EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000198917 (Gene tree)
Gene ID: 51490
Gene Symbol: SPOUT1
Alias: HSPC109|CENP-32|C9orf114
Full Name: SPOUT domain containing methyltransferase 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 10,197 bases
Position: chr9:128,819,651-128,829,847
Accession: 26933
RBP type: canonical RBP
Summary: (SPOUT Domain Containing Methyltransferase 1) is a Protein Coding gene.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000354812	Methyltrn_RNA_3	PF02598.17	2.5e-109	1	1
ENSP00000473640	Methyltrn_RNA_3	PF02598.17	3.9e-14	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000361256	SPOUT1-201	4286	XM_017014804	ENSP00000354812	376 (aa)	XP_016870293	Q5T280
ENST00000466556	SPOUT1-202	926	-	-	- (aa)	-	-
ENST00000480366	SPOUT1-205	661	-	-	- (aa)	-	-
ENST00000467396	SPOUT1-203	451	-	-	- (aa)	-	-
ENST00000467582	SPOUT1-204	898	-	ENSP00000473640	87 (aa)	-	R4GNG4

Gene Model

Click here to download ENSG00000198917's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000198917's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000198917	SPOUT1	93	68.481	ENSAPOG00000021073	spout1	91	67.908	Acanthochromis_polyacanthus
ENSG00000198917	SPOUT1	99	94.118	ENSAMEG00000015808	SPOUT1	99	94.118	Ailuropoda_melanoleuca
ENSG00000198917	SPOUT1	90	70.414	ENSACIG00000001649	spout1	88	74.342	Amphilophus_citrinellus
ENSG00000198917	SPOUT1	93	67.908	ENSAOCG00000001097	spout1	79	73.064	Amphiprion_ocellaris
ENSG00000198917	SPOUT1	93	67.622	ENSAPEG00000022391	spout1	77	73.720	Amphiprion_percula
ENSG00000198917	SPOUT1	93	68.857	ENSATEG00000012696	spout1	92	68.661	Anabas_testudineus
ENSG00000198917	SPOUT1	80	77.632	ENSAPLG00000005094	SPOUT1	88	77.632	Anas_platyrhynchos
ENSG00000198917	SPOUT1	80	77.815	ENSACAG00000000010	SPOUT1	93	77.558	Anolis_carolinensis
ENSG00000198917	SPOUT1	100	97.074	ENSANAG00000036350	SPOUT1	100	97.074	Aotus_nancymaae
ENSG00000198917	SPOUT1	98	68.478	ENSACLG00000027828	spout1	97	67.935	Astatotilapia_calliptera
ENSG00000198917	SPOUT1	93	69.341	ENSAMXG00000014331	spout1	78	76.351	Astyanax_mexicanus
ENSG00000198917	SPOUT1	99	94.385	ENSBTAG00000012485	SPOUT1	99	94.385	Bos_taurus
ENSG00000198917	SPOUT1	91	39.118	WBGene00015160	B0361.6	82	40.694	Caenorhabditis_elegans
ENSG00000198917	SPOUT1	100	95.745	ENSCJAG00000020221	SPOUT1	100	95.745	Callithrix_jacchus
ENSG00000198917	SPOUT1	100	92.553	ENSCAFG00000020032	SPOUT1	100	92.553	Canis_familiaris
ENSG00000198917	SPOUT1	100	92.553	ENSCAFG00020022980	SPOUT1	100	92.553	Canis_lupus_dingo
ENSG00000198917	SPOUT1	90	93.491	ENSCHIG00000010025	SPOUT1	92	93.921	Capra_hircus
ENSG00000198917	SPOUT1	100	91.755	ENSTSYG00000030758	SPOUT1	100	91.755	Carlito_syrichta
ENSG00000198917	SPOUT1	98	90.489	ENSCAPG00000008073	SPOUT1	100	90.489	Cavia_aperea
ENSG00000198917	SPOUT1	100	90.741	ENSCPOG00000004710	SPOUT1	100	90.741	Cavia_porcellus
ENSG00000198917	SPOUT1	100	96.277	ENSCCAG00000037842	SPOUT1	100	96.277	Cebus_capucinus
ENSG00000198917	SPOUT1	99	97.067	ENSCATG00000042611	SPOUT1	99	97.067	Cercocebus_atys
ENSG00000198917	SPOUT1	94	87.606	ENSCLAG00000006487	SPOUT1	90	87.606	Chinchilla_lanigera
ENSG00000198917	SPOUT1	89	68.060	ENSCPBG00000023348	SPOUT1	97	70.724	Chrysemys_picta_bellii
ENSG00000198917	SPOUT1	90	59.827	ENSCING00000008293	-	82	64.784	Ciona_intestinalis
ENSG00000198917	SPOUT1	94	55.028	ENSCSAVG00000006037	-	83	61.184	Ciona_savignyi
ENSG00000198917	SPOUT1	99	94.667	ENSCANG00000029127	SPOUT1	99	94.667	Colobus_angolensis_palliatus
ENSG00000198917	SPOUT1	99	89.812	ENSCGRG00001022370	Spout1	100	89.812	Cricetulus_griseus_chok1gshd
ENSG00000198917	SPOUT1	86	83.282	ENSCGRG00000008439	Spout1	90	87.500	Cricetulus_griseus_crigri
ENSG00000198917	SPOUT1	90	69.617	ENSCSEG00000015216	spout1	88	73.510	Cynoglossus_semilaevis
ENSG00000198917	SPOUT1	95	67.131	ENSCVAG00000015713	spout1	84	68.308	Cyprinodon_variegatus
ENSG00000198917	SPOUT1	80	76.080	ENSDARG00000019707	spout1	78	76.094	Danio_rerio
ENSG00000198917	SPOUT1	85	91.850	ENSDNOG00000007388	SPOUT1	100	91.850	Dasypus_novemcinctus
ENSG00000198917	SPOUT1	99	91.733	ENSDORG00000008670	Spout1	99	91.200	Dipodomys_ordii
ENSG00000198917	SPOUT1	93	47.632	FBgn0033473	CG12128	64	52.244	Drosophila_melanogaster
ENSG00000198917	SPOUT1	63	64.609	ENSETEG00000003614	-	61	63.374	Echinops_telfairi
ENSG00000198917	SPOUT1	93	58.592	ENSEBUG00000005700	spout1	90	61.468	Eptatretus_burgeri
ENSG00000198917	SPOUT1	88	94.529	ENSEASG00005007715	SPOUT1	92	90.476	Equus_asinus_asinus
ENSG00000198917	SPOUT1	99	94.652	ENSECAG00000010177	SPOUT1	99	94.652	Equus_caballus
ENSG00000198917	SPOUT1	95	50.769	ENSEEUG00000011006	-	77	57.718	Erinaceus_europaeus
ENSG00000198917	SPOUT1	97	64.946	ENSELUG00000022737	spout1	96	65.574	Esox_lucius
ENSG00000198917	SPOUT1	99	94.400	ENSFCAG00000030593	SPOUT1	94	94.400	Felis_catus
ENSG00000198917	SPOUT1	59	72.549	ENSFALG00000001420	SPOUT1	96	71.728	Ficedula_albicollis
ENSG00000198917	SPOUT1	99	92.513	ENSFDAG00000012125	SPOUT1	98	92.761	Fukomys_damarensis
ENSG00000198917	SPOUT1	95	66.852	ENSFHEG00000000075	spout1	85	68.405	Fundulus_heteroclitus
ENSG00000198917	SPOUT1	94	64.972	ENSGMOG00000015985	spout1	81	70.805	Gadus_morhua
ENSG00000198917	SPOUT1	97	73.699	ENSGALG00000004622	SPOUT1	96	73.699	Gallus_gallus
ENSG00000198917	SPOUT1	96	67.222	ENSGAFG00000013577	spout1	94	66.389	Gambusia_affinis
ENSG00000198917	SPOUT1	80	78.146	ENSGAGG00000021109	SPOUT1	91	78.146	Gopherus_agassizii
ENSG00000198917	SPOUT1	100	99.202	ENSGGOG00000014228	SPOUT1	100	99.202	Gorilla_gorilla
ENSG00000198917	SPOUT1	96	69.146	ENSHBUG00000008743	spout1	96	68.306	Haplochromis_burtoni
ENSG00000198917	SPOUT1	100	90.716	ENSHGLG00000011378	SPOUT1	100	90.716	Heterocephalus_glaber_female
ENSG00000198917	SPOUT1	99	91.129	ENSHGLG00100018401	SPOUT1	98	91.375	Heterocephalus_glaber_male
ENSG00000198917	SPOUT1	93	69.914	ENSHCOG00000001622	spout1	80	76.174	Hippocampus_comes
ENSG00000198917	SPOUT1	97	68.033	ENSIPUG00000006486	spout1	97	67.480	Ictalurus_punctatus
ENSG00000198917	SPOUT1	99	91.935	ENSSTOG00000015657	SPOUT1	98	92.183	Ictidomys_tridecemlineatus
ENSG00000198917	SPOUT1	93	66.379	ENSKMAG00000009988	spout1	79	71.141	Kryptolebias_marmoratus
ENSG00000198917	SPOUT1	95	67.227	ENSLBEG00000024217	spout1	80	73.770	Labrus_bergylta
ENSG00000198917	SPOUT1	80	75.920	ENSLACG00000015521	SPOUT1	97	69.231	Latimeria_chalumnae
ENSG00000198917	SPOUT1	96	69.890	ENSLOCG00000004143	spout1	95	69.890	Lepisosteus_oculatus
ENSG00000198917	SPOUT1	99	93.316	ENSLAFG00000014778	SPOUT1	99	93.316	Loxodonta_africana
ENSG00000198917	SPOUT1	99	97.333	ENSMFAG00000016739	SPOUT1	99	97.333	Macaca_fascicularis
ENSG00000198917	SPOUT1	99	97.333	ENSMMUG00000047511	SPOUT1	99	97.333	Macaca_mulatta
ENSG00000198917	SPOUT1	99	97.067	ENSMNEG00000042898	SPOUT1	99	97.067	Macaca_nemestrina
ENSG00000198917	SPOUT1	99	97.067	ENSMLEG00000028562	SPOUT1	99	97.067	Mandrillus_leucophaeus
ENSG00000198917	SPOUT1	94	69.188	ENSMAMG00000018243	spout1	92	68.627	Mastacembelus_armatus
ENSG00000198917	SPOUT1	90	70.118	ENSMZEG00005003159	spout1	87	69.527	Maylandia_zebra
ENSG00000198917	SPOUT1	99	73.387	ENSMGAG00000004568	SPOUT1	97	73.387	Meleagris_gallopavo
ENSG00000198917	SPOUT1	100	90.716	ENSMAUG00000021158	Spout1	93	90.451	Mesocricetus_auratus
ENSG00000198917	SPOUT1	100	93.883	ENSMICG00000017649	SPOUT1	100	93.883	Microcebus_murinus
ENSG00000198917	SPOUT1	95	66.480	ENSMMOG00000004595	spout1	94	66.574	Mola_mola
ENSG00000198917	SPOUT1	99	78.284	ENSMODG00000006461	-	99	78.016	Monodelphis_domestica
ENSG00000198917	SPOUT1	94	69.492	ENSMALG00000012358	spout1	92	68.927	Monopterus_albus
ENSG00000198917	SPOUT1	99	90.933	MGP_CAROLIEiJ_G0023384	Spout1	97	90.933	Mus_caroli
ENSG00000198917	SPOUT1	99	90.133	ENSMUSG00000039660	Spout1	97	90.133	Mus_musculus
ENSG00000198917	SPOUT1	100	90.716	MGP_PahariEiJ_G0024841	Spout1	98	90.716	Mus_pahari
ENSG00000198917	SPOUT1	99	90.400	MGP_SPRETEiJ_G0024301	Spout1	97	90.400	Mus_spretus
ENSG00000198917	SPOUT1	99	88.976	ENSMPUG00000013017	SPOUT1	97	89.211	Mustela_putorius_furo
ENSG00000198917	SPOUT1	97	88.767	ENSMLUG00000014330	SPOUT1	95	88.767	Myotis_lucifugus
ENSG00000198917	SPOUT1	89	91.940	ENSNGAG00000000907	Spout1	98	92.097	Nannospalax_galili
ENSG00000198917	SPOUT1	61	66.038	ENSNBRG00000007733	spout1	74	71.144	Neolamprologus_brichardi
ENSG00000198917	SPOUT1	100	97.074	ENSNLEG00000017619	SPOUT1	100	97.074	Nomascus_leucogenys
ENSG00000198917	SPOUT1	86	47.967	ENSMEUG00000002090	-	57	67.532	Notamacropus_eugenii
ENSG00000198917	SPOUT1	80	71.753	ENSOPRG00000010742	SPOUT1	76	71.753	Ochotona_princeps
ENSG00000198917	SPOUT1	94	89.266	ENSODEG00000002093	-	93	88.701	Octodon_degus
ENSG00000198917	SPOUT1	96	68.595	ENSONIG00000011299	spout1	96	68.306	Oreochromis_niloticus
ENSG00000198917	SPOUT1	94	73.389	ENSOANG00000003336	SPOUT1	89	73.389	Ornithorhynchus_anatinus
ENSG00000198917	SPOUT1	99	91.444	ENSOCUG00000008882	-	99	91.444	Oryctolagus_cuniculus
ENSG00000198917	SPOUT1	88	74.405	ENSOCUG00000016127	-	87	76.074	Oryctolagus_cuniculus
ENSG00000198917	SPOUT1	96	71.547	ENSOCUG00000026059	-	97	71.547	Oryctolagus_cuniculus
ENSG00000198917	SPOUT1	91	69.388	ENSORLG00000004049	spout1	93	69.939	Oryzias_latipes
ENSG00000198917	SPOUT1	99	66.488	ENSORLG00020009297	spout1	86	69.939	Oryzias_latipes_hni
ENSG00000198917	SPOUT1	99	66.756	ENSORLG00015016211	spout1	86	70.245	Oryzias_latipes_hsok
ENSG00000198917	SPOUT1	99	67.024	ENSOMEG00000011687	spout1	79	74.013	Oryzias_melastigma
ENSG00000198917	SPOUT1	95	94.986	ENSOGAG00000001655	SPOUT1	97	92.453	Otolemur_garnettii
ENSG00000198917	SPOUT1	99	86.133	ENSOARG00000009282	SPOUT1	97	86.133	Ovis_aries
ENSG00000198917	SPOUT1	100	98.936	ENSPPAG00000001094	SPOUT1	100	98.936	Pan_paniscus
ENSG00000198917	SPOUT1	99	90.909	ENSPPRG00000014948	SPOUT1	100	87.968	Panthera_pardus
ENSG00000198917	SPOUT1	99	89.757	ENSPTIG00000010445	SPOUT1	99	85.942	Panthera_tigris_altaica
ENSG00000198917	SPOUT1	100	99.202	ENSPTRG00000023427	SPOUT1	100	99.202	Pan_troglodytes
ENSG00000198917	SPOUT1	81	97.377	ENSPANG00000025932	SPOUT1	96	97.377	Papio_anubis
ENSG00000198917	SPOUT1	94	67.898	ENSPKIG00000025099	spout1	79	73.000	Paramormyrops_kingsleyae
ENSG00000198917	SPOUT1	80	79.801	ENSPSIG00000018152	SPOUT1	93	79.605	Pelodiscus_sinensis
ENSG00000198917	SPOUT1	91	70.262	ENSPMGG00000004788	spout1	88	71.166	Periophthalmus_magnuspinnatus
ENSG00000198917	SPOUT1	100	90.981	ENSPEMG00000009348	Spout1	100	90.981	Peromyscus_maniculatus_bairdii
ENSG00000198917	SPOUT1	99	79.144	ENSPCIG00000030118	SPOUT1	99	79.144	Phascolarctos_cinereus
ENSG00000198917	SPOUT1	95	67.318	ENSPFOG00000016043	SPOUT1	83	71.947	Poecilia_formosa
ENSG00000198917	SPOUT1	95	67.318	ENSPFOG00000022119	spout1	83	71.947	Poecilia_formosa
ENSG00000198917	SPOUT1	97	66.667	ENSPLAG00000021861	spout1	80	71.947	Poecilia_latipinna
ENSG00000198917	SPOUT1	97	66.667	ENSPMEG00000009246	-	80	71.947	Poecilia_mexicana
ENSG00000198917	SPOUT1	97	66.667	ENSPMEG00000010063	spout1	94	72.093	Poecilia_mexicana
ENSG00000198917	SPOUT1	80	68.874	ENSPREG00000022001	spout1	94	68.874	Poecilia_reticulata
ENSG00000198917	SPOUT1	100	98.138	ENSPPYG00000019664	-	79	98.138	Pongo_abelii
ENSG00000198917	SPOUT1	80	63.696	ENSPCAG00000012215	SPOUT1	78	63.907	Procavia_capensis
ENSG00000198917	SPOUT1	100	93.085	ENSPCOG00000002584	SPOUT1	100	93.085	Propithecus_coquereli
ENSG00000198917	SPOUT1	80	73.203	ENSPVAG00000003454	SPOUT1	77	73.203	Pteropus_vampyrus
ENSG00000198917	SPOUT1	96	69.146	ENSPNYG00000003463	spout1	96	68.306	Pundamilia_nyererei
ENSG00000198917	SPOUT1	97	68.120	ENSPNAG00000016265	spout1	96	68.120	Pygocentrus_nattereri
ENSG00000198917	SPOUT1	100	90.716	ENSRNOG00000025711	Spout1	100	90.451	Rattus_norvegicus
ENSG00000198917	SPOUT1	99	96.267	ENSRBIG00000026633	SPOUT1	99	96.267	Rhinopithecus_bieti
ENSG00000198917	SPOUT1	99	96.533	ENSRROG00000038155	SPOUT1	99	96.533	Rhinopithecus_roxellana
ENSG00000198917	SPOUT1	100	96.277	ENSSBOG00000032987	SPOUT1	100	96.277	Saimiri_boliviensis_boliviensis
ENSG00000198917	SPOUT1	95	79.552	ENSSHAG00000018857	SPOUT1	99	79.552	Sarcophilus_harrisii
ENSG00000198917	SPOUT1	91	70.262	ENSSFOG00015002867	spout1	91	70.245	Scleropages_formosus
ENSG00000198917	SPOUT1	94	67.507	ENSSMAG00000009786	spout1	92	66.761	Scophthalmus_maximus
ENSG00000198917	SPOUT1	94	67.978	ENSSDUG00000007894	spout1	92	67.606	Seriola_dumerili
ENSG00000198917	SPOUT1	94	68.451	ENSSLDG00000014944	spout1	92	67.887	Seriola_lalandi_dorsalis
ENSG00000198917	SPOUT1	98	74.865	ENSSPUG00000014052	SPOUT1	97	74.595	Sphenodon_punctatus
ENSG00000198917	SPOUT1	91	66.667	ENSSPAG00000005823	spout1	84	70.513	Stegastes_partitus
ENSG00000198917	SPOUT1	99	93.333	ENSSSCG00000005662	SPOUT1	99	93.600	Sus_scrofa
ENSG00000198917	SPOUT1	93	74.212	ENSTGUG00000004201	SPOUT1	86	79.264	Taeniopygia_guttata
ENSG00000198917	SPOUT1	94	66.856	ENSTRUG00000024910	spout1	91	66.477	Takifugu_rubripes
ENSG00000198917	SPOUT1	94	67.614	ENSTNIG00000007505	spout1	97	67.614	Tetraodon_nigroviridis
ENSG00000198917	SPOUT1	80	72.000	ENSTBEG00000007505	SPOUT1	77	72.000	Tupaia_belangeri
ENSG00000198917	SPOUT1	80	74.916	ENSTTRG00000011616	SPOUT1	77	74.916	Tursiops_truncatus
ENSG00000198917	SPOUT1	99	93.850	ENSUAMG00000016285	SPOUT1	99	93.850	Ursus_americanus
ENSG00000198917	SPOUT1	99	93.850	ENSUMAG00000020628	SPOUT1	99	93.850	Ursus_maritimus
ENSG00000198917	SPOUT1	91	92.690	ENSVVUG00000025999	SPOUT1	97	92.447	Vulpes_vulpes
ENSG00000198917	SPOUT1	94	70.739	ENSXETG00000004745	spout1	94	75.667	Xenopus_tropicalis
ENSG00000198917	SPOUT1	95	67.598	ENSXCOG00000001342	spout1	83	71.947	Xiphophorus_couchianus
ENSG00000198917	SPOUT1	97	67.486	ENSXMAG00000005778	spout1	96	66.667	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000776	kinetochore	25657325.	IDA	Component
GO:0000777	condensed chromosome kinetochore	-	IEA	Component
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	21750715.	IPI	Function
GO:0005737	cytoplasm	-	IEA	Component
GO:0007049	cell cycle	-	IEA	Process
GO:0008168	methyltransferase activity	-	IEA	Function
GO:0010608	posttranscriptional regulation of gene expression	28431233.	IMP	Process
GO:0031616	spindle pole centrosome	25657325.	IDA	Component
GO:0032259	methylation	-	IEA	Process
GO:0035196	production of miRNAs involved in gene silencing by miRNA	28431233.	IMP	Process
GO:0035198	miRNA binding	28431233.	IDA	Function
GO:0051301	cell division	-	IEA	Process
GO:0051661	maintenance of centrosome location	25657325.	IMP	Process
GO:0072686	mitotic spindle	25657325.	IDA	Component