-	IEA	Component
GO:0030692	Noc4p-Nop14p complex	21873635.	IBA	Component
GO:0031965	nuclear membrane	-	IEA	Component
GO:0032040	small-subunit processome	21873635.	IBA	Component

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr12	132148836	Missense_Mutation	novel	L281P	0.12
BLCA	chr12	132148103	Silent	rs745832393	L245L	0.24
BRCA	chr12	132150980	Splice_Site	NA	X303_splice	0.33
BRCA	chr12	132147380	Missense_Mutation	novel	L149F	0.1
CESC	chr12	132145624	Missense_Mutation	rs766320330	R102C	0.33
CESC	chr12	132151811	Missense_Mutation	novel	W436C	0.27	CBF
CESC	chr12	132152400	Silent	NA	*517*	0.38
COAD	chr12	132144888	Missense_Mutation	NA	R51H	0.5
COAD	chr12	132151600	Missense_Mutation	NA	R397L	0.37	CBF
COAD	chr12	132147883	Frame_Shift_Del	NA	*A205Pfs13**	0.24
COAD	chr12	132151755	Missense_Mutation	novel	Y418H	0.24	CBF
COAD	chr12	132147710	Silent	rs147903181	Y177Y	0.14
COAD	chr12	132144885	Missense_Mutation	NA	V50A	0.2
COAD	chr12	132147311	Missense_Mutation	rs375092329	V126M	0.37
COAD	chr12	132147296	Missense_Mutation	rs375866510	A121T	0.23
COAD	chr12	132147753	Missense_Mutation	NA	V192M	0.19
COAD	chr12	132145621	Missense_Mutation	NA	N101D	0.23
COAD	chr12	132147883	Frame_Shift_Del	NA	*A205Pfs13**	0.44
COAD	chr12	132145625	Missense_Mutation	rs577947175	R102H	0.54
COAD	chr12	132150980	Splice_Site	NA	X303_splice	0.25
COAD	chr12	132151548	Frame_Shift_Del	NA	*P381Lfs103**	0.35	CBF
COAD	chr12	132151629	Missense_Mutation	rs539569004	R407C	0.32	CBF
COAD	chr12	132147882	Frame_Shift_Ins	novel	*A205Rfs74**	0.45
ESCA	chr12	132152365	Silent	rs74890820	P505P	0.22
ESCA	chr12	132144944	Nonsense_Mutation	novel	Q70*	0.18
ESCA	chr12	132144965	Missense_Mutation	novel	V77I	0.27
ESCA	chr12	132151296	Frame_Shift_Ins	novel	*D335Gfs18**	0.22	CBF
ESCA	chr12	132152361	Missense_Mutation	novel	R504L	0.07
GBM	chr12	132151352	Missense_Mutation	NA	L353F	0.04	CBF
HNSC	chr12	132148864	Missense_Mutation	novel	M290I	0.24
HNSC	chr12	132151580	Silent	novel	F390F	0.6
KIRC	chr12	132151504	Missense_Mutation	NA	V365A	0.3	CBF
LIHC	chr12	132151491	Missense_Mutation	rs554287010	P361S	0.25	CBF
LIHC	chr12	132151505	Silent	rs375514217	V365V	0.47
LUAD	chr12	132151600	Missense_Mutation	NA	R397L	0.29	CBF
LUAD	chr12	132147896	Frame_Shift_Del	novel	W207*	0.17
LUAD	chr12	132145663	Missense_Mutation	NA	K115Q	0.17
LUAD	chr12	132145665	Missense_Mutation	novel	K115N	0.17
LUAD	chr12	132152122	Silent	rs541204285	A452A	0.41
LUAD	chr12	132152123	Missense_Mutation	rs755773641	A453S	0.39	CBF
LUAD	chr12	132147315	Missense_Mutation	novel	Q127L	0.16
LUSC	chr12	132147705	Missense_Mutation	novel	D176N	0.06
LUSC	chr12	132147901	Missense_Mutation	novel	N209Y	0.31
LUSC	chr12	132152195	Missense_Mutation	rs367698251	E477K	0.31
LUSC	chr12	132151369	Splice_Site	novel	X358_splice	0.43
MESO	chr12	132152086	Splice_Region	rs771941255	A440A	0.27
OV	chr12	132147911	Missense_Mutation	rs141988623	T212M	0.31
OV	chr12	132145646	Missense_Mutation	novel	H109R	0.24
PAAD	chr12	132151325	Missense_Mutation	rs758550684	R344C	0.17	CBF
PAAD	chr12	132152128	Silent	rs753389452	S454S	0.15
PAAD	chr12	132152142	Missense_Mutation	novel	A459V	0.14
SARC	chr12	132147715	Missense_Mutation	novel	D179G	0.08
SARC	chr12	132147659	Silent	novel	P160P	0.16
SARC	chr12	132152135	Missense_Mutation	novel	N457D	0.15
SKCM	chr12	132152148	Missense_Mutation	NA	S461F	0.41
SKCM	chr12	132147385	Silent	novel	F150F	0.35
SKCM	chr12	132151558	Missense_Mutation	novel	A383V	0.37	CBF
SKCM	chr12	132151513	Missense_Mutation	novel	F368C	0.21	CBF
SKCM	chr12	132151514	Silent	rs368698447	F368F	0.2
SKCM	chr12	132151760	Silent	rs746625024	D419D	0.44
SKCM	chr12	132152085	Missense_Mutation	novel	A440V	0.71	CBF
SKCM	chr12	132144950	Missense_Mutation	NA	P72S	0.27
STAD	chr12	132147744	Missense_Mutation	rs780906260	V189M	0.08
STAD	chr12	132147776	Frame_Shift_Del	novel	*E201Rfs17**	0.18
STAD	chr12	132151515	Missense_Mutation	rs752337906	A369T	0.36	CBF
STAD	chr12	132147883	Frame_Shift_Del	NA	*A205Pfs13**	0.35
STAD	chr12	132151327	Silent	rs772358688	R344R	0.12
STAD	chr12	132147721	Missense_Mutation	NA	R181H	0.42
STAD	chr12	132147951	Silent	rs755304546	T225T	0.33
STAD	chr12	132147760	Missense_Mutation	novel	R194Q	0.35
STAD	chr12	132150987	Missense_Mutation	novel	A303G	0.35
STAD	chr12	132147925	Missense_Mutation	rs201466638	V217M	0.77
STAD	chr12	132147883	Frame_Shift_Del	NA	*A205Pfs13**	0.15
STAD	chr12	132147883	Frame_Shift_Del	NA	*A205Pfs13**	0.29
UCEC	chr12	132152425	3'UTR	novel		0.29
UCEC	chr12	132150986	Missense_Mutation	novel	A303T	0.13
UCEC	chr12	132152144	Silent	novel	L460L	0.2
UCEC	chr12	132147729	Missense_Mutation	rs764680094	T184A	0.43
UCEC	chr12	132145604	Missense_Mutation	rs756158873	R95H	0.43
UCEC	chr12	132152165	Missense_Mutation	novel	I467V	0.31
UCEC	chr12	132148850	Missense_Mutation	novel	Q286E	1
UCEC	chr12	132147668	Silent	novel	D163D	0.47
UCEC	chr12	132151350	Missense_Mutation	NA	D352G	0.46	CBF
UCEC	chr12	132148103	Silent	rs745832393	L245L	0.17
UCEC	chr12	132147744	Missense_Mutation	rs780906260	V189M	0.25
UCEC	chr12	132151570	Missense_Mutation	novel	V387A	0.32	CBF
UCEC	chr12	132147713	Silent	rs199638081	D178D	0.32
UCEC	chr12	132145653	Silent	novel	S111S	0.49
UCEC	chr12	132152171	Missense_Mutation	novel	P469S	0.47
UCEC	chr12	132147881	Missense_Mutation	novel	V202E	0.27
UCEC	chr12	132152312	Missense_Mutation	novel	P488S	0.39
UCEC	chr12	132152185	Silent	novel	L473L	0.29
UCEC	chr12	132150987	Missense_Mutation	novel	A303G	0.26
UCEC	chr12	132152314	Silent	rs778833158	P488P	0.38
UCEC	chr12	132152129	Missense_Mutation	rs141373941	V455I	0.44
UCEC	chr12	132147701	Silent	novel	Y174Y	0.31
UCEC	chr12	132152168	Missense_Mutation	rs550210073	A468T	0.06
UCEC	chr12	132152170	Silent	rs140697665	A468A	0.37
UCS	chr12	132148840	Silent	rs144597773	P282P	0.56
UVM	chr12	132148852	Missense_Mutation	rs529616528	Q286H	0.29

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	DEL	0.1544	0.22328
BRCA	DEL	0.1602	6.3933e-07
CHOL	DEL	0.2222	0.067545
HNSC	DEL	0.0785	0.22646
LIHC	DEL	0.1243	2.3723e-05
LUAD	DEL	0.1609	0.0059643
LUSC	DEL	0.1198	0.038823
OV	DEL	0.3402	9.8572e-12
PAAD	DEL	0.1739	0.0030251
PRAD	DEL	0.0711	0.024258
SARC	DEL	0.2062	0.2358
SKCM	DEL	0.1853	0.00079981
UCEC	DEL	0.0928	0.00053229
UCS	DEL	0.3393	0.033261

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
STAD	0.021	Kaplan-Meier Survival Analysis
MESO	0.011	Kaplan-Meier Survival Analysis
ACC	0.0013	Kaplan-Meier Survival Analysis
SKCM	0.029	Kaplan-Meier Survival Analysis
PAAD	0.016	Kaplan-Meier Survival Analysis
CESC	0.045	Kaplan-Meier Survival Analysis
LAML	0.016	Kaplan-Meier Survival Analysis
LIHC	0.0044	Kaplan-Meier Survival Analysis
DLBC	0.011	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742