EuRBPDB

Description

Ensembl ID: ENSG00000189190 (Gene tree)
Gene ID: 162966
Gene Symbol: ZNF600
Alias: KR-ZNF1|DKFZp686F06123
Full Name: zinc finger protein 600
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 83,687 bases
Position: chr19:52,749,942-52,833,628
Accession: 30951
RBP type: canonical RBP
Summary: ZNF600 (Zinc Finger Protein 600) is a Protein Coding gene. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA-binding transcription factor activity. An important paralog of this gene is ZNF611.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000344791	zf-C2H2	PF00096.26	6.3e-80	1	14
ENSP00000344791	zf-C2H2	PF00096.26	6.3e-80	2	14
ENSP00000344791	zf-C2H2	PF00096.26	6.3e-80	3	14
ENSP00000344791	zf-C2H2	PF00096.26	6.3e-80	4	14
ENSP00000344791	zf-C2H2	PF00096.26	6.3e-80	5	14
ENSP00000344791	zf-C2H2	PF00096.26	6.3e-80	6	14
ENSP00000344791	zf-C2H2	PF00096.26	6.3e-80	7	14
ENSP00000344791	zf-C2H2	PF00096.26	6.3e-80	8	14
ENSP00000344791	zf-C2H2	PF00096.26	6.3e-80	9	14
ENSP00000344791	zf-C2H2	PF00096.26	6.3e-80	10	14
ENSP00000344791	zf-C2H2	PF00096.26	6.3e-80	11	14
ENSP00000344791	zf-C2H2	PF00096.26	6.3e-80	12	14
ENSP00000344791	zf-C2H2	PF00096.26	6.3e-80	13	14
ENSP00000344791	zf-C2H2	PF00096.26	6.3e-80	14	14
ENSP00000497540	zf-C2H2	PF00096.26	4.9e-79	1	14
ENSP00000497540	zf-C2H2	PF00096.26	4.9e-79	2	14
ENSP00000497540	zf-C2H2	PF00096.26	4.9e-79	3	14
ENSP00000497540	zf-C2H2	PF00096.26	4.9e-79	4	14
ENSP00000497540	zf-C2H2	PF00096.26	4.9e-79	5	14
ENSP00000497540	zf-C2H2	PF00096.26	4.9e-79	6	14
ENSP00000497540	zf-C2H2	PF00096.26	4.9e-79	7	14
ENSP00000497540	zf-C2H2	PF00096.26	4.9e-79	8	14
ENSP00000497540	zf-C2H2	PF00096.26	4.9e-79	9	14
ENSP00000497540	zf-C2H2	PF00096.26	4.9e-79	10	14
ENSP00000497540	zf-C2H2	PF00096.26	4.9e-79	11	14
ENSP00000497540	zf-C2H2	PF00096.26	4.9e-79	12	14
ENSP00000497540	zf-C2H2	PF00096.26	4.9e-79	13	14
ENSP00000497540	zf-C2H2	PF00096.26	4.9e-79	14	14
ENSP00000344791	zf-met	PF12874.7	4.4e-11	1	3
ENSP00000344791	zf-met	PF12874.7	4.4e-11	2	3
ENSP00000344791	zf-met	PF12874.7	4.4e-11	3	3
ENSP00000497540	zf-met	PF12874.7	2.8e-10	1	3
ENSP00000497540	zf-met	PF12874.7	2.8e-10	2	3
ENSP00000497540	zf-met	PF12874.7	2.8e-10	3	3

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000647907	ZNF600-206	2608	-	ENSP00000497989	210 (aa)	-	-
ENST00000599893	ZNF600-205	600	-	-	- (aa)	-	-
ENST00000594028	ZNF600-202	506	-	-	- (aa)	-	-
ENST00000648893	ZNF600-207	2987	-	ENSP00000497895	204 (aa)	-	-
ENST00000648973	ZNF600-208	3645	XM_017026390	ENSP00000497540	791 (aa)	XP_016881879	UPI00001D818F
ENST00000598369	ZNF600-204	650	-	-	- (aa)	-	-
ENST00000338230	ZNF600-201	3829	-	ENSP00000344791	722 (aa)	-	Q6ZNG1
ENST00000597124	ZNF600-203	333	-	-	- (aa)	-	-

Gene Model

Pathways

Pathway ID	Pathway Name	Source
hsa05168	Herpes simplex virus 1 infection	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000189190	Platelet Function Tests	1.2797700E-005	-
ENSG00000189190	Phospholipids	9E-9	22359512

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000189190	rs10404486	19	52780882	?	Phospholipid levels (plasma)	22359512	[NR] % increase	0.8	EFO_0004639

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000189190	ZNF600	99	87.216	ENSCATG00000036192	-	99	87.216	Cercocebus_atys
ENSG00000189190	ZNF600	100	88.089	ENSCSAG00000019650	-	100	88.089	Chlorocebus_sabaeus
ENSG00000189190	ZNF600	99	86.525	ENSCANG00000042957	-	99	86.525	Colobus_angolensis_palliatus
ENSG00000189190	ZNF600	99	83.333	ENSGGOG00000000018	ZNF611	99	74.610	Gorilla_gorilla
ENSG00000189190	ZNF600	100	89.836	ENSGGOG00000023190	ZNF600	100	86.150	Gorilla_gorilla
ENSG00000189190	ZNF600	100	81.431	ENSMFAG00000030933	-	100	82.271	Macaca_fascicularis
ENSG00000189190	ZNF600	100	87.950	ENSMFAG00000033366	-	100	88.258	Macaca_fascicularis
ENSG00000189190	ZNF600	99	87.358	ENSMMUG00000006472	-	99	87.358	Macaca_mulatta
ENSG00000189190	ZNF600	100	88.089	ENSMMUG00000017044	-	100	88.092	Macaca_mulatta
ENSG00000189190	ZNF600	99	87.421	ENSMNEG00000045369	-	100	87.663	Macaca_nemestrina
ENSG00000189190	ZNF600	99	86.635	ENSMLEG00000038583	-	96	86.635	Mandrillus_leucophaeus
ENSG00000189190	ZNF600	99	87.801	ENSNLEG00000006047	-	100	87.801	Nomascus_leucogenys
ENSG00000189190	ZNF600	99	95.429	ENSPPAG00000033496	ZNF600	100	95.429	Pan_paniscus
ENSG00000189190	ZNF600	100	98.199	ENSPTRG00000011412	ZNF600	100	98.199	Pan_troglodytes
ENSG00000189190	ZNF600	100	81.431	ENSPANG00000010431	-	100	82.271	Papio_anubis
ENSG00000189190	ZNF600	100	88.089	ENSPANG00000020931	-	100	88.387	Papio_anubis
ENSG00000189190	ZNF600	99	86.164	ENSPPYG00000029892	-	100	86.792	Pongo_abelii
ENSG00000189190	ZNF600	100	87.358	ENSRROG00000037435	-	100	87.358	Rhinopithecus_roxellana

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0005634	nucleus	-	IEA	Component
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0046872	metal ion binding	-	IEA	Function