EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000188042 (Gene tree)
Gene ID: 10123
Gene Symbol: ARL4C
Alias: LAK|ARL7
Full Name: ADP ribosylation factor like GTPase 4C
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 4,013 bases
Position: chr2:234,493,041-234,497,053
Accession: 698
RBP type: canonical RBP
Summary: ADP-ribosylation factor-like 4C is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4C is closely similar to ARL4A and ARL4D and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. This protein may play a role in cholesterol transport. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000375057	MMR_HSR1	PF01926.23	4.8e-07	1	1
ENSP00000339754	MMR_HSR1	PF01926.23	5.2e-07	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000390645	ARL4C-202	4013	-	ENSP00000375057	192 (aa)	-	P56559
ENST00000339728	ARL4C-201	3385	-	ENSP00000339754	201 (aa)	-	P56559

Gene Model

Click here to download ENSG00000188042's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000188042	Pancreatic Neoplasms	8.691E-05	22523087
ENSG00000188042	Blood Glucose	7.6680000E-005	-
ENSG00000188042	Blood Glucose	8.1160000E-005	-
ENSG00000188042	Eosinophils	2.3900000E-005	-
ENSG00000188042	Eosinophils	2.3300000E-006	-
ENSG00000188042	Eosinophils	4.9540000E-007	-
ENSG00000188042	Body Mass Index	7.3207014E-006	-
ENSG00000188042	Platelet Function Tests	8.5600000E-006	-
ENSG00000188042	Platelet Function Tests	3.7800000E-006	-
ENSG00000188042	Platelet Function Tests	6.3800000E-006	-
ENSG00000188042	Platelet Function Tests	1.7566100E-005	-
ENSG00000188042	Child Development Disorders, Pervasive	2.9785900E-005	-
ENSG00000188042	gamma-Tocopherol	6.9220000E-005	-
ENSG00000188042	Stomach Neoplasms	3E-7	26701879
ENSG00000188042	Pancreatic Carcinoma	6E-6	20686608
ENSG00000188042	candesartan	8E-6	22566498
ENSG00000188042	Hypertension	8E-6	22566498

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000188042's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000188042	ARL4C	100	95.312	ENSAPOG00000023273	arl4cb	100	95.312	Acanthochromis_polyacanthus
ENSG00000188042	ARL4C	100	100.000	ENSAMEG00000016052	ARL4C	80	100.000	Ailuropoda_melanoleuca
ENSG00000188042	ARL4C	100	95.833	ENSACIG00000000312	arl4cb	100	95.833	Amphilophus_citrinellus
ENSG00000188042	ARL4C	91	83.523	ENSACIG00000024420	-	96	84.043	Amphilophus_citrinellus
ENSG00000188042	ARL4C	100	95.312	ENSAPEG00000019862	arl4cb	100	95.312	Amphiprion_percula
ENSG00000188042	ARL4C	100	96.354	ENSATEG00000019469	arl4cb	100	96.354	Anabas_testudineus
ENSG00000188042	ARL4C	100	83.938	ENSATEG00000013007	-	99	83.938	Anabas_testudineus
ENSG00000188042	ARL4C	100	95.833	ENSAPLG00000015708	ARL4C	100	95.833	Anas_platyrhynchos
ENSG00000188042	ARL4C	100	97.917	ENSACAG00000010087	ARL4C	100	97.917	Anolis_carolinensis
ENSG00000188042	ARL4C	100	100.000	ENSANAG00000038361	ARL4C	99	99.500	Aotus_nancymaae
ENSG00000188042	ARL4C	94	83.425	ENSACLG00000014159	-	99	83.938	Astatotilapia_calliptera
ENSG00000188042	ARL4C	100	95.312	ENSACLG00000014218	arl4cb	100	95.312	Astatotilapia_calliptera
ENSG00000188042	ARL4C	100	93.750	ENSAMXG00000024926	arl4cb	100	93.750	Astyanax_mexicanus
ENSG00000188042	ARL4C	100	69.948	ENSAMXG00000024897	-	100	69.948	Astyanax_mexicanus
ENSG00000188042	ARL4C	100	100.000	ENSCJAG00000042179	ARL4C	99	100.000	Callithrix_jacchus
ENSG00000188042	ARL4C	93	100.000	ENSCAFG00000012001	ARL4C	99	100.000	Canis_familiaris
ENSG00000188042	ARL4C	100	100.000	ENSCAFG00020024408	ARL4C	100	100.000	Canis_lupus_dingo
ENSG00000188042	ARL4C	100	100.000	ENSCHIG00000008457	ARL4C	100	100.000	Capra_hircus
ENSG00000188042	ARL4C	100	100.000	ENSTSYG00000033922	ARL4C	99	99.000	Carlito_syrichta
ENSG00000188042	ARL4C	100	100.000	ENSCCAG00000024558	ARL4C	99	100.000	Cebus_capucinus
ENSG00000188042	ARL4C	100	100.000	ENSCATG00000041801	ARL4C	99	100.000	Cercocebus_atys
ENSG00000188042	ARL4C	100	100.000	ENSCLAG00000010525	ARL4C	99	100.000	Chinchilla_lanigera
ENSG00000188042	ARL4C	100	100.000	ENSCSAG00000018795	ARL4C	100	100.000	Chlorocebus_sabaeus
ENSG00000188042	ARL4C	100	97.396	ENSCPBG00000024707	ARL4C	100	97.396	Chrysemys_picta_bellii
ENSG00000188042	ARL4C	100	100.000	ENSCANG00000035065	ARL4C	99	100.000	Colobus_angolensis_palliatus
ENSG00000188042	ARL4C	100	100.000	ENSCGRG00001010866	Arl4c	100	100.000	Cricetulus_griseus_chok1gshd
ENSG00000188042	ARL4C	100	100.000	ENSCGRG00000018449	Arl4c	100	100.000	Cricetulus_griseus_crigri
ENSG00000188042	ARL4C	100	92.188	ENSCSEG00000000838	arl4cb	89	92.188	Cynoglossus_semilaevis
ENSG00000188042	ARL4C	97	82.353	ENSCSEG00000005387	-	98	82.353	Cynoglossus_semilaevis
ENSG00000188042	ARL4C	99	94.764	ENSCVAG00000020902	arl4cb	99	94.764	Cyprinodon_variegatus
ENSG00000188042	ARL4C	100	80.829	ENSCVAG00000023139	-	99	80.829	Cyprinodon_variegatus
ENSG00000188042	ARL4C	100	95.312	ENSDARG00000032708	arl4cb	100	95.312	Danio_rerio
ENSG00000188042	ARL4C	100	94.792	ENSDARG00000057606	arl4ca	100	94.792	Danio_rerio
ENSG00000188042	ARL4C	100	100.000	ENSDNOG00000045362	ARL4C	100	100.000	Dasypus_novemcinctus
ENSG00000188042	ARL4C	100	100.000	ENSDORG00000028955	Arl4c	100	100.000	Dipodomys_ordii
ENSG00000188042	ARL4C	79	64.474	ENSEBUG00000004741	arl4cb	74	64.474	Eptatretus_burgeri
ENSG00000188042	ARL4C	100	100.000	ENSEASG00005019989	ARL4C	100	100.000	Equus_asinus_asinus
ENSG00000188042	ARL4C	99	99.474	ENSEEUG00000012728	ARL4C	100	99.474	Erinaceus_europaeus
ENSG00000188042	ARL4C	100	95.312	ENSELUG00000004400	arl4cb	100	95.312	Esox_lucius
ENSG00000188042	ARL4C	96	96.739	ENSELUG00000015699	arl4ca	97	96.739	Esox_lucius
ENSG00000188042	ARL4C	100	100.000	ENSFCAG00000033226	ARL4C	99	98.492	Felis_catus
ENSG00000188042	ARL4C	100	97.917	ENSFALG00000015098	ARL4C	100	97.917	Ficedula_albicollis
ENSG00000188042	ARL4C	100	100.000	ENSFDAG00000000777	ARL4C	100	100.000	Fukomys_damarensis
ENSG00000188042	ARL4C	100	94.792	ENSFHEG00000009894	arl4cb	97	94.792	Fundulus_heteroclitus
ENSG00000188042	ARL4C	100	79.275	ENSFHEG00000013017	-	99	79.275	Fundulus_heteroclitus
ENSG00000188042	ARL4C	100	96.354	ENSGMOG00000020467	arl4cb	100	96.354	Gadus_morhua
ENSG00000188042	ARL4C	91	97.714	ENSGALG00000052743	ARL4C	100	97.714	Gallus_gallus
ENSG00000188042	ARL4C	100	95.312	ENSGAFG00000020556	arl4cb	99	95.312	Gambusia_affinis
ENSG00000188042	ARL4C	100	95.833	ENSGACG00000008143	arl4cb	100	95.833	Gasterosteus_aculeatus
ENSG00000188042	ARL4C	100	96.875	ENSGAGG00000013550	ARL4C	100	96.875	Gopherus_agassizii
ENSG00000188042	ARL4C	100	100.000	ENSGGOG00000023462	ARL4C	100	100.000	Gorilla_gorilla
ENSG00000188042	ARL4C	100	95.312	ENSHBUG00000002490	arl4cb	100	95.312	Haplochromis_burtoni
ENSG00000188042	ARL4C	94	83.425	ENSHBUG00000009561	-	99	83.938	Haplochromis_burtoni
ENSG00000188042	ARL4C	100	100.000	ENSHGLG00000020294	ARL4C	100	100.000	Heterocephalus_glaber_female
ENSG00000188042	ARL4C	97	82.447	ENSHCOG00000008233	arl4cb	94	82.447	Hippocampus_comes
ENSG00000188042	ARL4C	100	78.646	ENSIPUG00000006298	-	100	78.646	Ictalurus_punctatus
ENSG00000188042	ARL4C	100	93.750	ENSIPUG00000002122	arl4cb	100	93.750	Ictalurus_punctatus
ENSG00000188042	ARL4C	100	100.000	ENSSTOG00000023217	ARL4C	100	100.000	Ictidomys_tridecemlineatus
ENSG00000188042	ARL4C	100	99.479	ENSJJAG00000010006	Arl4c	100	99.479	Jaculus_jaculus
ENSG00000188042	ARL4C	100	95.312	ENSKMAG00000011334	arl4cb	100	95.312	Kryptolebias_marmoratus
ENSG00000188042	ARL4C	100	95.833	ENSLBEG00000012677	arl4cb	100	95.833	Labrus_bergylta
ENSG00000188042	ARL4C	100	83.420	ENSLBEG00000010335	-	99	83.420	Labrus_bergylta
ENSG00000188042	ARL4C	100	94.271	ENSLACG00000015350	ARL4C	99	93.434	Latimeria_chalumnae
ENSG00000188042	ARL4C	100	96.354	ENSLOCG00000017842	arl4cb	98	96.354	Lepisosteus_oculatus
ENSG00000188042	ARL4C	100	100.000	ENSLAFG00000028097	ARL4C	100	100.000	Loxodonta_africana
ENSG00000188042	ARL4C	100	100.000	ENSMFAG00000045232	ARL4C	99	100.000	Macaca_fascicularis
ENSG00000188042	ARL4C	100	100.000	ENSMMUG00000011516	ARL4C	100	100.000	Macaca_mulatta
ENSG00000188042	ARL4C	100	100.000	ENSMNEG00000031224	ARL4C	99	100.000	Macaca_nemestrina
ENSG00000188042	ARL4C	100	100.000	ENSMLEG00000027620	ARL4C	99	100.000	Mandrillus_leucophaeus
ENSG00000188042	ARL4C	100	95.833	ENSMAMG00000013367	arl4cb	100	95.833	Mastacembelus_armatus
ENSG00000188042	ARL4C	100	84.456	ENSMAMG00000022482	-	97	84.456	Mastacembelus_armatus
ENSG00000188042	ARL4C	100	95.312	ENSMZEG00005020500	arl4cb	100	95.312	Maylandia_zebra
ENSG00000188042	ARL4C	90	97.674	ENSMGAG00000016127	ARL4C	99	97.674	Meleagris_gallopavo
ENSG00000188042	ARL4C	100	100.000	ENSMICG00000017503	ARL4C	95	99.482	Microcebus_murinus
ENSG00000188042	ARL4C	100	100.000	ENSMOCG00000006232	Arl4c	100	100.000	Microtus_ochrogaster
ENSG00000188042	ARL4C	100	97.917	ENSMODG00000023112	ARL4C	100	97.917	Monodelphis_domestica
ENSG00000188042	ARL4C	100	95.312	ENSMALG00000011378	arl4cb	100	95.312	Monopterus_albus
ENSG00000188042	ARL4C	100	84.974	ENSMALG00000006786	-	97	84.974	Monopterus_albus
ENSG00000188042	ARL4C	100	100.000	MGP_CAROLIEiJ_G0014402	Arl4c	100	100.000	Mus_caroli
ENSG00000188042	ARL4C	100	100.000	ENSMUSG00000049866	Arl4c	100	100.000	Mus_musculus
ENSG00000188042	ARL4C	100	100.000	MGP_PahariEiJ_G0027638	Arl4c	100	100.000	Mus_pahari
ENSG00000188042	ARL4C	100	100.000	MGP_SPRETEiJ_G0015206	Arl4c	100	100.000	Mus_spretus
ENSG00000188042	ARL4C	100	100.000	ENSMPUG00000019267	ARL4C	100	100.000	Mustela_putorius_furo
ENSG00000188042	ARL4C	100	100.000	ENSNGAG00000012405	Arl4c	100	100.000	Nannospalax_galili
ENSG00000188042	ARL4C	97	96.257	ENSNBRG00000020745	arl4cb	94	96.257	Neolamprologus_brichardi
ENSG00000188042	ARL4C	92	83.708	ENSNBRG00000015182	-	96	84.211	Neolamprologus_brichardi
ENSG00000188042	ARL4C	100	98.958	ENSMEUG00000006551	ARL4C	99	96.985	Notamacropus_eugenii
ENSG00000188042	ARL4C	100	100.000	ENSODEG00000019668	ARL4C	100	100.000	Octodon_degus
ENSG00000188042	ARL4C	94	83.425	ENSONIG00000021039	arl4ca	98	83.938	Oreochromis_niloticus
ENSG00000188042	ARL4C	99	99.474	ENSOANG00000011765	ARL4C	99	99.474	Ornithorhynchus_anatinus
ENSG00000188042	ARL4C	100	100.000	ENSOCUG00000005758	ARL4C	100	100.000	Oryctolagus_cuniculus
ENSG00000188042	ARL4C	100	96.354	ENSORLG00000013843	arl4cb	100	96.354	Oryzias_latipes
ENSG00000188042	ARL4C	88	65.882	ENSORLG00000026726	-	95	65.000	Oryzias_latipes
ENSG00000188042	ARL4C	88	66.471	ENSORLG00020011692	-	95	65.556	Oryzias_latipes_hni
ENSG00000188042	ARL4C	100	96.354	ENSORLG00020007137	arl4cb	100	96.354	Oryzias_latipes_hni
ENSG00000188042	ARL4C	100	96.354	ENSORLG00015009897	arl4cb	100	96.354	Oryzias_latipes_hsok
ENSG00000188042	ARL4C	90	66.474	ENSORLG00015014008	-	97	65.027	Oryzias_latipes_hsok
ENSG00000188042	ARL4C	100	96.354	ENSOMEG00000007253	arl4cb	100	96.354	Oryzias_melastigma
ENSG00000188042	ARL4C	100	100.000	ENSOGAG00000034868	ARL4C	100	100.000	Otolemur_garnettii
ENSG00000188042	ARL4C	100	95.833	ENSOARG00000025194	ARL4C	100	95.833	Ovis_aries
ENSG00000188042	ARL4C	100	100.000	ENSPPAG00000002191	ARL4C	100	100.000	Pan_paniscus
ENSG00000188042	ARL4C	100	100.000	ENSPPRG00000016572	ARL4C	100	100.000	Panthera_pardus
ENSG00000188042	ARL4C	100	100.000	ENSPTIG00000011404	ARL4C	98	98.985	Panthera_tigris_altaica
ENSG00000188042	ARL4C	100	100.000	ENSPTRG00000013065	ARL4C	100	100.000	Pan_troglodytes
ENSG00000188042	ARL4C	100	100.000	ENSPANG00000006874	ARL4C	99	100.000	Papio_anubis
ENSG00000188042	ARL4C	100	94.271	ENSPKIG00000020450	arl4cb	100	94.271	Paramormyrops_kingsleyae
ENSG00000188042	ARL4C	100	96.354	ENSPKIG00000008422	ARL4C	100	96.354	Paramormyrops_kingsleyae
ENSG00000188042	ARL4C	95	78.689	ENSPMGG00000014369	-	93	78.689	Periophthalmus_magnuspinnatus
ENSG00000188042	ARL4C	100	100.000	ENSPEMG00000006610	Arl4c	100	100.000	Peromyscus_maniculatus_bairdii
ENSG00000188042	ARL4C	100	98.958	ENSPCIG00000003836	ARL4C	100	98.958	Phascolarctos_cinereus
ENSG00000188042	ARL4C	94	95.000	ENSPFOG00000020283	arl4cb	99	94.792	Poecilia_formosa
ENSG00000188042	ARL4C	94	95.000	ENSPLAG00000007735	arl4cb	99	94.792	Poecilia_latipinna
ENSG00000188042	ARL4C	91	96.000	ENSPMEG00000007028	arl4cb	94	95.722	Poecilia_mexicana
ENSG00000188042	ARL4C	100	79.793	ENSPREG00000021699	-	100	79.793	Poecilia_reticulata
ENSG00000188042	ARL4C	100	94.792	ENSPREG00000015645	arl4cb	99	94.792	Poecilia_reticulata
ENSG00000188042	ARL4C	100	100.000	ENSPPYG00000013299	ARL4C	99	100.000	Pongo_abelii
ENSG00000188042	ARL4C	100	100.000	ENSPCOG00000028187	ARL4C	94	100.000	Propithecus_coquereli
ENSG00000188042	ARL4C	100	95.312	ENSPNYG00000012693	arl4cb	100	95.312	Pundamilia_nyererei
ENSG00000188042	ARL4C	94	81.622	ENSPNYG00000021646	-	99	82.234	Pundamilia_nyererei
ENSG00000188042	ARL4C	100	93.229	ENSPNAG00000028458	arl4cb	100	93.229	Pygocentrus_nattereri
ENSG00000188042	ARL4C	100	69.271	ENSPNAG00000022337	-	100	69.271	Pygocentrus_nattereri
ENSG00000188042	ARL4C	100	100.000	ENSRBIG00000032960	-	99	100.000	Rhinopithecus_bieti
ENSG00000188042	ARL4C	100	100.000	ENSRROG00000029871	ARL4C	99	100.000	Rhinopithecus_roxellana
ENSG00000188042	ARL4C	100	100.000	ENSSBOG00000033162	ARL4C	99	100.000	Saimiri_boliviensis_boliviensis
ENSG00000188042	ARL4C	97	95.722	ENSSFOG00015018615	ARL4C	95	95.722	Scleropages_formosus
ENSG00000188042	ARL4C	98	96.825	ENSSFOG00015007064	arl4cb	95	96.825	Scleropages_formosus
ENSG00000188042	ARL4C	100	93.229	ENSSMAG00000016399	arl4cb	100	93.229	Scophthalmus_maximus
ENSG00000188042	ARL4C	100	83.938	ENSSMAG00000013072	-	99	83.938	Scophthalmus_maximus
ENSG00000188042	ARL4C	100	95.833	ENSSDUG00000012868	arl4cb	100	95.833	Seriola_dumerili
ENSG00000188042	ARL4C	100	95.833	ENSSLDG00000017889	arl4cb	100	95.833	Seriola_lalandi_dorsalis
ENSG00000188042	ARL4C	100	84.456	ENSSLDG00000012103	-	97	84.456	Seriola_lalandi_dorsalis
ENSG00000188042	ARL4C	97	84.574	ENSSPAG00000022062	-	94	84.574	Stegastes_partitus
ENSG00000188042	ARL4C	97	97.326	ENSSPAG00000010587	arl4cb	94	97.326	Stegastes_partitus
ENSG00000188042	ARL4C	100	100.000	ENSSSCG00000034293	ARL4C	100	100.000	Sus_scrofa
ENSG00000188042	ARL4C	100	97.917	ENSTGUG00000003095	ARL4C	100	97.917	Taeniopygia_guttata
ENSG00000188042	ARL4C	100	93.229	ENSTRUG00000003085	arl4cb	100	93.229	Takifugu_rubripes
ENSG00000188042	ARL4C	94	81.768	ENSTRUG00000003183	-	99	82.383	Takifugu_rubripes
ENSG00000188042	ARL4C	94	77.348	ENSTNIG00000003426	-	96	78.238	Tetraodon_nigroviridis
ENSG00000188042	ARL4C	100	100.000	ENSUAMG00000007888	ARL4C	100	100.000	Ursus_americanus
ENSG00000188042	ARL4C	96	87.500	ENSUMAG00000013306	ARL4C	87	87.500	Ursus_maritimus
ENSG00000188042	ARL4C	100	100.000	ENSVVUG00000025311	ARL4C	100	100.000	Vulpes_vulpes
ENSG00000188042	ARL4C	100	92.188	ENSXETG00000010915	arl4c	99	92.188	Xenopus_tropicalis
ENSG00000188042	ARL4C	100	94.792	ENSXCOG00000016119	arl4cb	96	94.792	Xiphophorus_couchianus
ENSG00000188042	ARL4C	96	82.162	ENSXCOG00000003923	-	91	82.162	Xiphophorus_couchianus
ENSG00000188042	ARL4C	95	81.421	ENSXMAG00000000086	-	93	81.421	Xiphophorus_maculatus
ENSG00000188042	ARL4C	98	95.238	ENSXMAG00000020364	arl4cb	96	95.238	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003924	GTPase activity	10462049.	TAS	Function
GO:0005515	protein binding	17398095.	IPI	Function
GO:0005525	GTP binding	21873635.	IBA	Function
GO:0005634	nucleus	10462049.	TAS	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	19409876.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005886	plasma membrane	21873635.	IBA	Component
GO:0005886	plasma membrane	17398095.	IDA	Component
GO:0006886	intracellular protein transport	21873635.	IBA	Process
GO:0016192	vesicle-mediated transport	21873635.	IBA	Process
GO:0030175	filopodium	-	IEA	Component
GO:0032456	endocytic recycling	21873635.	IBA	Process
GO:0032456	endocytic recycling	19409876.	IDA	Process
GO:0043014	alpha-tubulin binding	19409876.	IDA	Function

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
25486429	Arl4c expression in colorectal and lung cancers promotes tumorigenesis and may represent a novel therapeutic target.	Oncogene	2015 Sep 10	Fujii S	doi: 10.1038/onc.2014.402
29270876	Identification of ARL4C as a Peritoneal Dissemination-Associated Gene and Its Clinical Significance in Gastric Cancer.	Ann Surg Oncol	2018 Mar	Hu Q	doi: 10.1245/s10434-017-6292-6

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr2	234496515	Silent	NA	A24A	0.08
BLCA	chr2	234495890	3'UTR	novel		0.26
BLCA	chr2	234495961	3'UTR	novel		0.1
BLCA	chr2	234495790	3'UTR	novel		0.59
BLCA	chr2	234496079	Missense_Mutation	novel	E170K	0.24
BLCA	chr2	234496095	Silent	NA	I164I	0.24
BLCA	chr2	234496555	Missense_Mutation	novel	F11Y	0.22
CESC	chr2	234494459	3'UTR	novel		0.26
CESC	chr2	234493193	3'UTR	novel		0.36
COAD	chr2	234496269	Silent	novel	T106T	0.19
COAD	chr2	234495974	3'UTR	novel		0.28
COAD	chr2	234496374	Silent	NA	G71G	0.31
COAD	chr2	234496296	Silent	novel	D97D	0.07
ESCA	chr2	234496437	Silent	novel	E50E	0.16
ESCA	chr2	234495152	3'UTR	novel		0.67
ESCA	chr2	234496479	Silent	novel	N36N	0.28
GBM	chr2	234496012	Missense_Mutation	novel	R192Q	0.22
HNSC	chr2	234496166	Missense_Mutation	novel	E141K	0.2
HNSC	chr2	234496125	Silent	novel	T154T	0.17
KICH	chr2	234496042	Missense_Mutation	NA	R182H	0.21
LUAD	chr2	234495762	3'UTR	novel		0.13
LUAD	chr2	234496205	In_Frame_Del	novel	L122_K128delinsQ	0.06	MMR_HSR1
LUAD	chr2	234496180	Missense_Mutation	novel	P136L	0.15
LUSC	chr2	234496220	Missense_Mutation	novel	L123V	0.11	MMR_HSR1
LUSC	chr2	234495958	3'UTR	novel		0.11
LUSC	chr2	234496560	Silent	novel	S9S	0.12
LUSC	chr2	234496029	Silent	novel	L186L	0.31
LUSC	chr2	234496047	Silent	novel	L180L	0.13
MESO	chr2	234496113	Missense_Mutation	novel	Q158H	0.44
OV	chr2	234496575	Silent	novel	I4I	0.55
OV	chr2	234496024	Missense_Mutation	NA	Q188P	0.12
PAAD	chr2	234495859	3'UTR	novel		0.16
PAAD	chr2	234496027	Missense_Mutation	novel	K187T	0.17
PAAD	chr2	234496091	Missense_Mutation	novel	E166Q	0.45
PRAD	chr2	234496436	Nonsense_Mutation	NA	K51*	0.23	MMR_HSR1
READ	chr2	234496223	Missense_Mutation	novel	L122M	0.46	MMR_HSR1
SARC	chr2	234495140	3'UTR	novel		0.38
SARC	chr2	234496260	Missense_Mutation	novel	H109Q	0.1	MMR_HSR1
SARC	chr2	234494868	3'UTR	novel		0.15
SKCM	chr2	234495764	3'UTR	novel		0.32
SKCM	chr2	234496145	Missense_Mutation	novel	E148K	0.34
SKCM	chr2	234495771	3'UTR	novel		0.59
STAD	chr2	234495854	3'UTR	novel		0.1
STAD	chr2	234495814	3'UTR	novel		0.26
STAD	chr2	234496581	Silent	novel	G2G	0.29
STAD	chr2	234495777	3'UTR	novel		0.15
STAD	chr2	234496153	Missense_Mutation	NA	A145V	0.19
STAD	chr2	234496440	Silent	NA	T49T	0.22
UCEC	chr2	234494360	3'UTR	novel		0.34
UCEC	chr2	234493541	3'UTR	novel		0.39
UCEC	chr2	234493929	3'UTR	novel		0.31
UCEC	chr2	234494060	3'UTR	novel		0.5
UCEC	chr2	234494879	3'UTR	novel		0.52
UCEC	chr2	234494607	3'UTR	novel		0.67
UCEC	chr2	234493561	3'UTR	novel		0.48
UCEC	chr2	234496151	Silent	novel	L146L	0.36
UCEC	chr2	234493766	3'UTR	novel		0.45
UCEC	chr2	234495140	3'UTR	novel		0.44
UCEC	chr2	234493766	3'UTR	novel		0.38
UCEC	chr2	234493132	3'UTR	novel		0.51
UCEC	chr2	234495450	3'UTR	novel		0.26
UCEC	chr2	234493057	3'UTR	novel		0.13
UCEC	chr2	234494255	3'UTR	novel		0.51
UCEC	chr2	234494946	3'UTR	novel		0.49
UCEC	chr2	234495502	3'UTR	novel		0.29
UCEC	chr2	234494126	3'UTR	novel		0.38
UCEC	chr2	234493955	3'UTR	novel		0.43
UCEC	chr2	234495045	3'UTR	novel		0.33
UCEC	chr2	234496631	5'UTR	novel		0.15
UCEC	chr2	234493193	3'UTR	novel		0.37
UCEC	chr2	234495578	3'UTR	novel		0.33
UCEC	chr2	234493615	3'UTR	novel		0.54
UCEC	chr2	234495698	3'UTR	novel		0.36
UCEC	chr2	234495854	3'UTR	rs757163818		0.26
UCEC	chr2	234493766	3'UTR	novel		0.37
UCEC	chr2	234496203	Silent	rs764670514	K128K	0.13
UCEC	chr2	234496264	Missense_Mutation	novel	L108P	0.3	MMR_HSR1
UCEC	chr2	234493831	3'UTR	novel		0.36
UCEC	chr2	234495719	3'UTR	novel		0.41
UCEC	chr2	234494897	3'UTR	novel		0.41
UCEC	chr2	234495828	3'UTR	novel		0.47
UCEC	chr2	234496042	Missense_Mutation	NA	R182H	0.24
UCEC	chr2	234496499	Missense_Mutation	novel	L30F	0.44	MMR_HSR1
UCEC	chr2	234493228	3'UTR	novel		0.43
UCEC	chr2	234494384	3'UTR	novel		0.17
UCEC	chr2	234494368	3'UTR	novel		0.28
UCEC	chr2	234494531	3'UTR	novel		0.3
UCEC	chr2	234496281	Silent	novel	E102E	0.21
UCEC	chr2	234495996	3'UTR	novel		0.35
UCEC	chr2	234494468	3'UTR	novel		0.44

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	DEL	0.4265	2.0711e-36
BRCA	DEL	0.2074	2.4898e-11
CESC	DEL	0.3695	3.4658e-41
HNSC	DEL	0.2146	1.278e-25
KIRP	DEL	0.0382	5.174e-05
LIHC	DEL	0.1162	0.0022356
LUSC	DEL	0.2655	1.3904e-19
MESO	DEL	0.1034	0.014499
OV	DEL	0.2228	7.0161e-09
PAAD	AMP	0.0707	0.1091
PAAD	DEL	0.0435	0.2014
SARC	DEL	0.3658	7.1647e-24
TGCT	DEL	0.06	0.062762
THCA	DEL	0.024	0.040844
THYM	DEL	0.0325	0.10691
UCEC	DEL	0.0668	0.00045104
UVM	DEL	0.0375	0.024639

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0042	Kaplan-Meier Survival Analysis
KIRC	0.00011	Kaplan-Meier Survival Analysis
MESO	0.017	Kaplan-Meier Survival Analysis
ACC	0.049	Kaplan-Meier Survival Analysis
HNSC	0.0063	Kaplan-Meier Survival Analysis
SKCM	0.0001	Kaplan-Meier Survival Analysis
KIRP	0.0016	Kaplan-Meier Survival Analysis
COAD	0.0019	Kaplan-Meier Survival Analysis
PAAD	0.0072	Kaplan-Meier Survival Analysis
BLCA	0.0001	Kaplan-Meier Survival Analysis
UCEC	0.00015	Kaplan-Meier Survival Analysis
GBM	0.0049	Kaplan-Meier Survival Analysis
UVM	0.0062	Kaplan-Meier Survival Analysis
OV	0.039	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742