EuRBPDB

Description

Ensembl ID: ENSG00000198862 (Gene tree)
Gene ID: 26046
Gene Symbol: LTN1
Alias: KIAA0714|FLJ11053|LISTERIN|C21orf98|C21orf10|ZNF294|RNF160
Full Name: listerin E3 ubiquitin protein ligase 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 64,813 bases
Position: chr21:28,928,144-28,992,956
Accession: 13082
RBP type: non-canonical RBP
Summary: Like most RING finger proteins, LTN1 functions as an E3 ubiquitin ligase (Chu et al., 2009 [PubMed 19196968]).[supplied by OMIM, Nov 2010]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000614971	LTN1-207	7756	-	ENSP00000478783	1812 (aa)	-	O94822
ENST00000361371	LTN1-201	7685	XM_017028316	ENSP00000354977	1766 (aa)	XP_016883805	O94822
ENST00000475344	LTN1-204	696	-	-	- (aa)	-	-
ENST00000486427	LTN1-206	539	-	-	- (aa)	-	-
ENST00000389195	LTN1-203	2714	XM_006723987	ENSP00000373847	813 (aa)	XP_006724050	H7BYG8
ENST00000389194	LTN1-202	7749	-	ENSP00000373846	1812 (aa)	-	O94822
ENST00000483326	LTN1-205	1753	-	ENSP00000474690	366 (aa)	-	S4R3T2

Gene Model

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000198862	rs57646126	21	28959613	?	Initial pursuit acceleration in psychotic disorders	29064472			EFO_0000692\|EFO_0008434\|EFO_0000289\|EFO_0005411

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	21903422.	IPI	Function
GO:0005829	cytosol	21873635.	IBA	Component
GO:0008270	zinc ion binding	-	IEA	Function
GO:0043023	ribosomal large subunit binding	21873635.	IBA	Function
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	21873635.	IBA	Process
GO:0051865	protein autoubiquitination	-	IEA	Process
GO:0061630	ubiquitin protein ligase activity	21873635.	IBA	Function
GO:0072344	rescue of stalled ribosome	21873635.	IBA	Process
GO:1990112	RQC complex	21873635.	IBA	Component
GO:1990116	ribosome-associated ubiquitin-dependent protein catabolic process	21873635.	IBA	Process