EuRBPDB

Description

RBDs

RBPome

PRI

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000185163 (Gene tree)
Gene ID: 317781
Gene Symbol: DDX51
Alias: N
Full Name: DEAD-box helicase 51
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 7,742 bases
Position: chr12:132,136,594-132,144,335
Accession: 20082
RBP type: canonical RBP
Summary: (DEAD-Box Helicase 51) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and hydrolase activity. An important paralog of this gene is DDX27.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000380495	ResIII	PF04851.15	4.5e-06	1	1
ENSP00000380495	DEAD	PF00270.29	3.6e-40	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Protein-RNA interaction（RNA-Binding Site）

Click here to download all RNA binding sites

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000462829	DDX51-203	2203	-	-	- (aa)	-	-
ENST00000546058	DDX51-206	789	-	-	- (aa)	-	-
ENST00000541489	DDX51-204	806	-	-	- (aa)	-	-
ENST00000545991	DDX51-205	1734	-	-	- (aa)	-	-
ENST00000397333	DDX51-202	4718	XM_011538256	ENSP00000380495	666 (aa)	XP_011536558	Q8N8A6
ENST00000329073	DDX51-201	2341	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000185163's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000185163's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000185163	DDX51	61	30.649	ENSG00000125485	DDX31	53	30.649
ENSG00000185163	DDX51	61	30.000	ENSG00000278053	DDX52	58	30.000
ENSG00000185163	DDX51	60	30.864	ENSG00000105671	DDX49	70	30.864

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000185163	DDX51	56	42.895	ENSAPOG00000013644	ddx51	90	44.767	Acanthochromis_polyacanthus
ENSG00000185163	DDX51	82	79.636	ENSAMEG00000013674	DDX51	99	79.636	Ailuropoda_melanoleuca
ENSG00000185163	DDX51	73	59.796	ENSACIG00000010201	ddx51	76	59.796	Amphilophus_citrinellus
ENSG00000185163	DDX51	99	50.593	ENSAOCG00000017332	ddx51	100	50.445	Amphiprion_ocellaris
ENSG00000185163	DDX51	99	50.146	ENSAPEG00000004829	ddx51	100	50.073	Amphiprion_percula
ENSG00000185163	DDX51	99	50.075	ENSATEG00000013470	ddx51	99	50.749	Anabas_testudineus
ENSG00000185163	DDX51	100	83.784	ENSANAG00000031596	DDX51	100	83.934	Aotus_nancymaae
ENSG00000185163	DDX51	99	50.000	ENSACLG00000020492	ddx51	99	50.075	Astatotilapia_calliptera
ENSG00000185163	DDX51	99	48.063	ENSAMXG00000001507	ddx51	97	48.063	Astyanax_mexicanus
ENSG00000185163	DDX51	100	75.740	ENSBTAG00000017219	DDX51	100	76.036	Bos_taurus
ENSG00000185163	DDX51	67	30.937	WBGene00022792	ZK686.2	72	30.937	Caenorhabditis_elegans
ENSG00000185163	DDX51	100	88.690	ENSCJAG00000046414	DDX51	100	88.244	Callithrix_jacchus
ENSG00000185163	DDX51	100	72.605	ENSCAFG00000006320	DDX51	100	73.503	Canis_familiaris
ENSG00000185163	DDX51	100	68.843	ENSCAFG00020010492	DDX51	100	69.539	Canis_lupus_dingo
ENSG00000185163	DDX51	100	75.186	ENSCHIG00000014268	DDX51	100	75.186	Capra_hircus
ENSG00000185163	DDX51	74	88.641	ENSTSYG00000034346	DDX51	83	88.641	Carlito_syrichta
ENSG00000185163	DDX51	100	78.743	ENSCPOG00000023923	DDX51	100	78.293	Cavia_porcellus
ENSG00000185163	DDX51	100	89.039	ENSCCAG00000031005	DDX51	100	88.589	Cebus_capucinus
ENSG00000185163	DDX51	100	92.793	ENSCATG00000034250	DDX51	100	92.793	Cercocebus_atys
ENSG00000185163	DDX51	100	93.572	ENSCSAG00000001868	DDX51	100	93.572	Chlorocebus_sabaeus
ENSG00000185163	DDX51	81	64.954	ENSCPBG00000001164	DDX51	74	64.954	Chrysemys_picta_bellii
ENSG00000185163	DDX51	75	39.319	ENSCING00000000770	-	100	40.803	Ciona_intestinalis
ENSG00000185163	DDX51	99	37.092	ENSCSAVG00000010817	-	99	37.092	Ciona_savignyi
ENSG00000185163	DDX51	100	92.365	ENSCANG00000032770	DDX51	100	92.216	Colobus_angolensis_palliatus
ENSG00000185163	DDX51	100	77.096	ENSCGRG00001007401	Ddx51	100	76.497	Cricetulus_griseus_chok1gshd
ENSG00000185163	DDX51	87	79.038	ENSCGRG00000005173	Ddx51	100	79.038	Cricetulus_griseus_crigri
ENSG00000185163	DDX51	99	49.621	ENSCSEG00000015970	ddx51	99	50.000	Cynoglossus_semilaevis
ENSG00000185163	DDX51	57	59.712	ENSCVAG00000017562	ddx51	81	59.712	Cyprinodon_variegatus
ENSG00000185163	DDX51	76	58.929	ENSDARG00000025854	ddx51	99	48.980	Danio_rerio
ENSG00000185163	DDX51	74	82.093	ENSDNOG00000014194	DDX51	99	82.093	Dasypus_novemcinctus
ENSG00000185163	DDX51	80	40.175	FBgn0004556	Dbp73D	81	40.175	Drosophila_melanogaster
ENSG00000185163	DDX51	80	48.513	ENSEBUG00000016425	ddx51	95	48.513	Eptatretus_burgeri
ENSG00000185163	DDX51	100	77.381	ENSEASG00005016622	DDX51	100	77.530	Equus_asinus_asinus
ENSG00000185163	DDX51	81	77.555	ENSECAG00000018910	DDX51	63	77.555	Equus_caballus
ENSG00000185163	DDX51	99	48.378	ENSELUG00000018602	ddx51	99	47.953	Esox_lucius
ENSG00000185163	DDX51	100	76.233	ENSFCAG00000010782	DDX51	100	76.751	Felis_catus
ENSG00000185163	DDX51	96	55.407	ENSFALG00000007216	DDX51	97	55.248	Ficedula_albicollis
ENSG00000185163	DDX51	67	84.257	ENSFDAG00000013231	DDX51	87	84.257	Fukomys_damarensis
ENSG00000185163	DDX51	68	60.177	ENSFHEG00000008807	ddx51	74	60.177	Fundulus_heteroclitus
ENSG00000185163	DDX51	75	56.600	ENSGMOG00000012614	ddx51	97	49.216	Gadus_morhua
ENSG00000185163	DDX51	90	60.196	ENSGALG00000032690	DDX51	96	61.111	Gallus_gallus
ENSG00000185163	DDX51	75	55.422	ENSGAFG00000019988	ddx51	93	48.499	Gambusia_affinis
ENSG00000185163	DDX51	99	50.733	ENSGACG00000012252	ddx51	99	51.574	Gasterosteus_aculeatus
ENSG00000185163	DDX51	100	52.503	ENSGAGG00000009833	DDX51	74	64.207	Gopherus_agassizii
ENSG00000185163	DDX51	100	90.841	ENSGGOG00000010250	DDX51	100	90.841	Gorilla_gorilla
ENSG00000185163	DDX51	99	48.416	ENSHBUG00000007532	ddx51	99	48.416	Haplochromis_burtoni
ENSG00000185163	DDX51	100	75.793	ENSHGLG00000009892	DDX51	100	75.000	Heterocephalus_glaber_female
ENSG00000185163	DDX51	99	48.301	ENSHCOG00000016131	ddx51	99	48.154	Hippocampus_comes
ENSG00000185163	DDX51	99	50.224	ENSIPUG00000009240	ddx51	99	50.224	Ictalurus_punctatus
ENSG00000185163	DDX51	81	83.670	ENSSTOG00000023762	DDX51	90	83.670	Ictidomys_tridecemlineatus
ENSG00000185163	DDX51	75	58.600	ENSKMAG00000019797	ddx51	86	52.911	Kryptolebias_marmoratus
ENSG00000185163	DDX51	99	51.118	ENSLBEG00000025627	ddx51	99	50.969	Labrus_bergylta
ENSG00000185163	DDX51	99	49.641	ENSLACG00000011076	DDX51	96	50.681	Latimeria_chalumnae
ENSG00000185163	DDX51	99	48.326	ENSLOCG00000006858	ddx51	99	48.392	Lepisosteus_oculatus
ENSG00000185163	DDX51	90	76.694	ENSLAFG00000008274	DDX51	98	77.403	Loxodonta_africana
ENSG00000185163	DDX51	100	94.144	ENSMFAG00000031189	DDX51	100	94.144	Macaca_fascicularis
ENSG00000185163	DDX51	100	93.994	ENSMNEG00000032293	DDX51	100	93.994	Macaca_nemestrina
ENSG00000185163	DDX51	99	50.368	ENSMAMG00000001462	ddx51	99	50.221	Mastacembelus_armatus
ENSG00000185163	DDX51	99	49.849	ENSMZEG00005012591	ddx51	99	49.925	Maylandia_zebra
ENSG00000185163	DDX51	81	64.140	ENSMGAG00000007549	DDX51	98	62.111	Meleagris_gallopavo
ENSG00000185163	DDX51	100	76.347	ENSMAUG00000012100	Ddx51	100	75.749	Mesocricetus_auratus
ENSG00000185163	DDX51	100	79.880	ENSMICG00000037047	DDX51	100	79.730	Microcebus_murinus
ENSG00000185163	DDX51	78	69.905	ENSMOCG00000011638	-	97	69.754	Microtus_ochrogaster
ENSG00000185163	DDX51	97	66.870	ENSMOCG00000021818	-	91	68.118	Microtus_ochrogaster
ENSG00000185163	DDX51	94	63.391	ENSMODG00000015355	DDX51	98	63.840	Monodelphis_domestica
ENSG00000185163	DDX51	99	50.453	ENSMALG00000013852	ddx51	99	50.526	Monopterus_albus
ENSG00000185163	DDX51	100	75.934	MGP_CAROLIEiJ_G0027549	Ddx51	100	75.187	Mus_caroli
ENSG00000185163	DDX51	100	75.410	ENSMUSG00000029504	Ddx51	100	74.667	Mus_musculus
ENSG00000185163	DDX51	100	73.926	MGP_PahariEiJ_G0024131	Ddx51	100	73.333	Mus_pahari
ENSG00000185163	DDX51	100	75.559	MGP_SPRETEiJ_G0028547	Ddx51	97	93.243	Mus_spretus
ENSG00000185163	DDX51	74	83.773	ENSMPUG00000002384	DDX51	99	83.773	Mustela_putorius_furo
ENSG00000185163	DDX51	74	76.613	ENSMLUG00000029430	DDX51	100	76.613	Myotis_lucifugus
ENSG00000185163	DDX51	99	75.299	ENSNGAG00000020870	Ddx51	99	75.000	Nannospalax_galili
ENSG00000185163	DDX51	99	50.302	ENSNBRG00000013764	ddx51	99	50.755	Neolamprologus_brichardi
ENSG00000185163	DDX51	87	91.595	ENSNLEG00000008548	-	100	91.938	Nomascus_leucogenys
ENSG00000185163	DDX51	73	75.876	ENSMEUG00000004004	DDX51	83	75.876	Notamacropus_eugenii
ENSG00000185163	DDX51	81	82.746	ENSODEG00000009622	DDX51	100	78.902	Octodon_degus
ENSG00000185163	DDX51	99	48.476	ENSONIG00000001627	ddx51	100	48.476	Oreochromis_niloticus
ENSG00000185163	DDX51	96	64.000	ENSOANG00000012187	DDX51	96	64.431	Ornithorhynchus_anatinus
ENSG00000185163	DDX51	74	83.434	ENSOCUG00000024699	DDX51	99	83.434	Oryctolagus_cuniculus
ENSG00000185163	DDX51	99	50.525	ENSORLG00000017814	ddx51	99	50.525	Oryzias_latipes
ENSG00000185163	DDX51	99	50.751	ENSORLG00020016405	ddx51	99	50.751	Oryzias_latipes_hni
ENSG00000185163	DDX51	99	50.375	ENSORLG00015014512	ddx51	99	50.375	Oryzias_latipes_hsok
ENSG00000185163	DDX51	99	51.360	ENSOMEG00000001919	ddx51	99	50.972	Oryzias_melastigma
ENSG00000185163	DDX51	100	80.238	ENSOGAG00000030755	DDX51	100	80.089	Otolemur_garnettii
ENSG00000185163	DDX51	100	76.593	ENSOARG00000011942	DDX51	100	76.296	Ovis_aries
ENSG00000185163	DDX51	96	84.806	ENSPPAG00000028768	DDX51	90	91.237	Pan_paniscus
ENSG00000185163	DDX51	92	72.638	ENSPPRG00000015010	DDX51	94	71.824	Panthera_pardus
ENSG00000185163	DDX51	100	97.147	ENSPTRG00000005647	DDX51	100	96.997	Pan_troglodytes
ENSG00000185163	DDX51	100	93.393	ENSPANG00000008107	DDX51	100	93.393	Papio_anubis
ENSG00000185163	DDX51	99	49.635	ENSPKIG00000022075	ddx51	99	50.504	Paramormyrops_kingsleyae
ENSG00000185163	DDX51	71	67.223	ENSPSIG00000003736	DDX51	94	67.223	Pelodiscus_sinensis
ENSG00000185163	DDX51	57	43.750	ENSPMGG00000018683	ddx51	93	44.385	Periophthalmus_magnuspinnatus
ENSG00000185163	DDX51	95	59.375	ENSPCIG00000005052	DDX51	93	60.635	Phascolarctos_cinereus
ENSG00000185163	DDX51	88	52.048	ENSPFOG00000008508	ddx51	99	47.741	Poecilia_formosa
ENSG00000185163	DDX51	88	51.342	ENSPLAG00000023669	ddx51	96	48.382	Poecilia_latipinna
ENSG00000185163	DDX51	88	52.048	ENSPMEG00000011299	ddx51	99	47.741	Poecilia_mexicana
ENSG00000185163	DDX51	75	57.400	ENSPREG00000015992	ddx51	99	48.576	Poecilia_reticulata
ENSG00000185163	DDX51	100	95.495	ENSPPYG00000005135	DDX51	100	95.345	Pongo_abelii
ENSG00000185163	DDX51	86	75.820	ENSPCAG00000009747	DDX51	87	75.820	Procavia_capensis
ENSG00000185163	DDX51	100	80.389	ENSPCOG00000019597	DDX51	100	80.240	Propithecus_coquereli
ENSG00000185163	DDX51	99	76.024	ENSPVAG00000000454	DDX51	100	76.935	Pteropus_vampyrus
ENSG00000185163	DDX51	99	49.420	ENSPNAG00000017430	ddx51	99	49.637	Pygocentrus_nattereri
ENSG00000185163	DDX51	100	75.262	ENSRNOG00000037480	Ddx51	100	74.813	Rattus_norvegicus
ENSG00000185163	DDX51	100	88.438	ENSRROG00000029937	DDX51	100	88.889	Rhinopithecus_roxellana
ENSG00000185163	DDX51	66	31.770	YNR038W	-	68	31.770	Saccharomyces_cerevisiae
ENSG00000185163	DDX51	83	92.058	ENSSBOG00000018712	DDX51	93	92.058	Saimiri_boliviensis_boliviensis
ENSG00000185163	DDX51	96	63.594	ENSSHAG00000011696	DDX51	94	64.209	Sarcophilus_harrisii
ENSG00000185163	DDX51	99	50.000	ENSSFOG00015002636	ddx51	99	51.938	Scleropages_formosus
ENSG00000185163	DDX51	99	50.737	ENSSMAG00000018065	ddx51	99	50.590	Scophthalmus_maximus
ENSG00000185163	DDX51	83	56.884	ENSSDUG00000001495	ddx51	99	50.295	Seriola_dumerili
ENSG00000185163	DDX51	99	49.926	ENSSLDG00000006541	ddx51	96	50.370	Seriola_lalandi_dorsalis
ENSG00000185163	DDX51	91	58.564	ENSSPUG00000015618	DDX51	89	62.081	Sphenodon_punctatus
ENSG00000185163	DDX51	99	50.657	ENSSPAG00000019759	ddx51	100	50.511	Stegastes_partitus
ENSG00000185163	DDX51	88	77.419	ENSSSCG00000028735	DDX51	100	72.754	Sus_scrofa
ENSG00000185163	DDX51	73	65.644	ENSTGUG00000010243	DDX51	100	65.644	Taeniopygia_guttata
ENSG00000185163	DDX51	99	50.074	ENSTRUG00000012670	ddx51	99	50.149	Takifugu_rubripes
ENSG00000185163	DDX51	99	48.795	ENSTNIG00000010281	ddx51	99	54.209	Tetraodon_nigroviridis
ENSG00000185163	DDX51	66	78.330	ENSTBEG00000006060	DDX51	100	78.330	Tupaia_belangeri
ENSG00000185163	DDX51	100	67.107	ENSTTRG00000000634	DDX51	100	67.257	Tursiops_truncatus
ENSG00000185163	DDX51	80	79.026	ENSUMAG00000002652	DDX51	95	68.874	Ursus_maritimus
ENSG00000185163	DDX51	88	75.885	ENSVVUG00000004382	DDX51	100	76.223	Vulpes_vulpes
ENSG00000185163	DDX51	99	52.226	ENSXETG00000022359	ddx51	99	52.367	Xenopus_tropicalis
ENSG00000185163	DDX51	89	51.759	ENSXCOG00000003043	ddx51	94	50.000	Xiphophorus_couchianus
ENSG00000185163	DDX51	92	51.290	ENSXMAG00000010009	ddx51	100	48.763	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0004386	helicase activity	-	IEA	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005730	nucleolus	-	IEA	Component
GO:0006364	rRNA processing	-	IEA	Process
GO:0016020	membrane	19946888.	HDA	Component