EuRBPDB

Description

Ensembl ID: ENSG00000187051 (Gene tree)
Gene ID: 91582
Gene Symbol: RPS19BP1
Alias: MGC52010|FLJ21770
Full Name: ribosomal protein S19 binding protein 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 3,763 bases
Position: chr22:39,529,093-39,532,855
Accession: 28749
RBP type: non-canonical RBP
Summary: (Ribosomal Protein S19 Binding Protein 1) is a Protein Coding gene. Diseases associated with RPS19BP1 include Osteopetrosis, Autosomal Recessive 2. Among its related pathways are Cellular response to heat stress and Cellular Senescence (REACTOME). Gene Ontology (GO) annotations related to this gene include enzyme binding.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000491966	RPS19BP1-206	647	-	-	- (aa)	-	-
ENST00000459956	RPS19BP1-203	852	-	-	- (aa)	-	-
ENST00000334678	RPS19BP1-201	927	-	ENSP00000333948	136 (aa)	-	Q86WX3
ENST00000472291	RPS19BP1-204	869	-	-	- (aa)	-	-
ENST00000420879	RPS19BP1-202	861	-	ENSP00000399304	69 (aa)	-	F8WFE7
ENST00000488602	RPS19BP1-205	2801	-	-	- (aa)	-	-

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000187051	Schizophrenia	6E-10	26198764
ENSG00000187051	Schizophrenia	8E-6	22883433

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000187051	RPS19BP1	100	74.126	ENSMUSG00000051518	Rps19bp1	100	74.825	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	17964266.24681097.25416956.	IPI	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	16289379.	ISS	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0005730	nucleolus	16289379.	ISS	Component
GO:0005829	cytosol	-	IDA	Component
GO:0019899	enzyme binding	21873635.	IBA	Function
GO:0019899	enzyme binding	23382074.	IPI	Function