EuRBPDB

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000198730 (Gene tree)
Gene ID: 9646
Gene Symbol: CTR9
Alias: KIAA0155|TSBP|p150TSP|SH2BP1
Full Name: CTR9 homolog, Paf1/RNA polymerase II complex component
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 50,639 bases
Position: chr11:10,750,987-10,801,625
Accession: 16850
RBP type: non-canonical RBP
Summary: The protein encoded by this gene is a component of the PAF1 complex, which associates with RNA polymerase II and functions in transcriptional regulation and elongation. This complex also plays a role in the modification of histones. [provided by RefSeq, Oct 2016]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
22532828	Depletion of trypanosome CTR9 leads to gene expression defects.	PLoS One	2012	Ouna BA	doi: 10.1371/journal.pone.0034256

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000532365	CTR9-206	577	-	ENSP00000493551	52 (aa)	-	A0A2R8Y3S3
ENST00000524523	CTR9-202	902	-	ENSP00000431458	300 (aa)	-	H0YCE8
ENST00000529355	CTR9-204	1146	-	-	- (aa)	-	-
ENST00000361367	CTR9-201	4586	-	ENSP00000355013	1173 (aa)	-	Q6PD62
ENST00000526874	CTR9-203	565	-	-	- (aa)	-	-
ENST00000529898	CTR9-205	594	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000198730's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000198730	Coronary Disease	3.0010000E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000198730's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000198730	CTR9	100	97.532	ENSMUSG00000005609	Ctr9	100	97.532	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	-	ISS	Process
GO:0000993	RNA polymerase II complex binding	21873635.	IBA	Function
GO:0001711	endodermal cell fate commitment	-	ISS	Process
GO:0001826	inner cell mass cell differentiation	-	IEA	Process
GO:0001829	trophectodermal cell differentiation	-	IEA	Process
GO:0001832	blastocyst growth	-	IEA	Process
GO:0001835	blastocyst hatching	-	IEA	Process
GO:0005515	protein binding	15923622.16024656.19136632.19410543.20178742.20541477.26496610.29774127.	IPI	Function
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0006366	transcription by RNA polymerase II	-	TAS	Process
GO:0006368	transcription elongation from RNA polymerase II promoter	-	TAS	Process
GO:0007259	JAK-STAT cascade	-	ISS	Process
GO:0010390	histone monoubiquitination	16307923.	IDA	Process
GO:0016055	Wnt signaling pathway	-	IEA	Process
GO:0016567	protein ubiquitination	-	TAS	Process
GO:0016593	Cdc73/Paf1 complex	21873635.	IBA	Component
GO:0016593	Cdc73/Paf1 complex	16307923.20178742.	IDA	Component
GO:0016607	nuclear speck	-	IEA	Component
GO:0019827	stem cell population maintenance	19345177.	IDA	Process
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	20178742.	IDA	Process
GO:0033523	histone H2B ubiquitination	16307923.	IDA	Process
GO:0035327	transcriptionally active chromatin	-	ISS	Component
GO:0042169	SH2 domain binding	-	IEA	Function
GO:0045638	negative regulation of myeloid cell differentiation	20541477.	IDA	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	20178742.	IDA	Process
GO:0051569	regulation of histone H3-K4 methylation	21873635.	IBA	Process
GO:0051571	positive regulation of histone H3-K4 methylation	16024656.	IMP	Process
GO:0070102	interleukin-6-mediated signaling pathway	-	ISS	Process
GO:0071222	cellular response to lipopolysaccharide	-	ISS	Process
GO:0080182	histone H3-K4 trimethylation	16024656.	IMP	Process
GO:1900364	negative regulation of mRNA polyadenylation	19575011.	IMP	Process
GO:2000653	regulation of genetic imprinting	-	IEA	Process
GO:2001162	positive regulation of histone H3-K79 methylation	16024656.	IMP	Process
GO:2001168	positive regulation of histone H2B ubiquitination	19575011.	IMP	Process