EuRBPDB

Description

Ensembl ID: ENSG00000204316 (Gene tree)
Gene ID: 64978
Gene Symbol: MRPL38
Alias: RPML3|MRP-L3|HSPC262|MGC4810
Full Name: mitochondrial ribosomal protein L38
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 6,771 bases
Position: chr17:75,898,643-75,905,413
Accession: 14033
RBP type: non-canonical RBP
Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000588620	MRPL38-217	498	-	-	- (aa)	-	-
ENST00000483393	MRPL38-211	525	-	-	- (aa)	-	-
ENST00000410030	MRPL38-202	535	-	-	- (aa)	-	-
ENST00000474548	MRPL38-206	529	-	-	- (aa)	-	-
ENST00000480203	MRPL38-210	534	-	-	- (aa)	-	-
ENST00000585475	MRPL38-216	580	-	-	- (aa)	-	-
ENST00000477736	MRPL38-209	843	-	-	- (aa)	-	-
ENST00000493104	MRPL38-213	1116	-	-	- (aa)	-	-
ENST00000493383	MRPL38-214	727	-	-	- (aa)	-	-
ENST00000486101	MRPL38-212	767	-	-	- (aa)	-	-
ENST00000309352	MRPL38-201	1888	-	ENSP00000308275	380 (aa)	-	Q96DV4
ENST00000477371	MRPL38-208	566	-	-	- (aa)	-	-
ENST00000464758	MRPL38-204	752	-	-	- (aa)	-	-
ENST00000471434	MRPL38-205	550	-	-	- (aa)	-	-
ENST00000494179	MRPL38-215	870	-	-	- (aa)	-	-
ENST00000477023	MRPL38-207	446	-	-	- (aa)	-	-
ENST00000461602	MRPL38-203	880	-	-	- (aa)	-	-

Gene Model

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000204316	MRPL38	76	41.000	FBgn0030552	mRpL38	72	41.000	Drosophila_melanogaster

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005739	mitochondrion	28892042.	IDA	Component
GO:0005743	mitochondrial inner membrane	-	TAS	Component
GO:0005762	mitochondrial large ribosomal subunit	21873635.	IBA	Component
GO:0005762	mitochondrial large ribosomal subunit	25278503.28892042.	IDA	Component
GO:0070125	mitochondrial translational elongation	-	TAS	Process
GO:0070126	mitochondrial translational termination	-	TAS	Process