EuRBPDB

Description

Ensembl ID: ENSG00000226784 (Gene tree)
Gene ID: 441531
Gene Symbol: PGAM4
Alias: dJ1000K24.1|PGAM3|PGAM-B|PGAM1
Full Name: phosphoglycerate mutase family member 4
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 1,678 bases
Position: chrX:77,967,961-77,969,638
Accession: 21731
RBP type: non-canonical RBP
Summary: This intronless gene appears to have arisen from a retrotransposition event, yet it is thought to be an expressed, protein-coding gene. The encoded protein is a member of the phosphoglycerate mutase family, a set of enzymes that catalyze the transfer of a phosphate group from 3-phosphoglycerate to 2-phosphoglycerate. [provided by RefSeq, May 2010]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000458128	PGAM4-201	765	-	ENSP00000412189	254 (aa)	-	Q8N0Y7

Gene Model

Pathways

Pathway ID	Pathway Name	Source
hsa00010	Glycolysis / Gluconeogenesis	KEGG
hsa00260	Glycine, serine and threonine metabolism	KEGG
hsa01100	Metabolic pathways	KEGG
hsa01200	Carbon metabolism	KEGG
hsa01230	Biosynthesis of amino acids	KEGG
hsa04922	Glucagon signaling pathway	KEGG
hsa05230	Central carbon metabolism in cancer	KEGG

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000226784	PGAM4	98	66.534	FBgn0014869	Pglym78	98	66.534	Drosophila_melanogaster
ENSG00000226784	PGAM4	97	48.583	YKL152C		99	48.583	Saccharomyces_cerevisiae

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0004082	bisphosphoglycerate mutase activity	-	IEA	Function
GO:0004619	phosphoglycerate mutase activity	22590500.	IMP	Function
GO:0004619	phosphoglycerate mutase activity	11961099.	NAS	Function
GO:0006096	glycolytic process	22590500.	IMP	Process
GO:0006096	glycolytic process	11961099.	NAS	Process
GO:0016787	hydrolase activity	-	IEA	Function
GO:0070062	extracellular exosome	23533145.	HDA	Component
GO:0097228	sperm principal piece	22590500.	IDA	Component
GO:1902093	positive regulation of flagellated sperm motility	22590500.	NAS	Process