EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000250305 (Gene tree)
Gene ID: 57604
Gene Symbol: TRMT9B
Alias: FLJ36980|TRM9L|hTRM9L|C8orf79|KIAA1456
Full Name: tRNA methyltransferase 9B (putative)
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 85,862 bases
Position: chr8:12,945,642-13,031,503
Accession: 26725
RBP type: canonical RBP
Summary: TRMT9B (TRNA Methyltransferase 9B (Putative)) is a Protein Coding gene. Among its related pathways are Gene Expression and tRNA processing. An important paralog of this gene is ALKBH8.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000432695	Methyltransf_31	PF13847.6	3e-09	1	1
ENSP00000432695	Methyltransf_8	PF05148.15	3.7e-05	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000532376	TRMT9B-209	668	-	ENSP00000431717	54 (aa)	-	E9PK20
ENST00000400069	TRMT9B-201	1982	-	ENSP00000468715	60 (aa)	-	Q9P272
ENST00000525249	TRMT9B-204	553	-	-	- (aa)	-	-
ENST00000529978	TRMT9B-208	6003	-	-	- (aa)	-	-
ENST00000447063	TRMT9B-202	983	-	ENSP00000443288	196 (aa)	-	F6XBY7
ENST00000524591	TRMT9B-203	9587	XM_005273584	ENSP00000432695	454 (aa)	XP_005273641	Q9P272
ENST00000529706	TRMT9B-207	2758	-	-	- (aa)	-	-
ENST00000528753	TRMT9B-206	2392	-	ENSP00000466330	60 (aa)	-	Q9P272
ENST00000528335	TRMT9B-205	579	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000250305's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000250305	Arteries	1.9560000E-005	-
ENSG00000250305	Platelet Function Tests	1.4169400E-005	-
ENSG00000250305	Child Development Disorders, Pervasive	6.1462000E-006	-
ENSG00000250305	Child Development Disorders, Pervasive	3.7093000E-006	-
ENSG00000250305	Child Development Disorders, Pervasive	1.5734000E-005	-
ENSG00000250305	Child Development Disorders, Pervasive	2.0084000E-005	-
ENSG00000250305	S-(3-hydroxypropyl)cysteine N-acetate	3E-6	26053186
ENSG00000250305	Smoking	3E-6	26053186
ENSG00000250305	Diabetes Mellitus, Type 2	4E-6	26818947
ENSG00000250305	Bronchodilator Agents	2E-6	26634245
ENSG00000250305	Lung Volume Measurements	2E-6	26634245
ENSG00000250305	Migraine Disorders	9E-6	23793025
ENSG00000250305	Bronchodilator Agents	2E-6	26634245
ENSG00000250305	Lung Volume Measurements	2E-6	26634245
ENSG00000250305	Stress Disorders, Post-Traumatic	5E-6	24677629

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000250305	rs2946504	8	12954071	T	Type 2 diabetes	26818947	[1.04-1.09]	1.06	EFO_0001360
ENSG00000250305	rs2946505	8	12953643	?	Migraine	23793025	[1.03-1.09]	1.06	EFO_0003821
ENSG00000250305	rs2460905	8	12977091	?	Post-traumatic stress disorder	24677629	[0.79-1.97] unit increase	1.38	EFO_0001358
ENSG00000250305	rs2466254	8	12976853	?	Pneumonia	28928442	[0.029-0.073] unit increase	0.0507	EFO_0008410

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000250305's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000250305	TRMT9B	100	92.593	ENSAMEG00000007166	TRMT9B	99	81.111	Ailuropoda_melanoleuca
ENSG00000250305	TRMT9B	100	83.333	ENSAPLG00000009756	TRMT9B	99	60.435	Anas_platyrhynchos
ENSG00000250305	TRMT9B	100	100.000	ENSANAG00000021322	TRMT9B	100	93.172	Aotus_nancymaae
ENSG00000250305	TRMT9B	100	96.296	ENSBTAG00000008950	TRMT9B	100	78.855	Bos_taurus
ENSG00000250305	TRMT9B	100	98.148	ENSCJAG00000012066	TRMT9B	100	92.511	Callithrix_jacchus
ENSG00000250305	TRMT9B	100	96.296	ENSCAFG00000006759	TRMT9B	100	82.159	Canis_familiaris
ENSG00000250305	TRMT9B	100	96.296	ENSCHIG00000025183	TRMT9B	100	79.515	Capra_hircus
ENSG00000250305	TRMT9B	100	96.296	ENSTSYG00000029308	TRMT9B	100	85.683	Carlito_syrichta
ENSG00000250305	TRMT9B	100	92.593	ENSCPOG00000032099	TRMT9B	99	76.222	Cavia_porcellus
ENSG00000250305	TRMT9B	100	98.148	ENSCCAG00000032783	TRMT9B	100	92.731	Cebus_capucinus
ENSG00000250305	TRMT9B	100	98.148	ENSCATG00000037514	TRMT9B	100	94.714	Cercocebus_atys
ENSG00000250305	TRMT9B	100	92.593	ENSCLAG00000000634	TRMT9B	99	79.333	Chinchilla_lanigera
ENSG00000250305	TRMT9B	100	98.148	ENSCSAG00000016833	TRMT9B	100	94.273	Chlorocebus_sabaeus
ENSG00000250305	TRMT9B	100	87.037	ENSCPBG00000025129	TRMT9B	97	62.472	Chrysemys_picta_bellii
ENSG00000250305	TRMT9B	89	93.781	ENSCANG00000025271	TRMT9B	100	93.781	Colobus_angolensis_palliatus
ENSG00000250305	TRMT9B	100	94.444	ENSCGRG00001019764	Trmt9b	99	72.907	Cricetulus_griseus_chok1gshd
ENSG00000250305	TRMT9B	100	94.444	ENSCGRG00000012855	Trmt9b	99	72.907	Cricetulus_griseus_crigri
ENSG00000250305	TRMT9B	100	85.185	ENSDNOG00000000297	TRMT9B	100	73.789	Dasypus_novemcinctus
ENSG00000250305	TRMT9B	100	90.741	ENSDORG00000013664	-	100	88.073	Dipodomys_ordii
ENSG00000250305	TRMT9B	100	94.444	ENSEASG00005017014	TRMT9B	100	83.297	Equus_asinus_asinus
ENSG00000250305	TRMT9B	100	94.444	ENSECAG00000013811	TRMT9B	100	83.700	Equus_caballus
ENSG00000250305	TRMT9B	100	94.444	ENSFCAG00000041381	TRMT9B	100	81.938	Felis_catus
ENSG00000250305	TRMT9B	100	81.481	ENSFALG00000003704	TRMT9B	98	59.695	Ficedula_albicollis
ENSG00000250305	TRMT9B	100	87.037	ENSFDAG00000020217	TRMT9B	99	78.667	Fukomys_damarensis
ENSG00000250305	TRMT9B	100	83.333	ENSGALG00000042726	TRMT9B	99	59.737	Gallus_gallus
ENSG00000250305	TRMT9B	100	87.037	ENSGAGG00000006042	TRMT9B	99	61.062	Gopherus_agassizii
ENSG00000250305	TRMT9B	100	100.000	ENSGGOG00000037983	TRMT9B	100	98.238	Gorilla_gorilla
ENSG00000250305	TRMT9B	100	88.889	ENSHGLG00000004927	TRMT9B	99	81.778	Heterocephalus_glaber_female
ENSG00000250305	TRMT9B	100	90.741	ENSHGLG00100001579	TRMT9B	99	82.000	Heterocephalus_glaber_male
ENSG00000250305	TRMT9B	100	79.630	ENSLACG00000009737	TRMT9B	99	54.013	Latimeria_chalumnae
ENSG00000250305	TRMT9B	100	98.148	ENSMFAG00000043419	TRMT9B	100	94.273	Macaca_fascicularis
ENSG00000250305	TRMT9B	100	98.148	ENSMMUG00000043856	TRMT9B	100	94.273	Macaca_mulatta
ENSG00000250305	TRMT9B	100	98.148	ENSMNEG00000037430	TRMT9B	100	94.273	Macaca_nemestrina
ENSG00000250305	TRMT9B	100	98.148	ENSMLEG00000037379	TRMT9B	100	94.273	Mandrillus_leucophaeus
ENSG00000250305	TRMT9B	100	83.333	ENSMGAG00000011654	TRMT9B	99	60.613	Meleagris_gallopavo
ENSG00000250305	TRMT9B	100	92.593	ENSMAUG00000017514	Trmt9b	99	72.667	Mesocricetus_auratus
ENSG00000250305	TRMT9B	100	96.296	ENSMICG00000012942	TRMT9B	100	84.141	Microcebus_murinus
ENSG00000250305	TRMT9B	100	92.593	ENSMOCG00000013997	Trmt9b	99	70.222	Microtus_ochrogaster
ENSG00000250305	TRMT9B	100	83.333	MGP_CAROLIEiJ_G0030985	Trmt9b	100	74.066	Mus_caroli
ENSG00000250305	TRMT9B	100	83.333	ENSMUSG00000039620	Trmt9b	100	73.568	Mus_musculus
ENSG00000250305	TRMT9B	100	88.889	MGP_PahariEiJ_G0021453	Trmt9b	100	73.789	Mus_pahari
ENSG00000250305	TRMT9B	100	83.333	MGP_SPRETEiJ_G0032101	Trmt9b	100	73.348	Mus_spretus
ENSG00000250305	TRMT9B	100	96.296	ENSMPUG00000011528	TRMT9B	100	79.075	Mustela_putorius_furo
ENSG00000250305	TRMT9B	100	88.889	ENSMLUG00000013029	TRMT9B	100	81.278	Myotis_lucifugus
ENSG00000250305	TRMT9B	100	100.000	ENSNLEG00000031644	TRMT9B	100	95.154	Nomascus_leucogenys
ENSG00000250305	TRMT9B	100	90.741	ENSODEG00000004422	TRMT9B	99	80.222	Octodon_degus
ENSG00000250305	TRMT9B	100	71.186	ENSOANG00000002169	-	79	57.034	Ornithorhynchus_anatinus
ENSG00000250305	TRMT9B	100	92.593	ENSOCUG00000024898	TRMT9B	100	77.074	Oryctolagus_cuniculus
ENSG00000250305	TRMT9B	100	94.444	ENSOGAG00000012709	TRMT9B	100	82.159	Otolemur_garnettii
ENSG00000250305	TRMT9B	100	96.296	ENSOARG00000009832	TRMT9B	99	79.379	Ovis_aries
ENSG00000250305	TRMT9B	100	100.000	ENSPPAG00000030027	TRMT9B	100	97.577	Pan_paniscus
ENSG00000250305	TRMT9B	100	94.444	ENSPPRG00000012143	TRMT9B	100	82.379	Panthera_pardus
ENSG00000250305	TRMT9B	100	94.444	ENSPTIG00000001444	TRMT9B	100	82.599	Panthera_tigris_altaica
ENSG00000250305	TRMT9B	100	100.000	ENSPTRG00000041473	TRMT9B	100	97.797	Pan_troglodytes
ENSG00000250305	TRMT9B	100	98.148	ENSPANG00000008717	TRMT9B	100	94.273	Papio_anubis
ENSG00000250305	TRMT9B	100	92.593	ENSPEMG00000021287	Trmt9b	87	91.892	Peromyscus_maniculatus_bairdii
ENSG00000250305	TRMT9B	100	98.148	ENSPCOG00000020130	TRMT9B	100	85.055	Propithecus_coquereli
ENSG00000250305	TRMT9B	100	90.741	ENSRNOG00000011253	Trmt9b	100	74.229	Rattus_norvegicus
ENSG00000250305	TRMT9B	100	96.296	ENSRBIG00000040588	TRMT9B	100	93.612	Rhinopithecus_bieti
ENSG00000250305	TRMT9B	100	96.296	ENSRROG00000005726	TRMT9B	100	93.392	Rhinopithecus_roxellana
ENSG00000250305	TRMT9B	100	100.000	ENSSBOG00000029215	TRMT9B	100	92.291	Saimiri_boliviensis_boliviensis
ENSG00000250305	TRMT9B	93	86.000	ENSSHAG00000001652	TRMT9B	98	51.663	Sarcophilus_harrisii
ENSG00000250305	TRMT9B	100	92.593	ENSSSCG00000006969	TRMT9B	100	79.956	Sus_scrofa
ENSG00000250305	TRMT9B	100	81.481	ENSTGUG00000007372	TRMT9B	99	58.913	Taeniopygia_guttata
ENSG00000250305	TRMT9B	100	90.741	ENSUMAG00000020549	TRMT9B	100	79.956	Ursus_maritimus
ENSG00000250305	TRMT9B	100	96.296	ENSVVUG00000019651	TRMT9B	100	81.718	Vulpes_vulpes
ENSG00000250305	TRMT9B	100	79.630	ENSXETG00000005622	kiaa1456l	99	50.873	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000049	tRNA binding	21873635.	IBA	Function
GO:0002098	tRNA wobble uridine modification	21873635.	IBA	Process
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	-	TAS	Component
GO:0006400	tRNA modification	-	TAS	Process
GO:0008175	tRNA methyltransferase activity	23381944.	EXP	Function
GO:0016300	tRNA (uracil) methyltransferase activity	21873635.	IBA	Function
GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	21873635.	IBA	Function
GO:0030488	tRNA methylation	-	IEA	Process
GO:0055114	oxidation-reduction process	-	IEA	Process

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
27609572	[Overexpression of KIAA1456 inhibits the proliferation of HO8910PM cells].	Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi	2016 Sep	Chen H	-

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr8	13021061	Missense_Mutation	novel	A128T	0.16	Methyltransf_31
ACC	chr8	13027504	3'UTR	novel		0.26
BLCA	chr8	13022008	Nonsense_Mutation	novel	W443*	0.59
BLCA	chr8	13012835	Silent	rs147161360	F102F	0.33
BLCA	chr8	13021648	Missense_Mutation	rs201727251	W323C	0.1
BLCA	chr8	13021942	Silent	rs551128894	C421C	0.47
BRCA	chr8	13021667	Missense_Mutation	rs757609977	L330V	0.13
BRCA	chr8	13021925	Nonsense_Mutation	rs372924745	R416*	0.06
BRCA	chr8	13021100	Missense_Mutation	rs373979768	V141I	0.55
BRCA	chr8	13012785	Missense_Mutation	novel	E86K	0.13	Methyltransf_31
BRCA	chr8	13022068	3'UTR	novel		0.18
BRCA	chr8	13006253	Silent	rs764131417	Y17Y	0.58
BRCA	chr8	13022055	3'UTR	novel		0.31
BRCA	chr8	13029054	3'UTR	novel		0.18
BRCA	chr8	13006209	Missense_Mutation	NA	H3Y	0.23
CESC	chr8	13027693	3'UTR	novel		0.2
CESC	chr8	13024770	3'UTR	novel		0.25
CESC	chr8	13027277	3'UTR	novel		0.26
CESC	chr8	13022166	3'UTR	novel		0.35
CESC	chr8	13029139	3'UTR	novel		0.49
CESC	chr8	13012724	Silent	novel	V65V	0.37
CESC	chr8	13022229	3'UTR	novel		0.35
CESC	chr8	13022413	3'UTR	novel		0.33
CESC	chr8	13022755	3'UTR	novel		0.33
CESC	chr8	13024391	3'UTR	novel		0.31
CESC	chr8	13024945	3'UTR	rs532354483		0.29
CESC	chr8	13025821	3'UTR	rs531178627		0.39
CESC	chr8	13022229	3'UTR	novel		0.43
CESC	chr8	13028297	3'UTR	novel		0.28
CESC	chr8	13024905	3'UTR	novel		0.65
CESC	chr8	13023101	3'UTR	novel		0.52
CESC	chr8	13023611	3'UTR	novel		0.33
CESC	chr8	13026082	3'UTR	novel		0.63
CESC	chr8	13027404	3'UTR	novel		0.39
CHOL	chr8	13023251	3'UTR	novel		0.52
CHOL	chr8	13025659	3'UTR	novel		0.58
COAD	chr8	13021347	Missense_Mutation	NA	R223I	0.38
COAD	chr8	13023187	3'UTR	novel		0.34
COAD	chr8	13023881	3'UTR	novel		0.38
COAD	chr8	13026067	3'UTR	novel		0.46
COAD	chr8	13027045	3'UTR	novel		0.32
COAD	chr8	13027538	3'UTR	novel		0.28
COAD	chr8	13029169	3'UTR	novel		0.4
COAD	chr8	13026868	3'UTR	novel		0.08
COAD	chr8	13029402	3'UTR	novel		0.16
COAD	chr8	13026445	3'UTR	novel		0.28
COAD	chr8	13024905	3'UTR	novel		0.41
COAD	chr8	13006347	Missense_Mutation	rs766632690	A49T	0.35	Methyltransf_31
COAD	chr8	13024785	3'UTR	novel		0.21
COAD	chr8	13024321	3'UTR	novel		0.27
COAD	chr8	13026335	3'UTR	novel		0.26
COAD	chr8	13006319	Silent	novel	L39L	0.21
COAD	chr8	13024803	3'UTR	novel		0.27
COAD	chr8	13022566	3'UTR	novel		0.39
COAD	chr8	13027864	3'UTR	novel		0.09
COAD	chr8	13027979	3'UTR	novel		0.52
COAD	chr8	13026458	3'UTR	novel		0.83
COAD	chr8	13026458	3'UTR	novel		0.47
COAD	chr8	13028751	3'UTR	novel		0.43
COAD	chr8	13026255	3'UTR	novel		0.4
COAD	chr8	13026458	3'UTR	novel		0.5
COAD	chr8	13028183	3'UTR	novel		0.29
COAD	chr8	13023988	3'UTR	NA		0.4
COAD	chr8	13026458	3'UTR	novel		0.25
COAD	chr8	13028416	3'UTR	novel		0.48
COAD	chr8	13028101	3'UTR	novel		0.68
COAD	chr8	13024912	3'UTR	rs572176860		0.67
COAD	chr8	13021165	Silent	NA	R162R	0.36
COAD	chr8	13023934	3'UTR	novel		0.31
COAD	chr8	13024042	3'UTR	novel		0.38
COAD	chr8	13028751	3'UTR	novel		0.39
COAD	chr8	13029054	3'UTR	NA		0.11
COAD	chr8	13024895	3'UTR	novel		0.42
COAD	chr8	13026538	3'UTR	novel		0.13
COAD	chr8	13027155	3'UTR	novel		0.13
COAD	chr8	13023906	3'UTR	novel		0.2
COAD	chr8	13006256	Missense_Mutation	NA	E18D	0.13
COAD	chr8	13012767	Missense_Mutation	NA	A80T	0.22	Methyltransf_31
COAD	chr8	13028751	3'UTR	novel		0.3
COAD	chr8	13024905	3'UTR	novel		0.11
COAD	chr8	13026838	3'UTR	novel		0.48
COAD	chr8	13028751	3'UTR	novel		0.33
COAD	chr8	13021359	Missense_Mutation	rs761173357	A227V	0.26
COAD	chr8	13025551	3'UTR	novel		0.29
COAD	chr8	13029037	3'UTR	novel		0.43
COAD	chr8	13023226	3'UTR	novel		0.09
COAD	chr8	13023809	3'UTR	novel		0.13
COAD	chr8	13025673	3'UTR	novel		0.13
COAD	chr8	13026023	3'UTR	novel		0.34
COAD	chr8	13028855	3'UTR	novel		0.16
COAD	chr8	13026458	3'UTR	novel		0.61
COAD	chr8	13022798	3'UTR	novel		0.45
COAD	chr8	13025681	3'UTR	novel		0.26
COAD	chr8	13025927	3'UTR	rs529919718		0.28
COAD	chr8	13026638	3'UTR	novel		0.07
COAD	chr8	13021896	Missense_Mutation	rs758134647	T406I	0.26
COAD	chr8	13022743	3'UTR	novel		0.29
COAD	chr8	13024912	3'UTR	rs572176860		0.11
COAD	chr8	13028751	3'UTR	novel		0.43
COAD	chr8	13024083	3'UTR	novel		0.64
COAD	chr8	13023106	3'UTR	novel		0.33
COAD	chr8	13027155	3'UTR	novel		0.28
COAD	chr8	13029501	3'UTR	novel		0.28
COAD	chr8	13026458	3'UTR	novel		0.22
COAD	chr8	13006308	Missense_Mutation	rs773953427	R36C	0.4	Methyltransf_31
COAD	chr8	13024345	3'UTR	novel		0.15
COAD	chr8	13024793	3'UTR	novel		0.18
COAD	chr8	13028439	3'UTR	novel		0.17
COAD	chr8	13025417	3'UTR	novel		0.24
COAD	chr8	13026457	3'UTR	novel		0.31
COAD	chr8	13029392	3'UTR	novel		0.33
COAD	chr8	13026458	3'UTR	novel		0.32
COAD	chr8	13026796	3'UTR	novel		0.06
COAD	chr8	13028751	3'UTR	novel		0.27
COAD	chr8	13022315	3'UTR	novel		0.31
DLBC	chr8	13025385	3'UTR	rs554349574		0.47
DLBC	chr8	13024201	3'UTR	novel		0.3
ESCA	chr8	13022391	3'UTR	novel		0.59
ESCA	chr8	13023762	3'UTR	novel		0.3
ESCA	chr8	13022466	3'UTR	novel		0.48
ESCA	chr8	13026990	3'UTR	novel		0.19
ESCA	chr8	13028919	3'UTR	novel		0.72
ESCA	chr8	13021459	Silent	novel	T260T	0.36
ESCA	chr8	13025621	3'UTR	novel		0.4
ESCA	chr8	13021373	Missense_Mutation	novel	E232K	0.22
ESCA	chr8	13022637	3'UTR	novel		0.4
GBM	chr8	13021310	Missense_Mutation	rs753205236	R211W	0.11
HNSC	chr8	13021421	Missense_Mutation	novel	R248S	0.22
HNSC	chr8	13012829	Missense_Mutation	novel	E100D	0.42	Methyltransf_31
HNSC	chr8	13021297	Silent	novel	Q206Q	0.08
HNSC	chr8	13012790	Silent	novel	A87A	0.4
HNSC	chr8	13021069	Silent	rs543130685	V130V	0.13
KICH	chr8	13026422	3'UTR	novel		0.1
KICH	chr8	13022594	3'UTR	novel		0.06
KIRC	chr8	13021644	Missense_Mutation	rs764700281	E322G	0.4
KIRC	chr8	13022033	Missense_Mutation	NA	G452R	0.2
KIRC	chr8	13012704	Frame_Shift_Del	novel	*L59Kfs2**	0.19	Methyltransf_31
KIRP	chr8	13028000	3'UTR	novel		0.44
KIRP	chr8	13021549	Silent	NA	S290S	0.24
KIRP	chr8	13024423	3'UTR	novel		0.38
KIRP	chr8	13025106	3'UTR	novel		0.4
KIRP	chr8	13027365	3'UTR	novel		0.36
KIRP	chr8	13024039	3'UTR	novel		0.29
LGG	chr8	13006218	Missense_Mutation	rs192500625	A6T	0.35
LIHC	chr8	13021842	Missense_Mutation	novel	N388S	0.32
LIHC	chr8	13021519	Missense_Mutation	NA	S280R	0.31
LIHC	chr8	13027790	3'UTR	novel		0.83
LIHC	chr8	13023472	3'UTR	novel		0.09
LIHC	chr8	13024222	3'UTR	novel		1
LIHC	chr8	13023946	3'UTR	novel		0.22
LUAD	chr8	13012749	Missense_Mutation	novel	G74W	0.14	Methyltransf_31
LUAD	chr8	13021716	Missense_Mutation	NA	G346V	0.54
LUAD	chr8	13021497	Missense_Mutation	rs758376419	N273S	0.27
LUAD	chr8	13021368	Missense_Mutation	novel	S230Y	0.09
LUAD	chr8	13021231	Silent	novel	P184P	0.12
LUAD	chr8	13021826	Missense_Mutation	rs570175321	D383N	0.29
LUSC	chr8	13012589	Intron	novel		0.59
LUSC	chr8	13021516	Silent	rs201315040	S279S	0.38
LUSC	chr8	13021481	Missense_Mutation	NA	V268I	0.24
LUSC	chr8	13012761	Missense_Mutation	rs778807979	E78Q	0.43	Methyltransf_31
LUSC	chr8	13006239	Missense_Mutation	novel	V13L	0.32
LUSC	chr8	13021253	Missense_Mutation	NA	P192S	0.29
OV	chr8	13021904	Missense_Mutation	novel	M409L	0.45
OV	chr8	13021890	Missense_Mutation	novel	D404V	0.09
OV	chr8	13021305	Missense_Mutation	novel	S209L	0.47
OV	chr8	13021417	Silent	novel	S246S	0.09
PRAD	chr8	13012768	Missense_Mutation	novel	A80V	0.06	Methyltransf_31
READ	chr8	13022476	3'UTR	novel		0.22
READ	chr8	13024913	3'UTR	novel		0.28
READ	chr8	13025926	3'UTR	novel		0.38
READ	chr8	13024977	3'UTR	novel		0.16
READ	chr8	13029249	3'UTR	novel		0.1
READ	chr8	13023739	3'UTR	novel		0.27
READ	chr8	13025653	3'UTR	novel		0.16
READ	chr8	13026980	3'UTR	novel		0.27
READ	chr8	13028535	3'UTR	novel		0.3
SARC	chr8	13021887	Missense_Mutation	novel	L403S	0.38
SARC	chr8	12990967	5'UTR	novel		0.85
SARC	chr8	13029625	3'UTR	novel		0.07
SKCM	chr8	13021787	Missense_Mutation	NA	P370S	0.68
SKCM	chr8	13012840	Missense_Mutation	novel	A104V	0.38	Methyltransf_31
SKCM	chr8	13021421	Missense_Mutation	rs192687145	R248C	0.44
SKCM	chr8	13012756	Missense_Mutation	NA	L76Q	0.23	Methyltransf_31
SKCM	chr8	13022046	3'UTR	novel		0.38
SKCM	chr8	13022047	3'UTR	novel		0.39
SKCM	chr8	13021535	Missense_Mutation	novel	P286S	0.1
SKCM	chr8	13021209	Missense_Mutation	novel	R177K	0.37
SKCM	chr8	13021210	Silent	rs764899261	R177R	0.37
SKCM	chr8	13012644	Intron	novel		0.44
SKCM	chr8	13021421	Missense_Mutation	rs192687145	R248C	0.31
SKCM	chr8	13012690	Missense_Mutation	NA	G54E	0.14	Methyltransf_31
SKCM	chr8	13021409	Missense_Mutation	NA	G244R	0.24
STAD	chr8	13021830	Missense_Mutation	novel	S384Y	0.12
STAD	chr8	13021690	Silent	novel	H337H	0.24
STAD	chr8	13021327	Silent	NA	G216G	0.37
STAD	chr8	13021127	Missense_Mutation	rs750803184	H150Y	0.31
STAD	chr8	13021422	Missense_Mutation	rs184909958	R248H	0.08
STAD	chr8	13012638	Intron	novel		0.35
STAD	chr8	13021422	Missense_Mutation	rs184909958	R248H	0.15
UCEC	chr8	13022087	3'UTR	novel		0.38
UCEC	chr8	13022387	3'UTR	novel		0.27
UCEC	chr8	13028253	3'UTR	novel		0.14
UCEC	chr8	13012577	Intron	novel		0.27
UCEC	chr8	13006260	Missense_Mutation	novel	T20A	0.35
UCEC	chr8	13021120	Missense_Mutation	novel	K147N	0.38
UCEC	chr8	13021829	Missense_Mutation	novel	S384P	0.65
UCEC	chr8	13023838	3'UTR	novel		0.42
UCEC	chr8	13023698	3'UTR	novel		0.41
UCEC	chr8	13021344	Missense_Mutation	novel	A222V	0.46
UCEC	chr8	13029310	3'UTR	novel		0.17
UCEC	chr8	13021124	Missense_Mutation	rs757522197	R149C	0.42
UCEC	chr8	13022315	3'UTR	novel		0.42
UCEC	chr8	13023866	3'UTR	novel		0.46
UCEC	chr8	13024694	3'UTR	novel		0.29
UCEC	chr8	13026580	3'UTR	novel		0.39
UCEC	chr8	13026955	3'UTR	novel		0.43
UCEC	chr8	13022693	3'UTR	novel		0.38
UCEC	chr8	13023754	3'UTR	novel		0.14
UCEC	chr8	13024428	3'UTR	novel		0.35
UCEC	chr8	13028227	3'UTR	novel		0.55
UCEC	chr8	13012704	Missense_Mutation	NA	L59F	0.26	Methyltransf_31
UCEC	chr8	13012836	Missense_Mutation	rs770252864	D103N	0.17	Methyltransf_31
UCEC	chr8	13021864	Silent	rs769911796	V395V	0.24
UCEC	chr8	13025980	3'UTR	rs540725605		0.78
UCEC	chr8	13012683	Splice_Site	rs757868573	X52_splice	0.21
UCEC	chr8	13029054	3'UTR	NA		0.12
UCEC	chr8	13012610	Intron	novel		0.54
UCEC	chr8	13026189	3'UTR	novel		0.25
UCEC	chr8	13026931	3'UTR	novel		0.58
UCEC	chr8	13012730	Silent	rs764475691	T67T	0.26
UCEC	chr8	13021907	Missense_Mutation	rs368311524	R410C	0.27
UCEC	chr8	13026569	3'UTR	novel		0.15
UCEC	chr8	13025927	3'UTR	rs529919718		0.38
UCEC	chr8	13027096	3'UTR	novel		0.29
UCEC	chr8	12990882	5'UTR	novel		0.08
UCEC	chr8	13021055	Nonsense_Mutation	rs767656604	E126*	0.44	Methyltransf_31
UCEC	chr8	13021294	Missense_Mutation	novel	E205D	0.55
UCEC	chr8	13021826	Missense_Mutation	rs570175321	D383N	0.5
UCEC	chr8	13025811	3'UTR	novel		0.3
UCEC	chr8	13025982	3'UTR	novel		0.38
UCEC	chr8	13026170	3'UTR	novel		0.63
UCEC	chr8	13027888	3'UTR	novel		0.17
UCEC	chr8	12991017	5'UTR	novel		0.24
UCEC	chr8	13006346	Silent	rs763032257	I48I	0.4
UCEC	chr8	13026544	3'UTR	novel		0.17
UCEC	chr8	13026738	3'UTR	novel		0.53
UCEC	chr8	13026979	3'UTR	NA		0.4
UCEC	chr8	13027974	3'UTR	novel		0.56
UCEC	chr8	13028171	3'UTR	novel		0.29
UCEC	chr8	13026078	3'UTR	novel		0.19
UCEC	chr8	13029624	3'UTR	novel		0.13
UCEC	chr8	13026569	3'UTR	novel		0.32
UCEC	chr8	13021366	Missense_Mutation	novel	I229M	0.4
UCEC	chr8	13027216	3'UTR	novel		0.1
UCEC	chr8	13027581	3'UTR	novel		0.3
UCEC	chr8	13027816	3'UTR	novel		0.47
UCEC	chr8	13021865	Missense_Mutation	NA	E396K	0.05
UCEC	chr8	13022383	3'UTR	novel		0.34
UCEC	chr8	13023480	3'UTR	novel		0.28
UCEC	chr8	13021378	Silent	rs375295510	G233G	0.56
UCEC	chr8	13023769	3'UTR	novel		0.69
UCEC	chr8	13028399	3'UTR	novel		0.33
UCEC	chr8	13028850	3'UTR	novel		0.35
UCEC	chr8	13012836	Missense_Mutation	rs770252864	D103N	0.41	Methyltransf_31
UCEC	chr8	13021347	Missense_Mutation	NA	R223I	0.45
UCEC	chr8	13026773	3'UTR	novel		0.42
UCEC	chr8	13028750	3'UTR	novel		0.17
UCEC	chr8	13026197	3'UTR	novel		0.63
UCEC	chr8	13027238	3'UTR	novel		0.71
UCEC	chr8	13028069	3'UTR	rs548022439		0.6
UCEC	chr8	13029451	3'UTR	novel		0.11
UCEC	chr8	13024774	3'UTR	novel		0.18
UCEC	chr8	13024268	3'UTR	novel		0.22
UCEC	chr8	13025064	3'UTR	novel		0.24
UCEC	chr8	13027680	3'UTR	novel		0.17
UCEC	chr8	13029004	3'UTR	novel		0.18
UCEC	chr8	13028751	3'UTR	novel		0.5
UCEC	chr8	13022357	3'UTR	novel		0.24
UCEC	chr8	13025862	3'UTR	novel		0.33
UCEC	chr8	13027644	3'UTR	novel		0.26
UCEC	chr8	13025980	3'UTR	rs540725605		0.48
UCEC	chr8	13012611	Intron	novel		0.58
UCEC	chr8	13022332	3'UTR	novel		0.11
UCEC	chr8	13025927	3'UTR	rs529919718		0.36
UCEC	chr8	13026931	3'UTR	novel		0.38
UCEC	chr8	13027697	3'UTR	novel		0.31
UCEC	chr8	13029645	3'UTR	novel		0.31
UCEC	chr8	13029056	3'UTR	novel		0.51
UCEC	chr8	13025712	3'UTR	rs369147436		0.17
UCEC	chr8	13021416	Missense_Mutation	rs760934307	S246L	0.32
UCEC	chr8	13025060	3'UTR	novel		0.22
UCEC	chr8	13027437	3'UTR	rs749552810		0.5
UCEC	chr8	13029250	3'UTR	novel		0.58
UCEC	chr8	13029392	3'UTR	novel		0.43
UCEC	chr8	13021145	Missense_Mutation	novel	V156M	0.49
UCEC	chr8	13021144	Missense_Mutation	rs748847588	D155E	0.12
UCEC	chr8	13024643	3'UTR	novel		0.07
UCEC	chr8	13027112	3'UTR	novel		0.27
UCEC	chr8	13027277	3'UTR	novel		0.15
UCEC	chr8	13029037	3'UTR	novel		0.11
UCEC	chr8	13022697	3'UTR	novel		0.52
UCEC	chr8	13025732	3'UTR	novel		0.23
UCEC	chr8	13028201	3'UTR	novel		0.18
UCEC	chr8	13024301	3'UTR	novel		0.29
UCEC	chr8	13028751	3'UTR	novel		0.45
UCEC	chr8	13021144	Silent	rs748847588	D155D	0.15
UCEC	chr8	13025665	3'UTR	novel		0.2
UCEC	chr8	13026086	3'UTR	novel		0.4
UCEC	chr8	13026366	3'UTR	novel		0.27
UCEC	chr8	13027162	3'UTR	novel		0.2
UCEC	chr8	13023120	3'UTR	novel		0.35
UCEC	chr8	13026947	3'UTR	novel		0.31
UCEC	chr8	13027826	3'UTR	novel		0.45
UCEC	chr8	13029428	3'UTR	novel		0.24
UCEC	chr8	13025960	3'UTR	novel		0.35
UCEC	chr8	13021129	Missense_Mutation	NA	H150Q	0.38
UCEC	chr8	13023825	3'UTR	novel		0.2
UCEC	chr8	13025143	3'UTR	novel		0.33
UCEC	chr8	13025532	3'UTR	novel		0.21
UCEC	chr8	13027709	3'UTR	novel		0.39
UCEC	chr8	13021125	Missense_Mutation	rs779088518	R149H	0.16
UCEC	chr8	13012835	Silent	rs147161360	F102F	0.36
UCEC	chr8	13021035	Missense_Mutation	novel	R119I	0.22	Methyltransf_31
UCEC	chr8	13023666	3'UTR	novel		0.41
UCEC	chr8	13029159	3'UTR	novel		0.5
UCEC	chr8	13025040	3'UTR	novel		0.26
UCEC	chr8	13025980	3'UTR	rs540725605		0.49
UCEC	chr8	13021292	Nonsense_Mutation	novel	E205*	0.29
UCEC	chr8	13022023	Missense_Mutation	novel	E448D	0.33
UCEC	chr8	13027574	3'UTR	novel		0.28
UCEC	chr8	13021207	Silent	novel	G176G	0.34
UCEC	chr8	13022213	3'UTR	novel		0.28
UCEC	chr8	13029131	3'UTR	novel		0.38
UCS	chr8	13021347	Missense_Mutation	novel	R223K	0.27

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	DEL	0.549	4.5185e-08
DLBC	DEL	0.2292	0.15679
PAAD	DEL	0.2391	0.050455
READ	DEL	0.5697	0.20625
UCS	DEL	0.5179	0.0031922

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.003	Kaplan-Meier Survival Analysis
MESO	0.039	Kaplan-Meier Survival Analysis
HNSC	0.0082	Kaplan-Meier Survival Analysis
LUSC	0.0061	Kaplan-Meier Survival Analysis
BRCA	0.0069	Kaplan-Meier Survival Analysis
KIRP	0.00041	Kaplan-Meier Survival Analysis
COAD	0.0027	Kaplan-Meier Survival Analysis
PAAD	0.023	Kaplan-Meier Survival Analysis
UCEC	0.017	Kaplan-Meier Survival Analysis
LGG	0.0074	Kaplan-Meier Survival Analysis
THCA	0.036	Kaplan-Meier Survival Analysis
LUAD	0.018	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742