EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000223496 (Gene tree)
Gene ID: 118460
Gene Symbol: EXOSC6
Alias: MTR3|hMtr3p|Mtr3p|EAP4|p11
Full Name: exosome component 6
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 5,153 bases
Position: chr16:70,246,778-70,251,930
Accession: 19055
RBP type: canonical RBP
Summary: This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000398597	RNase_PH	PF01138.21	5.5e-27	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
1717937	Drosophila snRNP associated protein P11 which specifically binds to heat shock puff 93D reveals strong homology with hnRNP core protein A1.	Nucleic Acids Res	1991 Sep 25	Hovemann BT	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000435634	EXOSC6-201	5153	-	ENSP00000398597	272 (aa)	-	Q5RKV6

Gene Model

Click here to download ENSG00000223496's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03018	RNA degradation	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000223496's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000223496	EXOSC6	70	34.555	ENSG00000178896	EXOSC4	72	34.392

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000223496	EXOSC6	97	43.262	ENSAPOG00000022329	exosc6	95	42.909	Acanthochromis_polyacanthus
ENSG00000223496	EXOSC6	72	34.184	ENSAPOG00000000255	exosc4	74	34.021	Acanthochromis_polyacanthus
ENSG00000223496	EXOSC6	70	34.031	ENSAMEG00000006093	EXOSC4	72	33.862	Ailuropoda_melanoleuca
ENSG00000223496	EXOSC6	97	43.662	ENSACIG00000016636	exosc6	95	43.165	Amphilophus_citrinellus
ENSG00000223496	EXOSC6	72	34.184	ENSACIG00000017924	exosc4	74	34.021	Amphilophus_citrinellus
ENSG00000223496	EXOSC6	97	43.617	ENSAOCG00000006951	exosc6	95	43.273	Amphiprion_ocellaris
ENSG00000223496	EXOSC6	72	34.848	ENSAOCG00000005105	exosc4	74	34.021	Amphiprion_ocellaris
ENSG00000223496	EXOSC6	72	34.848	ENSAPEG00000003972	exosc4	74	34.021	Amphiprion_percula
ENSG00000223496	EXOSC6	97	43.617	ENSAPEG00000022951	exosc6	95	43.273	Amphiprion_percula
ENSG00000223496	EXOSC6	72	34.343	ENSATEG00000007766	exosc4	74	33.505	Anabas_testudineus
ENSG00000223496	EXOSC6	97	44.128	ENSATEG00000014148	exosc6	95	43.431	Anabas_testudineus
ENSG00000223496	EXOSC6	59	33.537	ENSACAG00000004017	EXOSC4	83	31.902	Anolis_carolinensis
ENSG00000223496	EXOSC6	70	34.555	ENSANAG00000026123	EXOSC4	72	34.392	Aotus_nancymaae
ENSG00000223496	EXOSC6	96	83.462	ENSANAG00000009362	EXOSC6	95	85.000	Aotus_nancymaae
ENSG00000223496	EXOSC6	72	33.673	ENSACLG00000020071	exosc4	74	33.505	Astatotilapia_calliptera
ENSG00000223496	EXOSC6	97	42.908	ENSACLG00000022304	exosc6	95	42.754	Astatotilapia_calliptera
ENSG00000223496	EXOSC6	98	46.071	ENSAMXG00000026269	exosc6	96	45.255	Astyanax_mexicanus
ENSG00000223496	EXOSC6	67	34.426	ENSAMXG00000030867	exosc4	74	33.505	Astyanax_mexicanus
ENSG00000223496	EXOSC6	96	93.462	ENSBTAG00000053923	EXOSC6	96	93.462	Bos_taurus
ENSG00000223496	EXOSC6	70	34.555	ENSBTAG00000014607	EXOSC4	72	34.392	Bos_taurus
ENSG00000223496	EXOSC6	99	97.398	ENSCJAG00000014559	EXOSC6	99	97.398	Callithrix_jacchus
ENSG00000223496	EXOSC6	70	34.555	ENSCJAG00000021458	EXOSC4	72	34.392	Callithrix_jacchus
ENSG00000223496	EXOSC6	70	34.031	ENSCAFG00000001521	EXOSC4	72	33.862	Canis_familiaris
ENSG00000223496	EXOSC6	96	95.769	ENSCAFG00020020974	EXOSC6	96	95.769	Canis_lupus_dingo
ENSG00000223496	EXOSC6	70	34.031	ENSCAFG00020018820	EXOSC4	72	33.862	Canis_lupus_dingo
ENSG00000223496	EXOSC6	96	95.000	ENSCHIG00000007389	EXOSC6	96	95.000	Capra_hircus
ENSG00000223496	EXOSC6	70	34.555	ENSCHIG00000021121	EXOSC4	72	34.392	Capra_hircus
ENSG00000223496	EXOSC6	70	34.555	ENSTSYG00000029697	EXOSC4	72	34.392	Carlito_syrichta
ENSG00000223496	EXOSC6	96	83.077	ENSCPOG00000002371	-	95	83.077	Cavia_porcellus
ENSG00000223496	EXOSC6	70	34.031	ENSCPOG00000022671	EXOSC4	72	33.862	Cavia_porcellus
ENSG00000223496	EXOSC6	99	84.387	ENSCPOG00000037814	-	96	85.000	Cavia_porcellus
ENSG00000223496	EXOSC6	53	34.459	ENSCCAG00000025515	EXOSC4	62	33.333	Cebus_capucinus
ENSG00000223496	EXOSC6	70	34.555	ENSCATG00000029965	EXOSC4	72	34.392	Cercocebus_atys
ENSG00000223496	EXOSC6	69	94.872	ENSCLAG00000004121	EXOSC6	86	95.455	Chinchilla_lanigera
ENSG00000223496	EXOSC6	70	34.555	ENSCLAG00000014676	EXOSC4	72	34.392	Chinchilla_lanigera
ENSG00000223496	EXOSC6	70	34.555	ENSCSAG00000008802	EXOSC4	72	34.392	Chlorocebus_sabaeus
ENSG00000223496	EXOSC6	82	32.889	ENSCPBG00000018860	EXOSC4	85	31.390	Chrysemys_picta_bellii
ENSG00000223496	EXOSC6	97	32.509	ENSCING00000013458	-	94	32.734	Ciona_intestinalis
ENSG00000223496	EXOSC6	83	31.004	ENSCING00000009562	-	87	31.579	Ciona_intestinalis
ENSG00000223496	EXOSC6	97	34.507	ENSCSAVG00000002563	-	98	35.357	Ciona_savignyi
ENSG00000223496	EXOSC6	85	32.353	ENSCSAVG00000008006	-	87	31.624	Ciona_savignyi
ENSG00000223496	EXOSC6	70	34.555	ENSCANG00000035733	EXOSC4	72	34.392	Colobus_angolensis_palliatus
ENSG00000223496	EXOSC6	70	34.555	ENSCGRG00001020452	Exosc4	72	34.392	Cricetulus_griseus_chok1gshd
ENSG00000223496	EXOSC6	96	93.846	ENSCGRG00001000899	Exosc6	96	93.846	Cricetulus_griseus_chok1gshd
ENSG00000223496	EXOSC6	70	34.555	ENSCGRG00000016505	Exosc4	72	34.392	Cricetulus_griseus_crigri
ENSG00000223496	EXOSC6	72	33.673	ENSCSEG00000010906	exosc4	74	33.505	Cynoglossus_semilaevis
ENSG00000223496	EXOSC6	97	38.078	ENSCSEG00000014277	exosc6	95	37.591	Cynoglossus_semilaevis
ENSG00000223496	EXOSC6	71	33.163	ENSCVAG00000006625	exosc4	74	32.474	Cyprinodon_variegatus
ENSG00000223496	EXOSC6	63	46.067	ENSCVAG00000021002	EXOSC6	85	46.243	Cyprinodon_variegatus
ENSG00000223496	EXOSC6	63	46.067	ENSCVAG00000021030	exosc6	84	46.243	Cyprinodon_variegatus
ENSG00000223496	EXOSC6	85	32.328	ENSDARG00000103432	exosc4	75	34.021	Danio_rerio
ENSG00000223496	EXOSC6	98	45.000	ENSDARG00000036060	exosc6	96	45.255	Danio_rerio
ENSG00000223496	EXOSC6	70	34.555	ENSDNOG00000009800	EXOSC4	72	34.392	Dasypus_novemcinctus
ENSG00000223496	EXOSC6	96	96.538	ENSDNOG00000032035	EXOSC6	96	96.538	Dasypus_novemcinctus
ENSG00000223496	EXOSC6	70	34.031	ENSDORG00000008461	Exosc4	72	33.862	Dipodomys_ordii
ENSG00000223496	EXOSC6	88	31.535	FBgn0032487	Ski6	86	32.174	Drosophila_melanogaster
ENSG00000223496	EXOSC6	83	31.441	ENSEBUG00000014277	exosc4	74	31.443	Eptatretus_burgeri
ENSG00000223496	EXOSC6	99	97.037	ENSEASG00005013410	EXOSC6	99	97.037	Equus_asinus_asinus
ENSG00000223496	EXOSC6	70	34.555	ENSEASG00005010166	EXOSC4	72	34.392	Equus_asinus_asinus
ENSG00000223496	EXOSC6	99	97.407	ENSECAG00000039860	EXOSC6	99	97.407	Equus_caballus
ENSG00000223496	EXOSC6	70	34.555	ENSECAG00000013658	EXOSC4	72	34.392	Equus_caballus
ENSG00000223496	EXOSC6	98	44.056	ENSELUG00000015515	exosc6	96	43.929	Esox_lucius
ENSG00000223496	EXOSC6	69	33.511	ENSELUG00000021011	exosc4	71	33.511	Esox_lucius
ENSG00000223496	EXOSC6	70	34.031	ENSFCAG00000034465	EXOSC4	72	33.862	Felis_catus
ENSG00000223496	EXOSC6	96	95.769	ENSFCAG00000046021	EXOSC6	96	95.769	Felis_catus
ENSG00000223496	EXOSC6	70	34.555	ENSFDAG00000006708	EXOSC4	72	34.392	Fukomys_damarensis
ENSG00000223496	EXOSC6	97	45.936	ENSFHEG00000017490	exosc6	95	45.683	Fundulus_heteroclitus
ENSG00000223496	EXOSC6	71	34.184	ENSFHEG00000013533	exosc4	74	33.505	Fundulus_heteroclitus
ENSG00000223496	EXOSC6	100	45.139	ENSGMOG00000008151	exosc6	95	44.928	Gadus_morhua
ENSG00000223496	EXOSC6	85	31.330	ENSGMOG00000002113	exosc4	72	33.505	Gadus_morhua
ENSG00000223496	EXOSC6	83	45.228	ENSGAFG00000015179	exosc6	86	44.770	Gambusia_affinis
ENSG00000223496	EXOSC6	83	31.602	ENSGAFG00000021407	exosc4	74	33.505	Gambusia_affinis
ENSG00000223496	EXOSC6	97	45.196	ENSGACG00000002690	exosc6	95	45.455	Gasterosteus_aculeatus
ENSG00000223496	EXOSC6	72	34.184	ENSGACG00000017838	exosc4	72	34.021	Gasterosteus_aculeatus
ENSG00000223496	EXOSC6	70	34.555	ENSGGOG00000040193	-	72	34.392	Gorilla_gorilla
ENSG00000223496	EXOSC6	70	34.555	ENSGGOG00000044212	-	72	34.392	Gorilla_gorilla
ENSG00000223496	EXOSC6	72	33.673	ENSHBUG00000006605	exosc4	74	33.505	Haplochromis_burtoni
ENSG00000223496	EXOSC6	97	42.908	ENSHBUG00000011123	exosc6	95	42.754	Haplochromis_burtoni
ENSG00000223496	EXOSC6	70	34.555	ENSHGLG00000016299	EXOSC4	72	34.392	Heterocephalus_glaber_female
ENSG00000223496	EXOSC6	96	92.692	ENSHGLG00000021313	EXOSC6	96	92.692	Heterocephalus_glaber_female
ENSG00000223496	EXOSC6	57	94.366	ENSHGLG00100014981	EXOSC6	85	94.366	Heterocephalus_glaber_male
ENSG00000223496	EXOSC6	70	34.555	ENSHGLG00100018786	EXOSC4	72	34.392	Heterocephalus_glaber_male
ENSG00000223496	EXOSC6	72	33.163	ENSHCOG00000018875	exosc4	70	32.990	Hippocampus_comes
ENSG00000223496	EXOSC6	97	43.060	ENSHCOG00000012112	exosc6	95	42.909	Hippocampus_comes
ENSG00000223496	EXOSC6	69	34.043	ENSIPUG00000011922	Exosc4	74	33.505	Ictalurus_punctatus
ENSG00000223496	EXOSC6	97	46.739	ENSIPUG00000004761	exosc6	95	46.154	Ictalurus_punctatus
ENSG00000223496	EXOSC6	96	94.231	ENSSTOG00000006849	EXOSC6	96	94.231	Ictidomys_tridecemlineatus
ENSG00000223496	EXOSC6	70	36.269	ENSSTOG00000002632	EXOSC4	72	34.737	Ictidomys_tridecemlineatus
ENSG00000223496	EXOSC6	58	94.366	ENSJJAG00000003460	Exosc6	94	60.769	Jaculus_jaculus
ENSG00000223496	EXOSC6	70	34.555	ENSJJAG00000009655	Exosc4	72	34.392	Jaculus_jaculus
ENSG00000223496	EXOSC6	97	45.652	ENSKMAG00000009821	exosc6	95	45.387	Kryptolebias_marmoratus
ENSG00000223496	EXOSC6	86	31.799	ENSKMAG00000015373	exosc4	74	32.474	Kryptolebias_marmoratus
ENSG00000223496	EXOSC6	72	34.184	ENSLBEG00000012754	exosc4	74	32.990	Labrus_bergylta
ENSG00000223496	EXOSC6	96	42.391	ENSLBEG00000018680	exosc6	82	42.545	Labrus_bergylta
ENSG00000223496	EXOSC6	72	33.673	ENSLOCG00000008878	exosc4	74	32.474	Lepisosteus_oculatus
ENSG00000223496	EXOSC6	98	46.127	ENSLOCG00000017597	exosc6	95	45.848	Lepisosteus_oculatus
ENSG00000223496	EXOSC6	70	34.555	ENSLAFG00000030187	EXOSC4	72	34.392	Loxodonta_africana
ENSG00000223496	EXOSC6	100	97.426	ENSMFAG00000035562	EXOSC6	100	97.426	Macaca_fascicularis
ENSG00000223496	EXOSC6	70	34.555	ENSMFAG00000000161	EXOSC4	72	34.392	Macaca_fascicularis
ENSG00000223496	EXOSC6	70	34.555	ENSMMUG00000007160	EXOSC4	72	34.392	Macaca_mulatta
ENSG00000223496	EXOSC6	100	98.162	ENSMMUG00000048384	EXOSC6	100	98.162	Macaca_mulatta
ENSG00000223496	EXOSC6	70	34.555	ENSMNEG00000033938	EXOSC4	72	34.392	Macaca_nemestrina
ENSG00000223496	EXOSC6	70	34.555	ENSMLEG00000041197	EXOSC4	72	34.392	Mandrillus_leucophaeus
ENSG00000223496	EXOSC6	72	34.184	ENSMAMG00000014749	exosc4	74	34.021	Mastacembelus_armatus
ENSG00000223496	EXOSC6	97	43.772	ENSMAMG00000016983	exosc6	95	44.364	Mastacembelus_armatus
ENSG00000223496	EXOSC6	97	42.908	ENSMZEG00005010720	exosc6	95	42.754	Maylandia_zebra
ENSG00000223496	EXOSC6	72	33.673	ENSMZEG00005025086	exosc4	74	33.505	Maylandia_zebra
ENSG00000223496	EXOSC6	96	94.231	ENSMAUG00000008040	Exosc6	96	94.231	Mesocricetus_auratus
ENSG00000223496	EXOSC6	70	34.555	ENSMAUG00000007911	Exosc4	72	34.392	Mesocricetus_auratus
ENSG00000223496	EXOSC6	100	96.324	ENSMICG00000027202	EXOSC6	100	96.324	Microcebus_murinus
ENSG00000223496	EXOSC6	96	93.846	ENSMOCG00000003020	Exosc6	96	93.846	Microtus_ochrogaster
ENSG00000223496	EXOSC6	70	34.555	ENSMOCG00000020295	Exosc4	72	34.392	Microtus_ochrogaster
ENSG00000223496	EXOSC6	72	33.673	ENSMMOG00000016779	exosc4	74	33.505	Mola_mola
ENSG00000223496	EXOSC6	94	35.766	ENSMMOG00000002581	exosc6	94	34.909	Mola_mola
ENSG00000223496	EXOSC6	70	35.079	ENSMODG00000010435	EXOSC4	82	34.921	Monodelphis_domestica
ENSG00000223496	EXOSC6	99	59.712	ENSMODG00000014523	EXOSC6	94	83.459	Monodelphis_domestica
ENSG00000223496	EXOSC6	97	40.426	ENSMALG00000007871	exosc6	91	41.304	Monopterus_albus
ENSG00000223496	EXOSC6	72	34.694	ENSMALG00000020564	exosc4	74	33.505	Monopterus_albus
ENSG00000223496	EXOSC6	70	34.555	MGP_CAROLIEiJ_G0019919	Exosc4	72	34.392	Mus_caroli
ENSG00000223496	EXOSC6	96	91.571	ENSMUSG00000109941	Exosc6	96	91.571	Mus_musculus
ENSG00000223496	EXOSC6	70	34.555	ENSMUSG00000034259	Exosc4	72	34.392	Mus_musculus
ENSG00000223496	EXOSC6	70	34.555	MGP_PahariEiJ_G0019929	Exosc4	72	34.392	Mus_pahari
ENSG00000223496	EXOSC6	70	34.555	MGP_SPRETEiJ_G0020822	Exosc4	72	34.392	Mus_spretus
ENSG00000223496	EXOSC6	55	32.667	ENSMPUG00000007260	EXOSC4	65	33.333	Mustela_putorius_furo
ENSG00000223496	EXOSC6	67	91.667	ENSMLUG00000023828	EXOSC6	93	92.958	Myotis_lucifugus
ENSG00000223496	EXOSC6	70	34.555	ENSNGAG00000022428	Exosc4	72	34.392	Nannospalax_galili
ENSG00000223496	EXOSC6	97	41.958	ENSNBRG00000007400	exosc6	95	42.391	Neolamprologus_brichardi
ENSG00000223496	EXOSC6	72	33.673	ENSNBRG00000012326	exosc4	74	33.505	Neolamprologus_brichardi
ENSG00000223496	EXOSC6	70	34.555	ENSNLEG00000010449	EXOSC4	72	34.392	Nomascus_leucogenys
ENSG00000223496	EXOSC6	70	35.079	ENSMEUG00000011002	EXOSC4	72	34.921	Notamacropus_eugenii
ENSG00000223496	EXOSC6	96	94.615	ENSODEG00000020448	EXOSC6	96	94.615	Octodon_degus
ENSG00000223496	EXOSC6	70	34.555	ENSODEG00000013951	EXOSC4	72	34.392	Octodon_degus
ENSG00000223496	EXOSC6	97	43.816	ENSONIG00000011184	exosc6	96	42.960	Oreochromis_niloticus
ENSG00000223496	EXOSC6	72	33.673	ENSONIG00000009617	exosc4	74	33.505	Oreochromis_niloticus
ENSG00000223496	EXOSC6	86	31.197	ENSOANG00000014904	EXOSC4	71	34.359	Ornithorhynchus_anatinus
ENSG00000223496	EXOSC6	70	34.555	ENSOCUG00000021243	EXOSC4	72	34.392	Oryctolagus_cuniculus
ENSG00000223496	EXOSC6	88	31.687	ENSORLG00000017295	exosc4	74	34.021	Oryzias_latipes
ENSG00000223496	EXOSC6	100	44.056	ENSORLG00000013325	exosc6	95	43.796	Oryzias_latipes
ENSG00000223496	EXOSC6	100	44.056	ENSORLG00020017597	exosc6	95	43.796	Oryzias_latipes_hni
ENSG00000223496	EXOSC6	88	31.687	ENSORLG00020009788	exosc4	74	34.021	Oryzias_latipes_hni
ENSG00000223496	EXOSC6	88	32.099	ENSORLG00015009754	exosc4	74	34.021	Oryzias_latipes_hsok
ENSG00000223496	EXOSC6	100	44.056	ENSORLG00015007795	exosc6	95	43.796	Oryzias_latipes_hsok
ENSG00000223496	EXOSC6	83	32.035	ENSOMEG00000005800	exosc4	74	34.021	Oryzias_melastigma
ENSG00000223496	EXOSC6	97	44.643	ENSOMEG00000014317	exosc6	96	43.796	Oryzias_melastigma
ENSG00000223496	EXOSC6	70	34.555	ENSOGAG00000007411	EXOSC4	72	34.392	Otolemur_garnettii
ENSG00000223496	EXOSC6	100	96.324	ENSOGAG00000034381	EXOSC6	100	96.324	Otolemur_garnettii
ENSG00000223496	EXOSC6	70	35.751	ENSOARG00000015188	EXOSC4	72	33.862	Ovis_aries
ENSG00000223496	EXOSC6	70	34.555	ENSPPAG00000035746	EXOSC4	72	34.392	Pan_paniscus
ENSG00000223496	EXOSC6	96	95.769	ENSPPRG00000021385	EXOSC6	96	95.769	Panthera_pardus
ENSG00000223496	EXOSC6	70	34.031	ENSPPRG00000019782	EXOSC4	72	33.862	Panthera_pardus
ENSG00000223496	EXOSC6	100	99.632	ENSPTRG00000008296	EXOSC6	100	99.632	Pan_troglodytes
ENSG00000223496	EXOSC6	70	34.555	ENSPTRG00000020677	EXOSC4	72	34.392	Pan_troglodytes
ENSG00000223496	EXOSC6	70	34.555	ENSPANG00000023276	EXOSC4	72	34.392	Papio_anubis
ENSG00000223496	EXOSC6	100	97.426	ENSPANG00000003331	EXOSC6	100	97.426	Papio_anubis
ENSG00000223496	EXOSC6	71	34.184	ENSPKIG00000018362	exosc4	74	33.505	Paramormyrops_kingsleyae
ENSG00000223496	EXOSC6	99	47.719	ENSPKIG00000022020	exosc6	96	49.455	Paramormyrops_kingsleyae
ENSG00000223496	EXOSC6	86	31.224	ENSPMGG00000019307	exosc4	90	31.330	Periophthalmus_magnuspinnatus
ENSG00000223496	EXOSC6	97	39.855	ENSPMGG00000016974	exosc6	95	39.852	Periophthalmus_magnuspinnatus
ENSG00000223496	EXOSC6	70	34.555	ENSPEMG00000017031	Exosc4	72	34.392	Peromyscus_maniculatus_bairdii
ENSG00000223496	EXOSC6	72	33.838	ENSPMAG00000001175	exosc4	74	31.959	Petromyzon_marinus
ENSG00000223496	EXOSC6	70	34.555	ENSPCIG00000009102	EXOSC4	72	34.392	Phascolarctos_cinereus
ENSG00000223496	EXOSC6	95	59.774	ENSPCIG00000006274	-	75	59.774	Phascolarctos_cinereus
ENSG00000223496	EXOSC6	98	77.737	ENSPCIG00000010685	EXOSC6	86	79.026	Phascolarctos_cinereus
ENSG00000223496	EXOSC6	83	31.602	ENSPFOG00000015214	exosc4	74	33.505	Poecilia_formosa
ENSG00000223496	EXOSC6	97	45.907	ENSPFOG00000015869	exosc6	95	45.652	Poecilia_formosa
ENSG00000223496	EXOSC6	83	31.602	ENSPLAG00000018751	exosc4	74	33.505	Poecilia_latipinna
ENSG00000223496	EXOSC6	97	45.552	ENSPLAG00000014150	exosc6	95	45.290	Poecilia_latipinna
ENSG00000223496	EXOSC6	97	45.907	ENSPMEG00000019665	exosc6	95	45.652	Poecilia_mexicana
ENSG00000223496	EXOSC6	83	31.602	ENSPMEG00000023116	exosc4	74	33.505	Poecilia_mexicana
ENSG00000223496	EXOSC6	97	44.840	ENSPREG00000019548	exosc6	95	44.565	Poecilia_reticulata
ENSG00000223496	EXOSC6	83	31.602	ENSPREG00000009632	exosc4	74	33.505	Poecilia_reticulata
ENSG00000223496	EXOSC6	100	98.897	ENSPPYG00000007545	EXOSC6	100	98.897	Pongo_abelii
ENSG00000223496	EXOSC6	70	33.508	ENSPPYG00000018959	EXOSC4	74	33.333	Pongo_abelii
ENSG00000223496	EXOSC6	70	34.555	ENSPCAG00000014920	EXOSC4	72	34.392	Procavia_capensis
ENSG00000223496	EXOSC6	99	92.989	ENSPCAG00000012874	EXOSC6	96	93.846	Procavia_capensis
ENSG00000223496	EXOSC6	62	34.706	ENSPCOG00000020992	EXOSC4	72	34.392	Propithecus_coquereli
ENSG00000223496	EXOSC6	70	34.031	ENSPVAG00000007100	EXOSC4	72	33.862	Pteropus_vampyrus
ENSG00000223496	EXOSC6	96	95.385	ENSPVAG00000000668	EXOSC6	96	95.385	Pteropus_vampyrus
ENSG00000223496	EXOSC6	97	42.657	ENSPNYG00000010784	exosc6	95	42.143	Pundamilia_nyererei
ENSG00000223496	EXOSC6	72	33.673	ENSPNYG00000014429	exosc4	74	33.505	Pundamilia_nyererei
ENSG00000223496	EXOSC6	98	44.484	ENSPNAG00000008453	exosc6	96	44.727	Pygocentrus_nattereri
ENSG00000223496	EXOSC6	96	92.308	ENSRNOG00000018582	Exosc6	96	92.308	Rattus_norvegicus
ENSG00000223496	EXOSC6	70	34.555	ENSRNOG00000012348	Exosc4	72	34.392	Rattus_norvegicus
ENSG00000223496	EXOSC6	100	88.235	ENSRBIG00000003409	EXOSC6	100	88.235	Rhinopithecus_bieti
ENSG00000223496	EXOSC6	70	34.555	ENSRBIG00000038476	EXOSC4	72	34.392	Rhinopithecus_bieti
ENSG00000223496	EXOSC6	70	34.555	ENSRROG00000038556	EXOSC4	72	34.392	Rhinopithecus_roxellana
ENSG00000223496	EXOSC6	70	35.079	ENSSHAG00000005397	EXOSC4	72	34.921	Sarcophilus_harrisii
ENSG00000223496	EXOSC6	99	59.286	ENSSHAG00000004175	EXOSC6	96	59.851	Sarcophilus_harrisii
ENSG00000223496	EXOSC6	72	32.143	ENSSFOG00015004133	exosc4	74	31.959	Scleropages_formosus
ENSG00000223496	EXOSC6	99	41.111	ENSSFOG00015011830	exosc6	93	40.076	Scleropages_formosus
ENSG00000223496	EXOSC6	97	41.844	ENSSMAG00000014550	exosc6	95	41.429	Scophthalmus_maximus
ENSG00000223496	EXOSC6	83	32.035	ENSSMAG00000020020	exosc4	74	33.505	Scophthalmus_maximus
ENSG00000223496	EXOSC6	97	43.571	ENSSDUG00000021109	exosc6	95	42.909	Seriola_dumerili
ENSG00000223496	EXOSC6	72	34.184	ENSSDUG00000018966	exosc4	74	34.021	Seriola_dumerili
ENSG00000223496	EXOSC6	100	43.299	ENSSLDG00000017776	exosc6	94	42.909	Seriola_lalandi_dorsalis
ENSG00000223496	EXOSC6	72	34.184	ENSSLDG00000008003	exosc4	74	34.021	Seriola_lalandi_dorsalis
ENSG00000223496	EXOSC6	61	31.138	ENSSPUG00000009644	EXOSC4	80	30.952	Sphenodon_punctatus
ENSG00000223496	EXOSC6	72	34.483	ENSSPAG00000016707	exosc4	69	34.328	Stegastes_partitus
ENSG00000223496	EXOSC6	97	43.617	ENSSPAG00000001379	exosc6	95	43.273	Stegastes_partitus
ENSG00000223496	EXOSC6	96	93.846	ENSSSCG00000002719	EXOSC6	96	93.846	Sus_scrofa
ENSG00000223496	EXOSC6	70	34.555	ENSSSCG00000005925	EXOSC4	72	34.392	Sus_scrofa
ENSG00000223496	EXOSC6	71	33.505	ENSTRUG00000025054	exosc4	74	33.505	Takifugu_rubripes
ENSG00000223496	EXOSC6	97	43.416	ENSTRUG00000023811	exosc6	82	43.636	Takifugu_rubripes
ENSG00000223496	EXOSC6	71	32.990	ENSTNIG00000008519	exosc4	74	32.990	Tetraodon_nigroviridis
ENSG00000223496	EXOSC6	100	46.154	ENSTNIG00000004018	exosc6	95	45.769	Tetraodon_nigroviridis
ENSG00000223496	EXOSC6	70	34.031	ENSUAMG00000020173	EXOSC4	72	33.862	Ursus_americanus
ENSG00000223496	EXOSC6	70	34.031	ENSVVUG00000009675	EXOSC4	72	33.862	Vulpes_vulpes
ENSG00000223496	EXOSC6	100	57.544	ENSXETG00000007667	exosc6	99	54.930	Xenopus_tropicalis
ENSG00000223496	EXOSC6	71	34.184	ENSXCOG00000015017	exosc4	74	33.505	Xiphophorus_couchianus
ENSG00000223496	EXOSC6	97	45.196	ENSXCOG00000013623	exosc6	95	44.928	Xiphophorus_couchianus
ENSG00000223496	EXOSC6	97	44.840	ENSXMAG00000006280	exosc6	95	44.565	Xiphophorus_maculatus
ENSG00000223496	EXOSC6	71	34.184	ENSXMAG00000016287	exosc4	74	33.505	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000176	nuclear exosome (RNase complex)	21873635.	IBA	Component
GO:0000177	cytoplasmic exosome (RNase complex)	21873635.	IBA	Component
GO:0000178	exosome (RNase complex)	20531389.	IDA	Component
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0004532	exoribonuclease activity	17174896.	IDA	Function
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006364	rRNA processing	-	TAS	Process
GO:0016075	rRNA catabolic process	21873635.	IBA	Process
GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'	21873635.	IBA	Process
GO:0034475	U4 snRNA 3'-end processing	21873635.	IBA	Process
GO:0043488	regulation of mRNA stability	-	TAS	Process
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	-	TAS	Process
GO:0045006	DNA deamination	21255825.	IDA	Process
GO:0045190	isotype switching	-	ISS	Process
GO:0045830	positive regulation of isotype switching	-	IEA	Process
GO:0071028	nuclear mRNA surveillance	21873635.	IBA	Process
GO:0071051	polyadenylation-dependent snoRNA 3'-end processing	21873635.	IBA	Process
GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	-	IEA	Process