EuRBPDB

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  • Description
  • RBPome
  • Expression
  • Transcripts
  • Gene Model
  • Phenotypes
  • GWAS
  • PPI
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000205531 (Gene tree)
Gene ID
4676
Gene Symbol
NAP1L4
Alias
NAP2
Full Name
nucleosome assembly protein 1 like 4
Gene Type
protein_coding
Species
Homo_sapiens
Status
putative
Strand
Minus strand
Length
47,948 bases
Position
chr11:2,944,430-2,992,377
Accession
7640
RBP type
non-canonical RBP
Summary
This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. [provided by RefSeq, Jul 2008]
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
22658674Insights into RNA biology from an atlas of mammalian mRNA-binding proteinsRIC & Hela2012 May 31Castello ADOI: 10.1016/j.cell.2012.04.031
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & MCF10A2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & MCF72018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000399614NAP1L4-202594-ENSP00000382523156 (aa)-A8MXH2
ENST00000526842NAP1L4-213535-ENSP00000431799128 (aa)-E9PJJ2
ENST00000526023NAP1L4-211477--- (aa)--
ENST00000620138NAP1L4-2222479-ENSP00000481412386 (aa)-Q99733
ENST00000483643NAP1L4-208690--- (aa)--
ENST00000430811NAP1L4-203860-ENSP00000405912178 (aa)-C9J6D1
ENST00000528363NAP1L4-215685--- (aa)--
ENST00000532325NAP1L4-220526-ENSP00000436488154 (aa)-E9PP22
ENST00000531291NAP1L4-219572-ENSP00000437130107 (aa)-E9PNW0
ENST00000469089NAP1L4-206707--- (aa)--
ENST00000530064NAP1L4-218625-ENSP00000432126133 (aa)-E9PS34
ENST00000528968NAP1L4-216587-ENSP00000434759140 (aa)-E9PNJ7
ENST00000492594NAP1L4-209570--- (aa)--
ENST00000448187NAP1L4-204888-ENSP00000387783278 (aa)-C9JZI7
ENST00000526115NAP1L4-2121941-ENSP00000436397386 (aa)-Q99733
ENST00000534372NAP1L4-221544-ENSP0000043351278 (aa)-E9PKI2
ENST00000380542NAP1L4-2012511-ENSP00000369915375 (aa)-Q99733
ENST00000455338NAP1L4-205352-ENSP00000412048101 (aa)-C9J1B1
ENST00000529361NAP1L4-217555-ENSP00000435327169 (aa)-E9PKT8
ENST00000528261NAP1L4-214644--- (aa)--
ENST00000492685NAP1L4-210850-ENSP00000431644204 (aa)-H0YCI4
ENST00000469805NAP1L4-2072294--- (aa)--
Gene Model
Click here to download ENSG00000205531's gene model file
Phenotypes
ensgIDTraitpValuePubmed ID
ENSG00000205531Alcoholism7.45E-05-
ENSG00000205531Hemoglobins7.321e-005-
ENSG00000205531Erythrocyte Indices3.172e-006-
ENSG00000205531Erythrocyte Indices2.069e-005-
ENSG00000205531Electrocardiography1.104e-006-
GWAS
ensgIDSNPChromosomePositionSNP-risk TraitPubmedID95% CIOr or BEAT EFO ID
ENSG00000205531rs7948848112960666?White blood cell count30595370EFO_0004308
ENSG00000205531rs7109587112967009?Eosinophil counts30595370EFO_0004842
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000205531's network

* RBP PPI network refers to all genes directly bind to RBP
Orthologs identified by RBPome
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000205531NAP1L48976.923ENSG00000187109NAP1L110073.239Homo_sapiens
ENSG00000205531NAP1L49997.015ENSMUSG00000059119Nap1l410094.819Mus_musculus
ENSG00000205531NAP1L48977.473ENSMUSG00000058799Nap1l19168.421Mus_musculus
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0003723RNA binding22658674.HDAFunction
GO:0005515protein binding22190034.IPIFunction
GO:0005634nucleus9325046.IDAComponent
GO:0005737cytoplasm9325046.IDAComponent
GO:0006334nucleosome assembly9325046.IDAProcess
GO:0031491nucleosome binding9325046.IDAFunction
GO:0051082unfolded protein binding9325046.TASFunction

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