EuRBPDB

Description

RBDs

RBPome

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000247315 (Gene tree)
Gene ID: 85364
Gene Symbol: ZCCHC3
Alias: dJ1103G7.7|C20orf99
Full Name: zinc finger CCHC-type containing 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 3,354 bases
Position: chr20:296,968-300,321
Accession: 16230
RBP type: canonical RBP
Summary: (Zinc Finger CCHC-Type Containing 3) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000484056	zf-CCHC	PF00098.23	4.2e-06	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000500893	ZCCHC3-201	3354	-	ENSP00000484056	403 (aa)	-	Q9NUD5

Gene Model

Click here to download ENSG00000247315's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000247315	Bipolar Disorder	6.19E-5	19488044
ENSG00000247315	Pulse Wave Analysis	6.049e-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000247315's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000247315	ZCCHC3	67	94.776	ENSAMEG00000013999	ZCCHC3	86	95.113	Ailuropoda_melanoleuca
ENSG00000247315	ZCCHC3	100	93.797	ENSANAG00000013484	ZCCHC3	100	93.052	Aotus_nancymaae
ENSG00000247315	ZCCHC3	77	31.613	ENSACLG00000026211	-	50	33.471	Astatotilapia_calliptera
ENSG00000247315	ZCCHC3	52	30.806	ENSACLG00000019767	-	50	30.806	Astatotilapia_calliptera
ENSG00000247315	ZCCHC3	62	31.621	ENSACLG00000024271	-	71	31.621	Astatotilapia_calliptera
ENSG00000247315	ZCCHC3	50	31.220	ENSACLG00000019815	-	51	30.841	Astatotilapia_calliptera
ENSG00000247315	ZCCHC3	72	33.106	ENSAMXG00000037658	-	76	33.462	Astyanax_mexicanus
ENSG00000247315	ZCCHC3	58	30.213	ENSAMXG00000035044	-	65	30.213	Astyanax_mexicanus
ENSG00000247315	ZCCHC3	51	30.374	ENSAMXG00000033087	-	63	30.374	Astyanax_mexicanus
ENSG00000247315	ZCCHC3	62	30.800	ENSAMXG00000029829	-	58	30.992	Astyanax_mexicanus
ENSG00000247315	ZCCHC3	100	91.892	ENSBTAG00000002116	ZCCHC3	100	90.418	Bos_taurus
ENSG00000247315	ZCCHC3	100	96.543	ENSCJAG00000020839	ZCCHC3	100	96.543	Callithrix_jacchus
ENSG00000247315	ZCCHC3	61	99.592	ENSCAFG00000025206	ZCCHC3	91	96.484	Canis_familiaris
ENSG00000247315	ZCCHC3	100	92.629	ENSCAFG00020004076	ZCCHC3	100	92.383	Canis_lupus_dingo
ENSG00000247315	ZCCHC3	100	91.155	ENSCHIG00000009882	ZCCHC3	100	90.909	Capra_hircus
ENSG00000247315	ZCCHC3	100	84.901	ENSCPOG00000023974	ZCCHC3	100	84.615	Cavia_porcellus
ENSG00000247315	ZCCHC3	100	93.842	ENSCCAG00000016869	ZCCHC3	100	93.350	Cebus_capucinus
ENSG00000247315	ZCCHC3	100	98.263	ENSCATG00000022200	ZCCHC3	100	98.263	Cercocebus_atys
ENSG00000247315	ZCCHC3	100	91.811	ENSCLAG00000000269	ZCCHC3	100	91.811	Chinchilla_lanigera
ENSG00000247315	ZCCHC3	100	98.263	ENSCSAG00000018761	ZCCHC3	100	98.263	Chlorocebus_sabaeus
ENSG00000247315	ZCCHC3	66	97.727	ENSCANG00000010812	ZCCHC3	95	97.727	Colobus_angolensis_palliatus
ENSG00000247315	ZCCHC3	88	81.020	ENSCGRG00001011895	-	88	84.211	Cricetulus_griseus_chok1gshd
ENSG00000247315	ZCCHC3	100	86.914	ENSCGRG00001009163	-	100	84.198	Cricetulus_griseus_chok1gshd
ENSG00000247315	ZCCHC3	88	81.020	ENSCGRG00000008273	-	88	84.211	Cricetulus_griseus_crigri
ENSG00000247315	ZCCHC3	100	89.926	ENSDNOG00000047357	ZCCHC3	100	89.435	Dasypus_novemcinctus
ENSG00000247315	ZCCHC3	100	92.822	ENSEASG00005003629	ZCCHC3	100	93.069	Equus_asinus_asinus
ENSG00000247315	ZCCHC3	100	92.822	ENSECAG00000001035	ZCCHC3	100	92.574	Equus_caballus
ENSG00000247315	ZCCHC3	66	35.556	ENSELUG00000017799	-	85	35.688	Esox_lucius
ENSG00000247315	ZCCHC3	100	90.954	ENSFCAG00000026760	ZCCHC3	100	92.176	Felis_catus
ENSG00000247315	ZCCHC3	81	100.000	ENSGGOG00000044213	ZCCHC3	100	100.000	Gorilla_gorilla
ENSG00000247315	ZCCHC3	62	32.932	ENSHBUG00000005879	-	90	33.065	Haplochromis_burtoni
ENSG00000247315	ZCCHC3	100	89.578	ENSHGLG00000019351	ZCCHC3	100	89.578	Heterocephalus_glaber_female
ENSG00000247315	ZCCHC3	65	89.513	ENSHGLG00100009699	ZCCHC3	77	89.513	Heterocephalus_glaber_male
ENSG00000247315	ZCCHC3	51	37.799	ENSIPUG00000000506	-	54	37.799	Ictalurus_punctatus
ENSG00000247315	ZCCHC3	100	86.029	ENSJJAG00000020375	Zcchc3	100	84.559	Jaculus_jaculus
ENSG00000247315	ZCCHC3	73	33.439	ENSLACG00000022202	-	56	40.708	Latimeria_chalumnae
ENSG00000247315	ZCCHC3	58	37.931	ENSLACG00000012103	-	68	37.931	Latimeria_chalumnae
ENSG00000247315	ZCCHC3	52	36.667	ENSLACG00000000032	-	59	36.667	Latimeria_chalumnae
ENSG00000247315	ZCCHC3	59	38.075	ENSLACG00000002300	-	72	38.075	Latimeria_chalumnae
ENSG00000247315	ZCCHC3	67	33.579	ENSLACG00000002864	-	78	37.607	Latimeria_chalumnae
ENSG00000247315	ZCCHC3	71	32.302	ENSLACG00000003445	-	56	36.564	Latimeria_chalumnae
ENSG00000247315	ZCCHC3	58	37.931	ENSLACG00000004809	-	54	36.187	Latimeria_chalumnae
ENSG00000247315	ZCCHC3	52	38.389	ENSLACG00000003328	-	75	38.389	Latimeria_chalumnae
ENSG00000247315	ZCCHC3	53	38.679	ENSLACG00000022551	-	55	38.679	Latimeria_chalumnae
ENSG00000247315	ZCCHC3	57	38.261	ENSLACG00000002973	-	60	38.261	Latimeria_chalumnae
ENSG00000247315	ZCCHC3	58	37.931	ENSLACG00000012216	-	75	37.931	Latimeria_chalumnae
ENSG00000247315	ZCCHC3	59	32.645	ENSLOCG00000017623	-	97	32.645	Lepisosteus_oculatus
ENSG00000247315	ZCCHC3	76	30.915	ENSLOCG00000000227	-	98	30.915	Lepisosteus_oculatus
ENSG00000247315	ZCCHC3	66	95.588	ENSLAFG00000030593	ZCCHC3	100	95.588	Loxodonta_africana
ENSG00000247315	ZCCHC3	100	98.263	ENSMFAG00000044780	ZCCHC3	100	98.263	Macaca_fascicularis
ENSG00000247315	ZCCHC3	100	98.263	ENSMMUG00000038935	ZCCHC3	100	98.263	Macaca_mulatta
ENSG00000247315	ZCCHC3	100	98.263	ENSMNEG00000000405	ZCCHC3	100	98.263	Macaca_nemestrina
ENSG00000247315	ZCCHC3	62	32.016	ENSMZEG00005000499	-	71	32.016	Maylandia_zebra
ENSG00000247315	ZCCHC3	52	30.698	ENSMZEG00005025868	-	51	30.698	Maylandia_zebra
ENSG00000247315	ZCCHC3	52	30.806	ENSMZEG00005028125	-	50	30.806	Maylandia_zebra
ENSG00000247315	ZCCHC3	53	30.942	ENSMZEG00005008237	-	61	30.942	Maylandia_zebra
ENSG00000247315	ZCCHC3	50	31.863	ENSMZEG00005024527	-	50	31.863	Maylandia_zebra
ENSG00000247315	ZCCHC3	52	30.698	ENSMZEG00005025869	-	51	30.698	Maylandia_zebra
ENSG00000247315	ZCCHC3	52	30.698	ENSMZEG00005025871	-	51	30.698	Maylandia_zebra
ENSG00000247315	ZCCHC3	100	93.548	ENSMICG00000031267	ZCCHC3	100	92.308	Microcebus_murinus
ENSG00000247315	ZCCHC3	100	86.849	ENSMOCG00000002870	Zcchc3	100	84.119	Microtus_ochrogaster
ENSG00000247315	ZCCHC3	56	34.802	ENSMMOG00000004516	-	71	33.755	Mola_mola
ENSG00000247315	ZCCHC3	100	86.207	MGP_CAROLIEiJ_G0024454	Zcchc3	100	84.444	Mus_caroli
ENSG00000247315	ZCCHC3	100	86.207	ENSMUSG00000074682	Zcchc3	100	84.444	Mus_musculus
ENSG00000247315	ZCCHC3	100	86.207	MGP_PahariEiJ_G0025898	Zcchc3	100	84.444	Mus_pahari
ENSG00000247315	ZCCHC3	100	86.453	MGP_SPRETEiJ_G0025375	Zcchc3	100	84.691	Mus_spretus
ENSG00000247315	ZCCHC3	100	85.608	ENSNGAG00000006074	Zcchc3	100	82.878	Nannospalax_galili
ENSG00000247315	ZCCHC3	53	31.818	ENSNBRG00000024091	-	60	31.818	Neolamprologus_brichardi
ENSG00000247315	ZCCHC3	100	94.293	ENSNLEG00000009533	ZCCHC3	100	94.293	Nomascus_leucogenys
ENSG00000247315	ZCCHC3	100	89.756	ENSOPRG00000005081	ZCCHC3	100	90.488	Ochotona_princeps
ENSG00000247315	ZCCHC3	100	90.099	ENSODEG00000010730	ZCCHC3	100	89.356	Octodon_degus
ENSG00000247315	ZCCHC3	100	87.593	ENSOCUG00000017024	ZCCHC3	100	88.089	Oryctolagus_cuniculus
ENSG00000247315	ZCCHC3	100	90.909	ENSOGAG00000025208	ZCCHC3	100	90.909	Otolemur_garnettii
ENSG00000247315	ZCCHC3	65	96.241	ENSOARG00000019161	ZCCHC3	94	96.296	Ovis_aries
ENSG00000247315	ZCCHC3	65	98.864	ENSPPAG00000010453	-	99	98.864	Pan_paniscus
ENSG00000247315	ZCCHC3	100	91.155	ENSPPRG00000014724	ZCCHC3	100	92.383	Panthera_pardus
ENSG00000247315	ZCCHC3	61	91.837	ENSPTIG00000009393	ZCCHC3	100	91.837	Panthera_tigris_altaica
ENSG00000247315	ZCCHC3	100	99.015	ENSPTRG00000047645	ZCCHC3	100	99.015	Pan_troglodytes
ENSG00000247315	ZCCHC3	100	98.511	ENSPANG00000013450	ZCCHC3	100	98.511	Papio_anubis
ENSG00000247315	ZCCHC3	100	82.310	ENSPEMG00000009059	Zcchc3	100	81.572	Peromyscus_maniculatus_bairdii
ENSG00000247315	ZCCHC3	90	88.315	ENSPCAG00000008034	ZCCHC3	100	87.772	Procavia_capensis
ENSG00000247315	ZCCHC3	100	94.045	ENSPCOG00000012289	ZCCHC3	100	93.300	Propithecus_coquereli
ENSG00000247315	ZCCHC3	100	91.155	ENSPVAG00000000182	ZCCHC3	100	89.681	Pteropus_vampyrus
ENSG00000247315	ZCCHC3	52	31.336	ENSPNYG00000003800	-	51	31.336	Pundamilia_nyererei
ENSG00000247315	ZCCHC3	100	85.468	ENSRNOG00000007520	Zcchc3	100	83.951	Rattus_norvegicus
ENSG00000247315	ZCCHC3	100	98.511	ENSRBIG00000029757	ZCCHC3	100	98.511	Rhinopithecus_bieti
ENSG00000247315	ZCCHC3	100	98.511	ENSRROG00000005210	ZCCHC3	100	98.511	Rhinopithecus_roxellana
ENSG00000247315	ZCCHC3	100	92.875	ENSSSCG00000007211	ZCCHC3	100	92.138	Sus_scrofa
ENSG00000247315	ZCCHC3	100	91.892	ENSTTRG00000008511	ZCCHC3	100	90.418	Tursiops_truncatus
ENSG00000247315	ZCCHC3	100	83.824	ENSUAMG00000023407	ZCCHC3	100	83.784	Ursus_americanus
ENSG00000247315	ZCCHC3	61	96.341	ENSVPAG00000011267	-	100	96.341	Vicugna_pacos
ENSG00000247315	ZCCHC3	63	38.340	ENSXETG00000005590	-	100	35.179	Xenopus_tropicalis
ENSG00000247315	ZCCHC3	64	38.132	ENSXETG00000033341	-	94	44.295	Xenopus_tropicalis
ENSG00000247315	ZCCHC3	53	36.239	ENSXCOG00000010666	-	57	35.321	Xiphophorus_couchianus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0002218	activation of innate immune response	30135424.30193849.	IDA	Process
GO:0003690	double-stranded DNA binding	30135424.	IDA	Function
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	30135424.30193849.	IPI	Function
GO:0005737	cytoplasm	30135424.	IDA	Component
GO:0008270	zinc ion binding	-	IEA	Function
GO:0009597	detection of virus	30135424.30193849.	IDA	Process
GO:0032481	positive regulation of type I interferon production	-	IEA	Process
GO:0045087	innate immune response	-	IEA	Process
GO:0051607	defense response to virus	-	IEA	Process
GO:0071360	cellular response to exogenous dsRNA	30193849.	IMP	Process
GO:1900246	positive regulation of RIG-I signaling pathway	30193849.	IDA	Process