EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000205937 (Gene tree)
Gene ID: 10921
Gene Symbol: RNPS1
Alias: N
Full Name: RNA binding protein with serine rich domain 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 15,297 bases
Position: chr16:2,253,116-2,268,412
Accession: 10080
RBP type: canonical RBP
Summary: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000457987	RRM_1	PF00076.22	1.3e-17	1	1
ENSP00000454461	RRM_1	PF00076.22	2.2e-17	1	1
ENSP00000456352	RRM_1	PF00076.22	2.2e-17	1	1
ENSP00000457110	RRM_1	PF00076.22	2.4e-17	1	1
ENSP00000301730	RRM_1	PF00076.22	2.4e-17	1	1
ENSP00000315859	RRM_1	PF00076.22	2.4e-17	1	1
ENSP00000380275	RRM_1	PF00076.22	2.4e-17	1	1
ENSP00000457723	RRM_1	PF00076.22	2.4e-17	1	1
ENSP00000457820	RRM_1	PF00076.22	2.4e-17	1	1
ENSP00000454513	RRM_1	PF00076.22	4.3e-15	1	1
ENSP00000455306	RRM_1	PF00076.22	2.4e-13	1	1
ENSP00000455379	RRM_1	PF00076.22	2.4e-13	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
11477570	Binding of a SART3 tumor-rejection antigen to a pre-mRNA splicing factor RNPS1: a possible regulation of splicing by a complex formation.	Int J Cancer	2001 Sep 1	Harada K	-
10094314	The splicing factors 9G8 and SRp20 transactivate splicing through different and specific enhancers.	RNA	1999 Mar	Cavaloc Y	-
26965252	Characterization of RNA-Protein Interactions: Lessons from Two RNA-Binding Proteins, SRSF1 and SRSF2.	Methods Mol Biol	2016	Skrdlant L	doi: 10.1007/978-1-4939-3591-8_1.
27475226	Exon Junction Complexes Show a Distributional Bias toward Alternatively Spliced mRNAs and against mRNAs Coding for Ribosomal Proteins.	Cell Rep	2016 Aug 9	Hauer C	doi: 10.1016/j.celrep.2016.06.096
10022843	The splicing factor-associated protein, p32, regulates RNA splicing by inhibiting ASF/SF2 RNA binding and phosphorylation.	EMBO J	1999 Feb 15	Petersen-Mahrt SK	-
9580558	The RNP protein, RNPS1, associates with specific isoforms of the p34cdc2-related PITSLRE protein kinase in vivo.	J Cell Sci	1998 Jun	Loyer P	-
10477180	Characterization of a SR protein from Trypanosoma brucei with homology to RNA-binding cis-splicing proteins.	Mol Biochem Parasitol	1999 Jul 30	Ismaili N	-
9037021	Sequence-specific RNA binding by an SR protein requires RS domain phosphorylation: creation of an SRp40-specific splicing enhancer.	Proc Natl Acad Sci U S A	1997 Feb 18	Tacke R	-
12615334	An early ancestor in the evolution of splicing: a Trypanosoma cruzi serine-arginine-rich protein (TcSR) is functional in cis-splicing.	Mol Biochem Parasitol	2003 Mar	Portal D	-
16116479	Profiling estrogen-regulated gene expression changes in normal and malignant human ovarian surface epithelial cells.	Oncogene	2005 Dec 8	Syed V	-
14602908	Arginine/serine repeats are sufficient to constitute a splicing activation domain.	Nucleic Acids Res	2003 Nov 15	Philipps D	-
17959926	The RNA binding protein RNPS1 alleviates ASF/SF2 depletion-induced genomic instability.	RNA	2007 Dec	Li X	-
17183366	A nucleo-cytoplasmic SR protein functions in viral IRES-mediated translation initiation.	EMBO J	2007 Jan 24	Bedard KM	-
22388736	The structure of the ASAP core complex reveals the existence of a Pinin-containing PSAP complex.	Nat Struct Mol Biol	2012 Mar 4	Murachelli AG	doi: 10.1038/nsmb.2242.
23299886	Splicing factor SRSF3 is crucial for hepatocyte differentiation and metabolic function.	Nat Commun	2013	Sen S	doi: 10.1038/ncomms2342.
20857263	Novel cis-active structures in the coding region mediate CRM1-dependent nuclear export of IFN-α 1 mRNA.	Med Mol Morphol	2010 Sep	Kimura T	doi: 10.1007/s00795-010-0492-5
26603559	Transcriptome-Wide Identification of RNA Targets of Arabidopsis SERINE/ARGININE-RICH45 Uncovers the Unexpected Roles of This RNA Binding Protein in RNA Processing.	Plant Cell	2015 Dec	Xing D	doi: 10.1105/tpc.15.00641
27091468	Directional Phosphorylation and Nuclear Transport of the Splicing Factor SRSF1 Is Regulated by an RNA Recognition Motif.	J Mol Biol	2016 Jun 5	Serrano P	doi: 10.1016/j.jmb.2016.04.009
29750417	HITS-CLIP reveals sex-differential RNA binding and alterative splicing regulation of SRm160 in Drosophila.	J Mol Cell Biol	2019 Feb 1	Qiu C	doi: 10.1093/jmcb/mjy029.
30388412	Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons.	Mol Cell	2018 Nov 1	Gonatopoulos-Pournatzis T	doi: 10.1016/j.molcel.2018.10.008.
20826166	Mechanism of dephosphorylation of the SR protein ASF/SF2 by protein phosphatase 1.	J Mol Biol	2010 Oct 29	Ma CT	doi: 10.1016/j.jmb.2010.08.024
23160747	genes of Phanerochaete chrysosporium exposed to lead.	Bull Environ Contam Toxicol	2013 Jan	Tekin E	doi: 10.1007/s00128-012-0886-2
14729981	RNA folding affects the recruitment of SR proteins by mouse and human polypurinic enhancer elements in the fibronectin EDA exon.	Mol Cell Biol	2004 Feb	Buratti E	-
27596537	Evidence that a threshold of serine/arginine-rich (SR) proteins recruits CFIm to promote rous sarcoma virus mRNA 3' end formation.	Virology	2016 Nov	Hudson SW	doi: 10.1016/j.virol.2016.08.021
26385834	Human immunodeficiency virus type 1 splicing at the major splice donor site is controlled by highly conserved RNA sequence and structural elements.	J Gen Virol	2015 Nov	Mueller N	-
25779589	HIV-1 splicing is controlled by local RNA structure and binding of splicing regulatory proteins at the major 5' splice site.	J Gen Virol	2015 Jul	Mueller N	doi: 10.1099/vir.0.000122
30185622	Molecular interactions connecting the function of the serine-arginine-rich protein SRSF1 to protein phosphatase 1.	J Biol Chem	2018 Oct 26	Aubol BE	doi: 10.1074/jbc.RA118.004587

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000301730	RNPS1-201	1276	-	ENSP00000301730	305 (aa)	-	Q15287
ENST00000561718	RNPS1-205	1806	-	ENSP00000455306	128 (aa)	-	H3BPG5
ENST00000566783	RNPS1-221	1826	-	-	- (aa)	-	-
ENST00000397086	RNPS1-203	2069	XM_005255048	ENSP00000380275	305 (aa)	XP_005255105	Q15287
ENST00000567147	RNPS1-222	830	-	ENSP00000454513	257 (aa)	-	H3BMS0
ENST00000562205	RNPS1-206	2223	-	-	- (aa)	-	-
ENST00000563857	RNPS1-208	739	-	-	- (aa)	-	-
ENST00000565333	RNPS1-214	479	-	ENSP00000454867	85 (aa)	-	H3BNI3
ENST00000565870	RNPS1-217	1514	-	ENSP00000457110	302 (aa)	-	H3BTC0
ENST00000564311	RNPS1-209	870	-	ENSP00000455013	156 (aa)	-	H3BNU7
ENST00000562690	RNPS1-207	582	-	ENSP00000457296	127 (aa)	-	H3BTR6
ENST00000569598	RNPS1-224	918	-	ENSP00000457987	211 (aa)	-	H3BV80
ENST00000320225	RNPS1-202	2241	-	ENSP00000315859	305 (aa)	-	Q15287
ENST00000564822	RNPS1-212	314	-	ENSP00000456283	29 (aa)	-	H3BRK4
ENST00000565678	RNPS1-216	2298	-	ENSP00000457723	305 (aa)	-	Q15287
ENST00000565589	RNPS1-215	666	-	ENSP00000457338	45 (aa)	-	H3BTV0
ENST00000566458	RNPS1-220	2037	-	ENSP00000456352	282 (aa)	-	Q15287
ENST00000564601	RNPS1-210	903	-	ENSP00000457690	169 (aa)	-	H3BUL0
ENST00000566397	RNPS1-219	1685	-	ENSP00000455379	128 (aa)	-	H3BPG5
ENST00000570051	RNPS1-226	735	-	-	- (aa)	-	-
ENST00000564764	RNPS1-211	639	-	ENSP00000457378	150 (aa)	-	H3BTY0
ENST00000569709	RNPS1-225	574	-	ENSP00000455195	98 (aa)	-	H3BP82
ENST00000565243	RNPS1-213	3337	-	-	- (aa)	-	-
ENST00000566180	RNPS1-218	814	-	ENSP00000457618	139 (aa)	-	H3BUG0
ENST00000568631	RNPS1-223	1792	-	ENSP00000457820	305 (aa)	-	Q15287
ENST00000561518	RNPS1-204	1092	-	ENSP00000454461	284 (aa)	-	H3BMM9

Gene Model

Click here to download ENSG00000205937's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03013	RNA transport	KEGG
hsa03015	mRNA surveillance pathway	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000205937	Hemoglobin A, Glycosylated	5.8350000E-005	19875614

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000205937's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000205937	RNPS1	52	34.328	ENSG00000161547	SRSF2	55	31.507

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000205937	RNPS1	66	87.059	ENSAPOG00000014649	-	85	70.124	Acanthochromis_polyacanthus
ENSG00000205937	RNPS1	100	100.000	ENSAMEG00000017861	RNPS1	100	100.000	Ailuropoda_melanoleuca
ENSG00000205937	RNPS1	86	58.621	ENSACIG00000014367	-	76	66.512	Amphilophus_citrinellus
ENSG00000205937	RNPS1	85	70.417	ENSAOCG00000002404	RNPS1	84	70.417	Amphiprion_ocellaris
ENSG00000205937	RNPS1	66	87.059	ENSAPEG00000019263	-	81	69.136	Amphiprion_percula
ENSG00000205937	RNPS1	85	70.417	ENSAPEG00000006497	RNPS1	81	70.293	Amphiprion_percula
ENSG00000205937	RNPS1	56	63.265	ENSATEG00000000835	RNPS1	60	58.108	Anabas_testudineus
ENSG00000205937	RNPS1	85	72.083	ENSATEG00000024267	RNPS1	84	72.614	Anabas_testudineus
ENSG00000205937	RNPS1	100	77.778	ENSAPLG00000006231	RNPS1	65	93.548	Anas_platyrhynchos
ENSG00000205937	RNPS1	100	94.675	ENSACAG00000004088	RNPS1	94	90.987	Anolis_carolinensis
ENSG00000205937	RNPS1	91	97.403	ENSANAG00000029802	-	90	92.887	Aotus_nancymaae
ENSG00000205937	RNPS1	100	100.000	ENSANAG00000028802	RNPS1	100	100.000	Aotus_nancymaae
ENSG00000205937	RNPS1	92	61.217	ENSACLG00000021537	-	96	68.302	Astatotilapia_calliptera
ENSG00000205937	RNPS1	85	75.417	ENSAMXG00000006330	-	84	68.750	Astyanax_mexicanus
ENSG00000205937	RNPS1	66	78.824	ENSAMXG00000037447	RNPS1	75	68.980	Astyanax_mexicanus
ENSG00000205937	RNPS1	66	70.588	ENSBTAG00000052161	-	64	70.588	Bos_taurus
ENSG00000205937	RNPS1	100	100.000	ENSBTAG00000009969	RNPS1	100	99.344	Bos_taurus
ENSG00000205937	RNPS1	100	100.000	ENSCJAG00000014969	RNPS1	100	100.000	Callithrix_jacchus
ENSG00000205937	RNPS1	100	100.000	ENSCAFG00000019397	RNPS1	100	100.000	Canis_familiaris
ENSG00000205937	RNPS1	100	100.000	ENSCAFG00020026159	RNPS1	100	100.000	Canis_lupus_dingo
ENSG00000205937	RNPS1	86	100.000	ENSCHIG00000014621	-	73	97.196	Capra_hircus
ENSG00000205937	RNPS1	100	100.000	ENSTSYG00000001629	RNPS1	100	100.000	Carlito_syrichta
ENSG00000205937	RNPS1	100	97.041	ENSTSYG00000031848	-	98	95.417	Carlito_syrichta
ENSG00000205937	RNPS1	100	100.000	ENSCAPG00000007731	RNPS1	100	99.672	Cavia_aperea
ENSG00000205937	RNPS1	100	100.000	ENSCPOG00000002066	RNPS1	100	99.672	Cavia_porcellus
ENSG00000205937	RNPS1	100	100.000	ENSCCAG00000034480	RNPS1	100	99.672	Cebus_capucinus
ENSG00000205937	RNPS1	100	100.000	ENSCATG00000013756	RNPS1	100	100.000	Cercocebus_atys
ENSG00000205937	RNPS1	99	92.857	ENSCATG00000042361	-	100	88.031	Cercocebus_atys
ENSG00000205937	RNPS1	100	100.000	ENSCLAG00000015546	RNPS1	100	99.672	Chinchilla_lanigera
ENSG00000205937	RNPS1	100	97.163	ENSCSAG00000005219	-	95	97.163	Chlorocebus_sabaeus
ENSG00000205937	RNPS1	100	100.000	ENSCHOG00000004866	RNPS1	100	98.361	Choloepus_hoffmanni
ENSG00000205937	RNPS1	100	86.207	ENSCPBG00000000214	RNPS1	95	69.849	Chrysemys_picta_bellii
ENSG00000205937	RNPS1	100	84.030	ENSCANG00000030189	-	99	71.863	Colobus_angolensis_palliatus
ENSG00000205937	RNPS1	100	100.000	ENSCANG00000041307	RNPS1	100	100.000	Colobus_angolensis_palliatus
ENSG00000205937	RNPS1	100	100.000	ENSCGRG00001020431	Rnps1	100	100.000	Cricetulus_griseus_chok1gshd
ENSG00000205937	RNPS1	88	80.531	ENSCGRG00001010012	-	51	88.679	Cricetulus_griseus_chok1gshd
ENSG00000205937	RNPS1	88	80.531	ENSCGRG00000018236	-	51	88.679	Cricetulus_griseus_crigri
ENSG00000205937	RNPS1	100	100.000	ENSCGRG00000014021	Rnps1	100	99.344	Cricetulus_griseus_crigri
ENSG00000205937	RNPS1	99	96.850	ENSCGRG00000010104	-	100	96.850	Cricetulus_griseus_crigri
ENSG00000205937	RNPS1	86	69.136	ENSCSEG00000015997	RNPS1	82	69.874	Cynoglossus_semilaevis
ENSG00000205937	RNPS1	91	68.702	ENSCSEG00000000402	RNPS1	85	68.702	Cynoglossus_semilaevis
ENSG00000205937	RNPS1	86	65.306	ENSCVAG00000010868	RNPS1	75	64.815	Cyprinodon_variegatus
ENSG00000205937	RNPS1	85	63.750	ENSDARG00000100188	RNPS1	84	69.710	Danio_rerio
ENSG00000205937	RNPS1	85	63.750	ENSDARG00000116743	rnps1	84	69.710	Danio_rerio
ENSG00000205937	RNPS1	100	100.000	ENSDNOG00000016081	RNPS1	100	100.000	Dasypus_novemcinctus
ENSG00000205937	RNPS1	86	69.863	ENSDNOG00000038751	-	100	72.139	Dasypus_novemcinctus
ENSG00000205937	RNPS1	100	100.000	ENSDORG00000001755	Rnps1	100	99.344	Dipodomys_ordii
ENSG00000205937	RNPS1	100	100.000	ENSEASG00005004862	RNPS1	100	100.000	Equus_asinus_asinus
ENSG00000205937	RNPS1	100	100.000	ENSECAG00000023288	RNPS1	83	98.268	Equus_caballus
ENSG00000205937	RNPS1	100	100.000	ENSEEUG00000005933	RNPS1	100	80.984	Erinaceus_europaeus
ENSG00000205937	RNPS1	100	100.000	ENSFCAG00000007690	RNPS1	100	100.000	Felis_catus
ENSG00000205937	RNPS1	86	95.890	ENSFALG00000004868	RNPS1	85	95.417	Ficedula_albicollis
ENSG00000205937	RNPS1	100	100.000	ENSFDAG00000003386	RNPS1	100	99.344	Fukomys_damarensis
ENSG00000205937	RNPS1	86	65.753	ENSFHEG00000011705	RNPS1	75	71.429	Fundulus_heteroclitus
ENSG00000205937	RNPS1	86	95.862	ENSGALG00000009288	RNPS1	85	95.417	Gallus_gallus
ENSG00000205937	RNPS1	85	68.465	ENSGACG00000005641	-	84	68.465	Gasterosteus_aculeatus
ENSG00000205937	RNPS1	100	92.667	ENSGAGG00000010452	RNPS1	86	93.156	Gopherus_agassizii
ENSG00000205937	RNPS1	100	96.935	ENSGGOG00000026421	-	100	96.935	Gorilla_gorilla
ENSG00000205937	RNPS1	100	100.000	ENSGGOG00000014275	RNPS1	100	100.000	Gorilla_gorilla
ENSG00000205937	RNPS1	66	84.706	ENSHBUG00000017337	-	84	72.199	Haplochromis_burtoni
ENSG00000205937	RNPS1	100	97.041	ENSHGLG00000006292	-	97	95.142	Heterocephalus_glaber_female
ENSG00000205937	RNPS1	100	100.000	ENSHGLG00000013957	RNPS1	100	100.000	Heterocephalus_glaber_female
ENSG00000205937	RNPS1	52	95.522	ENSHGLG00000003843	-	55	95.522	Heterocephalus_glaber_female
ENSG00000205937	RNPS1	100	100.000	ENSHGLG00100003539	RNPS1	100	100.000	Heterocephalus_glaber_male
ENSG00000205937	RNPS1	92	94.231	ENSHGLG00100015267	-	80	95.495	Heterocephalus_glaber_male
ENSG00000205937	RNPS1	100	91.111	ENSHGLG00100017879	-	80	70.248	Heterocephalus_glaber_male
ENSG00000205937	RNPS1	80	90.533	ENSHGLG00100010622	-	74	91.589	Heterocephalus_glaber_male
ENSG00000205937	RNPS1	100	100.000	ENSHGLG00100001721	-	65	88.614	Heterocephalus_glaber_male
ENSG00000205937	RNPS1	100	80.156	ENSHGLG00100011610	-	100	81.712	Heterocephalus_glaber_male
ENSG00000205937	RNPS1	86	78.231	ENSIPUG00000011746	rnps1	93	78.423	Ictalurus_punctatus
ENSG00000205937	RNPS1	100	100.000	ENSSTOG00000013200	RNPS1	100	88.197	Ictidomys_tridecemlineatus
ENSG00000205937	RNPS1	96	83.721	ENSJJAG00000019234	-	68	79.498	Jaculus_jaculus
ENSG00000205937	RNPS1	100	100.000	ENSJJAG00000015576	-	100	99.672	Jaculus_jaculus
ENSG00000205937	RNPS1	67	94.186	ENSJJAG00000000532	-	60	95.968	Jaculus_jaculus
ENSG00000205937	RNPS1	85	71.784	ENSKMAG00000009135	RNPS1	84	67.220	Kryptolebias_marmoratus
ENSG00000205937	RNPS1	66	77.647	ENSLBEG00000024091	RNPS1	75	64.651	Labrus_bergylta
ENSG00000205937	RNPS1	66	89.412	ENSLBEG00000015904	-	59	83.871	Labrus_bergylta
ENSG00000205937	RNPS1	85	87.917	ENSLACG00000007112	RNPS1	85	87.917	Latimeria_chalumnae
ENSG00000205937	RNPS1	86	78.621	ENSLOCG00000001758	RNPS1	84	83.333	Lepisosteus_oculatus
ENSG00000205937	RNPS1	100	100.000	ENSLAFG00000000728	RNPS1	50	100.000	Loxodonta_africana
ENSG00000205937	RNPS1	100	100.000	ENSMFAG00000042142	RNPS1	100	100.000	Macaca_fascicularis
ENSG00000205937	RNPS1	100	96.552	ENSMFAG00000044121	-	83	83.265	Macaca_fascicularis
ENSG00000205937	RNPS1	100	100.000	ENSMMUG00000019238	-	100	100.000	Macaca_mulatta
ENSG00000205937	RNPS1	100	96.552	ENSMMUG00000041726	-	92	94.677	Macaca_mulatta
ENSG00000205937	RNPS1	100	96.552	ENSMNEG00000024827	-	92	95.057	Macaca_nemestrina
ENSG00000205937	RNPS1	100	100.000	ENSMLEG00000036928	RNPS1	100	100.000	Mandrillus_leucophaeus
ENSG00000205937	RNPS1	100	91.051	ENSMLEG00000040232	-	100	91.051	Mandrillus_leucophaeus
ENSG00000205937	RNPS1	92	68.582	ENSMAMG00000021148	-	88	68.199	Mastacembelus_armatus
ENSG00000205937	RNPS1	93	64.898	ENSMAMG00000021609	-	84	70.539	Mastacembelus_armatus
ENSG00000205937	RNPS1	66	84.706	ENSMZEG00005006256	-	85	72.199	Maylandia_zebra
ENSG00000205937	RNPS1	99	93.919	ENSMGAG00000010042	RNPS1	98	94.492	Meleagris_gallopavo
ENSG00000205937	RNPS1	100	100.000	ENSMAUG00000004017	-	100	100.000	Mesocricetus_auratus
ENSG00000205937	RNPS1	100	100.000	ENSMICG00000031543	RNPS1	100	99.526	Microcebus_murinus
ENSG00000205937	RNPS1	100	100.000	ENSMOCG00000003429	Rnps1	100	100.000	Microtus_ochrogaster
ENSG00000205937	RNPS1	86	61.379	ENSMMOG00000010863	RNPS1	75	65.116	Mola_mola
ENSG00000205937	RNPS1	100	99.219	ENSMODG00000015891	RNPS1	100	97.712	Monodelphis_domestica
ENSG00000205937	RNPS1	100	100.000	MGP_CAROLIEiJ_G0021182	-	52	100.000	Mus_caroli
ENSG00000205937	RNPS1	100	100.000	ENSMUSG00000034681	Rnps1	100	100.000	Mus_musculus
ENSG00000205937	RNPS1	100	100.000	MGP_PahariEiJ_G0023498	Rnps1	100	100.000	Mus_pahari
ENSG00000205937	RNPS1	100	100.000	MGP_SPRETEiJ_G0022092	Rnps1	100	100.000	Mus_spretus
ENSG00000205937	RNPS1	100	100.000	ENSMLUG00000016808	RNPS1	100	100.000	Myotis_lucifugus
ENSG00000205937	RNPS1	100	100.000	ENSNGAG00000023702	Rnps1	100	100.000	Nannospalax_galili
ENSG00000205937	RNPS1	66	84.706	ENSNBRG00000014540	-	92	68.750	Neolamprologus_brichardi
ENSG00000205937	RNPS1	86	62.759	ENSNBRG00000023437	RNPS1	75	66.512	Neolamprologus_brichardi
ENSG00000205937	RNPS1	100	100.000	ENSNLEG00000009243	RNPS1	100	98.162	Nomascus_leucogenys
ENSG00000205937	RNPS1	100	97.887	ENSMEUG00000008882	RNPS1	100	96.721	Notamacropus_eugenii
ENSG00000205937	RNPS1	100	100.000	ENSOPRG00000016422	RNPS1	100	96.721	Ochotona_princeps
ENSG00000205937	RNPS1	99	73.228	ENSODEG00000003850	-	55	90.476	Octodon_degus
ENSG00000205937	RNPS1	93	67.005	ENSODEG00000002513	-	79	68.047	Octodon_degus
ENSG00000205937	RNPS1	66	94.737	ENSODEG00000017258	-	77	68.047	Octodon_degus
ENSG00000205937	RNPS1	66	84.706	ENSONIG00000019627	-	85	71.784	Oreochromis_niloticus
ENSG00000205937	RNPS1	92	65.019	ENSORLG00015011183	RNPS1	74	71.369	Oryzias_latipes_hsok
ENSG00000205937	RNPS1	100	100.000	ENSOGAG00000031582	-	99	100.000	Otolemur_garnettii
ENSG00000205937	RNPS1	100	100.000	ENSOARG00000018056	-	81	99.310	Ovis_aries
ENSG00000205937	RNPS1	100	100.000	ENSPPAG00000037836	-	96	99.123	Pan_paniscus
ENSG00000205937	RNPS1	100	97.778	ENSPPAG00000011845	RNPS1	100	93.443	Pan_paniscus
ENSG00000205937	RNPS1	100	100.000	ENSPPRG00000011255	RNPS1	100	100.000	Panthera_pardus
ENSG00000205937	RNPS1	100	100.000	ENSPTIG00000015643	RNPS1	85	100.000	Panthera_tigris_altaica
ENSG00000205937	RNPS1	100	100.000	ENSPTRG00000046326	-	100	96.498	Pan_troglodytes
ENSG00000205937	RNPS1	100	100.000	ENSPTRG00000031310	RNPS1	100	100.000	Pan_troglodytes
ENSG00000205937	RNPS1	100	75.097	ENSPANG00000033576	-	100	75.097	Papio_anubis
ENSG00000205937	RNPS1	100	100.000	ENSPANG00000015748	RNPS1	100	100.000	Papio_anubis
ENSG00000205937	RNPS1	85	80.083	ENSPKIG00000023465	RNPS1	85	80.083	Paramormyrops_kingsleyae
ENSG00000205937	RNPS1	100	92.000	ENSPSIG00000006048	RNPS1	86	92.776	Pelodiscus_sinensis
ENSG00000205937	RNPS1	67	76.744	ENSPMGG00000015888	-	75	66.204	Periophthalmus_magnuspinnatus
ENSG00000205937	RNPS1	100	100.000	ENSPEMG00000012797	Rnps1	100	100.000	Peromyscus_maniculatus_bairdii
ENSG00000205937	RNPS1	100	100.000	ENSPCIG00000025012	RNPS1	100	98.227	Phascolarctos_cinereus
ENSG00000205937	RNPS1	100	96.875	ENSPCIG00000016114	-	80	98.387	Phascolarctos_cinereus
ENSG00000205937	RNPS1	86	63.699	ENSPFOG00000009978	RNPS1	75	63.889	Poecilia_formosa
ENSG00000205937	RNPS1	86	63.699	ENSPLAG00000009343	RNPS1	75	63.889	Poecilia_latipinna
ENSG00000205937	RNPS1	88	62.667	ENSPMEG00000008552	RNPS1	75	63.889	Poecilia_mexicana
ENSG00000205937	RNPS1	86	63.699	ENSPREG00000001843	RNPS1	75	63.889	Poecilia_reticulata
ENSG00000205937	RNPS1	100	100.000	ENSPCAG00000004514	RNPS1	100	97.705	Procavia_capensis
ENSG00000205937	RNPS1	100	100.000	ENSPCOG00000005478	RNPS1	100	100.000	Propithecus_coquereli
ENSG00000205937	RNPS1	100	100.000	ENSPVAG00000005105	RNPS1	100	99.672	Pteropus_vampyrus
ENSG00000205937	RNPS1	85	76.250	ENSPNAG00000025479	RNPS1	84	69.583	Pygocentrus_nattereri
ENSG00000205937	RNPS1	67	81.395	ENSPNAG00000017784	-	85	77.366	Pygocentrus_nattereri
ENSG00000205937	RNPS1	100	100.000	ENSRNOG00000008703	Rnps1	100	99.672	Rattus_norvegicus
ENSG00000205937	RNPS1	96	84.663	ENSRNOG00000027239	AABR07037800.1	65	84.653	Rattus_norvegicus
ENSG00000205937	RNPS1	80	81.553	ENSRBIG00000013248	-	64	82.258	Rhinopithecus_bieti
ENSG00000205937	RNPS1	99	99.288	ENSRBIG00000038965	-	99	99.288	Rhinopithecus_bieti
ENSG00000205937	RNPS1	100	100.000	ENSRROG00000041252	RNPS1	97	96.639	Rhinopithecus_roxellana
ENSG00000205937	RNPS1	100	100.000	ENSSBOG00000027927	RNPS1	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000205937	RNPS1	100	100.000	ENSSHAG00000016951	RNPS1	100	98.033	Sarcophilus_harrisii
ENSG00000205937	RNPS1	86	76.027	ENSSFOG00015022746	RNPS1	87	67.500	Scleropages_formosus
ENSG00000205937	RNPS1	85	76.987	ENSSFOG00015019341	-	75	69.295	Scleropages_formosus
ENSG00000205937	RNPS1	66	88.235	ENSSMAG00000005367	-	72	81.452	Scophthalmus_maximus
ENSG00000205937	RNPS1	85	70.539	ENSSMAG00000016933	RNPS1	50	65.068	Scophthalmus_maximus
ENSG00000205937	RNPS1	91	67.176	ENSSDUG00000006433	-	85	67.939	Seriola_dumerili
ENSG00000205937	RNPS1	85	70.833	ENSSDUG00000011453	RNPS1	84	71.369	Seriola_dumerili
ENSG00000205937	RNPS1	89	64.655	ENSSLDG00000021341	RNPS1	76	67.647	Seriola_lalandi_dorsalis
ENSG00000205937	RNPS1	100	95.858	ENSSARG00000001577	RNPS1	86	97.107	Sorex_araneus
ENSG00000205937	RNPS1	100	94.000	ENSSPUG00000016588	RNPS1	86	93.536	Sphenodon_punctatus
ENSG00000205937	RNPS1	66	78.824	ENSSPAG00000009383	RNPS1	84	71.784	Stegastes_partitus
ENSG00000205937	RNPS1	100	100.000	ENSSSCG00000008048	RNPS1	100	99.672	Sus_scrofa
ENSG00000205937	RNPS1	86	95.205	ENSTGUG00000003237	RNPS1	85	95.000	Taeniopygia_guttata
ENSG00000205937	RNPS1	85	71.784	ENSTRUG00000008602	RNPS1	84	71.784	Takifugu_rubripes
ENSG00000205937	RNPS1	85	72.083	ENSTNIG00000009753	RNPS1	84	72.016	Tetraodon_nigroviridis
ENSG00000205937	RNPS1	100	100.000	ENSTBEG00000009098	RNPS1	100	100.000	Tupaia_belangeri
ENSG00000205937	RNPS1	100	100.000	ENSTTRG00000008220	RNPS1	100	100.000	Tursiops_truncatus
ENSG00000205937	RNPS1	100	100.000	ENSUAMG00000004462	RNPS1	100	100.000	Ursus_americanus
ENSG00000205937	RNPS1	100	100.000	ENSUMAG00000022327	RNPS1	100	100.000	Ursus_maritimus
ENSG00000205937	RNPS1	100	100.000	ENSVVUG00000009244	RNPS1	100	100.000	Vulpes_vulpes
ENSG00000205937	RNPS1	92	64.744	ENSXETG00000024439	rnps1	73	72.124	Xenopus_tropicalis
ENSG00000205937	RNPS1	85	67.635	ENSXMAG00000004827	RNPS1	84	64.167	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	11546874.	IDA	Process
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	16209946.	IMP	Process
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	-	TAS	Process
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	21873635.	IBA	Process
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	22203037.	IMP	Process
GO:0000398	mRNA splicing, via spliceosome	21873635.	IBA	Process
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003723	RNA binding	22388736.	IDA	Function
GO:0003730	mRNA 3'-UTR binding	11546874.	IDA	Function
GO:0005515	protein binding	11477570.22365833.23602568.26496610.	IPI	Function
GO:0005634	nucleus	11546874.	IDA	Component
GO:0005654	nucleoplasm	21873635.	IBA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	11546874.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006351	transcription, DNA-templated	9580558.	TAS	Process
GO:0006405	RNA export from nucleus	-	TAS	Process
GO:0006406	mRNA export from nucleus	-	TAS	Process
GO:0008380	RNA splicing	21873635.	IBA	Process
GO:0016607	nuclear speck	-	IEA	Component
GO:0031124	mRNA 3'-end processing	-	TAS	Process
GO:0035145	exon-exon junction complex	11546874.	TAS	Component
GO:0043065	positive regulation of apoptotic process	12665594.	IDA	Process
GO:0048025	negative regulation of mRNA splicing, via spliceosome	12665594.	IDA	Process
GO:0061574	ASAP complex	21873635.	IBA	Component
GO:0061574	ASAP complex	12665594.	IDA	Component