EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000225921 (Gene tree)
Gene ID: 51406
Gene Symbol: NOL7
Alias: NOP27|RARG-1|dJ223E5.2|C6orf90|PQBP3
Full Name: nucleolar protein 7
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 17,413 bases
Position: chr6:13,615,327-13,632,739
Accession: 21040
RBP type: canonical RBP
Summary: The protein encoded by this gene localizes to the nucleolus, where it maintains nucleolar structure and cell growth rates. The encoded protein also functions as a tumor suppressor and regulator of angiogenesis. The RB tumor suppressor gene recruits transcription factors to this gene and positively regulates its expression. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000405674	NUC129	PF08157.11	1.6e-31	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000451315	NOL7-202	1184	-	ENSP00000405674	257 (aa)	-	Q9UMY1
ENST00000420088	NOL7-201	646	-	ENSP00000404836	83 (aa)	-	H7C2B1
ENST00000474485	NOL7-203	920	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000225921's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000225921's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000225921	NOL7	76	49.206	ENSAPOG00000024363	-	83	38.421	Acanthochromis_polyacanthus
ENSG00000225921	NOL7	82	51.471	ENSACIG00000003537	nol7	60	40.116	Amphilophus_citrinellus
ENSG00000225921	NOL7	64	37.805	ENSAPEG00000002647	nol7	76	39.877	Amphiprion_percula
ENSG00000225921	NOL7	75	50.000	ENSATEG00000013704	nol7	81	40.642	Anabas_testudineus
ENSG00000225921	NOL7	95	49.367	ENSACAG00000028554	NOL7	92	43.038	Anolis_carolinensis
ENSG00000225921	NOL7	100	97.276	ENSANAG00000035792	NOL7	100	97.276	Aotus_nancymaae
ENSG00000225921	NOL7	84	50.000	ENSACLG00000024521	nol7	83	39.891	Astatotilapia_calliptera
ENSG00000225921	NOL7	77	43.750	ENSAMXG00000014164	nol7	83	40.212	Astyanax_mexicanus
ENSG00000225921	NOL7	100	87.938	ENSBTAG00000021554	NOL7	99	87.938	Bos_taurus
ENSG00000225921	NOL7	100	97.276	ENSCJAG00000019798	NOL7	100	97.276	Callithrix_jacchus
ENSG00000225921	NOL7	100	82.576	ENSCAFG00000009846	NOL7	100	83.333	Canis_familiaris
ENSG00000225921	NOL7	100	83.650	ENSCAFG00020012980	NOL7	100	84.411	Canis_lupus_dingo
ENSG00000225921	NOL7	100	68.914	ENSCHIG00000020887	NOL7	99	69.173	Capra_hircus
ENSG00000225921	NOL7	100	89.105	ENSTSYG00000008153	NOL7	99	92.218	Carlito_syrichta
ENSG00000225921	NOL7	100	87.160	ENSCPOG00000011722	NOL7	99	87.160	Cavia_porcellus
ENSG00000225921	NOL7	100	96.887	ENSCCAG00000029996	NOL7	100	96.887	Cebus_capucinus
ENSG00000225921	NOL7	100	98.833	ENSCATG00000040146	NOL7	100	98.833	Cercocebus_atys
ENSG00000225921	NOL7	100	90.661	ENSCLAG00000003793	NOL7	99	90.661	Chinchilla_lanigera
ENSG00000225921	NOL7	100	97.276	ENSCSAG00000007535	NOL7	100	97.276	Chlorocebus_sabaeus
ENSG00000225921	NOL7	57	86.577	ENSCHOG00000006778	NOL7	99	86.577	Choloepus_hoffmanni
ENSG00000225921	NOL7	89	58.108	ENSCPBG00000016731	NOL7	90	53.425	Chrysemys_picta_bellii
ENSG00000225921	NOL7	100	97.665	ENSCANG00000032163	NOL7	100	97.665	Colobus_angolensis_palliatus
ENSG00000225921	NOL7	99	77.734	ENSCGRG00001013208	Nol7	99	77.734	Cricetulus_griseus_chok1gshd
ENSG00000225921	NOL7	99	77.734	ENSCGRG00000003296	Nol7	99	77.734	Cricetulus_griseus_crigri
ENSG00000225921	NOL7	73	49.180	ENSCVAG00000000768	nol7	78	39.362	Cyprinodon_variegatus
ENSG00000225921	NOL7	77	46.875	ENSDARG00000075795	nol7	70	39.785	Danio_rerio
ENSG00000225921	NOL7	93	93.506	ENSDNOG00000048157	NOL7	98	83.588	Dasypus_novemcinctus
ENSG00000225921	NOL7	100	71.705	ENSDORG00000005279	Nol7	100	71.318	Dipodomys_ordii
ENSG00000225921	NOL7	98	63.492	ENSETEG00000019178	NOL7	100	63.492	Echinops_telfairi
ENSG00000225921	NOL7	100	87.308	ENSEASG00005011840	NOL7	60	86.538	Equus_asinus_asinus
ENSG00000225921	NOL7	90	89.333	ENSEEUG00000007656	NOL7	98	79.681	Erinaceus_europaeus
ENSG00000225921	NOL7	75	51.613	ENSELUG00000017668	nol7	82	39.691	Esox_lucius
ENSG00000225921	NOL7	100	87.645	ENSFCAG00000032610	NOL7	99	88.803	Felis_catus
ENSG00000225921	NOL7	92	94.737	ENSFDAG00000012580	NOL7	100	74.803	Fukomys_damarensis
ENSG00000225921	NOL7	75	46.774	ENSFHEG00000004742	nol7	86	37.368	Fundulus_heteroclitus
ENSG00000225921	NOL7	75	58.065	ENSGALG00000012695	NOL7	86	46.429	Gallus_gallus
ENSG00000225921	NOL7	73	49.180	ENSGAFG00000018586	nol7	76	40.426	Gambusia_affinis
ENSG00000225921	NOL7	77	53.125	ENSGACG00000017989	nol7	86	40.314	Gasterosteus_aculeatus
ENSG00000225921	NOL7	88	53.425	ENSGAGG00000000863	NOL7	82	52.083	Gopherus_agassizii
ENSG00000225921	NOL7	100	99.611	ENSGGOG00000007677	NOL7	100	99.611	Gorilla_gorilla
ENSG00000225921	NOL7	84	48.571	ENSHBUG00000001172	nol7	81	39.791	Haplochromis_burtoni
ENSG00000225921	NOL7	98	89.020	ENSHGLG00000004243	NOL7	98	89.412	Heterocephalus_glaber_female
ENSG00000225921	NOL7	94	89.744	ENSHGLG00100004697	NOL7	99	88.372	Heterocephalus_glaber_male
ENSG00000225921	NOL7	78	47.692	ENSHCOG00000011325	nol7	83	37.696	Hippocampus_comes
ENSG00000225921	NOL7	78	46.154	ENSIPUG00000003294	nol7	83	40.107	Ictalurus_punctatus
ENSG00000225921	NOL7	100	87.549	ENSSTOG00000008274	NOL7	99	86.770	Ictidomys_tridecemlineatus
ENSG00000225921	NOL7	99	79.688	ENSJJAG00000000524	Nol7	98	79.297	Jaculus_jaculus
ENSG00000225921	NOL7	71	55.932	ENSKMAG00000000564	nol7	80	39.037	Kryptolebias_marmoratus
ENSG00000225921	NOL7	75	51.613	ENSLBEG00000022992	-	57	38.889	Labrus_bergylta
ENSG00000225921	NOL7	83	52.174	ENSLACG00000006749	NOL7	77	45.596	Latimeria_chalumnae
ENSG00000225921	NOL7	90	50.667	ENSLOCG00000011505	nol7	80	40.722	Lepisosteus_oculatus
ENSG00000225921	NOL7	99	90.551	ENSLAFG00000010434	NOL7	98	90.551	Loxodonta_africana
ENSG00000225921	NOL7	100	98.062	ENSMFAG00000017762	NOL7	100	98.062	Macaca_fascicularis
ENSG00000225921	NOL7	93	97.925	ENSMMUG00000008681	NOL7	100	97.925	Macaca_mulatta
ENSG00000225921	NOL7	100	98.444	ENSMNEG00000034369	NOL7	100	98.444	Macaca_nemestrina
ENSG00000225921	NOL7	100	98.833	ENSMLEG00000030932	NOL7	100	98.833	Mandrillus_leucophaeus
ENSG00000225921	NOL7	73	52.459	ENSMAMG00000014577	nol7	81	39.572	Mastacembelus_armatus
ENSG00000225921	NOL7	84	50.000	ENSMZEG00005003849	nol7	81	40.314	Maylandia_zebra
ENSG00000225921	NOL7	99	74.708	ENSMAUG00000005811	Nol7	99	75.486	Mesocricetus_auratus
ENSG00000225921	NOL7	100	91.440	ENSMICG00000044935	NOL7	99	91.440	Microcebus_murinus
ENSG00000225921	NOL7	95	77.459	ENSMOCG00000015174	Nol7	99	77.734	Microtus_ochrogaster
ENSG00000225921	NOL7	89	72.973	ENSMODG00000010641	NOL7	96	54.054	Monodelphis_domestica
ENSG00000225921	NOL7	73	49.180	ENSMALG00000019218	nol7	81	40.426	Monopterus_albus
ENSG00000225921	NOL7	90	84.000	MGP_CAROLIEiJ_G0018469	Nol7	99	76.172	Mus_caroli
ENSG00000225921	NOL7	95	76.639	ENSMUSG00000063200	Nol7	99	76.172	Mus_musculus
ENSG00000225921	NOL7	97	77.912	MGP_PahariEiJ_G0019537	Nol7	99	76.953	Mus_pahari
ENSG00000225921	NOL7	95	76.639	MGP_SPRETEiJ_G0019348	Nol7	99	76.172	Mus_spretus
ENSG00000225921	NOL7	100	82.759	ENSMPUG00000000692	NOL7	100	84.674	Mustela_putorius_furo
ENSG00000225921	NOL7	100	86.973	ENSMLUG00000014627	NOL7	99	86.973	Myotis_lucifugus
ENSG00000225921	NOL7	99	78.516	ENSNGAG00000023369	Nol7	99	77.734	Nannospalax_galili
ENSG00000225921	NOL7	55	54.348	ENSNBRG00000000897	nol7	76	30.481	Neolamprologus_brichardi
ENSG00000225921	NOL7	100	98.833	ENSNLEG00000000883	NOL7	100	98.833	Nomascus_leucogenys
ENSG00000225921	NOL7	100	89.105	ENSODEG00000005771	NOL7	99	89.105	Octodon_degus
ENSG00000225921	NOL7	71	54.237	ENSONIG00000001469	nol7	95	40.816	Oreochromis_niloticus
ENSG00000225921	NOL7	99	52.439	ENSOANG00000019878	-	90	46.078	Ornithorhynchus_anatinus
ENSG00000225921	NOL7	64	80.606	ENSOCUG00000007251	NOL7	99	80.606	Oryctolagus_cuniculus
ENSG00000225921	NOL7	82	48.529	ENSORLG00000006271	nol7	75	39.153	Oryzias_latipes
ENSG00000225921	NOL7	82	48.529	ENSORLG00020020343	nol7	78	39.153	Oryzias_latipes_hni
ENSG00000225921	NOL7	82	48.529	ENSORLG00015019857	nol7	75	39.683	Oryzias_latipes_hsok
ENSG00000225921	NOL7	87	47.222	ENSOMEG00000020030	nol7	75	40.107	Oryzias_melastigma
ENSG00000225921	NOL7	99	92.549	ENSOGAG00000013445	NOL7	99	92.549	Otolemur_garnettii
ENSG00000225921	NOL7	100	87.160	ENSOARG00000013334	NOL7	84	87.160	Ovis_aries
ENSG00000225921	NOL7	100	100.000	ENSPPAG00000028545	NOL7	100	100.000	Pan_paniscus
ENSG00000225921	NOL7	100	71.042	ENSPPRG00000002215	NOL7	99	72.973	Panthera_pardus
ENSG00000225921	NOL7	65	89.286	ENSPTIG00000006154	NOL7	65	89.286	Panthera_tigris_altaica
ENSG00000225921	NOL7	100	100.000	ENSPTRG00000017737	NOL7	100	100.000	Pan_troglodytes
ENSG00000225921	NOL7	100	99.222	ENSPTRG00000049899	-	100	99.222	Pan_troglodytes
ENSG00000225921	NOL7	100	98.833	ENSPANG00000025187	NOL7	100	98.833	Papio_anubis
ENSG00000225921	NOL7	82	50.000	ENSPKIG00000008152	nol7	83	39.901	Paramormyrops_kingsleyae
ENSG00000225921	NOL7	63	57.692	ENSPSIG00000009804	NOL7	77	51.807	Pelodiscus_sinensis
ENSG00000225921	NOL7	61	50.980	ENSPMGG00000016546	nol7	64	35.465	Periophthalmus_magnuspinnatus
ENSG00000225921	NOL7	99	80.469	ENSPEMG00000013753	Nol7	99	80.469	Peromyscus_maniculatus_bairdii
ENSG00000225921	NOL7	98	40.741	ENSPFOG00000000700	nol7	79	39.572	Poecilia_formosa
ENSG00000225921	NOL7	73	49.180	ENSPLAG00000009132	nol7	76	41.489	Poecilia_latipinna
ENSG00000225921	NOL7	55	52.174	ENSPREG00000020471	nol7	57	31.395	Poecilia_reticulata
ENSG00000225921	NOL7	100	99.222	ENSPPYG00000016243	NOL7	100	99.222	Pongo_abelii
ENSG00000225921	NOL7	98	84.980	ENSPCAG00000001391	NOL7	98	84.980	Procavia_capensis
ENSG00000225921	NOL7	100	91.829	ENSPCOG00000019187	NOL7	99	91.829	Propithecus_coquereli
ENSG00000225921	NOL7	100	79.070	ENSPVAG00000006109	NOL7	99	79.070	Pteropus_vampyrus
ENSG00000225921	NOL7	55	52.174	ENSPNYG00000019707	nol7	61	34.884	Pundamilia_nyererei
ENSG00000225921	NOL7	76	35.025	ENSPNAG00000025956	nol7	62	34.940	Pygocentrus_nattereri
ENSG00000225921	NOL7	98	75.294	ENSRNOG00000017904	Nol7	84	78.039	Rattus_norvegicus
ENSG00000225921	NOL7	100	83.268	ENSRBIG00000030164	NOL7	100	80.309	Rhinopithecus_bieti
ENSG00000225921	NOL7	100	98.833	ENSRROG00000026044	NOL7	100	98.833	Rhinopithecus_roxellana
ENSG00000225921	NOL7	100	95.720	ENSSBOG00000020450	NOL7	100	95.720	Saimiri_boliviensis_boliviensis
ENSG00000225921	NOL7	94	41.026	ENSSFOG00015020387	nol7	82	44.103	Scleropages_formosus
ENSG00000225921	NOL7	76	50.794	ENSSMAG00000005027	nol7	67	38.624	Scophthalmus_maximus
ENSG00000225921	NOL7	84	54.286	ENSSDUG00000005398	nol7	81	42.857	Seriola_dumerili
ENSG00000225921	NOL7	82	55.882	ENSSLDG00000000916	nol7	80	40.449	Seriola_lalandi_dorsalis
ENSG00000225921	NOL7	80	65.152	ENSSPUG00000009958	NOL7	87	49.479	Sphenodon_punctatus
ENSG00000225921	NOL7	76	49.206	ENSSPAG00000015775	nol7	83	41.714	Stegastes_partitus
ENSG00000225921	NOL7	100	86.770	ENSSSCG00000040816	NOL7	99	85.992	Sus_scrofa
ENSG00000225921	NOL7	73	52.459	ENSTNIG00000007997	nol7	82	40.741	Tetraodon_nigroviridis
ENSG00000225921	NOL7	65	87.500	ENSTBEG00000015755	NOL7	99	87.500	Tupaia_belangeri
ENSG00000225921	NOL7	100	76.834	ENSTTRG00000007796	NOL7	99	76.834	Tursiops_truncatus
ENSG00000225921	NOL7	100	85.441	ENSUAMG00000014386	NOL7	99	86.590	Ursus_americanus
ENSG00000225921	NOL7	66	85.380	ENSUMAG00000017888	NOL7	78	85.294	Ursus_maritimus
ENSG00000225921	NOL7	58	81.579	ENSVVUG00000003816	-	96	81.579	Vulpes_vulpes
ENSG00000225921	NOL7	76	33.498	ENSXCOG00000019968	nol7	69	33.721	Xiphophorus_couchianus
ENSG00000225921	NOL7	73	49.180	ENSXMAG00000020878	nol7	76	40.426	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.	HDA	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0005739	mitochondrion	-	IDA	Component