EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000240563 (Gene tree)
Gene ID: 54596
Gene Symbol: L1TD1
Alias: FLJ10884|ECAT11
Full Name: LINE1 type transposase domain containing 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 17,527 bases
Position: chr1:62,194,802-62,212,328
Accession: 25595
RBP type: canonical RBP
Summary: (LINE1 Type Transposase Domain Containing 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and obsolete signal transducer activity.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000419901	Transposase_22	PF02994.14	2.3e-24	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
22162396	RNA-binding protein L1TD1 interacts with LIN28 via RNA and is required for human embryonic stem cell self-renewal and cancer cell proliferation.	Stem Cells	2012 Mar	Narva E	doi: 10.1002/stem.1013.
25702638	The L1TD1 protein interactome reveals the importance of post-transcriptional regulation in human pluripotency.	Stem Cell Reports	2015 Mar 10	Emani MR	doi: 10.1016/j.stemcr.2015.01.014

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000498273	L1TD1-201	3849	-	ENSP00000419901	865 (aa)	-	Q5T7N2

Gene Model

Click here to download ENSG00000240563's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000240563	Bone Density	9E-6	28181694

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000240563	rs6656763	1	62196120	G	Lip morphology	29921221	[NR] unit decrease	0.017	EFO_0007845
ENSG00000240563	rs7542665	1	62207365	C	Colorectal cancer	30529582	[1.05-1.11]	1.08	EFO_0005842

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000240563's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000240563	L1TD1	99	62.572	ENSAMEG00000014821	L1TD1	99	62.442	Ailuropoda_melanoleuca
ENSG00000240563	L1TD1	78	85.921	ENSCJAG00000038509	L1TD1	95	87.361	Callithrix_jacchus
ENSG00000240563	L1TD1	54	51.200	ENSCAFG00020012951	L1TD1	58	51.005	Canis_lupus_dingo
ENSG00000240563	L1TD1	100	87.313	ENSCATG00000038295	L1TD1	99	89.286	Cercocebus_atys
ENSG00000240563	L1TD1	100	86.736	ENSCSAG00000001337	L1TD1	99	87.185	Chlorocebus_sabaeus
ENSG00000240563	L1TD1	100	88.249	ENSCANG00000042261	L1TD1	99	88.594	Colobus_angolensis_palliatus
ENSG00000240563	L1TD1	99	47.680	ENSCGRG00001024238	L1td1	99	47.197	Cricetulus_griseus_chok1gshd
ENSG00000240563	L1TD1	99	47.680	ENSCGRG00000011853	L1td1	99	47.197	Cricetulus_griseus_crigri
ENSG00000240563	L1TD1	99	54.943	ENSDNOG00000039645	-	100	54.891	Dasypus_novemcinctus
ENSG00000240563	L1TD1	99	51.185	ENSDNOG00000040097	-	100	51.659	Dasypus_novemcinctus
ENSG00000240563	L1TD1	99	58.392	ENSEASG00005008811	L1TD1	63	65.426	Equus_asinus_asinus
ENSG00000240563	L1TD1	50	37.500	ENSECAG00000028123	-	65	40.249	Equus_caballus
ENSG00000240563	L1TD1	99	55.923	ENSECAG00000013248	L1TD1	80	64.066	Equus_caballus
ENSG00000240563	L1TD1	99	61.601	ENSFCAG00000042658	L1TD1	99	60.343	Felis_catus
ENSG00000240563	L1TD1	100	97.347	ENSGGOG00000026365	L1TD1	100	97.347	Gorilla_gorilla
ENSG00000240563	L1TD1	100	87.082	ENSMFAG00000031887	L1TD1	99	88.825	Macaca_fascicularis
ENSG00000240563	L1TD1	100	88.594	ENSMNEG00000030098	L1TD1	99	88.594	Macaca_nemestrina
ENSG00000240563	L1TD1	100	89.516	ENSMLEG00000039743	L1TD1	99	89.516	Mandrillus_leucophaeus
ENSG00000240563	L1TD1	63	53.950	ENSMAUG00000020769	L1td1	60	56.349	Mesocricetus_auratus
ENSG00000240563	L1TD1	99	68.023	ENSMICG00000045847	L1TD1	99	67.049	Microcebus_murinus
ENSG00000240563	L1TD1	51	54.299	ENSMOCG00000007037	L1td1	56	57.500	Microtus_ochrogaster
ENSG00000240563	L1TD1	60	51.064	MGP_CAROLIEiJ_G0026185	L1td1	54	54.444	Mus_caroli
ENSG00000240563	L1TD1	60	51.179	ENSMUSG00000087166	L1td1	59	52.800	Mus_musculus
ENSG00000240563	L1TD1	60	49.531	MGP_PahariEiJ_G0028522	L1td1	54	52.394	Mus_pahari
ENSG00000240563	L1TD1	60	50.708	MGP_SPRETEiJ_G0027153	L1td1	59	52.800	Mus_spretus
ENSG00000240563	L1TD1	88	50.852	ENSNGAG00000000776	L1td1	94	50.526	Nannospalax_galili
ENSG00000240563	L1TD1	100	92.857	ENSNLEG00000014904	L1TD1	99	92.742	Nomascus_leucogenys
ENSG00000240563	L1TD1	100	97.575	ENSPPAG00000043606	L1TD1	100	97.575	Pan_paniscus
ENSG00000240563	L1TD1	99	61.547	ENSPPRG00000011113	L1TD1	99	61.618	Panthera_pardus
ENSG00000240563	L1TD1	100	97.806	ENSPTRG00000034387	L1TD1	100	97.806	Pan_troglodytes
ENSG00000240563	L1TD1	100	87.082	ENSPANG00000021627	L1TD1	99	87.872	Papio_anubis
ENSG00000240563	L1TD1	99	45.244	ENSPEMG00000008068	L1td1	99	46.599	Peromyscus_maniculatus_bairdii
ENSG00000240563	L1TD1	100	91.109	ENSPPYG00000001286	L1TD1	99	91.109	Pongo_abelii
ENSG00000240563	L1TD1	99	68.894	ENSPCOG00000005879	L1TD1	99	70.298	Propithecus_coquereli
ENSG00000240563	L1TD1	100	87.529	ENSRBIG00000005782	L1TD1	99	87.774	Rhinopithecus_bieti
ENSG00000240563	L1TD1	100	87.659	ENSRROG00000042567	L1TD1	99	88.005	Rhinopithecus_roxellana
ENSG00000240563	L1TD1	78	63.696	ENSTBEG00000015274	L1TD1	99	48.092	Tupaia_belangeri
ENSG00000240563	L1TD1	99	62.121	ENSUAMG00000002306	L1TD1	99	60.950	Ursus_americanus
ENSG00000240563	L1TD1	99	57.293	ENSUMAG00000014924	L1TD1	99	58.460	Ursus_maritimus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003727	single-stranded RNA binding	21873635.	IBA	Function
GO:0032197	transposition, RNA-mediated	21873635.	IBA	Process
GO:1990904	ribonucleoprotein complex	21873635.	IBA	Component

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
28093071	SPAG6 and L1TD1 are transcriptionally regulated by DNA methylation in non-small cell lung cancers.	Mol Cancer	2017 Jan 5	Altenberger C	doi: 10.1186/s12943-016-0568-5.
21445976	LINE-1 hypomethylation is associated with bladder cancer risk among nonsmoking Chinese.	Int J Cancer	2012 Mar 1	Cash HL	doi: 10.1002/ijc.26098
23179365	LINE-1 hypomethylation in gastric cancer, detected by bisulfite pyrosequencing, is associated with poor prognosis.	Gastric Cancer	2013 Oct	Shigaki H	doi: 10.1007/s10120-012-0209-7

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr1	62209919	Missense_Mutation	novel	S382F	0.08
BLCA	chr1	62211442	3'UTR	rs535661631		0.08
BLCA	chr1	62210080	Missense_Mutation	novel	E436Q	0.14
BLCA	chr1	62211342	Missense_Mutation	novel	L856F	0.41
BLCA	chr1	62209942	Missense_Mutation	novel	E390K	0.1
BLCA	chr1	62211377	3'UTR	rs770777715		0.26
BRCA	chr1	62210152	Missense_Mutation	novel	I460L	0.49
BRCA	chr1	62206648	Missense_Mutation	NA	S7I	0.44
BRCA	chr1	62207540	Silent	NA	S304S	0.2
BRCA	chr1	62211118	Nonsense_Mutation	NA	E782*	0.21	Transposase_22
BRCA	chr1	62206804	Missense_Mutation	NA	M59K	0.18
CESC	chr1	62206986	Missense_Mutation	novel	E120K	0.19
CESC	chr1	62206639	Missense_Mutation	novel	V4A	0.42
CESC	chr1	62210941	Nonsense_Mutation	NA	E723*	0.4	Transposase_22
CESC	chr1	62210456	Missense_Mutation	novel	S561L	0.19
CESC	chr1	62209887	Missense_Mutation	novel	M371I	0.28
CESC	chr1	62206873	Missense_Mutation	NA	G82A	0.33
CHOL	chr1	62207184	Nonsense_Mutation	novel	G186*	0.07
COAD	chr1	62206910	Missense_Mutation	NA	E94D	0.42
COAD	chr1	62207133	Missense_Mutation	rs751577233	E169K	0.06
COAD	chr1	62207274	Missense_Mutation	novel	K216Q	0.1
COAD	chr1	62210483	Missense_Mutation	novel	K570T	0.34
COAD	chr1	62210848	Missense_Mutation	novel	D692N	0.29
COAD	chr1	62207078	Silent	NA	N150N	0.1
COAD	chr1	62210627	Missense_Mutation	novel	R618I	0.05
COAD	chr1	62211442	3'UTR	rs535661631		0.42
COAD	chr1	62210019	Silent	NA	E415E	0.05
COAD	chr1	62210649	Silent	novel	I625I	0.1
COAD	chr1	62206884	Missense_Mutation	NA	T86A	0.41
COAD	chr1	62211380	3'UTR	novel		0.27
COAD	chr1	62210374	Missense_Mutation	rs146015306	E534K	0.4
COAD	chr1	62211546	3'UTR	novel		0.29
COAD	chr1	62210120	Missense_Mutation	novel	H449R	0.09
COAD	chr1	62206884	Missense_Mutation	NA	T86A	0.1
COAD	chr1	62206613	5'UTR	novel		0.43
COAD	chr1	62210822	Frame_Shift_Del	novel	*Q683Hfs3**	0.25
COAD	chr1	62206622	5'UTR	novel		0.1
COAD	chr1	62207527	Missense_Mutation	NA	R300I	0.17
COAD	chr1	62207326	In_Frame_Del	novel	K234del	0.05
COAD	chr1	62210285	Missense_Mutation	rs534791481	R504H	0.22
COAD	chr1	62207439	Missense_Mutation	NA	D271Y	0.09
COAD	chr1	62206687	Missense_Mutation	novel	E20G	0.29
COAD	chr1	62210324	Missense_Mutation	NA	D517G	0.29
COAD	chr1	62207133	Missense_Mutation	rs751577233	E169K	0.19
COAD	chr1	62211040	Missense_Mutation	novel	T756A	0.2	Transposase_22
COAD	chr1	62207079	Nonsense_Mutation	rs771642989	E151*	0.36
ESCA	chr1	62211520	3'UTR	novel		0.75
GBM	chr1	62211441	3'UTR	rs574718447		0.37
GBM	chr1	62209921	Missense_Mutation	rs778590430	E383K	0.4
GBM	chr1	62211316	Missense_Mutation	novel	D848Y	0.29
HNSC	chr1	62211545	3'UTR	novel		0.4
HNSC	chr1	62211497	3'UTR	novel		0.23
HNSC	chr1	62206978	Missense_Mutation	novel	G117E	0.19
KIRC	chr1	62207456	Missense_Mutation	NA	F276L	0.2
KIRP	chr1	62207007	Missense_Mutation	NA	G127R	0.45
LGG	chr1	62211410	3'UTR	novel		0.25
LGG	chr1	62210475	Silent	novel	D567D	0.28
LGG	chr1	62210372	Missense_Mutation	novel	Q533L	0.22
LIHC	chr1	62210702	Missense_Mutation	NA	L643S	0.3
LIHC	chr1	62210506	Missense_Mutation	novel	S578C	0.33
LUAD	chr1	62210053	Missense_Mutation	NA	D427Y	0.24
LUAD	chr1	62206972	Missense_Mutation	novel	M115K	0.12
LUAD	chr1	62206924	Frame_Shift_Del	novel	*R99Nfs26**	0.25
LUAD	chr1	62210284	Missense_Mutation	novel	R504S	0.12
LUAD	chr1	62211203	Missense_Mutation	NA	V810D	0.31
LUAD	chr1	62210284	Missense_Mutation	rs139433745	R504C	0.18
LUAD	chr1	62211421	3'UTR	rs79364597		0.08
LUAD	chr1	62211421	3'UTR	novel		0.05
LUSC	chr1	62210065	Missense_Mutation	novel	G431W	0.27
LUSC	chr1	62210066	Missense_Mutation	NA	G431V	0.25
LUSC	chr1	62209848	Silent	NA	L358L	0.16
LUSC	chr1	62206990	Missense_Mutation	NA	G121E	0.18
LUSC	chr1	62209841	Missense_Mutation	novel	S356T	0.38
LUSC	chr1	62206977	Missense_Mutation	NA	G117W	0.39
LUSC	chr1	62210466	Missense_Mutation	novel	M564I	0.19
LUSC	chr1	62211469	3'UTR	novel		0.25
OV	chr1	62210185	In_Frame_Del	NA	D471_V473del	0.42
OV	chr1	62210911	Missense_Mutation	NA	Y713D	0.71	Transposase_22
OV	chr1	62211320	Missense_Mutation	NA	Y849C	0.43
OV	chr1	62210507	Missense_Mutation	novel	S578I	0.16
OV	chr1	62210096	Missense_Mutation	NA	E441G	0.27
OV	chr1	62206932	Frame_Shift_Del	NA	*Q103Sfs3**	0.23
PRAD	chr1	62206958	Silent	novel	L110L	0.32
READ	chr1	62210821	Missense_Mutation	NA	Q683E	0.33
READ	chr1	62206733	Missense_Mutation	novel	K35N	0.33
READ	chr1	62210788	Nonsense_Mutation	novel	E672*	0.58
READ	chr1	62206576	5'UTR	novel		0.37
READ	chr1	62207071	Missense_Mutation	NA	N148T	0.13
SARC	chr1	62206827	Missense_Mutation	novel	E67K	0.53
SARC	chr1	62206970	Silent	novel	G114G	0.56
SARC	chr1	62207175	Missense_Mutation	novel	D183N	0.55
SARC	chr1	62210316	Silent	rs747279476	L514L	0.53
SARC	chr1	62207178	Missense_Mutation	novel	R184G	0.1
SKCM	chr1	62210071	Missense_Mutation	NA	E433K	0.39
SKCM	chr1	62211461	3'UTR	novel		0.52
SKCM	chr1	62210017	Missense_Mutation	NA	E415K	0.62
SKCM	chr1	62210052	Silent	novel	E426E	0.17
SKCM	chr1	62207110	Missense_Mutation	NA	P161L	0.26
SKCM	chr1	62211442	3'UTR	rs535661631		0.34
SKCM	chr1	62206979	Silent	NA	G117G	0.21
SKCM	chr1	62209921	Missense_Mutation	rs778590430	E383K	0.43
SKCM	chr1	62210558	Missense_Mutation	novel	R595K	0.44
SKCM	chr1	62206806	Missense_Mutation	novel	E60K	0.25
SKCM	chr1	62210430	Silent	NA	T552T	0.54
SKCM	chr1	62206969	Missense_Mutation	NA	G114E	0.23
SKCM	chr1	62209990	Missense_Mutation	NA	E406K	0.27
SKCM	chr1	62210447	Missense_Mutation	rs776310502	P558L	0.29
SKCM	chr1	62211459	3'UTR	novel		0.29
SKCM	chr1	62206969	Missense_Mutation	NA	G114E	0.5
SKCM	chr1	62210308	Missense_Mutation	NA	S512G	0.16
SKCM	chr1	62211346	Missense_Mutation	novel	E858K	0.47
SKCM	chr1	62210243	Missense_Mutation	novel	G490E	0.23
SKCM	chr1	62206915	Missense_Mutation	NA	S96F	0.43
SKCM	chr1	62207019	Missense_Mutation	novel	E131K	0.31
SKCM	chr1	62210197	Missense_Mutation	novel	D475N	0.23
SKCM	chr1	62206839	Missense_Mutation	NA	E71K	0.67
SKCM	chr1	62207079	Missense_Mutation	NA	E151K	0.63
SKCM	chr1	62207079	Missense_Mutation	NA	E151K	0.56
SKCM	chr1	62210209	Missense_Mutation	rs754363697	E479K	0.96
SKCM	chr1	62210043	Silent	NA	G423G	0.34
SKCM	chr1	62210296	Missense_Mutation	NA	E508K	0.28
SKCM	chr1	62206946	Silent	NA	I106I	0.75
SKCM	chr1	62209783	Missense_Mutation	NA	D337N	0.21
SKCM	chr1	62206876	Missense_Mutation	NA	G83E	0.34
SKCM	chr1	62210545	Missense_Mutation	NA	E591K	0.24
SKCM	chr1	62209845	Silent	NA	F357F	0.48
SKCM	chr1	62206839	Missense_Mutation	NA	E71K	0.25
SKCM	chr1	62210215	Missense_Mutation	NA	E481K	0.28
SKCM	chr1	62210020	Missense_Mutation	NA	E416K	0.59
SKCM	chr1	62210487	Silent	rs758340016	K571K	0.3
SKCM	chr1	62209881	Silent	NA	E369E	0.44
SKCM	chr1	62207013	Missense_Mutation	NA	D129N	0.15
SKCM	chr1	62210302	Missense_Mutation	rs752701856	P510S	0.11
SKCM	chr1	62209845	Silent	NA	F357F	0.28
SKCM	chr1	62210397	Silent	NA	P541P	0.29
SKCM	chr1	62210225	Missense_Mutation	NA	G484E	0.38
SKCM	chr1	62211354	Silent	NA	L860L	0.29
SKCM	chr1	62206979	Silent	NA	G117G	0.17
SKCM	chr1	62210377	Missense_Mutation	rs765706497	E535K	0.4
SKCM	chr1	62209987	Missense_Mutation	NA	E405K	0.45
SKCM	chr1	62210369	Missense_Mutation	novel	T532I	0.26
STAD	chr1	62210186	Missense_Mutation	NA	D471V	0.12
STAD	chr1	62210362	Missense_Mutation	NA	H530Y	0.19
STAD	chr1	62211547	3'UTR	novel		0.26
STAD	chr1	62210472	Silent	rs540884928	H566H	0.1
STAD	chr1	62206959	Frame_Shift_Ins	rs753466100	*T113Nfs13**	0.13
STAD	chr1	62211547	3'UTR	novel		0.4
UCEC	chr1	62206891	Missense_Mutation	NA	P88H	0.37
UCEC	chr1	62211118	Nonsense_Mutation	NA	E782*	0.33	Transposase_22
UCEC	chr1	62206726	Missense_Mutation	NA	T33I	0.24
UCEC	chr1	62210478	Silent	novel	E568E	0.29
UCEC	chr1	62211426	3'UTR	novel		0.29
UCEC	chr1	62207272	Missense_Mutation	NA	R215I	0.59
UCEC	chr1	62209974	Silent	NA	T400T	0.36
UCEC	chr1	62210793	Missense_Mutation	NA	F673L	0.45
UCEC	chr1	62210986	Missense_Mutation	rs112463438	L738I	0.41	Transposase_22
UCEC	chr1	62211307	Nonsense_Mutation	NA	E845*	0.39
UCEC	chr1	62207269	Missense_Mutation	novel	E214V	0.4
UCEC	chr1	62210408	Missense_Mutation	novel	G545E	0.47
UCEC	chr1	62206910	Missense_Mutation	NA	E94D	0.48
UCEC	chr1	62210844	Silent	novel	Q690Q	0.72
UCEC	chr1	62206697	Silent	novel	T23T	0.38
UCEC	chr1	62206929	Nonsense_Mutation	novel	E101*	0.46
UCEC	chr1	62207025	Missense_Mutation	novel	L133V	0.3
UCEC	chr1	62207176	Missense_Mutation	rs773253339	D183G	0.2
UCEC	chr1	62210032	Nonsense_Mutation	novel	E420*	0.32
UCEC	chr1	62210529	Missense_Mutation	novel	K585N	0.3
UCEC	chr1	62207191	Missense_Mutation	novel	R188H	0.05
UCEC	chr1	62209908	Missense_Mutation	NA	E378D	0.08
UCEC	chr1	62210861	Missense_Mutation	NA	R696K	0.18
UCEC	chr1	62206917	Missense_Mutation	NA	S97R	0.13
UCEC	chr1	62210827	Missense_Mutation	novel	I685V	0.08
UCEC	chr1	62207347	Missense_Mutation	novel	G240E	0.15
UCEC	chr1	62210666	Missense_Mutation	NA	E631A	0.37
UCEC	chr1	62210793	Missense_Mutation	NA	F673L	0.43
UCEC	chr1	62209802	Missense_Mutation	novel	S343L	0.24
UCEC	chr1	62206727	Silent	novel	T33T	0.67
UCEC	chr1	62211084	Missense_Mutation	novel	K770N	0.39	Transposase_22
UCEC	chr1	62206675	Missense_Mutation	novel	A16V	0.31
UCEC	chr1	62206743	Missense_Mutation	rs114926803	P39S	0.23
UCEC	chr1	62210545	Missense_Mutation	novel	E591Q	0.44
UCEC	chr1	62210019	Silent	NA	E415E	0.36
UCEC	chr1	62207190	Missense_Mutation	rs541962027	R188C	0.33
UCEC	chr1	62207274	Missense_Mutation	novel	K216Q	0.56
UCEC	chr1	62211346	Nonsense_Mutation	novel	E858*	0.82
UCEC	chr1	62206776	Missense_Mutation	novel	A50S	0.34
UCEC	chr1	62210415	Silent	novel	G547G	0.33
UCEC	chr1	62210407	Nonsense_Mutation	novel	G545*	0.36
UCEC	chr1	62210205	Missense_Mutation	novel	E477D	0.7
UCEC	chr1	62210779	Missense_Mutation	novel	Q669K	0.33
UCEC	chr1	62207205	Nonsense_Mutation	NA	E193*	0.36
UCEC	chr1	62210334	Missense_Mutation	NA	K520N	0.45
UCEC	chr1	62210759	Missense_Mutation	NA	R662K	0.3
UCEC	chr1	62207193	Missense_Mutation	novel	N189D	0.3
UCEC	chr1	62207443	Missense_Mutation	novel	F272C	0.14
UCEC	chr1	62207197	Missense_Mutation	novel	V190A	0.24
UCEC	chr1	62210011	Missense_Mutation	novel	L413M	0.4
UCEC	chr1	62211441	3'UTR	rs574718447		0.28
UCEC	chr1	62210430	Silent	NA	T552T	0.48
UCEC	chr1	62207102	Missense_Mutation	rs367875859	K158N	0.52
UCEC	chr1	62207489	Silent	novel	D287D	0.36
UCEC	chr1	62207439	Missense_Mutation	NA	D271Y	0.47
UCEC	chr1	62210296	Nonsense_Mutation	NA	E508*	0.38
UCEC	chr1	62210790	Missense_Mutation	NA	E672D	0.45
UCEC	chr1	62210854	Missense_Mutation	rs546879656	E694K	0.28
UCEC	chr1	62206901	Missense_Mutation	NA	K91N	0.37
UCEC	chr1	62207527	Missense_Mutation	NA	R300I	0.29
UCEC	chr1	62210253	Missense_Mutation	novel	K493N	0.31
UCEC	chr1	62210793	Missense_Mutation	NA	F673L	0.44
UCEC	chr1	62209789	Missense_Mutation	novel	T339A	0.25
UCEC	chr1	62211102	Silent	novel	A776A	0.31
UCEC	chr1	62211736	3'UTR	novel		0.24
UCEC	chr1	62210463	Missense_Mutation	novel	E563D	0.53
UCEC	chr1	62207464	Missense_Mutation	novel	E279G	0.5
UCEC	chr1	62210061	Silent	NA	A429A	0.4
UCEC	chr1	62211628	3'UTR	novel		0.32
UCEC	chr1	62206992	Nonsense_Mutation	novel	E122*	0.27
UCS	chr1	62210575	Nonsense_Mutation	novel	E601*	0.36

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
COAD	DEL	0.2306	0.00038973
TGCT	DEL	0.16	0.023574

Survival Analysis

Cancer	P-value	Q-value
MESO	0.042	Kaplan-Meier Survival Analysis
LUSC	0.016	Kaplan-Meier Survival Analysis
BRCA	0.0032	Kaplan-Meier Survival Analysis
KIRP	0.021	Kaplan-Meier Survival Analysis
READ	0.037	Kaplan-Meier Survival Analysis
LAML	0.014	Kaplan-Meier Survival Analysis
LGG	0.016	Kaplan-Meier Survival Analysis
LUAD	0.0044	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742