EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000198700 (Gene tree)
Gene ID: 55705
Gene Symbol: IPO9
Alias: Imp9|FLJ10402
Full Name: importin 9
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 55,154 bases
Position: chr1:201,829,141-201,884,294
Accession: 19425
RBP type: canonical RBP
Summary: (Importin 9) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include binding and protein transporter activity. An important paralog of this gene is IPO7.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000354742	IBN_N	PF03810.19	6e-09	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000361565	IPO9-201	11435	-	ENSP00000354742	1041 (aa)	-	Q96P70
ENST00000464348	IPO9-203	838	-	-	- (aa)	-	-
ENST00000456707	IPO9-202	609	-	ENSP00000387761	155 (aa)	-	Q5SVH5
ENST00000479374	IPO9-204	704	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000198700's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000198700	Hippocampus	1.11522131269546E-7	17903297
ENSG00000198700	Hippocampus	4.2312988448719E-7	17903297
ENSG00000198700	Hippocampus	2.50049219155511E-7	17903297
ENSG00000198700	Hippocampus	8.0471504544005E-7	17903297
ENSG00000198700	Hippocampus	1.64241994930821E-7	17903297
ENSG00000198700	Hippocampus	8.14965266012016E-7	17903297

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000198700	rs1517810	1	201880929	T	Cognitive performance (MTAG)	30038396	[0.011-0.02] unit increase	0.0153	EFO_0008354
ENSG00000198700	rs2494114	1	201831883	C	Body mass index	30108127	[NR] unit decrease	0.027	EFO_0004340
ENSG00000198700	rs8024	1	201876447	A	Educational attainment (years of education)	30038396	[0.0086-0.0144] unit decrease	0.0115	EFO_0004784
ENSG00000198700	rs2678204	1	201831383	?	Body mass index	30595370			EFO_0004340
ENSG00000198700	rs2644111	1	201832924	?	Fat-free mass	30593698	[0.15-0.29] unit increase	0.21731	EFO_0004995
ENSG00000198700	rs2644111	1	201832924	?	Fat-free mass	30593698	[0.12-0.21] unit increase	0.16548	EFO_0004995

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000198700's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000198700	IPO9	100	84.814	ENSAPOG00000020880	ipo9	99	85.673	Acanthochromis_polyacanthus
ENSG00000198700	IPO9	100	99.139	ENSAMEG00000012052	IPO9	100	99.139	Ailuropoda_melanoleuca
ENSG00000198700	IPO9	87	88.742	ENSACIG00000015855	ipo9	97	89.574	Amphilophus_citrinellus
ENSG00000198700	IPO9	100	86.998	ENSAOCG00000000358	ipo9	99	87.984	Amphiprion_ocellaris
ENSG00000198700	IPO9	100	87.094	ENSAPEG00000009684	ipo9	98	89.686	Amphiprion_percula
ENSG00000198700	IPO9	85	89.266	ENSATEG00000025038	ipo9	97	89.238	Anabas_testudineus
ENSG00000198700	IPO9	95	93.826	ENSAPLG00000008676	IPO9	100	94.028	Anas_platyrhynchos
ENSG00000198700	IPO9	95	92.922	ENSACAG00000005261	IPO9	100	92.922	Anolis_carolinensis
ENSG00000198700	IPO9	100	99.808	ENSANAG00000032001	IPO9	100	99.808	Aotus_nancymaae
ENSG00000198700	IPO9	99	84.019	ENSACLG00000019807	ipo9	99	85.271	Astatotilapia_calliptera
ENSG00000198700	IPO9	99	85.303	ENSAMXG00000024731	ipo9	99	85.992	Astyanax_mexicanus
ENSG00000198700	IPO9	99	96.120	ENSBTAG00000004452	IPO9	99	96.120	Bos_taurus
ENSG00000198700	IPO9	100	100.000	ENSCJAG00000005627	IPO9	100	100.000	Callithrix_jacchus
ENSG00000198700	IPO9	95	99.193	ENSCAFG00000010649	IPO9	100	99.193	Canis_familiaris
ENSG00000198700	IPO9	100	98.665	ENSCAFG00020016229	IPO9	100	98.665	Canis_lupus_dingo
ENSG00000198700	IPO9	99	93.695	ENSCHIG00000015356	IPO9	100	93.756	Capra_hircus
ENSG00000198700	IPO9	100	99.616	ENSTSYG00000009534	IPO9	100	99.616	Carlito_syrichta
ENSG00000198700	IPO9	99	97.788	ENSCPOG00000000762	IPO9	99	97.788	Cavia_porcellus
ENSG00000198700	IPO9	100	100.000	ENSCCAG00000021455	IPO9	100	100.000	Cebus_capucinus
ENSG00000198700	IPO9	100	99.904	ENSCATG00000045312	IPO9	100	99.904	Cercocebus_atys
ENSG00000198700	IPO9	100	99.424	ENSCLAG00000015074	IPO9	100	99.424	Chinchilla_lanigera
ENSG00000198700	IPO9	100	100.000	ENSCSAG00000014031	IPO9	100	100.000	Chlorocebus_sabaeus
ENSG00000198700	IPO9	87	99.626	ENSCHOG00000013225	IPO9	87	99.626	Choloepus_hoffmanni
ENSG00000198700	IPO9	99	93.269	ENSCPBG00000018755	IPO9	95	94.255	Chrysemys_picta_bellii
ENSG00000198700	IPO9	98	48.535	ENSCING00000005342	-	99	48.340	Ciona_intestinalis
ENSG00000198700	IPO9	98	47.996	ENSCSAVG00000011013	-	98	47.703	Ciona_savignyi
ENSG00000198700	IPO9	99	93.231	ENSCANG00000031120	IPO9	99	93.231	Colobus_angolensis_palliatus
ENSG00000198700	IPO9	100	98.655	ENSCGRG00001019976	Ipo9	100	98.655	Cricetulus_griseus_chok1gshd
ENSG00000198700	IPO9	100	97.617	ENSCGRG00000013271	Ipo9	100	97.617	Cricetulus_griseus_crigri
ENSG00000198700	IPO9	100	86.316	ENSCSEG00000018787	ipo9	99	87.366	Cynoglossus_semilaevis
ENSG00000198700	IPO9	100	85.933	ENSCVAG00000008811	ipo9	99	86.906	Cyprinodon_variegatus
ENSG00000198700	IPO9	99	85.345	ENSDARG00000016753	ipo9	99	85.824	Danio_rerio
ENSG00000198700	IPO9	100	98.944	ENSDNOG00000004002	IPO9	100	98.944	Dasypus_novemcinctus
ENSG00000198700	IPO9	98	36.682	FBgn0037894	Ranbp9	98	36.625	Drosophila_melanogaster
ENSG00000198700	IPO9	99	90.183	ENSETEG00000003133	IPO9	99	90.900	Echinops_telfairi
ENSG00000198700	IPO9	66	73.110	ENSEBUG00000005745	ipo9	86	73.110	Eptatretus_burgeri
ENSG00000198700	IPO9	100	98.271	ENSEASG00005019908	IPO9	100	98.271	Equus_asinus_asinus
ENSG00000198700	IPO9	100	97.791	ENSECAG00000024368	IPO9	100	97.791	Equus_caballus
ENSG00000198700	IPO9	87	88.203	ENSELUG00000022202	ipo9	98	89.013	Esox_lucius
ENSG00000198700	IPO9	100	99.616	ENSFCAG00000000444	IPO9	100	99.616	Felis_catus
ENSG00000198700	IPO9	99	93.191	ENSFALG00000002610	IPO9	99	93.385	Ficedula_albicollis
ENSG00000198700	IPO9	100	99.424	ENSFDAG00000019466	IPO9	100	99.424	Fukomys_damarensis
ENSG00000198700	IPO9	100	86.124	ENSFHEG00000016546	ipo9	99	86.906	Fundulus_heteroclitus
ENSG00000198700	IPO9	99	85.824	ENSGMOG00000007883	ipo9	99	86.544	Gadus_morhua
ENSG00000198700	IPO9	98	94.049	ENSGALG00000000397	IPO9	99	94.083	Gallus_gallus
ENSG00000198700	IPO9	99	85.810	ENSGAFG00000014070	ipo9	99	86.712	Gambusia_affinis
ENSG00000198700	IPO9	99	85.263	ENSGACG00000006233	ipo9	99	85.963	Gasterosteus_aculeatus
ENSG00000198700	IPO9	95	94.147	ENSGAGG00000017238	IPO9	99	94.248	Gopherus_agassizii
ENSG00000198700	IPO9	100	100.000	ENSGGOG00000006787	IPO9	100	100.000	Gorilla_gorilla
ENSG00000198700	IPO9	86	88.111	ENSHBUG00000008849	ipo9	98	88.393	Haplochromis_burtoni
ENSG00000198700	IPO9	100	99.616	ENSHGLG00000011536	IPO9	100	99.616	Heterocephalus_glaber_female
ENSG00000198700	IPO9	100	99.616	ENSHGLG00100016613	IPO9	100	99.616	Heterocephalus_glaber_male
ENSG00000198700	IPO9	99	85.975	ENSIPUG00000014896	Ipo9	99	86.978	Ictalurus_punctatus
ENSG00000198700	IPO9	100	99.424	ENSSTOG00000009786	IPO9	100	99.424	Ictidomys_tridecemlineatus
ENSG00000198700	IPO9	100	99.039	ENSJJAG00000012560	Ipo9	100	99.039	Jaculus_jaculus
ENSG00000198700	IPO9	100	83.556	ENSKMAG00000013352	ipo9	99	84.593	Kryptolebias_marmoratus
ENSG00000198700	IPO9	99	87.294	ENSLBEG00000012471	ipo9	99	87.306	Labrus_bergylta
ENSG00000198700	IPO9	99	85.577	ENSLACG00000012842	IPO9	98	86.267	Latimeria_chalumnae
ENSG00000198700	IPO9	99	87.731	ENSLOCG00000010108	ipo9	98	87.743	Lepisosteus_oculatus
ENSG00000198700	IPO9	100	97.695	ENSLAFG00000012565	IPO9	100	97.695	Loxodonta_africana
ENSG00000198700	IPO9	100	100.000	ENSMFAG00000035917	IPO9	100	100.000	Macaca_fascicularis
ENSG00000198700	IPO9	100	98.951	ENSMMUG00000001916	IPO9	100	98.951	Macaca_mulatta
ENSG00000198700	IPO9	100	100.000	ENSMNEG00000043396	IPO9	100	100.000	Macaca_nemestrina
ENSG00000198700	IPO9	100	98.951	ENSMLEG00000030171	IPO9	100	98.951	Mandrillus_leucophaeus
ENSG00000198700	IPO9	87	88.411	ENSMAMG00000008798	ipo9	97	89.238	Mastacembelus_armatus
ENSG00000198700	IPO9	99	84.019	ENSMZEG00005005610	ipo9	99	85.271	Maylandia_zebra
ENSG00000198700	IPO9	95	93.367	ENSMGAG00000001445	IPO9	100	93.568	Meleagris_gallopavo
ENSG00000198700	IPO9	100	97.891	ENSMAUG00000020318	Ipo9	100	97.891	Mesocricetus_auratus
ENSG00000198700	IPO9	100	99.712	ENSMICG00000009250	IPO9	100	99.712	Microcebus_murinus
ENSG00000198700	IPO9	100	98.751	ENSMOCG00000022988	Ipo9	100	98.751	Microtus_ochrogaster
ENSG00000198700	IPO9	86	88.132	ENSMMOG00000006199	ipo9	98	88.667	Mola_mola
ENSG00000198700	IPO9	99	96.821	ENSMODG00000000485	IPO9	99	96.821	Monodelphis_domestica
ENSG00000198700	IPO9	100	83.317	ENSMALG00000010742	ipo9	99	82.517	Monopterus_albus
ENSG00000198700	IPO9	99	94.767	MGP_CAROLIEiJ_G0014639	Ipo9	99	94.767	Mus_caroli
ENSG00000198700	IPO9	100	98.847	ENSMUSG00000041879	Ipo9	100	98.847	Mus_musculus
ENSG00000198700	IPO9	100	99.039	MGP_PahariEiJ_G0027875	Ipo9	100	99.039	Mus_pahari
ENSG00000198700	IPO9	100	98.847	MGP_SPRETEiJ_G0015446	Ipo9	100	98.847	Mus_spretus
ENSG00000198700	IPO9	100	99.424	ENSMPUG00000010874	IPO9	94	99.424	Mustela_putorius_furo
ENSG00000198700	IPO9	91	93.606	ENSMLUG00000006640	IPO9	100	93.816	Myotis_lucifugus
ENSG00000198700	IPO9	100	99.232	ENSNGAG00000014956	Ipo9	100	99.232	Nannospalax_galili
ENSG00000198700	IPO9	65	90.796	ENSNBRG00000005251	ipo9	85	91.457	Neolamprologus_brichardi
ENSG00000198700	IPO9	100	99.904	ENSNLEG00000018086	IPO9	100	99.904	Nomascus_leucogenys
ENSG00000198700	IPO9	78	95.261	ENSMEUG00000007152	IPO9	85	95.261	Notamacropus_eugenii
ENSG00000198700	IPO9	100	99.328	ENSODEG00000011377	IPO9	100	99.328	Octodon_degus
ENSG00000198700	IPO9	99	86.699	ENSONIG00000011495	ipo9	99	87.380	Oreochromis_niloticus
ENSG00000198700	IPO9	95	95.358	ENSOANG00000009358	IPO9	100	95.560	Ornithorhynchus_anatinus
ENSG00000198700	IPO9	100	99.424	ENSOCUG00000007477	IPO9	91	99.424	Oryctolagus_cuniculus
ENSG00000198700	IPO9	99	84.276	ENSORLG00000005758	ipo9	99	85.160	Oryzias_latipes
ENSG00000198700	IPO9	100	84.402	ENSORLG00020016512	ipo9	99	85.160	Oryzias_latipes_hni
ENSG00000198700	IPO9	100	84.211	ENSORLG00015012256	ipo9	99	84.966	Oryzias_latipes_hsok
ENSG00000198700	IPO9	100	84.226	ENSOMEG00000017601	ipo9	99	85.078	Oryzias_melastigma
ENSG00000198700	IPO9	100	99.808	ENSOGAG00000006162	IPO9	100	99.808	Otolemur_garnettii
ENSG00000198700	IPO9	95	92.315	ENSOARG00000019086	IPO9	100	92.315	Ovis_aries
ENSG00000198700	IPO9	100	100.000	ENSPPAG00000037356	IPO9	100	100.000	Pan_paniscus
ENSG00000198700	IPO9	100	99.616	ENSPPRG00000005675	IPO9	100	99.616	Panthera_pardus
ENSG00000198700	IPO9	97	99.604	ENSPTIG00000009708	IPO9	99	99.604	Panthera_tigris_altaica
ENSG00000198700	IPO9	100	100.000	ENSPTRG00000023652	IPO9	100	100.000	Pan_troglodytes
ENSG00000198700	IPO9	100	97.619	ENSPANG00000026214	IPO9	100	97.619	Papio_anubis
ENSG00000198700	IPO9	99	86.299	ENSPKIG00000017281	ipo9	99	87.175	Paramormyrops_kingsleyae
ENSG00000198700	IPO9	85	89.101	ENSPMGG00000008544	ipo9	98	89.113	Periophthalmus_magnuspinnatus
ENSG00000198700	IPO9	100	98.367	ENSPEMG00000017658	Ipo9	100	98.367	Peromyscus_maniculatus_bairdii
ENSG00000198700	IPO9	99	96.625	ENSPCIG00000030448	IPO9	99	96.625	Phascolarctos_cinereus
ENSG00000198700	IPO9	99	86.002	ENSPFOG00000004346	ipo9	99	86.712	Poecilia_formosa
ENSG00000198700	IPO9	99	86.002	ENSPLAG00000012867	ipo9	99	86.712	Poecilia_latipinna
ENSG00000198700	IPO9	99	83.462	ENSPMEG00000021436	ipo9	99	83.949	Poecilia_mexicana
ENSG00000198700	IPO9	99	84.564	ENSPREG00000008970	ipo9	99	85.257	Poecilia_reticulata
ENSG00000198700	IPO9	100	98.854	ENSPCOG00000014001	IPO9	100	98.854	Propithecus_coquereli
ENSG00000198700	IPO9	86	88.222	ENSPNYG00000013180	ipo9	98	88.504	Pundamilia_nyererei
ENSG00000198700	IPO9	99	84.038	ENSPNAG00000015428	ipo9	99	85.214	Pygocentrus_nattereri
ENSG00000198700	IPO9	100	99.039	ENSRNOG00000007418	Ipo9	100	99.039	Rattus_norvegicus
ENSG00000198700	IPO9	100	100.000	ENSRBIG00000038277	IPO9	100	100.000	Rhinopithecus_bieti
ENSG00000198700	IPO9	100	100.000	ENSRROG00000045165	IPO9	100	100.000	Rhinopithecus_roxellana
ENSG00000198700	IPO9	100	98.079	ENSSBOG00000023990	IPO9	100	98.079	Saimiri_boliviensis_boliviensis
ENSG00000198700	IPO9	99	93.834	ENSSHAG00000010437	IPO9	99	94.180	Sarcophilus_harrisii
ENSG00000198700	IPO9	99	83.652	ENSSFOG00015018530	ipo9	99	83.908	Scleropages_formosus
ENSG00000198700	IPO9	95	86.874	ENSSMAG00000011675	ipo9	99	86.874	Scophthalmus_maximus
ENSG00000198700	IPO9	100	87.285	ENSSDUG00000019692	ipo9	99	88.372	Seriola_dumerili
ENSG00000198700	IPO9	100	87.202	ENSSLDG00000017170	ipo9	99	88.093	Seriola_lalandi_dorsalis
ENSG00000198700	IPO9	76	90.701	ENSSARG00000005420	IPO9	80	90.701	Sorex_araneus
ENSG00000198700	IPO9	99	89.231	ENSSPUG00000012890	IPO9	99	90.610	Sphenodon_punctatus
ENSG00000198700	IPO9	100	87.094	ENSSPAG00000015136	ipo9	99	88.178	Stegastes_partitus
ENSG00000198700	IPO9	100	96.542	ENSSSCG00000039843	IPO9	100	96.542	Sus_scrofa
ENSG00000198700	IPO9	99	86.015	ENSTRUG00000012941	ipo9	97	86.809	Takifugu_rubripes
ENSG00000198700	IPO9	100	86.533	ENSTNIG00000007044	ipo9	99	87.222	Tetraodon_nigroviridis
ENSG00000198700	IPO9	99	94.083	ENSTBEG00000010254	IPO9	99	94.083	Tupaia_belangeri
ENSG00000198700	IPO9	96	93.380	ENSTTRG00000005969	IPO9	100	93.380	Tursiops_truncatus
ENSG00000198700	IPO9	99	98.279	ENSUMAG00000003122	IPO9	99	98.279	Ursus_maritimus
ENSG00000198700	IPO9	53	99.091	ENSVPAG00000010575	-	55	99.091	Vicugna_pacos
ENSG00000198700	IPO9	95	99.696	ENSVVUG00000006283	IPO9	99	99.197	Vulpes_vulpes
ENSG00000198700	IPO9	99	86.802	ENSXETG00000007974	ipo9	99	86.705	Xenopus_tropicalis
ENSG00000198700	IPO9	100	82.471	ENSXCOG00000013891	ipo9	98	84.144	Xiphophorus_couchianus
ENSG00000198700	IPO9	99	86.098	ENSXMAG00000006013	ipo9	99	86.809	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	11823430.15282309.	IPI	Function
GO:0005635	nuclear envelope	21873635.	IBA	Component
GO:0005737	cytoplasm	11823430.	IDA	Component
GO:0005829	cytosol	21873635.	IBA	Component
GO:0006606	protein import into nucleus	21873635.	IBA	Process
GO:0006606	protein import into nucleus	11823430.	IDA	Process
GO:0008536	Ran GTPase binding	-	IEA	Function
GO:0008565	protein transporter activity	21873635.	IBA	Function
GO:0008565	protein transporter activity	11823430.	IDA	Function
GO:0016020	membrane	19946888.	HDA	Component
GO:0042393	histone binding	-	ISS	Function