EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000265817 (Gene tree)
Gene ID: 100861412
Gene Symbol: FSBP
Alias: -
Full Name: fibrinogen silencer binding protein
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 64,783 bases
Position: chr8:94,372,170-94,436,952
Accession: 43653
RBP type: canonical RBP
Summary: FSBP (Fibrinogen Silencer Binding Protein) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include identical protein binding. An important paralog of this gene is RAD54B.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000483397	ResIII	PF04851.15	3e-11	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000481490	FSBP-201	1158	-	ENSP00000420405	299 (aa)	-	O95073
ENST00000611249	FSBP-203	2181	-	ENSP00000483397	726 (aa)	-	A0A087X0H2
ENST00000517506	FSBP-202	2472	-	ENSP00000462684	129 (aa)	-	J3KSW4

Gene Model

Click here to download ENSG00000265817's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03440	Homologous recombination	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000265817	Albuminuria	4.59422506867576E-6	17903292
ENSG00000265817	Albuminuria	4.59422506867576E-6	17903292
ENSG00000265817	Albuminuria	4.70257164258101E-6	17903292
ENSG00000265817	Albuminuria	1.03224982790978E-6	17903292
ENSG00000265817	Albuminuria	1.03224982790978E-6	17903292
ENSG00000265817	Albuminuria	2.38864732764305E-6	17903292
ENSG00000265817	Cleft Lip	2E-10	28232668
ENSG00000265817	Cleft Palate	2E-10	28232668

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000265817	rs12681366	8	94389037	A	Nonsyndromic cleft lip with cleft palate	28232668	[NR]	1.2048193	HP_0000175\|EFO_0003959

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000265817's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000265817	FSBP	99	90.621	ENSAMEG00000005834	-	80	90.621	Ailuropoda_melanoleuca
ENSG00000265817	FSBP	99	58.470	ENSACIG00000013005	rad54b	82	58.470	Amphilophus_citrinellus
ENSG00000265817	FSBP	99	59.128	ENSAOCG00000008523	rad54b	79	59.128	Amphiprion_ocellaris
ENSG00000265817	FSBP	99	58.470	ENSAPEG00000001673	rad54b	82	58.607	Amphiprion_percula
ENSG00000265817	FSBP	99	58.038	ENSATEG00000001527	rad54b	83	57.844	Anabas_testudineus
ENSG00000265817	FSBP	99	75.657	ENSAPLG00000014366	-	79	75.657	Anas_platyrhynchos
ENSG00000265817	FSBP	100	70.702	ENSACAG00000003671	-	90	70.702	Anolis_carolinensis
ENSG00000265817	FSBP	89	95.069	ENSANAG00000019528	-	100	95.069	Aotus_nancymaae
ENSG00000265817	FSBP	99	57.866	ENSACLG00000007826	rad54b	84	57.866	Astatotilapia_calliptera
ENSG00000265817	FSBP	99	57.084	ENSAMXG00000039985	rad54b	87	56.812	Astyanax_mexicanus
ENSG00000265817	FSBP	99	88.690	ENSBTAG00000000632	RAD54B	80	88.690	Bos_taurus
ENSG00000265817	FSBP	75	40.253	WBGene00013792	Y116A8C.13	88	36.458	Caenorhabditis_elegans
ENSG00000265817	FSBP	100	96.694	ENSCJAG00000000080	-	100	96.694	Callithrix_jacchus
ENSG00000265817	FSBP	99	88.966	ENSCAFG00000009179	RAD54B	79	88.966	Canis_familiaris
ENSG00000265817	FSBP	99	88.828	ENSCAFG00020012084	-	79	88.828	Canis_lupus_dingo
ENSG00000265817	FSBP	99	88.276	ENSCHIG00000008230	-	80	88.276	Capra_hircus
ENSG00000265817	FSBP	99	91.310	ENSTSYG00000013234	-	80	91.310	Carlito_syrichta
ENSG00000265817	FSBP	99	88.812	ENSCPOG00000011643	-	80	88.812	Cavia_porcellus
ENSG00000265817	FSBP	100	96.419	ENSCCAG00000011754	-	100	96.419	Cebus_capucinus
ENSG00000265817	FSBP	100	98.485	ENSCATG00000030661	-	100	98.485	Cercocebus_atys
ENSG00000265817	FSBP	100	88.705	ENSCLAG00000010476	-	82	88.705	Chinchilla_lanigera
ENSG00000265817	FSBP	100	98.209	ENSCSAG00000012712	-	80	98.209	Chlorocebus_sabaeus
ENSG00000265817	FSBP	100	76.236	ENSCPBG00000003204	-	79	76.236	Chrysemys_picta_bellii
ENSG00000265817	FSBP	100	98.347	ENSCANG00000017939	-	100	98.347	Colobus_angolensis_palliatus
ENSG00000265817	FSBP	99	84.116	ENSCGRG00001020184	Rad54b	82	84.116	Cricetulus_griseus_chok1gshd
ENSG00000265817	FSBP	99	82.735	ENSCGRG00000016752	Rad54b	81	82.735	Cricetulus_griseus_crigri
ENSG00000265817	FSBP	99	57.123	ENSCSEG00000001601	rad54b	85	57.123	Cynoglossus_semilaevis
ENSG00000265817	FSBP	99	60.246	ENSCVAG00000009200	rad54b	82	60.246	Cyprinodon_variegatus
ENSG00000265817	FSBP	99	57.981	ENSDARG00000092134	rad54b	99	60.615	Danio_rerio
ENSG00000265817	FSBP	99	88.187	ENSDNOG00000015535	-	80	88.187	Dasypus_novemcinctus
ENSG00000265817	FSBP	99	89.365	ENSDORG00000002492	Rad54b	83	89.365	Dipodomys_ordii
ENSG00000265817	FSBP	83	87.748	ENSETEG00000010605	-	77	87.748	Echinops_telfairi
ENSG00000265817	FSBP	100	49.064	ENSEBUG00000009104	rad54b	78	49.064	Eptatretus_burgeri
ENSG00000265817	FSBP	99	88.276	ENSEASG00005004021	-	82	88.276	Equus_asinus_asinus
ENSG00000265817	FSBP	98	96.825	ENSECAG00000021949	-	85	88.690	Equus_caballus
ENSG00000265817	FSBP	88	81.761	ENSEEUG00000008056	-	70	81.761	Erinaceus_europaeus
ENSG00000265817	FSBP	99	59.097	ENSELUG00000009287	rad54b	77	59.097	Esox_lucius
ENSG00000265817	FSBP	99	90.608	ENSFCAG00000015513	-	99	90.608	Felis_catus
ENSG00000265817	FSBP	99	75.242	ENSFALG00000005467	-	79	75.242	Ficedula_albicollis
ENSG00000265817	FSBP	98	89.124	ENSFDAG00000020541	-	80	88.536	Fukomys_damarensis
ENSG00000265817	FSBP	99	57.473	ENSFHEG00000014382	rad54b	80	57.588	Fundulus_heteroclitus
ENSG00000265817	FSBP	99	55.210	ENSGMOG00000014774	rad54b	91	55.210	Gadus_morhua
ENSG00000265817	FSBP	100	74.176	ENSGALG00000043597	RAD54B	79	74.176	Gallus_gallus
ENSG00000265817	FSBP	99	58.607	ENSGAFG00000007901	rad54b	84	58.607	Gambusia_affinis
ENSG00000265817	FSBP	99	58.266	ENSGACG00000009128	rad54b	79	58.266	Gasterosteus_aculeatus
ENSG00000265817	FSBP	100	75.824	ENSGAGG00000018747	-	79	75.824	Gopherus_agassizii
ENSG00000265817	FSBP	99	99.724	ENSGGOG00000023516	-	80	99.724	Gorilla_gorilla
ENSG00000265817	FSBP	99	58.060	ENSHBUG00000016017	rad54b	78	58.060	Haplochromis_burtoni
ENSG00000265817	FSBP	99	87.534	ENSHGLG00000008263	RAD54B	79	87.534	Heterocephalus_glaber_female
ENSG00000265817	FSBP	99	86.413	ENSHGLG00100008108	-	79	86.413	Heterocephalus_glaber_male
ENSG00000265817	FSBP	99	56.772	ENSHCOG00000004764	rad54b	90	55.481	Hippocampus_comes
ENSG00000265817	FSBP	99	57.844	ENSIPUG00000018531	rad54b	77	57.844	Ictalurus_punctatus
ENSG00000265817	FSBP	99	88.750	ENSSTOG00000010791	-	79	88.750	Ictidomys_tridecemlineatus
ENSG00000265817	FSBP	99	86.464	ENSJJAG00000010314	Rad54b	80	86.464	Jaculus_jaculus
ENSG00000265817	FSBP	99	57.045	ENSKMAG00000004744	rad54b	84	57.045	Kryptolebias_marmoratus
ENSG00000265817	FSBP	99	69.583	ENSLACG00000000859	-	97	69.583	Latimeria_chalumnae
ENSG00000265817	FSBP	99	63.636	ENSLOCG00000010100	rad54b	86	63.574	Lepisosteus_oculatus
ENSG00000265817	FSBP	100	88.981	ENSLAFG00000015315	-	90	88.981	Loxodonta_africana
ENSG00000265817	FSBP	100	98.209	ENSMFAG00000031629	-	100	98.209	Macaca_fascicularis
ENSG00000265817	FSBP	100	98.209	ENSMMUG00000005659	-	80	98.209	Macaca_mulatta
ENSG00000265817	FSBP	100	98.209	ENSMNEG00000016408	-	80	98.209	Macaca_nemestrina
ENSG00000265817	FSBP	100	98.623	ENSMLEG00000006946	-	80	98.623	Mandrillus_leucophaeus
ENSG00000265817	FSBP	99	58.593	ENSMAMG00000012269	rad54b	82	58.593	Mastacembelus_armatus
ENSG00000265817	FSBP	99	58.060	ENSMZEG00005005281	rad54b	87	57.866	Maylandia_zebra
ENSG00000265817	FSBP	100	74.038	ENSMGAG00000012024	-	79	74.038	Meleagris_gallopavo
ENSG00000265817	FSBP	99	83.840	ENSMAUG00000013586	Rad54b	82	83.840	Mesocricetus_auratus
ENSG00000265817	FSBP	99	91.034	ENSMICG00000000754	-	83	91.034	Microcebus_murinus
ENSG00000265817	FSBP	99	81.655	ENSMOCG00000020035	Rad54b	81	81.655	Microtus_ochrogaster
ENSG00000265817	FSBP	99	57.945	ENSMMOG00000003394	rad54b	82	57.945	Mola_mola
ENSG00000265817	FSBP	99	79.668	ENSMODG00000007343	-	89	79.668	Monodelphis_domestica
ENSG00000265817	FSBP	89	59.070	ENSMALG00000001520	rad54b	99	59.070	Monopterus_albus
ENSG00000265817	FSBP	99	83.149	MGP_CAROLIEiJ_G0025810	Rad54b	81	83.149	Mus_caroli
ENSG00000265817	FSBP	99	82.849	ENSMUSG00000078773	Rad54b	81	82.849	Mus_musculus
ENSG00000265817	FSBP	99	83.679	MGP_PahariEiJ_G0023933	Rad54b	81	83.679	Mus_pahari
ENSG00000265817	FSBP	99	83.978	MGP_SPRETEiJ_G0026758	Rad54b	81	83.978	Mus_spretus
ENSG00000265817	FSBP	99	88.966	ENSMPUG00000008878	-	89	88.966	Mustela_putorius_furo
ENSG00000265817	FSBP	100	89.256	ENSMLUG00000008953	-	80	89.256	Myotis_lucifugus
ENSG00000265817	FSBP	99	87.517	ENSNGAG00000017537	Rad54b	81	87.517	Nannospalax_galili
ENSG00000265817	FSBP	99	58.082	ENSNBRG00000013394	rad54b	84	58.082	Neolamprologus_brichardi
ENSG00000265817	FSBP	100	99.174	ENSNLEG00000003062	-	99	99.174	Nomascus_leucogenys
ENSG00000265817	FSBP	78	79.503	ENSMEUG00000012426	-	62	79.503	Notamacropus_eugenii
ENSG00000265817	FSBP	93	88.938	ENSODEG00000002650	-	91	88.938	Octodon_degus
ENSG00000265817	FSBP	99	87.431	ENSODEG00000019564	-	80	87.431	Octodon_degus
ENSG00000265817	FSBP	99	58.413	ENSONIG00000006067	rad54b	80	58.413	Oreochromis_niloticus
ENSG00000265817	FSBP	99	77.931	ENSOANG00000011348	-	96	77.931	Ornithorhynchus_anatinus
ENSG00000265817	FSBP	99	90.345	ENSOCUG00000016478	-	80	90.345	Oryctolagus_cuniculus
ENSG00000265817	FSBP	99	59.537	ENSORLG00000008918	rad54b	99	61.824	Oryzias_latipes
ENSG00000265817	FSBP	89	61.978	ENSORLG00020012171	rad54b	99	61.978	Oryzias_latipes_hni
ENSG00000265817	FSBP	99	59.244	ENSORLG00015018536	rad54b	78	59.244	Oryzias_latipes_hsok
ENSG00000265817	FSBP	99	59.234	ENSOMEG00000004345	rad54b	94	59.234	Oryzias_melastigma
ENSG00000265817	FSBP	99	90.069	ENSOGAG00000007854	-	80	90.069	Otolemur_garnettii
ENSG00000265817	FSBP	99	88.000	ENSOARG00000007691	-	89	88.000	Ovis_aries
ENSG00000265817	FSBP	100	97.383	ENSPPAG00000029572	-	79	97.383	Pan_paniscus
ENSG00000265817	FSBP	99	90.746	ENSPPRG00000007571	-	99	90.746	Panthera_pardus
ENSG00000265817	FSBP	99	90.746	ENSPTIG00000012670	-	99	90.746	Panthera_tigris_altaica
ENSG00000265817	FSBP	100	99.725	ENSPTRG00000020427	-	100	99.725	Pan_troglodytes
ENSG00000265817	FSBP	100	98.623	ENSPANG00000019566	-	80	98.623	Papio_anubis
ENSG00000265817	FSBP	99	62.881	ENSPKIG00000014974	rad54b	78	62.881	Paramormyrops_kingsleyae
ENSG00000265817	FSBP	100	74.038	ENSPSIG00000002383	-	89	74.038	Pelodiscus_sinensis
ENSG00000265817	FSBP	99	83.425	ENSPEMG00000012133	Rad54b	81	83.425	Peromyscus_maniculatus_bairdii
ENSG00000265817	FSBP	100	58.209	ENSPMAG00000002916	rad54b	91	58.209	Petromyzon_marinus
ENSG00000265817	FSBP	100	80.441	ENSPCIG00000020151	-	85	79.890	Phascolarctos_cinereus
ENSG00000265817	FSBP	99	59.946	ENSPFOG00000023411	rad54b	77	59.946	Poecilia_formosa
ENSG00000265817	FSBP	99	59.946	ENSPLAG00000010430	rad54b	77	59.946	Poecilia_latipinna
ENSG00000265817	FSBP	99	59.946	ENSPMEG00000016873	rad54b	85	59.781	Poecilia_mexicana
ENSG00000265817	FSBP	99	59.754	ENSPREG00000018443	rad54b	83	59.754	Poecilia_reticulata
ENSG00000265817	FSBP	100	99.036	ENSPPYG00000018750	-	80	99.036	Pongo_abelii
ENSG00000265817	FSBP	99	91.448	ENSPCOG00000026845	-	99	91.448	Propithecus_coquereli
ENSG00000265817	FSBP	99	90.345	ENSPVAG00000000261	-	84	90.345	Pteropus_vampyrus
ENSG00000265817	FSBP	99	57.967	ENSPNYG00000018303	rad54b	88	57.967	Pundamilia_nyererei
ENSG00000265817	FSBP	100	58.209	ENSPNAG00000000295	rad54b	86	57.666	Pygocentrus_nattereri
ENSG00000265817	FSBP	99	80.801	ENSRNOG00000039949	Rad54b	81	80.801	Rattus_norvegicus
ENSG00000265817	FSBP	100	97.658	ENSRBIG00000020419	-	80	97.658	Rhinopithecus_bieti
ENSG00000265817	FSBP	100	97.658	ENSRROG00000039897	-	80	97.658	Rhinopithecus_roxellana
ENSG00000265817	FSBP	78	43.137	YBR073W	RDH54	61	43.137	Saccharomyces_cerevisiae
ENSG00000265817	FSBP	100	96.143	ENSSBOG00000028501	-	80	96.143	Saimiri_boliviensis_boliviensis
ENSG00000265817	FSBP	99	81.189	ENSSHAG00000017038	-	79	81.189	Sarcophilus_harrisii
ENSG00000265817	FSBP	79	65.614	ENSSFOG00015008483	rad54b	88	65.614	Scleropages_formosus
ENSG00000265817	FSBP	99	58.104	ENSSMAG00000018659	rad54b	83	57.713	Scophthalmus_maximus
ENSG00000265817	FSBP	98	59.059	ENSSDUG00000001122	rad54b	75	59.059	Seriola_dumerili
ENSG00000265817	FSBP	99	59.147	ENSSLDG00000013787	rad54b	84	54.297	Seriola_lalandi_dorsalis
ENSG00000265817	FSBP	100	73.901	ENSSPUG00000016497	-	82	73.901	Sphenodon_punctatus
ENSG00000265817	FSBP	99	58.752	ENSSPAG00000012800	rad54b	83	58.752	Stegastes_partitus
ENSG00000265817	FSBP	100	88.567	ENSSSCG00000006101	-	91	88.567	Sus_scrofa
ENSG00000265817	FSBP	99	74.483	ENSTGUG00000011880	-	79	74.483	Taeniopygia_guttata
ENSG00000265817	FSBP	99	58.470	ENSTRUG00000010015	rad54b	77	58.470	Takifugu_rubripes
ENSG00000265817	FSBP	99	84.530	ENSTTRG00000006312	-	80	84.530	Tursiops_truncatus
ENSG00000265817	FSBP	99	91.034	ENSUMAG00000016401	-	80	91.034	Ursus_maritimus
ENSG00000265817	FSBP	99	89.088	ENSVPAG00000003157	-	80	89.088	Vicugna_pacos
ENSG00000265817	FSBP	99	58.654	ENSXETG00000025924	rad54b	90	58.654	Xenopus_tropicalis
ENSG00000265817	FSBP	99	58.607	ENSXMAG00000013141	rad54b	84	58.607	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000724	double-strand break repair via homologous recombination	16428451.	IDA	Process
GO:0003677	DNA binding	-	IEA	Function
GO:0003678	DNA helicase activity	10362364.	TAS	Function
GO:0003724	RNA helicase activity	10362364.	TAS	Function
GO:0005515	protein binding	16189514.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	-	IEA	Component
GO:0006312	mitotic recombination	10362364.	TAS	Process
GO:0007131	reciprocal meiotic recombination	10362364.	TAS	Process
GO:0015616	DNA translocase activity	16428451.	IDA	Function
GO:0032508	DNA duplex unwinding	-	IEA	Process
GO:0005515	protein binding	20531236.25416956.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	20531236.	IDA	Component
GO:0042802	identical protein binding	19060904.25416956.	IPI	Function