EuRBPDB

Description

Ensembl ID: ENSG00000198677 (Gene tree)
Gene ID: 9652
Gene Symbol: TTC37
Alias: THES|KIAA0372
Full Name: tetratricopeptide repeat domain 37
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 93,253 bases
Position: chr5:95,461,755-95,555,007
Accession: 23639
RBP type: non-canonical RBP
Summary: This gene encodes a protein with twenty tetratricopeptide (TPR) repeats. Tetratricopeptide repeat containing motifs are found in a variety of proteins and may mediate protein-protein interactions and chaperone activity. Mutations in this gene are associated with trichohepatoenteric syndrome. [provided by RefSeq, Jul 2010]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
22114319	The crystal structure of S. cerevisiae Ski2, a DExH helicase associated with the cytoplasmic functions of the exosome.	RNA	2012 Jan	Halbach F	doi: 10.1261/rna.029553.111
23953113	The yeast ski complex: crystal structure and RNA channeling to the exosome complex.	Cell	2013 Aug 15	Halbach F	doi: 10.1016/j.cell.2013.07.017.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000510228	TTC37-209	511	-	-	- (aa)	-	-
ENST00000358746	TTC37-201	5706	-	ENSP00000351596	1564 (aa)	-	Q6PGP7
ENST00000649566	TTC37-216	8038	-	ENSP00000497948	1564 (aa)	-	UPI00000709BD
ENST00000515176	TTC37-214	508	-	-	- (aa)	-	-
ENST00000505578	TTC37-205	664	-	ENSP00000423141	130 (aa)	-	H0Y964
ENST00000507805	TTC37-207	1321	-	-	- (aa)	-	-
ENST00000512026	TTC37-210	785	-	-	- (aa)	-	-
ENST00000506007	TTC37-206	884	-	-	- (aa)	-	-
ENST00000504421	TTC37-204	337	-	-	- (aa)	-	-
ENST00000503279	TTC37-203	583	-	-	- (aa)	-	-
ENST00000513232	TTC37-211	797	-	ENSP00000422749	33 (aa)	-	H0Y915
ENST00000508181	TTC37-208	872	-	-	- (aa)	-	-
ENST00000513823	TTC37-212	577	-	ENSP00000425403	95 (aa)	-	D6RDA0
ENST00000515207	TTC37-215	810	-	-	- (aa)	-	-
ENST00000502768	TTC37-202	917	-	-	- (aa)	-	-
ENST00000514952	TTC37-213	2102	-	ENSP00000423742	611 (aa)	-	D6RCE2

Gene Model

Pathways

Pathway ID	Pathway Name	Source
hsa03018	RNA degradation	KEGG

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000198677	TTC37	84	34.831	YPR189W	SKI3	61	34.831	Saccharomyces_cerevisiae

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	16024656.	IPI	Function
GO:0005634	nucleus	16024656.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005737	cytoplasm	16024656.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0035327	transcriptionally active chromatin	16024656.	IDA	Component
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	-	TAS	Process
GO:0055087	Ski complex	16024656.	IDA	Component