EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000254772 (Gene tree)
Gene ID: 1937
Gene Symbol: EEF1G
Alias: EF1G
Full Name: eukaryotic translation elongation factor 1 gamma
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 14,486 bases
Position: chr11:62,559,601-62,574,086
Accession: 3213
RBP type: canonical RBP
Summary: This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000331901	EF1G	PF00647.19	3.9e-52	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
1869528	A major substrate of maturation promoting factor identified as elongation factor 1 beta gamma delta in Xenopus laevis.	J Biol Chem	1991 Aug 15	Janssen GM	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000525340	EEF1G-203	2496	-	-	- (aa)	-	-
ENST00000329251	EEF1G-201	1523	-	ENSP00000331901	437 (aa)	-	P26641
ENST00000524420	EEF1G-202	557	-	-	- (aa)	-	-
ENST00000532986	EEF1G-204	578	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000254772's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa05134	Legionellosis	KEGG

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000254772	rs1061093	11	62567436	C	Waist-to-hip ratio adjusted for BMI	26426971	units increase	0.023226092	EFO_0007788
ENSG00000254772	rs7943191	11	62561079	G	Waist-to-hip ratio adjusted for body mass index	28448500	[0.017-0.041] unit increase	0.029	EFO_0007788\|EFO_0008002
ENSG00000254772	rs7943191	11	62561079	G	Waist-to-hip ratio adjusted for body mass index	28448500	[0.017-0.036] unit increase	0.0266	EFO_0007788\|EFO_0008002
ENSG00000254772	rs7943191	11	62561079	G	Waist-to-hip ratio adjusted for body mass index	28448500	[0.016-0.034] unit increase	0.0253	EFO_0007788\|EFO_0008002
ENSG00000254772	rs7943191	11	62561079	G	Waist-to-hip ratio adjusted for BMI in active individuals	28448500	[0.015-0.036] unit increase	0.0252	EFO_0007788\|EFO_0008002
ENSG00000254772	rs7943191	11	62561079	G	Waist-to-hip ratio adjusted for BMI in active individuals	28448500	[0.015-0.036] unit increase	0.0252	EFO_0007788\|EFO_0008002
ENSG00000254772	rs7943191	11	62561079	?	Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction)	28448500			EFO_0007788\|EFO_0008002
ENSG00000254772	rs7943191	11	62561079	?	Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction)	28448500			EFO_0007788\|EFO_0008002
ENSG00000254772	rs7943191	11	62561079	?	Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction)	28448500			EFO_0007788\|EFO_0008002
ENSG00000254772	rs1061093	11	62567436	C	Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	26426971			EFO_0007788\|EFO_0008343\|EFO_0008007

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000254772's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000254772	EEF1G	57	34.231	ENSG00000204394	VARS	96	34.270

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000254772	EEF1G	100	75.973	ENSAPOG00000011000	eef1g	100	76.484	Acanthochromis_polyacanthus
ENSG00000254772	EEF1G	100	98.409	ENSAMEG00000006745	-	100	98.409	Ailuropoda_melanoleuca
ENSG00000254772	EEF1G	100	75.283	ENSACIG00000007271	eef1g	100	75.901	Amphilophus_citrinellus
ENSG00000254772	EEF1G	100	75.286	ENSAOCG00000000857	eef1g	100	75.799	Amphiprion_ocellaris
ENSG00000254772	EEF1G	100	75.286	ENSAPEG00000011179	eef1g	100	75.799	Amphiprion_percula
ENSG00000254772	EEF1G	100	75.744	ENSATEG00000013408	eef1g	100	75.744	Anabas_testudineus
ENSG00000254772	EEF1G	98	76.923	ENSANAG00000023051	-	98	77.389	Aotus_nancymaae
ENSG00000254772	EEF1G	100	84.439	ENSANAG00000024873	-	100	84.439	Aotus_nancymaae
ENSG00000254772	EEF1G	100	80.092	ENSANAG00000006625	-	100	80.092	Aotus_nancymaae
ENSG00000254772	EEF1G	100	75.964	ENSACLG00000014785	eef1g	100	76.577	Astatotilapia_calliptera
ENSG00000254772	EEF1G	100	74.603	ENSAMXG00000040220	eef1g	100	76.244	Astyanax_mexicanus
ENSG00000254772	EEF1G	100	97.955	ENSBTAG00000011843	EEF1G	100	97.955	Bos_taurus
ENSG00000254772	EEF1G	99	45.642	WBGene00008920	eef-1G	99	46.911	Caenorhabditis_elegans
ENSG00000254772	EEF1G	100	99.085	ENSCJAG00000018949	EEF1G	100	99.085	Callithrix_jacchus
ENSG00000254772	EEF1G	95	94.686	ENSCJAG00000041183	-	97	94.686	Callithrix_jacchus
ENSG00000254772	EEF1G	100	86.728	ENSCAFG00000024643	-	100	86.728	Canis_familiaris
ENSG00000254772	EEF1G	100	89.474	ENSCAFG00000007791	-	100	89.474	Canis_familiaris
ENSG00000254772	EEF1G	100	98.398	ENSCAFG00000015834	-	100	98.398	Canis_familiaris
ENSG00000254772	EEF1G	99	94.495	ENSCAFG00000017325	-	99	94.495	Canis_familiaris
ENSG00000254772	EEF1G	100	96.796	ENSCAFG00020022536	-	100	96.796	Canis_lupus_dingo
ENSG00000254772	EEF1G	71	77.885	ENSCAFG00020013031	EEF1G	98	77.885	Canis_lupus_dingo
ENSG00000254772	EEF1G	100	81.136	ENSCHIG00000018951	-	100	81.818	Capra_hircus
ENSG00000254772	EEF1G	100	97.727	ENSCHIG00000022487	-	100	97.727	Capra_hircus
ENSG00000254772	EEF1G	100	97.941	ENSTSYG00000000144	-	100	97.941	Carlito_syrichta
ENSG00000254772	EEF1G	73	81.040	ENSTSYG00000027201	-	100	81.040	Carlito_syrichta
ENSG00000254772	EEF1G	100	89.703	ENSTSYG00000026971	-	100	89.703	Carlito_syrichta
ENSG00000254772	EEF1G	89	76.982	ENSTSYG00000032549	-	99	76.982	Carlito_syrichta
ENSG00000254772	EEF1G	99	70.183	ENSTSYG00000037581	-	99	70.183	Carlito_syrichta
ENSG00000254772	EEF1G	73	96.215	ENSCAPG00000000155	-	100	96.215	Cavia_aperea
ENSG00000254772	EEF1G	100	96.568	ENSCPOG00000025703	-	100	96.568	Cavia_porcellus
ENSG00000254772	EEF1G	69	76.821	ENSCCAG00000037846	-	87	76.821	Cebus_capucinus
ENSG00000254772	EEF1G	97	79.858	ENSCCAG00000033143	-	99	79.858	Cebus_capucinus
ENSG00000254772	EEF1G	100	98.856	ENSCCAG00000033526	EEF1G	100	98.856	Cebus_capucinus
ENSG00000254772	EEF1G	100	72.540	ENSCCAG00000019627	-	100	72.540	Cebus_capucinus
ENSG00000254772	EEF1G	100	70.159	ENSCCAG00000018015	-	100	70.159	Cebus_capucinus
ENSG00000254772	EEF1G	100	88.787	ENSCCAG00000028226	-	100	88.787	Cebus_capucinus
ENSG00000254772	EEF1G	100	99.771	ENSCATG00000038495	EEF1G	100	99.771	Cercocebus_atys
ENSG00000254772	EEF1G	100	97.254	ENSCLAG00000000315	-	100	97.254	Chinchilla_lanigera
ENSG00000254772	EEF1G	100	99.542	ENSCSAG00000006560	EEF1G	100	99.542	Chlorocebus_sabaeus
ENSG00000254772	EEF1G	99	81.881	ENSCPBG00000017974	EEF1G	99	83.716	Chrysemys_picta_bellii
ENSG00000254772	EEF1G	99	47.926	ENSCING00000002308	-	99	48.853	Ciona_intestinalis
ENSG00000254772	EEF1G	99	49.541	ENSCSAVG00000010359	-	98	50.229	Ciona_savignyi
ENSG00000254772	EEF1G	100	87.414	ENSCANG00000036288	-	100	87.414	Colobus_angolensis_palliatus
ENSG00000254772	EEF1G	100	84.439	ENSCANG00000033826	-	100	84.439	Colobus_angolensis_palliatus
ENSG00000254772	EEF1G	100	89.703	ENSCANG00000043393	EEF1G	100	89.703	Colobus_angolensis_palliatus
ENSG00000254772	EEF1G	87	70.419	ENSCGRG00001011707	-	97	74.607	Cricetulus_griseus_chok1gshd
ENSG00000254772	EEF1G	100	97.941	ENSCGRG00001013631	Eef1g	100	97.941	Cricetulus_griseus_chok1gshd
ENSG00000254772	EEF1G	100	97.712	ENSCGRG00000014628	Eef1g	100	97.712	Cricetulus_griseus_crigri
ENSG00000254772	EEF1G	99	68.822	ENSCGRG00000014006	-	100	69.746	Cricetulus_griseus_crigri
ENSG00000254772	EEF1G	100	73.243	ENSCSEG00000012081	eef1g	100	75.450	Cynoglossus_semilaevis
ENSG00000254772	EEF1G	95	74.699	ENSCVAG00000021121	eef1g	100	74.699	Cyprinodon_variegatus
ENSG00000254772	EEF1G	100	74.434	ENSDARG00000056119	eef1g	100	82.407	Danio_rerio
ENSG00000254772	EEF1G	100	98.398	ENSDNOG00000031798	-	100	98.398	Dasypus_novemcinctus
ENSG00000254772	EEF1G	100	71.625	ENSDNOG00000046053	-	100	71.625	Dasypus_novemcinctus
ENSG00000254772	EEF1G	100	57.306	FBgn0029176	eEF1gamma	100	57.955	Drosophila_melanogaster
ENSG00000254772	EEF1G	88	69.792	ENSEBUG00000015009	eef1g	90	70.649	Eptatretus_burgeri
ENSG00000254772	EEF1G	100	89.842	ENSEASG00005007513	EEF1G	100	89.842	Equus_asinus_asinus
ENSG00000254772	EEF1G	100	99.314	ENSECAG00000014334	EEF1G	91	99.314	Equus_caballus
ENSG00000254772	EEF1G	81	96.910	ENSEEUG00000001231	EEF1G	100	96.910	Erinaceus_europaeus
ENSG00000254772	EEF1G	100	74.157	ENSELUG00000003429	eef1g	100	75.112	Esox_lucius
ENSG00000254772	EEF1G	100	99.314	ENSFCAG00000008858	EEF1G	100	99.314	Felis_catus
ENSG00000254772	EEF1G	93	63.300	ENSFALG00000011535	EEF1G	98	63.614	Ficedula_albicollis
ENSG00000254772	EEF1G	100	96.796	ENSFDAG00000010506	-	100	96.796	Fukomys_damarensis
ENSG00000254772	EEF1G	100	94.737	ENSFDAG00000007976	-	100	94.737	Fukomys_damarensis
ENSG00000254772	EEF1G	100	75.057	ENSFHEG00000003042	eef1g	100	75.057	Fundulus_heteroclitus
ENSG00000254772	EEF1G	100	72.374	ENSGMOG00000000548	eef1g	100	72.374	Gadus_morhua
ENSG00000254772	EEF1G	100	74.142	ENSGAFG00000001688	eef1g	100	74.142	Gambusia_affinis
ENSG00000254772	EEF1G	100	73.913	ENSGACG00000017702	eef1g	100	73.913	Gasterosteus_aculeatus
ENSG00000254772	EEF1G	99	82.798	ENSGAGG00000001317	EEF1G	99	84.404	Gopherus_agassizii
ENSG00000254772	EEF1G	100	97.483	ENSGGOG00000042744	-	100	97.483	Gorilla_gorilla
ENSG00000254772	EEF1G	96	79.236	ENSGGOG00000043307	-	100	79.236	Gorilla_gorilla
ENSG00000254772	EEF1G	100	99.771	ENSGGOG00000013557	-	100	99.771	Gorilla_gorilla
ENSG00000254772	EEF1G	100	75.737	ENSHBUG00000011457	eef1g	100	76.351	Haplochromis_burtoni
ENSG00000254772	EEF1G	100	95.881	ENSHGLG00000002602	EEF1G	100	95.881	Heterocephalus_glaber_female
ENSG00000254772	EEF1G	100	95.881	ENSHGLG00100018407	EEF1G	100	95.881	Heterocephalus_glaber_male
ENSG00000254772	EEF1G	100	72.769	ENSHCOG00000009488	eef1g	100	73.227	Hippocampus_comes
ENSG00000254772	EEF1G	100	74.718	ENSIPUG00000000647	eef1g	100	76.180	Ictalurus_punctatus
ENSG00000254772	EEF1G	100	98.627	ENSSTOG00000002851	-	100	98.627	Ictidomys_tridecemlineatus
ENSG00000254772	EEF1G	100	87.872	ENSSTOG00000033703	-	100	87.872	Ictidomys_tridecemlineatus
ENSG00000254772	EEF1G	100	98.398	ENSJJAG00000019511	Eef1g	100	98.398	Jaculus_jaculus
ENSG00000254772	EEF1G	100	75.057	ENSJJAG00000017710	-	100	75.057	Jaculus_jaculus
ENSG00000254772	EEF1G	100	75.973	ENSKMAG00000011008	eef1g	100	75.973	Kryptolebias_marmoratus
ENSG00000254772	EEF1G	100	74.142	ENSLBEG00000001378	eef1g	100	74.142	Labrus_bergylta
ENSG00000254772	EEF1G	99	76.674	ENSLACG00000014700	-	99	79.405	Latimeria_chalumnae
ENSG00000254772	EEF1G	98	59.491	ENSLACG00000017814	-	99	59.954	Latimeria_chalumnae
ENSG00000254772	EEF1G	99	59.353	ENSLOCG00000014527	eef1g	100	58.314	Lepisosteus_oculatus
ENSG00000254772	EEF1G	96	98.571	ENSLAFG00000003339	EEF1G	96	98.571	Loxodonta_africana
ENSG00000254772	EEF1G	100	99.771	ENSMFAG00000007224	-	100	99.771	Macaca_fascicularis
ENSG00000254772	EEF1G	100	94.737	ENSMFAG00000034295	-	100	94.737	Macaca_fascicularis
ENSG00000254772	EEF1G	100	67.963	ENSMFAG00000031536	-	100	67.963	Macaca_fascicularis
ENSG00000254772	EEF1G	100	99.771	ENSMMUG00000006598	EEF1G	100	99.771	Macaca_mulatta
ENSG00000254772	EEF1G	100	88.101	ENSMMUG00000020269	-	100	88.101	Macaca_mulatta
ENSG00000254772	EEF1G	67	73.379	ENSMMUG00000045080	-	100	73.379	Macaca_mulatta
ENSG00000254772	EEF1G	67	75.427	ENSMNEG00000038885	-	100	75.427	Macaca_nemestrina
ENSG00000254772	EEF1G	100	99.771	ENSMNEG00000044626	EEF1G	100	99.771	Macaca_nemestrina
ENSG00000254772	EEF1G	86	94.430	ENSMNEG00000004495	-	97	94.430	Macaca_nemestrina
ENSG00000254772	EEF1G	100	68.421	ENSMNEG00000034791	-	100	68.421	Macaca_nemestrina
ENSG00000254772	EEF1G	67	76.792	ENSMLEG00000007374	-	100	76.792	Mandrillus_leucophaeus
ENSG00000254772	EEF1G	100	99.771	ENSMLEG00000023252	EEF1G	100	99.771	Mandrillus_leucophaeus
ENSG00000254772	EEF1G	100	76.430	ENSMAMG00000001122	eef1g	100	76.430	Mastacembelus_armatus
ENSG00000254772	EEF1G	100	75.964	ENSMZEG00005003633	eef1g	100	76.577	Maylandia_zebra
ENSG00000254772	EEF1G	98	72.093	ENSMAUG00000016675	-	99	72.093	Mesocricetus_auratus
ENSG00000254772	EEF1G	68	91.611	ENSMAUG00000012949	-	100	91.611	Mesocricetus_auratus
ENSG00000254772	EEF1G	100	98.627	ENSMICG00000009834	EEF1G	100	98.627	Microcebus_murinus
ENSG00000254772	EEF1G	100	98.398	ENSMOCG00000019677	Eef1g	100	98.398	Microtus_ochrogaster
ENSG00000254772	EEF1G	100	81.693	ENSMOCG00000012556	-	100	81.693	Microtus_ochrogaster
ENSG00000254772	EEF1G	100	74.429	ENSMMOG00000003099	eef1g	100	74.943	Mola_mola
ENSG00000254772	EEF1G	100	92.009	ENSMODG00000023910	-	100	92.009	Monodelphis_domestica
ENSG00000254772	EEF1G	99	92.857	ENSMODG00000007691	-	99	92.857	Monodelphis_domestica
ENSG00000254772	EEF1G	77	52.226	ENSMODG00000011344	-	99	52.226	Monodelphis_domestica
ENSG00000254772	EEF1G	98	65.581	ENSMODG00000004185	-	99	65.814	Monodelphis_domestica
ENSG00000254772	EEF1G	100	75.973	ENSMALG00000013360	eef1g	100	75.973	Monopterus_albus
ENSG00000254772	EEF1G	100	98.398	MGP_CAROLIEiJ_G0022671	Eef1g	100	98.398	Mus_caroli
ENSG00000254772	EEF1G	100	98.169	ENSMUSG00000071644	Eef1g	100	98.169	Mus_musculus
ENSG00000254772	EEF1G	100	94.508	MGP_PahariEiJ_G0014165	Eef1g	100	94.508	Mus_pahari
ENSG00000254772	EEF1G	99	98.148	MGP_SPRETEiJ_G0023584	Eef1g	98	98.148	Mus_spretus
ENSG00000254772	EEF1G	100	99.085	ENSMPUG00000013942	-	100	99.085	Mustela_putorius_furo
ENSG00000254772	EEF1G	100	95.205	ENSMLUG00000000342	-	100	95.205	Myotis_lucifugus
ENSG00000254772	EEF1G	100	87.643	ENSNGAG00000000678	-	100	87.643	Nannospalax_galili
ENSG00000254772	EEF1G	100	97.254	ENSNGAG00000019856	Eef1g	100	97.254	Nannospalax_galili
ENSG00000254772	EEF1G	100	75.737	ENSNBRG00000003913	eef1g	100	76.351	Neolamprologus_brichardi
ENSG00000254772	EEF1G	100	99.087	ENSNLEG00000003528	EEF1G	100	99.087	Nomascus_leucogenys
ENSG00000254772	EEF1G	87	74.934	ENSNLEG00000028478	-	99	74.934	Nomascus_leucogenys
ENSG00000254772	EEF1G	60	69.962	ENSMEUG00000000867	-	65	69.962	Notamacropus_eugenii
ENSG00000254772	EEF1G	60	95.437	ENSOPRG00000014563	EEF1G	100	95.437	Ochotona_princeps
ENSG00000254772	EEF1G	100	96.110	ENSODEG00000002254	-	100	96.110	Octodon_degus
ENSG00000254772	EEF1G	100	73.227	ENSODEG00000008725	-	96	73.455	Octodon_degus
ENSG00000254772	EEF1G	100	96.110	ENSODEG00000019539	-	100	96.110	Octodon_degus
ENSG00000254772	EEF1G	97	75.234	ENSONIG00000005190	eef1g	100	75.870	Oreochromis_niloticus
ENSG00000254772	EEF1G	92	98.756	ENSOCUG00000020959	-	100	98.756	Oryctolagus_cuniculus
ENSG00000254772	EEF1G	100	75.286	ENSORLG00000003130	eef1g	100	75.286	Oryzias_latipes
ENSG00000254772	EEF1G	100	74.828	ENSORLG00020017761	eef1g	100	74.828	Oryzias_latipes_hni
ENSG00000254772	EEF1G	100	74.828	ENSORLG00015018521	eef1g	100	74.828	Oryzias_latipes_hsok
ENSG00000254772	EEF1G	100	74.828	ENSOMEG00000020060	eef1g	100	74.828	Oryzias_melastigma
ENSG00000254772	EEF1G	100	90.868	ENSOGAG00000000827	EEF1G	100	90.868	Otolemur_garnettii
ENSG00000254772	EEF1G	99	97.706	ENSOARG00000015142	-	78	97.706	Ovis_aries
ENSG00000254772	EEF1G	93	80.988	ENSPPAG00000029376	-	100	80.988	Pan_paniscus
ENSG00000254772	EEF1G	100	99.771	ENSPPAG00000043560	-	100	99.771	Pan_paniscus
ENSG00000254772	EEF1G	100	97.483	ENSPPAG00000007374	-	100	97.483	Pan_paniscus
ENSG00000254772	EEF1G	100	99.314	ENSPPRG00000000804	EEF1G	100	99.314	Panthera_pardus
ENSG00000254772	EEF1G	100	99.314	ENSPTIG00000018752	EEF1G	100	99.314	Panthera_tigris_altaica
ENSG00000254772	EEF1G	93	80.494	ENSPTRG00000043395	-	100	80.494	Pan_troglodytes
ENSG00000254772	EEF1G	100	97.025	ENSPTRG00000039432	-	100	97.025	Pan_troglodytes
ENSG00000254772	EEF1G	100	100.000	ENSPTRG00000003768	EEF1G	100	100.000	Pan_troglodytes
ENSG00000254772	EEF1G	99	91.781	ENSPANG00000003106	EEF1G	99	91.781	Papio_anubis
ENSG00000254772	EEF1G	67	76.109	ENSPANG00000033251	-	100	76.109	Papio_anubis
ENSG00000254772	EEF1G	100	76.749	ENSPKIG00000000945	eef1g	100	77.427	Paramormyrops_kingsleyae
ENSG00000254772	EEF1G	99	82.339	ENSPSIG00000004341	EEF1G	99	84.174	Pelodiscus_sinensis
ENSG00000254772	EEF1G	99	70.642	ENSPMGG00000008459	eef1g	99	72.248	Periophthalmus_magnuspinnatus
ENSG00000254772	EEF1G	100	97.945	ENSPEMG00000004247	-	100	97.945	Peromyscus_maniculatus_bairdii
ENSG00000254772	EEF1G	83	69.337	ENSPMAG00000007383	eef1g	99	70.994	Petromyzon_marinus
ENSG00000254772	EEF1G	100	93.836	ENSPCIG00000017806	EEF1G	100	93.836	Phascolarctos_cinereus
ENSG00000254772	EEF1G	100	66.364	ENSPFOG00000010639	eef1g	100	66.364	Poecilia_formosa
ENSG00000254772	EEF1G	100	74.371	ENSPREG00000016570	eef1g	100	74.371	Poecilia_reticulata
ENSG00000254772	EEF1G	51	100.000	ENSPPYG00000029434	-	95	100.000	Pongo_abelii
ENSG00000254772	EEF1G	100	99.085	ENSPCOG00000015966	EEF1G	100	99.085	Propithecus_coquereli
ENSG00000254772	EEF1G	97	97.636	ENSPVAG00000003440	-	100	97.636	Pteropus_vampyrus
ENSG00000254772	EEF1G	100	75.737	ENSPNYG00000016103	eef1g	100	76.351	Pundamilia_nyererei
ENSG00000254772	EEF1G	100	74.266	ENSPNAG00000025293	eef1g	100	75.955	Pygocentrus_nattereri
ENSG00000254772	EEF1G	100	97.712	ENSRNOG00000020075	Eef1g	100	97.712	Rattus_norvegicus
ENSG00000254772	EEF1G	100	84.211	ENSRBIG00000044514	-	100	84.211	Rhinopithecus_bieti
ENSG00000254772	EEF1G	100	99.542	ENSRBIG00000042208	-	100	99.542	Rhinopithecus_bieti
ENSG00000254772	EEF1G	100	93.364	ENSRROG00000044752	-	100	93.364	Rhinopithecus_roxellana
ENSG00000254772	EEF1G	100	99.771	ENSRROG00000036867	-	100	99.771	Rhinopithecus_roxellana
ENSG00000254772	EEF1G	100	88.558	ENSRROG00000045033	-	100	88.558	Rhinopithecus_roxellana
ENSG00000254772	EEF1G	100	99.542	ENSRROG00000042836	-	100	99.542	Rhinopithecus_roxellana
ENSG00000254772	EEF1G	94	94.297	ENSSBOG00000036095	-	100	94.297	Saimiri_boliviensis_boliviensis
ENSG00000254772	EEF1G	100	98.856	ENSSBOG00000029342	EEF1G	100	98.856	Saimiri_boliviensis_boliviensis
ENSG00000254772	EEF1G	100	71.625	ENSSBOG00000021837	-	100	71.625	Saimiri_boliviensis_boliviensis
ENSG00000254772	EEF1G	74	92.331	ENSSHAG00000003032	-	100	92.331	Sarcophilus_harrisii
ENSG00000254772	EEF1G	71	58.599	ENSSHAG00000011225	-	100	58.599	Sarcophilus_harrisii
ENSG00000254772	EEF1G	71	70.382	ENSSHAG00000013398	-	100	70.382	Sarcophilus_harrisii
ENSG00000254772	EEF1G	100	77.273	ENSSFOG00015001181	eef1g	100	78.507	Scleropages_formosus
ENSG00000254772	EEF1G	100	74.142	ENSSMAG00000001235	eef1g	100	74.658	Scophthalmus_maximus
ENSG00000254772	EEF1G	94	74.818	ENSSDUG00000015202	eef1g	99	74.757	Seriola_dumerili
ENSG00000254772	EEF1G	100	75.114	ENSSLDG00000001834	eef1g	100	75.057	Seriola_lalandi_dorsalis
ENSG00000254772	EEF1G	75	96.951	ENSSARG00000011232	EEF1G	100	96.951	Sorex_araneus
ENSG00000254772	EEF1G	99	83.603	ENSSPUG00000008624	EEF1G	97	85.219	Sphenodon_punctatus
ENSG00000254772	EEF1G	100	74.828	ENSSPAG00000015237	eef1g	100	75.342	Stegastes_partitus
ENSG00000254772	EEF1G	100	59.725	ENSSSCG00000034941	-	98	59.725	Sus_scrofa
ENSG00000254772	EEF1G	100	94.508	ENSSSCG00000013064	-	100	94.508	Sus_scrofa
ENSG00000254772	EEF1G	100	71.882	ENSTRUG00000003022	eef1g	100	72.523	Takifugu_rubripes
ENSG00000254772	EEF1G	100	70.709	ENSTNIG00000005909	eef1g	100	71.233	Tetraodon_nigroviridis
ENSG00000254772	EEF1G	56	98.675	ENSTBEG00000012860	-	62	98.675	Tupaia_belangeri
ENSG00000254772	EEF1G	99	97.936	ENSTTRG00000002459	-	100	97.936	Tursiops_truncatus
ENSG00000254772	EEF1G	100	99.085	ENSUAMG00000027238	-	100	99.085	Ursus_americanus
ENSG00000254772	EEF1G	100	99.085	ENSUMAG00000012578	-	100	99.085	Ursus_maritimus
ENSG00000254772	EEF1G	100	89.245	ENSVVUG00000014270	-	100	89.245	Vulpes_vulpes
ENSG00000254772	EEF1G	100	97.712	ENSVVUG00000029883	-	100	97.712	Vulpes_vulpes
ENSG00000254772	EEF1G	100	74.658	ENSXETG00000026372	eef1g	100	78.261	Xenopus_tropicalis
ENSG00000254772	EEF1G	100	74.828	ENSXCOG00000001996	eef1g	100	74.828	Xiphophorus_couchianus
ENSG00000254772	EEF1G	100	75.057	ENSXMAG00000010070	eef1g	100	75.057	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003746	translation elongation factor activity	-	IEA	Function
GO:0005515	protein binding	10908348.16169070.16189514.17906640.18157088.27018634.30021884.	IPI	Function
GO:0005634	nucleus	21630459.	HDA	Component
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	8743958.25468996.	IDA	Component
GO:0005783	endoplasmic reticulum	8743958.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006414	translational elongation	21873635.	IBA	Process
GO:0006414	translational elongation	-	TAS	Process
GO:0009615	response to virus	16548883.	IEP	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0045296	cadherin binding	25468996.	HDA	Function
GO:0070062	extracellular exosome	23533145.	HDA	Component

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr11	62566885	Missense_Mutation	novel	E260K	0.22
BLCA	chr11	62566864	Missense_Mutation	NA	E267K	0.36
BLCA	chr11	62560162	Missense_Mutation	NA	K354N	0.69	EF1G
BLCA	chr11	62573907	5'UTR	novel		0.16
BRCA	chr11	62560291	Missense_Mutation	novel	L341V	0.1	EF1G
BRCA	chr11	62571021	Nonsense_Mutation	novel	R156*	0.09
BRCA	chr11	62572678	Missense_Mutation	NA	G26E	0.27
CESC	chr11	62560347	Nonsense_Mutation	NA	W322*	0.24	EF1G
CESC	chr11	62559775	Silent	rs777007816	S406S	0.34
CESC	chr11	62566857	Missense_Mutation	rs372879019	A269V	0.44
COAD	chr11	62560069	Splice_Region	rs375447576	P385P	0.28
COAD	chr11	62571872	Missense_Mutation	novel	F67L	0.38
COAD	chr11	62572604	Missense_Mutation	novel	R51C	0.3
ESCA	chr11	62560291	Missense_Mutation	novel	L341V	0.16	EF1G
HNSC	chr11	62560120	Silent	novel	S368S	0.42
HNSC	chr11	62572688	Nonsense_Mutation	novel	Q23*	0.15
HNSC	chr11	62573861	5'UTR	novel		0.27
KIRC	chr11	62571643	Missense_Mutation	NA	A92V	0.21
KIRP	chr11	62560285	Missense_Mutation	novel	T343S	0.38	EF1G
KIRP	chr11	62567440	Missense_Mutation	NA	L204W	0.31
LIHC	chr11	62566986	Missense_Mutation	novel	P226L	0.31
LIHC	chr11	62567518	Missense_Mutation	NA	P178R	0.21
LIHC	chr11	62560441	Missense_Mutation	novel	D291N	0.23	EF1G
LUAD	chr11	62560339	Frame_Shift_Ins	novel	*E325Rfs6**	0.5	EF1G
LUAD	chr11	62572729	Missense_Mutation	novel	Y9F	0.19
LUAD	chr11	62571630	Silent	novel	V96V	0.23
LUSC	chr11	62571573	Silent	NA	F115F	0.29
LUSC	chr11	62572657	Missense_Mutation	rs368954257	S33C	0.3
LUSC	chr11	62567436	Frame_Shift_Del	novel	*E206Kfs2**	0.38
LUSC	chr11	62566876	Missense_Mutation	novel	M263L	0.33
LUSC	chr11	62573925	5'UTR	novel		0.12
OV	chr11	62573833	Missense_Mutation	NA	G4W	0.36
OV	chr11	62559830	Missense_Mutation	novel	P388Q	0.2
OV	chr11	62559811	Nonsense_Mutation	novel	Y394*	0.32
OV	chr11	62559813	Missense_Mutation	rs370127965	Y394H	0.31
PAAD	chr11	62560166	Missense_Mutation	novel	R353M	0.19	EF1G
PAAD	chr11	62567459	Missense_Mutation	novel	P198T	0.2
PAAD	chr11	62573917	5'UTR	novel		0.19
PRAD	chr11	62560092	Nonsense_Mutation	novel	R378*	0.36	EF1G
READ	chr11	62559635	3'UTR	novel		0.25
SARC	chr11	62571855	Missense_Mutation	rs752473849	N73S	0.4
SARC	chr11	62560182	Nonsense_Mutation	novel	R348*	0.1	EF1G
SKCM	chr11	62571106	Splice_Region	novel	A127A	0.28
SKCM	chr11	62560307	Silent	novel	T335T	0.49
SKCM	chr11	62560308	Missense_Mutation	novel	T335I	0.49	EF1G
SKCM	chr11	62559682	Silent	NA	K437K	0.33
SKCM	chr11	62559684	Missense_Mutation	NA	K437E	0.33
SKCM	chr11	62560186	Silent	NA	F346F	0.29
SKCM	chr11	62567455	Missense_Mutation	NA	Q199R	0.2
SKCM	chr11	62572595	Missense_Mutation	rs11549641	P54S	0.37
SKCM	chr11	62559753	Nonsense_Mutation	NA	R414*	0.33
SKCM	chr11	62559740	Missense_Mutation	NA	S418F	0.39
SKCM	chr11	62571567	Silent	NA	T117T	0.3
SKCM	chr11	62571899	Splice_Region	novel	V58V	0.38
SKCM	chr11	62573962	5'UTR	novel		0.63
SKCM	chr11	62560319	Silent	NA	E331E	0.36
STAD	chr11	62571077	Missense_Mutation	NA	R137Q	0.1
STAD	chr11	62560319	Silent	NA	E331E	0.44
STAD	chr11	62559605	3'UTR	novel		0.54
STAD	chr11	62571025	Silent	rs377391262	G154G	0.22
UCEC	chr11	62571074	Missense_Mutation	novel	I138N	0.21
UCEC	chr11	62571043	Silent	rs753272618	T148T	0.32
UCEC	chr11	62571868	Missense_Mutation	novel	V69L	0.06
UCEC	chr11	62559796	Missense_Mutation	novel	W399C	0.08
UCEC	chr11	62571860	Missense_Mutation	NA	E71D	0.14
UCEC	chr11	62559739	Silent	novel	S418S	0.28
UCEC	chr11	62571566	Missense_Mutation	NA	L118V	0.4
UCEC	chr11	62571632	Missense_Mutation	novel	V96M	0.15
UCEC	chr11	62560361	Silent	rs748458661	D317D	0.22
UCEC	chr11	62571876	Missense_Mutation	NA	G66E	0.29
UCEC	chr11	62572665	Silent	NA	R30R	0.32
UCEC	chr11	62559667	3'UTR	novel		0.2
UCEC	chr11	62571872	Silent	NA	F67F	0.16
UCEC	chr11	62566855	Silent	NA	L270L	0.43
UCEC	chr11	62566943	Missense_Mutation	novel	E240D	0.41
UCEC	chr11	62567397	Splice_Site	novel	X218_splice	0.26
UCEC	chr11	62567503	Missense_Mutation	rs377344394	A183D	0.31
UCEC	chr11	62571613	Missense_Mutation	rs17851072	A102V	0.24
UCEC	chr11	62567435	Missense_Mutation	rs754430580	E206K	0.17
UCEC	chr11	62571894	Missense_Mutation	NA	A60V	0.31
UCEC	chr11	62560087	Silent	NA	G379G	0.31
UCEC	chr11	62570985	Frame_Shift_Del	novel	*L168Cfs9**	0.43
UCEC	chr11	62559747	Missense_Mutation	novel	Y416H	0.26
UCEC	chr11	62567503	Missense_Mutation	novel	A183V	0.24
UCEC	chr11	62559677	3'UTR	novel		0.07
UCEC	chr11	62570979	Missense_Mutation	novel	W170R	0.44
UCEC	chr11	62572667	Missense_Mutation	NA	R30C	0.38
UCEC	chr11	62559667	3'UTR	novel		0.19
UCEC	chr11	62560153	Silent	NA	F357F	0.16
UCEC	chr11	62571100	Missense_Mutation	rs199942278	E129D	0.24
UCEC	chr11	62570968	Silent	NA	K173K	0.32
UCEC	chr11	62560321	Nonsense_Mutation	novel	E331*	0.38	EF1G

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ESCA	AMP	0.1685	0.018342
TGCT	DEL	0.7067	0.21504

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0041	Kaplan-Meier Survival Analysis
SARC	0.018	Kaplan-Meier Survival Analysis
ACC	0.0021	Kaplan-Meier Survival Analysis
SKCM	0.027	Kaplan-Meier Survival Analysis
PCPG	0.033	Kaplan-Meier Survival Analysis
UCEC	0.026	Kaplan-Meier Survival Analysis
LIHC	0.0026	Kaplan-Meier Survival Analysis
LGG	0.00011	Kaplan-Meier Survival Analysis