EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000196455 (Gene tree)
Gene ID: 30849
Gene Symbol: PIK3R4
Alias: VPS15|p150
Full Name: phosphoinositide-3-kinase regulatory subunit 4
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 67,919 bases
Position: chr3:130,678,934-130,746,852
Accession: 8982
RBP type: non-canonical RBP
Summary: (Phosphoinositide-3-Kinase Regulatory Subunit 4) is a Protein Coding gene. Diseases associated with PIK3R4 include Danon Disease. Among its related pathways are PEDF Induced Signaling and CNTF Signaling. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and binding.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000356763	PIK3R4-201	5015	-	ENSP00000349205	1358 (aa)	-	Q99570
ENST00000512430	PIK3R4-207	579	-	ENSP00000422767	126 (aa)	-	D6RAC3
ENST00000511760	PIK3R4-205	680	-	-	- (aa)	-	-
ENST00000508273	PIK3R4-204	817	-	ENSP00000427302	193 (aa)	-	D6RJ98
ENST00000504834	PIK3R4-202	569	-	-	- (aa)	-	-
ENST00000512677	PIK3R4-208	744	-	-	- (aa)	-	-
ENST00000507330	PIK3R4-203	563	-	ENSP00000424274	129 (aa)	-	D6RBB7
ENST00000512362	PIK3R4-206	728	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000196455's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04136	Autophagy - other	KEGG
hsa04140	Autophagy - animal	KEGG
hsa04371	Apelin signaling pathway	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000196455	Blood Pressure	8.6922827E-006	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000196455's network

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0004672	protein kinase activity	8999962.	NAS	Function
GO:0004674	protein serine/threonine kinase activity	21873635.	IBA	Function
GO:0005515	protein binding	14617358.19270696.23878393.24785657.24849286.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005770	late endosome	21873635.	IBA	Component
GO:0005770	late endosome	14617358.	IDA	Component
GO:0005776	autophagosome	-	IEA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005930	axoneme	-	ISS	Component
GO:0006468	protein phosphorylation	21873635.	IBA	Process
GO:0006468	protein phosphorylation	8999962.	NAS	Process
GO:0006623	protein targeting to vacuole	21873635.	IBA	Process
GO:0006661	phosphatidylinositol biosynthetic process	-	TAS	Process
GO:0015630	microtubule cytoskeleton	-	IDA	Component
GO:0016020	membrane	19946888.	HDA	Component
GO:0016236	macroautophagy	21873635.	IBA	Process
GO:0016236	macroautophagy	-	TAS	Process
GO:0030242	autophagy of peroxisome	21873635.	IBA	Process
GO:0030670	phagocytic vesicle membrane	-	TAS	Component
GO:0032465	regulation of cytokinesis	20643123.	IMP	Process
GO:0032801	receptor catabolic process	20643123.	IMP	Process
GO:0034162	toll-like receptor 9 signaling pathway	-	TAS	Process
GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I	21873635.	IBA	Component
GO:0034272	phosphatidylinositol 3-kinase complex, class III, type II	21873635.	IBA	Component
GO:0035032	phosphatidylinositol 3-kinase complex, class III	-	ISS	Component
GO:0042149	cellular response to glucose starvation	-	ISS	Process
GO:0043231	intracellular membrane-bounded organelle	-	IDA	Component
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	21062745.	IDA	Process
GO:0045324	late endosome to vacuole transport	21873635.	IBA	Process
GO:0071561	nucleus-vacuole junction	21873635.	IBA	Component