EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000241258 (Gene tree)
Gene ID: 27297
Gene Symbol: CRCP
Alias: CGRP-RCP|RCP|RCP9
Full Name: CGRP receptor component
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 39,965 bases
Position: chr7:66,114,604-66,154,568
Accession: 17888
RBP type: canonical RBP
Summary: This gene encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000378736	RNA_pol_Rpb4	PF03874.16	3.7e-31	1	1
ENSP00000340044	RNA_pol_Rpb4	PF03874.16	5.8e-22	1	1
ENSP00000388653	RNA_pol_Rpb4	PF03874.16	1.2e-21	1	1
ENSP00000381674	RNA_pol_Rpb4	PF03874.16	1.6e-10	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000486848	CRCP-206	458	-	-	- (aa)	-	-
ENST00000398684	CRCP-204	492	-	ENSP00000381674	71 (aa)	-	O75575
ENST00000492264	CRCP-207	731	-	-	- (aa)	-	-
ENST00000395326	CRCP-203	3009	-	ENSP00000378736	148 (aa)	-	O75575
ENST00000338592	CRCP-201	1393	-	ENSP00000340044	115 (aa)	-	O75575
ENST00000431089	CRCP-205	942	-	ENSP00000388653	141 (aa)	-	O75575
ENST00000360415	CRCP-202	3139	-	ENSP00000353589	42 (aa)	-	H7BY40

Gene Model

Click here to download ENSG00000241258's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000241258	Diabetic Nephropathies	8E-6	26305897
ENSG00000241258	Aorta	4E-6	21223598

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000241258	rs2243480	7	66134209	?	Diabetic kidney disease	26305897	[1.2-1.64]	1.4084507	EFO_0000401
ENSG00000241258	rs875971	7	66152608	?	Aortic root size	21223598	[0.063-0.151] cm increase	0.1069	EFO_0005037

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000241258's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000241258	CRCP	97	73.611	ENSAPOG00000016572	crcp	97	73.611	Acanthochromis_polyacanthus
ENSG00000241258	CRCP	98	95.172	ENSAMEG00000015954	CRCP	99	95.172	Ailuropoda_melanoleuca
ENSG00000241258	CRCP	93	71.014	ENSACIG00000020248	crcp	91	71.014	Amphilophus_citrinellus
ENSG00000241258	CRCP	97	73.611	ENSAOCG00000021389	crcp	97	73.611	Amphiprion_ocellaris
ENSG00000241258	CRCP	97	62.500	ENSAPEG00000016688	crcp	96	62.500	Amphiprion_percula
ENSG00000241258	CRCP	97	72.917	ENSATEG00000008670	crcp	97	72.917	Anabas_testudineus
ENSG00000241258	CRCP	100	97.297	ENSANAG00000032466	CRCP	100	97.297	Aotus_nancymaae
ENSG00000241258	CRCP	89	80.153	ENSACLG00000007588	crcp	89	80.153	Astatotilapia_calliptera
ENSG00000241258	CRCP	87	74.419	ENSAMXG00000043940	crcp	88	74.419	Astyanax_mexicanus
ENSG00000241258	CRCP	100	91.892	ENSBTAG00000049986	-	100	91.892	Bos_taurus
ENSG00000241258	CRCP	100	93.243	ENSBTAG00000037489	CRCP	100	93.243	Bos_taurus
ENSG00000241258	CRCP	86	41.085	WBGene00044924	M106.7	98	40.310	Caenorhabditis_elegans
ENSG00000241258	CRCP	100	95.270	ENSCJAG00000004225	CRCP	100	95.270	Callithrix_jacchus
ENSG00000241258	CRCP	100	93.243	ENSCAFG00000010756	CRCP	100	93.243	Canis_familiaris
ENSG00000241258	CRCP	100	93.919	ENSCAFG00020005322	CRCP	100	93.919	Canis_lupus_dingo
ENSG00000241258	CRCP	95	86.525	ENSCHIG00000015299	CRCP	90	86.525	Capra_hircus
ENSG00000241258	CRCP	100	94.595	ENSTSYG00000005933	CRCP	100	94.595	Carlito_syrichta
ENSG00000241258	CRCP	100	94.366	ENSCCAG00000012341	-	100	94.366	Cebus_capucinus
ENSG00000241258	CRCP	100	95.775	ENSCATG00000036957	CRCP	100	95.775	Cercocebus_atys
ENSG00000241258	CRCP	100	85.906	ENSCLAG00000007249	CRCP	100	87.919	Chinchilla_lanigera
ENSG00000241258	CRCP	96	95.588	ENSCSAG00000018288	CRCP	75	96.992	Chlorocebus_sabaeus
ENSG00000241258	CRCP	99	77.551	ENSCPBG00000014854	CRCP	99	77.551	Chrysemys_picta_bellii
ENSG00000241258	CRCP	75	59.302	ENSCING00000003588	cgrp-rcp	93	55.932	Ciona_intestinalis
ENSG00000241258	CRCP	100	97.973	ENSCANG00000038796	CRCP	100	97.973	Colobus_angolensis_palliatus
ENSG00000241258	CRCP	100	87.838	ENSCGRG00001009376	Crcp	100	87.838	Cricetulus_griseus_chok1gshd
ENSG00000241258	CRCP	100	87.162	ENSCGRG00000003194	Crcp	100	87.162	Cricetulus_griseus_crigri
ENSG00000241258	CRCP	95	70.213	ENSCSEG00000018814	crcp	93	70.714	Cynoglossus_semilaevis
ENSG00000241258	CRCP	97	69.444	ENSCVAG00000013625	crcp	97	69.444	Cyprinodon_variegatus
ENSG00000241258	CRCP	97	74.126	ENSDARG00000069373	crcp	98	74.126	Danio_rerio
ENSG00000241258	CRCP	100	93.243	ENSDNOG00000002751	CRCP	100	93.243	Dasypus_novemcinctus
ENSG00000241258	CRCP	98	90.345	ENSDORG00000013712	Crcp	100	90.345	Dipodomys_ordii
ENSG00000241258	CRCP	100	93.919	ENSEASG00005008835	CRCP	100	93.919	Equus_asinus_asinus
ENSG00000241258	CRCP	98	94.483	ENSECAG00000011060	CRCP	98	94.483	Equus_caballus
ENSG00000241258	CRCP	96	88.235	ENSEEUG00000005796	-	100	85.606	Erinaceus_europaeus
ENSG00000241258	CRCP	89	78.626	ENSELUG00000019916	crcp	88	78.626	Esox_lucius
ENSG00000241258	CRCP	100	93.919	ENSFCAG00000022099	CRCP	100	93.919	Felis_catus
ENSG00000241258	CRCP	99	81.507	ENSFALG00000006720	CRCP	99	81.507	Ficedula_albicollis
ENSG00000241258	CRCP	100	85.235	ENSFDAG00000014337	CRCP	100	87.248	Fukomys_damarensis
ENSG00000241258	CRCP	97	72.222	ENSFHEG00000021283	crcp	97	72.222	Fundulus_heteroclitus
ENSG00000241258	CRCP	93	75.912	ENSGMOG00000011351	crcp	98	75.912	Gadus_morhua
ENSG00000241258	CRCP	90	85.714	ENSGALG00000002587	CRCP	92	85.714	Gallus_gallus
ENSG00000241258	CRCP	97	72.222	ENSGAFG00000002307	crcp	97	72.222	Gambusia_affinis
ENSG00000241258	CRCP	89	78.626	ENSGACG00000020468	crcp	92	78.626	Gasterosteus_aculeatus
ENSG00000241258	CRCP	99	78.912	ENSGAGG00000011445	CRCP	95	78.082	Gopherus_agassizii
ENSG00000241258	CRCP	100	100.000	ENSGGOG00000039733	CRCP	100	100.000	Gorilla_gorilla
ENSG00000241258	CRCP	89	79.389	ENSHBUG00000004779	crcp	89	79.389	Haplochromis_burtoni
ENSG00000241258	CRCP	100	82.550	ENSHGLG00000011719	CRCP	100	84.564	Heterocephalus_glaber_female
ENSG00000241258	CRCP	98	80.272	ENSHGLG00100005071	CRCP	100	80.272	Heterocephalus_glaber_male
ENSG00000241258	CRCP	93	70.290	ENSHCOG00000009105	crcp	98	70.290	Hippocampus_comes
ENSG00000241258	CRCP	89	77.863	ENSIPUG00000024520	CRCP	90	77.863	Ictalurus_punctatus
ENSG00000241258	CRCP	96	89.706	ENSSTOG00000008885	CRCP	100	93.985	Ictidomys_tridecemlineatus
ENSG00000241258	CRCP	100	91.216	ENSJJAG00000016893	Crcp	100	91.216	Jaculus_jaculus
ENSG00000241258	CRCP	86	78.125	ENSKMAG00000007300	crcp	89	77.863	Kryptolebias_marmoratus
ENSG00000241258	CRCP	97	70.139	ENSLBEG00000000804	crcp	97	70.139	Labrus_bergylta
ENSG00000241258	CRCP	87	79.845	ENSLOCG00000005302	crcp	88	79.845	Lepisosteus_oculatus
ENSG00000241258	CRCP	98	91.034	ENSLAFG00000027377	CRCP	100	91.034	Loxodonta_africana
ENSG00000241258	CRCP	100	96.622	ENSMFAG00000037828	CRCP	100	96.622	Macaca_fascicularis
ENSG00000241258	CRCP	100	96.622	ENSMMUG00000014524	CRCP	100	96.622	Macaca_mulatta
ENSG00000241258	CRCP	67	84.848	ENSMNEG00000030945	CRCP	97	84.848	Macaca_nemestrina
ENSG00000241258	CRCP	100	96.622	ENSMLEG00000043904	CRCP	100	96.622	Mandrillus_leucophaeus
ENSG00000241258	CRCP	89	79.389	ENSMAMG00000021168	crcp	90	79.389	Mastacembelus_armatus
ENSG00000241258	CRCP	89	80.153	ENSMZEG00005025255	crcp	89	80.153	Maylandia_zebra
ENSG00000241258	CRCP	89	84.848	ENSMGAG00000004593	CRCP	91	84.848	Meleagris_gallopavo
ENSG00000241258	CRCP	57	89.286	ENSMAUG00000018383	Crcp	100	89.286	Mesocricetus_auratus
ENSG00000241258	CRCP	100	95.946	ENSMICG00000004191	CRCP	100	95.946	Microcebus_murinus
ENSG00000241258	CRCP	98	88.276	ENSMOCG00000002717	Crcp	98	88.276	Microtus_ochrogaster
ENSG00000241258	CRCP	93	75.362	ENSMMOG00000011491	crcp	87	75.362	Mola_mola
ENSG00000241258	CRCP	95	71.631	ENSMALG00000020309	crcp	96	71.631	Monopterus_albus
ENSG00000241258	CRCP	100	88.514	MGP_CAROLIEiJ_G0027795	Crcp	100	88.514	Mus_caroli
ENSG00000241258	CRCP	100	88.514	ENSMUSG00000025532	Crcp	100	88.514	Mus_musculus
ENSG00000241258	CRCP	100	88.514	MGP_PahariEiJ_G0024389	Crcp	100	88.514	Mus_pahari
ENSG00000241258	CRCP	100	89.865	MGP_SPRETEiJ_G0028793	Crcp	100	89.865	Mus_spretus
ENSG00000241258	CRCP	99	89.726	ENSMPUG00000016198	CRCP	100	89.726	Mustela_putorius_furo
ENSG00000241258	CRCP	98	93.103	ENSMLUG00000012217	CRCP	100	93.103	Myotis_lucifugus
ENSG00000241258	CRCP	100	90.541	ENSNGAG00000021687	Crcp	100	90.541	Nannospalax_galili
ENSG00000241258	CRCP	79	79.487	ENSNBRG00000003094	crcp	58	79.487	Neolamprologus_brichardi
ENSG00000241258	CRCP	100	98.261	ENSNLEG00000001437	CRCP	100	98.261	Nomascus_leucogenys
ENSG00000241258	CRCP	100	62.838	ENSODEG00000003432	-	100	62.838	Octodon_degus
ENSG00000241258	CRCP	100	84.667	ENSODEG00000020033	-	100	86.667	Octodon_degus
ENSG00000241258	CRCP	98	84.932	ENSODEG00000014255	-	100	86.986	Octodon_degus
ENSG00000241258	CRCP	97	64.384	ENSONIG00000008677	crcp	97	64.384	Oreochromis_niloticus
ENSG00000241258	CRCP	74	85.455	ENSOANG00000009026	-	74	90.099	Ornithorhynchus_anatinus
ENSG00000241258	CRCP	100	92.568	ENSOCUG00000014827	CRCP	100	92.568	Oryctolagus_cuniculus
ENSG00000241258	CRCP	89	77.099	ENSORLG00000028784	crcp	89	77.099	Oryzias_latipes
ENSG00000241258	CRCP	89	76.336	ENSORLG00020017373	crcp	89	76.336	Oryzias_latipes_hni
ENSG00000241258	CRCP	89	76.336	ENSORLG00015001859	crcp	89	76.336	Oryzias_latipes_hsok
ENSG00000241258	CRCP	89	77.099	ENSOMEG00000008006	crcp	89	77.099	Oryzias_melastigma
ENSG00000241258	CRCP	97	90.000	ENSOGAG00000001914	CRCP	100	80.137	Otolemur_garnettii
ENSG00000241258	CRCP	86	96.063	ENSOARG00000010380	-	53	93.130	Ovis_aries
ENSG00000241258	CRCP	100	100.000	ENSPPAG00000030427	CRCP	100	100.000	Pan_paniscus
ENSG00000241258	CRCP	100	93.919	ENSPPRG00000012841	CRCP	100	93.919	Panthera_pardus
ENSG00000241258	CRCP	98	89.116	ENSPTIG00000009335	CRCP	100	89.116	Panthera_tigris_altaica
ENSG00000241258	CRCP	100	100.000	ENSPTRG00000046581	CRCP	100	100.000	Pan_troglodytes
ENSG00000241258	CRCP	98	100.000	ENSPTRG00000019246	-	98	100.000	Pan_troglodytes
ENSG00000241258	CRCP	100	96.622	ENSPANG00000023118	CRCP	100	96.622	Papio_anubis
ENSG00000241258	CRCP	86	80.469	ENSPKIG00000011467	crcp	87	80.469	Paramormyrops_kingsleyae
ENSG00000241258	CRCP	86	83.594	ENSPSIG00000008385	CRCP	85	83.594	Pelodiscus_sinensis
ENSG00000241258	CRCP	95	73.050	ENSPMGG00000005986	crcp	95	73.050	Periophthalmus_magnuspinnatus
ENSG00000241258	CRCP	100	88.514	ENSPEMG00000010829	Crcp	100	88.514	Peromyscus_maniculatus_bairdii
ENSG00000241258	CRCP	89	76.336	ENSPFOG00000008626	crcp	89	76.336	Poecilia_formosa
ENSG00000241258	CRCP	89	76.336	ENSPLAG00000005996	crcp	89	76.336	Poecilia_latipinna
ENSG00000241258	CRCP	89	76.336	ENSPMEG00000020035	crcp	89	76.336	Poecilia_mexicana
ENSG00000241258	CRCP	67	78.788	ENSPREG00000008487	crcp	73	78.788	Poecilia_reticulata
ENSG00000241258	CRCP	100	98.649	ENSPPYG00000017525	CRCP	100	98.649	Pongo_abelii
ENSG00000241258	CRCP	89	79.389	ENSPNYG00000016988	crcp	89	79.389	Pundamilia_nyererei
ENSG00000241258	CRCP	97	74.126	ENSPNAG00000004712	crcp	97	74.126	Pygocentrus_nattereri
ENSG00000241258	CRCP	99	86.395	ENSRNOG00000000901	Crcp	100	86.395	Rattus_norvegicus
ENSG00000241258	CRCP	98	97.931	ENSRBIG00000039256	CRCP	100	97.321	Rhinopithecus_bieti
ENSG00000241258	CRCP	98	97.931	ENSRROG00000037982	CRCP	100	97.321	Rhinopithecus_roxellana
ENSG00000241258	CRCP	82	30.818	YJL011C	RPC17	99	30.818	Saccharomyces_cerevisiae
ENSG00000241258	CRCP	100	95.270	ENSSBOG00000011617	-	100	95.270	Saimiri_boliviensis_boliviensis
ENSG00000241258	CRCP	98	95.862	ENSSBOG00000025998	-	100	95.862	Saimiri_boliviensis_boliviensis
ENSG00000241258	CRCP	97	82.639	ENSSHAG00000007315	CRCP	97	82.639	Sarcophilus_harrisii
ENSG00000241258	CRCP	98	73.103	ENSSFOG00015013799	crcp	97	73.103	Scleropages_formosus
ENSG00000241258	CRCP	86	78.125	ENSSMAG00000019004	crcp	89	77.863	Scophthalmus_maximus
ENSG00000241258	CRCP	89	80.916	ENSSDUG00000019628	crcp	93	74.615	Seriola_dumerili
ENSG00000241258	CRCP	89	80.153	ENSSLDG00000016367	crcp	89	80.153	Seriola_lalandi_dorsalis
ENSG00000241258	CRCP	92	80.147	ENSSPUG00000002367	CRCP	93	80.147	Sphenodon_punctatus
ENSG00000241258	CRCP	89	78.626	ENSSPAG00000010443	crcp	96	73.333	Stegastes_partitus
ENSG00000241258	CRCP	88	69.466	ENSSSCG00000031397	-	74	76.238	Sus_scrofa
ENSG00000241258	CRCP	88	67.176	ENSSSCG00000034001	-	73	73.267	Sus_scrofa
ENSG00000241258	CRCP	100	92.568	ENSSSCG00000032119	-	100	92.568	Sus_scrofa
ENSG00000241258	CRCP	76	69.643	ENSSSCG00000039653	-	100	57.432	Sus_scrofa
ENSG00000241258	CRCP	65	87.500	ENSTGUG00000005354	CRCP	100	87.500	Taeniopygia_guttata
ENSG00000241258	CRCP	98	71.034	ENSTRUG00000025161	crcp	97	71.034	Takifugu_rubripes
ENSG00000241258	CRCP	98	70.748	ENSTNIG00000016137	crcp	97	70.748	Tetraodon_nigroviridis
ENSG00000241258	CRCP	100	93.919	ENSTTRG00000002888	CRCP	100	93.919	Tursiops_truncatus
ENSG00000241258	CRCP	100	93.919	ENSUMAG00000015406	CRCP	100	93.919	Ursus_maritimus
ENSG00000241258	CRCP	98	95.862	ENSVPAG00000006107	CRCP	100	95.862	Vicugna_pacos
ENSG00000241258	CRCP	100	93.919	ENSVVUG00000016521	CRCP	100	93.919	Vulpes_vulpes
ENSG00000241258	CRCP	88	78.462	ENSXETG00000025028	crcp	91	77.863	Xenopus_tropicalis
ENSG00000241258	CRCP	80	73.109	ENSXCOG00000007013	crcp	76	73.109	Xiphophorus_couchianus
ENSG00000241258	CRCP	87	75.969	ENSXMAG00000022222	crcp	97	70.833	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000166	nucleotide binding	-	IEA	Function
GO:0001056	RNA polymerase III activity	21873635.	IBA	Function
GO:0001635	calcitonin gene-related peptide receptor activity	-	IEA	Function
GO:0001669	acrosomal vesicle	-	IEA	Component
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	12482973.	IDA	Function
GO:0005515	protein binding	25416956.	IPI	Function
GO:0005623	cell	11804624.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005666	RNA polymerase III complex	21873635.	IBA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005886	plasma membrane	-	IEA	Component
GO:0006383	transcription by RNA polymerase III	12482973.	IDA	Process
GO:0006384	transcription initiation from RNA polymerase III promoter	21873635.	IBA	Process
GO:0007218	neuropeptide signaling pathway	-	IEA	Process
GO:0009360	DNA polymerase III complex	12482973.	IDA	Component
GO:0032481	positive regulation of type I interferon production	-	TAS	Process
GO:0045087	innate immune response	-	IEA	Process
GO:0051607	defense response to virus	-	IEA	Process