EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000185418 (Gene tree)
Gene ID: 123283
Gene Symbol: TARSL2
Alias: FLJ25005
Full Name: threonyl-tRNA synthetase like 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 71,007 bases
Position: chr15:101,653,598-101,724,604
Accession: 24728
RBP type: canonical RBP
Summary: (Threonyl-TRNA Synthetase Like 2) is a Protein Coding gene. Among its related pathways are tRNA Aminoacylation. Gene Ontology (GO) annotations related to this gene include nucleotide binding. An important paralog of this gene is TARS.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000478827	tRNA_SAD	PF07973.14	1.2e-10	1	1
ENSP00000338093	tRNA_SAD	PF07973.14	1.2e-10	1	1
ENSP00000338093	HGTP_anticodon	PF03129.20	1.5e-17	1	1
ENSP00000478827	HGTP_anticodon	PF03129.20	1.5e-07	1	1
ENSP00000478827	tRNA-synt_2b	PF00587.25	8.3e-36	1	1
ENSP00000338093	tRNA-synt_2b	PF00587.25	9.1e-36	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000335968	TARSL2-201	3610	XM_006720386	ENSP00000338093	802 (aa)	XP_006720449	A2RTX5
ENST00000615656	TARSL2-207	2356	XM_017021912	ENSP00000478827	766 (aa)	XP_016877401	B7ZLP8
ENST00000539112	TARSL2-202	2774	-	ENSP00000439899	766 (aa)	-	B7ZLP8
ENST00000557811	TARSL2-203	360	-	-	- (aa)	-	-
ENST00000558533	TARSL2-204	1916	-	ENSP00000452740	148 (aa)	-	H0YKB9
ENST00000560150	TARSL2-206	335	-	-	- (aa)	-	-
ENST00000559492	TARSL2-205	755	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000185418's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa00970	Aminoacyl-tRNA biosynthesis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000185418's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000185418	TARSL2	99	81.507	ENSG00000113407	TARS	94	74.449
ENSG00000185418	TARSL2	97	57.639	ENSG00000143374	TARS2	96	55.759

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000185418	TARSL2	52	57.957	ENSAPOG00000015706	-	99	57.957	Acanthochromis_polyacanthus
ENSG00000185418	TARSL2	96	95.775	ENSAMEG00000003074	TARSL2	100	87.548	Ailuropoda_melanoleuca
ENSG00000185418	TARSL2	55	64.334	ENSACIG00000007759	-	96	64.334	Amphilophus_citrinellus
ENSG00000185418	TARSL2	53	63.679	ENSAOCG00000012359	-	99	63.679	Amphiprion_ocellaris
ENSG00000185418	TARSL2	52	60.333	ENSAPEG00000007512	-	99	60.333	Amphiprion_percula
ENSG00000185418	TARSL2	99	47.260	ENSATEG00000023568	-	95	53.303	Anabas_testudineus
ENSG00000185418	TARSL2	99	89.041	ENSAPLG00000008485	TARSL2	100	80.028	Anas_platyrhynchos
ENSG00000185418	TARSL2	96	87.324	ENSACAG00000000199	TARSL2	99	61.772	Anolis_carolinensis
ENSG00000185418	TARSL2	97	66.667	ENSACAG00000003076	-	100	61.877	Anolis_carolinensis
ENSG00000185418	TARSL2	96	96.479	ENSANAG00000020687	TARSL2	98	89.873	Aotus_nancymaae
ENSG00000185418	TARSL2	99	48.630	ENSACLG00000020262	-	96	53.550	Astatotilapia_calliptera
ENSG00000185418	TARSL2	97	46.207	ENSAMXG00000012533	-	94	52.861	Astyanax_mexicanus
ENSG00000185418	TARSL2	99	81.187	ENSBTAG00000007651	TARSL2	99	81.061	Bos_taurus
ENSG00000185418	TARSL2	97	98.726	ENSCJAG00000017350	TARSL2	99	93.844	Callithrix_jacchus
ENSG00000185418	TARSL2	96	93.662	ENSCAFG00000010453	TARSL2	99	88.317	Canis_familiaris
ENSG00000185418	TARSL2	96	93.662	ENSCAFG00020020868	TARSL2	99	93.821	Canis_lupus_dingo
ENSG00000185418	TARSL2	97	78.472	ENSCHIG00000015264	TARSL2	97	81.702	Capra_hircus
ENSG00000185418	TARSL2	96	93.662	ENSTSYG00000004538	TARSL2	100	91.750	Carlito_syrichta
ENSG00000185418	TARSL2	97	74.126	ENSCAPG00000004815	TARSL2	94	80.507	Cavia_aperea
ENSG00000185418	TARSL2	96	91.549	ENSCPOG00000008850	TARSL2	100	89.616	Cavia_porcellus
ENSG00000185418	TARSL2	96	98.592	ENSCCAG00000030068	TARSL2	99	94.472	Cebus_capucinus
ENSG00000185418	TARSL2	100	96.867	ENSCATG00000037383	TARSL2	100	96.867	Cercocebus_atys
ENSG00000185418	TARSL2	96	92.254	ENSCLAG00000016873	TARSL2	99	87.089	Chinchilla_lanigera
ENSG00000185418	TARSL2	100	96.020	ENSCSAG00000016828	TARSL2	100	96.020	Chlorocebus_sabaeus
ENSG00000185418	TARSL2	85	85.191	ENSCHOG00000001319	TARSL2	100	85.191	Choloepus_hoffmanni
ENSG00000185418	TARSL2	96	90.141	ENSCPBG00000010792	TARSL2	99	76.991	Chrysemys_picta_bellii
ENSG00000185418	TARSL2	96	98.592	ENSCANG00000035438	TARSL2	100	96.643	Colobus_angolensis_palliatus
ENSG00000185418	TARSL2	96	92.254	ENSCGRG00001020827	Tarsl2	98	85.841	Cricetulus_griseus_chok1gshd
ENSG00000185418	TARSL2	96	92.254	ENSCGRG00000011398	Tarsl2	99	88.467	Cricetulus_griseus_crigri
ENSG00000185418	TARSL2	93	47.101	ENSCSEG00000002562	-	99	63.232	Cynoglossus_semilaevis
ENSG00000185418	TARSL2	53	65.802	ENSCVAG00000009253	-	98	65.802	Cyprinodon_variegatus
ENSG00000185418	TARSL2	52	65.952	ENSDARG00000075385	LO017852.1	99	65.952	Danio_rerio
ENSG00000185418	TARSL2	96	85.915	ENSDNOG00000046161	TARSL2	98	86.176	Dasypus_novemcinctus
ENSG00000185418	TARSL2	96	93.662	ENSDORG00000009653	Tarsl2	100	89.474	Dipodomys_ordii
ENSG00000185418	TARSL2	96	95.775	ENSEASG00005017718	TARSL2	98	91.899	Equus_asinus_asinus
ENSG00000185418	TARSL2	96	95.775	ENSECAG00000024315	TARSL2	98	91.646	Equus_caballus
ENSG00000185418	TARSL2	96	92.254	ENSEEUG00000014117	TARSL2	99	91.340	Erinaceus_europaeus
ENSG00000185418	TARSL2	99	44.521	ENSELUG00000013552	-	94	51.729	Esox_lucius
ENSG00000185418	TARSL2	96	94.366	ENSFCAG00000008836	TARSL2	99	89.460	Felis_catus
ENSG00000185418	TARSL2	99	86.986	ENSFALG00000012444	TARSL2	100	76.933	Ficedula_albicollis
ENSG00000185418	TARSL2	88	93.077	ENSFDAG00000002767	TARSL2	100	85.491	Fukomys_damarensis
ENSG00000185418	TARSL2	54	64.531	ENSFHEG00000021877	-	80	64.531	Fundulus_heteroclitus
ENSG00000185418	TARSL2	93	45.652	ENSGMOG00000006184	-	95	52.608	Gadus_morhua
ENSG00000185418	TARSL2	97	53.472	ENSGALG00000043416	-	96	62.500	Gallus_gallus
ENSG00000185418	TARSL2	96	90.845	ENSGALG00000003985	TARSL2	99	75.665	Gallus_gallus
ENSG00000185418	TARSL2	95	49.286	ENSGAFG00000012691	-	95	54.204	Gambusia_affinis
ENSG00000185418	TARSL2	99	47.945	ENSGACG00000011734	-	95	53.961	Gasterosteus_aculeatus
ENSG00000185418	TARSL2	96	90.141	ENSGAGG00000010775	TARSL2	99	76.441	Gopherus_agassizii
ENSG00000185418	TARSL2	97	99.613	ENSGGOG00000007839	TARSL2	100	99.729	Gorilla_gorilla
ENSG00000185418	TARSL2	99	49.315	ENSHBUG00000003411	-	96	54.273	Haplochromis_burtoni
ENSG00000185418	TARSL2	96	92.254	ENSHGLG00000011618	TARSL2	99	87.595	Heterocephalus_glaber_female
ENSG00000185418	TARSL2	96	92.254	ENSHGLG00100016769	TARSL2	100	90.754	Heterocephalus_glaber_male
ENSG00000185418	TARSL2	99	47.260	ENSHCOG00000014119	-	94	52.232	Hippocampus_comes
ENSG00000185418	TARSL2	52	59.048	ENSIPUG00000000099	-	99	59.048	Ictalurus_punctatus
ENSG00000185418	TARSL2	96	94.366	ENSSTOG00000032725	TARSL2	98	89.241	Ictidomys_tridecemlineatus
ENSG00000185418	TARSL2	99	47.945	ENSKMAG00000001354	-	96	54.074	Kryptolebias_marmoratus
ENSG00000185418	TARSL2	53	60.798	ENSLBEG00000026238	-	99	60.798	Labrus_bergylta
ENSG00000185418	TARSL2	96	95.070	ENSLAFG00000011941	TARSL2	99	92.899	Loxodonta_africana
ENSG00000185418	TARSL2	100	96.475	ENSMFAG00000001902	TARSL2	100	96.475	Macaca_fascicularis
ENSG00000185418	TARSL2	100	96.606	ENSMMUG00000000278	TARSL2	100	96.606	Macaca_mulatta
ENSG00000185418	TARSL2	100	96.606	ENSMNEG00000034952	TARSL2	100	96.606	Macaca_nemestrina
ENSG00000185418	TARSL2	96	98.592	ENSMLEG00000035535	TARSL2	99	97.598	Mandrillus_leucophaeus
ENSG00000185418	TARSL2	99	46.575	ENSMAMG00000015032	-	94	53.453	Mastacembelus_armatus
ENSG00000185418	TARSL2	99	48.630	ENSMZEG00005015989	-	96	53.550	Maylandia_zebra
ENSG00000185418	TARSL2	96	90.845	ENSMGAG00000004951	TARSL2	98	84.530	Meleagris_gallopavo
ENSG00000185418	TARSL2	89	90.685	ENSMAUG00000015756	Tarsl2	98	90.685	Mesocricetus_auratus
ENSG00000185418	TARSL2	99	91.783	ENSMICG00000013039	TARSL2	99	94.315	Microcebus_murinus
ENSG00000185418	TARSL2	96	92.958	ENSMOCG00000014909	Tarsl2	98	84.684	Microtus_ochrogaster
ENSG00000185418	TARSL2	50	66.915	ENSMMOG00000016135	-	92	66.915	Mola_mola
ENSG00000185418	TARSL2	96	90.845	ENSMODG00000011941	TARSL2	99	76.522	Monodelphis_domestica
ENSG00000185418	TARSL2	99	43.836	ENSMALG00000007340	-	93	53.464	Monopterus_albus
ENSG00000185418	TARSL2	96	92.958	MGP_CAROLIEiJ_G0029834	Tarsl2	98	85.570	Mus_caroli
ENSG00000185418	TARSL2	96	92.254	ENSMUSG00000030515	Tarsl2	98	85.570	Mus_musculus
ENSG00000185418	TARSL2	96	92.254	MGP_PahariEiJ_G0013059	Tarsl2	98	84.557	Mus_pahari
ENSG00000185418	TARSL2	96	95.070	ENSMPUG00000011032	TARSL2	99	87.737	Mustela_putorius_furo
ENSG00000185418	TARSL2	96	87.324	ENSMLUG00000012870	-	99	83.544	Myotis_lucifugus
ENSG00000185418	TARSL2	96	89.437	ENSMLUG00000024482	-	99	86.097	Myotis_lucifugus
ENSG00000185418	TARSL2	96	90.141	ENSNGAG00000020451	Tarsl2	98	85.227	Nannospalax_galili
ENSG00000185418	TARSL2	99	49.315	ENSNBRG00000003429	-	96	54.273	Neolamprologus_brichardi
ENSG00000185418	TARSL2	100	96.475	ENSNLEG00000000541	TARSL2	100	96.475	Nomascus_leucogenys
ENSG00000185418	TARSL2	81	79.196	ENSMEUG00000002935	TARSL2	82	79.196	Notamacropus_eugenii
ENSG00000185418	TARSL2	96	86.620	ENSOPRG00000002689	-	78	77.246	Ochotona_princeps
ENSG00000185418	TARSL2	96	91.549	ENSODEG00000014454	TARSL2	98	86.962	Octodon_degus
ENSG00000185418	TARSL2	99	49.315	ENSONIG00000006402	-	98	54.491	Oreochromis_niloticus
ENSG00000185418	TARSL2	96	89.437	ENSOANG00000013263	TARSL2	100	85.481	Ornithorhynchus_anatinus
ENSG00000185418	TARSL2	96	89.437	ENSOCUG00000010740	TARSL2	98	87.037	Oryctolagus_cuniculus
ENSG00000185418	TARSL2	99	45.205	ENSORLG00000010391	-	94	52.030	Oryzias_latipes
ENSG00000185418	TARSL2	99	45.205	ENSORLG00020008928	-	95	52.632	Oryzias_latipes_hni
ENSG00000185418	TARSL2	99	45.205	ENSORLG00015014897	-	95	52.632	Oryzias_latipes_hsok
ENSG00000185418	TARSL2	99	46.575	ENSOMEG00000009022	-	95	53.373	Oryzias_melastigma
ENSG00000185418	TARSL2	96	93.662	ENSOGAG00000014311	TARSL2	99	88.931	Otolemur_garnettii
ENSG00000185418	TARSL2	97	77.778	ENSOARG00000016573	TARSL2	99	81.895	Ovis_aries
ENSG00000185418	TARSL2	99	97.733	ENSPPAG00000040066	TARSL2	100	99.134	Pan_paniscus
ENSG00000185418	TARSL2	96	94.366	ENSPPRG00000017275	TARSL2	99	90.518	Panthera_pardus
ENSG00000185418	TARSL2	96	94.366	ENSPTIG00000015184	TARSL2	88	91.607	Panthera_tigris_altaica
ENSG00000185418	TARSL2	100	99.478	ENSPTRG00000007516	TARSL2	100	99.478	Pan_troglodytes
ENSG00000185418	TARSL2	100	94.595	ENSPANG00000022401	TARSL2	99	94.507	Papio_anubis
ENSG00000185418	TARSL2	99	46.575	ENSPKIG00000010658	-	96	63.942	Paramormyrops_kingsleyae
ENSG00000185418	TARSL2	96	90.141	ENSPSIG00000008419	TARSL2	99	88.103	Pelodiscus_sinensis
ENSG00000185418	TARSL2	53	65.647	ENSPMGG00000007785	-	97	65.647	Periophthalmus_magnuspinnatus
ENSG00000185418	TARSL2	96	90.845	ENSPEMG00000019852	Tarsl2	96	87.413	Peromyscus_maniculatus_bairdii
ENSG00000185418	TARSL2	96	89.437	ENSPCIG00000022481	TARSL2	99	76.273	Phascolarctos_cinereus
ENSG00000185418	TARSL2	95	50.000	ENSPFOG00000013444	-	99	53.789	Poecilia_formosa
ENSG00000185418	TARSL2	95	49.286	ENSPLAG00000018145	-	96	53.800	Poecilia_latipinna
ENSG00000185418	TARSL2	95	50.000	ENSPMEG00000023625	-	96	53.949	Poecilia_mexicana
ENSG00000185418	TARSL2	53	65.023	ENSPREG00000017312	-	99	65.023	Poecilia_reticulata
ENSG00000185418	TARSL2	90	99.172	ENSPPYG00000006830	TARSL2	98	99.172	Pongo_abelii
ENSG00000185418	TARSL2	96	92.958	ENSPCAG00000011132	TARSL2	87	86.134	Procavia_capensis
ENSG00000185418	TARSL2	90	95.635	ENSPCOG00000026095	TARSL2	98	95.635	Propithecus_coquereli
ENSG00000185418	TARSL2	99	71.772	ENSPVAG00000012240	TARSL2	98	71.772	Pteropus_vampyrus
ENSG00000185418	TARSL2	99	49.315	ENSPNYG00000004232	-	96	53.846	Pundamilia_nyererei
ENSG00000185418	TARSL2	97	45.139	ENSPNAG00000002308	-	94	53.083	Pygocentrus_nattereri
ENSG00000185418	TARSL2	96	92.254	ENSRNOG00000024460	Tarsl2	98	81.374	Rattus_norvegicus
ENSG00000185418	TARSL2	100	96.214	ENSRBIG00000035707	TARSL2	100	96.214	Rhinopithecus_bieti
ENSG00000185418	TARSL2	100	95.885	ENSRROG00000029492	TARSL2	99	96.203	Rhinopithecus_roxellana
ENSG00000185418	TARSL2	96	97.887	ENSSBOG00000029807	TARSL2	100	96.552	Saimiri_boliviensis_boliviensis
ENSG00000185418	TARSL2	96	90.141	ENSSHAG00000010266	TARSL2	100	79.338	Sarcophilus_harrisii
ENSG00000185418	TARSL2	97	40.278	ENSSFOG00015022086	tars2	90	62.366	Scleropages_formosus
ENSG00000185418	TARSL2	97	46.528	ENSSMAG00000015682	-	96	53.314	Scophthalmus_maximus
ENSG00000185418	TARSL2	53	65.421	ENSSDUG00000007180	-	99	65.421	Seriola_dumerili
ENSG00000185418	TARSL2	52	66.114	ENSSLDG00000015367	-	99	66.114	Seriola_lalandi_dorsalis
ENSG00000185418	TARSL2	73	76.852	ENSSARG00000010994	-	62	77.982	Sorex_araneus
ENSG00000185418	TARSL2	54	87.760	ENSSPUG00000001523	TARSL2	100	87.760	Sphenodon_punctatus
ENSG00000185418	TARSL2	99	43.151	ENSSPAG00000018887	-	95	50.822	Stegastes_partitus
ENSG00000185418	TARSL2	96	85.915	ENSSSCG00000005781	TARSL2	100	87.874	Sus_scrofa
ENSG00000185418	TARSL2	54	56.019	ENSTGUG00000004602	-	100	56.019	Taeniopygia_guttata
ENSG00000185418	TARSL2	99	86.986	ENSTGUG00000005726	TARSL2	100	81.333	Taeniopygia_guttata
ENSG00000185418	TARSL2	53	65.574	ENSTRUG00000015004	-	99	65.574	Takifugu_rubripes
ENSG00000185418	TARSL2	99	38.926	ENSTNIG00000008060	-	96	50.146	Tetraodon_nigroviridis
ENSG00000185418	TARSL2	71	85.912	ENSTBEG00000001134	-	84	85.912	Tupaia_belangeri
ENSG00000185418	TARSL2	96	84.507	ENSTTRG00000016207	TARSL2	100	87.482	Tursiops_truncatus
ENSG00000185418	TARSL2	96	95.775	ENSUAMG00000025366	-	91	86.207	Ursus_americanus
ENSG00000185418	TARSL2	96	95.775	ENSUMAG00000024371	TARSL2	100	94.316	Ursus_maritimus
ENSG00000185418	TARSL2	96	93.662	ENSVVUG00000014742	TARSL2	99	91.108	Vulpes_vulpes
ENSG00000185418	TARSL2	53	65.808	ENSXCOG00000019508	-	99	65.808	Xiphophorus_couchianus
ENSG00000185418	TARSL2	95	49.286	ENSXMAG00000016382	-	95	54.204	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003674	molecular_function	-	ND	Function
GO:0004829	threonine-tRNA ligase activity	21873635.	IBA	Function
GO:0004829	threonine-tRNA ligase activity	-	ISS	Function
GO:0005515	protein binding	24312579.25416956.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005575	cellular_component	-	ND	Component
GO:0005634	nucleus	-	ISS	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	-	ISS	Component
GO:0006435	threonyl-tRNA aminoacylation	21873635.	IBA	Process
GO:0006435	threonyl-tRNA aminoacylation	-	ISS	Process
GO:0008150	biological_process	-	ND	Process