EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000251369 (Gene tree)
Gene ID: 162972
Gene Symbol: ZNF550
Alias: MGC41917
Full Name: zinc finger protein 550
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 26,391 bases
Position: chr19:57,535,257-57,561,647
Accession: 28643
RBP type: canonical RBP
Summary: ZNF550 (Zinc Finger Protein 550) is a Protein Coding gene. Among its related pathways are Gene Expression and Herpes simplex virus 1 infection. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF599.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000445978	zf-C2H2	PF00096.26	4.2e-37	1	7
ENSP00000445978	zf-C2H2	PF00096.26	4.2e-37	2	7
ENSP00000445978	zf-C2H2	PF00096.26	4.2e-37	3	7
ENSP00000445978	zf-C2H2	PF00096.26	4.2e-37	4	7
ENSP00000445978	zf-C2H2	PF00096.26	4.2e-37	5	7
ENSP00000445978	zf-C2H2	PF00096.26	4.2e-37	6	7
ENSP00000445978	zf-C2H2	PF00096.26	4.2e-37	7	7
ENSP00000422344	zf-C2H2	PF00096.26	1.2e-36	1	6
ENSP00000422344	zf-C2H2	PF00096.26	1.2e-36	2	6
ENSP00000422344	zf-C2H2	PF00096.26	1.2e-36	3	6
ENSP00000422344	zf-C2H2	PF00096.26	1.2e-36	4	6
ENSP00000422344	zf-C2H2	PF00096.26	1.2e-36	5	6
ENSP00000422344	zf-C2H2	PF00096.26	1.2e-36	6	6
ENSP00000446224	zf-C2H2	PF00096.26	3e-36	1	6
ENSP00000446224	zf-C2H2	PF00096.26	3e-36	2	6
ENSP00000446224	zf-C2H2	PF00096.26	3e-36	3	6
ENSP00000446224	zf-C2H2	PF00096.26	3e-36	4	6
ENSP00000446224	zf-C2H2	PF00096.26	3e-36	5	6
ENSP00000446224	zf-C2H2	PF00096.26	3e-36	6	6
ENSP00000469679	zf-C2H2	PF00096.26	3e-36	1	6
ENSP00000469679	zf-C2H2	PF00096.26	3e-36	2	6
ENSP00000469679	zf-C2H2	PF00096.26	3e-36	3	6
ENSP00000469679	zf-C2H2	PF00096.26	3e-36	4	6
ENSP00000469679	zf-C2H2	PF00096.26	3e-36	5	6
ENSP00000469679	zf-C2H2	PF00096.26	3e-36	6	6
ENSP00000422344	zf-met	PF12874.7	0.00092	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000376230	ZNF550-203	3719	-	ENSP00000469537	422 (aa)	-	Q7Z398
ENST00000595560	ZNF550-207	565	-	-	- (aa)	-	-
ENST00000447310	ZNF550-204	4305	-	ENSP00000469580	422 (aa)	-	Q7Z398
ENST00000344222	ZNF550-202	3485	-	ENSP00000445978	339 (aa)	-	M0QWZ8
ENST00000506609	ZNF550-206	1361	-	ENSP00000422344	381 (aa)	-	A0A0C4DGB4
ENST00000601415	ZNF550-208	515	-	ENSP00000472973	125 (aa)	-	M0R337
ENST00000325134	ZNF550-201	4305	XM_011526567	ENSP00000446224	422 (aa)	XP_011524869	Q7Z398
ENST00000457177	ZNF550-205	3376	-	ENSP00000469679	422 (aa)	-	Q7Z398

Gene Model

Click here to download ENSG00000251369's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa05168	Herpes simplex virus 1 infection	KEGG

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000251369	rs1548476	19	57547168	A	Male-pattern baldness	30573740	[0.012-0.024] unit increase	0.0178925	EFO_0007825

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000251369's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000251369	ZNF550	100	95.801	ENSCATG00000020915	ZNF550	100	95.801	Cercocebus_atys
ENSG00000251369	ZNF550	99	70.118	ENSCLAG00000000250	ZNF550	95	68.800	Chinchilla_lanigera
ENSG00000251369	ZNF550	99	94.675	ENSCSAG00000001629	ZNF550	100	94.673	Chlorocebus_sabaeus
ENSG00000251369	ZNF550	100	95.276	ENSCANG00000033735	ZNF550	100	95.276	Colobus_angolensis_palliatus
ENSG00000251369	ZNF550	99	72.941	ENSDNOG00000033330	-	99	71.229	Dasypus_novemcinctus
ENSG00000251369	ZNF550	99	70.604	ENSFCAG00000034766	ZNF550	99	70.604	Felis_catus
ENSG00000251369	ZNF550	100	99.526	ENSGGOG00000014068	ZNF550	100	99.526	Gorilla_gorilla
ENSG00000251369	ZNF550	100	71.698	ENSHGLG00000018048	ZNF550	100	71.698	Heterocephalus_glaber_female
ENSG00000251369	ZNF550	100	95.276	ENSMFAG00000036005	ZNF550	100	95.276	Macaca_fascicularis
ENSG00000251369	ZNF550	100	95.013	ENSMMUG00000006122	ZNF550	100	95.013	Macaca_mulatta
ENSG00000251369	ZNF550	100	95.276	ENSMNEG00000041366	ZNF550	100	95.276	Macaca_nemestrina
ENSG00000251369	ZNF550	100	95.538	ENSMLEG00000034688	ZNF550	100	95.538	Mandrillus_leucophaeus
ENSG00000251369	ZNF550	100	85.079	ENSMICG00000007561	ZNF550	100	85.079	Microcebus_murinus
ENSG00000251369	ZNF550	99	70.341	ENSPPRG00000013475	ZNF550	99	70.341	Panthera_pardus
ENSG00000251369	ZNF550	100	69.868	ENSPTIG00000018007	ZNF550	80	69.162	Panthera_tigris_altaica
ENSG00000251369	ZNF550	100	99.526	ENSPTRG00000011560	ZNF550	100	99.526	Pan_troglodytes
ENSG00000251369	ZNF550	100	95.013	ENSPANG00000030602	ZNF550	100	95.013	Papio_anubis
ENSG00000251369	ZNF550	100	87.173	ENSPCOG00000018751	ZNF550	100	87.173	Propithecus_coquereli
ENSG00000251369	ZNF550	99	71.496	ENSPVAG00000000908	ZNF550	100	71.734	Pteropus_vampyrus
ENSG00000251369	ZNF550	100	96.325	ENSRBIG00000017275	ZNF550	100	96.325	Rhinopithecus_bieti
ENSG00000251369	ZNF550	100	96.325	ENSRROG00000040063	ZNF550	100	96.325	Rhinopithecus_roxellana
ENSG00000251369	ZNF550	99	80.531	ENSTTRG00000000293	ZNF550	100	80.435	Tursiops_truncatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0005515	protein binding	25416956.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0046872	metal ion binding	-	IEA	Function