EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000198858 (Gene tree)
Gene ID: 91300
Gene Symbol: R3HDM4
Alias: MGC16353|C19orf22
Full Name: R3H domain containing 4
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 16,743 bases
Position: chr19:896,503-913,245
Accession: 28270
RBP type: canonical RBP
Summary: R3HDM4 (R3H Domain Containing 4) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000464744	R3H	PF01424.22	3.7e-06	1	1
ENSP00000355385	R3H	PF01424.22	4.1e-06	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000591829	R3HDM4-207	823	-	-	- (aa)	-	-
ENST00000590454	R3HDM4-206	1006	-	ENSP00000468026	45 (aa)	-	K7ER32
ENST00000626716	R3HDM4-208	138	-	ENSP00000486092	45 (aa)	-	K7ER32
ENST00000589445	R3HDM4-205	705	-	-	- (aa)	-	-
ENST00000589428	R3HDM4-204	1704	-	ENSP00000466823	97 (aa)	-	K7EN78
ENST00000587975	R3HDM4-203	1765	-	ENSP00000464744	247 (aa)	-	K7EIG9
ENST00000586080	R3HDM4-202	537	-	-	- (aa)	-	-
ENST00000361574	R3HDM4-201	1815	XM_011528416	ENSP00000355385	268 (aa)	XP_011526718	Q96D70

Gene Model

Click here to download ENSG00000198858's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000198858	rs12985393	19	898288	T	High light scatter reticulocyte count	27863252	[0.018-0.033] unit decrease	0.02550716	EFO_0007986
ENSG00000198858	rs111932385	19	906510	A	High light scatter reticulocyte count	27863252	[0.12-0.18] unit increase	0.1465017	EFO_0007986
ENSG00000198858	rs1683587	19	913048	C	High light scatter reticulocyte count	27863252	[0.045-0.06] unit decrease	0.05288179	EFO_0007986
ENSG00000198858	rs12985393	19	898288	T	High light scatter reticulocyte percentage of red cells	27863252	[0.018-0.034] unit decrease	0.02613904	EFO_0007986
ENSG00000198858	rs111932385	19	906510	A	High light scatter reticulocyte percentage of red cells	27863252	[0.12-0.18] unit increase	0.1531547	EFO_0007986
ENSG00000198858	rs1683587	19	913048	C	High light scatter reticulocyte percentage of red cells	27863252	[0.045-0.06] unit decrease	0.05235026	EFO_0007986
ENSG00000198858	rs12985393	19	898288	T	Reticulocyte count	27863252	[0.017-0.033] unit decrease	0.02495241	EFO_0007986
ENSG00000198858	rs111932385	19	906510	A	Reticulocyte count	27863252	[0.091-0.151] unit increase	0.1211533	EFO_0007986
ENSG00000198858	rs1683587	19	913048	C	Reticulocyte count	27863252	[0.037-0.052] unit decrease	0.04477088	EFO_0007986
ENSG00000198858	rs111932385	19	906510	A	Reticulocyte fraction of red cells	27863252	[0.1-0.16] unit increase	0.1330732	EFO_0007986
ENSG00000198858	rs12985393	19	898288	T	Reticulocyte fraction of red cells	27863252	[0.018-0.034] unit decrease	0.02618045	EFO_0007986
ENSG00000198858	rs1683587	19	913048	C	Reticulocyte fraction of red cells	27863252	[0.037-0.052] unit decrease	0.04448547	EFO_0007986
ENSG00000198858	rs111932385	19	906510	A	Immature fraction of reticulocytes	27863252	[0.1-0.16] unit increase	0.1314682	EFO_0007986
ENSG00000198858	rs1683587	19	913048	C	Immature fraction of reticulocytes	27863252	[0.041-0.056] unit decrease	0.04872839	EFO_0007986
ENSG00000198858	rs111607343	19	897855	G	Monokine induced by gamma interferon levels	27989323	[0.3-0.74] SD units increase	0.521	EFO_0008236

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000198858's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000198858	R3HDM4	91	92.623	ENSAMEG00000003001	R3HDM4	100	92.623	Ailuropoda_melanoleuca
ENSG00000198858	R3HDM4	90	58.036	ENSACIG00000004672	r3hdm4	91	57.143	Amphilophus_citrinellus
ENSG00000198858	R3HDM4	89	53.846	ENSATEG00000015913	r3hdm4	91	54.468	Anabas_testudineus
ENSG00000198858	R3HDM4	91	97.119	ENSANAG00000029748	R3HDM4	100	97.119	Aotus_nancymaae
ENSG00000198858	R3HDM4	94	94.444	ENSBTAG00000046406	R3HDM4	100	91.912	Bos_taurus
ENSG00000198858	R3HDM4	94	95.618	ENSCJAG00000020114	R3HDM4	93	95.618	Callithrix_jacchus
ENSG00000198858	R3HDM4	100	90.809	ENSCAFG00000019665	R3HDM4	100	90.809	Canis_familiaris
ENSG00000198858	R3HDM4	100	90.441	ENSCAFG00020016880	R3HDM4	100	90.441	Canis_lupus_dingo
ENSG00000198858	R3HDM4	100	92.279	ENSCHIG00000020110	R3HDM4	100	92.279	Capra_hircus
ENSG00000198858	R3HDM4	91	96.296	ENSCCAG00000019955	R3HDM4	88	96.296	Cebus_capucinus
ENSG00000198858	R3HDM4	100	97.037	ENSCATG00000037269	R3HDM4	100	97.037	Cercocebus_atys
ENSG00000198858	R3HDM4	90	94.170	ENSCLAG00000007094	R3HDM4	100	93.033	Chinchilla_lanigera
ENSG00000198858	R3HDM4	100	97.388	ENSCSAG00000012574	R3HDM4	100	97.388	Chlorocebus_sabaeus
ENSG00000198858	R3HDM4	97	68.340	ENSCPBG00000009805	R3HDM4	98	68.340	Chrysemys_picta_bellii
ENSG00000198858	R3HDM4	91	97.143	ENSCANG00000040439	R3HDM4	86	97.143	Colobus_angolensis_palliatus
ENSG00000198858	R3HDM4	99	85.821	ENSCGRG00001021650	R3hdm4	100	86.194	Cricetulus_griseus_chok1gshd
ENSG00000198858	R3HDM4	99	85.821	ENSCGRG00000013169	R3hdm4	100	86.194	Cricetulus_griseus_crigri
ENSG00000198858	R3HDM4	90	55.357	ENSCSEG00000018211	r3hdm4	91	54.202	Cynoglossus_semilaevis
ENSG00000198858	R3HDM4	93	56.000	ENSCVAG00000017127	r3hdm4	93	56.000	Cyprinodon_variegatus
ENSG00000198858	R3HDM4	97	88.550	ENSDORG00000006605	R3hdm4	100	92.245	Dipodomys_ordii
ENSG00000198858	R3HDM4	99	87.687	ENSEASG00005021556	R3HDM4	89	94.262	Equus_asinus_asinus
ENSG00000198858	R3HDM4	93	93.952	ENSECAG00000000003	R3HDM4	100	92.251	Equus_caballus
ENSG00000198858	R3HDM4	100	91.852	ENSFCAG00000042437	R3HDM4	100	91.852	Felis_catus
ENSG00000198858	R3HDM4	90	71.749	ENSFALG00000013938	R3HDM4	100	69.547	Ficedula_albicollis
ENSG00000198858	R3HDM4	91	91.429	ENSFDAG00000017040	R3HDM4	100	91.429	Fukomys_damarensis
ENSG00000198858	R3HDM4	93	56.000	ENSFHEG00000017636	r3hdm4	93	56.000	Fundulus_heteroclitus
ENSG00000198858	R3HDM4	94	50.855	ENSGMOG00000001231	r3hdm4	97	52.521	Gadus_morhua
ENSG00000198858	R3HDM4	94	66.023	ENSGALG00000001998	R3HDM4	98	66.023	Gallus_gallus
ENSG00000198858	R3HDM4	100	54.647	ENSGAFG00000004173	r3hdm4	100	54.647	Gambusia_affinis
ENSG00000198858	R3HDM4	97	67.568	ENSGAGG00000019698	R3HDM4	98	67.568	Gopherus_agassizii
ENSG00000198858	R3HDM4	99	94.361	ENSGGOG00000008040	R3HDM4	100	99.180	Gorilla_gorilla
ENSG00000198858	R3HDM4	90	56.889	ENSHBUG00000014810	r3hdm4	91	57.322	Haplochromis_burtoni
ENSG00000198858	R3HDM4	100	88.848	ENSHGLG00000016194	R3HDM4	100	89.219	Heterocephalus_glaber_female
ENSG00000198858	R3HDM4	89	57.466	ENSHCOG00000008422	r3hdm4	91	55.745	Hippocampus_comes
ENSG00000198858	R3HDM4	90	57.589	ENSIPUG00000006716	r3hdm4	91	56.723	Ictalurus_punctatus
ENSG00000198858	R3HDM4	98	86.122	ENSSTOG00000023015	R3HDM4	100	91.393	Ictidomys_tridecemlineatus
ENSG00000198858	R3HDM4	99	89.552	ENSJJAG00000012475	R3hdm4	100	89.552	Jaculus_jaculus
ENSG00000198858	R3HDM4	97	55.602	ENSKMAG00000005853	r3hdm4	91	56.485	Kryptolebias_marmoratus
ENSG00000198858	R3HDM4	90	56.250	ENSLBEG00000000730	r3hdm4	91	55.462	Labrus_bergylta
ENSG00000198858	R3HDM4	90	64.126	ENSLACG00000016445	R3HDM4	94	61.633	Latimeria_chalumnae
ENSG00000198858	R3HDM4	96	57.025	ENSLOCG00000002423	r3hdm4	91	58.159	Lepisosteus_oculatus
ENSG00000198858	R3HDM4	94	91.270	ENSLAFG00000017796	R3HDM4	97	91.270	Loxodonta_africana
ENSG00000198858	R3HDM4	100	97.761	ENSMFAG00000044131	R3HDM4	100	97.761	Macaca_fascicularis
ENSG00000198858	R3HDM4	100	97.976	ENSMMUG00000009682	R3HDM4	100	97.976	Macaca_mulatta
ENSG00000198858	R3HDM4	91	97.951	ENSMNEG00000044115	R3HDM4	99	97.951	Macaca_nemestrina
ENSG00000198858	R3HDM4	91	96.341	ENSMLEG00000035693	R3HDM4	91	96.341	Mandrillus_leucophaeus
ENSG00000198858	R3HDM4	77	59.375	ENSMAMG00000005652	r3hdm4	82	58.252	Mastacembelus_armatus
ENSG00000198858	R3HDM4	99	84.701	ENSMAUG00000010611	R3hdm4	100	85.075	Mesocricetus_auratus
ENSG00000198858	R3HDM4	100	93.704	ENSMICG00000010124	R3HDM4	100	93.704	Microcebus_murinus
ENSG00000198858	R3HDM4	99	84.270	ENSMOCG00000002646	R3hdm4	100	84.644	Microtus_ochrogaster
ENSG00000198858	R3HDM4	90	56.696	ENSMMOG00000008253	r3hdm4	92	55.462	Mola_mola
ENSG00000198858	R3HDM4	95	66.809	ENSMODG00000005698	R3HDM4	100	66.810	Monodelphis_domestica
ENSG00000198858	R3HDM4	90	56.250	ENSMALG00000018856	r3hdm4	91	55.042	Monopterus_albus
ENSG00000198858	R3HDM4	99	83.895	MGP_CAROLIEiJ_G0015551	R3hdm4	100	85.019	Mus_caroli
ENSG00000198858	R3HDM4	99	83.895	ENSMUSG00000035781	R3hdm4	100	85.019	Mus_musculus
ENSG00000198858	R3HDM4	99	84.644	MGP_PahariEiJ_G0030964	R3hdm4	100	85.768	Mus_pahari
ENSG00000198858	R3HDM4	99	83.895	MGP_SPRETEiJ_G0016369	-	84	85.019	Mus_spretus
ENSG00000198858	R3HDM4	98	88.934	ENSMPUG00000009394	R3HDM4	96	89.189	Mustela_putorius_furo
ENSG00000198858	R3HDM4	90	56.444	ENSNBRG00000004438	r3hdm4	91	56.904	Neolamprologus_brichardi
ENSG00000198858	R3HDM4	85	96.279	ENSNLEG00000001022	R3HDM4	100	96.537	Nomascus_leucogenys
ENSG00000198858	R3HDM4	90	67.411	ENSMEUG00000011020	R3HDM4	99	66.667	Notamacropus_eugenii
ENSG00000198858	R3HDM4	100	90.335	ENSODEG00000011745	R3HDM4	100	90.335	Octodon_degus
ENSG00000198858	R3HDM4	90	56.444	ENSONIG00000012675	r3hdm4	84	56.904	Oreochromis_niloticus
ENSG00000198858	R3HDM4	90	58.667	ENSOMEG00000003005	r3hdm4	91	57.322	Oryzias_melastigma
ENSG00000198858	R3HDM4	90	95.045	ENSOGAG00000025656	R3HDM4	92	93.827	Otolemur_garnettii
ENSG00000198858	R3HDM4	91	95.082	ENSOARG00000009945	R3HDM4	100	95.082	Ovis_aries
ENSG00000198858	R3HDM4	99	94.737	ENSPPAG00000042371	R3HDM4	100	99.590	Pan_paniscus
ENSG00000198858	R3HDM4	82	75.676	ENSPTRG00000049897	-	100	99.107	Pan_troglodytes
ENSG00000198858	R3HDM4	100	97.761	ENSPANG00000015203	R3HDM4	100	97.761	Papio_anubis
ENSG00000198858	R3HDM4	90	56.250	ENSPKIG00000007421	r3hdm4	88	55.745	Paramormyrops_kingsleyae
ENSG00000198858	R3HDM4	94	52.964	ENSPMGG00000020467	r3hdm4	94	52.964	Periophthalmus_magnuspinnatus
ENSG00000198858	R3HDM4	90	90.541	ENSPEMG00000008365	Tmem259	100	89.300	Peromyscus_maniculatus_bairdii
ENSG00000198858	R3HDM4	97	55.417	ENSPFOG00000003199	r3hdm4	93	55.823	Poecilia_formosa
ENSG00000198858	R3HDM4	97	55.000	ENSPMEG00000014183	r3hdm4	93	55.422	Poecilia_mexicana
ENSG00000198858	R3HDM4	97	55.833	ENSPREG00000010709	r3hdm4	93	56.225	Poecilia_reticulata
ENSG00000198858	R3HDM4	100	94.776	ENSPPYG00000009297	R3HDM4	100	94.776	Pongo_abelii
ENSG00000198858	R3HDM4	61	92.763	ENSPCAG00000010997	R3HDM4	56	92.763	Procavia_capensis
ENSG00000198858	R3HDM4	100	93.704	ENSPCOG00000016785	R3HDM4	100	93.704	Propithecus_coquereli
ENSG00000198858	R3HDM4	90	56.889	ENSPNYG00000017489	r3hdm4	91	57.322	Pundamilia_nyererei
ENSG00000198858	R3HDM4	99	84.270	ENSRNOG00000011489	R3hdm4	100	84.644	Rattus_norvegicus
ENSG00000198858	R3HDM4	91	97.951	ENSRROG00000028842	R3HDM4	91	97.951	Rhinopithecus_roxellana
ENSG00000198858	R3HDM4	91	93.522	ENSSBOG00000019298	R3HDM4	72	94.332	Saimiri_boliviensis_boliviensis
ENSG00000198858	R3HDM4	59	71.233	ENSSHAG00000003036	-	100	71.233	Sarcophilus_harrisii
ENSG00000198858	R3HDM4	90	57.143	ENSSFOG00015020574	r3hdm4	87	56.303	Scleropages_formosus
ENSG00000198858	R3HDM4	90	57.778	ENSSMAG00000021090	r3hdm4	68	56.904	Scophthalmus_maximus
ENSG00000198858	R3HDM4	90	58.667	ENSSDUG00000008488	r3hdm4	91	57.741	Seriola_dumerili
ENSG00000198858	R3HDM4	90	58.667	ENSSLDG00000025328	r3hdm4	91	57.741	Seriola_lalandi_dorsalis
ENSG00000198858	R3HDM4	97	68.313	ENSSPUG00000005434	R3HDM4	93	71.250	Sphenodon_punctatus
ENSG00000198858	R3HDM4	89	55.405	ENSSPAG00000002562	r3hdm4	90	55.085	Stegastes_partitus
ENSG00000198858	R3HDM4	100	92.279	ENSSSCG00000013419	R3HDM4	100	92.279	Sus_scrofa
ENSG00000198858	R3HDM4	77	65.625	ENSTGUG00000000663	R3HDM4	100	64.593	Taeniopygia_guttata
ENSG00000198858	R3HDM4	91	91.803	ENSTTRG00000001470	R3HDM4	100	92.213	Tursiops_truncatus
ENSG00000198858	R3HDM4	90	93.722	ENSUAMG00000005751	R3HDM4	100	93.722	Ursus_americanus
ENSG00000198858	R3HDM4	100	91.544	ENSVVUG00000022685	R3HDM4	100	91.544	Vulpes_vulpes
ENSG00000198858	R3HDM4	94	45.850	ENSXETG00000033624	R3HDM4	97	45.850	Xenopus_tropicalis
ENSG00000198858	R3HDM4	100	53.704	ENSXCOG00000005127	r3hdm4	100	53.704	Xiphophorus_couchianus
ENSG00000198858	R3HDM4	100	53.903	ENSXMAG00000022875	r3hdm4	100	53.903	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003676	nucleic acid binding	-	IEA	Function
GO:0005634	nucleus	-	IEA	Component