EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000187742 (Gene tree)
Gene ID: 79048
Gene Symbol: SECISBP2
Alias: SBP2
Full Name: SECIS binding protein 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 48,645 bases
Position: chr9:89,318,473-89,367,117
Accession: 30972
RBP type: canonical RBP
Summary: The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element; present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000364959	Ribosomal_L7Ae	PF01248.26	3.4e-21	1	1
ENSP00000436650	Ribosomal_L7Ae	PF01248.26	3.5e-21	1	1
ENSP00000364965	Ribosomal_L7Ae	PF01248.26	4e-21	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
18948268	A novel protein domain induces high affinity selenocysteine insertion sequence binding and elongation factor recruitment.	J Biol Chem	2008 Dec 12	Donovan J	doi: 10.1074/jbc.M806008200
12403468	The SBP2 and 15.5 kD/Snu13p proteins share the same RNA binding domain: identification of SBP2 amino acids important to SECIS RNA binding.	RNA	2002 Oct	Allmang C	-
10464275	Purification, redox sensitivity, and RNA binding properties of SECIS-binding protein 2, a protein involved in selenoprotein biosynthesis.	J Biol Chem	1999 Sep 3	Copeland PR	-
19106619	Known turnover and translation regulatory RNA-binding proteins interact with the 3' UTR of SECIS-binding protein 2.	RNA Biol	2009 Jan-Mar	Bubenik JL	-
17636016	The L7Ae RNA binding motif is a multifunctional domain required for the ribosome-dependent Sec incorporation activity of Sec insertion sequence binding protein 2.	Mol Cell Biol	2007 Sep	Caban K	-
17332014	An improved definition of the RNA-binding specificity of SECIS-binding protein 2, an essential component of the selenocysteine incorporation machinery.	Nucleic Acids Res	2007	Clery A	-
17901054	Altered RNA binding activity underlies abnormal thyroid hormone metabolism linked to a mutation in selenocysteine insertion sequence-binding protein 2.	J Biol Chem	2007 Nov 30	Bubenik JL	-
27956496	The RNA-binding protein Secisbp2 differentially modulates UGA codon reassignment and RNA decay.	Nucleic Acids Res	2017 Apr 20	Fradejas-Villar N	doi: 10.1093/nar/gkw1255.
31225282	-	-	-	-	-
31350336	Ribosome profiling of selenoproteins in vivo reveals consequences of pathogenic Secisbp2 missense mutations.	J Biol Chem	2019 Jul 26	Zhao W	doi: 10.1074/jbc.RA119.009369
12370018	Protein factors mediating selenoprotein synthesis.	Curr Protein Pept Sci	2002 Feb	Lescure A	-
12095701	cDNA cloning, expression pattern and RNA binding analysis of human selenocysteine insertion sequence (SECIS) binding protein 2.	Gene	2002 May 29	Lescure A	-
11680849	The selenocysteine incorporation machinery: interactions between the SECIS RNA and the SECIS-binding protein SBP2.	RNA	2001 Oct	Fletcher JE	-
16416259	Size matters: a view of selenocysteine incorporation from the ribosome.	Cell Mol Life Sci	2006 Jan	Caban K	-
10637234	A novel RNA binding protein, SBP2, is required for the translation of mammalian selenoprotein mRNAs.	EMBO J	2000 Jan 17	Copeland PR	-
16131320	Selenoprotein synthesis: a unique translational mechanism used by a diverse family of proteins.	Thyroid	2005 Aug	Hoffmann PR	-
19744324	Evolutionary history of selenocysteine incorporation from the perspective of SECIS binding proteins.	BMC Evol Biol	2009 Sep 10	Donovan J	doi: 10.1186/1471-2148-9-229.
19467292	SECIS-binding protein 2, a key player in selenoprotein synthesis, is an intrinsically disordered protein.	Biochimie	2009 Aug	Olieric V	doi: 10.1016/j.biochi.2009.05.004
17846120	SBP2 binding affinity is a major determinant in differential selenoprotein mRNA translation and sensitivity to nonsense-mediated decay.	Mol Cell Biol	2007 Nov	Squires JE	-
16962588	Identification and characterization of selenoprotein K: an antioxidant in cardiomyocytes.	FEBS Lett	2006 Oct 2	Lu C	-
24817701	Adjustments, extinction, and remains of selenocysteine incorporation machinery in the nematode lineage.	RNA	2014 Jul	Otero L	doi: 10.1261/rna.043877.113
19223320	A short motif in Drosophila SECIS Binding Protein 2 provides differential binding affinity to SECIS RNA hairpins.	Nucleic Acids Res	2009 Apr	Takeuchi A	doi: 10.1093/nar/gkp078
25692238	Characterization of the UGA-recoding and SECIS-binding activities of SECIS-binding protein 2.	RNA Biol	2014	Bubenik JL	doi: 10.1080/15476286.2014.996472.
16508009	Supramolecular complexes mediate selenocysteine incorporation in vivo.	Mol Cell Biol	2006 Mar	Small-Howard A	-
16155186	Characterization of the SECIS binding protein 2 complex required for the co-translational insertion of selenocysteine in mammals.	Nucleic Acids Res	2005 Sep 9	Kinzy SA	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000498819	SECISBP2-208	854	-	-	- (aa)	-	-
ENST00000375807	SECISBP2-202	3462	XM_017015122	ENSP00000364965	854 (aa)	XP_016870611	Q96T21
ENST00000496597	SECISBP2-207	1195	-	-	- (aa)	-	-
ENST00000470305	SECISBP2-205	5405	-	-	- (aa)	-	-
ENST00000477484	SECISBP2-206	617	-	-	- (aa)	-	-
ENST00000425851	SECISBP2-203	826	-	ENSP00000414288	275 (aa)	-	Q5HYY5
ENST00000534113	SECISBP2-209	3584	XM_011519000	ENSP00000436650	786 (aa)	XP_011517302	Q96T21
ENST00000440898	SECISBP2-204	547	-	ENSP00000411573	60 (aa)	-	Q4V370
ENST00000339901	SECISBP2-201	3320	XM_006717282	ENSP00000364959	781 (aa)	XP_006717345	Q96T21

Gene Model

Click here to download ENSG00000187742's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000187742	Glomerular Filtration Rate	1.9851561E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000187742's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000187742	SECISBP2	57	49.284	ENSAPOG00000005939	secisbp2	60	48.760	Acanthochromis_polyacanthus
ENSG00000187742	SECISBP2	100	72.166	ENSAMEG00000003349	SECISBP2	99	72.973	Ailuropoda_melanoleuca
ENSG00000187742	SECISBP2	54	49.065	ENSACIG00000024185	secisbp2	65	58.480	Amphilophus_citrinellus
ENSG00000187742	SECISBP2	57	49.299	ENSAOCG00000019052	secisbp2	61	48.795	Amphiprion_ocellaris
ENSG00000187742	SECISBP2	57	48.297	ENSAPEG00000012971	secisbp2	61	47.791	Amphiprion_percula
ENSG00000187742	SECISBP2	57	49.296	ENSATEG00000001095	secisbp2	62	48.805	Anabas_testudineus
ENSG00000187742	SECISBP2	99	43.017	ENSAPLG00000013053	SECISBP2	100	42.710	Anas_platyrhynchos
ENSG00000187742	SECISBP2	92	43.793	ENSACAG00000016594	SECISBP2	94	43.908	Anolis_carolinensis
ENSG00000187742	SECISBP2	100	92.632	ENSANAG00000028208	SECISBP2	100	92.632	Aotus_nancymaae
ENSG00000187742	SECISBP2	58	49.495	ENSACLG00000019976	secisbp2	62	48.988	Astatotilapia_calliptera
ENSG00000187742	SECISBP2	57	49.190	ENSAMXG00000015953	secisbp2	62	48.185	Astyanax_mexicanus
ENSG00000187742	SECISBP2	100	76.539	ENSBTAG00000001939	SECISBP2	100	80.000	Bos_taurus
ENSG00000187742	SECISBP2	100	93.333	ENSCJAG00000007806	SECISBP2	100	93.333	Callithrix_jacchus
ENSG00000187742	SECISBP2	100	76.682	ENSCAFG00000002188	SECISBP2	100	76.682	Canis_familiaris
ENSG00000187742	SECISBP2	100	76.419	ENSCAFG00020007224	SECISBP2	99	76.706	Canis_lupus_dingo
ENSG00000187742	SECISBP2	100	76.190	ENSCHIG00000010657	SECISBP2	99	76.190	Capra_hircus
ENSG00000187742	SECISBP2	100	77.863	ENSTSYG00000014119	SECISBP2	100	78.626	Carlito_syrichta
ENSG00000187742	SECISBP2	90	78.364	ENSCAPG00000008522	SECISBP2	99	78.075	Cavia_aperea
ENSG00000187742	SECISBP2	100	75.029	ENSCPOG00000014270	SECISBP2	100	75.029	Cavia_porcellus
ENSG00000187742	SECISBP2	100	92.982	ENSCCAG00000013350	SECISBP2	100	92.982	Cebus_capucinus
ENSG00000187742	SECISBP2	100	96.028	ENSCATG00000008304	SECISBP2	100	96.028	Cercocebus_atys
ENSG00000187742	SECISBP2	100	76.690	ENSCLAG00000001166	SECISBP2	96	76.690	Chinchilla_lanigera
ENSG00000187742	SECISBP2	100	96.028	ENSCSAG00000007310	SECISBP2	100	96.028	Chlorocebus_sabaeus
ENSG00000187742	SECISBP2	92	78.788	ENSCHOG00000011084	SECISBP2	83	78.788	Choloepus_hoffmanni
ENSG00000187742	SECISBP2	58	55.010	ENSCPBG00000005608	SECISBP2	99	55.206	Chrysemys_picta_bellii
ENSG00000187742	SECISBP2	100	95.305	ENSCANG00000034551	SECISBP2	100	95.305	Colobus_angolensis_palliatus
ENSG00000187742	SECISBP2	100	70.047	ENSCGRG00001013930	Secisbp2	100	70.047	Cricetulus_griseus_chok1gshd
ENSG00000187742	SECISBP2	100	70.047	ENSCGRG00000002600	Secisbp2	100	70.047	Cricetulus_griseus_crigri
ENSG00000187742	SECISBP2	56	52.212	ENSCVAG00000015876	secisbp2	58	51.663	Cyprinodon_variegatus
ENSG00000187742	SECISBP2	59	48.665	ENSDARG00000073892	secisbp2	85	48.041	Danio_rerio
ENSG00000187742	SECISBP2	100	79.535	ENSDNOG00000009432	SECISBP2	100	79.535	Dasypus_novemcinctus
ENSG00000187742	SECISBP2	100	77.209	ENSDORG00000023182	Secisbp2	100	77.209	Dipodomys_ordii
ENSG00000187742	SECISBP2	92	78.788	ENSETEG00000001262	SECISBP2	92	78.788	Echinops_telfairi
ENSG00000187742	SECISBP2	100	76.779	ENSEASG00005013960	SECISBP2	100	76.779	Equus_asinus_asinus
ENSG00000187742	SECISBP2	100	77.130	ENSECAG00000015868	SECISBP2	100	77.130	Equus_caballus
ENSG00000187742	SECISBP2	100	70.698	ENSEEUG00000004400	SECISBP2	100	70.664	Erinaceus_europaeus
ENSG00000187742	SECISBP2	100	71.212	ENSFCAG00000004214	SECISBP2	100	72.028	Felis_catus
ENSG00000187742	SECISBP2	99	42.794	ENSFALG00000012441	SECISBP2	94	42.731	Ficedula_albicollis
ENSG00000187742	SECISBP2	100	76.650	ENSFDAG00000021183	SECISBP2	96	76.546	Fukomys_damarensis
ENSG00000187742	SECISBP2	57	47.262	ENSFHEG00000004095	secisbp2	62	46.748	Fundulus_heteroclitus
ENSG00000187742	SECISBP2	99	43.696	ENSGALG00000010694	SECISBP2	96	43.370	Gallus_gallus
ENSG00000187742	SECISBP2	56	49.138	ENSGAFG00000016947	secisbp2	60	48.596	Gambusia_affinis
ENSG00000187742	SECISBP2	57	51.183	ENSGACG00000013757	secisbp2	75	50.862	Gasterosteus_aculeatus
ENSG00000187742	SECISBP2	100	98.830	ENSGGOG00000000453	SECISBP2	100	98.830	Gorilla_gorilla
ENSG00000187742	SECISBP2	51	54.321	ENSHBUG00000007014	secisbp2	96	53.563	Haplochromis_burtoni
ENSG00000187742	SECISBP2	100	78.530	ENSHGLG00000014380	SECISBP2	96	78.530	Heterocephalus_glaber_female
ENSG00000187742	SECISBP2	100	78.646	ENSHGLG00100006953	SECISBP2	96	78.646	Heterocephalus_glaber_male
ENSG00000187742	SECISBP2	50	52.488	ENSHCOG00000008010	secisbp2	56	52.488	Hippocampus_comes
ENSG00000187742	SECISBP2	58	49.398	ENSIPUG00000015393	secisbp2	62	48.692	Ictalurus_punctatus
ENSG00000187742	SECISBP2	100	80.326	ENSSTOG00000000921	SECISBP2	100	80.326	Ictidomys_tridecemlineatus
ENSG00000187742	SECISBP2	100	71.842	ENSJJAG00000020492	Secisbp2	100	71.842	Jaculus_jaculus
ENSG00000187742	SECISBP2	57	49.293	ENSKMAG00000007129	secisbp2	64	49.190	Kryptolebias_marmoratus
ENSG00000187742	SECISBP2	83	41.690	ENSLBEG00000026023	secisbp2	82	41.890	Labrus_bergylta
ENSG00000187742	SECISBP2	56	55.106	ENSLACG00000005735	SECISBP2	87	54.641	Latimeria_chalumnae
ENSG00000187742	SECISBP2	57	49.896	ENSLOCG00000011742	secisbp2	80	49.792	Lepisosteus_oculatus
ENSG00000187742	SECISBP2	100	72.769	ENSLAFG00000012998	SECISBP2	100	72.769	Loxodonta_africana
ENSG00000187742	SECISBP2	100	96.262	ENSMFAG00000003045	SECISBP2	100	96.262	Macaca_fascicularis
ENSG00000187742	SECISBP2	100	96.262	ENSMMUG00000012532	SECISBP2	100	96.262	Macaca_mulatta
ENSG00000187742	SECISBP2	100	96.028	ENSMNEG00000031737	SECISBP2	100	96.028	Macaca_nemestrina
ENSG00000187742	SECISBP2	100	95.685	ENSMLEG00000028868	SECISBP2	100	95.685	Mandrillus_leucophaeus
ENSG00000187742	SECISBP2	56	47.639	ENSMAMG00000006644	secisbp2	78	39.403	Mastacembelus_armatus
ENSG00000187742	SECISBP2	58	49.495	ENSMZEG00005013614	secisbp2	62	48.988	Maylandia_zebra
ENSG00000187742	SECISBP2	100	69.231	ENSMAUG00000008659	Secisbp2	100	69.231	Mesocricetus_auratus
ENSG00000187742	SECISBP2	100	86.114	ENSMICG00000001176	SECISBP2	100	86.114	Microcebus_murinus
ENSG00000187742	SECISBP2	100	71.445	ENSMOCG00000000616	Secisbp2	100	71.445	Microtus_ochrogaster
ENSG00000187742	SECISBP2	100	56.326	ENSMODG00000013365	SECISBP2	100	57.317	Monodelphis_domestica
ENSG00000187742	SECISBP2	58	48.323	ENSMALG00000004907	secisbp2	86	40.028	Monopterus_albus
ENSG00000187742	SECISBP2	100	71.312	MGP_CAROLIEiJ_G0018518	Secisbp2	100	71.312	Mus_caroli
ENSG00000187742	SECISBP2	100	71.926	ENSMUSG00000035139	Secisbp2	100	71.926	Mus_musculus
ENSG00000187742	SECISBP2	100	71.013	MGP_PahariEiJ_G0019584	Secisbp2	100	71.013	Mus_pahari
ENSG00000187742	SECISBP2	100	71.857	MGP_SPRETEiJ_G0019399	Secisbp2	100	71.857	Mus_spretus
ENSG00000187742	SECISBP2	71	74.194	ENSMPUG00000008495	-	100	74.194	Mustela_putorius_furo
ENSG00000187742	SECISBP2	100	74.340	ENSMLUG00000012348	SECISBP2	100	74.246	Myotis_lucifugus
ENSG00000187742	SECISBP2	100	73.310	ENSNGAG00000002364	Secisbp2	100	73.310	Nannospalax_galili
ENSG00000187742	SECISBP2	58	50.305	ENSNBRG00000022804	secisbp2	62	49.593	Neolamprologus_brichardi
ENSG00000187742	SECISBP2	100	97.205	ENSNLEG00000008739	SECISBP2	100	97.205	Nomascus_leucogenys
ENSG00000187742	SECISBP2	53	58.824	ENSMEUG00000003854	-	59	58.824	Notamacropus_eugenii
ENSG00000187742	SECISBP2	96	66.048	ENSOPRG00000007588	SECISBP2	99	65.371	Ochotona_princeps
ENSG00000187742	SECISBP2	100	74.883	ENSODEG00000000675	SECISBP2	100	74.883	Octodon_degus
ENSG00000187742	SECISBP2	58	52.838	ENSONIG00000016931	secisbp2	99	54.156	Oreochromis_niloticus
ENSG00000187742	SECISBP2	100	78.200	ENSOCUG00000012932	SECISBP2	100	78.322	Oryctolagus_cuniculus
ENSG00000187742	SECISBP2	57	49.372	ENSORLG00000000343	secisbp2	72	48.847	Oryzias_latipes
ENSG00000187742	SECISBP2	57	48.632	ENSORLG00020012878	secisbp2	70	48.101	Oryzias_latipes_hni
ENSG00000187742	SECISBP2	57	49.791	ENSORLG00015004559	secisbp2	63	49.686	Oryzias_latipes_hsok
ENSG00000187742	SECISBP2	57	49.673	ENSOMEG00000008595	secisbp2	63	49.345	Oryzias_melastigma
ENSG00000187742	SECISBP2	100	84.364	ENSOGAG00000000317	SECISBP2	97	84.364	Otolemur_garnettii
ENSG00000187742	SECISBP2	100	76.009	ENSOARG00000007741	SECISBP2	100	76.009	Ovis_aries
ENSG00000187742	SECISBP2	100	99.181	ENSPPAG00000012385	SECISBP2	100	99.181	Pan_paniscus
ENSG00000187742	SECISBP2	100	71.445	ENSPPRG00000023911	SECISBP2	100	72.261	Panthera_pardus
ENSG00000187742	SECISBP2	100	64.304	ENSPTIG00000009781	SECISBP2	100	65.248	Panthera_tigris_altaica
ENSG00000187742	SECISBP2	100	99.064	ENSPTRG00000021094	SECISBP2	100	99.064	Pan_troglodytes
ENSG00000187742	SECISBP2	100	95.911	ENSPANG00000024873	SECISBP2	100	95.911	Papio_anubis
ENSG00000187742	SECISBP2	96	45.400	ENSPSIG00000016257	SECISBP2	99	46.537	Pelodiscus_sinensis
ENSG00000187742	SECISBP2	100	73.543	ENSPEMG00000020212	Secisbp2	100	73.543	Peromyscus_maniculatus_bairdii
ENSG00000187742	SECISBP2	100	58.333	ENSPCIG00000010304	SECISBP2	100	58.111	Phascolarctos_cinereus
ENSG00000187742	SECISBP2	59	50.106	ENSPFOG00000008146	secisbp2	75	49.364	Poecilia_formosa
ENSG00000187742	SECISBP2	53	53.191	ENSPLAG00000004505	secisbp2	94	52.370	Poecilia_latipinna
ENSG00000187742	SECISBP2	59	47.390	ENSPMEG00000013702	secisbp2	63	46.881	Poecilia_mexicana
ENSG00000187742	SECISBP2	57	48.428	ENSPREG00000008117	secisbp2	62	47.899	Poecilia_reticulata
ENSG00000187742	SECISBP2	100	98.012	ENSPPYG00000019359	SECISBP2	100	98.012	Pongo_abelii
ENSG00000187742	SECISBP2	100	62.126	ENSPCAG00000000559	-	80	66.617	Procavia_capensis
ENSG00000187742	SECISBP2	100	85.181	ENSPCOG00000013354	SECISBP2	100	85.181	Propithecus_coquereli
ENSG00000187742	SECISBP2	93	77.528	ENSPVAG00000011013	SECISBP2	90	77.528	Pteropus_vampyrus
ENSG00000187742	SECISBP2	58	49.495	ENSPNYG00000016799	secisbp2	62	48.988	Pundamilia_nyererei
ENSG00000187742	SECISBP2	56	49.692	ENSPNAG00000029922	secisbp2	65	48.967	Pygocentrus_nattereri
ENSG00000187742	SECISBP2	100	71.911	ENSRNOG00000013773	Secisbp2	100	71.911	Rattus_norvegicus
ENSG00000187742	SECISBP2	100	95.105	ENSRBIG00000044115	SECISBP2	100	95.105	Rhinopithecus_bieti
ENSG00000187742	SECISBP2	100	95.338	ENSRROG00000030742	SECISBP2	100	95.338	Rhinopithecus_roxellana
ENSG00000187742	SECISBP2	80	94.106	ENSSBOG00000015392	SECISBP2	91	94.106	Saimiri_boliviensis_boliviensis
ENSG00000187742	SECISBP2	100	60.620	ENSSHAG00000005947	SECISBP2	100	60.964	Sarcophilus_harrisii
ENSG00000187742	SECISBP2	53	52.347	ENSSFOG00015010409	secisbp2	59	46.484	Scleropages_formosus
ENSG00000187742	SECISBP2	58	49.609	ENSSMAG00000008472	secisbp2	76	49.119	Scophthalmus_maximus
ENSG00000187742	SECISBP2	82	40.831	ENSSDUG00000002089	secisbp2	83	40.177	Seriola_dumerili
ENSG00000187742	SECISBP2	83	40.420	ENSSLDG00000003510	secisbp2	83	40.056	Seriola_lalandi_dorsalis
ENSG00000187742	SECISBP2	97	49.511	ENSSARG00000012518	-	82	59.366	Sorex_araneus
ENSG00000187742	SECISBP2	96	43.025	ENSSPUG00000009635	SECISBP2	98	41.838	Sphenodon_punctatus
ENSG00000187742	SECISBP2	57	50.000	ENSSPAG00000013606	secisbp2	61	49.493	Stegastes_partitus
ENSG00000187742	SECISBP2	100	78.294	ENSSSCG00000028033	SECISBP2	100	78.291	Sus_scrofa
ENSG00000187742	SECISBP2	68	54.212	ENSTGUG00000000440	SECISBP2	99	53.663	Taeniopygia_guttata
ENSG00000187742	SECISBP2	55	48.837	ENSTRUG00000016835	secisbp2	65	48.305	Takifugu_rubripes
ENSG00000187742	SECISBP2	59	50.529	ENSTNIG00000015576	secisbp2	95	51.974	Tetraodon_nigroviridis
ENSG00000187742	SECISBP2	83	80.435	ENSTBEG00000000288	SECISBP2	84	80.435	Tupaia_belangeri
ENSG00000187742	SECISBP2	100	77.156	ENSTTRG00000003339	SECISBP2	98	77.156	Tursiops_truncatus
ENSG00000187742	SECISBP2	100	74.242	ENSUAMG00000016243	SECISBP2	100	74.242	Ursus_americanus
ENSG00000187742	SECISBP2	100	72.405	ENSUMAG00000016261	SECISBP2	100	72.643	Ursus_maritimus
ENSG00000187742	SECISBP2	100	73.232	ENSVVUG00000022278	SECISBP2	99	73.765	Vulpes_vulpes
ENSG00000187742	SECISBP2	60	53.402	ENSXETG00000029955	SECISBP2	86	53.750	Xenopus_tropicalis
ENSG00000187742	SECISBP2	59	48.479	ENSXMAG00000003090	secisbp2	62	47.967	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001514	selenocysteine incorporation	21873635.	IBA	Process
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0003730	mRNA 3'-UTR binding	21873635.	IBA	Function
GO:0003730	mRNA 3'-UTR binding	16962588.17332014.	IDA	Function
GO:0005515	protein binding	25416956.	IPI	Function
GO:0005634	nucleus	-	IEA	Component
GO:0005739	mitochondrion	-	IEA	Component
GO:0021756	striatum development	-	IEA	Process
GO:0035368	selenocysteine insertion sequence binding	21873635.	IBA	Function
GO:0043021	ribonucleoprotein complex binding	21873635.	IBA	Function
GO:0048666	neuron development	-	IEA	Process
GO:1990904	ribonucleoprotein complex	21873635.	IBA	Component
GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	-	IEA	Process