EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000257218 (Gene tree)
Gene ID: 283459
Gene Symbol: GATC
Alias: FLJ37000|15E1.2|gatC
Full Name: glutamyl-tRNA amidotransferase subunit C
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 17,316 bases
Position: chr12:120,446,438-120,463,753
Accession: 25068
RBP type: canonical RBP
Summary: (Glutamyl-TRNA Amidotransferase Subunit C) is a Protein Coding gene. Among its related pathways are Metabolism and tRNA Aminoacylation. Gene Ontology (GO) annotations related to this gene include glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. An important paralog of this gene is ENSG00000111780.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000446872	Glu-tRNAGln	PF02686.15	3.8e-09	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000548171	GATC-202	931	-	ENSP00000448397	121 (aa)	-	F8VRU3
ENST00000229384	GATC-201	372	-	ENSP00000229384	47 (aa)	-	J3KMY1
ENST00000551765	GATC-203	4244	-	ENSP00000446872	136 (aa)	-	O43716

Gene Model

Click here to download ENSG00000257218's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa00970	Aminoacyl-tRNA biosynthesis	KEGG
hsa01100	Metabolic pathways	KEGG

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000257218	rs1794735	12	120453513	?	Adolescent idiopathic scoliosis	30019117			EFO_0005423

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000257218's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000257218	GATC	100	93.617	ENSAMEG00000013298	-	100	84.559	Ailuropoda_melanoleuca
ENSG00000257218	GATC	94	72.727	ENSACIG00000016853	gatc	66	65.217	Amphilophus_citrinellus
ENSG00000257218	GATC	100	74.468	ENSAOCG00000014641	gatc	81	63.366	Amphiprion_ocellaris
ENSG00000257218	GATC	100	74.468	ENSAPEG00000023411	gatc	52	63.366	Amphiprion_percula
ENSG00000257218	GATC	100	68.085	ENSATEG00000009237	gatc	87	60.000	Anabas_testudineus
ENSG00000257218	GATC	100	70.213	ENSACAG00000002868	-	81	62.385	Anolis_carolinensis
ENSG00000257218	GATC	100	97.872	ENSANAG00000034389	-	100	92.647	Aotus_nancymaae
ENSG00000257218	GATC	100	72.340	ENSACLG00000026251	gatc	53	64.356	Astatotilapia_calliptera
ENSG00000257218	GATC	98	95.652	ENSBTAG00000012791	GATC	99	83.704	Bos_taurus
ENSG00000257218	GATC	69	42.553	WBGene00013433	Y66D12A.7	54	42.553	Caenorhabditis_elegans
ENSG00000257218	GATC	100	97.872	ENSCJAG00000001183	-	75	92.647	Callithrix_jacchus
ENSG00000257218	GATC	100	95.745	ENSCAFG00000010311	-	100	83.824	Canis_familiaris
ENSG00000257218	GATC	100	95.745	ENSCAFG00020020606	-	100	83.824	Canis_lupus_dingo
ENSG00000257218	GATC	98	97.826	ENSCHIG00000019423	-	99	84.444	Capra_hircus
ENSG00000257218	GATC	100	91.489	ENSTSYG00000006845	-	100	88.971	Carlito_syrichta
ENSG00000257218	GATC	91	90.698	ENSCPOG00000026436	-	94	73.913	Cavia_porcellus
ENSG00000257218	GATC	100	97.872	ENSCCAG00000022235	-	100	92.647	Cebus_capucinus
ENSG00000257218	GATC	100	100.000	ENSCATG00000038807	GATC	100	98.529	Cercocebus_atys
ENSG00000257218	GATC	100	93.617	ENSCLAG00000011015	-	96	71.242	Chinchilla_lanigera
ENSG00000257218	GATC	100	100.000	ENSCSAG00000002259	GATC	100	98.529	Chlorocebus_sabaeus
ENSG00000257218	GATC	100	93.617	ENSCHOG00000009235	-	99	80.000	Choloepus_hoffmanni
ENSG00000257218	GATC	100	72.340	ENSCPBG00000011342	-	55	67.961	Chrysemys_picta_bellii
ENSG00000257218	GATC	100	100.000	ENSCANG00000031071	GATC	100	96.324	Colobus_angolensis_palliatus
ENSG00000257218	GATC	100	76.596	ENSCGRG00001005508	-	75	61.842	Cricetulus_griseus_chok1gshd
ENSG00000257218	GATC	100	85.106	ENSCGRG00001019220	-	98	65.132	Cricetulus_griseus_chok1gshd
ENSG00000257218	GATC	100	85.106	ENSCGRG00000004184	-	98	65.132	Cricetulus_griseus_crigri
ENSG00000257218	GATC	100	76.596	ENSCGRG00000019471	GATC	75	61.184	Cricetulus_griseus_crigri
ENSG00000257218	GATC	100	70.213	ENSCSEG00000007798	gatc	50	60.000	Cynoglossus_semilaevis
ENSG00000257218	GATC	100	65.957	ENSCSEG00000016618	-	65	54.054	Cynoglossus_semilaevis
ENSG00000257218	GATC	100	72.340	ENSCVAG00000004364	gatc	53	63.000	Cyprinodon_variegatus
ENSG00000257218	GATC	100	70.213	ENSDARG00000056855	gatc	55	64.706	Danio_rerio
ENSG00000257218	GATC	100	91.489	ENSDNOG00000012593	-	84	71.739	Dasypus_novemcinctus
ENSG00000257218	GATC	96	53.333	FBgn0064115	GatC	84	40.000	Drosophila_melanogaster
ENSG00000257218	GATC	97	69.697	ENSETEG00000002604	-	97	69.697	Echinops_telfairi
ENSG00000257218	GATC	100	40.426	ENSEBUG00000008772	gatc	66	43.697	Eptatretus_burgeri
ENSG00000257218	GATC	100	93.617	ENSECAG00000011118	-	99	88.148	Equus_caballus
ENSG00000257218	GATC	100	87.234	ENSEEUG00000011638	-	97	72.932	Erinaceus_europaeus
ENSG00000257218	GATC	100	72.340	ENSELUG00000012608	gatc	74	60.396	Esox_lucius
ENSG00000257218	GATC	100	91.489	ENSFCAG00000038718	-	100	83.088	Felis_catus
ENSG00000257218	GATC	100	74.468	ENSFALG00000007564	-	77	62.393	Ficedula_albicollis
ENSG00000257218	GATC	100	89.362	ENSFDAG00000018720	-	100	83.824	Fukomys_damarensis
ENSG00000257218	GATC	100	68.085	ENSFHEG00000014992	GATC	54	61.000	Fundulus_heteroclitus
ENSG00000257218	GATC	100	61.702	ENSGMOG00000008742	gatc	68	55.455	Gadus_morhua
ENSG00000257218	GATC	100	72.340	ENSGALG00000007195	-	77	61.111	Gallus_gallus
ENSG00000257218	GATC	100	68.085	ENSGAFG00000012801	gatc	65	60.194	Gambusia_affinis
ENSG00000257218	GATC	100	70.213	ENSGACG00000008973	gatc	51	63.636	Gasterosteus_aculeatus
ENSG00000257218	GATC	100	76.596	ENSGAGG00000016018	-	57	69.903	Gopherus_agassizii
ENSG00000257218	GATC	94	97.727	ENSGGOG00000026821	GATC	94	98.347	Gorilla_gorilla
ENSG00000257218	GATC	100	72.340	ENSHBUG00000006827	gatc	53	64.356	Haplochromis_burtoni
ENSG00000257218	GATC	100	93.617	ENSHGLG00000011394	GATC	100	87.500	Heterocephalus_glaber_female
ENSG00000257218	GATC	100	93.617	ENSHGLG00100018850	-	100	83.824	Heterocephalus_glaber_male
ENSG00000257218	GATC	100	70.213	ENSHCOG00000009209	gatc	90	55.906	Hippocampus_comes
ENSG00000257218	GATC	100	72.340	ENSIPUG00000023072	gatc	51	65.000	Ictalurus_punctatus
ENSG00000257218	GATC	100	91.489	ENSSTOG00000025740	-	88	85.075	Ictidomys_tridecemlineatus
ENSG00000257218	GATC	100	78.723	ENSJJAG00000000369	Gatc	98	63.871	Jaculus_jaculus
ENSG00000257218	GATC	100	65.957	ENSKMAG00000016476	gatc	77	60.825	Kryptolebias_marmoratus
ENSG00000257218	GATC	100	72.340	ENSLBEG00000007603	gatc	56	62.376	Labrus_bergylta
ENSG00000257218	GATC	100	65.957	ENSLACG00000018239	-	52	65.000	Latimeria_chalumnae
ENSG00000257218	GATC	100	70.213	ENSLOCG00000004056	gatc	54	62.000	Lepisosteus_oculatus
ENSG00000257218	GATC	91	95.349	ENSLAFG00000006384	-	90	75.182	Loxodonta_africana
ENSG00000257218	GATC	100	100.000	ENSMFAG00000034197	GATC	100	98.529	Macaca_fascicularis
ENSG00000257218	GATC	100	100.000	ENSMMUG00000046665	GATC	100	98.529	Macaca_mulatta
ENSG00000257218	GATC	100	100.000	ENSMNEG00000034653	GATC	100	98.529	Macaca_nemestrina
ENSG00000257218	GATC	100	100.000	ENSMLEG00000039862	GATC	100	97.794	Mandrillus_leucophaeus
ENSG00000257218	GATC	100	72.340	ENSMAMG00000015851	gatc	55	65.000	Mastacembelus_armatus
ENSG00000257218	GATC	100	72.340	ENSMZEG00005016072	gatc	53	64.356	Maylandia_zebra
ENSG00000257218	GATC	100	72.340	ENSMGAG00000008733	-	96	64.706	Meleagris_gallopavo
ENSG00000257218	GATC	100	87.234	ENSMAUG00000012756	Gatc	98	65.132	Mesocricetus_auratus
ENSG00000257218	GATC	100	97.872	ENSMICG00000008669	-	100	94.118	Microcebus_murinus
ENSG00000257218	GATC	100	87.234	ENSMOCG00000005051	Gatc	98	64.474	Microtus_ochrogaster
ENSG00000257218	GATC	100	70.213	ENSMMOG00000017695	gatc	83	60.606	Mola_mola
ENSG00000257218	GATC	100	82.979	ENSMODG00000003152	-	100	66.667	Monodelphis_domestica
ENSG00000257218	GATC	100	87.234	MGP_CAROLIEiJ_G0027623	Gatc	97	66.000	Mus_caroli
ENSG00000257218	GATC	100	87.234	ENSMUSG00000029536	Gatc	97	66.667	Mus_musculus
ENSG00000257218	GATC	100	85.106	MGP_PahariEiJ_G0024203	Gatc	97	63.333	Mus_pahari
ENSG00000257218	GATC	100	87.234	MGP_SPRETEiJ_G0028621	Gatc	97	66.667	Mus_spretus
ENSG00000257218	GATC	100	91.489	ENSMPUG00000003183	-	98	87.218	Mustela_putorius_furo
ENSG00000257218	GATC	100	93.617	ENSMLUG00000010341	-	100	88.119	Myotis_lucifugus
ENSG00000257218	GATC	96	88.889	ENSNGAG00000004734	Gatc	99	66.452	Nannospalax_galili
ENSG00000257218	GATC	100	72.340	ENSNBRG00000007810	gatc	53	64.356	Neolamprologus_brichardi
ENSG00000257218	GATC	100	97.872	ENSNLEG00000015651	GATC	100	95.588	Nomascus_leucogenys
ENSG00000257218	GATC	100	78.723	ENSMEUG00000004064	-	96	63.636	Notamacropus_eugenii
ENSG00000257218	GATC	100	91.489	ENSOPRG00000004226	-	100	83.088	Ochotona_princeps
ENSG00000257218	GATC	91	90.698	ENSODEG00000005919	-	91	79.200	Octodon_degus
ENSG00000257218	GATC	100	69.388	ENSONIG00000013444	gatc	71	62.136	Oreochromis_niloticus
ENSG00000257218	GATC	100	95.745	ENSOCUG00000009867	-	100	88.235	Oryctolagus_cuniculus
ENSG00000257218	GATC	100	68.085	ENSORLG00000007156	gatc	83	64.835	Oryzias_latipes
ENSG00000257218	GATC	100	68.085	ENSORLG00020014991	gatc	54	59.406	Oryzias_latipes_hni
ENSG00000257218	GATC	100	68.085	ENSORLG00015003450	gatc	54	60.396	Oryzias_latipes_hsok
ENSG00000257218	GATC	100	65.957	ENSOMEG00000002280	gatc	53	59.000	Oryzias_melastigma
ENSG00000257218	GATC	100	91.489	ENSOGAG00000003850	-	100	88.991	Otolemur_garnettii
ENSG00000257218	GATC	100	95.745	ENSOARG00000012338	-	91	83.761	Ovis_aries
ENSG00000257218	GATC	100	100.000	ENSPPAG00000029164	GATC	100	99.265	Pan_paniscus
ENSG00000257218	GATC	100	93.617	ENSPPRG00000000929	-	100	84.559	Panthera_pardus
ENSG00000257218	GATC	100	93.617	ENSPTIG00000009889	-	100	84.559	Panthera_tigris_altaica
ENSG00000257218	GATC	100	100.000	ENSPTRG00000049887	GATC	100	98.529	Pan_troglodytes
ENSG00000257218	GATC	100	100.000	ENSPANG00000033975	GATC	100	97.794	Papio_anubis
ENSG00000257218	GATC	100	59.574	ENSPKIG00000024856	gatc	52	56.436	Paramormyrops_kingsleyae
ENSG00000257218	GATC	100	70.213	ENSPSIG00000011112	-	92	64.815	Pelodiscus_sinensis
ENSG00000257218	GATC	100	76.596	ENSPMGG00000018829	gatc	61	67.368	Periophthalmus_magnuspinnatus
ENSG00000257218	GATC	100	82.979	ENSPEMG00000000665	Gatc	98	64.474	Peromyscus_maniculatus_bairdii
ENSG00000257218	GATC	94	77.273	ENSPCIG00000025999	-	91	58.571	Phascolarctos_cinereus
ENSG00000257218	GATC	100	70.213	ENSPFOG00000011603	gatc	56	61.905	Poecilia_formosa
ENSG00000257218	GATC	100	68.085	ENSPLAG00000002471	gatc	56	60.952	Poecilia_latipinna
ENSG00000257218	GATC	100	70.213	ENSPMEG00000020958	gatc	56	61.905	Poecilia_mexicana
ENSG00000257218	GATC	100	70.213	ENSPREG00000022256	gatc	89	57.252	Poecilia_reticulata
ENSG00000257218	GATC	100	97.872	ENSPPYG00000005030	GATC	100	96.324	Pongo_abelii
ENSG00000257218	GATC	98	91.304	ENSPCAG00000013864	-	99	83.704	Procavia_capensis
ENSG00000257218	GATC	99	82.090	ENSPCOG00000015558	-	98	82.090	Propithecus_coquereli
ENSG00000257218	GATC	91	97.674	ENSPCOG00000009493	-	93	93.333	Propithecus_coquereli
ENSG00000257218	GATC	100	95.745	ENSPVAG00000002228	-	99	85.185	Pteropus_vampyrus
ENSG00000257218	GATC	100	72.340	ENSPNYG00000016015	gatc	53	64.356	Pundamilia_nyererei
ENSG00000257218	GATC	100	82.979	ENSRNOG00000001161	Gatc	94	62.759	Rattus_norvegicus
ENSG00000257218	GATC	96	80.000	ENSRNOG00000045621	Gatc	92	62.143	Rattus_norvegicus
ENSG00000257218	GATC	100	100.000	ENSRBIG00000033363	GATC	100	96.324	Rhinopithecus_bieti
ENSG00000257218	GATC	100	100.000	ENSRROG00000042802	GATC	100	96.324	Rhinopithecus_roxellana
ENSG00000257218	GATC	100	95.745	ENSSBOG00000033750	-	100	91.912	Saimiri_boliviensis_boliviensis
ENSG00000257218	GATC	100	80.851	ENSSHAG00000005745	-	100	72.642	Sarcophilus_harrisii
ENSG00000257218	GATC	100	63.830	ENSSFOG00015002508	gatc	84	44.361	Scleropages_formosus
ENSG00000257218	GATC	100	76.596	ENSSMAG00000014280	gatc	56	64.356	Scophthalmus_maximus
ENSG00000257218	GATC	100	74.468	ENSSDUG00000012206	gatc	52	64.356	Seriola_dumerili
ENSG00000257218	GATC	100	74.468	ENSSLDG00000025159	gatc	51	64.356	Seriola_lalandi_dorsalis
ENSG00000257218	GATC	100	70.213	ENSSPUG00000015693	-	83	60.870	Sphenodon_punctatus
ENSG00000257218	GATC	100	74.468	ENSSPAG00000011860	gatc	53	63.366	Stegastes_partitus
ENSG00000257218	GATC	91	95.349	ENSSSCG00000032747	-	88	86.667	Sus_scrofa
ENSG00000257218	GATC	100	74.468	ENSTGUG00000009561	-	95	66.990	Taeniopygia_guttata
ENSG00000257218	GATC	100	68.085	ENSTRUG00000021596	gatc	51	60.000	Takifugu_rubripes
ENSG00000257218	GATC	100	95.745	ENSTTRG00000000144	GATC	99	88.889	Tursiops_truncatus
ENSG00000257218	GATC	100	93.617	ENSUAMG00000015523	-	100	85.294	Ursus_americanus
ENSG00000257218	GATC	100	95.745	ENSVVUG00000021055	-	100	83.824	Vulpes_vulpes
ENSG00000257218	GATC	100	70.213	ENSXCOG00000017087	gatc	73	63.000	Xiphophorus_couchianus
ENSG00000257218	GATC	100	70.213	ENSXMAG00000018267	gatc	54	63.000	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	19805282.25416956.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005739	mitochondrion	19805282.	IDA	Component
GO:0006450	regulation of translational fidelity	-	IEA	Process
GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex	19805282.	IDA	Component
GO:0032543	mitochondrial translation	19805282.	IMP	Process
GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity	19805282.	IDA	Function
GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation	19805282.	IDA	Process