EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000204822 (Gene tree)
Gene ID: 116540
Gene Symbol: MRPL53
Alias: N
Full Name: mitochondrial ribosomal protein L53
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 1,365 bases
Position: chr2:74,471,958-74,473,322
Accession: 16684
RBP type: canonical RBP
Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 1p. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000258105	MRP_L53	PF10780.9	3.6e-15	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000409710	MRPL53-202	386	-	ENSP00000386920	70 (aa)	-	B9A051
ENST00000258105	MRPL53-201	1162	-	ENSP00000258105	112 (aa)	-	Q96EL3
ENST00000468875	MRPL53-204	574	-	-	- (aa)	-	-
ENST00000467349	MRPL53-203	451	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000204822's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000204822's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000204822	MRPL53	100	91.071	ENSAMEG00000017229	MRPL53	100	91.071	Ailuropoda_melanoleuca
ENSG00000204822	MRPL53	100	91.964	ENSANAG00000032295	MRPL53	100	91.964	Aotus_nancymaae
ENSG00000204822	MRPL53	100	91.964	ENSBTAG00000016599	MRPL53	100	91.964	Bos_taurus
ENSG00000204822	MRPL53	100	92.857	ENSCJAG00000043158	MRPL53	100	92.857	Callithrix_jacchus
ENSG00000204822	MRPL53	100	91.964	ENSCAFG00020014067	MRPL53	100	91.964	Canis_lupus_dingo
ENSG00000204822	MRPL53	100	69.565	ENSCHIG00000020713	-	100	69.565	Capra_hircus
ENSG00000204822	MRPL53	100	91.071	ENSCHIG00000009415	-	100	91.071	Capra_hircus
ENSG00000204822	MRPL53	96	87.037	ENSCHIG00000021224	-	84	87.037	Capra_hircus
ENSG00000204822	MRPL53	93	80.769	ENSTSYG00000037574	-	80	80.769	Carlito_syrichta
ENSG00000204822	MRPL53	100	92.857	ENSTSYG00000002278	-	100	92.857	Carlito_syrichta
ENSG00000204822	MRPL53	100	83.929	ENSCPOG00000035123	MRPL53	100	83.929	Cavia_porcellus
ENSG00000204822	MRPL53	100	92.857	ENSCCAG00000025749	MRPL53	100	92.857	Cebus_capucinus
ENSG00000204822	MRPL53	100	94.643	ENSCATG00000009492	MRPL53	100	94.643	Cercocebus_atys
ENSG00000204822	MRPL53	100	87.500	ENSCLAG00000005239	MRPL53	100	87.500	Chinchilla_lanigera
ENSG00000204822	MRPL53	100	95.536	ENSCSAG00000015617	MRPL53	100	95.536	Chlorocebus_sabaeus
ENSG00000204822	MRPL53	100	97.321	ENSCANG00000042942	MRPL53	100	97.321	Colobus_angolensis_palliatus
ENSG00000204822	MRPL53	99	76.724	ENSCGRG00001012557	Mrpl53	97	78.448	Cricetulus_griseus_chok1gshd
ENSG00000204822	MRPL53	99	76.724	ENSCGRG00000008972	Mrpl53	97	78.448	Cricetulus_griseus_crigri
ENSG00000204822	MRPL53	100	81.250	ENSDNOG00000046731	MRPL53	100	81.250	Dasypus_novemcinctus
ENSG00000204822	MRPL53	87	91.753	ENSETEG00000012580	MRPL53	99	87.500	Echinops_telfairi
ENSG00000204822	MRPL53	99	86.207	ENSEASG00005010610	MRPL53	99	87.069	Equus_asinus_asinus
ENSG00000204822	MRPL53	99	86.207	ENSECAG00000026983	MRPL53	99	87.069	Equus_caballus
ENSG00000204822	MRPL53	100	91.071	ENSFCAG00000036033	MRPL53	100	91.071	Felis_catus
ENSG00000204822	MRPL53	100	82.143	ENSFDAG00000010624	MRPL53	100	82.143	Fukomys_damarensis
ENSG00000204822	MRPL53	100	99.107	ENSGGOG00000006504	MRPL53	100	99.107	Gorilla_gorilla
ENSG00000204822	MRPL53	99	81.982	ENSHGLG00000009928	MRPL53	99	81.982	Heterocephalus_glaber_female
ENSG00000204822	MRPL53	99	81.982	ENSHGLG00100017366	MRPL53	99	81.982	Heterocephalus_glaber_male
ENSG00000204822	MRPL53	100	87.500	ENSSTOG00000001025	MRPL53	100	87.500	Ictidomys_tridecemlineatus
ENSG00000204822	MRPL53	99	84.685	ENSJJAG00000011605	Mrpl53	99	84.685	Jaculus_jaculus
ENSG00000204822	MRPL53	88	83.838	ENSLAFG00000007990	MRPL53	100	83.838	Loxodonta_africana
ENSG00000204822	MRPL53	100	94.643	ENSMFAG00000002637	MRPL53	100	94.643	Macaca_fascicularis
ENSG00000204822	MRPL53	100	94.643	ENSMNEG00000040378	MRPL53	100	94.643	Macaca_nemestrina
ENSG00000204822	MRPL53	100	93.750	ENSMLEG00000032167	MRPL53	100	93.750	Mandrillus_leucophaeus
ENSG00000204822	MRPL53	99	84.483	ENSMAUG00000010618	Mrpl53	97	85.586	Mesocricetus_auratus
ENSG00000204822	MRPL53	100	91.964	ENSMICG00000042776	MRPL53	100	91.964	Microcebus_murinus
ENSG00000204822	MRPL53	99	86.486	ENSMOCG00000015167	Mrpl53	97	86.486	Microtus_ochrogaster
ENSG00000204822	MRPL53	100	81.356	MGP_CAROLIEiJ_G0028544	Mrpl53	92	87.156	Mus_caroli
ENSG00000204822	MRPL53	88	90.816	ENSMUSG00000030037	Mrpl53	92	87.156	Mus_musculus
ENSG00000204822	MRPL53	88	89.796	MGP_PahariEiJ_G0022279	Mrpl53	92	86.239	Mus_pahari
ENSG00000204822	MRPL53	88	90.816	MGP_SPRETEiJ_G0029550	Mrpl53	92	87.156	Mus_spretus
ENSG00000204822	MRPL53	100	91.071	ENSMPUG00000008055	MRPL53	100	91.071	Mustela_putorius_furo
ENSG00000204822	MRPL53	99	84.685	ENSMLUG00000002655	MRPL53	100	84.685	Myotis_lucifugus
ENSG00000204822	MRPL53	100	81.897	ENSNGAG00000001052	Mrpl53	100	82.759	Nannospalax_galili
ENSG00000204822	MRPL53	100	97.321	ENSNLEG00000032770	MRPL53	100	97.321	Nomascus_leucogenys
ENSG00000204822	MRPL53	94	69.811	ENSMEUG00000008909	MRPL53	100	69.811	Notamacropus_eugenii
ENSG00000204822	MRPL53	100	88.496	ENSOCUG00000015342	MRPL53	100	88.496	Oryctolagus_cuniculus
ENSG00000204822	MRPL53	100	93.750	ENSOGAG00000001059	MRPL53	100	93.750	Otolemur_garnettii
ENSG00000204822	MRPL53	100	91.964	ENSOARG00000012700	MRPL53	100	91.964	Ovis_aries
ENSG00000204822	MRPL53	100	99.107	ENSPPAG00000029905	MRPL53	100	99.107	Pan_paniscus
ENSG00000204822	MRPL53	100	91.071	ENSPPRG00000008059	MRPL53	100	91.071	Panthera_pardus
ENSG00000204822	MRPL53	100	91.071	ENSPTIG00000011649	MRPL53	100	91.071	Panthera_tigris_altaica
ENSG00000204822	MRPL53	100	99.107	ENSPTRG00000044829	MRPL53	100	99.107	Pan_troglodytes
ENSG00000204822	MRPL53	100	94.643	ENSPANG00000032404	MRPL53	100	94.643	Papio_anubis
ENSG00000204822	MRPL53	99	83.784	ENSPEMG00000008725	Mrpl53	97	83.784	Peromyscus_maniculatus_bairdii
ENSG00000204822	MRPL53	96	84.259	ENSPCAG00000016829	MRPL53	96	84.259	Procavia_capensis
ENSG00000204822	MRPL53	100	91.071	ENSPCOG00000028676	MRPL53	100	91.071	Propithecus_coquereli
ENSG00000204822	MRPL53	100	90.179	ENSPVAG00000013958	MRPL53	100	90.179	Pteropus_vampyrus
ENSG00000204822	MRPL53	84	91.489	ENSRNOG00000053109	Mrpl53	92	86.239	Rattus_norvegicus
ENSG00000204822	MRPL53	84	91.489	ENSRNOG00000052279	LOC103692169	92	86.239	Rattus_norvegicus
ENSG00000204822	MRPL53	100	95.536	ENSRBIG00000013215	MRPL53	100	95.536	Rhinopithecus_bieti
ENSG00000204822	MRPL53	99	95.495	ENSRROG00000045669	MRPL53	99	95.495	Rhinopithecus_roxellana
ENSG00000204822	MRPL53	100	91.964	ENSSBOG00000026949	MRPL53	100	91.964	Saimiri_boliviensis_boliviensis
ENSG00000204822	MRPL53	94	68.868	ENSSHAG00000016957	MRPL53	99	68.868	Sarcophilus_harrisii
ENSG00000204822	MRPL53	100	84.071	ENSSARG00000010686	MRPL53	100	84.071	Sorex_araneus
ENSG00000204822	MRPL53	88	92.929	ENSTBEG00000017688	MRPL53	97	92.929	Tupaia_belangeri
ENSG00000204822	MRPL53	100	93.750	ENSTTRG00000012719	MRPL53	100	93.750	Tursiops_truncatus
ENSG00000204822	MRPL53	100	90.179	ENSUAMG00000021706	MRPL53	100	90.179	Ursus_americanus
ENSG00000204822	MRPL53	100	90.179	ENSUMAG00000001594	MRPL53	100	90.179	Ursus_maritimus
ENSG00000204822	MRPL53	100	91.071	ENSVVUG00000004459	MRPL53	100	91.071	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	25416956.	IPI	Function
GO:0005739	mitochondrion	28892042.	IDA	Component
GO:0005743	mitochondrial inner membrane	-	TAS	Component
GO:0005762	mitochondrial large ribosomal subunit	25278503.28892042.	IDA	Component
GO:0070125	mitochondrial translational elongation	-	TAS	Process
GO:0070126	mitochondrial translational termination	-	TAS	Process