EuRBPDB

Ensembl ID

ENSG00000228049 (Gene tree)

Gene ID

246721

Gene Symbol

POLR2J2

Alias

RPB11b1

Full Name

RNA polymerase II subunit J2

Gene Type

protein_coding

Species

Homo_sapiens

Status

confidence

Strand

Minus strand

Length

34,982 bases

Position

chr7:102,636,748-102,671,729

Accession

23208

RBP type

canonical RBP

Summary

This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo. [provided by RefSeq, Jul 2008]