EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000213246 (Gene tree)
Gene ID: 6827
Gene Symbol: SUPT4H1
Alias: SPT4H|Spt4|Supt4a|SUPT4H
Full Name: SPT4 homolog, DSIF elongation factor subunit
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 7,919 bases
Position: chr17:58,345,175-58,353,093
Accession: 11467
RBP type: canonical RBP
Summary: This gene encodes the small subunit of DRB (5,6-dichloro-1-beta-d-ribofuranosylbenzimidazole) sensitivity-inducing factor (DSIF) complex, which regulates mRNA processing and transcription elongation by RNA polymerase II. The encoded protein is localized to the nucleus and interacts with the large subunit (SUPT5H) to form the DSIF complex. Related pseudogenes have been identified on chromosomes 2 and 12. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000225504	Spt4	PF06093.13	4.2e-32	1	1
ENSP00000462670	Spt4	PF06093.13	4.2e-32	1	1
ENSP00000464618	Spt4	PF06093.13	2.3e-25	1	1
ENSP00000462100	Spt4	PF06093.13	6.7e-17	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
27376968	The yeast transcription elongation factor Spt4/5 is a sequence-specific RNA binding protein.	Protein Sci	2016 Sep	Blythe AJ	doi: 10.1002/pro.2976
10757782	Domains in the SPT5 protein that modulate its transcriptional regulatory properties.	Mol Cell Biol	2000 May	Ivanov D	-
26945063	Biochemical Analysis of Yeast Suppressor of Ty 4/5 (Spt4/5) Reveals the Importance of Nucleic Acid Interactions in the Prevention of RNA Polymerase II Arrest.	J Biol Chem	2016 May 6	Crickard JB	doi: 10.1074/jbc.M116.716001

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000581166	SUPT4H1-205	1401	-	-	- (aa)	-	-
ENST00000581204	SUPT4H1-206	539	-	-	- (aa)	-	-
ENST00000225504	SUPT4H1-201	1489	-	ENSP00000225504	117 (aa)	-	P63272
ENST00000577396	SUPT4H1-202	1643	-	ENSP00000462100	76 (aa)	-	D3DTZ5
ENST00000580947	SUPT4H1-204	574	-	ENSP00000462670	117 (aa)	-	P63272
ENST00000579289	SUPT4H1-203	318	-	ENSP00000462602	42 (aa)	-	J3KSQ6
ENST00000581540	SUPT4H1-207	668	-	ENSP00000464618	108 (aa)	-	J3QSB9

Gene Model

Click here to download ENSG00000213246's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000213246	rs2526376	17	58349781	A	General cognitive ability	29844566	z-score decrease	5.953	EFO_0004337
ENSG00000213246	rs2526376	17	58349781	A	Intelligence	29942086	z-score decrease	5.68	EFO_0004337
ENSG00000213246	rs757485	17	58347349	T	Intelligence	29942086	z-score decrease	5.529	EFO_0004337

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000213246's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000213246	SUPT4H1	100	86.842	ENSAPOG00000006828	supt4h1	100	87.234	Acanthochromis_polyacanthus
ENSG00000213246	SUPT4H1	100	99.145	ENSAMEG00000011686	SUPT4H1	100	99.145	Ailuropoda_melanoleuca
ENSG00000213246	SUPT4H1	100	86.842	ENSACIG00000012162	supt4h1	100	87.234	Amphilophus_citrinellus
ENSG00000213246	SUPT4H1	100	89.744	ENSAOCG00000022349	supt4h1	100	89.744	Amphiprion_ocellaris
ENSG00000213246	SUPT4H1	100	89.744	ENSAPEG00000013170	supt4h1	100	89.744	Amphiprion_percula
ENSG00000213246	SUPT4H1	100	89.744	ENSATEG00000005317	supt4h1	100	89.744	Anabas_testudineus
ENSG00000213246	SUPT4H1	100	98.684	ENSAPLG00000012497	SUPT4H1	100	83.051	Anas_platyrhynchos
ENSG00000213246	SUPT4H1	100	100.000	ENSANAG00000026628	SUPT4H1	100	99.145	Aotus_nancymaae
ENSG00000213246	SUPT4H1	100	90.598	ENSACLG00000005475	supt4h1	100	90.598	Astatotilapia_calliptera
ENSG00000213246	SUPT4H1	100	86.325	ENSAMXG00000041272	supt4h1	100	86.325	Astyanax_mexicanus
ENSG00000213246	SUPT4H1	90	58.095	WBGene00005014	spt-4	88	58.095	Caenorhabditis_elegans
ENSG00000213246	SUPT4H1	100	100.000	ENSCJAG00000017369	SUPT4H1	100	100.000	Callithrix_jacchus
ENSG00000213246	SUPT4H1	100	100.000	ENSCAFG00000017524	SUPT4H1	100	100.000	Canis_familiaris
ENSG00000213246	SUPT4H1	100	100.000	ENSCAFG00020025803	SUPT4H1	78	100.000	Canis_lupus_dingo
ENSG00000213246	SUPT4H1	100	100.000	ENSCHIG00000026783	SUPT4H1	100	100.000	Capra_hircus
ENSG00000213246	SUPT4H1	100	100.000	ENSTSYG00000030004	SUPT4H1	100	100.000	Carlito_syrichta
ENSG00000213246	SUPT4H1	100	100.000	ENSCPOG00000031227	SUPT4H1	100	100.000	Cavia_porcellus
ENSG00000213246	SUPT4H1	100	100.000	ENSCCAG00000034799	SUPT4H1	100	100.000	Cebus_capucinus
ENSG00000213246	SUPT4H1	100	100.000	ENSCATG00000042435	SUPT4H1	100	100.000	Cercocebus_atys
ENSG00000213246	SUPT4H1	93	80.282	ENSCATG00000024314	-	100	72.650	Cercocebus_atys
ENSG00000213246	SUPT4H1	100	100.000	ENSCLAG00000011223	SUPT4H1	100	100.000	Chinchilla_lanigera
ENSG00000213246	SUPT4H1	100	100.000	ENSCSAG00000005761	SUPT4H1	100	100.000	Chlorocebus_sabaeus
ENSG00000213246	SUPT4H1	100	83.761	ENSCHOG00000000246	SUPT4H1	100	83.761	Choloepus_hoffmanni
ENSG00000213246	SUPT4H1	57	95.833	ENSCPBG00000015876	SUPT4H1	100	100.000	Chrysemys_picta_bellii
ENSG00000213246	SUPT4H1	98	71.304	ENSCING00000019520	spt4	94	71.304	Ciona_intestinalis
ENSG00000213246	SUPT4H1	98	72.174	ENSCSAVG00000009479	-	94	72.174	Ciona_savignyi
ENSG00000213246	SUPT4H1	100	100.000	ENSCANG00000034430	SUPT4H1	100	100.000	Colobus_angolensis_palliatus
ENSG00000213246	SUPT4H1	100	100.000	ENSCGRG00001018056	Supt4a	100	99.145	Cricetulus_griseus_chok1gshd
ENSG00000213246	SUPT4H1	100	100.000	ENSCGRG00000014047	Supt4a	100	99.145	Cricetulus_griseus_crigri
ENSG00000213246	SUPT4H1	100	88.889	ENSCSEG00000010897	supt4h1	100	88.889	Cynoglossus_semilaevis
ENSG00000213246	SUPT4H1	100	89.744	ENSCVAG00000014190	supt4h1	100	89.744	Cyprinodon_variegatus
ENSG00000213246	SUPT4H1	100	88.034	ENSDARG00000113969	supt4h1	100	88.034	Danio_rerio
ENSG00000213246	SUPT4H1	100	100.000	ENSDNOG00000032349	SUPT4H1	100	100.000	Dasypus_novemcinctus
ENSG00000213246	SUPT4H1	100	100.000	ENSDORG00000002826	-	100	100.000	Dipodomys_ordii
ENSG00000213246	SUPT4H1	91	89.855	ENSDORG00000030049	-	100	86.957	Dipodomys_ordii
ENSG00000213246	SUPT4H1	96	62.500	FBgn0028683	spt4	97	62.500	Drosophila_melanogaster
ENSG00000213246	SUPT4H1	100	80.263	ENSEBUG00000006884	supt4h1	100	80.263	Eptatretus_burgeri
ENSG00000213246	SUPT4H1	100	100.000	ENSEASG00005002787	SUPT4H1	80	100.000	Equus_asinus_asinus
ENSG00000213246	SUPT4H1	100	100.000	ENSECAG00000016585	SUPT4H1	100	100.000	Equus_caballus
ENSG00000213246	SUPT4H1	100	88.889	ENSELUG00000019831	supt4h1	100	88.889	Esox_lucius
ENSG00000213246	SUPT4H1	100	100.000	ENSFCAG00000018732	SUPT4H1	100	100.000	Felis_catus
ENSG00000213246	SUPT4H1	100	96.053	ENSFALG00000013757	SUPT4H1	100	94.681	Ficedula_albicollis
ENSG00000213246	SUPT4H1	100	100.000	ENSFDAG00000016718	SUPT4H1	100	99.145	Fukomys_damarensis
ENSG00000213246	SUPT4H1	100	90.598	ENSFHEG00000009114	supt4h1	100	90.598	Fundulus_heteroclitus
ENSG00000213246	SUPT4H1	100	86.325	ENSGMOG00000014619	supt4h1	100	86.325	Gadus_morhua
ENSG00000213246	SUPT4H1	100	98.684	ENSGALG00000000944	SUPT4H1	100	97.436	Gallus_gallus
ENSG00000213246	SUPT4H1	100	88.889	ENSGAFG00000014374	supt4h1	100	88.889	Gambusia_affinis
ENSG00000213246	SUPT4H1	100	88.034	ENSGACG00000020237	supt4h1	100	88.034	Gasterosteus_aculeatus
ENSG00000213246	SUPT4H1	57	95.833	ENSGAGG00000008561	SUPT4H1	57	91.045	Gopherus_agassizii
ENSG00000213246	SUPT4H1	100	100.000	ENSGGOG00000007232	SUPT4H1	100	100.000	Gorilla_gorilla
ENSG00000213246	SUPT4H1	100	86.842	ENSHBUG00000000848	-	89	87.619	Haplochromis_burtoni
ENSG00000213246	SUPT4H1	100	88.158	ENSHBUG00000022528	supt4h1	100	88.298	Haplochromis_burtoni
ENSG00000213246	SUPT4H1	100	100.000	ENSHGLG00000005007	SUPT4H1	100	99.145	Heterocephalus_glaber_female
ENSG00000213246	SUPT4H1	100	100.000	ENSHGLG00100018961	SUPT4H1	100	99.145	Heterocephalus_glaber_male
ENSG00000213246	SUPT4H1	100	87.179	ENSHCOG00000010739	supt4h1	100	87.179	Hippocampus_comes
ENSG00000213246	SUPT4H1	100	87.179	ENSIPUG00000012062	supt4h1	100	87.179	Ictalurus_punctatus
ENSG00000213246	SUPT4H1	100	78.512	ENSSTOG00000032338	SUPT4H1	100	78.512	Ictidomys_tridecemlineatus
ENSG00000213246	SUPT4H1	100	100.000	ENSJJAG00000010938	Supt4a	100	100.000	Jaculus_jaculus
ENSG00000213246	SUPT4H1	100	88.889	ENSKMAG00000013119	supt4h1	100	88.889	Kryptolebias_marmoratus
ENSG00000213246	SUPT4H1	100	88.889	ENSLBEG00000018308	supt4h1	100	88.889	Labrus_bergylta
ENSG00000213246	SUPT4H1	100	93.162	ENSLACG00000016364	SUPT4H1	100	93.162	Latimeria_chalumnae
ENSG00000213246	SUPT4H1	100	93.162	ENSLOCG00000002970	supt4h1	100	93.162	Lepisosteus_oculatus
ENSG00000213246	SUPT4H1	100	100.000	ENSLAFG00000020718	SUPT4H1	100	100.000	Loxodonta_africana
ENSG00000213246	SUPT4H1	93	80.282	ENSMFAG00000045087	-	100	72.650	Macaca_fascicularis
ENSG00000213246	SUPT4H1	100	100.000	ENSMFAG00000003856	SUPT4H1	100	100.000	Macaca_fascicularis
ENSG00000213246	SUPT4H1	93	80.282	ENSMMUG00000049176	-	100	72.650	Macaca_mulatta
ENSG00000213246	SUPT4H1	100	100.000	ENSMMUG00000040655	SUPT4H1	100	100.000	Macaca_mulatta
ENSG00000213246	SUPT4H1	92	88.571	ENSMNEG00000032891	-	100	72.650	Macaca_nemestrina
ENSG00000213246	SUPT4H1	100	100.000	ENSMNEG00000037471	SUPT4H1	100	100.000	Macaca_nemestrina
ENSG00000213246	SUPT4H1	93	78.873	ENSMNEG00000034957	-	100	71.795	Macaca_nemestrina
ENSG00000213246	SUPT4H1	100	100.000	ENSMLEG00000013750	SUPT4H1	100	100.000	Mandrillus_leucophaeus
ENSG00000213246	SUPT4H1	100	68.376	ENSMLEG00000031477	-	100	68.376	Mandrillus_leucophaeus
ENSG00000213246	SUPT4H1	96	87.671	ENSMLEG00000040145	-	100	76.923	Mandrillus_leucophaeus
ENSG00000213246	SUPT4H1	100	89.744	ENSMAMG00000006148	supt4h1	100	89.744	Mastacembelus_armatus
ENSG00000213246	SUPT4H1	100	90.598	ENSMZEG00005023783	supt4h1	100	90.598	Maylandia_zebra
ENSG00000213246	SUPT4H1	100	100.000	ENSMAUG00000013090	Supt4a	100	99.145	Mesocricetus_auratus
ENSG00000213246	SUPT4H1	100	100.000	ENSMICG00000043219	SUPT4H1	100	100.000	Microcebus_murinus
ENSG00000213246	SUPT4H1	100	100.000	ENSMOCG00000005545	Supt4a	100	99.145	Microtus_ochrogaster
ENSG00000213246	SUPT4H1	100	86.842	ENSMMOG00000005411	supt4h1	100	87.234	Mola_mola
ENSG00000213246	SUPT4H1	100	96.581	ENSMODG00000024938	-	100	96.581	Monodelphis_domestica
ENSG00000213246	SUPT4H1	100	82.906	ENSMODG00000024427	-	100	82.906	Monodelphis_domestica
ENSG00000213246	SUPT4H1	100	90.598	ENSMALG00000013156	supt4h1	100	90.598	Monopterus_albus
ENSG00000213246	SUPT4H1	100	100.000	ENSMUSG00000020485	Supt4a	100	100.000	Mus_musculus
ENSG00000213246	SUPT4H1	100	100.000	ENSMPUG00000015326	SUPT4H1	98	100.000	Mustela_putorius_furo
ENSG00000213246	SUPT4H1	100	93.162	ENSMLUG00000027172	-	100	93.162	Myotis_lucifugus
ENSG00000213246	SUPT4H1	100	93.421	ENSMLUG00000028057	-	100	93.162	Myotis_lucifugus
ENSG00000213246	SUPT4H1	100	100.000	ENSMLUG00000025583	-	100	100.000	Myotis_lucifugus
ENSG00000213246	SUPT4H1	100	94.872	ENSMLUG00000024867	-	100	94.872	Myotis_lucifugus
ENSG00000213246	SUPT4H1	99	78.667	ENSNGAG00000014401	-	99	78.667	Nannospalax_galili
ENSG00000213246	SUPT4H1	100	100.000	ENSNGAG00000015537	-	100	100.000	Nannospalax_galili
ENSG00000213246	SUPT4H1	100	90.598	ENSNBRG00000016146	supt4h1	100	90.598	Neolamprologus_brichardi
ENSG00000213246	SUPT4H1	97	70.175	ENSNLEG00000028366	-	80	70.175	Nomascus_leucogenys
ENSG00000213246	SUPT4H1	100	100.000	ENSNLEG00000008159	-	100	100.000	Nomascus_leucogenys
ENSG00000213246	SUPT4H1	100	94.737	ENSNLEG00000033851	-	98	87.037	Nomascus_leucogenys
ENSG00000213246	SUPT4H1	100	97.436	ENSMEUG00000010164	SUPT4H1	100	97.436	Notamacropus_eugenii
ENSG00000213246	SUPT4H1	76	100.000	ENSOPRG00000018779	-	100	69.231	Ochotona_princeps
ENSG00000213246	SUPT4H1	100	100.000	ENSODEG00000011183	SUPT4H1	100	100.000	Octodon_degus
ENSG00000213246	SUPT4H1	100	100.000	ENSOCUG00000025823	SUPT4H1	100	100.000	Oryctolagus_cuniculus
ENSG00000213246	SUPT4H1	100	90.598	ENSORLG00000011097	supt4h1	100	90.598	Oryzias_latipes
ENSG00000213246	SUPT4H1	100	90.598	ENSORLG00020018918	supt4h1	100	90.598	Oryzias_latipes_hni
ENSG00000213246	SUPT4H1	100	90.598	ENSORLG00015001908	supt4h1	100	90.598	Oryzias_latipes_hsok
ENSG00000213246	SUPT4H1	100	90.598	ENSOMEG00000009103	supt4h1	100	90.598	Oryzias_melastigma
ENSG00000213246	SUPT4H1	100	100.000	ENSOGAG00000031972	SUPT4H1	100	100.000	Otolemur_garnettii
ENSG00000213246	SUPT4H1	100	100.000	ENSOARG00000010021	SUPT4H1	100	100.000	Ovis_aries
ENSG00000213246	SUPT4H1	100	100.000	ENSPPRG00000010997	SUPT4H1	100	100.000	Panthera_pardus
ENSG00000213246	SUPT4H1	100	100.000	ENSPTIG00000006503	SUPT4H1	100	100.000	Panthera_tigris_altaica
ENSG00000213246	SUPT4H1	100	100.000	ENSPTRG00000009451	SUPT4H1	100	100.000	Pan_troglodytes
ENSG00000213246	SUPT4H1	100	71.795	ENSPANG00000031534	-	100	71.795	Papio_anubis
ENSG00000213246	SUPT4H1	100	100.000	ENSPANG00000022280	SUPT4H1	100	100.000	Papio_anubis
ENSG00000213246	SUPT4H1	100	79.487	ENSPKIG00000017008	supt4h1	100	79.487	Paramormyrops_kingsleyae
ENSG00000213246	SUPT4H1	100	98.684	ENSPSIG00000008272	SUPT4H1	100	95.918	Pelodiscus_sinensis
ENSG00000213246	SUPT4H1	100	88.158	ENSPMGG00000013558	supt4h1	98	88.421	Periophthalmus_magnuspinnatus
ENSG00000213246	SUPT4H1	100	100.000	ENSPEMG00000001651	Supt4a	100	99.145	Peromyscus_maniculatus_bairdii
ENSG00000213246	SUPT4H1	100	97.436	ENSPCIG00000015610	-	100	97.436	Phascolarctos_cinereus
ENSG00000213246	SUPT4H1	82	83.871	ENSPCIG00000007509	-	80	79.121	Phascolarctos_cinereus
ENSG00000213246	SUPT4H1	100	88.889	ENSPFOG00000018406	supt4h1	100	88.889	Poecilia_formosa
ENSG00000213246	SUPT4H1	100	88.889	ENSPLAG00000012498	supt4h1	100	88.889	Poecilia_latipinna
ENSG00000213246	SUPT4H1	100	88.889	ENSPMEG00000011887	supt4h1	100	88.889	Poecilia_mexicana
ENSG00000213246	SUPT4H1	100	85.526	ENSPREG00000008031	supt4h1	87	80.734	Poecilia_reticulata
ENSG00000213246	SUPT4H1	100	100.000	ENSPPYG00000008233	SUPT4H1	100	100.000	Pongo_abelii
ENSG00000213246	SUPT4H1	76	100.000	ENSPCAG00000011213	-	100	100.000	Procavia_capensis
ENSG00000213246	SUPT4H1	100	100.000	ENSPCOG00000016589	SUPT4H1	100	100.000	Propithecus_coquereli
ENSG00000213246	SUPT4H1	100	100.000	ENSPVAG00000002320	SUPT4H1	100	100.000	Pteropus_vampyrus
ENSG00000213246	SUPT4H1	100	90.598	ENSPNYG00000016837	supt4h1	100	90.598	Pundamilia_nyererei
ENSG00000213246	SUPT4H1	100	85.526	ENSPNAG00000009422	supt4h1	100	87.234	Pygocentrus_nattereri
ENSG00000213246	SUPT4H1	100	100.000	ENSRNOG00000007845	Supt4h1	100	100.000	Rattus_norvegicus
ENSG00000213246	SUPT4H1	100	100.000	ENSRBIG00000043489	SUPT4H1	100	100.000	Rhinopithecus_bieti
ENSG00000213246	SUPT4H1	100	100.000	ENSRROG00000045659	SUPT4H1	100	100.000	Rhinopithecus_roxellana
ENSG00000213246	SUPT4H1	85	43.434	YGR063C	-	91	43.434	Saccharomyces_cerevisiae
ENSG00000213246	SUPT4H1	100	100.000	ENSSBOG00000031578	SUPT4H1	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000213246	SUPT4H1	100	86.842	ENSSFOG00015001230	supt4h1	100	86.842	Scleropages_formosus
ENSG00000213246	SUPT4H1	100	90.598	ENSSMAG00000000422	supt4h1	100	90.598	Scophthalmus_maximus
ENSG00000213246	SUPT4H1	100	90.598	ENSSDUG00000017639	supt4h1	100	90.598	Seriola_dumerili
ENSG00000213246	SUPT4H1	100	90.598	ENSSLDG00000019831	supt4h1	100	90.598	Seriola_lalandi_dorsalis
ENSG00000213246	SUPT4H1	100	97.436	ENSSPUG00000001513	SUPT4H1	100	97.436	Sphenodon_punctatus
ENSG00000213246	SUPT4H1	100	90.598	ENSSPAG00000017849	supt4h1	100	90.598	Stegastes_partitus
ENSG00000213246	SUPT4H1	100	100.000	ENSSSCG00000034752	SUPT4H1	100	100.000	Sus_scrofa
ENSG00000213246	SUPT4H1	76	94.828	ENSTGUG00000003297	SUPT4H1	100	94.828	Taeniopygia_guttata
ENSG00000213246	SUPT4H1	100	88.889	ENSTRUG00000021118	supt4h1	100	88.889	Takifugu_rubripes
ENSG00000213246	SUPT4H1	100	88.889	ENSTNIG00000008553	supt4h1	100	88.889	Tetraodon_nigroviridis
ENSG00000213246	SUPT4H1	100	100.000	ENSUAMG00000005160	SUPT4H1	100	100.000	Ursus_americanus
ENSG00000213246	SUPT4H1	100	100.000	ENSUMAG00000022805	SUPT4H1	100	100.000	Ursus_maritimus
ENSG00000213246	SUPT4H1	100	100.000	ENSVPAG00000009628	SUPT4H1	100	100.000	Vicugna_pacos
ENSG00000213246	SUPT4H1	100	100.000	ENSVVUG00000012505	SUPT4H1	100	100.000	Vulpes_vulpes
ENSG00000213246	SUPT4H1	100	77.966	ENSXETG00000025331	supt4h1	100	77.966	Xenopus_tropicalis
ENSG00000213246	SUPT4H1	100	85.526	ENSXCOG00000005652	supt4h1	100	86.170	Xiphophorus_couchianus
ENSG00000213246	SUPT4H1	100	88.889	ENSXMAG00000005633	supt4h1	100	88.889	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000122	negative regulation of transcription by RNA polymerase II	9450929.9857195.	IDA	Process
GO:0000993	RNA polymerase II complex binding	21873635.	IBA	Function
GO:0003700	DNA-binding transcription factor activity	8649394.	TAS	Function
GO:0003727	single-stranded RNA binding	21873635.	IBA	Function
GO:0005515	protein binding	10075709.17404243.25416956.26496610.26789250.27107012.	IPI	Function
GO:0005634	nucleus	8649394.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0006325	chromatin organization	21873635.	IBA	Process
GO:0006338	chromatin remodeling	8649394.	TAS	Process
GO:0006355	regulation of transcription, DNA-templated	8786137.	TAS	Process
GO:0006357	regulation of transcription by RNA polymerase II	8649394.	TAS	Process
GO:0006366	transcription by RNA polymerase II	-	TAS	Process
GO:0006368	transcription elongation from RNA polymerase II promoter	9450929.9857195.	IDA	Process
GO:0006368	transcription elongation from RNA polymerase II promoter	-	TAS	Process
GO:0008270	zinc ion binding	-	IEA	Function
GO:0032044	DSIF complex	21873635.	IBA	Component
GO:0032044	DSIF complex	9450929.	IDA	Component
GO:0032785	negative regulation of DNA-templated transcription, elongation	9450929.9857195.	IDA	Process
GO:0032786	positive regulation of DNA-templated transcription, elongation	9450929.	IDA	Process
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	-	IEA	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	9450929.	IDA	Process
GO:0046982	protein heterodimerization activity	9450929.	IPI	Function
GO:0050434	positive regulation of viral transcription	-	TAS	Process