EuRBPDB

Basic Information
Cancer Related Information

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000204186 (Gene tree)
Gene ID: 57683
Gene Symbol: ZDBF2
Alias: FLJ45338|KIAA1571
Full Name: zinc finger DBF-type containing 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 39,798 bases
Position: chr2:206,274,641-206,314,438
Accession: 29313
RBP type: non-canonical RBP
Summary: This gene encodes a protein containing DBF4-type zinc finger domains. This gene is imprinted and paternally expressed in lymphocytes but is more stochastically expressed in the placenta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000374423	ZDBF2-201	10296	XM_011511532	ENSP00000363545	2354 (aa)	XP_011509834	Q9HCK1
ENST00000611847	ZDBF2-202	9890	XM_017004573	ENSP00000478626	2352 (aa)	XP_016860062	N0DVX5
ENST00000649441	ZDBF2-206	2940	-	ENSP00000496863	838 (aa)	-	-
ENST00000648361	ZDBF2-203	8900	-	ENSP00000497292	69 (aa)	-	-
ENST00000650097	ZDBF2-211	2779	-	ENSP00000497304	782 (aa)	-	-
ENST00000649650	ZDBF2-209	10303	XM_005246711	ENSP00000497308	2354 (aa)	XP_005246768	N0DVB2
ENST00000649525	ZDBF2-207	4489	-	ENSP00000497803	1424 (aa)	-	-
ENST00000649285	ZDBF2-204	8920	-	ENSP00000497978	68 (aa)	-	-
ENST00000649998	ZDBF2-210	9706	-	ENSP00000497521	753 (aa)	-	-
ENST00000649289	ZDBF2-205	1770	-	ENSP00000497884	69 (aa)	-	-
ENST00000649636	ZDBF2-208	830	-	ENSP00000498067	206 (aa)	-	-

Gene Model

Click here to download ENSG00000204186's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000204186	Body Mass Index	2E-7	25673413
ENSG00000204186	Body Mass Index	4E-7	25673413
ENSG00000204186	Body Mass Index	3E-8	26604143

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000204186	rs55677225	2	206295628	?	Body mass index	30595370			EFO_0004340

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000204186's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000204186	ZDBF2	96	53.883	ENSMUSG00000027520	Zdbf2	88	77.273	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003676	nucleic acid binding	-	IEA	Function
GO:0008270	zinc ion binding	-	IEA	Function

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr2	206310161	Frame_Shift_Del	novel	*A1879Lfs35**	0.15
ACC	chr2	206305178	Missense_Mutation	novel	S217I	0.3
ACC	chr2	206305544	Missense_Mutation	rs773248063	C339Y	0.3
ACC	chr2	206309298	Silent	novel	T1590T	0.39
ACC	chr2	206309609	Missense_Mutation	novel	R1694I	0.41
BLCA	chr2	206305064	Frame_Shift_Ins	rs781132593	*V182Sfs4**	0.46
BLCA	chr2	206307037	Missense_Mutation	NA	L837V	0.41
BLCA	chr2	206304872	Missense_Mutation	novel	E115A	0.11
BLCA	chr2	206306824	Missense_Mutation	novel	H766Y	0.54
BLCA	chr2	206307779	Missense_Mutation	novel	S1084C	0.31
BLCA	chr2	206310668	Missense_Mutation	rs765117268	R2047Q	0.33
BLCA	chr2	206310755	Missense_Mutation	rs561231274	R2076H	0.47
BLCA	chr2	206307305	Missense_Mutation	NA	S926L	0.33
BLCA	chr2	206306110	Missense_Mutation	novel	D528H	0.14
BLCA	chr2	206297284	Silent	novel	Q33Q	0.94
BLCA	chr2	206305939	Nonsense_Mutation	NA	E471*	0.83
BLCA	chr2	206307457	Nonsense_Mutation	novel	E977*	0.78
BLCA	chr2	206309203	Missense_Mutation	NA	D1559Y	0.9
BLCA	chr2	206311626	3'UTR	novel		0.93
BLCA	chr2	206304992	Missense_Mutation	NA	I155T	0.56
BLCA	chr2	206311112	Missense_Mutation	novel	Y2195C	0.26
BLCA	chr2	206304860	Missense_Mutation	NA	S111L	0.41
BLCA	chr2	206305478	Missense_Mutation	NA	S317F	0.38
BLCA	chr2	206307559	Missense_Mutation	novel	V1011I	0.16
BLCA	chr2	206304901	Missense_Mutation	NA	Q125E	0.25
BLCA	chr2	206297333	Missense_Mutation	novel	D50H	0.28
BLCA	chr2	206307711	Silent	novel	L1061L	0.18
BLCA	chr2	206310861	Silent	rs748503293	P2111P	0.16
BLCA	chr2	206305929	Missense_Mutation	NA	M467I	0.35
BLCA	chr2	206307521	Nonsense_Mutation	NA	S998*	0.07
BLCA	chr2	206309782	Missense_Mutation	novel	C1752G	0.27
BRCA	chr2	206309653	Missense_Mutation	NA	A1709T	0.39
BRCA	chr2	206305646	Missense_Mutation	NA	S373L	0.32
BRCA	chr2	206307873	Missense_Mutation	novel	K1115N	0.2
BRCA	chr2	206304838	Nonsense_Mutation	NA	E104*	0.32
BRCA	chr2	206309884	Missense_Mutation	NA	D1786Y	0.38
BRCA	chr2	206309371	Missense_Mutation	NA	E1615Q	0.44
BRCA	chr2	206309548	Missense_Mutation	NA	H1674D	0.36
BRCA	chr2	206306653	Missense_Mutation	NA	D709Y	0.35
BRCA	chr2	206306696	Missense_Mutation	novel	Q723L	0.82
BRCA	chr2	206304881	Missense_Mutation	novel	H118L	0.05
BRCA	chr2	206310996	Silent	NA	V2156V	0.17
BRCA	chr2	206304870	Silent	novel	I114I	0.21
BRCA	chr2	206306657	Missense_Mutation	NA	S710C	0.43
BRCA	chr2	206308112	Missense_Mutation	NA	C1195S	0.43
BRCA	chr2	206310640	Missense_Mutation	NA	D2038H	0.31
BRCA	chr2	206311620	3'UTR	novel		0.43
BRCA	chr2	206305733	Missense_Mutation	novel	R402I	0.09
BRCA	chr2	206311212	Silent	rs769931510	S2228S	0.86
BRCA	chr2	206307942	Silent	NA	V1138V	0.14
BRCA	chr2	206308672	Missense_Mutation	novel	Q1382E	0.11
BRCA	chr2	206305825	Missense_Mutation	NA	E433K	0.26
BRCA	chr2	206307596	Missense_Mutation	NA	R1023I	0.26
BRCA	chr2	206308970	Missense_Mutation	NA	E1481G	0.21
BRCA	chr2	206309552	Missense_Mutation	rs749703720	R1675Q	0.09
BRCA	chr2	206311574	Missense_Mutation	NA	R2349I	0.12
BRCA	chr2	206307955	Nonsense_Mutation	novel	E1143*	0.2
BRCA	chr2	206311057	Missense_Mutation	NA	H2177D	0.18
BRCA	chr2	206307905	Missense_Mutation	novel	S1126Y	0.08
BRCA	chr2	206310348	Silent	novel	A1940A	0.12
BRCA	chr2	206310164	Frame_Shift_Del	NA	*A1879Vfs35**	0.15
BRCA	chr2	206311589	In_Frame_Ins	novel		0.21
BRCA	chr2	206311591	Nonstop_Mutation	novel	2355Qext8	0.12
BRCA	chr2	206306266	Nonsense_Mutation	NA	E580*	0.17
BRCA	chr2	206311275	Silent	novel	L2249L	0.11
BRCA	chr2	206309432	Missense_Mutation	novel	S1635Y	0.08
BRCA	chr2	206311211	Missense_Mutation	rs781279011	S2228L	0.15
CESC	chr2	206309877	Missense_Mutation	NA	K1783N	0.38
CESC	chr2	206310477	Missense_Mutation	NA	K1983N	0.33
CESC	chr2	206310959	Missense_Mutation	rs764750291	R2144I	0.55
CESC	chr2	206310145	Frame_Shift_Del	rs770232797	*K1875Rfs39**	0.52
CESC	chr2	206310215	Missense_Mutation	novel	S1896T	0.12
CESC	chr2	206311247	Missense_Mutation	novel	S2240C	0.35
CESC	chr2	206306905	Missense_Mutation	NA	D793H	0.33
CESC	chr2	206310497	Missense_Mutation	novel	V1990A	0.25
CESC	chr2	206309230	Missense_Mutation	NA	I1568L	0.38
CESC	chr2	206306232	Silent	NA	T568T	0.37
CESC	chr2	206305116	Silent	rs538759150	N196N	0.25
CESC	chr2	206309047	Missense_Mutation	NA	Q1507E	0.22
CESC	chr2	206309167	Missense_Mutation	NA	Q1547E	0.36
CESC	chr2	206306927	Missense_Mutation	novel	S800L	0.14
CESC	chr2	206307085	Missense_Mutation	novel	Q853E	0.63
CESC	chr2	206305699	Missense_Mutation	NA	E391K	0.32
CESC	chr2	206308802	Missense_Mutation	novel	S1425C	0.31
COAD	chr2	206309962	Missense_Mutation	NA	P1812T	0.14
COAD	chr2	206309947	Missense_Mutation	NA	V1807I	0.14
COAD	chr2	206310290	Missense_Mutation	novel	P1921L	0.13
COAD	chr2	206308895	Missense_Mutation	NA	C1456F	0.16
COAD	chr2	206306297	Missense_Mutation	NA	E590G	0.26
COAD	chr2	206306725	Nonsense_Mutation	NA	E733*	0.42
COAD	chr2	206306990	Missense_Mutation	NA	S821I	0.34
COAD	chr2	206309466	Missense_Mutation	NA	K1646N	0.36
COAD	chr2	206309756	Missense_Mutation	rs201499131	P1743L	0.49
COAD	chr2	206311212	Silent	rs769931510	S2228S	0.16
COAD	chr2	206305862	Missense_Mutation	NA	S445C	0.23
COAD	chr2	206297338	Silent	novel	V51V	0.29
COAD	chr2	206305348	Missense_Mutation	novel	D274Y	0.21
COAD	chr2	206309436	Missense_Mutation	novel	M1636I	0.25
COAD	chr2	206304727	Missense_Mutation	NA	D67Y	0.41
COAD	chr2	206306107	Missense_Mutation	NA	V527F	0.36
COAD	chr2	206306332	Nonsense_Mutation	NA	G602*	0.28
COAD	chr2	206307390	Silent	NA	F954F	0.32
COAD	chr2	206309647	Missense_Mutation	novel	A1707T	0.08
COAD	chr2	206309648	Missense_Mutation	novel	A1707V	0.08
COAD	chr2	206305461	In_Frame_Del	NA	K312_T313del	0.31
COAD	chr2	206311173	Silent	NA	I2215I	0.16
COAD	chr2	206307483	Silent	rs370841894	H985H	0.38
COAD	chr2	206304838	Missense_Mutation	rs779996852	E104K	0.23
COAD	chr2	206306364	Frame_Shift_Del	NA	*K613Nfs34**	0.38
COAD	chr2	206309977	Missense_Mutation	NA	L1817I	0.12
COAD	chr2	206305117	Missense_Mutation	NA	D197N	0.3
COAD	chr2	206310842	Missense_Mutation	rs780769661	A2105V	0.34
COAD	chr2	206308769	Missense_Mutation	NA	S1414F	0.41
COAD	chr2	206305007	Frame_Shift_Del	NA	*R160Kfs5**	0.42
COAD	chr2	206309704	Frame_Shift_Del	rs745875253	*K1728Nfs5**	0.48
COAD	chr2	206308048	Nonsense_Mutation	NA	R1174*	0.36
COAD	chr2	206309597	Missense_Mutation	rs757506025	R1690Q	0.32
COAD	chr2	206305968	Silent	novel	I480I	0.22
COAD	chr2	206281852	Translation_Start_Site	novel	M1?	0.14
COAD	chr2	206306517	Silent	NA	S663S	0.41
COAD	chr2	206306850	Silent	rs778537783	R774R	0.37
COAD	chr2	206311638	3'UTR	novel		0.09
COAD	chr2	206308087	Missense_Mutation	NA	L1187V	0.3
COAD	chr2	206308268	Missense_Mutation	NA	S1247Y	0.51
COAD	chr2	206305512	Missense_Mutation	novel	K328N	0.2
COAD	chr2	206309452	Nonsense_Mutation	NA	G1642*	0.19
COAD	chr2	206309837	Missense_Mutation	NA	R1770K	0.1
COAD	chr2	206307579	Silent	NA	A1017A	0.06
COAD	chr2	206307425	Missense_Mutation	novel	A966E	0.05
COAD	chr2	206309033	Missense_Mutation	NA	S1502F	0.34
COAD	chr2	206311212	Silent	rs769931510	S2228S	0.69
COAD	chr2	206311334	Frame_Shift_Del	novel	L2270*	0.42
COAD	chr2	206308216	Missense_Mutation	NA	D1230N	0.35
COAD	chr2	206307600	Silent	NA	K1024K	0.18
COAD	chr2	206308873	Missense_Mutation	NA	V1449I	0.21
COAD	chr2	206309495	Missense_Mutation	NA	K1656T	0.25
COAD	chr2	206305420	Frame_Shift_Ins	novel	*L298Yfs10**	0.13
COAD	chr2	206307739	Nonsense_Mutation	novel	K1071delinsTRI*	0.04
COAD	chr2	206311673	3'UTR	novel		0.08
COAD	chr2	206311674	3'UTR	novel		0.08
COAD	chr2	206307254	Missense_Mutation	NA	N909I	0.53
COAD	chr2	206307522	Frame_Shift_Del	NA	*T1000Qfs3**	0.18
COAD	chr2	206310946	Missense_Mutation	NA	L2140F	0.37
COAD	chr2	206310931	Silent	NA	L2135L	0.28
COAD	chr2	206309713	Missense_Mutation	rs531064136	R1729C	0.77
DLBC	chr2	206310145	Missense_Mutation	rs746951501	K1873E	0.3
ESCA	chr2	206309704	Frame_Shift_Del	rs745875253	*K1728Nfs5**	0.63
ESCA	chr2	206307294	Silent	novel	I922I	0.23
ESCA	chr2	206310199	Missense_Mutation	novel	Q1891E	0.14
ESCA	chr2	206308727	Missense_Mutation	novel	D1400G	0.54
ESCA	chr2	206309586	In_Frame_Ins	novel	E1686_A1687insQFSNTIYSKRQKITSV	0.18
ESCA	chr2	206305064	Frame_Shift_Ins	rs781132593	*V182Sfs4**	0.52
ESCA	chr2	206306661	Silent	novel	P711P	0.1
ESCA	chr2	206311175	Missense_Mutation	rs199913989	R2216Q	0.32
GBM	chr2	206309199	Silent	novel	V1557V	0.67
GBM	chr2	206311428	Silent	novel	R2300R	0.36
GBM	chr2	206311538	Missense_Mutation	rs767560772	R2337H	0.35
GBM	chr2	206306285	Missense_Mutation	NA	D586G	0.3
GBM	chr2	206305851	Silent	novel	K441K	0.26
GBM	chr2	206307841	Missense_Mutation	novel	K1105Q	0.07
GBM	chr2	206308548	Silent	novel	V1340V	0.27
GBM	chr2	206310693	Silent	novel	P2055P	0.12
GBM	chr2	206311472	Missense_Mutation	rs370582691	R2315Q	0.37
GBM	chr2	206309362	Missense_Mutation	novel	I1612L	0.27
GBM	chr2	206304985	Missense_Mutation	NA	H153Y	0.39
GBM	chr2	206308414	Missense_Mutation	rs190838042	V1296I	0.08
GBM	chr2	206309718	Silent	rs140337696	S1730S	0.35
GBM	chr2	206308298	Missense_Mutation	NA	P1257H	0.36
GBM	chr2	206306678	Missense_Mutation	rs748753432	S717L	0.11
GBM	chr2	206309552	Missense_Mutation	rs749703720	R1675Q	0.27
GBM	chr2	206309718	Silent	rs140337696	S1730S	0.17
GBM	chr2	206311093	Missense_Mutation	novel	G2189C	0.3
GBM	chr2	206308048	Nonsense_Mutation	NA	R1174*	0.39
GBM	chr2	206310323	Missense_Mutation	rs763186071	R1932H	0.27
GBM	chr2	206310092	Missense_Mutation	NA	F1855C	0.51
HNSC	chr2	206305320	Missense_Mutation	novel	M264I	0.55
HNSC	chr2	206307539	Missense_Mutation	novel	S1004C	0.16
HNSC	chr2	206306807	Missense_Mutation	novel	S760L	0.21
HNSC	chr2	206307157	Missense_Mutation	novel	H877Y	0.25
HNSC	chr2	206307789	In_Frame_Ins	novel	L1087_Q1088insVRTKSSCSAG	0.25
HNSC	chr2	206309560	Missense_Mutation	novel	H1678Y	0.74
HNSC	chr2	206310152	Missense_Mutation	rs201770559	K1875R	0.14
HNSC	chr2	206304897	In_Frame_Ins	novel	K123_S124insHILM	0.15
HNSC	chr2	206309233	Missense_Mutation	novel	D1569H	0.25
HNSC	chr2	206311386	Missense_Mutation	NA	M2286I	0.67
HNSC	chr2	206304746	Missense_Mutation	novel	T73N	0.36
HNSC	chr2	206308302	Missense_Mutation	novel	E1258D	0.26
HNSC	chr2	206311476	Missense_Mutation	novel	Q2316H	0.43
KICH	chr2	206306578	Missense_Mutation	NA	E684K	0.9
KIRC	chr2	206305336	Missense_Mutation	NA	V270F	0.17
KIRC	chr2	206309713	Missense_Mutation	rs531064136	R1729C	0.07
KIRC	chr2	206309742	Missense_Mutation	NA	E1738D	0.25
KIRC	chr2	206309556	Silent	NA	T1676T	0.2
KIRP	chr2	206305839	Missense_Mutation	novel	D437E	0.08
KIRP	chr2	206306850	Silent	rs778537783	R774R	0.15
LAML	chr2	206308958	Missense_Mutation	novel	D1477A	0.06
LAML	chr2	206309325	Silent	novel	E1599E	0.09
LAML	chr2	206310806	Missense_Mutation	novel	G2093E	0.2
LAML	chr2	206309491	Missense_Mutation	novel	D1655Y	0.06
LGG	chr2	206304912	Silent	rs143619911	T128T	0.16
LGG	chr2	206306971	Missense_Mutation	novel	V815I	0.08
LGG	chr2	206305037	Missense_Mutation	NA	A170V	0.2
LGG	chr2	206304891	Silent	novel	P121P	0.15
LGG	chr2	206305749	Silent	novel	S407S	0.47
LGG	chr2	206309153	Missense_Mutation	novel	D1542G	0.32
LGG	chr2	206308957	Missense_Mutation	novel	D1477N	0.36
LGG	chr2	206310842	Missense_Mutation	rs780769661	A2105V	0.37
LGG	chr2	206311212	Silent	rs769931510	S2228S	0.39
LGG	chr2	206310426	Frame_Shift_Ins	novel	*P1967Dfs6**	0.09
LGG	chr2	206310427	Missense_Mutation	novel	P1967A	0.09
LGG	chr2	206310044	Frame_Shift_Ins	novel	*D1840Tfs3**	0.15
LGG	chr2	206310046	Missense_Mutation	novel	D1840Y	0.14
LIHC	chr2	206306796	Silent	rs763427850	P756P	0.37
LIHC	chr2	206305247	Missense_Mutation	novel	P240R	0.26
LIHC	chr2	206310023	Nonsense_Mutation	NA	W1832*	0.26
LIHC	chr2	206306185	Frame_Shift_Del	novel	*P554Qfs39**	0.16
LIHC	chr2	206311508	Missense_Mutation	NA	D2327V	0.26
LIHC	chr2	206307977	Missense_Mutation	novel	V1150A	0.4
LIHC	chr2	206306400	Silent	novel	A624A	0.4
LIHC	chr2	206310320	Missense_Mutation	NA	G1931V	0.13
LIHC	chr2	206310084	Silent	novel	E1852E	0.4
LIHC	chr2	206310899	Missense_Mutation	novel	D2124G	0.31
LIHC	chr2	206307403	Missense_Mutation	novel	D959N	0.41
LUAD	chr2	206306815	Missense_Mutation	NA	E763Q	0.28
LUAD	chr2	206311376	Missense_Mutation	novel	S2283L	0.19
LUAD	chr2	206305303	Missense_Mutation	rs748548110	R259G	0.08
LUAD	chr2	206310064	Silent	rs763067950	L1846L	0.36
LUAD	chr2	206304889	Missense_Mutation	NA	P121T	0.42
LUAD	chr2	206281884	Missense_Mutation	NA	R12L	0.25
LUAD	chr2	206306629	Missense_Mutation	NA	S701A	0.07
LUAD	chr2	206307818	Missense_Mutation	NA	W1097L	0.19
LUAD	chr2	206305495	Missense_Mutation	NA	E323K	0.2
LUAD	chr2	206306286	Silent	novel	D586D	0.22
LUAD	chr2	206306716	Missense_Mutation	novel	N730H	0.32
LUAD	chr2	206306826	Missense_Mutation	NA	H766Q	0.34
LUAD	chr2	206310323	Missense_Mutation	NA	R1932L	0.33
LUAD	chr2	206304935	Missense_Mutation	NA	S136L	0.28
LUAD	chr2	206310802	In_Frame_Del	novel	A2092_G2093del	0.4
LUAD	chr2	206311556	Missense_Mutation	NA	R2343Q	0.21
LUAD	chr2	206308946	Missense_Mutation	NA	Y1473F	0.13
LUAD	chr2	206311231	Missense_Mutation	novel	R2235S	0.14
LUAD	chr2	206305664	Missense_Mutation	novel	Q379L	0.17
LUAD	chr2	206307754	Missense_Mutation	novel	G1076C	0.34
LUAD	chr2	206310258	Silent	novel	S1910S	0.23
LUAD	chr2	206310723	Silent	NA	P2065P	0.15
LUAD	chr2	206309316	Missense_Mutation	NA	Q1596H	0.24
LUAD	chr2	206305067	Missense_Mutation	novel	P180H	0.13
LUAD	chr2	206309344	Missense_Mutation	rs201565836	R1606W	0.26
LUAD	chr2	206311311	Missense_Mutation	novel	K2261N	0.22
LUAD	chr2	206305838	Frame_Shift_Del	novel	*D437Vfs14**	0.05
LUAD	chr2	206307325	Missense_Mutation	novel	D933H	0.17
LUAD	chr2	206307037	Missense_Mutation	NA	L837V	0.21
LUAD	chr2	206311574	Missense_Mutation	novel	R2349K	0.1
LUAD	chr2	206307521	Nonsense_Mutation	NA	S998*	0.09
LUAD	chr2	206305585	Missense_Mutation	NA	F353L	0.23
LUAD	chr2	206306972	Missense_Mutation	novel	V815A	0.07
LUAD	chr2	206306023	Missense_Mutation	novel	D499N	0.25
LUAD	chr2	206304740	Missense_Mutation	NA	V71A	0.09
LUAD	chr2	206306393	Missense_Mutation	rs756082291	A622V	0.14
LUAD	chr2	206309568	Silent	NA	L1680L	0.19
LUAD	chr2	206305271	Missense_Mutation	novel	S248L	0.19
LUAD	chr2	206309568	Silent	NA	L1680L	0.3
LUAD	chr2	206305175	Missense_Mutation	novel	V216D	0.18
LUAD	chr2	206308489	Missense_Mutation	novel	G1321C	0.21
LUAD	chr2	206307230	Missense_Mutation	novel	Q901P	0.13
LUAD	chr2	206309723	Missense_Mutation	novel	L1732R	0.08
LUAD	chr2	206304983	Missense_Mutation	novel	V152A	0.15
LUAD	chr2	206306254	Missense_Mutation	NA	S576T	0.19
LUAD	chr2	206310250	In_Frame_Del	novel	D1908_V1911del	0.18
LUAD	chr2	206304972	Silent	novel	P148P	0.38
LUAD	chr2	206306660	Missense_Mutation	rs188595104	P711L	0.23
LUAD	chr2	206310342	Silent	novel	Q1938Q	0.08
LUAD	chr2	206310131	Missense_Mutation	NA	V1868A	0.1
LUAD	chr2	206306464	Missense_Mutation	rs374997578	I646V	0.13
LUSC	chr2	206310464	Missense_Mutation	novel	R1979K	0.36
LUSC	chr2	206308103	Missense_Mutation	NA	N1192S	0.37
LUSC	chr2	206307528	Silent	NA	T1000T	0.2
LUSC	chr2	206310420	Frame_Shift_Del	novel	*E1965Kfs36**	0.08
LUSC	chr2	206309704	Missense_Mutation	novel	K1726E	0.17
LUSC	chr2	206308701	Missense_Mutation	novel	W1391C	0.17
LUSC	chr2	206307818	Missense_Mutation	NA	W1097L	0.26
LUSC	chr2	206310334	Missense_Mutation	rs766753250	Q1936E	0.11
LUSC	chr2	206306162	Missense_Mutation	novel	P545Q	0.35
LUSC	chr2	206307801	Frame_Shift_Ins	rs765952396	*I1094Nfs14**	0.45
LUSC	chr2	206311160	Missense_Mutation	novel	Q2211P	0.61
LUSC	chr2	206310114	Missense_Mutation	novel	D1862E	0.18
LUSC	chr2	206310307	Missense_Mutation	NA	P1927T	0.24
LUSC	chr2	206310308	Missense_Mutation	NA	P1927H	0.24
LUSC	chr2	206311282	Nonsense_Mutation	NA	K2252*	0.41
LUSC	chr2	206308104	Silent	novel	N1192N	0.13
LUSC	chr2	206311371	Missense_Mutation	novel	E2281D	0.19
LUSC	chr2	206309950	Missense_Mutation	novel	I1808L	0.2
LUSC	chr2	206308146	Silent	novel	P1206P	0.22
LUSC	chr2	206305711	Nonsense_Mutation	NA	Q395*	0.2
LUSC	chr2	206308504	Missense_Mutation	NA	D1326N	0.54
LUSC	chr2	206308195	Missense_Mutation	novel	L1223I	0.22
LUSC	chr2	206309998	Missense_Mutation	NA	P1824S	0.09
LUSC	chr2	206308468	Missense_Mutation	novel	H1314N	0.51
LUSC	chr2	206297345	Missense_Mutation	novel	H54D	0.32
LUSC	chr2	206310431	Missense_Mutation	novel	P1968Q	0.37
LUSC	chr2	206311229	Missense_Mutation	novel	L2234S	0.53
LUSC	chr2	206311235	Missense_Mutation	novel	H2236R	0.4
LUSC	chr2	206281903	Silent	NA	L18L	0.35
LUSC	chr2	206308601	Missense_Mutation	novel	S1358N	0.18
LUSC	chr2	206309684	Missense_Mutation	rs776122535	A1719V	0.29
LUSC	chr2	206306130	Missense_Mutation	novel	S534R	0.62
LUSC	chr2	206304897	In_Frame_Ins	novel	K123_S124insHILM	0.08
LUSC	chr2	206306000	Missense_Mutation	NA	S491T	0.19
LUSC	chr2	206304747	Silent	NA	T73T	0.55
LUSC	chr2	206305635	Missense_Mutation	novel	I369M	0.45
LUSC	chr2	206309116	Missense_Mutation	NA	L1530M	0.11
LUSC	chr2	206311353	Silent	NA	P2275P	0.24
LUSC	chr2	206309972	Missense_Mutation	novel	P1815L	0.49
LUSC	chr2	206309785	Missense_Mutation	novel	A1753S	0.14
LUSC	chr2	206309492	Missense_Mutation	rs376406681	D1655G	0.17
LUSC	chr2	206308246	Missense_Mutation	NA	G1240S	0.09
LUSC	chr2	206305734	Missense_Mutation	novel	R402S	0.26
LUSC	chr2	206310940	Missense_Mutation	rs148350329	R2138C	0.16
LUSC	chr2	206311542	Missense_Mutation	NA	E2338D	0.28
LUSC	chr2	206307813	Silent	novel	D1095D	0.38
LUSC	chr2	206306052	Nonsense_Mutation	novel	Y508*	0.67
LUSC	chr2	206310011	Frame_Shift_Ins	novel	*K1830Efs11**	0.66
LUSC	chr2	206306873	Missense_Mutation	NA	S782I	0.35
LUSC	chr2	206304724	Nonsense_Mutation	novel	Q66*	0.3
LUSC	chr2	206307857	Missense_Mutation	novel	E1110V	0.3
LUSC	chr2	206309704	Frame_Shift_Del	rs745875253	*K1728Nfs5**	0.41
LUSC	chr2	206306065	Missense_Mutation	novel	V513I	0.18
LUSC	chr2	206306844	Missense_Mutation	NA	K772N	0.58
LUSC	chr2	206311576	Missense_Mutation	NA	G2350C	0.44
LUSC	chr2	206306651	Missense_Mutation	NA	S708C	0.14
OV	chr2	206307190	Missense_Mutation	NA	E888K	0.16
OV	chr2	206311581	Missense_Mutation	novel	N2351K	0.08
OV	chr2	206308616	Missense_Mutation	NA	S1363I	0.69
OV	chr2	206310804	Silent	novel	A2092A	0.04
OV	chr2	206308257	Missense_Mutation	novel	I1243M	0.04
OV	chr2	206307782	Missense_Mutation	NA	E1085G	0.46
OV	chr2	206310046	Missense_Mutation	novel	D1840N	0.07
OV	chr2	206305063	Missense_Mutation	rs770448989	R179C	0.49
OV	chr2	206305224	Silent	NA	D232D	0.21
OV	chr2	206310646	Missense_Mutation	rs201802013	R2040W	0.47
OV	chr2	206311479	Frame_Shift_Ins	novel	*G2318Rfs12**	0.09
OV	chr2	206308964	Missense_Mutation	novel	Q1479P	0.14
PAAD	chr2	206307480	Silent	novel	K984K	0.24
PAAD	chr2	206306560	Missense_Mutation	novel	D678Y	0.16
PAAD	chr2	206304929	Missense_Mutation	novel	R134Q	0.29
PAAD	chr2	206306056	Nonsense_Mutation	novel	Q510*	0.14
PAAD	chr2	206307925	Missense_Mutation	novel	V1133L	0.16
PAAD	chr2	206308049	Missense_Mutation	rs529263608	R1174Q	0.17
PAAD	chr2	206310647	Missense_Mutation	rs572938202	R2040Q	0.14
PAAD	chr2	206310043	Missense_Mutation	novel	D1839N	0.33
PRAD	chr2	206305290	Missense_Mutation	novel	H254Q	0.27
PRAD	chr2	206311212	Silent	rs769931510	S2228S	0.3
PRAD	chr2	206305123	Missense_Mutation	novel	P199S	0.44
PRAD	chr2	206306215	Missense_Mutation	rs771789452	R563W	0.35
PRAD	chr2	206305400	Missense_Mutation	novel	R291H	0.1
PRAD	chr2	206308383	Missense_Mutation	novel	I1285M	0.08
PRAD	chr2	206311218	Silent	novel	Y2230Y	0.58
READ	chr2	206307483	Silent	rs370841894	H985H	0.44
READ	chr2	206309564	Missense_Mutation	rs754685399	R1679Q	0.11
READ	chr2	206311212	Silent	rs769931510	S2228S	0.21
READ	chr2	206297341	Silent	NA	L52L	0.2
READ	chr2	206307551	Missense_Mutation	NA	H1008L	0.27
READ	chr2	206308672	Nonsense_Mutation	NA	Q1382*	0.55
READ	chr2	206304912	Silent	rs143619911	T128T	0.23
READ	chr2	206310566	Missense_Mutation	NA	S2013Y	0.18
READ	chr2	206307600	Missense_Mutation	novel	K1024N	0.05
READ	chr2	206308126	Missense_Mutation	NA	S1200R	0.1
READ	chr2	206309718	Silent	rs140337696	S1730S	0.21
READ	chr2	206297280	Missense_Mutation	NA	R32I	0.41
READ	chr2	206305294	Nonsense_Mutation	NA	E256*	0.39
READ	chr2	206305939	Nonsense_Mutation	NA	E471*	0.38
READ	chr2	206306463	Missense_Mutation	NA	K645N	0.38
READ	chr2	206307715	Nonsense_Mutation	NA	E1063*	0.32
READ	chr2	206308464	Missense_Mutation	NA	E1312D	0.34
READ	chr2	206308687	Missense_Mutation	NA	E1387K	0.35
READ	chr2	206308802	Missense_Mutation	NA	S1425Y	0.4
READ	chr2	206309850	Missense_Mutation	NA	K1774N	0.45
READ	chr2	206311232	Missense_Mutation	rs751972875	R2235H	0.44
READ	chr2	206305701	Silent	NA	E391E	0.31
READ	chr2	206304896	Missense_Mutation	NA	K123T	0.39
READ	chr2	206307022	Missense_Mutation	novel	D832Y	0.09
READ	chr2	206308990	Missense_Mutation	NA	E1488K	0.21
READ	chr2	206310369	Missense_Mutation	NA	Q1947H	0.25
READ	chr2	206311366	Missense_Mutation	rs764194697	E2280K	0.3
READ	chr2	206311555	Missense_Mutation	NA	R2343W	0.21
SARC	chr2	206311212	Silent	rs769931510	S2228S	0.12
SARC	chr2	206305601	Missense_Mutation	novel	C358F	0.08
SARC	chr2	206308649	Missense_Mutation	rs762568697	F1374S	0.96
SARC	chr2	206308745	Missense_Mutation	novel	G1406V	0.26
SARC	chr2	206309041	Missense_Mutation	NA	P1505S	0.39
SKCM	chr2	206297261	Nonsense_Mutation	NA	Q26*	0.27
SKCM	chr2	206305591	Missense_Mutation	NA	E355K	0.24
SKCM	chr2	206309689	Missense_Mutation	NA	H1721Y	0.26
SKCM	chr2	206311175	Missense_Mutation	rs199913989	R2216Q	0.38
SKCM	chr2	206307715	Missense_Mutation	NA	E1063K	0.53
SKCM	chr2	206307715	Missense_Mutation	NA	E1063K	0.59
SKCM	chr2	206305860	Missense_Mutation	NA	K444N	0.26
SKCM	chr2	206307700	Missense_Mutation	NA	L1058V	0.64
SKCM	chr2	206311427	Missense_Mutation	rs760923997	R2300H	0.48
SKCM	chr2	206310742	Missense_Mutation	NA	E2072K	0.41
SKCM	chr2	206307735	Silent	novel	K1069K	0.45
SKCM	chr2	206311002	Silent	novel	I2158I	0.25
SKCM	chr2	206311155	Silent	novel	E2209E	0.31
SKCM	chr2	206306836	Missense_Mutation	novel	E770K	0.27
SKCM	chr2	206310977	Missense_Mutation	novel	F2150C	0.25
SKCM	chr2	206306010	Silent	rs139933444	T494T	0.33
SKCM	chr2	206306578	Missense_Mutation	NA	E684K	0.19
SKCM	chr2	206309522	Missense_Mutation	NA	G1665E	0.3
SKCM	chr2	206304928	Nonsense_Mutation	rs772203809	R134*	0.33
SKCM	chr2	206310354	Silent	novel	I1942I	0.28
SKCM	chr2	206307541	Missense_Mutation	NA	G1005C	0.16
SKCM	chr2	206297286	Missense_Mutation	novel	S34N	0.18
SKCM	chr2	206310203	Missense_Mutation	NA	A1892V	0.25
SKCM	chr2	206305277	Missense_Mutation	rs745571949	S250L	0.22
SKCM	chr2	206311430	Missense_Mutation	NA	V2301A	0.33
SKCM	chr2	206306215	Missense_Mutation	rs771789452	R563W	0.35
SKCM	chr2	206308535	Missense_Mutation	NA	P1336L	0.28
SKCM	chr2	206306071	Missense_Mutation	NA	E515K	0.54
SKCM	chr2	206281860	Missense_Mutation	NA	R4K	0.25
SKCM	chr2	206305277	Missense_Mutation	rs745571949	S250L	0.34
SKCM	chr2	206305455	Silent	novel	N309N	0.26
SKCM	chr2	206306578	Missense_Mutation	NA	E684K	0.47
SKCM	chr2	206308969	Missense_Mutation	novel	E1481K	0.3
SKCM	chr2	206309346	Silent	novel	R1606R	0.36
SKCM	chr2	206304799	Missense_Mutation	rs755353638	E91K	0.18
SKCM	chr2	206305186	Missense_Mutation	NA	D220N	0.15
SKCM	chr2	206305825	Missense_Mutation	NA	E433K	0.3
SKCM	chr2	206308687	Missense_Mutation	NA	E1387K	0.36
SKCM	chr2	206310954	Silent	NA	K2142K	0.23
SKCM	chr2	206311481	Missense_Mutation	rs574875391	G2318D	0.49
SKCM	chr2	206311585	Missense_Mutation	novel	V2353I	0.08
SKCM	chr2	206305277	Missense_Mutation	rs745571949	S250L	0.25
SKCM	chr2	206305018	Silent	novel	L164L	0.25
SKCM	chr2	206306759	Missense_Mutation	NA	D744A	0.06
SKCM	chr2	206309971	Missense_Mutation	NA	P1815S	0.41
SKCM	chr2	206306484	Silent	novel	K652K	0.31
SKCM	chr2	206307190	Missense_Mutation	NA	E888K	0.17
SKCM	chr2	206307715	Missense_Mutation	NA	E1063K	0.28
SKCM	chr2	206307990	Missense_Mutation	novel	Q1154H	0.37
SKCM	chr2	206310772	Missense_Mutation	NA	H2082Y	0.2
SKCM	chr2	206297370	Missense_Mutation	rs200516787	S62N	0.26
SKCM	chr2	206309472	Silent	novel	V1648V	0.33
SKCM	chr2	206306215	Missense_Mutation	rs771789452	R563W	0.36
SKCM	chr2	206306336	Missense_Mutation	NA	R603K	0.19
SKCM	chr2	206306635	Missense_Mutation	rs184921981	R703C	0.41
SKCM	chr2	206307128	Missense_Mutation	novel	P867L	0.67
SKCM	chr2	206306293	Missense_Mutation	novel	L589F	0.46
SKCM	chr2	206311148	Missense_Mutation	novel	A2207V	0.26
SKCM	chr2	206305393	Missense_Mutation	NA	H289Y	0.73
SKCM	chr2	206306010	Silent	rs139933444	T494T	0.78
SKCM	chr2	206307207	Silent	NA	K893K	0.65
SKCM	chr2	206305929	Missense_Mutation	NA	M467I	0.43
SKCM	chr2	206309956	Missense_Mutation	NA	D1810N	0.37
SKCM	chr2	206310782	Missense_Mutation	NA	R2085M	0.56
SKCM	chr2	206305392	Silent	NA	F288F	0.25
SKCM	chr2	206306384	Missense_Mutation	NA	P619L	0.33
SKCM	chr2	206305399	Missense_Mutation	rs758826273	R291C	0.35
SKCM	chr2	206308014	Silent	NA	L1162L	0.17
SKCM	chr2	206306289	Silent	NA	V587V	0.43
SKCM	chr2	206309925	Silent	NA	R1799R	0.27
SKCM	chr2	206307715	Missense_Mutation	NA	E1063K	0.48
SKCM	chr2	206305456	Missense_Mutation	novel	P310S	0.15
SKCM	chr2	206305457	Missense_Mutation	rs541984086	P310L	0.14
SKCM	chr2	206308461	Silent	NA	R1311R	0.3
SKCM	chr2	206306307	Silent	NA	V593V	0.31
SKCM	chr2	206305475	Missense_Mutation	rs755141434	P316L	0.32
SKCM	chr2	206311211	Missense_Mutation	rs781279011	S2228L	0.46
SKCM	chr2	206306894	Missense_Mutation	novel	E789A	0.44
SKCM	chr2	206309596	Missense_Mutation	rs763893380	R1690W	0.22
SKCM	chr2	206309011	Missense_Mutation	novel	D1495N	0.25
SKCM	chr2	206310143	Missense_Mutation	NA	G1872E	0.21
SKCM	chr2	206305512	Silent	NA	K328K	0.48
SKCM	chr2	206307798	Silent	rs541104769	A1090A	0.29
SKCM	chr2	206310528	Silent	NA	L2000L	0.33
SKCM	chr2	206306215	Missense_Mutation	rs771789452	R563W	0.34
SKCM	chr2	206306651	Missense_Mutation	NA	S708F	0.33
SKCM	chr2	206306839	Missense_Mutation	NA	G771R	0.18
SKCM	chr2	206307578	Missense_Mutation	NA	A1017V	0.11
SKCM	chr2	206310954	Silent	NA	K2142K	0.14
SKCM	chr2	206309659	Missense_Mutation	rs770725241	D1711N	0.43
SKCM	chr2	206307493	Nonsense_Mutation	novel	Q989*	0.21
SKCM	chr2	206311289	Missense_Mutation	novel	S2254F	0.43
SKCM	chr2	206309918	Missense_Mutation	rs746979785	S1797F	0.13
SKCM	chr2	206304916	Missense_Mutation	NA	E130K	0.22
SKCM	chr2	206307415	Missense_Mutation	NA	P963S	0.1
SKCM	chr2	206310413	Missense_Mutation	NA	R1962K	0.38
SKCM	chr2	206305458	Silent	rs377262471	P310P	0.18
SKCM	chr2	206305017	Silent	novel	N163N	0.31
SKCM	chr2	206307256	Missense_Mutation	NA	E910K	0.31
SKCM	chr2	206310562	Missense_Mutation	NA	L2012F	0.29
SKCM	chr2	206311211	Missense_Mutation	rs781279011	S2228L	0.38
SKCM	chr2	206308533	Silent	NA	I1335I	0.31
SKCM	chr2	206310733	Missense_Mutation	rs370168620	I2069V	0.13
SKCM	chr2	206306849	Missense_Mutation	rs200895636	R774Q	0.4
SKCM	chr2	206305978	Missense_Mutation	novel	D484N	0.25
SKCM	chr2	206310228	Silent	NA	V1900V	0.47
SKCM	chr2	206281860	Missense_Mutation	NA	R4K	0.33
SKCM	chr2	206309551	Nonsense_Mutation	rs374690917	R1675*	0.53
SKCM	chr2	206304843	Silent	novel	E105E	0.27
SKCM	chr2	206309571	Silent	NA	Q1681Q	0.18
SKCM	chr2	206305633	Missense_Mutation	novel	I369V	0.4
SKCM	chr2	206308590	Silent	novel	L1354L	0.3
SKCM	chr2	206308591	Nonsense_Mutation	novel	E1355*	0.28
SKCM	chr2	206308483	Missense_Mutation	novel	D1319N	0.44
SKCM	chr2	206305005	Silent	rs750026008	V159V	0.24
SKCM	chr2	206310030	Silent	novel	Q1834Q	0.38
SKCM	chr2	206311443	Silent	novel	R2305R	0.46
SKCM	chr2	206311211	Missense_Mutation	rs781279011	S2228L	0.5
SKCM	chr2	206310348	Silent	rs201220827	A1940A	0.52
SKCM	chr2	206309041	Missense_Mutation	NA	P1505S	0.25
SKCM	chr2	206306494	Missense_Mutation	NA	L656F	0.47
SKCM	chr2	206305168	Missense_Mutation	NA	D214N	0.26
SKCM	chr2	206305584	Silent	NA	A352A	0.17
SKCM	chr2	206308867	Missense_Mutation	NA	C1447G	0.11
SKCM	chr2	206310905	Missense_Mutation	NA	S2126F	0.21
SKCM	chr2	206310328	Missense_Mutation	novel	A1934T	0.51
SKCM	chr2	206305696	Missense_Mutation	NA	E390K	0.23
SKCM	chr2	206306766	Silent	novel	S746S	0.28
SKCM	chr2	206305210	Missense_Mutation	NA	L228F	0.38
SKCM	chr2	206307715	Missense_Mutation	NA	E1063K	0.17
SKCM	chr2	206305491	Silent	NA	I321I	0.22
SKCM	chr2	206308412	Missense_Mutation	novel	S1295F	0.12
SKCM	chr2	206309081	Missense_Mutation	NA	K1518I	0.38
SKCM	chr2	206308429	Missense_Mutation	novel	P1301S	0.39
SKCM	chr2	206309578	Missense_Mutation	NA	H1684Y	0.12
SKCM	chr2	206308533	Silent	NA	I1335I	0.49
SKCM	chr2	206306300	Missense_Mutation	NA	S591L	0.42
SKCM	chr2	206306343	Silent	NA	L605L	0.46
SKCM	chr2	206309953	Missense_Mutation	NA	E1809K	0.49
SKCM	chr2	206305427	Missense_Mutation	NA	V300G	0.42
SKCM	chr2	206307398	Missense_Mutation	NA	S957N	0.24
SKCM	chr2	206305305	Silent	novel	R259R	0.29
SKCM	chr2	206310447	Silent	NA	S1973S	0.36
SKCM	chr2	206305396	Missense_Mutation	NA	E290K	0.35
SKCM	chr2	206310919	Missense_Mutation	novel	E2131K	0.43
SKCM	chr2	206306426	Missense_Mutation	NA	G633E	0.31
SKCM	chr2	206307190	Missense_Mutation	NA	E888K	0.4
SKCM	chr2	206310640	Missense_Mutation	NA	D2038N	0.46
SKCM	chr2	206310038	Missense_Mutation	novel	R1837K	0.48
SKCM	chr2	206310274	Missense_Mutation	novel	P1916S	0.09
SKCM	chr2	206308731	Silent	NA	K1401K	0.32
STAD	chr2	206310518	Missense_Mutation	novel	T1997I	0.39
STAD	chr2	206309704	Frame_Shift_Del	rs745875253	*K1728Nfs5**	0.36
STAD	chr2	206310145	Frame_Shift_Del	rs770232797	*K1875Rfs39**	0.4
STAD	chr2	206306796	Silent	rs763427850	P756P	0.09
STAD	chr2	206306232	Silent	NA	T568T	0.64
STAD	chr2	206309704	Frame_Shift_Del	rs745875253	*K1728Nfs5**	0.45
STAD	chr2	206309105	Missense_Mutation	novel	V1526A	0.18
STAD	chr2	206308221	Silent	rs373408581	T1231T	0.32
STAD	chr2	206309579	Missense_Mutation	NA	H1684R	0.36
STAD	chr2	206309664	Silent	novel	F1712F	0.61
STAD	chr2	206309460	Silent	NA	D1644D	0.39
STAD	chr2	206309704	Frame_Shift_Del	rs745875253	*K1728Nfs5**	0.47
STAD	chr2	206306355	Missense_Mutation	NA	Q609H	0.32
STAD	chr2	206308075	Nonsense_Mutation	NA	E1183*	0.19
STAD	chr2	206309597	Missense_Mutation	rs757506025	R1690Q	0.61
STAD	chr2	206307835	Missense_Mutation	novel	G1103S	0.1
STAD	chr2	206309555	Missense_Mutation	rs377727867	T1676M	0.15
STAD	chr2	206309704	Frame_Shift_Del	rs745875253	*K1728Nfs5**	0.42
STAD	chr2	206306483	Missense_Mutation	NA	K652T	0.22
STAD	chr2	206307206	Missense_Mutation	NA	K893R	0.28
STAD	chr2	206308224	Missense_Mutation	NA	E1232D	0.21
STAD	chr2	206306283	Silent	NA	C585C	0.2
STAD	chr2	206306418	Silent	NA	V630V	0.34
STAD	chr2	206310353	Missense_Mutation	NA	I1942S	0.09
STAD	chr2	206306357	Missense_Mutation	rs776137882	V610A	0.17
STAD	chr2	206309704	Frame_Shift_Del	rs745875253	*K1728Nfs5**	0.32
STAD	chr2	206311211	Missense_Mutation	rs781279011	S2228L	0.3
STAD	chr2	206307841	Frame_Shift_Del	novel	*N1106Ifs11**	0.41
STAD	chr2	206304782	Missense_Mutation	NA	A85D	0.23
STAD	chr2	206309704	Frame_Shift_Del	rs745875253	*K1728Nfs5**	0.3
STAD	chr2	206309555	Missense_Mutation	rs377727867	T1676M	0.3
STAD	chr2	206306073	Missense_Mutation	NA	E515D	0.09
STAD	chr2	206308119	Silent	NA	S1197S	0.09
STAD	chr2	206305585	Missense_Mutation	novel	F353V	0.6
STAD	chr2	206309704	Frame_Shift_Del	rs745875253	*K1728Nfs5**	0.38
STAD	chr2	206305407	Silent	novel	G293G	0.5
STAD	chr2	206307802	Frame_Shift_Del	NA	I1094*	0.28
STAD	chr2	206309550	Silent	novel	H1674H	0.13
STAD	chr2	206306205	Missense_Mutation	NA	E559D	0.63
STAD	chr2	206310263	Missense_Mutation	NA	A1912V	0.44
STAD	chr2	206311102	Frame_Shift_Del	novel	*K2193Rfs57**	0.35
STAD	chr2	206307802	Frame_Shift_Del	NA	I1094*	0.19
STAD	chr2	206308454	Missense_Mutation	NA	L1309P	0.21
STAD	chr2	206307540	Silent	NA	S1004S	0.17
STAD	chr2	206305832	Missense_Mutation	rs769572660	R435H	0.19
STAD	chr2	206311175	Missense_Mutation	rs199913989	R2216Q	0.08
STAD	chr2	206309704	Frame_Shift_Del	NA	*K1728Tfs7**	0.33
THCA	chr2	206308005	In_Frame_Ins	novel	E1159_M1160insSKV	0.08
THCA	chr2	206304838	Missense_Mutation	rs779996852	E104K	0.33
THYM	chr2	206306875	Missense_Mutation	novel	C783R	0.12
THYM	chr2	206309704	Frame_Shift_Del	rs745875253	*K1728Nfs5**	0.2
UCEC	chr2	206305521	Silent	NA	E331E	0.31
UCEC	chr2	206305717	Missense_Mutation	NA	D397Y	0.26
UCEC	chr2	206305294	Nonsense_Mutation	NA	E256*	0.22
UCEC	chr2	206311314	Silent	rs762226283	A2262A	0.33
UCEC	chr2	206311315	Missense_Mutation	NA	K2263Q	0.32
UCEC	chr2	206297268	Missense_Mutation	novel	R28M	0.3
UCEC	chr2	206304855	Missense_Mutation	novel	E109D	0.14
UCEC	chr2	206307413	Missense_Mutation	novel	V962A	0.3
UCEC	chr2	206308444	Nonsense_Mutation	novel	E1306*	0.29
UCEC	chr2	206305222	Missense_Mutation	NA	D232Y	0.4
UCEC	chr2	206309203	Missense_Mutation	NA	D1559Y	0.35
UCEC	chr2	206311050	Missense_Mutation	NA	K2174N	0.58
UCEC	chr2	206311238	Missense_Mutation	NA	R2237I	0.42
UCEC	chr2	206305141	Missense_Mutation	rs781513801	T205A	0.42
UCEC	chr2	206308438	Missense_Mutation	novel	N1304D	0.45
UCEC	chr2	206309633	Missense_Mutation	novel	S1702N	0.17
UCEC	chr2	206309823	Missense_Mutation	novel	E1765D	0.56
UCEC	chr2	206310080	Missense_Mutation	novel	R1851K	0.24
UCEC	chr2	206309704	Frame_Shift_Del	rs745875253	*K1728Nfs5**	0.79
UCEC	chr2	206306591	Missense_Mutation	novel	Q688R	0.29
UCEC	chr2	206305668	Missense_Mutation	NA	E380D	0.44
UCEC	chr2	206308186	Nonsense_Mutation	NA	E1220*	0.51
UCEC	chr2	206310130	Missense_Mutation	NA	V1868F	0.47
UCEC	chr2	206310477	Missense_Mutation	NA	K1983N	0.48
UCEC	chr2	206309198	Missense_Mutation	novel	V1557A	0.41
UCEC	chr2	206309482	Missense_Mutation	novel	D1652N	0.5
UCEC	chr2	206306840	Frame_Shift_Ins	novel	*E773Rfs5**	0.27
UCEC	chr2	206310768	Missense_Mutation	novel	K2080N	0.34
UCEC	chr2	206310959	Missense_Mutation	rs764750291	R2144I	0.2
UCEC	chr2	206308414	Missense_Mutation	rs190838042	V1296I	0.4
UCEC	chr2	206309470	Missense_Mutation	novel	V1648M	0.43
UCEC	chr2	206309556	Silent	rs773055987	T1676T	0.34
UCEC	chr2	206311142	Missense_Mutation	novel	R2205I	0.42
UCEC	chr2	206305859	Missense_Mutation	novel	K444T	0.32
UCEC	chr2	206308003	Nonsense_Mutation	rs753037427	E1159*	0.17
UCEC	chr2	206309339	Missense_Mutation	novel	I1604K	0.28
UCEC	chr2	206310300	Missense_Mutation	novel	E1924D	0.24
UCEC	chr2	206311050	Missense_Mutation	NA	K2174N	0.22
UCEC	chr2	206311321	Missense_Mutation	novel	T2265P	0.17
UCEC	chr2	206306986	Missense_Mutation	NA	K820E	0.39
UCEC	chr2	206311126	Missense_Mutation	NA	L2200I	0.29
UCEC	chr2	206305939	Nonsense_Mutation	NA	E471*	0.32
UCEC	chr2	206310690	Silent	NA	E2054E	0.38
UCEC	chr2	206309004	Missense_Mutation	novel	Q1492H	0.07
UCEC	chr2	206311381	Missense_Mutation	rs781164791	A2285T	0.24
UCEC	chr2	206311590	Frame_Shift_Ins	novel	2355Rfs13	0.14
UCEC	chr2	206311590	Frame_Shift_Ins	novel	2355Rfs13	0.12
UCEC	chr2	206311592	Frame_Shift_Ins	novel	*2355Y	0.04
UCEC	chr2	206306425	Nonsense_Mutation	novel	*E638Cfs4**	0.08
UCEC	chr2	206309704	Frame_Shift_Del	rs745875253	*K1728Nfs5**	0.5
UCEC	chr2	206304832	Missense_Mutation	NA	A102T	0.16
UCEC	chr2	206308704	Silent	novel	K1392K	0.16
UCEC	chr2	206310225	Silent	NA	I1899I	0.18
UCEC	chr2	206311406	Missense_Mutation	rs768713455	R2293Q	0.25
UCEC	chr2	206311590	Frame_Shift_Ins	novel	2355Rfs13	0.12
UCEC	chr2	206311592	Frame_Shift_Ins	novel	*2355Y	0.06
UCEC	chr2	206309564	Missense_Mutation	rs754685399	R1679Q	0.64
UCEC	chr2	206305679	Missense_Mutation	novel	D384G	0.11
UCEC	chr2	206307190	Nonsense_Mutation	NA	E888*	0.45
UCEC	chr2	206309564	Missense_Mutation	rs754685399	R1679Q	0.1
UCEC	chr2	206310284	Missense_Mutation	rs367788805	R1919H	0.55
UCEC	chr2	206307802	Frame_Shift_Del	NA	I1094*	0.23
UCEC	chr2	206305552	Nonsense_Mutation	novel	E342*	0.32
UCEC	chr2	206306885	Missense_Mutation	novel	D786A	0.35
UCEC	chr2	206307190	Missense_Mutation	NA	E888K	0.33
UCEC	chr2	206308836	Missense_Mutation	novel	K1436N	0.48
UCEC	chr2	206305387	Missense_Mutation	novel	K287E	0.19
UCEC	chr2	206306578	Missense_Mutation	NA	E684K	0.48
UCEC	chr2	206307941	Missense_Mutation	novel	V1138A	0.1
UCEC	chr2	206309463	Silent	novel	E1645E	0.33
UCEC	chr2	206309609	Missense_Mutation	novel	R1694I	0.47
UCEC	chr2	206308831	Nonsense_Mutation	NA	Q1435*	0.47
UCEC	chr2	206297252	Missense_Mutation	novel	F23L	0.33
UCEC	chr2	206308836	Missense_Mutation	novel	K1436N	0.23
UCEC	chr2	206309693	Missense_Mutation	rs775009737	R1722Q	0.38
UCEC	chr2	206310954	Missense_Mutation	novel	K2142N	0.4
UCEC	chr2	206297263	Missense_Mutation	novel	Q26H	0.46
UCEC	chr2	206307863	Missense_Mutation	novel	S1112I	0.33
UCEC	chr2	206308186	Nonsense_Mutation	NA	E1220*	0.37
UCEC	chr2	206308461	Silent	NA	R1311R	0.33
UCEC	chr2	206304969	Silent	NA	Q147Q	0.32
UCEC	chr2	206306428	Missense_Mutation	novel	T634A	0.14
UCEC	chr2	206308340	Missense_Mutation	novel	V1271A	0.45
UCEC	chr2	206309552	Missense_Mutation	rs749703720	R1675Q	0.32
UCEC	chr2	206311020	Silent	novel	R2164R	0.59
UCEC	chr2	206304896	Missense_Mutation	NA	K123T	0.44
UCEC	chr2	206309945	Missense_Mutation	rs751919064	D1806G	0.43
UCEC	chr2	206310211	Nonsense_Mutation	novel	E1895*	0.44
UCEC	chr2	206307119	Missense_Mutation	novel	N864S	0.34
UCEC	chr2	206306648	Missense_Mutation	NA	S707I	0.32
UCEC	chr2	206307444	Missense_Mutation	NA	E972D	0.35
UCEC	chr2	206309345	Missense_Mutation	NA	R1606Q	0.1
UCEC	chr2	206305354	Missense_Mutation	novel	K276Q	0.33
UCEC	chr2	206305512	Missense_Mutation	novel	K328N	0.25
UCEC	chr2	206306725	Nonsense_Mutation	NA	E733*	0.27
UCEC	chr2	206308863	Missense_Mutation	novel	K1445N	0.24
UCEC	chr2	206309717	Missense_Mutation	rs767824541	S1730L	0.64
UCEC	chr2	206310298	Nonsense_Mutation	novel	E1924*	0.68
UCEC	chr2	206307801	Frame_Shift_Ins	rs765952396	*I1094Nfs14**	0.41
UCEC	chr2	206311653	3'UTR	novel		0.18
UCEC	chr2	206310145	Frame_Shift_Del	rs770232797	*K1875Rfs39**	0.39
UCEC	chr2	206311589	In_Frame_Ins	novel		0.14
UCEC	chr2	206311591	Nonstop_Mutation	novel	2355Qext8	0.14
UCEC	chr2	206305799	In_Frame_Ins	novel	S424delinsRHHNQD	0.07
UCEC	chr2	206304887	Missense_Mutation	novel	R120I	0.13
UCEC	chr2	206304990	Missense_Mutation	novel	K154N	0.43
UCEC	chr2	206305486	Nonsense_Mutation	novel	G320*	0.18
UCEC	chr2	206307802	Frame_Shift_Del	NA	I1094*	0.27
UCEC	chr2	206308453	Missense_Mutation	novel	L1309I	0.41
UCEC	chr2	206309717	Missense_Mutation	rs767824541	S1730L	0.23
UCEC	chr2	206310795	Silent	novel	N2089N	0.21
UCEC	chr2	206311211	Missense_Mutation	rs781279011	S2228L	0.17
UCEC	chr2	206306702	Missense_Mutation	novel	A725V	0.13
UCEC	chr2	206306704	Missense_Mutation	novel	L726V	0.13
UCEC	chr2	206311584	Missense_Mutation	novel	E2352D	0.38
UCEC	chr2	206309734	Missense_Mutation	novel	D1736Y	0.33
UCEC	chr2	206305344	Nonsense_Mutation	novel	W272*	0.42
UCEC	chr2	206305512	Missense_Mutation	novel	K328N	0.39
UCEC	chr2	206305514	Missense_Mutation	novel	N329S	0.41
UCEC	chr2	206306327	Missense_Mutation	novel	V600A	0.44
UCEC	chr2	206309198	Missense_Mutation	novel	V1557A	0.45
UCEC	chr2	206310635	Missense_Mutation	novel	D2036A	0.4
UCEC	chr2	206297245	Splice_Site	NA	X21_splice	0.31
UCEC	chr2	206304793	Nonsense_Mutation	NA	E89*	0.2
UCEC	chr2	206305387	Missense_Mutation	NA	K287Q	0.33
UCEC	chr2	206309556	Silent	rs773055987	T1676T	0.23
UCEC	chr2	206310959	Missense_Mutation	rs764750291	R2144I	0.25
UCEC	chr2	206305292	Missense_Mutation	novel	K255T	0.1
UCEC	chr2	206311406	Missense_Mutation	rs768713455	R2293Q	0.45
UCEC	chr2	206305492	Missense_Mutation	novel	F322I	0.26
UCEC	chr2	206309841	Silent	rs200714906	H1771H	0.36
UCEC	chr2	206310843	Silent	rs754381621	A2105A	0.31
UCEC	chr2	206311582	Missense_Mutation	novel	E2352K	0.28
UCEC	chr2	206305655	Missense_Mutation	NA	D376G	0.75
UCEC	chr2	206297353	Silent	novel	P56P	0.32
UCEC	chr2	206310144	Frame_Shift_Ins	rs773716487	*V1876Gfs5**	0.39
UCEC	chr2	206310322	Missense_Mutation	NA	R1932C	0.29
UCEC	chr2	206305799	Nonsense_Mutation	novel	*S424delinsRHHNQDVLHYWV**	0.07
UCEC	chr2	206306557	Missense_Mutation	novel	A677T	0.36
UCEC	chr2	206306494	Missense_Mutation	novel	L656I	0.13
UCEC	chr2	206309843	Missense_Mutation	novel	P1772H	0.36
UCEC	chr2	206311411	Missense_Mutation	novel	V2295M	0.17
UCEC	chr2	206310601	Missense_Mutation	novel	L2025I	0.43
UCEC	chr2	206306374	Nonsense_Mutation	novel	K616delinsIYYS*	0.16
UCEC	chr2	206308320	Frame_Shift_Ins	novel	*S1265Dfs2**	0.2
UCEC	chr2	206310959	Missense_Mutation	rs764750291	R2144I	0.16
UCEC	chr2	206311700	3'UTR	novel		0.58
UCEC	chr2	206304772	Silent	novel	L82L	0.56
UCEC	chr2	206305122	Silent	NA	R198R	0.29
UCEC	chr2	206308687	Nonsense_Mutation	NA	E1387*	0.25
UCEC	chr2	206308907	Missense_Mutation	NA	V1460A	0.18
UCEC	chr2	206311126	Missense_Mutation	NA	L2200I	0.25
UCEC	chr2	206311048	In_Frame_Del	novel	K2174_K2179del	0.05
UCEC	chr2	206304969	Silent	NA	Q147Q	0.41
UCEC	chr2	206308687	Nonsense_Mutation	NA	E1387*	0.24
UCEC	chr2	206309206	Missense_Mutation	NA	I1560V	0.21
UCEC	chr2	206311155	Missense_Mutation	NA	E2209D	0.53
UCEC	chr2	206311590	Frame_Shift_Ins	novel	2355Rfs13	0.18
UCEC	chr2	206311592	Frame_Shift_Ins	novel	*2355Y	0.05
UCEC	chr2	206305552	Nonsense_Mutation	novel	E342*	0.24
UCEC	chr2	206309718	Silent	rs140337696	S1730S	0.27
UCEC	chr2	206305708	Missense_Mutation	novel	D394N	0.24
UCEC	chr2	206307942	Silent	NA	V1138V	0.19
UCEC	chr2	206308626	Silent	novel	E1366E	0.17
UCEC	chr2	206308844	Missense_Mutation	novel	H1439P	0.11
UCEC	chr2	206308951	Nonsense_Mutation	novel	E1475*	0.44
UCEC	chr2	206310284	Missense_Mutation	rs367788805	R1919H	0.41
UCEC	chr2	206311314	Silent	rs762226283	A2262A	0.46
UCEC	chr2	206304912	Silent	rs143619911	T128T	0.45
UCEC	chr2	206305186	Missense_Mutation	NA	D220N	0.39
UCEC	chr2	206308444	Nonsense_Mutation	novel	E1306*	0.35
UCEC	chr2	206308819	Nonsense_Mutation	novel	E1431*	0.28
UCEC	chr2	206311095	Silent	novel	G2189G	0.42
UCEC	chr2	206309717	Missense_Mutation	rs767824541	S1730L	0.19
UCEC	chr2	206309704	Frame_Shift_Del	rs745875253	*K1728Nfs5**	0.41
UCEC	chr2	206306426	Missense_Mutation	NA	G633E	0.39
UCEC	chr2	206306374	Frame_Shift_Ins	novel	*K616Ifs36**	0.1
UCEC	chr2	206306376	Missense_Mutation	novel	K616N	0.01
UCEC	chr2	206305117	Missense_Mutation	NA	D197N	0.34
UCEC	chr2	206305702	Nonsense_Mutation	novel	Q392*	0.28
UCEC	chr2	206308444	Nonsense_Mutation	novel	E1306*	0.31
UCS	chr2	206311241	Missense_Mutation	novel	Y2238F	0.43
UCS	chr2	206305939	Nonsense_Mutation	NA	E471*	0.27
UCS	chr2	206308687	Nonsense_Mutation	NA	E1387*	0.4
UCS	chr2	206309832	Missense_Mutation	novel	K1768N	0.32
UCS	chr2	206308510	Missense_Mutation	novel	E1328Q	0.11

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
MESO	DEL	0.092	0.014499
PAAD	AMP	0.0761	0.1091
PAAD	DEL	0.0326	0.2014

Survival Analysis

Cancer	P-value	Q-value
PRAD	0.028	Kaplan-Meier Survival Analysis
ESCA	0.031	Kaplan-Meier Survival Analysis
KIRP	0.013	Kaplan-Meier Survival Analysis
PAAD	0.046	Kaplan-Meier Survival Analysis
UCEC	0.026	Kaplan-Meier Survival Analysis
DLBC	0.0027	Kaplan-Meier Survival Analysis
LGG	0.049	Kaplan-Meier Survival Analysis