EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000188976 (Gene tree)
Gene ID: 26155
Gene Symbol: NOC2L
Alias: DKFZP564C186|NET7|NET15|NIR|PPP1R112
Full Name: NOC2 like nucleolar associated transcriptional repressor
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 15,107 bases
Position: chr1:944,203-959,309
Accession: 24517
RBP type: canonical RBP
Summary: Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. NOC2L represents a novel HDAC-independent inhibitor of histone acetyltransferase (INHAT) (Hublitz et al., 2005 [PubMed 16322561]).[supplied by OMIM, Mar 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000317992	Noc2	PF03715.13	3.7e-119	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
22363708	Transcriptional repressor NIR functions in the ribosome RNA processing of both 40S and 60S subunits.	PLoS One	2012	Wu J	doi: 10.1371/journal.pone.0031692

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000487214	NOC2L-205	865	-	-	- (aa)	-	-
ENST00000469563	NOC2L-202	878	-	-	- (aa)	-	-
ENST00000483767	NOC2L-204	1611	-	-	- (aa)	-	-
ENST00000477976	NOC2L-203	4201	-	-	- (aa)	-	-
ENST00000327044	NOC2L-201	2790	-	ENSP00000317992	749 (aa)	-	Q9Y3T9
ENST00000496938	NOC2L-206	149	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000188976's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000188976's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000188976	NOC2L	99	56.789	ENSAPOG00000019587	noc2l	99	55.698	Acanthochromis_polyacanthus
ENSG00000188976	NOC2L	100	78.667	ENSAMEG00000016516	NOC2L	100	78.667	Ailuropoda_melanoleuca
ENSG00000188976	NOC2L	99	54.011	ENSACIG00000004084	noc2l	90	59.027	Amphilophus_citrinellus
ENSG00000188976	NOC2L	91	59.590	ENSAOCG00000019674	noc2l	95	59.448	Amphiprion_ocellaris
ENSG00000188976	NOC2L	99	53.083	ENSAPEG00000021569	noc2l	99	55.428	Amphiprion_percula
ENSG00000188976	NOC2L	99	57.050	ENSATEG00000018407	noc2l	99	57.143	Anabas_testudineus
ENSG00000188976	NOC2L	84	65.719	ENSAPLG00000008755	NOC2L	94	64.969	Anas_platyrhynchos
ENSG00000188976	NOC2L	82	62.319	ENSACAG00000008492	NOC2L	99	62.036	Anolis_carolinensis
ENSG00000188976	NOC2L	70	89.847	ENSANAG00000029524	NOC2L	77	89.847	Aotus_nancymaae
ENSG00000188976	NOC2L	86	60.000	ENSACLG00000026116	noc2l	99	56.653	Astatotilapia_calliptera
ENSG00000188976	NOC2L	99	55.046	ENSAMXG00000012865	noc2l	99	55.046	Astyanax_mexicanus
ENSG00000188976	NOC2L	100	78.723	ENSBTAG00000016528	NOC2L	100	78.191	Bos_taurus
ENSG00000188976	NOC2L	100	90.133	ENSCJAG00000011380	NOC2L	100	90.667	Callithrix_jacchus
ENSG00000188976	NOC2L	100	76.671	ENSCAFG00000019369	NOC2L	100	76.610	Canis_familiaris
ENSG00000188976	NOC2L	100	76.812	ENSCAFG00020011712	NOC2L	100	76.680	Canis_lupus_dingo
ENSG00000188976	NOC2L	100	78.249	ENSCHIG00000017187	NOC2L	100	78.117	Capra_hircus
ENSG00000188976	NOC2L	92	80.523	ENSTSYG00000032696	NOC2L	100	80.523	Carlito_syrichta
ENSG00000188976	NOC2L	78	67.851	ENSCAPG00000006877	NOC2L	100	68.020	Cavia_aperea
ENSG00000188976	NOC2L	100	76.285	ENSCPOG00000007964	NOC2L	100	76.153	Cavia_porcellus
ENSG00000188976	NOC2L	100	90.426	ENSCCAG00000035002	NOC2L	100	90.293	Cebus_capucinus
ENSG00000188976	NOC2L	92	92.374	ENSCATG00000034591	NOC2L	99	92.086	Cercocebus_atys
ENSG00000188976	NOC2L	100	76.852	ENSCLAG00000010210	NOC2L	100	76.455	Chinchilla_lanigera
ENSG00000188976	NOC2L	100	91.931	ENSCSAG00000000664	NOC2L	100	91.667	Chlorocebus_sabaeus
ENSG00000188976	NOC2L	99	60.052	ENSCPBG00000022124	NOC2L	99	60.000	Chrysemys_picta_bellii
ENSG00000188976	NOC2L	91	41.159	ENSCING00000005419	-	90	41.449	Ciona_intestinalis
ENSG00000188976	NOC2L	92	93.759	ENSCANG00000034286	NOC2L	100	93.759	Colobus_angolensis_palliatus
ENSG00000188976	NOC2L	100	76.494	ENSCGRG00001012249	Noc2l	100	75.931	Cricetulus_griseus_chok1gshd
ENSG00000188976	NOC2L	80	78.559	ENSCGRG00000002320	Noc2l	100	78.559	Cricetulus_griseus_crigri
ENSG00000188976	NOC2L	99	55.979	ENSCSEG00000006426	noc2l	99	56.693	Cynoglossus_semilaevis
ENSG00000188976	NOC2L	89	60.896	ENSCVAG00000006633	noc2l	91	60.117	Cyprinodon_variegatus
ENSG00000188976	NOC2L	99	55.395	ENSDARG00000001754	noc2l	99	62.366	Danio_rerio
ENSG00000188976	NOC2L	100	78.013	ENSDNOG00000039671	NOC2L	93	77.895	Dasypus_novemcinctus
ENSG00000188976	NOC2L	99	75.234	ENSDORG00000013746	Noc2l	100	78.392	Dipodomys_ordii
ENSG00000188976	NOC2L	83	35.988	FBgn0032925	CG9246	83	36.364	Drosophila_melanogaster
ENSG00000188976	NOC2L	70	70.968	ENSETEG00000010778	-	61	77.143	Echinops_telfairi
ENSG00000188976	NOC2L	99	45.076	ENSEBUG00000006083	noc2l	99	45.732	Eptatretus_burgeri
ENSG00000188976	NOC2L	99	79.088	ENSEASG00005015108	NOC2L	86	79.017	Equus_asinus_asinus
ENSG00000188976	NOC2L	99	78.877	ENSECAG00000023976	NOC2L	87	79.073	Equus_caballus
ENSG00000188976	NOC2L	97	64.883	ENSEEUG00000013339	NOC2L	100	64.507	Erinaceus_europaeus
ENSG00000188976	NOC2L	89	59.851	ENSELUG00000008668	noc2l	100	58.197	Esox_lucius
ENSG00000188976	NOC2L	98	78.032	ENSFCAG00000003356	NOC2L	100	77.881	Felis_catus
ENSG00000188976	NOC2L	80	64.573	ENSFALG00000007392	NOC2L	100	64.573	Ficedula_albicollis
ENSG00000188976	NOC2L	99	76.892	ENSFDAG00000017623	NOC2L	99	77.025	Fukomys_damarensis
ENSG00000188976	NOC2L	99	57.987	ENSFHEG00000005783	noc2l	99	57.839	Fundulus_heteroclitus
ENSG00000188976	NOC2L	99	52.603	ENSGMOG00000000675	noc2l	99	52.005	Gadus_morhua
ENSG00000188976	NOC2L	100	59.974	ENSGALG00000002222	NOC2L	100	60.536	Gallus_gallus
ENSG00000188976	NOC2L	99	56.860	ENSGAFG00000000312	noc2l	99	56.954	Gambusia_affinis
ENSG00000188976	NOC2L	99	56.839	ENSGACG00000007367	noc2l	99	56.764	Gasterosteus_aculeatus
ENSG00000188976	NOC2L	99	60.441	ENSGAGG00000011477	NOC2L	99	60.571	Gopherus_agassizii
ENSG00000188976	NOC2L	80	93.467	ENSGGOG00000025539	-	100	93.467	Gorilla_gorilla
ENSG00000188976	NOC2L	100	97.730	ENSGGOG00000007732	NOC2L	100	97.730	Gorilla_gorilla
ENSG00000188976	NOC2L	86	60.000	ENSHBUG00000021479	noc2l	99	56.653	Haplochromis_burtoni
ENSG00000188976	NOC2L	100	75.862	ENSHGLG00000006852	NOC2L	100	75.862	Heterocephalus_glaber_female
ENSG00000188976	NOC2L	100	75.862	ENSHGLG00100008514	NOC2L	100	75.862	Heterocephalus_glaber_male
ENSG00000188976	NOC2L	99	53.977	ENSHCOG00000005732	noc2l	99	54.581	Hippocampus_comes
ENSG00000188976	NOC2L	99	56.771	ENSIPUG00000020920	noc2l	99	56.088	Ictalurus_punctatus
ENSG00000188976	NOC2L	90	80.386	ENSSTOG00000009911	NOC2L	100	80.090	Ictidomys_tridecemlineatus
ENSG00000188976	NOC2L	100	76.517	ENSJJAG00000022658	Noc2l	100	76.486	Jaculus_jaculus
ENSG00000188976	NOC2L	99	56.356	ENSKMAG00000016552	noc2l	99	55.917	Kryptolebias_marmoratus
ENSG00000188976	NOC2L	99	57.087	ENSLBEG00000020869	noc2l	100	59.802	Labrus_bergylta
ENSG00000188976	NOC2L	99	54.822	ENSLOCG00000007227	noc2l	86	59.211	Lepisosteus_oculatus
ENSG00000188976	NOC2L	68	71.209	ENSLAFG00000025891	-	100	70.825	Loxodonta_africana
ENSG00000188976	NOC2L	100	92.450	ENSMFAG00000032890	NOC2L	100	92.715	Macaca_fascicularis
ENSG00000188976	NOC2L	100	92.667	ENSMMUG00000015800	NOC2L	100	92.800	Macaca_mulatta
ENSG00000188976	NOC2L	100	91.711	ENSMNEG00000044359	NOC2L	100	91.842	Macaca_nemestrina
ENSG00000188976	NOC2L	99	91.788	ENSMLEG00000028428	NOC2L	99	91.523	Mandrillus_leucophaeus
ENSG00000188976	NOC2L	99	57.467	ENSMAMG00000009952	noc2l	100	59.801	Mastacembelus_armatus
ENSG00000188976	NOC2L	86	60.000	ENSMZEG00005013227	noc2l	99	56.653	Maylandia_zebra
ENSG00000188976	NOC2L	91	61.718	ENSMGAG00000003512	NOC2L	99	57.326	Meleagris_gallopavo
ENSG00000188976	NOC2L	100	76.627	ENSMAUG00000012860	Noc2l	100	75.995	Mesocricetus_auratus
ENSG00000188976	NOC2L	100	80.739	ENSMICG00000008289	NOC2L	100	80.556	Microcebus_murinus
ENSG00000188976	NOC2L	100	73.733	ENSMOCG00000019617	Noc2l	100	78.894	Microtus_ochrogaster
ENSG00000188976	NOC2L	92	58.721	ENSMMOG00000009136	noc2l	95	58.526	Mola_mola
ENSG00000188976	NOC2L	96	55.907	ENSMODG00000018641	-	79	57.842	Monodelphis_domestica
ENSG00000188976	NOC2L	100	75.564	MGP_CAROLIEiJ_G0026926	Noc2l	100	77.722	Mus_caroli
ENSG00000188976	NOC2L	100	74.147	ENSMUSG00000095567	Noc2l	100	76.884	Mus_musculus
ENSG00000188976	NOC2L	100	76.228	MGP_PahariEiJ_G0029275	Noc2l	100	78.559	Mus_pahari
ENSG00000188976	NOC2L	100	74.055	MGP_SPRETEiJ_G0027921	Noc2l	100	77.722	Mus_spretus
ENSG00000188976	NOC2L	99	75.393	ENSMPUG00000013830	NOC2L	99	75.393	Mustela_putorius_furo
ENSG00000188976	NOC2L	93	77.479	ENSMLUG00000008025	NOC2L	100	77.904	Myotis_lucifugus
ENSG00000188976	NOC2L	100	76.533	ENSNGAG00000015129	Noc2l	100	79.564	Nannospalax_galili
ENSG00000188976	NOC2L	100	90.387	ENSNLEG00000000013	NOC2L	100	90.254	Nomascus_leucogenys
ENSG00000188976	NOC2L	100	84.646	ENSNLEG00000010565	-	100	85.047	Nomascus_leucogenys
ENSG00000188976	NOC2L	92	63.081	ENSMEUG00000000693	NOC2L	100	62.209	Notamacropus_eugenii
ENSG00000188976	NOC2L	87	68.153	ENSOPRG00000008154	-	90	68.153	Ochotona_princeps
ENSG00000188976	NOC2L	80	77.219	ENSODEG00000009486	NOC2L	100	77.219	Octodon_degus
ENSG00000188976	NOC2L	99	55.817	ENSONIG00000002402	noc2l	99	55.226	Oreochromis_niloticus
ENSG00000188976	NOC2L	84	75.725	ENSOCUG00000011036	NOC2L	99	76.110	Oryctolagus_cuniculus
ENSG00000188976	NOC2L	99	55.906	ENSORLG00000005561	noc2l	100	57.789	Oryzias_latipes
ENSG00000188976	NOC2L	99	55.643	ENSORLG00020000314	noc2l	99	56.863	Oryzias_latipes_hni
ENSG00000188976	NOC2L	91	58.798	ENSORLG00015000113	noc2l	95	58.884	Oryzias_latipes_hsok
ENSG00000188976	NOC2L	99	55.308	ENSOMEG00000022096	noc2l	100	57.166	Oryzias_melastigma
ENSG00000188976	NOC2L	100	79.233	ENSOGAG00000024987	NOC2L	100	78.968	Otolemur_garnettii
ENSG00000188976	NOC2L	100	78.382	ENSOARG00000007909	NOC2L	100	78.382	Ovis_aries
ENSG00000188976	NOC2L	100	85.087	ENSPPAG00000035688	-	100	84.554	Pan_paniscus
ENSG00000188976	NOC2L	98	77.628	ENSPPRG00000023063	NOC2L	100	77.483	Panthera_pardus
ENSG00000188976	NOC2L	97	71.798	ENSPTIG00000004690	NOC2L	99	72.021	Panthera_tigris_altaica
ENSG00000188976	NOC2L	92	97.110	ENSPTRG00000050965	-	100	97.110	Pan_troglodytes
ENSG00000188976	NOC2L	100	86.649	ENSPTRG00000050461	-	100	86.649	Pan_troglodytes
ENSG00000188976	NOC2L	100	98.131	ENSPTRG00000022530	NOC2L	100	98.131	Pan_troglodytes
ENSG00000188976	NOC2L	100	92.133	ENSPANG00000024464	NOC2L	100	92.400	Papio_anubis
ENSG00000188976	NOC2L	99	55.336	ENSPKIG00000013389	noc2l	100	57.825	Paramormyrops_kingsleyae
ENSG00000188976	NOC2L	90	64.012	ENSPSIG00000012303	NOC2L	98	64.012	Pelodiscus_sinensis
ENSG00000188976	NOC2L	99	56.124	ENSPMGG00000009445	noc2l	99	55.749	Periophthalmus_magnuspinnatus
ENSG00000188976	NOC2L	100	76.393	ENSPEMG00000010309	Noc2l	100	75.830	Peromyscus_maniculatus_bairdii
ENSG00000188976	NOC2L	91	67.811	ENSPCIG00000001294	-	97	68.201	Phascolarctos_cinereus
ENSG00000188976	NOC2L	99	53.927	ENSPFOG00000019047	noc2l	99	54.881	Poecilia_formosa
ENSG00000188976	NOC2L	99	56.110	ENSPLAG00000020462	noc2l	99	57.219	Poecilia_latipinna
ENSG00000188976	NOC2L	99	56.184	ENSPMEG00000005655	noc2l	99	56.897	Poecilia_mexicana
ENSG00000188976	NOC2L	74	60.862	ENSPREG00000015280	noc2l	94	62.949	Poecilia_reticulata
ENSG00000188976	NOC2L	90	90.767	ENSPPYG00000002028	NOC2L	100	90.767	Pongo_abelii
ENSG00000188976	NOC2L	82	74.434	ENSPCAG00000013364	NOC2L	99	74.351	Procavia_capensis
ENSG00000188976	NOC2L	100	79.735	ENSPCOG00000019653	NOC2L	100	80.556	Propithecus_coquereli
ENSG00000188976	NOC2L	50	82.857	ENSPVAG00000010828	-	64	82.857	Pteropus_vampyrus
ENSG00000188976	NOC2L	89	59.820	ENSPNYG00000006439	noc2l	99	55.979	Pundamilia_nyererei
ENSG00000188976	NOC2L	99	57.124	ENSPNAG00000019855	noc2l	99	56.430	Pygocentrus_nattereri
ENSG00000188976	NOC2L	86	75.428	ENSRNOG00000021392	Noc2l	95	76.911	Rattus_norvegicus
ENSG00000188976	NOC2L	100	93.122	ENSRBIG00000037760	NOC2L	99	92.857	Rhinopithecus_bieti
ENSG00000188976	NOC2L	100	92.999	ENSRROG00000024251	NOC2L	99	92.602	Rhinopithecus_roxellana
ENSG00000188976	NOC2L	75	30.900	YOR206W	-	79	31.046	Saccharomyces_cerevisiae
ENSG00000188976	NOC2L	100	89.600	ENSSBOG00000020276	NOC2L	100	88.800	Saimiri_boliviensis_boliviensis
ENSG00000188976	NOC2L	99	57.256	ENSSFOG00015006109	noc2l	99	56.860	Scleropages_formosus
ENSG00000188976	NOC2L	99	57.784	ENSSMAG00000018439	noc2l	99	57.520	Scophthalmus_maximus
ENSG00000188976	NOC2L	99	58.344	ENSSDUG00000007854	noc2l	97	59.433	Seriola_dumerili
ENSG00000188976	NOC2L	99	58.081	ENSSLDG00000001353	noc2l	100	57.181	Seriola_lalandi_dorsalis
ENSG00000188976	NOC2L	82	72.327	ENSSARG00000006538	NOC2L	90	70.909	Sorex_araneus
ENSG00000188976	NOC2L	91	58.978	ENSSPUG00000018958	NOC2L	93	58.686	Sphenodon_punctatus
ENSG00000188976	NOC2L	100	78.486	ENSSSCG00000023973	NOC2L	100	78.220	Sus_scrofa
ENSG00000188976	NOC2L	92	65.893	ENSTGUG00000003958	-	100	64.740	Taeniopygia_guttata
ENSG00000188976	NOC2L	52	54.381	ENSTGUG00000014842	-	100	54.381	Taeniopygia_guttata
ENSG00000188976	NOC2L	95	56.516	ENSTRUG00000009437	noc2l	98	58.106	Takifugu_rubripes
ENSG00000188976	NOC2L	98	55.366	ENSTNIG00000015158	noc2l	99	56.005	Tetraodon_nigroviridis
ENSG00000188976	NOC2L	100	74.567	ENSTTRG00000003188	NOC2L	99	74.567	Tursiops_truncatus
ENSG00000188976	NOC2L	64	80.745	ENSUAMG00000027519	NOC2L	87	80.538	Ursus_americanus
ENSG00000188976	NOC2L	100	77.467	ENSUMAG00000002714	NOC2L	100	77.927	Ursus_maritimus
ENSG00000188976	NOC2L	100	76.610	ENSVVUG00000003648	NOC2L	100	76.478	Vulpes_vulpes
ENSG00000188976	NOC2L	92	58.601	ENSXCOG00000004715	noc2l	99	57.221	Xiphophorus_couchianus
ENSG00000188976	NOC2L	99	56.464	ENSXMAG00000003835	noc2l	99	57.219	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	21873635.	IBA	Process
GO:0000122	negative regulation of transcription by RNA polymerase II	20123734.20959462.	IDA	Process
GO:0002903	negative regulation of B cell apoptotic process	20959462.	IMP	Process
GO:0003682	chromatin binding	16322561.20123734.	IDA	Function
GO:0003714	transcription corepressor activity	21873635.	IBA	Function
GO:0003714	transcription corepressor activity	16322561.	IDA	Function
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	16322561.20123734.20959462.21078624.	IPI	Function
GO:0005634	nucleus	16322561.20959462.	IDA	Component
GO:0005654	nucleoplasm	21873635.	IBA	Component
GO:0005654	nucleoplasm	20123734.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005730	nucleolus	20123734.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006915	apoptotic process	-	IEA	Process
GO:0030690	Noc1p-Noc2p complex	21873635.	IBA	Component
GO:0030691	Noc2p-Noc3p complex	21873635.	IBA	Component
GO:0031491	nucleosome binding	16322561.	IDA	Function
GO:0031497	chromatin assembly	16322561.	IDA	Process
GO:0034644	cellular response to UV	20959462.	IDA	Process
GO:0035067	negative regulation of histone acetylation	21873635.	IBA	Process
GO:0035067	negative regulation of histone acetylation	16322561.	IDA	Process
GO:0042273	ribosomal large subunit biogenesis	21873635.	IBA	Process
GO:0042393	histone binding	21873635.	IBA	Function
GO:0042393	histone binding	16322561.	IDA	Function
GO:0070491	repressing transcription factor binding	21873635.	IBA	Function
GO:0070491	repressing transcription factor binding	16322561.	IDA	Function
GO:1901796	regulation of signal transduction by p53 class mediator	-	TAS	Process
GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	16322561.	IMP	Process