EuRBPDB

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000196943 (Gene tree)
Gene ID: 161424
Gene Symbol: NOP9
Alias: C14orf21
Full Name: NOP9 nucleolar protein
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 9,273 bases
Position: chr14:24,299,854-24,309,126
Accession: 19826
RBP type: non-canonical RBP
Summary: (NOP9 Nucleolar Protein) is a Protein Coding gene. Diseases associated with NOP9 include Specific Language Impairment. Gene Ontology (GO) annotations related to this gene include binding.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
17956976	Nop9 is an RNA binding protein present in pre-40S ribosomes and required for 18S rRNA synthesis in yeast.	RNA	2007 Dec	Thomson E	-
28053123	Nop9 binds the central pseudoknot region of 18S rRNA.	Nucleic Acids Res	2017 Apr 7	Wang B	doi: 10.1093/nar/gkw1323.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000557362	NOP9-203	455	-	ENSP00000451905	97 (aa)	-	H0YJP7
ENST00000396802	NOP9-202	1942	-	ENSP00000380020	535 (aa)	-	Q86U38
ENST00000267425	NOP9-201	6033	XM_005267385	ENSP00000267425	636 (aa)	XP_005267442	Q86U38
ENST00000650565	NOP9-204	2139	-	ENSP00000497287	456 (aa)	-	-

Gene Model

Click here to download ENSG00000196943's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000196943	Language Disorders	4E-8	24571439

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000196943	rs4280164	14	24302079	G	Parent of origin effect on language impairment (paternal)	24571439	[NR] unit increase	3.872	EFO_0005425

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000196943's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000196943	NOP9	99	84.327	ENSMUSG00000019297	Nop9	100	82.075	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005575	cellular_component	-	ND	Component
GO:0008150	biological_process	-	ND	Process