EuRBPDB

Basic Information
Cancer Related Information

Description

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000206053 (Gene tree)
Gene ID: 90861
Gene Symbol: JPT2
Alias: FLJ13092|L11|KIAA1426|C16orf34|HN1L
Full Name: Jupiter microtubule associated homolog 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 24,025 bases
Position: chr16:1,678,256-1,702,280
Accession: 14137
RBP type: non-canonical RBP
Summary: (Jupiter Microtubule Associated Homolog 2) is a Protein Coding gene.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000566691	JPT2-208	601	-	ENSP00000454529	115 (aa)	-	H3BMT0
ENST00000382711	JPT2-203	894	-	ENSP00000372158	174 (aa)	-	Q9H910
ENST00000569256	JPT2-213	911	-	-	- (aa)	-	-
ENST00000562569	JPT2-205	458	-	ENSP00000457344	116 (aa)	-	H3BTV5
ENST00000565851	JPT2-207	565	-	ENSP00000457424	167 (aa)	-	H3BU16
ENST00000567717	JPT2-211	857	-	-	- (aa)	-	-
ENST00000566742	JPT2-209	593	-	ENSP00000454567	190 (aa)	-	H3BMV3
ENST00000248098	JPT2-201	3718	-	ENSP00000248098	190 (aa)	-	Q9H910
ENST00000566925	JPT2-210	570	-	ENSP00000456487	77 (aa)	-	H3BS08
ENST00000569765	JPT2-214	782	-	ENSP00000457536	98 (aa)	-	B4E1P3
ENST00000568376	JPT2-212	297	-	-	- (aa)	-	-
ENST00000382710	JPT2-202	962	-	ENSP00000372157	178 (aa)	-	A6NGP5
ENST00000562684	JPT2-206	3185	-	ENSP00000457694	218 (aa)	-	Q9H910
ENST00000561516	JPT2-204	1065	-	ENSP00000454459	70 (aa)	-	H3BMM8

Gene Model

Click here to download ENSG00000206053's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000206053's network

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000206053	JPT2	99	89.474	ENSMUSG00000024165	Jpt2	100	79.474	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005634	nucleus	-	IEA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005886	plasma membrane	-	IDA	Component

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
29249663	HN1L Promotes Triple-Negative Breast Cancer Stem Cells through LEPR-STAT3 Pathway.	Stem Cell Reports	2018 Jan 9	Liu Y	doi: 10.1016/j.stemcr.2017.11.010

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
BLCA	chr16	1691916	Silent	NA	G89G	0.18
BLCA	chr16	1698848	Missense_Mutation	novel	E141D	0.46
BLCA	chr16	1698953	Missense_Mutation	novel	K176N	0.11
BLCA	chr16	1691901	Silent	novel	L84L	0.61
BRCA	chr16	1699023	3'UTR	novel		0.27
BRCA	chr16	1685530	Missense_Mutation	NA	N46D	0.76
CESC	chr16	1691843	Missense_Mutation	NA	G65E	0.23
CESC	chr16	1700594	3'UTR	novel		0.44
CESC	chr16	1701158	3'UTR	novel		0.5
COAD	chr16	1699061	3'UTR	novel		0.43
COAD	chr16	1697849	Missense_Mutation	NA	S125L	0.09
COAD	chr16	1699122	3'UTR	novel		0.4
COAD	chr16	1685565	Missense_Mutation	novel	I57M	0.09
COAD	chr16	1697846	Missense_Mutation	NA	K124R	0.09
COAD	chr16	1697849	Missense_Mutation	NA	S125L	0.32
COAD	chr16	1685517	Silent	rs755954033	N41N	0.22
COAD	chr16	1698940	Missense_Mutation	novel	R172H	0.39
COAD	chr16	1691845	Missense_Mutation	NA	G66S	0.37
GBM	chr16	1691908	Missense_Mutation	novel	P87S	0.22
HNSC	chr16	1685474	Missense_Mutation	novel	L27R	0.45
HNSC	chr16	1698968	Silent	novel	P181P	0.17
HNSC	chr16	1691946	Silent	novel	V99V	0.26
HNSC	chr16	1697823	Missense_Mutation	NA	F116L	0.25
KIRC	chr16	1697809	Splice_Region	novel		0.2
KIRC	chr16	1698906	Missense_Mutation	NA	D161N	0.19
KIRP	chr16	1685485	Frame_Shift_Del	novel	*P31Qfs54**	0.66
LUAD	chr16	1698975	Nonsense_Mutation	novel	K184*	0.28
LUSC	chr16	1698880	Missense_Mutation	novel	K152M	0.21
LUSC	chr16	1691942	Missense_Mutation	novel	P98Q	0.18
LUSC	chr16	1698832	Missense_Mutation	NA	G136V	0.23
OV	chr16	1698988	In_Frame_Ins	novel	S188_F189insFQN	0.05
OV	chr16	1685504	Missense_Mutation	novel	S37C	0.06
OV	chr16	1685445	Missense_Mutation	novel	M17I	0.26
PAAD	chr16	1699046	3'UTR	novel		0.56
READ	chr16	1697849	Missense_Mutation	NA	S125L	0.42
SKCM	chr16	1698940	Missense_Mutation	novel	R172P	0.36
SKCM	chr16	1699066	3'UTR	novel		0.29
SKCM	chr16	1685480	Missense_Mutation	NA	G29E	0.36
SKCM	chr16	1699061	3'UTR	novel		0.38
SKCM	chr16	1685555	Missense_Mutation	novel	P54H	0.16
SKCM	chr16	1691880	Silent	NA	P77P	0.27
SKCM	chr16	1685500	Missense_Mutation	novel	P36S	0.23
SKCM	chr16	1698898	Missense_Mutation	NA	P158L	0.17
SKCM	chr16	1697839	Missense_Mutation	NA	E122K	0.3
TGCT	chr16	1698930	Missense_Mutation	novel	P169A	0.13
UCEC	chr16	1701338	3'UTR	novel		0.44
UCEC	chr16	1698826	Missense_Mutation	rs548126456	P134L	0.38
UCEC	chr16	1691890	Nonsense_Mutation	NA	R81*	0.19
UCEC	chr16	1698958	Missense_Mutation	NA	L178P	0.18
UCEC	chr16	1699016	3'UTR	novel		0.3
UCEC	chr16	1685754	Intron	novel		0.42
UCEC	chr16	1685466	Silent	rs775793002	S24S	0.42
UCEC	chr16	1701378	3'UTR	novel		0.14
UCEC	chr16	1691895	Silent	novel	Q82Q	0.28
UCEC	chr16	1691890	Nonsense_Mutation	NA	R81*	0.39
UCEC	chr16	1698863	Missense_Mutation	novel	R146S	0.07
UCEC	chr16	1685521	Missense_Mutation	NA	M43V	0.12
UCEC	chr16	1699130	3'UTR	novel		0.25
UCEC	chr16	1685481	Silent	novel	G29G	0.29
UCEC	chr16	1699057	3'UTR	novel		0.33
UCEC	chr16	1698931	Missense_Mutation	NA	P169L	0.38
UCEC	chr16	1698933	Missense_Mutation	NA	R170G	0.37
UCEC	chr16	1697849	Missense_Mutation	NA	S125L	0.48
UCEC	chr16	1698875	Silent	rs530937320	P150P	0.33

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	AMP	0.5444	0.22898
CHOL	DEL	0.1111	0.23475
ESCA	DEL	0.2826	0.012791
LUAD	DEL	0.126	0.1886
UCS	DEL	0.5179	0.13407

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0023	Kaplan-Meier Survival Analysis
SARC	0.0032	Kaplan-Meier Survival Analysis
MESO	0.00017	Kaplan-Meier Survival Analysis
ACC	0.00014	Kaplan-Meier Survival Analysis
HNSC	0.021	Kaplan-Meier Survival Analysis
SKCM	0.00011	Kaplan-Meier Survival Analysis
PRAD	0.05	Kaplan-Meier Survival Analysis
BRCA	0.032	Kaplan-Meier Survival Analysis
COAD	0.011	Kaplan-Meier Survival Analysis
PAAD	0.0022	Kaplan-Meier Survival Analysis
READ	0.0029	Kaplan-Meier Survival Analysis
LAML	0.021	Kaplan-Meier Survival Analysis
UCEC	0.0003	Kaplan-Meier Survival Analysis
LIHC	0.00064	Kaplan-Meier Survival Analysis
LGG	0.00011	Kaplan-Meier Survival Analysis
LUAD	0.013	Kaplan-Meier Survival Analysis
UVM	0.011	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742