EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000204351 (Gene tree)
Gene ID: 6499
Gene Symbol: SKIV2L
Alias: HLP|DDX13|SKI2W|170A|SKIV2L1|SKIV2
Full Name: Ski2 like RNA helicase
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 10,952 bases
Position: chr6:31,958,804-31,969,755
Accession: 10898
RBP type: canonical RBP
Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a human homologue of yeast SKI2 and may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs. This gene is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000364543	rRNA_proc-arch	PF13234.6	5e-41	1	1
ENSP00000364543	DEAD	PF00270.29	1.3e-15	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
19556007	Role of RDBP and SKIV2L variants in the major histocompatibility complex class III region in polypoidal choroidal vasculopathy etiology.	Ophthalmology	2009 Aug	Kondo N	doi: 10.1016/j.ophtha.2009.03.004
22114319	The crystal structure of S. cerevisiae Ski2, a DExH helicase associated with the cytoplasmic functions of the exosome.	RNA	2012 Jan	Halbach F	doi: 10.1261/rna.029553.111
23953113	The yeast ski complex: crystal structure and RNA channeling to the exosome complex.	Cell	2013 Aug 15	Halbach F	doi: 10.1016/j.cell.2013.07.017.
23704370	Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8.	Science	2013 Jul 5	Mozaffari-Jovin S	doi: 10.1126/science.1237515
20572981	Genomic plus-strand RNA synthesis by the brome mosaic virus (BMV) RNA replicase requires a sequence that is complementary to the binding site of the BMV helicase-like protein.	Mol Plant Pathol	2000 Nov 1	Sivakumaran K	doi: 10.1046/j.1364-3703.2000.00037.x.
30972737	Domain structure of HelD, an interaction partner of Bacillus subtilis RNA polymerase.	FEBS Lett	2019 May	Koval T	doi: 10.1002/1873-3468.13385

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000474839	SKIV2L-208	3378	-	ENSP00000420470	69 (aa)	-	F8WDE8
ENST00000494058	SKIV2L-215	867	-	-	- (aa)	-	-
ENST00000488648	SKIV2L-212	720	-	-	- (aa)	-	-
ENST00000466290	SKIV2L-205	583	-	-	- (aa)	-	-
ENST00000461915	SKIV2L-203	691	-	-	- (aa)	-	-
ENST00000492900	SKIV2L-214	686	-	-	- (aa)	-	-
ENST00000465703	SKIV2L-204	4507	-	-	- (aa)	-	-
ENST00000491994	SKIV2L-213	866	-	ENSP00000417586	182 (aa)	-	H7C4L3
ENST00000471818	SKIV2L-207	706	-	-	- (aa)	-	-
ENST00000485349	SKIV2L-211	734	-	-	- (aa)	-	-
ENST00000375394	SKIV2L-201	3894	XM_011514815	ENSP00000364543	1246 (aa)	XP_011513117	Q15477
ENST00000483553	SKIV2L-209	1307	-	ENSP00000420332	156 (aa)	-	H7C5N0
ENST00000461073	SKIV2L-202	1157	-	ENSP00000419905	230 (aa)	-	B4E0B4
ENST00000470453	SKIV2L-206	455	-	-	- (aa)	-	-
ENST00000628157	SKIV2L-216	210	-	ENSP00000485707	69 (aa)	-	F8WDE8
ENST00000484835	SKIV2L-210	931	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000204351's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03018	RNA degradation	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000204351	Macular Degeneration	2.629224E-6	-
ENSG00000204351	Macular Degeneration	1.368E-5	-
ENSG00000204351	Lupus Erythematosus, Systemic	8.61E-6	18204446
ENSG00000204351	Macular Degeneration	5.68E-9	-
ENSG00000204351	Macular Degeneration	1.29E-22	-
ENSG00000204351	Macular Degeneration	5.68E-19	-
ENSG00000204351	Macular Degeneration	5.48E-9	-
ENSG00000204351	Macular Degeneration	5.99E-9	-
ENSG00000204351	Macular Degeneration	1.636E-08	20385819
ENSG00000204351	Macular Degeneration	2.03E-21	20385819
ENSG00000204351	Macular Degeneration	4.889E-18	20385819
ENSG00000204351	Macular Degeneration	1.575E-08	20385819
ENSG00000204351	Macular Degeneration	2.129E-08	20385819
ENSG00000204351	Macular Degeneration	4.342E-05	20385819
ENSG00000204351	Neuroblastoma	3.78e-005	23222812
ENSG00000204351	Neutrophils	4.5210000E-006	21738480
ENSG00000204351	Metabolism	7E-13	24816252
ENSG00000204351	Body Height	2E-8	25281659
ENSG00000204351	Immunoglobulins	4E-6	23382691
ENSG00000204351	Macular Degeneration	3E-21	20385819
ENSG00000204351	Macular Degeneration	7E-7	23577725
ENSG00000204351	Macular Degeneration	4E-89	23455636
ENSG00000204351	Immunoglobulins	9E-6	23382691
ENSG00000204351	Macular Degeneration	5E-15	20861866

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000204351	rs9296004	6	31966200	C	Blood protein levels	29875488	[0.51-0.71] unit increase	0.61	EFO_0007937
ENSG00000204351	rs429608	6	31962685	G	Age-related macular degeneration	23455636	[1.68-1.79]	1.74	EFO_0001365
ENSG00000204351	rs116503776	6	31962685	?	Advanced age-related macular degeneration	26691988		1.754386	EFO_1001492\|EFO_0001365\|EFO_0004683
ENSG00000204351	rs592229	6	31962664	G	Infant length	25281659	[0.030-0.066] unit increase	0.048	EFO_0006785
ENSG00000204351	rs592229	6	31962664	G	IgG glycosylation	23382691	[0.083-0.213] unit increase	0.1479	EFO_0005193
ENSG00000204351	rs592229	6	31962664	G	IgG glycosylation	23382691	[0.088-0.219] unit increase	0.1536	EFO_0005193
ENSG00000204351	rs429608	6	31962685	G	Age-related macular degeneration	20385819	[1.84-2.53]	2.16	EFO_0001365
ENSG00000204351	rs2734331	6	31962574	A	Blood metabolite levels	24816252	[0.053-0.093] unit increase	0.073	EFO_0005664
ENSG00000204351	rs406936	6	31965384	?	Age-related macular degeneration	23577725	[1.41-2.17]	1.75	EFO_0001365
ENSG00000204351	rs2280774	6	31960914	A	Blood protein levels	28240269	[0.22-0.39] unit decrease	0.3064	EFO_0008140
ENSG00000204351	rs2280774	6	31960914	A	Blood protein levels	28240269	[0.42-0.59] unit decrease	0.5048	EFO_0008092
ENSG00000204351	rs116503776	6	31962685	G	Disease progression in age-related macular degeneration	29346644		1.79	EFO_0001365\|EFO_0008336
ENSG00000204351	rs34241101	6	31968280	?	Strep throat	28928442	[0.034-0.076] unit increase	0.0548	EFO_0008408
ENSG00000204351	rs35664695	6	31962031	?	Tonsillectomy	28928442	[0.14-0.22] unit increase	0.1764	EFO_0007924
ENSG00000204351	rs401775	6	31963360	?	Plantar warts	28928442	[0.079-0.141] unit increase	0.1102	EFO_0008406
ENSG00000204351	rs429608	6	31962685	?	Age-related macular degeneration	20861866	[NR]	1.85	EFO_0001365
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.52100945	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.39637592	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.3802861	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.33613363	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.32579833	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.31686857	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.28144673	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.28027427	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.26399913	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.25580245	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.24417928	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.24409658	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.24099603	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.2377962	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.23302191	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.23818818	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.23244344	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.22689201	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.22482824	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.22585352	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.22485517	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.22256884	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.22226523	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.22065759	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit increase	0.21843159	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.2177297	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.22229372	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.22150208	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.21950717	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.21838582	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.21669233	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.21747725	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.21559419	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.21315299	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.21168913	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.21163373	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.20879674	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.21148543	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.21330081	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.2137869	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.21210562	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit increase	0.2171866	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.20827559	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.21070449	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit increase	0.21166307	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.20376533	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.20342621	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.19908749	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.20074438	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.20123966	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.19879499	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.19901367	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.19949478	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.20122391	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.19831412	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.19853744	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.1949626	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.19830309	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.19258557	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.19629622	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.1949712	EFO_0007937
ENSG00000204351	rs115566560	6	31964400	C	Blood protein levels	30072576	[NR] unit decrease	0.19306628	EFO_0007937
ENSG00000204351	rs114212579	6	31968280	?	Psoriatic arthritis	30552173	[NR] z-score increase	7.56	EFO_0003778

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000204351's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000204351	SKIV2L	90	31.928	ENSG00000039123	MTREX	91	36.166

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000204351	SKIV2L	99	61.349	ENSAPOG00000008257	skiv2l	99	61.767	Acanthochromis_polyacanthus
ENSG00000204351	SKIV2L	100	94.783	ENSAMEG00000002078	SKIV2L	100	94.783	Ailuropoda_melanoleuca
ENSG00000204351	SKIV2L	99	59.888	ENSACIG00000016719	skiv2l	99	60.355	Amphilophus_citrinellus
ENSG00000204351	SKIV2L	99	61.142	ENSAOCG00000017352	skiv2l	99	61.415	Amphiprion_ocellaris
ENSG00000204351	SKIV2L	99	60.983	ENSAPEG00000001055	skiv2l	99	61.415	Amphiprion_percula
ENSG00000204351	SKIV2L	99	61.018	ENSATEG00000007601	skiv2l	99	61.075	Anabas_testudineus
ENSG00000204351	SKIV2L	99	65.176	ENSACAG00000011746	SKIV2L	99	65.976	Anolis_carolinensis
ENSG00000204351	SKIV2L	100	97.592	ENSANAG00000037992	SKIV2L	100	97.592	Aotus_nancymaae
ENSG00000204351	SKIV2L	99	61.569	ENSACLG00000006886	skiv2l	99	61.687	Astatotilapia_calliptera
ENSG00000204351	SKIV2L	98	59.268	ENSAMXG00000011517	skiv2l	99	59.348	Astyanax_mexicanus
ENSG00000204351	SKIV2L	100	94.703	ENSBTAG00000005587	SKIV2L	100	94.703	Bos_taurus
ENSG00000204351	SKIV2L	96	39.781	WBGene00008502	skih-2	99	39.814	Caenorhabditis_elegans
ENSG00000204351	SKIV2L	100	97.432	ENSCJAG00000002263	SKIV2L	100	97.432	Callithrix_jacchus
ENSG00000204351	SKIV2L	100	94.623	ENSCAFG00000000679	SKIV2L	100	94.623	Canis_familiaris
ENSG00000204351	SKIV2L	100	94.543	ENSCAFG00020000948	SKIV2L	100	94.543	Canis_lupus_dingo
ENSG00000204351	SKIV2L	100	94.703	ENSCHIG00000012897	SKIV2L	100	94.703	Capra_hircus
ENSG00000204351	SKIV2L	100	94.703	ENSTSYG00000012133	SKIV2L	100	94.703	Carlito_syrichta
ENSG00000204351	SKIV2L	98	94.944	ENSCPOG00000001307	SKIV2L	100	92.295	Cavia_porcellus
ENSG00000204351	SKIV2L	100	97.512	ENSCCAG00000026206	SKIV2L	100	97.512	Cebus_capucinus
ENSG00000204351	SKIV2L	100	98.395	ENSCATG00000036901	SKIV2L	100	98.395	Cercocebus_atys
ENSG00000204351	SKIV2L	98	96.067	ENSCLAG00000007678	SKIV2L	100	92.937	Chinchilla_lanigera
ENSG00000204351	SKIV2L	100	98.234	ENSCSAG00000008988	SKIV2L	100	98.234	Chlorocebus_sabaeus
ENSG00000204351	SKIV2L	87	64.912	ENSCPBG00000000343	SKIV2L	96	64.912	Chrysemys_picta_bellii
ENSG00000204351	SKIV2L	96	52.542	ENSCING00000005576	-	99	50.804	Ciona_intestinalis
ENSG00000204351	SKIV2L	99	98.554	ENSCANG00000039709	SKIV2L	100	98.554	Colobus_angolensis_palliatus
ENSG00000204351	SKIV2L	98	97.191	ENSCGRG00001008385	Skiv2l	100	93.665	Cricetulus_griseus_chok1gshd
ENSG00000204351	SKIV2L	99	61.434	ENSCSEG00000011326	skiv2l	98	61.353	Cynoglossus_semilaevis
ENSG00000204351	SKIV2L	99	61.133	ENSCVAG00000003072	skiv2l	99	61.156	Cyprinodon_variegatus
ENSG00000204351	SKIV2L	99	60.142	ENSDARG00000062206	skiv2l	99	60.320	Danio_rerio
ENSG00000204351	SKIV2L	98	94.382	ENSDNOG00000037590	SKIV2L	100	88.489	Dasypus_novemcinctus
ENSG00000204351	SKIV2L	93	43.839	FBgn0039117	tst	97	43.923	Drosophila_melanogaster
ENSG00000204351	SKIV2L	98	93.820	ENSETEG00000009522	SKIV2L	69	93.059	Echinops_telfairi
ENSG00000204351	SKIV2L	89	56.597	ENSEBUG00000013680	-	95	57.414	Eptatretus_burgeri
ENSG00000204351	SKIV2L	98	96.067	ENSEASG00005015534	SKIV2L	99	95.349	Equus_asinus_asinus
ENSG00000204351	SKIV2L	99	95.028	ENSECAG00000021823	SKIV2L	96	95.169	Equus_caballus
ENSG00000204351	SKIV2L	96	87.919	ENSEEUG00000005049	SKIV2L	57	97.628	Erinaceus_europaeus
ENSG00000204351	SKIV2L	99	60.079	ENSELUG00000000181	skiv2l	94	66.598	Esox_lucius
ENSG00000204351	SKIV2L	100	95.265	ENSFCAG00000004519	SKIV2L	100	95.265	Felis_catus
ENSG00000204351	SKIV2L	100	89.816	ENSFDAG00000009438	SKIV2L	100	90.056	Fukomys_damarensis
ENSG00000204351	SKIV2L	100	60.112	ENSFHEG00000008853	skiv2l	99	61.107	Fundulus_heteroclitus
ENSG00000204351	SKIV2L	99	59.472	ENSGMOG00000005926	skiv2l	98	59.497	Gadus_morhua
ENSG00000204351	SKIV2L	99	55.249	ENSGALG00000035499	SKIV2L	99	60.550	Gallus_gallus
ENSG00000204351	SKIV2L	99	61.155	ENSGAFG00000002382	skiv2l	99	61.347	Gambusia_affinis
ENSG00000204351	SKIV2L	99	60.079	ENSGACG00000002927	skiv2l	98	60.274	Gasterosteus_aculeatus
ENSG00000204351	SKIV2L	100	99.358	ENSGGOG00000002270	SKIV2L	100	99.358	Gorilla_gorilla
ENSG00000204351	SKIV2L	99	61.490	ENSHBUG00000000726	skiv2l	99	61.606	Haplochromis_burtoni
ENSG00000204351	SKIV2L	98	93.820	ENSHGLG00000016596	SKIV2L	100	91.506	Heterocephalus_glaber_female
ENSG00000204351	SKIV2L	100	88.622	ENSHGLG00100014161	SKIV2L	100	88.862	Heterocephalus_glaber_male
ENSG00000204351	SKIV2L	98	59.551	ENSHCOG00000007191	skiv2l	100	59.398	Hippocampus_comes
ENSG00000204351	SKIV2L	99	59.716	ENSIPUG00000016263	skiv2l	100	59.904	Ictalurus_punctatus
ENSG00000204351	SKIV2L	100	94.462	ENSSTOG00000014596	SKIV2L	100	94.462	Ictidomys_tridecemlineatus
ENSG00000204351	SKIV2L	98	53.933	ENSLACG00000002986	-	73	59.950	Latimeria_chalumnae
ENSG00000204351	SKIV2L	63	61.404	ENSLOCG00000000691	-	93	61.677	Lepisosteus_oculatus
ENSG00000204351	SKIV2L	98	96.629	ENSLAFG00000014231	SKIV2L	100	94.141	Loxodonta_africana
ENSG00000204351	SKIV2L	100	98.315	ENSMFAG00000034235	SKIV2L	100	98.315	Macaca_fascicularis
ENSG00000204351	SKIV2L	100	98.234	ENSMMUG00000000736	SKIV2L	100	98.234	Macaca_mulatta
ENSG00000204351	SKIV2L	100	98.234	ENSMNEG00000044474	SKIV2L	100	98.234	Macaca_nemestrina
ENSG00000204351	SKIV2L	100	98.475	ENSMLEG00000030512	SKIV2L	100	98.475	Mandrillus_leucophaeus
ENSG00000204351	SKIV2L	99	60.794	ENSMAMG00000002927	skiv2l	99	60.981	Mastacembelus_armatus
ENSG00000204351	SKIV2L	99	61.410	ENSMZEG00005026415	skiv2l	99	61.526	Maylandia_zebra
ENSG00000204351	SKIV2L	70	51.357	ENSMGAG00000001320	SKIV2L	97	51.357	Meleagris_gallopavo
ENSG00000204351	SKIV2L	98	97.191	ENSMAUG00000018613	Skiv2l	100	93.184	Mesocricetus_auratus
ENSG00000204351	SKIV2L	100	95.425	ENSMICG00000046331	SKIV2L	100	95.425	Microcebus_murinus
ENSG00000204351	SKIV2L	98	95.506	ENSMOCG00000014240	Skiv2l	100	91.820	Microtus_ochrogaster
ENSG00000204351	SKIV2L	99	60.932	ENSMMOG00000014547	skiv2l	98	61.007	Mola_mola
ENSG00000204351	SKIV2L	98	92.697	ENSMODG00000015052	SKIV2L	100	87.990	Monodelphis_domestica
ENSG00000204351	SKIV2L	99	59.903	ENSMALG00000010535	skiv2l	98	59.886	Monopterus_albus
ENSG00000204351	SKIV2L	98	96.067	MGP_CAROLIEiJ_G0021477	Skiv2l	100	93.184	Mus_caroli
ENSG00000204351	SKIV2L	98	96.067	ENSMUSG00000040356	Skiv2l	100	93.184	Mus_musculus
ENSG00000204351	SKIV2L	98	94.944	MGP_PahariEiJ_G0020472	Skiv2l	100	92.462	Mus_pahari
ENSG00000204351	SKIV2L	98	96.067	MGP_SPRETEiJ_G0022382	Skiv2l	100	92.943	Mus_spretus
ENSG00000204351	SKIV2L	100	94.543	ENSMPUG00000010567	SKIV2L	100	94.543	Mustela_putorius_furo
ENSG00000204351	SKIV2L	100	93.579	ENSMLUG00000000628	SKIV2L	100	93.579	Myotis_lucifugus
ENSG00000204351	SKIV2L	99	60.845	ENSNBRG00000018650	skiv2l	98	61.210	Neolamprologus_brichardi
ENSG00000204351	SKIV2L	98	100.000	ENSNLEG00000006451	SKIV2L	100	95.253	Nomascus_leucogenys
ENSG00000204351	SKIV2L	78	92.920	ENSMEUG00000006072	SKIV2L	78	92.920	Notamacropus_eugenii
ENSG00000204351	SKIV2L	100	94.061	ENSOPRG00000003972	SKIV2L	100	94.061	Ochotona_princeps
ENSG00000204351	SKIV2L	100	92.135	ENSODEG00000017516	SKIV2L	100	92.135	Octodon_degus
ENSG00000204351	SKIV2L	99	61.912	ENSONIG00000013500	skiv2l	99	62.086	Oreochromis_niloticus
ENSG00000204351	SKIV2L	100	94.864	ENSOCUG00000007019	SKIV2L	100	94.864	Oryctolagus_cuniculus
ENSG00000204351	SKIV2L	99	61.173	ENSORLG00000002021	skiv2l	99	61.365	Oryzias_latipes
ENSG00000204351	SKIV2L	99	61.014	ENSORLG00020009462	skiv2l	99	61.285	Oryzias_latipes_hni
ENSG00000204351	SKIV2L	99	60.697	ENSORLG00015016750	skiv2l	99	60.884	Oryzias_latipes_hsok
ENSG00000204351	SKIV2L	99	61.636	ENSOMEG00000008531	skiv2l	99	61.594	Oryzias_melastigma
ENSG00000204351	SKIV2L	100	94.783	ENSOGAG00000009578	SKIV2L	100	94.783	Otolemur_garnettii
ENSG00000204351	SKIV2L	100	89.115	ENSOARG00000002411	-	100	89.115	Ovis_aries
ENSG00000204351	SKIV2L	96	86.577	ENSOARG00000001720	-	70	89.399	Ovis_aries
ENSG00000204351	SKIV2L	98	100.000	ENSPPAG00000040211	SKIV2L	100	98.635	Pan_paniscus
ENSG00000204351	SKIV2L	100	95.345	ENSPPRG00000005017	SKIV2L	100	95.345	Panthera_pardus
ENSG00000204351	SKIV2L	100	94.944	ENSPTIG00000021656	SKIV2L	100	94.944	Panthera_tigris_altaica
ENSG00000204351	SKIV2L	100	99.599	ENSPTRG00000017997	SKIV2L	100	99.599	Pan_troglodytes
ENSG00000204351	SKIV2L	98	99.438	ENSPANG00000011501	SKIV2L	100	97.267	Papio_anubis
ENSG00000204351	SKIV2L	99	60.205	ENSPKIG00000011876	skiv2l	99	60.350	Paramormyrops_kingsleyae
ENSG00000204351	SKIV2L	99	60.257	ENSPMGG00000019707	skiv2l	98	60.488	Periophthalmus_magnuspinnatus
ENSG00000204351	SKIV2L	98	96.629	ENSPEMG00000019001	Skiv2l	100	93.585	Peromyscus_maniculatus_bairdii
ENSG00000204351	SKIV2L	98	92.697	ENSPCIG00000018792	SKIV2L	100	87.600	Phascolarctos_cinereus
ENSG00000204351	SKIV2L	99	61.076	ENSPFOG00000002424	skiv2l	99	61.267	Poecilia_formosa
ENSG00000204351	SKIV2L	99	61.203	ENSPLAG00000018304	skiv2l	99	61.396	Poecilia_latipinna
ENSG00000204351	SKIV2L	99	61.155	ENSPMEG00000006997	skiv2l	99	61.347	Poecilia_mexicana
ENSG00000204351	SKIV2L	99	59.646	ENSPREG00000002277	skiv2l	98	59.383	Poecilia_reticulata
ENSG00000204351	SKIV2L	100	98.716	ENSPPYG00000016472	SKIV2L	100	98.716	Pongo_abelii
ENSG00000204351	SKIV2L	97	94.350	ENSPCAG00000004178	SKIV2L	77	94.730	Procavia_capensis
ENSG00000204351	SKIV2L	100	96.308	ENSPCOG00000010308	SKIV2L	100	96.308	Propithecus_coquereli
ENSG00000204351	SKIV2L	100	93.419	ENSPVAG00000005136	SKIV2L	100	93.419	Pteropus_vampyrus
ENSG00000204351	SKIV2L	99	59.759	ENSPNYG00000017853	skiv2l	97	66.529	Pundamilia_nyererei
ENSG00000204351	SKIV2L	98	60.706	ENSPNAG00000011823	skiv2l	99	60.884	Pygocentrus_nattereri
ENSG00000204351	SKIV2L	98	95.506	ENSRNOG00000000421	Skiv2l	100	93.424	Rattus_norvegicus
ENSG00000204351	SKIV2L	98	95.628	ENSRBIG00000035485	SKIV2L	99	95.628	Rhinopithecus_bieti
ENSG00000204351	SKIV2L	100	98.395	ENSRROG00000036429	SKIV2L	100	98.395	Rhinopithecus_roxellana
ENSG00000204351	SKIV2L	93	37.530	YLR398C	-	93	37.609	Saccharomyces_cerevisiae
ENSG00000204351	SKIV2L	98	99.438	ENSSBOG00000027920	SKIV2L	100	97.432	Saimiri_boliviensis_boliviensis
ENSG00000204351	SKIV2L	98	92.135	ENSSHAG00000008963	SKIV2L	100	86.309	Sarcophilus_harrisii
ENSG00000204351	SKIV2L	99	60.787	ENSSFOG00015016930	skiv2l	99	61.133	Scleropages_formosus
ENSG00000204351	SKIV2L	99	60.974	ENSSMAG00000020185	skiv2l	99	60.995	Scophthalmus_maximus
ENSG00000204351	SKIV2L	99	61.362	ENSSDUG00000019977	skiv2l	99	61.557	Seriola_dumerili
ENSG00000204351	SKIV2L	99	60.097	ENSSLDG00000024382	skiv2l	98	60.163	Seriola_lalandi_dorsalis
ENSG00000204351	SKIV2L	99	62.248	ENSSPUG00000012945	SKIV2L	98	62.343	Sphenodon_punctatus
ENSG00000204351	SKIV2L	98	57.542	ENSSPAG00000012904	skiv2l	98	61.069	Stegastes_partitus
ENSG00000204351	SKIV2L	100	94.783	ENSSSCG00000001424	SKIV2L	100	94.783	Sus_scrofa
ENSG00000204351	SKIV2L	85	54.346	ENSTRUG00000000966	skiv2l	100	55.138	Takifugu_rubripes
ENSG00000204351	SKIV2L	99	59.841	ENSTNIG00000004382	skiv2l	98	59.919	Tetraodon_nigroviridis
ENSG00000204351	SKIV2L	98	94.382	ENSTBEG00000003462	SKIV2L	94	93.374	Tupaia_belangeri
ENSG00000204351	SKIV2L	98	95.506	ENSTTRG00000005931	SKIV2L	100	89.727	Tursiops_truncatus
ENSG00000204351	SKIV2L	100	95.265	ENSUAMG00000024336	SKIV2L	100	95.265	Ursus_americanus
ENSG00000204351	SKIV2L	98	94.382	ENSUMAG00000012666	SKIV2L	99	95.435	Ursus_maritimus
ENSG00000204351	SKIV2L	98	95.506	ENSVVUG00000022807	SKIV2L	98	94.947	Vulpes_vulpes
ENSG00000204351	SKIV2L	100	58.016	ENSXETG00000010932	skiv2l	100	58.287	Xenopus_tropicalis
ENSG00000204351	SKIV2L	99	61.329	ENSXCOG00000019517	skiv2l	96	61.408	Xiphophorus_couchianus
ENSG00000204351	SKIV2L	99	60.728	ENSXMAG00000014079	skiv2l	99	60.915	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	-	IEA	Function
GO:0004004	ATP-dependent RNA helicase activity	21873635.	IBA	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	-	IEA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006401	RNA catabolic process	21873635.	IBA	Process
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	-	TAS	Process
GO:0055087	Ski complex	21873635.	IBA	Component
GO:0055087	Ski complex	16024656.	IDA	Component
GO:0070478	nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay	21873635.	IBA	Process