EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000196588 (Gene tree)
Gene ID: 57591
Gene Symbol: MRTFA
Alias: KIAA1438|MAL|MRTF-A|BSAC|MKL|MKL1
Full Name: myocardin related transcription factor A
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 226,439 bases
Position: chr22:40,410,281-40,636,719
Accession: 14334
RBP type: canonical RBP
Summary: The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000379861	SAP	PF02037.27	1e-11	1	1
ENSP00000484786	SAP	PF02037.27	1e-11	1	1
ENSP00000385584	SAP	PF02037.27	1.3e-11	1	1
ENSP00000478420	SAP	PF02037.27	1.3e-11	1	1
ENSP00000347847	SAP	PF02037.27	1.4e-11	1	1
ENSP00000385835	SAP	PF02037.27	1.4e-11	1	1
ENSP00000479510	SAP	PF02037.27	1.5e-11	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
11431691	Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia.	Nat Genet	2001 Jul	Ma Z	-
19542301	c-Myc is a target of RNA-binding motif protein 15 in the regulation of adult hematopoietic stem cell and megakaryocyte development.	Blood	2009 Sep 3	Niu C	doi: 10.1182/blood-2009-01-197921
25585691	RNA export factor Ddx19 is required for nuclear import of the SRF coactivator MKL1.	Nat Commun	2015 Jan 14	Rajakyla EK	doi: 10.1038/ncomms6978.
20466732	Activation and repression of cellular immediate early genes by serum response factor cofactors.	J Biol Chem	2010 Jul 16	Lee SM	doi: 10.1074/jbc.M110.108878

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000466278	MRTFA-208	577	-	-	- (aa)	-	-
ENST00000407029	MRTFA-205	4091	XM_005261692	ENSP00000385835	931 (aa)	XP_005261749	Q969V6
ENST00000422851	MRTFA-206	569	-	ENSP00000398478	73 (aa)	-	B0QY74
ENST00000355630	MRTFA-201	4496	XM_005261694	ENSP00000347847	931 (aa)	XP_005261751	Q969V6
ENST00000396617	MRTFA-202	4505	-	ENSP00000379861	798 (aa)	-	E7ER32
ENST00000477468	MRTFA-209	524	-	-	- (aa)	-	-
ENST00000614754	MRTFA-210	3917	-	ENSP00000484786	799 (aa)	-	A0A087X287
ENST00000618196	MRTFA-211	2901	-	ENSP00000479510	966 (aa)	-	W0Z7M9
ENST00000463769	MRTFA-207	531	-	-	- (aa)	-	-
ENST00000402630	MRTFA-204	747	-	ENSP00000385076	161 (aa)	-	B0QY84
ENST00000620651	MRTFA-213	3757	-	ENSP00000478420	882 (aa)	-	A0A087WU73
ENST00000618417	MRTFA-212	1842	-	ENSP00000484628	85 (aa)	-	Q29R68
ENST00000402042	MRTFA-203	4343	-	ENSP00000385584	881 (aa)	-	B0QY83

Gene Model

Click here to download ENSG00000196588's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000196588	Coronary Artery Disease	6.9800000E-005	-
ENSG00000196588	Breast Neoplasms	2E-6	23535733
ENSG00000196588	Body Height	4E-6	19570815
ENSG00000196588	Mental Disorders	4E-6	20889312
ENSG00000196588	Schizophrenia	7E-10	26198764
ENSG00000196588	Breast Neoplasms	2E-6	27117709
ENSG00000196588	Breast Neoplasms	9E-19	23535729
ENSG00000196588	Breast	3E-12	27182965

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000196588	rs6001930	22	40480230	C	Breast cancer (estrogen-receptor negative)	29058716	[1.08-1.19] (Oncoarray)	1.14	EFO_1000650
ENSG00000196588	rs133047	22	40631815	T	Autism spectrum disorder or schizophrenia	28540026	[1.06-1.14]	1.1	EFO_0000692\|EFO_0003756
ENSG00000196588	rs17002034	22	40600363	?	Bipolar disorder and schizophrenia	20889312	[NR]	1.3976	EFO_0000677
ENSG00000196588	rs5995875	22	40564688	?	Breast size	27182965	[0.176-0.099] unit decrease	0.137	EFO_0004884
ENSG00000196588	rs6001930	22	40480230	?	Breast cancer	27117709	[1.01-1.14] (BRCA1 carriers)	1.07	EFO_0000305
ENSG00000196588	rs6001930	22	40480230	C	Breast cancer	23535729	[1.09-1.16]	1.12	EFO_0000305
ENSG00000196588	rs133047	22	40631815	T	Schizophrenia	26198764	[NR]	1.12	EFO_0000692
ENSG00000196588	rs6001930	22	40480230	C	Breast cancer	23535733	[1.08-1.20]	1.14	EFO_0000305
ENSG00000196588	rs5757949	22	40424147	T	Height	19570815			EFO_0004339
ENSG00000196588	rs6001930	22	40480230	C	Breast cancer	25751625	[1.09-1.16]	1.12	EFO_0000305
ENSG00000196588	rs729982	22	40414942	?	Number of common colds	28928442	[0.017-0.043] unit decrease	0.0303	EFO_0008417
ENSG00000196588	rs6001960	22	40547028	A	Coronary artery disease	29212778	[0.026-0.054] unit increase	0.04	EFO_0000378
ENSG00000196588	rs8139974	22	40432371	A	Cognitive performance	30038396	[0.011-0.022] unit increase	0.0162	EFO_0008354
ENSG00000196588	rs8139521	22	40536324	A	Self-reported math ability	30038396	[0.0082-0.0168] unit increase	0.0125	EFO_0004875
ENSG00000196588	rs17001974	22	40481380	?	Creatinine levels	29403010	[0.022-0.037] unit decrease novel	0.02934	EFO_0004518
ENSG00000196588	rs6001939	22	40496790	?	Glomerular filtration rate	29403010	[0.024-0.041] unit increase novel	0.03254	EFO_0005208
ENSG00000196588	rs9607721	22	40466116	?	Creatine kinase levels	29403010	[0.018-0.035] unit decrease novel	0.02615	EFO_0004534
ENSG00000196588	rs878756	22	40418496	T	Self-reported math ability (MTAG)	30038396	[0.0068-0.0138] unit decrease	0.0103	EFO_0004875
ENSG00000196588	rs8139974	22	40432371	A	Cognitive performance (MTAG)	30038396	[0.0099-0.0189] unit increase	0.0144	EFO_0008354
ENSG00000196588	rs10483205	22	40487595	T	Breast size	29855537	[0.095-0.21] unit decrease	0.1527	EFO_0004884
ENSG00000196588	rs17002036	22	40601107	A	Breast size	29855537	[0.097-0.212] unit decrease	0.1546	EFO_0004884
ENSG00000196588	rs76747430	22	40437838	G	Facial morphology (factor 20)	28441456	[0.1-0.26] unit decrease	0.1805	EFO_0007841
ENSG00000196588	rs729982	22	40414942	C	Uterine fibroids	30194396	[1.09-1.19]	1.14	EFO_0000731
ENSG00000196588	rs17001943	22	40466609	A	Estimated glomerular filtration rate	30604766	[0.56-1.17] ml/min/1.73m2 decrease	0.865	EFO_0005208
ENSG00000196588	rs17001977	22	40484209	?	Estimated glomerular filtration rate	30604766			EFO_0005208
ENSG00000196588	rs6001930	22	40480230	C	Breast cancer	25751625	[1.09-1.16]	1.12	EFO_0000305
ENSG00000196588	rs66987842	22	40508704	C	Breast cancer	29059683	[0.1-0.14] unit increase	0.1233	EFO_0000305
ENSG00000196588	rs6001930	22	40480230	C	Breast cancer	29059683	[1.09-1.16] (Oncoarray)	1.12	EFO_0000305
ENSG00000196588	rs6001982	22	40623944	A	Breast cancer	29059683	[0.1-0.14] unit increase	0.1207	EFO_0000305

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000196588's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000196588	MRTFA	90	84.848	ENSAPOG00000016801	mrtfba	70	52.470	Acanthochromis_polyacanthus
ENSG00000196588	MRTFA	92	98.507	ENSAPOG00000014773	mrtfab	70	52.167	Acanthochromis_polyacanthus
ENSG00000196588	MRTFA	92	77.612	ENSAPOG00000023842	mrtfbb	77	44.276	Acanthochromis_polyacanthus
ENSG00000196588	MRTFA	89	40.476	ENSAPOG00000003395	-	61	35.400	Acanthochromis_polyacanthus
ENSG00000196588	MRTFA	100	50.000	ENSAPOG00000001303	-	81	44.655	Acanthochromis_polyacanthus
ENSG00000196588	MRTFA	90	86.364	ENSAMEG00000011285	MRTFB	85	47.493	Ailuropoda_melanoleuca
ENSG00000196588	MRTFA	100	92.941	ENSAMEG00000011151	MRTFA	99	89.474	Ailuropoda_melanoleuca
ENSG00000196588	MRTFA	92	58.209	ENSAMEG00000002819	MYOCD	59	41.824	Ailuropoda_melanoleuca
ENSG00000196588	MRTFA	92	97.015	ENSACIG00000021331	mrtfab	61	88.696	Amphilophus_citrinellus
ENSG00000196588	MRTFA	92	83.582	ENSACIG00000006315	mrtfba	80	50.579	Amphilophus_citrinellus
ENSG00000196588	MRTFA	92	98.507	ENSAOCG00000004754	mrtfab	65	53.470	Amphiprion_ocellaris
ENSG00000196588	MRTFA	89	47.692	ENSAOCG00000022192	mrtfbb	73	38.487	Amphiprion_ocellaris
ENSG00000196588	MRTFA	95	48.571	ENSAOCG00000010113	-	54	37.307	Amphiprion_ocellaris
ENSG00000196588	MRTFA	92	76.119	ENSAPEG00000011634	mrtfbb	77	43.266	Amphiprion_percula
ENSG00000196588	MRTFA	92	98.507	ENSAPEG00000021018	mrtfab	66	54.041	Amphiprion_percula
ENSG00000196588	MRTFA	61	40.426	ENSAPEG00000017512	-	55	39.623	Amphiprion_percula
ENSG00000196588	MRTFA	92	98.507	ENSATEG00000007179	mrtfab	57	54.358	Anabas_testudineus
ENSG00000196588	MRTFA	90	77.273	ENSATEG00000005824	-	70	38.830	Anabas_testudineus
ENSG00000196588	MRTFA	92	77.612	ENSATEG00000004434	mrtfbb	57	43.457	Anabas_testudineus
ENSG00000196588	MRTFA	99	45.833	ENSATEG00000023953	MYOCD	57	38.658	Anabas_testudineus
ENSG00000196588	MRTFA	90	84.848	ENSATEG00000009415	mrtfba	69	52.971	Anabas_testudineus
ENSG00000196588	MRTFA	100	50.467	ENSATEG00000007239	mrtfab	60	51.376	Anabas_testudineus
ENSG00000196588	MRTFA	90	86.364	ENSAPLG00000014081	MRTFB	84	47.881	Anas_platyrhynchos
ENSG00000196588	MRTFA	92	80.597	ENSAPLG00000013526	MYOCD	55	43.814	Anas_platyrhynchos
ENSG00000196588	MRTFA	90	100.000	ENSAPLG00000014434	MRTFA	99	66.667	Anas_platyrhynchos
ENSG00000196588	MRTFA	99	36.793	ENSACAG00000017473	MYOCD	93	35.832	Anolis_carolinensis
ENSG00000196588	MRTFA	92	85.075	ENSACAG00000003638	MRTFB	93	43.310	Anolis_carolinensis
ENSG00000196588	MRTFA	100	81.176	ENSACAG00000005348	MRTFA	92	67.383	Anolis_carolinensis
ENSG00000196588	MRTFA	92	56.716	ENSANAG00000037357	MYOCD	99	35.860	Aotus_nancymaae
ENSG00000196588	MRTFA	100	97.647	ENSANAG00000035209	MRTFA	100	95.238	Aotus_nancymaae
ENSG00000196588	MRTFA	92	85.075	ENSANAG00000032247	MRTFB	77	48.973	Aotus_nancymaae
ENSG00000196588	MRTFA	92	83.582	ENSACLG00000017129	mrtfba	73	39.901	Astatotilapia_calliptera
ENSG00000196588	MRTFA	96	47.143	ENSACLG00000024360	-	55	35.816	Astatotilapia_calliptera
ENSG00000196588	MRTFA	92	98.507	ENSACLG00000018713	mrtfab	65	52.951	Astatotilapia_calliptera
ENSG00000196588	MRTFA	90	90.909	ENSACLG00000012025	-	64	44.375	Astatotilapia_calliptera
ENSG00000196588	MRTFA	89	58.462	ENSAMXG00000017729	mrtfbb	94	40.714	Astyanax_mexicanus
ENSG00000196588	MRTFA	92	79.104	ENSAMXG00000036216	MYOCD	58	44.498	Astyanax_mexicanus
ENSG00000196588	MRTFA	92	98.507	ENSAMXG00000007612	mrtfab	78	53.945	Astyanax_mexicanus
ENSG00000196588	MRTFA	92	85.075	ENSBTAG00000008728	MRTFB	75	53.061	Bos_taurus
ENSG00000196588	MRTFA	100	94.118	ENSBTAG00000002630	MRTFA	100	79.291	Bos_taurus
ENSG00000196588	MRTFA	92	62.687	ENSBTAG00000035706	MYOCD	62	44.150	Bos_taurus
ENSG00000196588	MRTFA	92	85.075	ENSCJAG00000015925	MRTFB	97	42.447	Callithrix_jacchus
ENSG00000196588	MRTFA	92	56.716	ENSCJAG00000004683	MYOCD	99	36.292	Callithrix_jacchus
ENSG00000196588	MRTFA	100	96.471	ENSCJAG00000002850	MRTFA	100	94.899	Callithrix_jacchus
ENSG00000196588	MRTFA	92	61.194	ENSCAFG00000017863	MYOCD	97	37.903	Canis_familiaris
ENSG00000196588	MRTFA	100	94.118	ENSCAFG00000001154	MRTFA	100	89.328	Canis_familiaris
ENSG00000196588	MRTFA	92	85.075	ENSCAFG00000018810	MRTFB	84	47.398	Canis_familiaris
ENSG00000196588	MRTFA	100	94.118	ENSCAFG00020002129	MRTFA	100	89.328	Canis_lupus_dingo
ENSG00000196588	MRTFA	92	85.075	ENSCAFG00020024137	MRTFB	81	48.373	Canis_lupus_dingo
ENSG00000196588	MRTFA	97	38.156	ENSCAFG00020001034	MYOCD	97	37.513	Canis_lupus_dingo
ENSG00000196588	MRTFA	92	62.687	ENSCHIG00000021206	MYOCD	62	44.150	Capra_hircus
ENSG00000196588	MRTFA	100	94.118	ENSCHIG00000016119	MRTFA	99	84.995	Capra_hircus
ENSG00000196588	MRTFA	92	85.075	ENSCHIG00000018957	MRTFB	75	52.551	Capra_hircus
ENSG00000196588	MRTFA	100	95.294	ENSTSYG00000007397	MRTFA	100	92.962	Carlito_syrichta
ENSG00000196588	MRTFA	92	62.687	ENSTSYG00000014685	MYOCD	74	44.150	Carlito_syrichta
ENSG00000196588	MRTFA	97	81.690	ENSTSYG00000005893	MRTFB	77	49.531	Carlito_syrichta
ENSG00000196588	MRTFA	92	56.716	ENSCAPG00000007773	MYOCD	99	36.139	Cavia_aperea
ENSG00000196588	MRTFA	96	50.000	ENSCAPG00000014472	MRTFB	81	77.143	Cavia_aperea
ENSG00000196588	MRTFA	90	86.364	ENSCPOG00000010356	MRTFB	80	48.673	Cavia_porcellus
ENSG00000196588	MRTFA	92	56.716	ENSCPOG00000002421	MYOCD	99	36.238	Cavia_porcellus
ENSG00000196588	MRTFA	100	91.765	ENSCPOG00000009883	MRTFA	94	87.302	Cavia_porcellus
ENSG00000196588	MRTFA	92	55.224	ENSCCAG00000035642	MYOCD	99	34.981	Cebus_capucinus
ENSG00000196588	MRTFA	92	85.075	ENSCCAG00000036874	MRTFB	77	49.605	Cebus_capucinus
ENSG00000196588	MRTFA	100	97.647	ENSCCAG00000027355	MRTFA	100	94.867	Cebus_capucinus
ENSG00000196588	MRTFA	92	85.075	ENSCATG00000039198	MRTFB	95	41.802	Cercocebus_atys
ENSG00000196588	MRTFA	100	98.824	ENSCATG00000044298	MRTFA	100	96.614	Cercocebus_atys
ENSG00000196588	MRTFA	99	33.234	ENSCATG00000031443	MYOCD	94	64.634	Cercocebus_atys
ENSG00000196588	MRTFA	92	59.701	ENSCLAG00000009669	MYOCD	99	36.715	Chinchilla_lanigera
ENSG00000196588	MRTFA	100	91.765	ENSCLAG00000016828	MRTFA	90	87.227	Chinchilla_lanigera
ENSG00000196588	MRTFA	92	85.075	ENSCLAG00000012268	MRTFB	78	49.377	Chinchilla_lanigera
ENSG00000196588	MRTFA	90	86.364	ENSCSAG00000008148	MRTFB	80	50.238	Chlorocebus_sabaeus
ENSG00000196588	MRTFA	100	98.824	ENSCSAG00000005969	MRTFA	100	96.684	Chlorocebus_sabaeus
ENSG00000196588	MRTFA	92	58.209	ENSCSAG00000009104	MYOCD	59	41.900	Chlorocebus_sabaeus
ENSG00000196588	MRTFA	92	43.284	ENSCHOG00000003374	MYOCD	70	40.946	Choloepus_hoffmanni
ENSG00000196588	MRTFA	54	100.000	ENSCHOG00000006407	-	79	100.000	Choloepus_hoffmanni
ENSG00000196588	MRTFA	78	75.796	ENSCHOG00000003309	MRTFB	74	46.523	Choloepus_hoffmanni
ENSG00000196588	MRTFA	92	79.104	ENSCPBG00000027766	MYOCD	99	39.034	Chrysemys_picta_bellii
ENSG00000196588	MRTFA	92	98.507	ENSCPBG00000022902	MRTFA	89	73.217	Chrysemys_picta_bellii
ENSG00000196588	MRTFA	92	86.567	ENSCPBG00000006634	MRTFB	84	48.476	Chrysemys_picta_bellii
ENSG00000196588	MRTFA	92	85.075	ENSCANG00000001876	MRTFB	77	49.921	Colobus_angolensis_palliatus
ENSG00000196588	MRTFA	92	58.209	ENSCANG00000037094	MYOCD	99	43.227	Colobus_angolensis_palliatus
ENSG00000196588	MRTFA	100	98.824	ENSCANG00000035624	MRTFA	100	96.392	Colobus_angolensis_palliatus
ENSG00000196588	MRTFA	92	85.075	ENSCGRG00001010790	Mkl2	86	46.438	Cricetulus_griseus_chok1gshd
ENSG00000196588	MRTFA	100	94.118	ENSCGRG00001018160	Mkl1	100	85.102	Cricetulus_griseus_chok1gshd
ENSG00000196588	MRTFA	100	57.534	ENSCGRG00001007362	Myocd	99	36.816	Cricetulus_griseus_chok1gshd
ENSG00000196588	MRTFA	100	94.118	ENSCGRG00000016476	Mkl1	100	85.102	Cricetulus_griseus_crigri
ENSG00000196588	MRTFA	89	60.000	ENSCGRG00000008047	Myocd	82	42.857	Cricetulus_griseus_crigri
ENSG00000196588	MRTFA	92	85.075	ENSCGRG00000016496	Mkl2	86	46.438	Cricetulus_griseus_crigri
ENSG00000196588	MRTFA	63	73.913	ENSCSEG00000010386	mrtfbb	79	39.543	Cynoglossus_semilaevis
ENSG00000196588	MRTFA	92	97.015	ENSCSEG00000020403	mrtfab	58	50.926	Cynoglossus_semilaevis
ENSG00000196588	MRTFA	90	84.848	ENSCSEG00000019654	mrtfba	69	49.831	Cynoglossus_semilaevis
ENSG00000196588	MRTFA	92	83.582	ENSCVAG00000006215	mrtfba	70	51.107	Cyprinodon_variegatus
ENSG00000196588	MRTFA	89	31.338	ENSCVAG00000002376	MYOCD	80	32.570	Cyprinodon_variegatus
ENSG00000196588	MRTFA	92	74.627	ENSCVAG00000015781	mrtfbb	81	43.360	Cyprinodon_variegatus
ENSG00000196588	MRTFA	92	98.507	ENSCVAG00000002168	mrtfab	77	53.440	Cyprinodon_variegatus
ENSG00000196588	MRTFA	90	69.697	ENSCVAG00000003195	-	79	39.206	Cyprinodon_variegatus
ENSG00000196588	MRTFA	97	89.189	ENSDARG00000075867	mrtfaa	67	52.295	Danio_rerio
ENSG00000196588	MRTFA	97	92.958	ENSDARG00000076229	mrtfab	65	53.595	Danio_rerio
ENSG00000196588	MRTFA	97	77.465	ENSDARG00000076867	mrtfbb	55	47.395	Danio_rerio
ENSG00000196588	MRTFA	92	85.075	ENSDARG00000088307	mrtfba	73	53.002	Danio_rerio
ENSG00000196588	MRTFA	92	98.507	ENSDNOG00000038468	MRTFA	98	84.242	Dasypus_novemcinctus
ENSG00000196588	MRTFA	92	65.672	ENSDNOG00000035642	MYOCD	81	44.343	Dasypus_novemcinctus
ENSG00000196588	MRTFA	90	86.364	ENSDNOG00000001899	MRTFB	78	51.024	Dasypus_novemcinctus
ENSG00000196588	MRTFA	100	92.941	ENSDORG00000000727	Mkl1	99	82.821	Dipodomys_ordii
ENSG00000196588	MRTFA	92	59.701	ENSDORG00000028541	Myocd	86	39.847	Dipodomys_ordii
ENSG00000196588	MRTFA	92	85.075	ENSDORG00000004843	Mkl2	84	47.868	Dipodomys_ordii
ENSG00000196588	MRTFA	90	83.333	ENSETEG00000008792	MRTFB	62	51.706	Echinops_telfairi
ENSG00000196588	MRTFA	100	89.412	ENSETEG00000006697	MRTFA	84	76.555	Echinops_telfairi
ENSG00000196588	MRTFA	97	85.915	ENSEBUG00000010120	MYOCD	64	72.727	Eptatretus_burgeri
ENSG00000196588	MRTFA	100	94.118	ENSEASG00005002011	MRTFA	99	90.498	Equus_asinus_asinus
ENSG00000196588	MRTFA	90	62.121	ENSEASG00005016841	MYOCD	97	36.510	Equus_asinus_asinus
ENSG00000196588	MRTFA	93	85.294	ENSEASG00005011411	MRTFB	83	47.100	Equus_asinus_asinus
ENSG00000196588	MRTFA	100	94.118	ENSECAG00000013950	MRTFA	100	85.597	Equus_caballus
ENSG00000196588	MRTFA	92	85.075	ENSECAG00000002400	MRTFB	83	46.893	Equus_caballus
ENSG00000196588	MRTFA	92	59.701	ENSECAG00000025166	MYOCD	59	42.130	Equus_caballus
ENSG00000196588	MRTFA	90	86.364	ENSEEUG00000001036	MRTFB	86	45.856	Erinaceus_europaeus
ENSG00000196588	MRTFA	100	91.765	ENSEEUG00000007515	MRTFA	82	76.944	Erinaceus_europaeus
ENSG00000196588	MRTFA	100	56.044	ENSELUG00000007233	mrtfaa	85	53.547	Esox_lucius
ENSG00000196588	MRTFA	90	87.879	ENSELUG00000019087	mrtfba	66	50.508	Esox_lucius
ENSG00000196588	MRTFA	97	80.282	ENSELUG00000021530	mrtfbb	81	47.434	Esox_lucius
ENSG00000196588	MRTFA	89	43.077	ENSELUG00000022024	MYOCD	52	40.263	Esox_lucius
ENSG00000196588	MRTFA	100	92.941	ENSFCAG00000004802	MRTFA	100	88.017	Felis_catus
ENSG00000196588	MRTFA	92	85.075	ENSFCAG00000030482	MRTFB	86	47.154	Felis_catus
ENSG00000196588	MRTFA	92	59.701	ENSFCAG00000011071	MYOCD	99	38.345	Felis_catus
ENSG00000196588	MRTFA	90	98.485	ENSFALG00000012129	MRTFA	99	69.960	Ficedula_albicollis
ENSG00000196588	MRTFA	90	86.364	ENSFALG00000003904	MRTFB	83	47.383	Ficedula_albicollis
ENSG00000196588	MRTFA	92	82.090	ENSFALG00000011169	MYOCD	99	35.721	Ficedula_albicollis
ENSG00000196588	MRTFA	92	85.075	ENSFDAG00000009819	MRTFB	84	46.399	Fukomys_damarensis
ENSG00000196588	MRTFA	92	59.701	ENSFDAG00000010479	MYOCD	62	42.254	Fukomys_damarensis
ENSG00000196588	MRTFA	100	91.765	ENSFDAG00000006435	MRTFA	100	83.196	Fukomys_damarensis
ENSG00000196588	MRTFA	92	76.119	ENSFHEG00000002738	mrtfbb	97	37.808	Fundulus_heteroclitus
ENSG00000196588	MRTFA	92	97.015	ENSFHEG00000016878	mrtfab	58	77.778	Fundulus_heteroclitus
ENSG00000196588	MRTFA	90	52.747	ENSFHEG00000005266	-	63	46.400	Fundulus_heteroclitus
ENSG00000196588	MRTFA	92	85.075	ENSGMOG00000000632	mrtfba	67	61.130	Gadus_morhua
ENSG00000196588	MRTFA	91	43.902	ENSGMOG00000017784	-	90	51.613	Gadus_morhua
ENSG00000196588	MRTFA	90	77.273	ENSGMOG00000004360	mrtfbb	61	80.357	Gadus_morhua
ENSG00000196588	MRTFA	59	100.000	ENSGMOG00000017330	mrtfab	64	54.902	Gadus_morhua
ENSG00000196588	MRTFA	92	98.507	ENSGALG00000012024	MRTFA	63	72.568	Gallus_gallus
ENSG00000196588	MRTFA	96	53.659	ENSGALG00000003026	-	100	39.007	Gallus_gallus
ENSG00000196588	MRTFA	99	79.167	ENSGALG00000001021	MYOCD	87	44.496	Gallus_gallus
ENSG00000196588	MRTFA	90	100.000	ENSGAFG00000008113	mrtfab	51	53.514	Gambusia_affinis
ENSG00000196588	MRTFA	76	57.447	ENSGAFG00000010084	-	50	57.447	Gambusia_affinis
ENSG00000196588	MRTFA	92	83.582	ENSGAFG00000002886	mrtfba	54	52.381	Gambusia_affinis
ENSG00000196588	MRTFA	92	73.134	ENSGAFG00000017947	mrtfbb	81	43.937	Gambusia_affinis
ENSG00000196588	MRTFA	92	89.552	ENSGACG00000008394	-	100	42.570	Gasterosteus_aculeatus
ENSG00000196588	MRTFA	90	80.303	ENSGACG00000013988	mrtfbb	74	44.182	Gasterosteus_aculeatus
ENSG00000196588	MRTFA	90	83.333	ENSGACG00000004442	mrtfba	72	49.085	Gasterosteus_aculeatus
ENSG00000196588	MRTFA	90	100.000	ENSGACG00000005014	mrtfab	99	45.672	Gasterosteus_aculeatus
ENSG00000196588	MRTFA	85	32.586	ENSGACG00000002295	MYOCD	82	36.667	Gasterosteus_aculeatus
ENSG00000196588	MRTFA	92	98.507	ENSGAGG00000009658	MRTFA	90	72.886	Gopherus_agassizii
ENSG00000196588	MRTFA	92	79.104	ENSGAGG00000022912	MYOCD	99	39.802	Gopherus_agassizii
ENSG00000196588	MRTFA	61	88.776	ENSGAGG00000001965	MRTFB	99	44.467	Gopherus_agassizii
ENSG00000196588	MRTFA	92	58.209	ENSGGOG00000008879	MYOCD	62	41.589	Gorilla_gorilla
ENSG00000196588	MRTFA	100	100.000	ENSGGOG00000015180	MKL1	100	98.965	Gorilla_gorilla
ENSG00000196588	MRTFA	92	85.075	ENSGGOG00000008762	MKL2	77	49.684	Gorilla_gorilla
ENSG00000196588	MRTFA	90	92.424	ENSHBUG00000013729	-	65	44.704	Haplochromis_burtoni
ENSG00000196588	MRTFA	65	38.783	ENSHBUG00000006978	MYOCD	57	40.741	Haplochromis_burtoni
ENSG00000196588	MRTFA	92	83.582	ENSHBUG00000016214	mrtfba	70	52.405	Haplochromis_burtoni
ENSG00000196588	MRTFA	92	98.507	ENSHBUG00000023207	mrtfab	65	52.119	Haplochromis_burtoni
ENSG00000196588	MRTFA	100	92.941	ENSHGLG00000009723	MRTFA	100	84.886	Heterocephalus_glaber_female
ENSG00000196588	MRTFA	92	85.075	ENSHGLG00000019009	MRTFB	84	46.750	Heterocephalus_glaber_female
ENSG00000196588	MRTFA	67	31.969	ENSHGLG00000003653	MYOCD	69	30.721	Heterocephalus_glaber_female
ENSG00000196588	MRTFA	100	92.941	ENSHGLG00100016746	MRTFA	100	84.385	Heterocephalus_glaber_male
ENSG00000196588	MRTFA	92	85.075	ENSHGLG00100013738	MRTFB	84	46.750	Heterocephalus_glaber_male
ENSG00000196588	MRTFA	92	98.507	ENSHCOG00000009798	mrtfab	86	49.302	Hippocampus_comes
ENSG00000196588	MRTFA	93	85.294	ENSIPUG00000001798	mkl2	84	48.567	Ictalurus_punctatus
ENSG00000196588	MRTFA	92	82.090	ENSIPUG00000019606	mrtfbb	56	49.916	Ictalurus_punctatus
ENSG00000196588	MRTFA	96	77.143	ENSIPUG00000005012	myocd	70	39.055	Ictalurus_punctatus
ENSG00000196588	MRTFA	92	95.522	ENSIPUG00000000739	mrtfab	71	53.202	Ictalurus_punctatus
ENSG00000196588	MRTFA	92	61.194	ENSSTOG00000011741	MYOCD	83	40.336	Ictidomys_tridecemlineatus
ENSG00000196588	MRTFA	92	85.075	ENSSTOG00000013006	MRTFB	74	51.959	Ictidomys_tridecemlineatus
ENSG00000196588	MRTFA	100	94.118	ENSSTOG00000002947	MRTFA	100	88.716	Ictidomys_tridecemlineatus
ENSG00000196588	MRTFA	92	85.075	ENSJJAG00000023088	Mkl2	83	46.077	Jaculus_jaculus
ENSG00000196588	MRTFA	92	58.209	ENSJJAG00000013377	Myocd	75	41.385	Jaculus_jaculus
ENSG00000196588	MRTFA	99	82.963	ENSJJAG00000019590	Mkl1	99	82.099	Jaculus_jaculus
ENSG00000196588	MRTFA	92	74.627	ENSKMAG00000018740	mrtfbb	78	43.493	Kryptolebias_marmoratus
ENSG00000196588	MRTFA	88	82.812	ENSKMAG00000016870	-	65	45.736	Kryptolebias_marmoratus
ENSG00000196588	MRTFA	92	83.582	ENSKMAG00000021834	mrtfba	72	52.659	Kryptolebias_marmoratus
ENSG00000196588	MRTFA	92	97.015	ENSKMAG00000002014	mrtfab	75	52.258	Kryptolebias_marmoratus
ENSG00000196588	MRTFA	79	79.310	ENSLBEG00000023994	mrtfbb	59	44.312	Labrus_bergylta
ENSG00000196588	MRTFA	92	97.015	ENSLBEG00000002808	mrtfab	66	51.800	Labrus_bergylta
ENSG00000196588	MRTFA	90	84.848	ENSLBEG00000025364	mrtfba	74	49.683	Labrus_bergylta
ENSG00000196588	MRTFA	70	35.304	ENSLBEG00000027845	-	58	37.973	Labrus_bergylta
ENSG00000196588	MRTFA	92	86.567	ENSLACG00000010786	MRTFB	81	44.595	Latimeria_chalumnae
ENSG00000196588	MRTFA	64	76.596	ENSLACG00000014027	MYOCD	87	42.388	Latimeria_chalumnae
ENSG00000196588	MRTFA	100	59.794	ENSLACG00000005378	MRTFA	87	53.305	Latimeria_chalumnae
ENSG00000196588	MRTFA	86	38.415	ENSLOCG00000012138	MYOCD	81	38.275	Lepisosteus_oculatus
ENSG00000196588	MRTFA	92	86.567	ENSLOCG00000007529	mrtfbb	52	89.552	Lepisosteus_oculatus
ENSG00000196588	MRTFA	90	86.364	ENSLAFG00000000366	MRTFB	83	45.760	Loxodonta_africana
ENSG00000196588	MRTFA	97	59.155	ENSLAFG00000012269	MYOCD	61	43.910	Loxodonta_africana
ENSG00000196588	MRTFA	100	89.412	ENSLAFG00000030989	MRTFA	99	80.430	Loxodonta_africana
ENSG00000196588	MRTFA	99	36.810	ENSMFAG00000036055	MYOCD	98	35.444	Macaca_fascicularis
ENSG00000196588	MRTFA	100	98.824	ENSMFAG00000046410	MRTFA	100	96.953	Macaca_fascicularis
ENSG00000196588	MRTFA	92	85.075	ENSMFAG00000003274	MRTFB	95	41.802	Macaca_fascicularis
ENSG00000196588	MRTFA	92	85.075	ENSMMUG00000017379	MRTFB	95	41.802	Macaca_mulatta
ENSG00000196588	MRTFA	92	58.209	ENSMMUG00000013281	MYOCD	99	36.499	Macaca_mulatta
ENSG00000196588	MRTFA	100	98.824	ENSMMUG00000020411	MRTFA	100	96.840	Macaca_mulatta
ENSG00000196588	MRTFA	100	98.824	ENSMNEG00000031219	MRTFA	100	96.953	Macaca_nemestrina
ENSG00000196588	MRTFA	92	58.209	ENSMNEG00000045528	MYOCD	71	42.056	Macaca_nemestrina
ENSG00000196588	MRTFA	92	85.075	ENSMNEG00000039623	MRTFB	78	49.764	Macaca_nemestrina
ENSG00000196588	MRTFA	100	98.824	ENSMLEG00000036191	MRTFA	100	96.727	Mandrillus_leucophaeus
ENSG00000196588	MRTFA	99	35.743	ENSMLEG00000003454	MYOCD	59	41.363	Mandrillus_leucophaeus
ENSG00000196588	MRTFA	92	85.075	ENSMLEG00000039557	MRTFB	95	41.707	Mandrillus_leucophaeus
ENSG00000196588	MRTFA	97	88.732	ENSMAMG00000005317	-	56	50.820	Mastacembelus_armatus
ENSG00000196588	MRTFA	90	84.848	ENSMAMG00000004563	mrtfba	72	52.534	Mastacembelus_armatus
ENSG00000196588	MRTFA	92	77.612	ENSMAMG00000002859	mrtfbb	77	45.561	Mastacembelus_armatus
ENSG00000196588	MRTFA	92	97.015	ENSMAMG00000003242	mrtfab	73	54.517	Mastacembelus_armatus
ENSG00000196588	MRTFA	90	46.970	ENSMZEG00005003907	MYOCD	55	35.816	Maylandia_zebra
ENSG00000196588	MRTFA	92	83.582	ENSMZEG00005007344	mrtfba	70	52.234	Maylandia_zebra
ENSG00000196588	MRTFA	92	98.507	ENSMZEG00005028077	mrtfab	65	52.119	Maylandia_zebra
ENSG00000196588	MRTFA	90	90.909	ENSMZEG00005006274	-	65	43.486	Maylandia_zebra
ENSG00000196588	MRTFA	96	82.927	ENSMGAG00000012307	MRTFA	88	72.404	Meleagris_gallopavo
ENSG00000196588	MRTFA	90	86.364	ENSMGAG00000000972	MRTFB	83	48.645	Meleagris_gallopavo
ENSG00000196588	MRTFA	92	82.090	ENSMGAG00000002098	MYOCD	99	35.571	Meleagris_gallopavo
ENSG00000196588	MRTFA	92	85.075	ENSMAUG00000008606	Mkl2	79	46.719	Mesocricetus_auratus
ENSG00000196588	MRTFA	99	82.080	ENSMAUG00000012578	Mkl1	99	81.830	Mesocricetus_auratus
ENSG00000196588	MRTFA	100	54.795	ENSMAUG00000020107	Myocd	99	36.563	Mesocricetus_auratus
ENSG00000196588	MRTFA	92	61.194	ENSMICG00000002408	MYOCD	99	37.476	Microcebus_murinus
ENSG00000196588	MRTFA	92	85.075	ENSMICG00000007900	MRTFB	81	49.183	Microcebus_murinus
ENSG00000196588	MRTFA	100	96.471	ENSMICG00000005671	MRTFA	100	92.680	Microcebus_murinus
ENSG00000196588	MRTFA	100	94.118	ENSMOCG00000021144	Mkl1	100	85.407	Microtus_ochrogaster
ENSG00000196588	MRTFA	92	85.075	ENSMOCG00000022536	Mkl2	75	51.256	Microtus_ochrogaster
ENSG00000196588	MRTFA	100	58.904	ENSMOCG00000021190	Myocd	99	36.000	Microtus_ochrogaster
ENSG00000196588	MRTFA	92	76.119	ENSMMOG00000014836	mrtfbb	100	38.061	Mola_mola
ENSG00000196588	MRTFA	92	83.582	ENSMMOG00000003501	mrtfba	54	51.525	Mola_mola
ENSG00000196588	MRTFA	83	60.530	ENSMODG00000012937	-	100	60.699	Monodelphis_domestica
ENSG00000196588	MRTFA	59	46.512	ENSMODG00000008185	MYOCD	55	34.759	Monodelphis_domestica
ENSG00000196588	MRTFA	90	86.364	ENSMODG00000004880	MRTFB	81	48.571	Monodelphis_domestica
ENSG00000196588	MRTFA	76	42.035	ENSMALG00000020799	mrtfbb	76	42.218	Monopterus_albus
ENSG00000196588	MRTFA	94	34.146	ENSMALG00000008731	MYOCD	73	37.402	Monopterus_albus
ENSG00000196588	MRTFA	92	98.507	ENSMALG00000009693	mrtfab	58	53.259	Monopterus_albus
ENSG00000196588	MRTFA	92	82.090	ENSMALG00000009662	mrtfba	69	51.433	Monopterus_albus
ENSG00000196588	MRTFA	100	56.164	MGP_CAROLIEiJ_G0016512	Myocd	99	35.650	Mus_caroli
ENSG00000196588	MRTFA	100	92.941	MGP_CAROLIEiJ_G0020047	Mkl1	100	84.346	Mus_caroli
ENSG00000196588	MRTFA	92	85.075	MGP_CAROLIEiJ_G0020465	Mkl2	85	47.260	Mus_caroli
ENSG00000196588	MRTFA	92	85.075	ENSMUSG00000009569	Mkl2	85	47.548	Mus_musculus
ENSG00000196588	MRTFA	100	92.941	ENSMUSG00000042292	Mkl1	100	83.934	Mus_musculus
ENSG00000196588	MRTFA	100	56.164	ENSMUSG00000020542	Myocd	95	35.632	Mus_musculus
ENSG00000196588	MRTFA	92	85.075	MGP_PahariEiJ_G0016171	Mkl2	86	46.594	Mus_pahari
ENSG00000196588	MRTFA	100	92.941	MGP_PahariEiJ_G0020049	Mkl1	100	84.758	Mus_pahari
ENSG00000196588	MRTFA	100	56.164	MGP_PahariEiJ_G0017641	Myocd	99	35.516	Mus_pahari
ENSG00000196588	MRTFA	92	85.075	MGP_SPRETEiJ_G0021360	Mkl2	85	47.139	Mus_spretus
ENSG00000196588	MRTFA	100	92.941	MGP_SPRETEiJ_G0020945	Mkl1	100	83.728	Mus_spretus
ENSG00000196588	MRTFA	100	54.795	MGP_SPRETEiJ_G0017349	Myocd	99	35.941	Mus_spretus
ENSG00000196588	MRTFA	92	85.075	ENSMPUG00000014475	MRTFB	83	49.231	Mustela_putorius_furo
ENSG00000196588	MRTFA	92	61.194	ENSMPUG00000003656	MYOCD	59	43.818	Mustela_putorius_furo
ENSG00000196588	MRTFA	100	92.941	ENSMPUG00000016438	MRTFA	87	86.743	Mustela_putorius_furo
ENSG00000196588	MRTFA	90	86.364	ENSMLUG00000000799	MRTFB	86	46.806	Myotis_lucifugus
ENSG00000196588	MRTFA	93	57.353	ENSMLUG00000015006	MYOCD	58	44.745	Myotis_lucifugus
ENSG00000196588	MRTFA	100	95.294	ENSMLUG00000005421	MRTFA	99	88.486	Myotis_lucifugus
ENSG00000196588	MRTFA	92	85.075	ENSNGAG00000023146	Mkl2	84	46.797	Nannospalax_galili
ENSG00000196588	MRTFA	99	84.829	ENSNGAG00000019442	Mkl1	99	84.450	Nannospalax_galili
ENSG00000196588	MRTFA	100	56.164	ENSNGAG00000019776	Myocd	99	36.117	Nannospalax_galili
ENSG00000196588	MRTFA	92	98.507	ENSNBRG00000004360	mrtfab	65	52.960	Neolamprologus_brichardi
ENSG00000196588	MRTFA	65	37.944	ENSNBRG00000012337	-	58	37.871	Neolamprologus_brichardi
ENSG00000196588	MRTFA	71	78.846	ENSNBRG00000005688	-	78	50.000	Neolamprologus_brichardi
ENSG00000196588	MRTFA	92	83.582	ENSNBRG00000017588	mrtfba	53	53.093	Neolamprologus_brichardi
ENSG00000196588	MRTFA	92	58.209	ENSNLEG00000014576	MYOCD	62	41.433	Nomascus_leucogenys
ENSG00000196588	MRTFA	92	85.075	ENSNLEG00000010224	MRTFB	95	43.359	Nomascus_leucogenys
ENSG00000196588	MRTFA	92	98.507	ENSNLEG00000015359	MRTFA	100	92.102	Nomascus_leucogenys
ENSG00000196588	MRTFA	60	56.250	ENSMEUG00000009501	MYOCD	57	49.550	Notamacropus_eugenii
ENSG00000196588	MRTFA	82	86.047	ENSMEUG00000008459	MRTFB	75	86.047	Notamacropus_eugenii
ENSG00000196588	MRTFA	100	82.353	ENSMEUG00000001042	MRTFA	100	70.331	Notamacropus_eugenii
ENSG00000196588	MRTFA	100	85.882	ENSOPRG00000012126	MRTFA	89	79.327	Ochotona_princeps
ENSG00000196588	MRTFA	90	86.364	ENSOPRG00000015220	-	63	89.000	Ochotona_princeps
ENSG00000196588	MRTFA	99	79.849	ENSODEG00000012960	MRTFA	99	79.849	Octodon_degus
ENSG00000196588	MRTFA	92	85.075	ENSODEG00000002623	MRTFB	85	46.722	Octodon_degus
ENSG00000196588	MRTFA	92	59.701	ENSODEG00000000852	MYOCD	99	35.905	Octodon_degus
ENSG00000196588	MRTFA	92	40.299	ENSONIG00000019532	MYOCD	57	39.573	Oreochromis_niloticus
ENSG00000196588	MRTFA	90	92.424	ENSONIG00000007040	-	75	47.635	Oreochromis_niloticus
ENSG00000196588	MRTFA	92	83.582	ENSONIG00000019764	mrtfba	74	52.668	Oreochromis_niloticus
ENSG00000196588	MRTFA	90	78.788	ENSONIG00000001419	mrtfbb	76	45.946	Oreochromis_niloticus
ENSG00000196588	MRTFA	90	100.000	ENSONIG00000019711	mrtfab	99	48.307	Oreochromis_niloticus
ENSG00000196588	MRTFA	63	40.820	ENSOANG00000003001	-	69	38.086	Ornithorhynchus_anatinus
ENSG00000196588	MRTFA	92	85.075	ENSOANG00000007151	MRTFB	83	49.164	Ornithorhynchus_anatinus
ENSG00000196588	MRTFA	100	58.904	ENSOCUG00000009225	MYOCD	59	41.857	Oryctolagus_cuniculus
ENSG00000196588	MRTFA	93	85.294	ENSOCUG00000015855	MRTFB	77	48.607	Oryctolagus_cuniculus
ENSG00000196588	MRTFA	100	92.941	ENSOCUG00000023730	MRTFA	80	95.597	Oryctolagus_cuniculus
ENSG00000196588	MRTFA	100	76.712	ENSORLG00000002977	mrtfba	72	52.911	Oryzias_latipes
ENSG00000196588	MRTFA	92	98.507	ENSORLG00000002421	mrtfab	70	54.058	Oryzias_latipes
ENSG00000196588	MRTFA	63	34.572	ENSORLG00000013047	MYOCD	59	33.333	Oryzias_latipes
ENSG00000196588	MRTFA	92	79.104	ENSORLG00000005094	mrtfbb	64	41.843	Oryzias_latipes
ENSG00000196588	MRTFA	90	72.727	ENSORLG00000013273	-	70	40.394	Oryzias_latipes
ENSG00000196588	MRTFA	92	79.104	ENSORLG00020005282	mrtfbb	64	41.843	Oryzias_latipes_hni
ENSG00000196588	MRTFA	92	98.507	ENSORLG00020007944	mrtfab	66	53.612	Oryzias_latipes_hni
ENSG00000196588	MRTFA	62	34.962	ENSORLG00020020263	-	50	33.694	Oryzias_latipes_hni
ENSG00000196588	MRTFA	100	76.712	ENSORLG00020006434	mrtfba	72	53.002	Oryzias_latipes_hni
ENSG00000196588	MRTFA	90	72.727	ENSORLG00020009919	-	70	40.099	Oryzias_latipes_hni
ENSG00000196588	MRTFA	92	82.090	ENSORLG00015005233	mrtfba	57	52.830	Oryzias_latipes_hsok
ENSG00000196588	MRTFA	90	72.727	ENSORLG00015020937	-	70	39.604	Oryzias_latipes_hsok
ENSG00000196588	MRTFA	63	34.381	ENSORLG00015019094	MYOCD	64	35.258	Oryzias_latipes_hsok
ENSG00000196588	MRTFA	92	98.507	ENSORLG00015006492	mrtfab	65	52.978	Oryzias_latipes_hsok
ENSG00000196588	MRTFA	90	71.212	ENSOMEG00000022122	-	69	45.128	Oryzias_melastigma
ENSG00000196588	MRTFA	51	32.422	ENSOMEG00000022092	MYOCD	61	34.639	Oryzias_melastigma
ENSG00000196588	MRTFA	92	97.015	ENSOMEG00000009541	mrtfab	69	54.207	Oryzias_melastigma
ENSG00000196588	MRTFA	90	80.303	ENSOMEG00000023982	mrtfbb	87	42.290	Oryzias_melastigma
ENSG00000196588	MRTFA	92	83.582	ENSOMEG00000007794	mrtfba	69	53.859	Oryzias_melastigma
ENSG00000196588	MRTFA	90	86.364	ENSOGAG00000014617	MRTFB	72	52.115	Otolemur_garnettii
ENSG00000196588	MRTFA	100	94.118	ENSOGAG00000003217	MRTFA	100	88.854	Otolemur_garnettii
ENSG00000196588	MRTFA	90	59.091	ENSOGAG00000004448	MYOCD	99	35.915	Otolemur_garnettii
ENSG00000196588	MRTFA	93	61.765	ENSOARG00000015496	MYOCD	58	44.268	Ovis_aries
ENSG00000196588	MRTFA	96	93.902	ENSOARG00000017567	MRTFA	89	70.145	Ovis_aries
ENSG00000196588	MRTFA	90	86.364	ENSOARG00000007471	MRTFB	77	52.034	Ovis_aries
ENSG00000196588	MRTFA	92	56.716	ENSPPAG00000040890	MYOCD	62	41.433	Pan_paniscus
ENSG00000196588	MRTFA	100	100.000	ENSPPAG00000020762	MRTFA	100	95.756	Pan_paniscus
ENSG00000196588	MRTFA	92	85.075	ENSPPAG00000040279	MRTFB	77	49.842	Pan_paniscus
ENSG00000196588	MRTFA	92	85.075	ENSPPRG00000024730	MRTFB	85	47.684	Panthera_pardus
ENSG00000196588	MRTFA	100	92.941	ENSPPRG00000013444	MRTFA	100	88.751	Panthera_pardus
ENSG00000196588	MRTFA	92	59.701	ENSPPRG00000013106	MYOCD	99	38.345	Panthera_pardus
ENSG00000196588	MRTFA	92	85.075	ENSPTIG00000014959	MRTFB	76	53.559	Panthera_tigris_altaica
ENSG00000196588	MRTFA	100	92.941	ENSPTIG00000010561	MRTFA	99	83.864	Panthera_tigris_altaica
ENSG00000196588	MRTFA	92	58.209	ENSPTRG00000008786	MYOCD	62	41.589	Pan_troglodytes
ENSG00000196588	MRTFA	100	100.000	ENSPTRG00000014409	MRTFA	100	99.093	Pan_troglodytes
ENSG00000196588	MRTFA	92	85.075	ENSPTRG00000007791	MRTFB	77	49.842	Pan_troglodytes
ENSG00000196588	MRTFA	92	85.075	ENSPANG00000020098	MRTFB	95	42.095	Papio_anubis
ENSG00000196588	MRTFA	100	98.824	ENSPANG00000024733	MRTFA	100	96.953	Papio_anubis
ENSG00000196588	MRTFA	92	58.209	ENSPANG00000023749	MYOCD	99	36.373	Papio_anubis
ENSG00000196588	MRTFA	67	53.039	ENSPKIG00000020636	-	93	50.000	Paramormyrops_kingsleyae
ENSG00000196588	MRTFA	92	95.522	ENSPKIG00000004053	mrtfab	80	49.515	Paramormyrops_kingsleyae
ENSG00000196588	MRTFA	62	91.000	ENSPKIG00000022392	mrtfba	76	52.473	Paramormyrops_kingsleyae
ENSG00000196588	MRTFA	92	97.015	ENSPKIG00000001046	-	64	53.785	Paramormyrops_kingsleyae
ENSG00000196588	MRTFA	90	71.212	ENSPKIG00000003265	MYOCD	99	35.763	Paramormyrops_kingsleyae
ENSG00000196588	MRTFA	100	82.353	ENSPSIG00000007042	MRTFA	100	70.894	Pelodiscus_sinensis
ENSG00000196588	MRTFA	90	87.879	ENSPSIG00000006962	MRTFB	88	47.845	Pelodiscus_sinensis
ENSG00000196588	MRTFA	92	83.582	ENSPMGG00000002440	mrtfba	66	57.757	Periophthalmus_magnuspinnatus
ENSG00000196588	MRTFA	96	94.286	ENSPMGG00000007329	mrtfab	99	44.845	Periophthalmus_magnuspinnatus
ENSG00000196588	MRTFA	88	31.325	ENSPMGG00000004029	-	75	34.026	Periophthalmus_magnuspinnatus
ENSG00000196588	MRTFA	100	94.118	ENSPEMG00000003602	Mkl1	100	84.494	Peromyscus_maniculatus_bairdii
ENSG00000196588	MRTFA	92	85.075	ENSPEMG00000007057	Mkl2	79	50.235	Peromyscus_maniculatus_bairdii
ENSG00000196588	MRTFA	100	56.164	ENSPEMG00000010989	Myocd	99	36.481	Peromyscus_maniculatus_bairdii
ENSG00000196588	MRTFA	100	85.882	ENSPCIG00000020323	MRTFA	100	70.055	Phascolarctos_cinereus
ENSG00000196588	MRTFA	92	55.224	ENSPCIG00000009361	MYOCD	66	38.633	Phascolarctos_cinereus
ENSG00000196588	MRTFA	92	85.075	ENSPCIG00000012142	MRTFB	83	49.925	Phascolarctos_cinereus
ENSG00000196588	MRTFA	92	98.507	ENSPFOG00000017227	mrtfab	76	53.175	Poecilia_formosa
ENSG00000196588	MRTFA	92	74.627	ENSPFOG00000010759	mrtfbb	76	45.271	Poecilia_formosa
ENSG00000196588	MRTFA	62	34.805	ENSPFOG00000018965	-	82	33.672	Poecilia_formosa
ENSG00000196588	MRTFA	92	83.582	ENSPFOG00000004404	mrtfba	99	41.667	Poecilia_formosa
ENSG00000196588	MRTFA	92	74.627	ENSPLAG00000002349	mrtfbb	97	38.949	Poecilia_latipinna
ENSG00000196588	MRTFA	92	98.507	ENSPLAG00000001889	mrtfab	75	53.016	Poecilia_latipinna
ENSG00000196588	MRTFA	92	74.627	ENSPMEG00000019033	mrtfbb	61	46.238	Poecilia_mexicana
ENSG00000196588	MRTFA	64	38.645	ENSPMEG00000005523	-	59	37.072	Poecilia_mexicana
ENSG00000196588	MRTFA	93	98.529	ENSPMEG00000003751	mrtfab	80	53.333	Poecilia_mexicana
ENSG00000196588	MRTFA	90	60.606	ENSPREG00000020201	-	60	38.574	Poecilia_reticulata
ENSG00000196588	MRTFA	93	98.529	ENSPREG00000021039	mrtfab	66	53.772	Poecilia_reticulata
ENSG00000196588	MRTFA	92	83.582	ENSPREG00000016477	mrtfba	54	51.706	Poecilia_reticulata
ENSG00000196588	MRTFA	100	98.824	ENSPPYG00000011852	MRTFA	100	96.265	Pongo_abelii
ENSG00000196588	MRTFA	92	58.209	ENSPPYG00000007995	MYOCD	59	41.369	Pongo_abelii
ENSG00000196588	MRTFA	92	85.075	ENSPPYG00000007122	MRTFB	58	49.842	Pongo_abelii
ENSG00000196588	MRTFA	58	56.693	ENSPCAG00000006406	MYOCD	56	39.274	Procavia_capensis
ENSG00000196588	MRTFA	100	92.941	ENSPCAG00000004864	MRTFA	88	98.969	Procavia_capensis
ENSG00000196588	MRTFA	100	96.471	ENSPCOG00000018452	MRTFA	100	93.079	Propithecus_coquereli
ENSG00000196588	MRTFA	92	58.209	ENSPCOG00000028319	MYOCD	80	42.969	Propithecus_coquereli
ENSG00000196588	MRTFA	92	85.075	ENSPCOG00000020125	MRTFB	78	49.844	Propithecus_coquereli
ENSG00000196588	MRTFA	92	58.209	ENSPVAG00000017566	MYOCD	71	44.038	Pteropus_vampyrus
ENSG00000196588	MRTFA	90	86.364	ENSPVAG00000015462	MRTFB	85	47.368	Pteropus_vampyrus
ENSG00000196588	MRTFA	100	92.941	ENSPVAG00000014217	MRTFA	89	86.441	Pteropus_vampyrus
ENSG00000196588	MRTFA	90	92.424	ENSPNYG00000019235	-	63	46.117	Pundamilia_nyererei
ENSG00000196588	MRTFA	92	98.507	ENSPNYG00000003895	mrtfab	68	51.746	Pundamilia_nyererei
ENSG00000196588	MRTFA	56	38.330	ENSPNYG00000008372	-	55	40.458	Pundamilia_nyererei
ENSG00000196588	MRTFA	92	83.582	ENSPNYG00000002614	mrtfba	77	38.831	Pundamilia_nyererei
ENSG00000196588	MRTFA	92	95.522	ENSPNAG00000002883	mrtfab	71	54.146	Pygocentrus_nattereri
ENSG00000196588	MRTFA	97	74.648	ENSPNAG00000012079	mrtfbb	74	49.374	Pygocentrus_nattereri
ENSG00000196588	MRTFA	92	79.104	ENSPNAG00000026256	MYOCD	82	39.483	Pygocentrus_nattereri
ENSG00000196588	MRTFA	92	85.075	ENSPNAG00000011420	mrtfba	73	52.901	Pygocentrus_nattereri
ENSG00000196588	MRTFA	100	57.534	ENSRNOG00000003669	Myocd	99	36.087	Rattus_norvegicus
ENSG00000196588	MRTFA	100	94.118	ENSRNOG00000018803	Mrtfa	100	84.639	Rattus_norvegicus
ENSG00000196588	MRTFA	92	85.075	ENSRBIG00000033416	MRTFB	95	42.651	Rhinopithecus_bieti
ENSG00000196588	MRTFA	84	55.738	ENSRBIG00000037138	MYOCD	67	40.484	Rhinopithecus_bieti
ENSG00000196588	MRTFA	100	98.824	ENSRBIG00000036684	MRTFA	100	96.598	Rhinopithecus_bieti
ENSG00000196588	MRTFA	100	98.824	ENSRROG00000042362	MRTFA	100	96.598	Rhinopithecus_roxellana
ENSG00000196588	MRTFA	92	85.075	ENSRROG00000009926	MRTFB	78	49.764	Rhinopithecus_roxellana
ENSG00000196588	MRTFA	92	56.716	ENSRROG00000030552	MYOCD	63	40.718	Rhinopithecus_roxellana
ENSG00000196588	MRTFA	92	58.209	ENSSBOG00000034713	MYOCD	99	35.687	Saimiri_boliviensis_boliviensis
ENSG00000196588	MRTFA	92	85.075	ENSSBOG00000033813	MRTFB	78	49.449	Saimiri_boliviensis_boliviensis
ENSG00000196588	MRTFA	100	97.647	ENSSBOG00000019487	MRTFA	100	94.356	Saimiri_boliviensis_boliviensis
ENSG00000196588	MRTFA	90	86.364	ENSSHAG00000000780	MRTFB	84	49.175	Sarcophilus_harrisii
ENSG00000196588	MRTFA	100	49.315	ENSSHAG00000002911	-	83	41.223	Sarcophilus_harrisii
ENSG00000196588	MRTFA	92	94.030	ENSSFOG00015011195	mkl1	68	53.756	Scleropages_formosus
ENSG00000196588	MRTFA	97	95.775	ENSSFOG00015004553	mrtfab	87	53.991	Scleropages_formosus
ENSG00000196588	MRTFA	92	86.567	ENSSFOG00015011587	-	82	49.781	Scleropages_formosus
ENSG00000196588	MRTFA	90	60.294	ENSSMAG00000005043	mrtfbb	64	66.116	Scophthalmus_maximus
ENSG00000196588	MRTFA	59	37.004	ENSSMAG00000002501	MYOCD	80	34.982	Scophthalmus_maximus
ENSG00000196588	MRTFA	90	84.848	ENSSMAG00000008135	mrtfba	70	48.636	Scophthalmus_maximus
ENSG00000196588	MRTFA	92	89.552	ENSSMAG00000006923	-	65	46.468	Scophthalmus_maximus
ENSG00000196588	MRTFA	90	84.848	ENSSDUG00000008600	mrtfba	73	51.241	Seriola_dumerili
ENSG00000196588	MRTFA	67	32.812	ENSSDUG00000012635	MYOCD	55	42.773	Seriola_dumerili
ENSG00000196588	MRTFA	90	95.455	ENSSDUG00000002030	-	57	50.235	Seriola_dumerili
ENSG00000196588	MRTFA	85	64.964	ENSSDUG00000019134	mrtfbb	79	46.820	Seriola_dumerili
ENSG00000196588	MRTFA	92	98.507	ENSSDUG00000007393	mrtfab	74	53.760	Seriola_dumerili
ENSG00000196588	MRTFA	90	93.939	ENSSLDG00000020708	-	56	50.000	Seriola_lalandi_dorsalis
ENSG00000196588	MRTFA	70	37.824	ENSSLDG00000002406	-	54	43.114	Seriola_lalandi_dorsalis
ENSG00000196588	MRTFA	92	79.104	ENSSLDG00000010820	mrtfbb	77	46.912	Seriola_lalandi_dorsalis
ENSG00000196588	MRTFA	92	83.582	ENSSLDG00000008000	mrtfba	53	52.901	Seriola_lalandi_dorsalis
ENSG00000196588	MRTFA	71	86.538	ENSSARG00000009416	MRTFB	84	45.597	Sorex_araneus
ENSG00000196588	MRTFA	89	60.000	ENSSARG00000007369	MYOCD	58	41.879	Sorex_araneus
ENSG00000196588	MRTFA	100	92.941	ENSSARG00000004057	MRTFA	91	82.085	Sorex_araneus
ENSG00000196588	MRTFA	85	55.224	ENSSPUG00000006103	MYOCD	80	42.014	Sphenodon_punctatus
ENSG00000196588	MRTFA	92	98.507	ENSSPAG00000005433	mrtfab	76	53.407	Stegastes_partitus
ENSG00000196588	MRTFA	90	90.909	ENSSPAG00000012935	-	65	46.538	Stegastes_partitus
ENSG00000196588	MRTFA	92	77.612	ENSSPAG00000013830	mrtfbb	55	45.118	Stegastes_partitus
ENSG00000196588	MRTFA	92	83.582	ENSSPAG00000015068	mrtfba	68	53.833	Stegastes_partitus
ENSG00000196588	MRTFA	92	59.701	ENSSSCG00000031988	MYOCD	99	37.062	Sus_scrofa
ENSG00000196588	MRTFA	92	85.075	ENSSSCG00000039171	MRTFB	84	47.273	Sus_scrofa
ENSG00000196588	MRTFA	100	94.118	ENSSSCG00000000075	MRTFA	94	86.464	Sus_scrofa
ENSG00000196588	MRTFA	92	97.015	ENSTGUG00000010083	MRTFA	100	70.415	Taeniopygia_guttata
ENSG00000196588	MRTFA	90	86.364	ENSTGUG00000005026	MRTFB	84	48.039	Taeniopygia_guttata
ENSG00000196588	MRTFA	92	82.090	ENSTGUG00000005789	MYOCD	64	42.590	Taeniopygia_guttata
ENSG00000196588	MRTFA	92	83.582	ENSTRUG00000016949	mrtfba	61	80.272	Takifugu_rubripes
ENSG00000196588	MRTFA	66	70.755	ENSTRUG00000011901	mrtfbb	61	41.638	Takifugu_rubripes
ENSG00000196588	MRTFA	65	34.082	ENSTRUG00000002497	MYOCD	83	39.184	Takifugu_rubripes
ENSG00000196588	MRTFA	59	97.674	ENSTNIG00000012948	mrtfab	99	48.103	Tetraodon_nigroviridis
ENSG00000196588	MRTFA	99	30.201	ENSTNIG00000011529	-	61	36.098	Tetraodon_nigroviridis
ENSG00000196588	MRTFA	90	84.848	ENSTNIG00000012918	mrtfba	74	51.966	Tetraodon_nigroviridis
ENSG00000196588	MRTFA	90	77.273	ENSTNIG00000018586	mrtfbb	79	43.393	Tetraodon_nigroviridis
ENSG00000196588	MRTFA	90	86.364	ENSTTRG00000006876	MRTFB	58	54.003	Tursiops_truncatus
ENSG00000196588	MRTFA	100	88.235	ENSTTRG00000011501	MRTFA	100	84.787	Tursiops_truncatus
ENSG00000196588	MRTFA	89	60.000	ENSTTRG00000002896	MYOCD	61	59.639	Tursiops_truncatus
ENSG00000196588	MRTFA	98	38.266	ENSUAMG00000008231	MYOCD	99	37.259	Ursus_americanus
ENSG00000196588	MRTFA	100	95.294	ENSUAMG00000004438	MRTFA	100	90.588	Ursus_americanus
ENSG00000196588	MRTFA	90	86.364	ENSUAMG00000026025	MRTFB	74	47.354	Ursus_americanus
ENSG00000196588	MRTFA	100	91.765	ENSUMAG00000014261	MRTFA	99	91.364	Ursus_maritimus
ENSG00000196588	MRTFA	92	85.075	ENSUMAG00000004446	MRTFB	85	47.413	Ursus_maritimus
ENSG00000196588	MRTFA	100	94.118	ENSVVUG00000006989	MRTFA	100	89.555	Vulpes_vulpes
ENSG00000196588	MRTFA	93	85.294	ENSVVUG00000019462	MRTFB	84	47.398	Vulpes_vulpes
ENSG00000196588	MRTFA	92	61.194	ENSVVUG00000029888	MYOCD	60	43.231	Vulpes_vulpes
ENSG00000196588	MRTFA	90	34.783	ENSXETG00000030651	-	62	33.950	Xenopus_tropicalis
ENSG00000196588	MRTFA	92	67.164	ENSXETG00000011035	myocd	82	42.063	Xenopus_tropicalis
ENSG00000196588	MRTFA	90	86.364	ENSXETG00000010993	mrtfb	73	50.751	Xenopus_tropicalis
ENSG00000196588	MRTFA	92	95.522	ENSXETG00000022963	mrtfa	69	57.168	Xenopus_tropicalis
ENSG00000196588	MRTFA	90	74.242	ENSXCOG00000011119	mrtfbb	82	43.269	Xiphophorus_couchianus
ENSG00000196588	MRTFA	100	60.465	ENSXCOG00000001482	mrtfab	93	54.082	Xiphophorus_couchianus
ENSG00000196588	MRTFA	92	74.627	ENSXMAG00000000094	mrtfbb	61	44.724	Xiphophorus_maculatus
ENSG00000196588	MRTFA	92	98.507	ENSXMAG00000009671	mrtfab	66	54.589	Xiphophorus_maculatus
ENSG00000196588	MRTFA	92	83.582	ENSXMAG00000010665	mrtfba	54	51.789	Xiphophorus_maculatus
ENSG00000196588	MRTFA	80	37.815	ENSXMAG00000001274	-	51	55.319	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003713	transcription coactivator activity	-	ISS	Function
GO:0003779	actin binding	24440334.	IDA	Function
GO:0003785	actin monomer binding	-	ISS	Function
GO:0005515	protein binding	12397177.14565952.19350017.	IPI	Function
GO:0005634	nucleus	14970199.24440334.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	14970199.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0010735	positive regulation of transcription via serum response element binding	24440334.	IDA	Process
GO:0030036	actin cytoskeleton organization	-	ISS	Process
GO:0043522	leucine zipper domain binding	14970199.	IPI	Function
GO:0045944	positive regulation of transcription by RNA polymerase II	14970199.	IDA	Process
GO:0051145	smooth muscle cell differentiation	21873635.	IBA	Process
GO:0051145	smooth muscle cell differentiation	14970199.	IMP	Process

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
29077787	miR-219a-5p inhibits breast cancer cell migration and epithelial-mesenchymal transition by targeting myocardin-related transcription factor A.	Acta Biochim Biophys Sin (Shanghai)	2017 Dec 1	Zhuang C	doi: 10.1093/abbs/gmx114.
20816842	Megakaryoblastic leukemia protein-1 (MKL1): Increasing evidence for an involvement in cancer progression and metastasis.	Int J Biochem Cell Biol	2010 Dec	Scharenberg MA	doi: 10.1016/j.biocel.2010.08.014
28218970	MKL1 is an epigenetic mediator of TNF-α-induced proinflammatory transcription in macrophages by interacting with ASH2.	FEBS Lett	2017 Mar	Song M	doi: 10.1002/1873-3468.12601
28035058	MRTF-A can activate Nrf2 to increase the resistance to doxorubicin.	Oncotarget	2017 Jan 31	Xu Y	doi: 10.18632/oncotarget.14246.
27708220	Myocardin-related transcription factor A (MRTF-A) activity-dependent cell adhesion is correlated to focal adhesion kinase (FAK) activity.	Oncotarget	2016 Nov 1	Kishi T	doi: 10.18632/oncotarget.12350.
26498848	The MRTF-A/B function as oncogenes in pancreatic cancer.	Oncol Rep	2016 Jan	Song Z	doi: 10.3892/or.2015.4329
27435395	miR-206 Inhibits Stemness and Metastasis of Breast Cancer by Targeting MKL1/IL11 Pathway.	Clin Cancer Res	2017 Feb 15	Samaeekia R	doi: 10.1158/1078-0432.CCR-16-0943
28893556	The ILK-MMP9-MRTF axis is crucial for EndMT differentiation of endothelial cells in a tumor microenvironment.	Biochim Biophys Acta Mol Cell Res	2017 Dec	Ciszewski WM	doi: 10.1016/j.bbamcr.2017.09.004
25854163	MRTF-A and STAT3 promote MDA-MB-231 cell migration via hypermethylating BRSM1.	IUBMB Life	2015 Mar	Xing WJ	doi: 10.1002/iub.1362
24495796	SAP domain-dependent Mkl1 signaling stimulates proliferation and cell migration by induction of a distinct gene set indicative of poor prognosis in breast cancer patients.	Mol Cancer	2014 Feb 5	Gurbuz I	doi: 10.1186/1476-4598-13-22.
25955685	miR-206 inhibits metastasis-relevant traits by degrading MRTF-A in anaplastic thyroid cancer.	Int J Oncol	2015 Jul	Zhang WL	doi: 10.3892/ijo.2015.2993
26476216	Transcriptional factors p300 and MRTF-A synergistically enhance the expression of migration-related genes in MCF-7 breast cancer cells.	Biochem Biophys Res Commun	2015 Nov 27	He H	doi: 10.1016/j.bbrc.2015.10.060
24189459	Histone methyltransferase SMYD3 promotes MRTF-A-mediated transactivation of MYL9 and migration of MCF-7 breast cancer cells.	Cancer Lett	2014 Mar 1	Luo XG	doi: 10.1016/j.canlet.2013.10.026
24084383	Myocardin-related transcription factor A is up-regulated by 17β-estradiol and promotes migration of MCF-7 breast cancer cells via transactivation of MYL9 and CYR61.	Acta Biochim Biophys Sin (Shanghai)	2013 Nov	Zhang C	doi: 10.1093/abbs/gmt104
24721635	Activation of the MKL1/actin signaling pathway induces hormonal escape in estrogen-responsive breast cancer cell lines.	Mol Cell Endocrinol	2014 Jun 5	Kerdivel G	doi: 10.1016/j.mce.2014.03.009
28385531	MKL1 links epigenetic activation of MMP2 to ovarian cancer cell migration and invasion.	Biochem Biophys Res Commun	2017 Jun 3	Xu W	doi: 10.1016/j.bbrc.2017.04.006
28499590	MiR-93-5p inhibits the EMT of breast cancer cells via targeting MKL-1 and STAT3.	Exp Cell Res	2017 Aug 1	Xiang Y	doi: 10.1016/j.yexcr.2017.05.007
28822708	MRTF-A-miR-206-WDR1 form feedback loop to regulate breast cancer cell migration.	Exp Cell Res	2017 Oct 15	Xiang Y	doi: 10.1016/j.yexcr.2017.08.023
28069441	Transcription of HOTAIR is regulated by RhoC-MRTF-A-SRF signaling pathway in human breast cancer cells.	Cell Signal	2017 Feb	He H	doi: 10.1016/j.cellsig.2017.01.003
30078679	Myocardin-related transcription factor A (MRTF-A) mediates doxorubicin-induced PERP transcription in colon cancer cells.	Biochem Biophys Res Commun	2018 Sep 10	Chen B	doi: 10.1016/j.bbrc.2018.07.106
30038252	Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization.	Nat Cell Biol	2018 Aug	Er EE	doi: 10.1038/s41556-018-0138-8

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr22	40411496	Missense_Mutation	novel	G897D	0.43
BLCA	chr22	40418488	Silent	NA	I650I	0.07
BLCA	chr22	40435550	Missense_Mutation	novel	L4F	0.36
BLCA	chr22	40463356	Intron	novel		0.51
BLCA	chr22	40424222	Missense_Mutation	novel	S154C	0.42
BLCA	chr22	40424345	Missense_Mutation	novel	S113C	0.44
BLCA	chr22	40423587	Silent	novel	L192L	0.34
BRCA	chr22	40418947	Silent	rs746901961	L497L	0.13
BRCA	chr22	40463358	Intron	novel		0.52
BRCA	chr22	40429735	Nonsense_Mutation	NA	Q58*	0.38
BRCA	chr22	40429705	Missense_Mutation	NA	D68N	0.25
BRCA	chr22	40463316	Intron	novel		0.13
BRCA	chr22	40463372	Intron	novel		0.18
BRCA	chr22	40411867	Silent	NA	G773G	0.36
BRCA	chr22	40463263	5'UTR	NA		0.19
BRCA	chr22	40410505	3'UTR	novel		0.58
CESC	chr22	40519227	Intron	NA		0.63
CESC	chr22	40420966	Frame_Shift_Del	novel	*M255Wfs82**	0.2
CESC	chr22	40463354	Intron	novel		0.2
CESC	chr22	40420463	Missense_Mutation	novel	N332S	0.32
CESC	chr22	40424322	Missense_Mutation	rs149542196	D121N	0.38
CESC	chr22	40420996	Frame_Shift_Ins	NA	*D245Gfs72**	0.3
CESC	chr22	40410507	3'UTR	rs535310586		0.65
CESC	chr22	40424307	Missense_Mutation	rs138116355	E126K	0.42
CESC	chr22	40420408	Missense_Mutation	NA	M350I	0.37
CESC	chr22	40411542	Missense_Mutation	novel	D882N	0.27
COAD	chr22	40418877	Missense_Mutation	rs373666097	R521C	0.19
COAD	chr22	40418405	Missense_Mutation	novel	S678N	0.04
COAD	chr22	40423660	Missense_Mutation	rs202202963	R168Q	0.33
COAD	chr22	40419059	Missense_Mutation	rs140573764	R460H	0.27
COAD	chr22	40411906	Missense_Mutation	novel	E760D	0.11
COAD	chr22	40411270	3'UTR	novel		0.25
COAD	chr22	40419002	Missense_Mutation	NA	M479T	0.41
COAD	chr22	40420925	In_Frame_Ins	NA	Q267dup	0.26
COAD	chr22	40420538	Frame_Shift_Del	rs771550496	*P307Qfs30**	0.33
COAD	chr22	40411473	Frame_Shift_Del	novel	*L905Sfs62**	0.31
COAD	chr22	40418612	Missense_Mutation	NA	I609T	0.46
COAD	chr22	40463251	5'UTR	novel		0.4
COAD	chr22	40411826	Frame_Shift_Ins	NA	*L787Pfs10**	0.56
COAD	chr22	40435507	Missense_Mutation	rs780892147	R19W	0.35
COAD	chr22	40411827	Frame_Shift_Del	NA	*L787Wfs41**	0.28
COAD	chr22	40411613	Frame_Shift_Del	NA	*P858Rfs43**	0.34
COAD	chr22	40418578	Silent	rs753792370	S620S	0.46
COAD	chr22	40418615	Missense_Mutation	novel	H608R	0.39
COAD	chr22	40420996	Frame_Shift_Ins	NA	*D245Gfs72**	0.28
COAD	chr22	40411710	Missense_Mutation	novel	L826M	0.35
COAD	chr22	40420537	Frame_Shift_Ins	rs34028511	*V308Sfs9**	0.5
COAD	chr22	40411636	Silent	NA	S850S	0.38
COAD	chr22	40431433	Silent	rs557959154	S37S	0.43
COAD	chr22	40420997	Frame_Shift_Del	novel	*P244Rfs93**	0.47
COAD	chr22	40420538	Frame_Shift_Del	rs771550496	*P307Qfs30**	0.41
COAD	chr22	40411662	Missense_Mutation	rs148866820	D842N	0.44
ESCA	chr22	40420958	Missense_Mutation	novel	S257L	0.08
GBM	chr22	40420955	Missense_Mutation	NA	S258C	0.65
GBM	chr22	40411749	Missense_Mutation	rs575546439	R813C	0.47
GBM	chr22	40418900	Missense_Mutation	NA	G513E	0.35
GBM	chr22	40417007	Missense_Mutation	novel	D753N	0.14
GBM	chr22	40421007	Missense_Mutation	novel	Y241N	0.06
GBM	chr22	40419365	Frame_Shift_Del	novel	*E358Gfs2**	0.4
HNSC	chr22	40411345	3'UTR	novel		0.33
HNSC	chr22	40423559	Missense_Mutation	novel	K202E	0.16
HNSC	chr22	40419312	Missense_Mutation	NA	R376C	0.24
HNSC	chr22	40431453	Missense_Mutation	rs772930139	R31C	0.37
HNSC	chr22	40429646	Missense_Mutation	novel	N87K	0.71
HNSC	chr22	40429657	Missense_Mutation	novel	V84M	0.08
HNSC	chr22	40419256	Silent	novel	P394P	0.25
HNSC	chr22	40421046	Nonsense_Mutation	novel	E228*	0.08
KIRC	chr22	40411849	Silent	novel	P779P	0.3
KIRC	chr22	40435549	Missense_Mutation	NA	K5E	0.34
KIRC	chr22	40411473	Missense_Mutation	novel	L905F	0.13
KIRP	chr22	40420556	In_Frame_Del	novel	G301del	0.45
KIRP	chr22	40418963	Missense_Mutation	rs199908950	S492L	0.2
KIRP	chr22	40418876	Missense_Mutation	rs775640702	R521H	0.23
KIRP	chr22	40429745	Silent	NA	L54L	0.26
KIRP	chr22	40429746	Missense_Mutation	NA	L54P	0.26
LGG	chr22	40411843	Frame_Shift_Del	novel	*T781Sfs15**	0.04
LGG	chr22	40429625	Silent	novel	S94S	0.48
LGG	chr22	40431449	Missense_Mutation	novel	S32Y	0.07
LGG	chr22	40463338	Intron	novel		0.07
LIHC	chr22	40463322	Intron	novel		0.32
LUAD	chr22	40429743	Missense_Mutation	novel	Q55R	0.16
LUAD	chr22	40420864	Silent	novel	I288I	0.09
LUAD	chr22	40429656	Missense_Mutation	NA	V84E	0.15
LUAD	chr22	40463295	Intron	novel		0.06
LUSC	chr22	40424244	Nonsense_Mutation	novel	E147*	0.25
LUSC	chr22	40420470	Missense_Mutation	NA	R330C	0.57
LUSC	chr22	40418933	Missense_Mutation	novel	G502D	0.16
LUSC	chr22	40420414	Missense_Mutation	novel	D348E	0.32
LUSC	chr22	40423595	Missense_Mutation	novel	P190S	0.25
LUSC	chr22	40418891	Missense_Mutation	rs762204984	A516V	0.42
LUSC	chr22	40420849	Splice_Region	NA	P293P	0.26
LUSC	chr22	40417402	Missense_Mutation	novel	S719C	0.18
LUSC	chr22	40418485	Missense_Mutation	novel	K651N	0.19
LUSC	chr22	40423616	Missense_Mutation	NA	P183S	0.17
LUSC	chr22	40424337	Missense_Mutation	rs779073393	D116N	0.56
LUSC	chr22	40419098	Missense_Mutation	rs780407081	T447M	0.83
LUSC	chr22	40424322	Missense_Mutation	rs149542196	D121N	0.18
LUSC	chr22	40423593	Silent	novel	P190P	0.06
LUSC	chr22	40429649	Silent	NA	K86K	0.28
OV	chr22	40420549	Frame_Shift_Del	novel	*L300Gfs33**	0.46
OV	chr22	40429754	Silent	NA	E51E	0.11
OV	chr22	40420955	Missense_Mutation	NA	S258C	0.84
OV	chr22	40429652	Missense_Mutation	NA	E85D	0.17
OV	chr22	40463316	Intron	novel		0.06
OV	chr22	40420957	Silent	novel	S257S	0.13
OV	chr22	40431429	Missense_Mutation	NA	L39V	0.34
OV	chr22	40418886	Missense_Mutation	NA	L518V	0.38
PAAD	chr22	40424372	Missense_Mutation	novel	V104G	0.04
PAAD	chr22	40418824	Silent	rs373988834	T538T	0.2
PAAD	chr22	40421017	Silent	novel	K237K	0.18
PRAD	chr22	40419311	Missense_Mutation	NA	R376H	0.13
PRAD	chr22	40424287	Silent	rs751238821	E132E	0.24
READ	chr22	40418963	Missense_Mutation	rs199908950	S492L	0.28
READ	chr22	40411827	Frame_Shift_Del	NA	*L787Wfs41**	0.49
READ	chr22	40419354	Nonsense_Mutation	rs371934037	R362*	0.3
SKCM	chr22	40423554	Silent	rs771855607	S203S	0.26
SKCM	chr22	40431434	Missense_Mutation	rs780837181	S37L	0.42
SKCM	chr22	40419378	Missense_Mutation	NA	E354K	0.38
SKCM	chr22	40431447	Missense_Mutation	NA	R33W	0.45
SKCM	chr22	40418607	Missense_Mutation	NA	P611S	0.28
SKCM	chr22	40419207	Missense_Mutation	NA	P411S	0.31	SAP
SKCM	chr22	40431453	Missense_Mutation	rs772930139	R31C	0.34
SKCM	chr22	40418591	Missense_Mutation	rs201542621	P616L	0.44
SKCM	chr22	40424215	Silent	NA	S156S	0.48
SKCM	chr22	40424308	Silent	novel	P125P	0.48
SKCM	chr22	40418532	Missense_Mutation	rs758482858	P636S	0.22
SKCM	chr22	40431448	Silent	rs536284634	S32S	0.16
SKCM	chr22	40429615	Missense_Mutation	novel	A98T	0.13
SKCM	chr22	40431461	Missense_Mutation	NA	R28Q	0.06
SKCM	chr22	40420863	Silent	rs766158109	L289L	0.21
SKCM	chr22	40420968	Missense_Mutation	NA	P254S	0.26
SKCM	chr22	40420921	Silent	novel	F269F	0.42
SKCM	chr22	40423549	Missense_Mutation	NA	P205L	0.28
SKCM	chr22	40417456	Missense_Mutation	NA	S701F	0.17
SKCM	chr22	40418452	Silent	rs777904504	S662S	0.6
SKCM	chr22	40418642	Missense_Mutation	NA	P599L	0.24
SKCM	chr22	40424306	Missense_Mutation	NA	E126G	0.06
SKCM	chr22	40431447	Missense_Mutation	NA	R33W	0.49
SKCM	chr22	40419331	Silent	novel	T369T	0.78
SKCM	chr22	40420539	Missense_Mutation	novel	P307S	0.8
SKCM	chr22	40420942	Silent	novel	I262I	0.52
STAD	chr22	40411693	Silent	rs747371545	H831H	0.17
STAD	chr22	40463223	Missense_Mutation	NA	P2R	0.07
STAD	chr22	40420538	Frame_Shift_Del	rs771550496	*P307Qfs30**	0.25
STAD	chr22	40411335	3'UTR	rs568808009		0.18
STAD	chr22	40420928	Missense_Mutation	novel	Q267L	0.27
STAD	chr22	40419312	Missense_Mutation	NA	R376C	0.29
STAD	chr22	40424307	Missense_Mutation	rs138116355	E126K	0.32
STAD	chr22	40418408	Missense_Mutation	NA	D677G	0.27
STAD	chr22	40423668	Silent	rs779867177	P165P	0.26
STAD	chr22	40463363	Intron	novel		0.31
STAD	chr22	40429689	Missense_Mutation	novel	K73M	0.45
STAD	chr22	40435514	Silent	novel	S16S	0.09
STAD	chr22	40420997	Frame_Shift_Del	novel	*P244Rfs93**	0.37
STAD	chr22	40418581	Silent	rs372005183	P619P	0.24
STAD	chr22	40435507	Missense_Mutation	rs780892147	R19W	0.13
STAD	chr22	40419354	Nonsense_Mutation	rs371934037	R362*	0.11
STAD	chr22	40463222	Splice_Region	NA	P2P	0.22
STAD	chr22	40418972	Missense_Mutation	NA	L489P	0.18
STAD	chr22	40420538	Frame_Shift_Del	rs771550496	*P307Qfs30**	0.29
STAD	chr22	40418947	Silent	NA	L497L	0.27
STAD	chr22	40418860	Missense_Mutation	NA	M526I	0.38
STAD	chr22	40420538	Frame_Shift_Del	rs771550496	*P307Qfs30**	0.32
STAD	chr22	40431403	Splice_Site	NA	X47_splice	0.27
STAD	chr22	40419088	Silent	rs142878790	T450T	0.21
STAD	chr22	40418983	Silent	rs751490538	T485T	0.21
THCA	chr22	40419087	Missense_Mutation	rs752603698	P451S	0.63
UCEC	chr22	40411909	Splice_Site	novel	X760_splice	0.65
UCEC	chr22	40463263	5'UTR	NA		0.47
UCEC	chr22	40411431	Missense_Mutation	NA	D919N	0.27
UCEC	chr22	40419225	Missense_Mutation	rs750511313	E405K	0.37	SAP
UCEC	chr22	40431453	Missense_Mutation	NA	R31S	0.32
UCEC	chr22	40411791	Frame_Shift_Del	novel	*Q799Rfs29**	0.35
UCEC	chr22	40421046	Missense_Mutation	NA	E228K	0.41
UCEC	chr22	40420950	Missense_Mutation	rs757570875	A260T	0.45
UCEC	chr22	40463384	Intron	novel		0.42
UCEC	chr22	40411612	Silent	rs538107883	P858P	0.26
UCEC	chr22	40418813	Missense_Mutation	rs770900337	R542Q	0.55
UCEC	chr22	40420567	Silent	rs180736162	G297G	0.36
UCEC	chr22	40420852	Silent	NA	P292P	0.27
UCEC	chr22	40429663	Missense_Mutation	NA	E82K	0.3
UCEC	chr22	40420508	Missense_Mutation	novel	S317N	0.36
UCEC	chr22	40420899	Missense_Mutation	novel	Q277K	0.19
UCEC	chr22	40463372	Intron	novel		0.19
UCEC	chr22	40411303	3'UTR	novel		0.21
UCEC	chr22	40431435	Missense_Mutation	novel	S37P	0.31
UCEC	chr22	40423669	Missense_Mutation	rs543778985	P165L	0.34
UCEC	chr22	40417488	Silent	rs781262241	S690S	0.29
UCEC	chr22	40420891	Silent	novel	Q279Q	0.41
UCEC	chr22	40431434	Missense_Mutation	rs780837181	S37L	0.33
UCEC	chr22	40463360	Intron	novel		0.57
UCEC	chr22	40429693	Nonsense_Mutation	novel	E72*	0.5
UCEC	chr22	40463406	Intron	novel		0.17
UCEC	chr22	40418523	Frame_Shift_Del	NA	*Q639Sfs33**	0.38
UCEC	chr22	40420538	Frame_Shift_Del	rs771550496	*P307Qfs30**	0.35
UCEC	chr22	40420995	Frame_Shift_Del	NA	*D245Tfs92**	0.31
UCEC	chr22	40411526	Missense_Mutation	novel	S887N	0.22
UCEC	chr22	40435510	Missense_Mutation	novel	E18K	0.21
UCEC	chr22	40411662	Missense_Mutation	rs148866820	D842N	0.31
UCEC	chr22	40431433	Silent	rs557959154	S37S	0.33
UCEC	chr22	40411166	3'UTR	novel		0.3
UCEC	chr22	40410504	3'UTR	novel		0.46
UCEC	chr22	40420468	Silent	novel	R330R	0.35
UCEC	chr22	40424224	Silent	novel	T153T	0.26
UCEC	chr22	40420945	Missense_Mutation	NA	K261N	0.31
UCEC	chr22	40411372	3'UTR	novel		0.08
UCEC	chr22	40552267	5'UTR	novel		0.29
UCEC	chr22	40419202	Silent	rs768396546	A412A	0.39
UCEC	chr22	40419231	Missense_Mutation	rs766920620	A403T	0.3	SAP
UCEC	chr22	40420996	Frame_Shift_Ins	NA	*D245Gfs72**	0.33
UCEC	chr22	40435526	Missense_Mutation	rs371095439	E12D	0.29
UCEC	chr22	40429642	Missense_Mutation	novel	L89I	0.15
UCEC	chr22	40552293	5'UTR	novel		0.44
UCEC	chr22	40431446	Missense_Mutation	novel	R33Q	0.26
UCEC	chr22	40424307	Missense_Mutation	rs138116355	E126K	0.54
UCEC	chr22	40431473	Missense_Mutation	novel	D24G	0.5
UCEC	chr22	40420973	Missense_Mutation	novel	A252V	0.37
UVM	chr22	40424357	Missense_Mutation	novel	V109A	0.08

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRP	DEL	0.1563	0.08832
PAAD	DEL	0.1739	0.2014
PCPG	DEL	0.3395	0.044123
READ	DEL	0.3091	0.19022
SARC	AMP	0.2101	0.15096
THCA	DEL	0.1583	0.046486
THYM	DEL	0.065	0.063154

Survival Analysis

Cancer	P-value	Q-value
THYM	0.026	Kaplan-Meier Survival Analysis
KIRC	0.0002	Kaplan-Meier Survival Analysis
SARC	0.0076	Kaplan-Meier Survival Analysis
SKCM	0.0098	Kaplan-Meier Survival Analysis
BRCA	0.0063	Kaplan-Meier Survival Analysis
ESCA	0.0028	Kaplan-Meier Survival Analysis
LAML	0.0068	Kaplan-Meier Survival Analysis
LIHC	0.002	Kaplan-Meier Survival Analysis
LGG	0.024	Kaplan-Meier Survival Analysis
LUAD	0.017	Kaplan-Meier Survival Analysis
OV	0.00057	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742