EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000198538 (Gene tree)
Gene ID: 7576
Gene Symbol: ZNF28
Alias: KOX24|DKFZp781D0275
Full Name: zinc finger protein 28
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 60,193 bases
Position: chr19:52,797,408-52,857,600
Accession: 13073
RBP type: canonical RBP
Summary: ZNF28 (Zinc Finger Protein 28) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and DNA-binding transcription factor activity. An important paralog of this gene is ZNF836.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000412143	zf-C2H2	PF00096.26	7.6e-86	1	15
ENSP00000412143	zf-C2H2	PF00096.26	7.6e-86	2	15
ENSP00000412143	zf-C2H2	PF00096.26	7.6e-86	3	15
ENSP00000412143	zf-C2H2	PF00096.26	7.6e-86	4	15
ENSP00000412143	zf-C2H2	PF00096.26	7.6e-86	5	15
ENSP00000412143	zf-C2H2	PF00096.26	7.6e-86	6	15
ENSP00000412143	zf-C2H2	PF00096.26	7.6e-86	7	15
ENSP00000412143	zf-C2H2	PF00096.26	7.6e-86	8	15
ENSP00000412143	zf-C2H2	PF00096.26	7.6e-86	9	15
ENSP00000412143	zf-C2H2	PF00096.26	7.6e-86	10	15
ENSP00000412143	zf-C2H2	PF00096.26	7.6e-86	11	15
ENSP00000412143	zf-C2H2	PF00096.26	7.6e-86	12	15
ENSP00000412143	zf-C2H2	PF00096.26	7.6e-86	13	15
ENSP00000412143	zf-C2H2	PF00096.26	7.6e-86	14	15
ENSP00000412143	zf-C2H2	PF00096.26	7.6e-86	15	15
ENSP00000397693	zf-C2H2	PF00096.26	3.6e-85	1	15
ENSP00000397693	zf-C2H2	PF00096.26	3.6e-85	2	15
ENSP00000397693	zf-C2H2	PF00096.26	3.6e-85	3	15
ENSP00000397693	zf-C2H2	PF00096.26	3.6e-85	4	15
ENSP00000397693	zf-C2H2	PF00096.26	3.6e-85	5	15
ENSP00000397693	zf-C2H2	PF00096.26	3.6e-85	6	15
ENSP00000397693	zf-C2H2	PF00096.26	3.6e-85	7	15
ENSP00000397693	zf-C2H2	PF00096.26	3.6e-85	8	15
ENSP00000397693	zf-C2H2	PF00096.26	3.6e-85	9	15
ENSP00000397693	zf-C2H2	PF00096.26	3.6e-85	10	15
ENSP00000397693	zf-C2H2	PF00096.26	3.6e-85	11	15
ENSP00000397693	zf-C2H2	PF00096.26	3.6e-85	12	15
ENSP00000397693	zf-C2H2	PF00096.26	3.6e-85	13	15
ENSP00000397693	zf-C2H2	PF00096.26	3.6e-85	14	15
ENSP00000397693	zf-C2H2	PF00096.26	3.6e-85	15	15
ENSP00000375661	zf-C2H2	PF00096.26	6e-62	1	12
ENSP00000375661	zf-C2H2	PF00096.26	6e-62	2	12
ENSP00000375661	zf-C2H2	PF00096.26	6e-62	3	12
ENSP00000375661	zf-C2H2	PF00096.26	6e-62	4	12
ENSP00000375661	zf-C2H2	PF00096.26	6e-62	5	12
ENSP00000375661	zf-C2H2	PF00096.26	6e-62	6	12
ENSP00000375661	zf-C2H2	PF00096.26	6e-62	7	12
ENSP00000375661	zf-C2H2	PF00096.26	6e-62	8	12
ENSP00000375661	zf-C2H2	PF00096.26	6e-62	9	12
ENSP00000375661	zf-C2H2	PF00096.26	6e-62	10	12
ENSP00000375661	zf-C2H2	PF00096.26	6e-62	11	12
ENSP00000375661	zf-C2H2	PF00096.26	6e-62	12	12
ENSP00000375661	zf-met	PF12874.7	4.3e-17	1	3
ENSP00000375661	zf-met	PF12874.7	4.3e-17	2	3
ENSP00000375661	zf-met	PF12874.7	4.3e-17	3	3
ENSP00000412143	zf-met	PF12874.7	5e-15	1	3
ENSP00000412143	zf-met	PF12874.7	5e-15	2	3
ENSP00000412143	zf-met	PF12874.7	5e-15	3	3
ENSP00000397693	zf-met	PF12874.7	2e-14	1	2
ENSP00000397693	zf-met	PF12874.7	2e-14	2	2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000339844	ZNF28-201	650	-	ENSP00000344777	79 (aa)	-	F8WBV3
ENST00000464469	ZNF28-205	394	-	-	- (aa)	-	-
ENST00000542421	ZNF28-206	228	-	-	- (aa)	-	-
ENST00000596559	ZNF28-208	628	-	ENSP00000471448	175 (aa)	-	M0R0U4
ENST00000594602	ZNF28-207	684	-	ENSP00000469381	129 (aa)	-	M0QXU3
ENST00000438150	ZNF28-203	5171	XM_024451686	ENSP00000412143	665 (aa)	XP_024307454	P17035
ENST00000391783	ZNF28-202	1827	-	ENSP00000375661	546 (aa)	-	C9K0H3
ENST00000457749	ZNF28-204	4556	XM_006723354	ENSP00000397693	718 (aa)	XP_006723417	P17035

Gene Model

Click here to download ENSG00000198538's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000198538	rs140094156	19	52809791	T	Diverticular disease	30177863	[NR] unit increase	0.0068326	EFO_1001460
ENSG00000198538	rs2013647	19	52827416	?	Adolescent idiopathic scoliosis	30019117			EFO_0005423

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000198538's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000198538	ZNF28	100	91.365	ENSCATG00000035314	ZNF28	100	91.365	Cercocebus_atys
ENSG00000198538	ZNF28	100	81.239	ENSCSAG00000001970	ZNF28	99	82.008	Chlorocebus_sabaeus
ENSG00000198538	ZNF28	100	91.504	ENSCANG00000031963	ZNF28	100	91.504	Colobus_angolensis_palliatus
ENSG00000198538	ZNF28	100	98.496	ENSGGOG00000011362	ZNF28	100	98.468	Gorilla_gorilla
ENSG00000198538	ZNF28	100	91.365	ENSMMUG00000047412	ZNF28	100	91.365	Macaca_mulatta
ENSG00000198538	ZNF28	100	91.365	ENSMNEG00000042815	ZNF28	100	91.365	Macaca_nemestrina
ENSG00000198538	ZNF28	100	91.465	ENSMLEG00000041213	ZNF28	100	91.465	Mandrillus_leucophaeus
ENSG00000198538	ZNF28	100	93.457	ENSNLEG00000006051	ZNF28	100	93.457	Nomascus_leucogenys
ENSG00000198538	ZNF28	100	98.156	ENSPTRG00000048860	ZNF28	100	98.156	Pan_troglodytes
ENSG00000198538	ZNF28	100	93.454	ENSPPYG00000010341	ZNF28	100	93.454	Pongo_abelii
ENSG00000198538	ZNF28	100	90.211	ENSRBIG00000037464	ZNF28	100	89.765	Rhinopithecus_bieti
ENSG00000198538	ZNF28	100	91.504	ENSRROG00000032344	ZNF28	100	91.504	Rhinopithecus_roxellana
ENSG00000198538	ZNF28	100	77.816	ENSRROG00000030824	-	100	70.735	Rhinopithecus_roxellana

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	19274049.	NAS	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0046872	metal ion binding	-	IEA	Function