EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000204590 (Gene tree)
Gene ID: 2794
Gene Symbol: GNL1
Alias: HSR1
Full Name: G protein nucleolar 1 (putative)
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 16,218 bases
Position: chr6:30,541,377-30,557,594
Accession: 4413
RBP type: canonical RBP
Summary: The GNL1 gene, identified in the human major histocompatibility complex class I region, shows a high degree of similarity with its mouse counterpart. The GNL1 gene is located less than 2 kb centromeric to HLA-E, in the same transcriptional orientation. GNL1 is telomeric to HLA-B and HLA-C. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000365806	MMR_HSR1	PF01926.23	6.5e-13	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000462708	GNL1-203	774	-	-	- (aa)	-	-
ENST00000433809	GNL1-202	1093	-	ENSP00000404728	264 (aa)	-	A2AB27
ENST00000487166	GNL1-205	522	-	-	- (aa)	-	-
ENST00000376621	GNL1-201	7490	XM_005249015	ENSP00000365806	607 (aa)	XP_005249072	P36915
ENST00000464231	GNL1-204	545	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000204590's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000204590	rs2524222	6	30543393	T	Major depressive disorder	27479909	[0.02-0.047] unit increase	0.0335	EFO_0003761

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000204590's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000204590	GNL1	96	57.504	ENSAPOG00000006315	gnl1	88	58.559	Acanthochromis_polyacanthus
ENSG00000204590	GNL1	100	98.023	ENSAMEG00000013421	GNL1	100	98.023	Ailuropoda_melanoleuca
ENSG00000204590	GNL1	96	57.797	ENSACIG00000013539	gnl1	89	59.058	Amphilophus_citrinellus
ENSG00000204590	GNL1	96	57.673	ENSAOCG00000008320	gnl1	88	58.739	Amphiprion_ocellaris
ENSG00000204590	GNL1	96	57.673	ENSAPEG00000011154	gnl1	88	58.739	Amphiprion_percula
ENSG00000204590	GNL1	90	59.892	ENSATEG00000020647	gnl1	89	59.099	Anabas_testudineus
ENSG00000204590	GNL1	100	64.603	ENSACAG00000010395	GNL1	100	66.190	Anolis_carolinensis
ENSG00000204590	GNL1	100	98.686	ENSANAG00000028106	GNL1	100	98.686	Aotus_nancymaae
ENSG00000204590	GNL1	96	58.136	ENSACLG00000025394	gnl1	88	59.601	Astatotilapia_calliptera
ENSG00000204590	GNL1	92	58.140	ENSAMXG00000016080	gnl1	91	58.484	Astyanax_mexicanus
ENSG00000204590	GNL1	100	98.023	ENSBTAG00000025516	GNL1	100	98.023	Bos_taurus
ENSG00000204590	GNL1	100	98.358	ENSCJAG00000019996	GNL1	100	98.358	Callithrix_jacchus
ENSG00000204590	GNL1	100	97.694	ENSCAFG00000000396	GNL1	100	97.694	Canis_familiaris
ENSG00000204590	GNL1	100	97.694	ENSCAFG00020017556	GNL1	100	97.694	Canis_lupus_dingo
ENSG00000204590	GNL1	100	97.694	ENSCHIG00000019763	GNL1	100	97.694	Capra_hircus
ENSG00000204590	GNL1	100	98.517	ENSTSYG00000000164	GNL1	100	98.517	Carlito_syrichta
ENSG00000204590	GNL1	88	90.858	ENSCAPG00000006662	GNL1	98	89.925	Cavia_aperea
ENSG00000204590	GNL1	100	91.118	ENSCPOG00000001944	GNL1	100	90.625	Cavia_porcellus
ENSG00000204590	GNL1	100	99.176	ENSCCAG00000037467	GNL1	100	99.176	Cebus_capucinus
ENSG00000204590	GNL1	100	99.176	ENSCATG00000045232	GNL1	100	99.176	Cercocebus_atys
ENSG00000204590	GNL1	96	93.127	ENSCLAG00000012557	GNL1	100	93.127	Chinchilla_lanigera
ENSG00000204590	GNL1	100	99.012	ENSCSAG00000008202	GNL1	100	99.012	Chlorocebus_sabaeus
ENSG00000204590	GNL1	87	93.333	ENSCHOG00000010907	GNL1	87	90.476	Choloepus_hoffmanni
ENSG00000204590	GNL1	89	71.376	ENSCPBG00000018821	GNL1	100	67.302	Chrysemys_picta_bellii
ENSG00000204590	GNL1	89	51.465	ENSCING00000014499	-	100	49.457	Ciona_intestinalis
ENSG00000204590	GNL1	93	50.266	ENSCSAVG00000007354	-	90	49.816	Ciona_savignyi
ENSG00000204590	GNL1	100	99.012	ENSCANG00000012933	GNL1	100	99.012	Colobus_angolensis_palliatus
ENSG00000204590	GNL1	100	95.559	ENSCGRG00001004986	Gnl1	100	95.066	Cricetulus_griseus_chok1gshd
ENSG00000204590	GNL1	96	95.369	ENSCGRG00000014309	Gnl1	100	94.854	Cricetulus_griseus_crigri
ENSG00000204590	GNL1	91	51.060	ENSCSEG00000019714	gnl1	95	50.255	Cynoglossus_semilaevis
ENSG00000204590	GNL1	92	58.275	ENSCVAG00000022650	gnl1	89	58.244	Cyprinodon_variegatus
ENSG00000204590	GNL1	90	59.279	ENSDARG00000061789	gnl1	99	55.447	Danio_rerio
ENSG00000204590	GNL1	92	94.215	ENSDNOG00000041571	GNL1	100	78.033	Dasypus_novemcinctus
ENSG00000204590	GNL1	99	41.842	FBgn0032882	Ns4	83	44.311	Drosophila_melanogaster
ENSG00000204590	GNL1	51	93.930	ENSETEG00000005518	-	100	93.610	Echinops_telfairi
ENSG00000204590	GNL1	56	54.348	ENSEBUG00000009531	-	75	63.941	Eptatretus_burgeri
ENSG00000204590	GNL1	100	97.364	ENSEASG00005018610	GNL1	100	97.364	Equus_asinus_asinus
ENSG00000204590	GNL1	100	97.529	ENSECAG00000023081	GNL1	100	97.529	Equus_caballus
ENSG00000204590	GNL1	90	60.284	ENSELUG00000006281	gnl1	93	59.898	Esox_lucius
ENSG00000204590	GNL1	100	98.023	ENSFCAG00000007676	GNL1	100	98.023	Felis_catus
ENSG00000204590	GNL1	87	91.856	ENSFDAG00000000584	GNL1	100	90.909	Fukomys_damarensis
ENSG00000204590	GNL1	90	60.036	ENSFHEG00000011353	gnl1	89	59.246	Fundulus_heteroclitus
ENSG00000204590	GNL1	90	58.602	ENSGMOG00000015224	gnl1	90	57.554	Gadus_morhua
ENSG00000204590	GNL1	90	59.820	ENSGAFG00000014611	gnl1	88	59.206	Gambusia_affinis
ENSG00000204590	GNL1	92	58.290	ENSGACG00000009765	gnl1	100	54.662	Gasterosteus_aculeatus
ENSG00000204590	GNL1	100	99.341	ENSGGOG00000014590	GNL1	100	99.341	Gorilla_gorilla
ENSG00000204590	GNL1	96	58.136	ENSHBUG00000016745	gnl1	88	59.601	Haplochromis_burtoni
ENSG00000204590	GNL1	100	90.180	ENSHGLG00000017193	GNL1	100	89.525	Heterocephalus_glaber_female
ENSG00000204590	GNL1	87	88.636	ENSHGLG00100009994	GNL1	100	89.583	Heterocephalus_glaber_male
ENSG00000204590	GNL1	93	59.130	ENSHCOG00000012493	gnl1	89	59.820	Hippocampus_comes
ENSG00000204590	GNL1	90	58.770	ENSIPUG00000004850	gnl1	99	56.472	Ictalurus_punctatus
ENSG00000204590	GNL1	100	96.870	ENSSTOG00000011822	GNL1	100	96.870	Ictidomys_tridecemlineatus
ENSG00000204590	GNL1	100	94.408	ENSJJAG00000010831	-	100	93.586	Jaculus_jaculus
ENSG00000204590	GNL1	90	59.459	ENSKMAG00000009059	gnl1	89	58.739	Kryptolebias_marmoratus
ENSG00000204590	GNL1	90	58.813	ENSLBEG00000011038	gnl1	89	58.813	Labrus_bergylta
ENSG00000204590	GNL1	100	67.537	ENSLACG00000001713	GNL1	100	67.320	Latimeria_chalumnae
ENSG00000204590	GNL1	100	95.717	ENSLAFG00000030406	GNL1	100	95.717	Loxodonta_africana
ENSG00000204590	GNL1	100	99.176	ENSMFAG00000001167	GNL1	100	99.176	Macaca_fascicularis
ENSG00000204590	GNL1	100	99.176	ENSMMUG00000020077	GNL1	100	99.176	Macaca_mulatta
ENSG00000204590	GNL1	100	99.176	ENSMNEG00000031618	GNL1	100	99.176	Macaca_nemestrina
ENSG00000204590	GNL1	100	99.176	ENSMLEG00000030252	GNL1	100	99.176	Mandrillus_leucophaeus
ENSG00000204590	GNL1	96	57.673	ENSMAMG00000003554	gnl1	89	59.099	Mastacembelus_armatus
ENSG00000204590	GNL1	96	58.136	ENSMZEG00005018216	gnl1	88	59.601	Maylandia_zebra
ENSG00000204590	GNL1	100	92.282	ENSMAUG00000015596	Gnl1	100	91.461	Mesocricetus_auratus
ENSG00000204590	GNL1	100	98.188	ENSMICG00000014708	GNL1	100	98.188	Microcebus_murinus
ENSG00000204590	GNL1	100	96.211	ENSMOCG00000020934	Gnl1	100	96.211	Microtus_ochrogaster
ENSG00000204590	GNL1	96	57.022	ENSMMOG00000015833	gnl1	89	58.228	Mola_mola
ENSG00000204590	GNL1	100	83.690	ENSMODG00000015964	GNL1	95	83.690	Monodelphis_domestica
ENSG00000204590	GNL1	92	58.464	ENSMALG00000022523	gnl1	89	58.919	Monopterus_albus
ENSG00000204590	GNL1	100	93.245	MGP_CAROLIEiJ_G0021547	Gnl1	100	94.563	Mus_caroli
ENSG00000204590	GNL1	100	95.387	ENSMUSG00000024429	Gnl1	100	95.387	Mus_musculus
ENSG00000204590	GNL1	100	95.552	MGP_PahariEiJ_G0020539	Gnl1	100	95.552	Mus_pahari
ENSG00000204590	GNL1	100	95.058	MGP_SPRETEiJ_G0022452	Gnl1	100	95.058	Mus_spretus
ENSG00000204590	GNL1	99	96.578	ENSMPUG00000011828	GNL1	79	97.770	Mustela_putorius_furo
ENSG00000204590	GNL1	96	93.003	ENSMLUG00000008722	GNL1	97	91.297	Myotis_lucifugus
ENSG00000204590	GNL1	100	95.387	ENSNGAG00000000745	Gnl1	100	95.387	Nannospalax_galili
ENSG00000204590	GNL1	96	57.966	ENSNBRG00000020813	gnl1	89	59.420	Neolamprologus_brichardi
ENSG00000204590	GNL1	92	99.174	ENSNLEG00000005058	GNL1	83	95.486	Nomascus_leucogenys
ENSG00000204590	GNL1	87	94.497	ENSOPRG00000000007	GNL1	100	94.497	Ochotona_princeps
ENSG00000204590	GNL1	100	90.805	ENSODEG00000018111	GNL1	100	90.969	Octodon_degus
ENSG00000204590	GNL1	96	58.136	ENSONIG00000013044	gnl1	88	59.601	Oreochromis_niloticus
ENSG00000204590	GNL1	100	96.376	ENSOCUG00000002110	GNL1	100	96.376	Oryctolagus_cuniculus
ENSG00000204590	GNL1	90	58.813	ENSORLG00000012862	gnl1	89	58.018	Oryzias_latipes
ENSG00000204590	GNL1	90	58.887	ENSORLG00020003923	gnl1	89	58.273	Oryzias_latipes_hni
ENSG00000204590	GNL1	90	58.813	ENSORLG00015009552	gnl1	89	58.018	Oryzias_latipes_hsok
ENSG00000204590	GNL1	96	56.926	ENSOMEG00000014409	gnl1	89	58.018	Oryzias_melastigma
ENSG00000204590	GNL1	100	97.858	ENSOGAG00000004428	-	100	97.858	Otolemur_garnettii
ENSG00000204590	GNL1	98	91.779	ENSOGAG00000024106	-	100	90.772	Otolemur_garnettii
ENSG00000204590	GNL1	100	95.285	ENSOARG00000012966	GNL1	100	95.285	Ovis_aries
ENSG00000204590	GNL1	100	99.506	ENSPPAG00000044009	GNL1	100	99.506	Pan_paniscus
ENSG00000204590	GNL1	100	97.694	ENSPPRG00000007039	GNL1	100	97.694	Panthera_pardus
ENSG00000204590	GNL1	100	97.529	ENSPTIG00000011307	GNL1	100	97.529	Panthera_tigris_altaica
ENSG00000204590	GNL1	99	99.338	ENSPTRG00000017928	GNL1	99	99.338	Pan_troglodytes
ENSG00000204590	GNL1	100	99.176	ENSPANG00000020097	GNL1	100	99.176	Papio_anubis
ENSG00000204590	GNL1	90	60.036	ENSPKIG00000002200	gnl1	99	57.050	Paramormyrops_kingsleyae
ENSG00000204590	GNL1	94	56.997	ENSPSIG00000008441	GNL1	98	56.870	Pelodiscus_sinensis
ENSG00000204590	GNL1	90	58.559	ENSPMGG00000007259	gnl1	99	56.452	Periophthalmus_magnuspinnatus
ENSG00000204590	GNL1	97	94.558	ENSPEMG00000002731	Gnl1	99	95.197	Peromyscus_maniculatus_bairdii
ENSG00000204590	GNL1	100	85.338	ENSPCIG00000014975	GNL1	100	85.338	Phascolarctos_cinereus
ENSG00000204590	GNL1	90	60.360	ENSPFOG00000015398	gnl1	89	59.747	Poecilia_formosa
ENSG00000204590	GNL1	90	60.180	ENSPLAG00000003231	gnl1	88	59.567	Poecilia_latipinna
ENSG00000204590	GNL1	90	60.721	ENSPMEG00000005001	gnl1	89	60.108	Poecilia_mexicana
ENSG00000204590	GNL1	90	60.721	ENSPREG00000012818	gnl1	89	60.108	Poecilia_reticulata
ENSG00000204590	GNL1	100	99.341	ENSPPYG00000016408	GNL1	100	99.341	Pongo_abelii
ENSG00000204590	GNL1	67	96.023	ENSPCAG00000004522	-	70	96.500	Procavia_capensis
ENSG00000204590	GNL1	100	98.353	ENSPCOG00000015669	GNL1	100	98.353	Propithecus_coquereli
ENSG00000204590	GNL1	100	95.895	ENSPVAG00000003970	GNL1	100	95.895	Pteropus_vampyrus
ENSG00000204590	GNL1	96	57.966	ENSPNYG00000022614	gnl1	88	59.420	Pundamilia_nyererei
ENSG00000204590	GNL1	90	60.073	ENSPNAG00000021257	gnl1	99	57.398	Pygocentrus_nattereri
ENSG00000204590	GNL1	100	95.717	ENSRNOG00000000798	Gnl1	100	96.653	Rattus_norvegicus
ENSG00000204590	GNL1	100	99.176	ENSRBIG00000019143	GNL1	100	99.176	Rhinopithecus_bieti
ENSG00000204590	GNL1	100	99.176	ENSRROG00000030029	GNL1	100	99.176	Rhinopithecus_roxellana
ENSG00000204590	GNL1	100	99.176	ENSSBOG00000031909	GNL1	100	99.176	Saimiri_boliviensis_boliviensis
ENSG00000204590	GNL1	100	80.725	ENSSHAG00000007557	GNL1	100	80.560	Sarcophilus_harrisii
ENSG00000204590	GNL1	90	62.842	ENSSFOG00015013921	gnl1	99	59.451	Scleropages_formosus
ENSG00000204590	GNL1	90	57.885	ENSSMAG00000010147	gnl1	89	57.527	Scophthalmus_maximus
ENSG00000204590	GNL1	96	57.336	ENSSDUG00000013824	gnl1	88	59.173	Seriola_dumerili
ENSG00000204590	GNL1	96	57.576	ENSSLDG00000024560	gnl1	88	59.246	Seriola_lalandi_dorsalis
ENSG00000204590	GNL1	56	96.250	ENSSARG00000006156	-	84	96.250	Sorex_araneus
ENSG00000204590	GNL1	100	66.506	ENSSPUG00000015374	GNL1	100	66.506	Sphenodon_punctatus
ENSG00000204590	GNL1	90	59.892	ENSSPAG00000017541	gnl1	88	58.919	Stegastes_partitus
ENSG00000204590	GNL1	100	98.188	ENSSSCG00000001372	GNL1	100	98.188	Sus_scrofa
ENSG00000204590	GNL1	90	58.047	ENSTRUG00000011226	gnl1	85	56.884	Takifugu_rubripes
ENSG00000204590	GNL1	90	57.428	ENSTNIG00000008017	gnl1	91	57.428	Tetraodon_nigroviridis
ENSG00000204590	GNL1	100	90.280	ENSTBEG00000007538	GNL1	100	90.280	Tupaia_belangeri
ENSG00000204590	GNL1	100	96.540	ENSTTRG00000008287	GNL1	100	96.540	Tursiops_truncatus
ENSG00000204590	GNL1	100	97.694	ENSUAMG00000007671	GNL1	100	97.694	Ursus_americanus
ENSG00000204590	GNL1	100	92.471	ENSUMAG00000018935	GNL1	100	97.049	Ursus_maritimus
ENSG00000204590	GNL1	100	97.694	ENSVVUG00000009537	GNL1	100	97.694	Vulpes_vulpes
ENSG00000204590	GNL1	100	63.065	ENSXETG00000024087	gnl1	100	63.857	Xenopus_tropicalis
ENSG00000204590	GNL1	92	60.247	ENSXCOG00000019185	gnl1	88	60.145	Xiphophorus_couchianus
ENSG00000204590	GNL1	92	60.247	ENSXMAG00000011015	gnl1	88	60.145	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0002456	T cell mediated immunity	8180467.	NAS	Process
GO:0005198	structural molecule activity	8180467.	NAS	Function
GO:0005525	GTP binding	8180467.	NAS	Function
GO:0005615	extracellular space	8180467.	NAS	Component
GO:0005634	nucleus	21630459.	HDA	Component
GO:0006974	cellular response to DNA damage stimulus	17525332.	IDA	Process
GO:0007165	signal transduction	8180467.	NAS	Process